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Journal articles on the topic 'Optos'

Author: Grafiati

Published: 25 June 2021

Last updated: 1 February 2022

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1

Nagasawa, Toshihiko, Hitoshi Tabuchi, Hiroki Masumoto, Shoji Morita, Masanori Niki, Zaigen Ohara, Yuki Yoshizumi, and Yoshinori Mitamura. "Accuracy of Diabetic Retinopathy Staging with a Deep Convolutional Neural Network Using Ultra-Wide-Field Fundus Ophthalmoscopy and Optical Coherence Tomography Angiography." Journal of Ophthalmology 2021 (April 3, 2021): 1–10. http://dx.doi.org/10.1155/2021/6651175.

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Purpose. The present study aimed to compare the accuracy of diabetic retinopathy (DR) staging with a deep convolutional neural network (DCNN) using two different types of fundus cameras and composite images. Method. The study included 491 ultra-wide-field fundus ophthalmoscopy and optical coherence tomography angiography (OCTA) images that passed an image-quality review and were graded as no apparent DR (NDR; 169 images), mild nonproliferative DR (NPDR; 76 images), moderate NPDR (54 images), severe NPDR (90 images), and proliferative DR (PDR; 102 images) by three retinal experts by the International Clinical Diabetic Retinopathy Severity Scale. The findings of tests 1 and 2 to identify no apparent diabetic retinopathy (NDR) and PDR, respectively, were then assessed. For each verification, Optos, OCTA, and Optos OCTA imaging scans with DCNN were performed. Result. The Optos, OCTA, and Optos OCTA imaging test results for comparison between NDR and DR showed mean areas under the curve (AUC) of 0.79, 0.883, and 0.847; sensitivity rates of 80.9%, 83.9%, and 78.6%; and specificity rates of 55%, 71.6%, and 69.8%, respectively. Meanwhile, the Optos, OCTA, and Optos OCTA imaging test results for comparison between NDR and PDR showed mean AUC of 0.981, 0.928, and 0.964; sensitivity rates of 90.2%, 74.5%, and 80.4%; and specificity rates of 97%, 97%, and 96.4%, respectively. Conclusion. The combination of Optos and OCTA imaging with DCNN could detect DR at desirable levels of accuracy and may be useful in clinical practice and retinal screening. Although the combination of multiple imaging techniques might overcome their individual weaknesses and provide comprehensive imaging, artificial intelligence in classifying multimodal images has not always produced accurate results.

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2

Aragón, V., Á. García, R. Amaro, C. Martínez, F. Sarmiento, J. Cabo, and M. Sempere. "OPTOS communications: A high-performance solution." Microwave and Optical Technology Letters 54, no. 4 (February 16, 2012): 943–46. http://dx.doi.org/10.1002/mop.26717.

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3

Ghahghaei, Saeideh, and Laura Walker. "SKERI-Optos: A Graphical User Interface to Map Scotoma and PRL with the Optos OCT/SLO." Journal of Vision 16, no. 4 (February 12, 2016): 40. http://dx.doi.org/10.1167/16.4.41.

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4

Lau, Chap-Kay Kendra, and Gloria Wu. "Smartphone Camera to Image the Retina for Primary Care MDs and Diabetologists." Journal of the Endocrine Society 5, Supplement_1 (May 1, 2021): A401. http://dx.doi.org/10.1210/jendso/bvab048.816.

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Abstract Background: Imaging is an important tool for diagnosis of hypertension and diabetes for all physicians. In the US, 300 million smartphones were purchased in 2019. Purpose: A smartphone-based ophthalmoscope for fundus imaging was compared to an office based retina camera to evaluate the average time spent on each device. Methods: Inclusion criteria: Patients with 20/20-20/50 vision, informed consent was obtained. D-Eye/iphone digital direct ophthalmoscope (Padova, Italy) was used on the dilated and undilated eyes of patients, video recorded to attain an image of the optic nerve and internally timed in the iPhone. Optos (Marlborough, MA) was then used to take retinal images of both dilated and undilated eyes of patients for comparison. The start time and end time was recorded from the timestamp of the 1st and last image taken on Optos, then the difference between both timestamps was calculated to obtain time spent on Optos. Results: For dilated patients (n=12, 24 eyes), the average time taken to obtain a clear video of both eyes using D-Eye was 28.08 seconds. The average time to take images of both eyes using Optos was 1.83 minutes. For undilated patients (n=10, 20 eyes), the average time of a clear video of both eyes using D-Eye was 29.8 seconds. The average time to take clear images of both eyes using Optos was 1.2 minutes. Conclusion: The portable D-Eye attachment may be useful at primary care settings, eye MD offices, bedside, ER, and wheelchair patients for evaluation and diagnosis. The D-Eye attachment for the smartphone is useful for imaging both dilated and undilated eyes. We look forward to future studies of the D-Eye for more complex retinal images.

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Rivas Abalo, J., J. Martínez Oter, I. Arruego Rodríguez, A. Martín-Ortega Rico, J. R. de Mingo Martín, J. J. Jiménez Martín, B. Martín Vodopivec, S. Rodríguez Bustabad, and H. Guerrero Padrón. "OWLS as platform technology in OPTOS satellite." CEAS Space Journal 9, no. 4 (November 11, 2017): 543–54. http://dx.doi.org/10.1007/s12567-017-0178-0.

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6

Matsui, Yoshitsugu, Atsushi Ichio, Asako Sugawara, Eriko Uchiyama, Hitomi Suimon, Hisashi Matsubara, Masahiko Sugimoto, Kengo Ikesugi, and Mineo Kondo. "Comparisons of Effective Fields of Two Ultra-Widefield Ophthalmoscopes, Optos 200Tx and Clarus 500." BioMed Research International 2019 (December 5, 2019): 1–7. http://dx.doi.org/10.1155/2019/7436293.

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Purpose. To compare the effective fields of the Optos 200Tx® and Clarus 500™, two ultra-widefield ophthalmoscopes, based on their ability to image branches of retinal vessel in the four retinal quadrants. Methods. Ninety retinal images from 90 patients with various eye diseases were studied. All patients had undergone 200° retinal imaging to obtain a single image of Optos (O) and the montage of two images of the Clarus (C). The highest number of traceable vessel branches in the four retinal quadrants was determined by two masked raters. An image was classified as “O > C” when the number of identifiable branch was greater in the Optos than the Clarus, as “O = C” when the number was equal and as “O < C” when the number was fewer in the Optos than the Clarus. Results. The appearance probability of “O > C” was significantly higher at the upper temporal quadrant than “O < C” (p<0.01 for both raters). In contrast, the appearance probability of “O < C” was significantly higher at the lower nasal quadrant than “O > C” (p<0.01 for both raters). There were no significant differences in the appearance probability between “O > C” and “O < C” at the other two retinal quadrants (p>0.50 for both raters). Conclusions. These results demonstrate that the effective field of views was different between the two devices at different retina quadrants. Further studies are needed to clarify possible factors such as artifacts by the eyelashes, differences in the depth of focus, motion of the device, and different locations of the images on the effective field of views.

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Fierz, Fabienne C., and Chetan K. Patel. "Optos ultra-widefield imaging in intubated pediatric patients." Journal of American Association for Pediatric Ophthalmology and Strabismus 22, no. 4 (August 2018): e54. http://dx.doi.org/10.1016/j.jaapos.2018.07.197.

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8

Duisdieker, Viola, Monika Fleckenstein, Katharina M. Zilkens, Julia S. Steinberg, Frank G. Holz, and Steffen Schmitz-Valckenberg. "Long-Term Follow-Up of Fundus Autofluorescence Imaging Using Wide-Field Scanning Laser Ophthalmoscopy." Ophthalmologica 234, no. 4 (2015): 218–26. http://dx.doi.org/10.1159/000439358.

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Aim: To evaluate the variation of peripheral alterations in different retinal diseases over a period of >3 years by using wide-field fundus autofluorescence (FAF) scanning laser ophthalmoscopy (SLO). Methods: A total of 26 eyes from 13 patients (median age 66 years, range 19-80) with age-related macular degeneration and other retinal degenerations were examined. In 2009, the Optos P200CAF prototype and from 2012 onwards, the Optos 200Tx (Optos plc, Scotland) were used for wide-field FAF SLO (excitation 532 nm). Results: The area involvement in outer retinal pathological alterations, such as atrophy and mottling of the retinal pigment epithelium far beyond the vascular arcades, was readily and better visualized within one image frame using wide-field FAF as compared to pseudocolor SLO of the same device. Over time, progression of existing and the development of de novo peripheral lesions were recorded with a concomitant enlargement of central lesions. In two cases (unilateral paravenous pigmented choroidal atrophy and suspected phenocopy of retinal dystrophy), no longitudinal changes of the topographic distribution of peripheral FAF intensities were noted. Conclusions: Wide-field FAF SLO allows the mapping of dynamic changes at the outer retina far beyond the vascular arcades. While its ability to detect and monitor these changes appears to be better than that of pseudocolor imaging, wide-field FAF SLO may not only be helpful to assess more widespread retinal dysfunction, but may also be useful for longitudinal assessments in natural history studies and interventional clinical trials.

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Nagasawa, Toshihiko, Hitoshi Tabuchi, Hiroki Masumoto, Hiroki Enno, Masanori Niki, Hideharu Ohsugi, and Yoshinori Mitamura. "Accuracy of deep learning, a machine learning technology, using ultra-wide-field fundus ophthalmoscopy for detecting idiopathic macular holes." PeerJ 6 (October 22, 2018): e5696. http://dx.doi.org/10.7717/peerj.5696.

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We aimed to investigate the detection of idiopathic macular holes (MHs) using ultra-wide-field fundus images (Optos) with deep learning, which is a machine learning technology. The study included 910 Optos color images (715 normal images, 195 MH images). Of these 910 images, 637 were learning images (501 normal images, 136 MH images) and 273 were test images (214 normal images and 59 MH images). We conducted training with a deep convolutional neural network (CNN) using the images and constructed a deep-learning model. The CNN exhibited high sensitivity of 100% (95% confidence interval CI [93.5–100%]) and high specificity of 99.5% (95% CI [97.1–99.9%]). The area under the curve was 0.9993 (95% CI [0.9993–0.9994]). Our findings suggest that MHs could be diagnosed using an approach involving wide angle camera images and deep learning.

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10

Sisk, Robert A., Prashant K. Parekh, and Christopher D. Riemann. "Fingerprint Macula Artifact on Optos Fundus Imaging in Nystagmus." Ophthalmology 127, no. 1 (January 2020): 96. http://dx.doi.org/10.1016/j.ophtha.2019.09.020.

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11

Tucher, Nico, Johannes Eisenlohr, Peter Kiefel, Oliver Höhn, Hubert Hauser, Marius Peters, Claas Müller, Jan Christoph Goldschmidt, and Benedikt Bläsi. "3D optical simulation formalism OPTOS for textured silicon solar cells." Optics Express 23, no. 24 (November 25, 2015): A1720. http://dx.doi.org/10.1364/oe.23.0a1720.

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12

Garranzo, Daniel, Armonía Núñez, Hugo Laguna, Tomás Belenguer, and Eduardo de Miguel. "APIS: the miniaturized Earth observation camera on-board OPTOS CubeSat." Journal of Applied Remote Sensing 13, no. 03 (May 10, 2019): 1. http://dx.doi.org/10.1117/1.jrs.13.032502.

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13

Martín-Ortega, Alberto, Santiago Rodríguez, José R. de Mingo, Sergio Ibarmia, Joaquín Rivas, Sergio López-Buedo, Celia López-Ongil, and Marta Portela-García. "Data Analysis and Results of the Radiation-Tolerant Collaborative Computer On-Board OPTOS CubeSat." International Journal of Aerospace Engineering 2019 (February 12, 2019): 1–11. http://dx.doi.org/10.1155/2019/1425892.

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The current evolution of the space missions demands to increase the computing capacities of the on-board computer while reducing its power consumption. This requirement evolves faster than the ability of the manufacturers to develop better space-qualified processors. To meet the strong requirements, the National Institute of Aerospace Technology has developed a distributed on-board computer based on commercial off-the-shelf (COTS). This computer, named OPTOS, provides enhanced computational capacities with respect to what computers of other small satellites typically provide. To maintain the reliability needed to perform typical critical activities such as real-time maintenance or current surveillance, authors have conceived a set of collaborative hardening techniques, taking advantage of the distributed architecture of the OPTOS On-Board Computer. The 3-year mission data analysis shows the feasibility of the collaborative hardening techniques implemented, despite using SEU sensitive devices. The authors describe the processes and tools used to analyse the data and clearly expose the functional errors found at unit level, while the system remains unfaulty and reliable thanks to the collaborative techniques.

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14

Sherman, Jerome, Sanjeev Nath, and Michelle Battaglia. "Poster 53 - Can the OPTOS Teach Clinicians to be Better Ophthalmoscopists?" Optometry - Journal of the American Optometric Association 76, no. 6 (June 2005): 383–84. http://dx.doi.org/10.1016/s1529-1839(05)70380-8.

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15

Sherman, Jerome, Sarah MacIver, Marc Sherman, and Samantha Slotnick. "Comparison of RNFL Assessment With the Optos® P200 and 200Dx." Optometry - Journal of the American Optometric Association 82, no. 6 (June 2011): 363. http://dx.doi.org/10.1016/j.optm.2011.04.041.

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Shah, Sumit P., Atul Jain, Robert E. Coffee, and Tara A. McCannel. "Optos Panoramic 200MA™ Ultrawide-Field Imaging of Peripheral RPE Adenoma." Seminars in Ophthalmology 24, no. 1 (January 2009): 37–39. http://dx.doi.org/10.1080/08820530802520210.

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17

Arnold, Andrew W., Andrew M. Eller, Kyle A. Smith, Robin L. Grendahl, R. Kevin Winkle, and Robert W. Arnold. "Direct OPTOS Nerve Size Determination of Prevalent Optic Nerve Hypoplasia in Alaska." Clinical Ophthalmology Volume 14 (February 2020): 491–99. http://dx.doi.org/10.2147/opth.s242548.

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18

Fung, Timothy H. M., Janine Abramson, Shalini Ojha, and Roger Holden. "Systemic Effects of Optos versus Indirect Ophthalmoscopy for Retinopathy of Prematurity Screening." Ophthalmology 125, no. 11 (November 2018): 1829–32. http://dx.doi.org/10.1016/j.ophtha.2018.06.001.

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19

Sherman, Jerome, Hanish Patel, Sanjeev Nath, Juliana Boneta, Sharanjit Burmy, and Dalia Layliev. "Correlation Between Optos Ultra Widefield Imaging and Traditional Diagnostic Methods in Glaucoma." Optometry - Journal of the American Optometric Association 80, no. 6 (June 2009): 302–3. http://dx.doi.org/10.1016/j.optm.2009.04.038.

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20

Win, Peter H., and Tara A. Young. "Optos Panoramic200A™ Fluorescein Angiography for Proliferative Diabetic Retinopathy with Asteroid Hyalosis." Seminars in Ophthalmology 22, no. 2 (January 2007): 67–69. http://dx.doi.org/10.1080/08820530701331644.

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21

MACKENZIE, PAUL J., MATT RUSSELL, PATRICK E. MA, CAROLYN M. ISBISTER, and DAVID A. L. MABERLEY. "SENSITIVITY AND SPECIFICITY OF THE OPTOS OPTOMAP FOR DETECTING PERIPHERAL RETINAL LESIONS." Retina 27, no. 8 (October 2007): 1119–24. http://dx.doi.org/10.1097/iae.0b013e3180592b5c.

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22

Higaki, Masahiko, Miho Nozaki, Munenori Yoshida, and Yuichiro Ogura. "Less Expansion of Short-Pulse Laser Scars in Panretinal Photocoagulation for Diabetic Retinopathy." Journal of Ophthalmology 2018 (2018): 1–8. http://dx.doi.org/10.1155/2018/9371895.

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Purpose. To compare the expansion rates of laser photocoagulation scars between the conventional laser and short-pulse laser using fundus autofluorescence (FAF). Methods. Retrospective chart review. Conventional laser was performed on 6 eyes of 6 patients, and short-pulse laser was performed on 11 eyes of 8 patients with diabetic retinopathy. FAF images were obtained by Optos® 200Tx (Optos, Dunfermline, Scotland, UK) at 1, 3, 6, and 12 months after treatment. The average area of 20 photocoagulation scars was measured by using ImageJ software. The expansion rates were calculated from the proportion of the averaged area against the optic disc area. Regression of retinopathy and central macular thickness were also evaluated. Results. The expansion rates of the conventional laser scars compared with the size at 1 month after treatment were 1.12 ± 0.08 (3 M), 1.27 ± 0.12 (6 M), and 1.39 ± 0.11 (12 M). The expansion rates of the short-pulse laser scars were 1.04 ± 0.05 (3 M), 1.09 ± 0.04 (6 M), and 1.13 ± 0.05 (12 M). The expansion rates of the short-pulse laser were significantly lower than those of the conventional laser (p<0.01). Conclusion. FAF images were useful to evaluate the changes in the photocoagulation scar sizes. The scars with the short-pulse laser showed lower expansion rates than those of the conventional laser.

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Inoue, Maiko, Akihiko Yanagawa, Shin Yamane, Akira Arakawa, Yuko Kawai, and Kazuaki Kadonosono. "Wide-Field Fundus Imaging Using the Optos Optomap and a Disposable Eyelid Speculum." JAMA Ophthalmology 131, no. 2 (February 1, 2013): 226. http://dx.doi.org/10.1001/jamaophthalmol.2013.750.

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Muqit, Mahiul M. K., George R. Marcellino, David B. Henson, Lorna B. Young, Niall Patton, Stephen J. Charles, George S. Turner, and Paulo E. Stanga. "Optos-guided pattern scan laser (Pascal)-targeted retinal photocoagulation in proliferative diabetic retinopathy." Acta Ophthalmologica 91, no. 3 (December 16, 2011): 251–58. http://dx.doi.org/10.1111/j.1755-3768.2011.02307.x.

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Tambova, Emre, Huseyin Gursoy, Hikmet Basmak, Erdogan Yasar, Mustafa Deger Bilgec, and N. Dilruba Koseoglu. "Evaluation of Posterior Segment Diseases Using Optos and Telemedicine Application in Eskisehir Region." International Journal of Research Studies in Medical and Health Sciences 5, no. 2 (2020): 1–5. http://dx.doi.org/10.22259/ijrsmhs.0502001.

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Psomiadi, Angeliki, Gertrud Haas, Michael Edlinger, Nikolaos E. Bechrakis, and Georgios Blatsios. "Ultra-wide-field imaging of choroidal melanoma before and after proton beam radiation therapy." European Journal of Ophthalmology 30, no. 6 (August 30, 2019): 1397–402. http://dx.doi.org/10.1177/1120672119873210.

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Objective: To evaluate the imaging characteristics of choroidal melanoma before and after proton beam radiotherapy via Optos® ultra-wide-field scanning laser ophthalmoscopy. Methods: Retrospective, descriptive study of choroidal melanoma patients treated with proton beam radiotherapy. All patients underwent full clinical evaluation, including best-corrected visual acuity, ultrasound examination and ultra-wide-field scanning laser ophthalmoscopy imaging in the pseudo-colour (red and green channel) as well as auto-fluorescence mode. Tumours were classified and evaluated according to their location, size, presence of subretinal fluid, drusen, orange pigment and reflectance intensity in ultra-wide-field scanning laser ophthalmoscopy. Tumour sonographic (basal diameter, height) and ultra-wide-field scanning laser ophthalmoscopy imaging dimensions (maximal diameter) were documented. Results: A total of 39 eyes (38 patients) were followed for 24 months (range 6–48 months). Mean best-corrected visual acuity dropped from 20/40 to 20/63 after proton beam radiotherapy. There was no change in the imaging tumour characteristics during follow-up. Subretinal fluid changes were better detected in the autofluorescence compared to pseudo-colour mode. Mean tumour diameter did not significantly change in the ultra-wide-field scanning laser ophthalmoscopy although it did so in the ultrasound. No patient showed local tumour recurrence. Conclusion: The ultra-wide-field scanning laser ophthalmoscopy imaging characteristics of choroidal melanoma in the Optos® system do not significantly change after proton beam radiotherapy after a mean follow-up of 2 years.

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Sodhi, Simrat K., John Golding, Carmelina Trimboli, and Netan Choudhry. "Feasibility of peripheral OCT imaging using a novel integrated SLO ultra-widefield imaging swept-source OCT device." International Ophthalmology 41, no. 8 (April 8, 2021): 2805–15. http://dx.doi.org/10.1007/s10792-021-01837-7.

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Abstract Purpose To describe the feasibility of peripheral OCT imaging in retinal diseases using a novel full-field device. Methods A total of 134 consecutive eyes were referred and imaged on the Optos Silverstone swept-source OCT (SS-OCT) (Optos PLC; Dunfermline, UK). Scanning laser ophthalmoscope (SLO) images and the associated SS-OCT images were obtained in the posterior pole, mid-periphery or far periphery based on the nature of the referral and on new areas of interest observed in the optomap images at the time of imaging. Results A total of 134 eyes (96 patients) were enrolled in the study. One hundred and twenty-five eyes (91 patients) with 38 retinal pathologies were prospectively assessed and 9 eyes (5 patients) were excluded due to incomplete image acquisition. The average age of the subjects was 54 years (range 21–92 years). Thirty-nine out of 125 eyes (31%) had macular pathologies. Eighty-six out of 125 eyes (69%) had peripheral only pathologies, an area which cannot be visualized by standard OCT devices with a 50 degree field-of-view. Conclusions The ability to capture peripheral pathologies using an integrated SLO-UWF imaging with full-field swept-source provided high-grade anatomical insight that confirmed the medical and surgical management in a majority of cases. Its use in the mid- and far periphery provides a holistic clinical picture, which can potentially aid in the understanding of various retinal pathologies.

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Kovacs, Kyle D., M. Abdallah Mahrous, Luis Gonzalez, Benjamin E. Botsford, Tamara L. Lenis, Michael C. Ryan, Anton Orlin, Thanos D. Papakostas, Donald J. D’Amico, and Szilárd Kiss. "Feasibility and Clinical Utility of Ultra-Widefield–Navigated Swept-Source Optical Coherence Tomography Imaging." Journal of VitreoRetinal Diseases 5, no. 5 (March 19, 2021): 396–404. http://dx.doi.org/10.1177/2474126421997335.

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Purpose: This work aims to evaluate the clinical utility and feasibility of a novel scanning laser ophthalmoscope-based navigated ultra-widefield swept-source optical coherence tomography (UWF SS-OCT) imaging system. Methods: A retrospective, single-center, consecutive case series evaluated patients between September 2019 and October 2020 with UWF SS-OCT (modified Optos P200TxE, Optos PLC) as part of routine retinal care. The logistics of image acquisition, interpretability of images captured, nature of the peripheral abnormality, and clinical utility in management decisions were recorded. Results: Eighty-two eyes from 72 patients were included. Patients were aged 59.4 ± 17.1 years (range, 8-87 years). During imaging, 4.4 series of images were obtained in 4.1 minutes, with 86.4% of the image series deemed to be diagnostic of the peripheral pathology on blinded image review. The most common pathologic findings were chorioretinal scars (18 eyes). In 31 (38%) eyes, these images were meaningful in supporting clinical decision-making with definitive findings. Diagnoses imaged included retinal detachment combined with retinoschisis, retinal hole with overlying vitreous traction and subretinal fluid, vitreous inflammation overlying a peripheral scar, Coats disease, and peripheral retinal traction in sickle cell retinopathy. Conclusions: Navigated UWF SS-OCT imaging was clinically practical and provided high-quality characterization of peripheral retinal lesions for all eyes. Images directly contributed to management plans, including laser, injection or surgical treatment, for a clinically meaningful set of patients (38%). Future studies are needed to further assess the value of this imaging modality and its role in diagnosing, monitoring, and treating peripheral lesions.

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Li, Shuang, Jing-Jing Wang, Hong-Yang Li, Wei Wang, Meng Tian, Xu-Qiang Lang, and Kang Wang. "Performance evaluation of two fundus oculi angiographic imaging system: Optos 200Tx and Heidelberg Spectralis." Experimental and Therapeutic Medicine 21, no. 1 (November 5, 2020): 1. http://dx.doi.org/10.3892/etm.2020.9451.

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Kato, Yukihito, Masaru Oguchi, Akeno Tamaoki, Norihiko Yoshida, Tatsushi Kaga, and Kazuo Ichikawa. "Performance of Fundus Photography Using the Ultra-Widefield Scanning Laser Ophthalmoscope Optos 200Tx^|^trade;." JAPANESE ORTHOPTIC JOURNAL 41 (2012): 207–12. http://dx.doi.org/10.4263/jorthoptic.041f122.

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Meyer, Carsten H., and Sandeep Saxena. "Non-mydriatic imaging of a giant retinal tear with the Optos Optomap Panoramic 200MA." Clinical & Experimental Ophthalmology 38, no. 4 (February 26, 2010): 427. http://dx.doi.org/10.1111/j.1442-9071.2010.02260.x.

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Shah, Sumit P., Atul Jain, Irena Tsui, and Tara A. McCannel. "Optos Optomap Panoramic 200MA™ Imaging of a Serous Choroidal Detachment Responsive to Furosemide." Seminars in Ophthalmology 24, no. 1 (January 2009): 40–42. http://dx.doi.org/10.1080/08820530802520236.

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Assil, Kerry K., and V. Nicholas Batra. "The Role of Ultra-widefield Retinal Imaging as a Standard Assessment Tool in the Cataract Practice." US Ophthalmic Review 10, no. 01 (2017): 31. http://dx.doi.org/10.17925/usor.2017.10.01.31.

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Comprehensive evaluation of retinal health prior to and following cataract surgery is critical to supporting optimal outcomes. In addition to the importance of identifying retinal pathology that may prevent or delay cataract surgery, continuous advances in refractive intraocular lens technology and cataract surgical technique, coupled with increasingly high expectations regarding visual outcomes among younger patients, make the consideration of long-term quality of vision paramount in the cataract assessment. Optos® ultrawidefield retinal imaging supports this clinical objective by providing imaging standardization in a streamlined, patient-friendly exam process, supporting robust documentation that facilitates mapping of disease progression, and offering potential economic advantages in a resourceconstrained environment.

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Cicinelli, Maria Vittoria, Alessandro Marchese, Francesco Bandello, and Giulio Maria Modorati. "3D WrapTM Ultra-Widefield Reconstruction in Stereotactic Radiosurgery for Choroidal Melanoma." Ocular Oncology and Pathology 6, no. 1 (June 12, 2019): 20–24. http://dx.doi.org/10.1159/000500312.

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Choroidal melanoma (CM) is the most commonly diagnosed primary intraocular malignancy in adults. Gamma knife radiosurgery (GKR) has demonstrated reliable results in the treatment of CM, but it is limited by the risk of radiation-induced ocular complications. To optimize the dose of radiation focused on the tumor, and limit side effects, the eye should be properly immobilized before treatment. A recently released ultra-widefield imaging instrument (Optomap California; Optos, Dunfermline, Scotland, UK) allows for an interactive three-dimensional (3D) virtual reconstruction of the globe, called 3D WrapTM. The authors share their experience with this rapid, reliable, and relatively easy support in planning globe positioning before GKR treatment.

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Martín-Ortega, Alberto, Marta Portela-García, José R. de Mingo, Santiago Rodríguez, Joaquín Rivas, Sergio López-Buedo, and Celia López-Ongil. "Early SEU sensitivity assessment for collaborative hardening techniques: A case study of OPTOS processing architecture." Microelectronics Reliability 95 (April 2019): 36–47. http://dx.doi.org/10.1016/j.microrel.2019.02.009.

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Byberg, Stine, Dorte Vistisen, Lars Diaz, Morten H. Charles, Javad Nouri Hajari, Marianne Valerius, Ellen Juul, Marit E. Jørgensen, and Henrik Lund‐Andersen. "Optos wide‐field imaging versus conventional camera imaging in Danish patients with type 2 diabetes." Acta Ophthalmologica 97, no. 8 (April 15, 2019): 815–20. http://dx.doi.org/10.1111/aos.14118.

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Tucher, Nico, Johannes Eisenlohr, Habtamu Gebrewold, Peter Kiefel, Oliver Höhn, Hubert Hauser, Jan Christoph Goldschmidt, and Benedikt Bläsi. "Optical simulation of photovoltaic modules with multiple textured interfaces using the matrix-based formalism OPTOS." Optics Express 24, no. 14 (June 9, 2016): A1083. http://dx.doi.org/10.1364/oe.24.0a1083.

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Tucher, Nico, Björn Müller, Peter Jakob, Johannes Eisenlohr, Oliver Höhn, Hubert Hauser, Jan Christoph Goldschmidt, Martin Hermle, and Benedikt Bläsi. "Optical performance of the honeycomb texture – a cell and module level analysis using the OPTOS formalism." Solar Energy Materials and Solar Cells 173 (December 2017): 66–71. http://dx.doi.org/10.1016/j.solmat.2017.06.004.

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Fierz, Fabienne, and Chetan K. Patel. "Retinopathy of Prematurity Status: Invisible with Indirect Ophthalmoscopy but Established with Optos Ultrawide-Field Retinal Imaging." Ophthalmology 126, no. 1 (January 2019): 86. http://dx.doi.org/10.1016/j.ophtha.2018.11.008.

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Jain, Atul, Sumit P. Shah, Irena Tsui, and Tara A. McCannel. "The Value of Optos Panoramic 200MA™ Imaging for the Monitoring of Large Suspicious Choroidal Lesions." Seminars in Ophthalmology 24, no. 1 (January 2009): 43–44. http://dx.doi.org/10.1080/08820530802520384.

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Fung, Timothy H. M., Imran H. Yusuf, Lewis M. Smith, Jon Brett, Laura Weston, and C. K. Patel. "Outpatient Ultra wide-field intravenous fundus fluorescein angiography in infants using the Optos P200MA scanning laser ophthalmoscope." British Journal of Ophthalmology 98, no. 3 (December 12, 2013): 302–4. http://dx.doi.org/10.1136/bjophthalmol-2013-304450.

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Sherman, Jerome, Sanjeev Nath, Sarah MacIver, March Sherman, Juliana E. Boneta, Dan Epshtein, Jeremy Whitney, and Samantha Slotnick. "Does Serial Optos® Panoramic Imaging Improve Differential Diagnosis of Glaucomatous RNFL Defects From Physiological RNFL “Slits”?" Optometry - Journal of the American Optometric Association 82, no. 6 (June 2011): 362–63. http://dx.doi.org/10.1016/j.optm.2011.04.039.

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Patel, C. K., T. H. M. Fung, M. M. K. Muqit, D. J. Mordant, J. Brett, L. Smith, and E. Adams. "Non-contact ultra-widefield imaging of retinopathy of prematurity using the Optos dual wavelength scanning laser ophthalmoscope." Eye 27, no. 5 (March 22, 2013): 589–96. http://dx.doi.org/10.1038/eye.2013.45.

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Mauro-Herrera, Margarita, John Chiang, Bojana Radojevic, and Lea D. Bennett. "Functional Evaluation of Splicing for Variants of Uncertain Significance in Patients with Inherited Retinal Diseases." Genes 12, no. 7 (June 29, 2021): 993. http://dx.doi.org/10.3390/genes12070993.

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Inherited retinal diseases (IRD) comprise a heterogeneous set of clinical and genetic disorders that lead to blindness. Given the emerging opportunities in precision medicine and gene therapy, it has become increasingly important to determine whether DNA variants with uncertain significance (VUS) are responsible for patients’ IRD. This research was performed to assess the functional consequence of six VUS identified in patients with IRD. Clinical assessments included an ophthalmic examination, best-corrected visual acuity, and kinetic perimetry. Imaging was acquired with the Optos ultra-widefield camera and spectral domain optical coherence tomography (SD-OCT). Genetic testing was performed by Molecular Vision Laboratories. VUS that were predicted to alter splicing were analyzed with a minigene assay, which revealed that VUS in the genes OPA1, CNGB1, and CLUAP1 altered spicing mechanisms. Due to emerging gene and cell therapies, these results expand the genotype-phenotype correlations for patients diagnosed with an IRD.

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Özdemir, Özdemir, and Chetan Kantibhai Patel. "Binocular Indirect Ophthalmoscopy Complements Non-contact Wide-field Imaging with Optos to Treat a Baby Outside ETROP Guidelines." Turkish Journal of Ophthalmology 48, no. 5 (October 1, 2018): 250–53. http://dx.doi.org/10.4274/tjo.90699.

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Tripathy, Koushik, Rohan Chawla, Bhushan Ratansingh Wadekar, Pradeep Venkatesh, and Yog Raj Sharma. "Evaluation of rhegmatogenous retinal detachments using Optos ultrawide field fundus fluorescein angiography and comparison with ETDRS 7 field overlay." Journal of Current Ophthalmology 30, no. 3 (September 2018): 263–67. http://dx.doi.org/10.1016/j.joco.2018.06.006.

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Buckle, Miranda, and Chetan K. Patel. "Re: Fung et al.: Systemic effects of optos versus indirect ophthalmoscopy for retinopathy of prematurity screening (Ophthalmology. 2018;125:1829-1832)." Ophthalmology 126, no. 3 (March 2019): e20. http://dx.doi.org/10.1016/j.ophtha.2018.10.024.

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Dolar-Szczasny, Joanna, Anna Święch-Zubilewicz, and Jerzy Mackiewicz. "Innovation in retinal diseases – ultra-widefield imaging." Polish Journal of Public Health 125, no. 1 (March 1, 2015): 14–16. http://dx.doi.org/10.1515/pjph-2015-0014.

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Abstract The understanding of retinal disease has evolved rapidly with a growing number of clinical evidence supplied by ultrawidefield retinal imaging. Optos 200Tx ultra-widefield retinal imaging system uses a scanning laser ophthalmoscope, as well as an ellipsoid mirror. This creates a possibility of making a virtual focal point inside the eye and, in turn, enables the system to simultaneously make a single capture of the central retina and periphery. This system offers multimodal ultra-widefield imaging, including color photographs, fundus autofluorescence images, red-free images and fluorescein angiography (FA), allowing visualization of the retinal circulation. For color photographs, green and red lasers are used simultaneously to allow visualization of retinal substructures from the sensory retina and retinal pigment epithelium to the choroid. In our clinic ultra-widefield fluorescein angiography has became an elegant diagnostic imaging modality that has improved our ability to diagnose and plan treatment strategies. In the future widefield imaging will probably be coupled with OCT (optical coherence tomography) option to better evaluate retinal pathologies in the periphery.

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Sachdev, Amun, Magdalena Edington, Rupal Morjaria, and Ngaihang Chong. "Comparing Macular Thickness Measurements in Patients with Diabetic Macular Edema with the Optos Spectral OCT/SLO and Heidelberg Spectralis HRA + OCT." Vision 1, no. 1 (April 12, 2016): 2. http://dx.doi.org/10.3390/vision1010002.

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Logroño Wiese, Pablo Eduardo, Frank Seeber, Anne-Sophie Endres, Claudia Brockmann, and Uwe Pleyer. "Screening for common eye diseases in the elderly with Optos ultra-wide-field scanning laser ophthalmoscopy: a pilot study with focus on ocular toxoplasmosis." International Ophthalmology 41, no. 5 (March 16, 2021): 1573–84. http://dx.doi.org/10.1007/s10792-020-01683-z.

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Abstract Purpose Studies on the occurrence of ocular toxoplasmosis (OT) in a general population are rare. Therefore, we conducted this pilot study to assess whether a nonmydriatic ultra-wide-field (UWF) scanning laser ophthalmoscope (SLO) is suitable for a simple, rapid screening procedure. Methods The population of this cross-sectional study was randomly recruited from a cohort of hospital-based patients in an urban geriatric hospital. Ophthalmologic evaluation was performed on 201 eyes from 101 participants through nonmydriatic UWF-SLO (Optos Daytona) and assessed for suspicious lesions and other relevant ocular findings. All images were evaluated by two independent examiners. Individuals who presented lesions with a morphological appearance suggestive of OT underwent fundoscopy and serological analysis of Toxoplasma gondii-specific antibodies. Results The mean age of the study group was 76 years, and 63 (62%) were female. Despite many health restrictions, the SLO examination was carried out easily in this geriatric population. Three participants presented findings by SLO suspicious for T. gondii-related injury. Further clinical examination and serological investigation confirmed the diagnosis, with funduscopic evaluation and positive T. gondii ELISA testing. In addition, a high rate of arterial hypertension and dyslipidemias within the cohort led to a high incidence of vascular changes and age-related fundus findings. Conclusion In our study, we confirm that UWF-SLO technology is helpful in the rapid detection of peripheral retinal injuries in elderly patients such as OT and may be used as a routine screening tool.

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