Academic literature on the topic 'Optical Biosensing'

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Journal articles on the topic "Optical Biosensing"

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Scheggi, A. M., and A. G. Mignani. "Optical fiber biosensing." Optics News 15, no. 11 (November 1, 1989): 28. http://dx.doi.org/10.1364/on.15.11.000028.

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Kim, Youngsun, John Gonzales, and Yuebing Zheng. "Optical Biosensing: Sensitivity‐Enhancing Strategies in Optical Biosensing (Small 4/2021)." Small 17, no. 4 (January 2021): 2170016. http://dx.doi.org/10.1002/smll.202170016.

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Banciu, Roberta Maria, Nimet Numan, and Alina Vasilescu. "Optical biosensing of lysozyme." Journal of Molecular Structure 1250 (February 2022): 131639. http://dx.doi.org/10.1016/j.molstruc.2021.131639.

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Melvin, Tracy. "Optical biosensing: future possibilities." Expert Review of Ophthalmology 2, no. 6 (December 2007): 883–87. http://dx.doi.org/10.1586/17469899.2.6.883.

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Bally, Marta, Martin Halter, Janos Vörös, and H. Michelle Grandin. "Optical microarray biosensing techniques." Surface and Interface Analysis 38, no. 11 (2006): 1442–58. http://dx.doi.org/10.1002/sia.2375.

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Barrios, Carlos, Víctor Canalejas-Tejero, Sonia Herranz, Javier Urraca, María Moreno-Bondi, Miquel Avella-Oliver, Ángel Maquieira, and Rosa Puchades. "Aluminum Nanoholes for Optical Biosensing." Biosensors 5, no. 3 (July 9, 2015): 417–31. http://dx.doi.org/10.3390/bios5030417.

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Chiavaioli, Francesco, Francesco Baldini, Sara Tombelli, Cosimo Trono, and Ambra Giannetti. "Biosensing with optical fiber gratings." Nanophotonics 6, no. 4 (June 7, 2017): 663–79. http://dx.doi.org/10.1515/nanoph-2016-0178.

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AbstractOptical fiber gratings (OFGs), especially long-period gratings (LPGs) and etched or tilted fiber Bragg gratings (FBGs), are playing an increasing role in the chemical and biochemical sensing based on the measurement of a surface refractive index (RI) change through a label-free configuration. In these devices, the electric field evanescent wave at the fiber/surrounding medium interface changes its optical properties (i.e. intensity and wavelength) as a result of the RI variation due to the interaction between a biological recognition layer deposited over the fiber and the analyte under investigation. The use of OFG-based technology platforms takes the advantages of optical fiber peculiarities, which are hardly offered by the other sensing systems, such as compactness, lightness, high compatibility with optoelectronic devices (both sources and detectors), and multiplexing and remote measurement capability as the signal is spectrally modulated. During the last decade, the growing request in practical applications pushed the technology behind the OFG-based sensors over its limits by means of the deposition of thin film overlays, nanocoatings, and nanostructures, in general. Here, we review efforts toward utilizing these nanomaterials as coatings for high-performance and low-detection limit devices. Moreover, we review the recent development in OFG-based biosensing and identify some of the key challenges for practical applications. While high-performance metrics are starting to be achieved experimentally, there are still open questions pertaining to an effective and reliable detection of small molecules, possibly up to single molecule, sensing in vivo and multi-target detection using OFG-based technology platforms.
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Sharma, Shubhanshi, Rashmi Kumari, Shailendra K. Varshney, and Basudev Lahiri. "Optical biosensing with electromagnetic nanostructures." Reviews in Physics 5 (November 2020): 100044. http://dx.doi.org/10.1016/j.revip.2020.100044.

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Yang, Xiao, Congcong Li, Peifeng Li, and Qinrui Fu. "Ratiometric optical probes for biosensing." Theranostics 13, no. 8 (2023): 2632–56. http://dx.doi.org/10.7150/thno.82323.

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Maniya, Nalin H. "Recent Advances in Porous Silicon Based Optical Biosensors." REVIEWS ON ADVANCED MATERIALS SCIENCE 53, no. 1 (January 1, 2018): 49–73. http://dx.doi.org/10.1515/rams-2018-0004.

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Abstract PSi structures have unique physical and optical properties, which are being exploited for a numerous biomedical applications including biosensing, bioimaging, tissue engineering, and drug delivery. Different PSi optical structures can be fabricated to improve the sensitivity of the optical measurements. A very high surface area per volume of PSi can be used for the higher loading of target analytes in a small sensor area, which helps in increasing sensitivity and allows the miniaturization of biosensor. The specificity of PSi biosensor to the target analyte can be inferred by immobilizing the corresponding bioreceptor such as DNA, enzyme, or antibody via different conjugation chemistries. Finally, PSi is biocompatible material that offers additional advantage in comparison to other sensing platforms for in vivo implantable biosensing applications. This paper reviews fabrication, surface modification, biofunctionalization, and optical biosensing applications of PSi structures with special emphasis on in vivo and PSi photonic particles biosensing.
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Dissertations / Theses on the topic "Optical Biosensing"

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King, Branden Joel. "Tapered Optical Fiber Platform for Biosensing Applications." University of Dayton / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=dayton1398708775.

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Blyth, David John. "Optical biosensing using sol-gel technology." Thesis, University of East Anglia, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338063.

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Greenhalgh, Andrew Bryce. "Tapered polymer optical fibres for biosensing." Thesis, Manchester Metropolitan University, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.423074.

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D'Imperio, Luke A. "Biosensing-inspired Nanostructures:." Thesis, Boston College, 2019. http://hdl.handle.net/2345/bc-ir:108627.

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Thesis advisor: Michael J. Naughton
Nanoscale biosensing devices improve and enable detection mechanisms by taking advantage of properties inherent to nanoscale structures. This thesis primarily describes the development, characterization and application of two such nanoscale structures. Namely, these two biosensing devices discussed herein are (1) an extended-core coaxial nanogap electrode array, the ‘ECC’ and (2) a plasmonic resonance optical filter array, the ‘plasmonic halo’. For the former project, I discuss the materials and processing considerations that were involved in the making of the ECC device, including the nanoscale fabrication, experimental apparatuses, and the chemical and biological materials involved. I summarize the ECC sensitivity that was superior to those of conventional detection methods and proof-of-concept bio-functionalization of the sensing device. For the latter project, I discuss the path of designing a biosensing device based on the plasmonic properties observed in the plasmonic halo, including the plasmonic structures, materials, fabrication, experimental equipment, and the biological materials and protocols
Thesis (PhD) — Boston College, 2019
Submitted to: Boston College. Graduate School of Arts and Sciences
Discipline: Physics
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Jamali, Abdul Aleem [Verfasser]. "Optical Antennas for Biosensing Applications / Abdul Aleem Jamali." Kassel : Universitätsbibliothek Kassel, 2015. http://d-nb.info/1073856577/34.

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Krasovska, Inese. "Optical Properties of Silicon Nanopillar Arrays for Biosensing." Thesis, KTH, Skolan för informations- och kommunikationsteknik (ICT), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-175760.

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Biosensing is currently a growing research field which is relevant for different applications, for instance in health care. Sensitive and cheap biosensors are required, preferably as simple as possible in their working principle. In this work Si nanopillar structures have been fabricated and used to show the sensing principle by both depositing oxide layers with different thicknesses and by using the biotinstreptavidin model system. Si nanopillars were fabricated by two different surface patterning methods – colloidal lithography and nanoimprint lithography (obtained from a commercial source). For colloidal lithography, a modified drop-coating technique as well as a spin-coating technique is used to make self-assembled silicon dioxide (SiO2) monolayers. It is shown that SiO2 particles with sizes of 0.5 μm and 1.0 μm form even monolayers across areas of ~2 mm2 (sufficient for optical measurements) after optimizing the spin-coating parameters. Particle size reduction is done by using reactive ion etching (RIE) and nanopillars with heights of 1.0 μm to 1.5 μm are etched by inductively coupled plasma RIE (ICP RIE). Spectrally resolved reflectance from the nanopillar arrays, often show distinct reflectance peaks. Depending on the nanopillar geometry, the wavelength position of the reflectance peaks can be sensitive to changes in the refractive index at the nanopillar surface, for example by attached bio-molecules or by a thin dielectric (e.g. silicon-di-oxide) surface layer. In order to simulate the effect of a surface-bio layer on the optical properties of the nanopillar arrays, silicon-di-oxide coated Si nanopillars were investigated experimentally and theoretically. The simulated reflectance spectra, obtained by Lumerical FDTD, show that the spectral shifts of the reflectance peaks grow linearly with the layer thickness. The deposition of the oxide layers is done by plasma-enhanced chemical vapor deposition (PECVD). While this technique is reliable for planar surfaces, pillar structures showed both a much reduced side-wall oxide thickness as well as oxide pile-up on the top of the pillars. However, by thermally driven material reflow it was possible, though not completely, to redistribute the piled-up oxide from the pillar top to the sidewalls. Reflectance from Si nanopillar structures was investigated primarily using UV-vis-NIR spectrophotometer. However, ellipsometry and Fourier transform infrared spectroscopy were also used for comparison. The experimental results of the oxide layer deposition on Si nanopillars show a maximum spectral shift of 4.6 nm per every 10 nm of deposited SiO2. 3 Moreover, the obtained linear behavior of the spectral shift with oxide thickness is similar to the simulated one. In order to use the biotin-streptavidin model system to demonstrate the sensing principle with Si nanopillar structures, a surface functionalization protocol was optimized on the planar SiO2 coated Si surface. As it turns out, both an anhydrous environment and water presence during the surface silanization prior to biotinilation are acceptable and lead to similar results. Further work is necessary for effective surface functionalization of nanopillars. However, preliminary investigations of (test structures) nanopillar arrays surface functionalized by biotinstreptavidin showed spectral shifts. The sensitivity was not sufficient to perform a full assay. Optimization of the nanopillar geometry for high surface sensitivity as well as improvement in the surface functionalization process are required to produce a sensitive biosensor.
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Chung, Chun Lam Cathy K. S. "Optical biosensing of iron(III) in oceanic waters." Thesis, University of East Anglia, 2004. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.405393.

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Barreau, Stephanie. "Biosensing with sol-gel-immobilised proteins." Thesis, Loughborough University, 1999. https://dspace.lboro.ac.uk/2134/27275.

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Low temperature-processed, porous sol-gel glasses represent a new class of materials for the immobilisation of biomolecules. If used to entrap biological recognition elements, these transparent and chemically inert glasses offer a new approach in the development of optical biosensors.
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Oleksiy, Krupin. "Biosensing Using Long-Range Surface Plasmon-Polariton Waveguides." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/34210.

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Specific detection of biological matter is one of the key elements in a wide range of modern fields such as food industry, medicine, environmental and pharmaceutical industries. Generally, current common methods of detection (e.g. ELISA) involve molecular labelling, requirements for well-trained personnel and lengthy experimental procedures such as bacteria culture. All of the above issues result in high costs for biological analysis, and consequently, high costs for medical service, therapeutic drugs and various food products. Biosensors, on the other hand, can provide quick and cheap solutions to these problems. The field of optical biosensors is dominated by the method of surface plasmon resonance, which so far has attracted a lot of attention in the pharmaceutical industry. Investigation of long-range surface plasmon-polariton waveguides as an application for biosensing is still very novel, and most of it exists in the venue of theoretical discussions and modelling. The objective of this thesis is to demonstrate the capability of the novel optical biosensor based on plasmonic waveguides to selectively detect various biological entities in solutions. The experiments were conducted on photolithographically fabricated sensors consisting of straight gold waveguides embedded in low-refractive index fluoropolymer CYTOP and a microfluidic channel. As a proof-of-concept, a demonstration of basic sensing experiments such as detection of change in refractive index of bulk solution and non-specific adsorption of bovine serum albumin is provided. Further investigation of the sensor capabilities involved specific detection of human red blood cells and leukemia markers. Red blood cell detection was based on ABO blood grouping and included the estimation of limit of detection and signal-to-noise ratio for single cell detection. Finally, a clinically relevant problem of B-cell leukemia marker detection was targeted. The sensor demonstrated the ability to detect the relative abundance of similar proteins (immunoglobulin kappa and lambda) in a complex fluid (human serum). In addition, an experimental study on the optimization of the sensor for sensitivity was conducted.
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Nemzer, Louis R. "Oxidoreductase Immobilization in Reprecipitated Polyaniline Nanostructures for Optical Biosensing Applications." The Ohio State University, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=osu1265751296.

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Books on the topic "Optical Biosensing"

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Vollmer, Frank, and Deshui Yu. Optical Whispering Gallery Modes for Biosensing. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-06858-4.

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Vollmer, Frank, and Deshui Yu. Optical Whispering Gallery Modes for Biosensing. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-60235-2.

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Rao, Govind. Optical Sensor Systems in Biotechnology. Berlin, Heidelberg: Springer-Verlag Berlin Heidelberg, 2010.

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Calif.) Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications (Conference) (13th 2013 San Francisco. Optical fibers and sensors for medical diagnostics and treatment applications XIII: 2-3 February 2013, San Francisco, California, United States. Edited by Gannot, Israel, editor of compilation, SPIE (Society), and SPIE Photonics West (Conference) (2013 : San Francisco, Calif.). Bellingham, Wash: SPIE, 2013.

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Gannot, Israel. Optical fibers, sensors, and devices for biomedical diagnostics and treatment XI: 22-23 January 2011 San Francisco, California, United States. Bellingham: sponsored and published by SPIE, 2011.

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Israel, Gannot, and Society of Photo-optical Instrumentation Engineers., eds. Optical fibers and sensors for medical applications V: 22-23, 25 January 2005, San Jose, California, USA. Bellingham, Wash., USA: SPIE, 2005.

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Israel, Gannot, and Society of Photo-optical Instrumentation Engineers., eds. Optical fibers and sensors for medical applications IV: 24-25 January 2004, San Jose, California, USA. Bellingham, Wash., USA: SPIE, 2004.

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Francisco, Calif ). Optical Diagnostics and Sensing (Conference) (13th 2013 San. Optical diagnostics and sensing XIII: Toward point-of-care diagnostics, 6 February 2013, San Francisco, California, United States. Bellingham, Washington: SPIE, 2013.

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Gannot, Israel. Optical fibers and sensors for medical diagnostics and treatment applications X: 23-24 January 2010, San Francisco, California, United States. Edited by SPIE (Society). Bellingham, Wash: SPIE, 2010.

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Israel, Gannot, and Society of Photo-optical Instrumentation Engineers., eds. Optical fibers and sensors for medical diagnostics and treatment applications VII: 20-21 January 2007, San Jose, California, USA. Bellingham, Wash: SPIE, 2007.

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Book chapters on the topic "Optical Biosensing"

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Walt, David R. "Optical Biosensing." In Biosensing, 31–43. Dordrecht: Springer Netherlands, 2006. http://dx.doi.org/10.1007/1-4020-4058-x_2.

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Schuster, Tobias, René Landgraf, Andreas Finn, and Michael Mertig. "Biosensing with Optical Waveguides." In Bio and Nano Packaging Techniques for Electron Devices, 557–79. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-28522-6_28.

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Tarsa, Peter B., and Kevin K. Lehmann. "CAVITY RING-DOWN BIOSENSING." In Optical Biosensors, 403–18. Elsevier, 2008. http://dx.doi.org/10.1016/b978-044453125-4.50011-5.

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Martín-Palma, Raúl J. "Optical Biosensors." In Field Guide to Optical Biosensing. SPIE, 2021. http://dx.doi.org/10.1117/3.2575468.ch6.

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Martín-Palma, Raúl J. "Fluorescence-Based Biosensing." In Field Guide to Optical Biosensing. SPIE, 2021. http://dx.doi.org/10.1117/3.2575468.ch46.

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Martín-Palma, Raúl J. "Phosphorescence-Based Biosensing." In Field Guide to Optical Biosensing. SPIE, 2021. http://dx.doi.org/10.1117/3.2575468.ch48.

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Martín-Palma, Raúl J. "Biosensing Using Ellipsometry." In Field Guide to Optical Biosensing. SPIE, 2021. http://dx.doi.org/10.1117/3.2575468.ch44.

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Martín-Palma, Raúl J. "Phase-Sensitive Biosensing." In Field Guide to Optical Biosensing. SPIE, 2021. http://dx.doi.org/10.1117/3.2575468.ch58.

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Martín-Palma, Raúl J. "Evanescent Wave Biosensing." In Field Guide to Optical Biosensing. SPIE, 2021. http://dx.doi.org/10.1117/3.2575468.ch52.

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Martín-Palma, Raúl J. "Optical Phase Difference and Optical Path Difference." In Field Guide to Optical Biosensing. SPIE, 2021. http://dx.doi.org/10.1117/3.2575468.ch28.

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Conference papers on the topic "Optical Biosensing"

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Blair, Steve, and Yan Chen. "Biosensing with optical microcavities." In BiOS 2001 The International Symposium on Biomedical Optics, edited by Raymond P. Mariella, Jr. and Dan V. Nicolau. SPIE, 2001. http://dx.doi.org/10.1117/12.427963.

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Vollmer, Frank. "Advances in Single Molecule Biosensing." In Optical Sensors. Washington, D.C.: OSA, 2015. http://dx.doi.org/10.1364/sensors.2015.set4c.2.

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Ushenko, Alexander, V. G. Zhytaryuk, M. I. Sidor, A. V. Motrich, O. V. Pavliukovich, O. Ya Wulchulyak, I. V. Soltys, and N. Pavliukovich. "Diffuse tomography of optical anisotropy of tumors of the uterus wall." In Biosensing and Nanomedicine XI, edited by Hooman Mohseni, Massoud H. Agahi, and Manijeh Razeghi. SPIE, 2018. http://dx.doi.org/10.1117/12.2320529.

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Cojocaru, Ivan, Jing-Wei Fan, Joe Becker, Ilya V. Fedotov, Masfer H. Alkahtani, Abdulrahman Alajlan, Sean Blakley, et al. "All-optical high resolution thermometry with color centers in diamond (Conference Presentation)." In Biosensing and Nanomedicine XI, edited by Hooman Mohseni, Massoud H. Agahi, and Manijeh Razeghi. SPIE, 2018. http://dx.doi.org/10.1117/12.2320316.

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Dubolazov, Olexander V., O. Olar, L. Pidkamin, Alexander Arkhelyuk, Artem Motrich, O. Petrochak, Viktor Bachynskiy, O. Litvinenko, and S. Foglinskiy. "Methods and systems of diffuse tomography of optical anisotropy of biological layers." In Biosensing and Nanomedicine XII, edited by Hooman Mohseni and Massoud H. Agahi. SPIE, 2019. http://dx.doi.org/10.1117/12.2529184.

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Canva, Michael T. "Plasmonics for biosensing (Conference Presentation)." In Optical Sensors 2023, edited by Robert A. Lieberman, Francesco Baldini, and Jiri Homola. SPIE, 2023. http://dx.doi.org/10.1117/12.2671748.

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El-Haddad, Mohamed T., Ivan Bozic, Joseph D. Malone, Jianwei D. Li, Amber M. Arquitola, Shriji N. Patel, Karen M. Joos, and Yuankai K. Tao. "Multimodal ophthalmic imaging using spectrally encoded scanning laser ophthalmoscopy and optical coherence tomography." In Biosensing and Nanomedicine X, edited by Hooman Mohseni, Massoud H. Agahi, and Manijeh Razeghi. SPIE, 2017. http://dx.doi.org/10.1117/12.2275552.

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Canales, Andres, Seongjun Park, Chi Lu, Yoel Fink, and Polina O. Anikeeva. "Electronic, optical, and chemical interrogation of neural circuits with multifunctional fibers (Conference Presentation)." In Biosensing and Nanomedicine X, edited by Hooman Mohseni, Massoud H. Agahi, and Manijeh Razeghi. SPIE, 2017. http://dx.doi.org/10.1117/12.2276770.

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Quan, Qimin. "Biosensing with Photonic and Plasmonic Nanocavities." In Optical Sensors. Washington, D.C.: OSA, 2015. http://dx.doi.org/10.1364/sensors.2015.sew1b.1.

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Beliaev, L. Yu, P. G. Stounbjerg, G. Finco, A. I. Bunea, R. Malureanu, L. R. Lindvold, O. Takayama, P. E. Andersen, and A. V. Lavrinenko. "Conventional vs. pedestal high-contrast grating for biosensing." In Optical Sensors. Washington, D.C.: Optica Publishing Group, 2022. http://dx.doi.org/10.1364/sensors.2022.stu5c.4.

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We present a comparative study of novel pedestal and conventional high-contrast grating (HCG) structures for biosensing applications. The pedestal grating demonstrates superior performance both in bulk refractive index (BRIS) and surface sensing.
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