Journal articles on the topic 'Opioid Receptors Signaling'
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Gomes, Ivone, Salvador Sierra, Lindsay Lueptow, Achla Gupta, Shawn Gouty, Elyssa B. Margolis, Brian M. Cox, and Lakshmi A. Devi. "Biased signaling by endogenous opioid peptides." Proceedings of the National Academy of Sciences 117, no. 21 (May 11, 2020): 11820–28. http://dx.doi.org/10.1073/pnas.2000712117.
Full textAl-Hasani, Ream, and Michael R. Bruchas. "Molecular Mechanisms of Opioid Receptor-dependent Signaling and Behavior." Anesthesiology 115, no. 6 (December 1, 2011): 1363–81. http://dx.doi.org/10.1097/aln.0b013e318238bba6.
Full textScherer, Paul C., Nicholas W. Zaccor, Neil M. Neumann, Chirag Vasavda, Roxanne Barrow, Andrew J. Ewald, Feng Rao, Charlotte J. Sumner, and Solomon H. Snyder. "TRPV1 is a physiological regulator of μ-opioid receptors." Proceedings of the National Academy of Sciences 114, no. 51 (December 4, 2017): 13561–66. http://dx.doi.org/10.1073/pnas.1717005114.
Full textGutstein, Howard B., Elizabeth A. Rubie, Alfred Mansour, Huda Akil, and James R. Woodgett. "Opioid Effects on Mitogen-activated Protein Kinase Signaling Cascades." Anesthesiology 87, no. 5 (November 1, 1997): 1118–26. http://dx.doi.org/10.1097/00000542-199711000-00016.
Full textWilliams, John T., MacDonald J. Christie, and Olivier Manzoni. "Cellular and Synaptic Adaptations Mediating Opioid Dependence." Physiological Reviews 81, no. 1 (January 1, 2001): 299–343. http://dx.doi.org/10.1152/physrev.2001.81.1.299.
Full textLešnik, Samo, Éva Bertalan, Urban Bren, and Ana-Nicoleta Bondar. "Opioid Receptors and Protonation-Coupled Binding of Opioid Drugs." International Journal of Molecular Sciences 22, no. 24 (December 12, 2021): 13353. http://dx.doi.org/10.3390/ijms222413353.
Full textBolte, Craig, Gilbert Newman, and Jo El J. Schultz. "Hypertensive state, independent of hypertrophy, exhibits an attenuated decrease in systolic function on cardiac κ-opioid receptor stimulation." American Journal of Physiology-Heart and Circulatory Physiology 296, no. 4 (April 2009): H967—H975. http://dx.doi.org/10.1152/ajpheart.00909.2008.
Full textGALLAGHER, SHANNON K., JULIA N. ANGLEN, JUSTIN M. MOWER, and JOZSEF VIGH. "Dopaminergic amacrine cells express opioid receptors in the mouse retina." Visual Neuroscience 29, no. 3 (April 3, 2012): 203–9. http://dx.doi.org/10.1017/s0952523812000156.
Full textGuda, Rahul S., Katherine E. Odegaard, Chengxi Tan, Victoria L. Schaal, Sowmya V. Yelamanchili, and Gurudutt Pendyala. "Integrated Systems Analysis of Mixed Neuroglial Cultures Proteome Post Oxycodone Exposure." International Journal of Molecular Sciences 22, no. 12 (June 15, 2021): 6421. http://dx.doi.org/10.3390/ijms22126421.
Full textRocchi, Giulio, Bruno Sterlini, Samuele Tardito, Matilde Inglese, Anna Corradi, Gilberto Filaci, Mario Amore, Paola Magioncalda, and Matteo Martino. "Opioidergic System and Functional Architecture of Intrinsic Brain Activity: Implications for Psychiatric Disorders." Neuroscientist 26, no. 4 (March 5, 2020): 343–58. http://dx.doi.org/10.1177/1073858420902360.
Full textOzdemir, Ercan. "The Role of the Cannabinoid System in Opioid Analgesia and Tolerance." Mini-Reviews in Medicinal Chemistry 20, no. 10 (May 27, 2020): 875–85. http://dx.doi.org/10.2174/1389557520666200313120835.
Full textViscusi, Eugene R. "Improving the therapeutic window of conventional opioids: novel differential signaling modulators." Regional Anesthesia & Pain Medicine 44, no. 1 (January 2019): 32–37. http://dx.doi.org/10.1136/rapm-2018-000010.
Full textBedini, Andrea, Elisabetta Cuna, Monica Baiula, and Santi Spampinato. "Quantitative Systems Pharmacology and Biased Agonism at Opioid Receptors: A Potential Avenue for Improved Analgesics." International Journal of Molecular Sciences 23, no. 9 (May 4, 2022): 5114. http://dx.doi.org/10.3390/ijms23095114.
Full textHeagy, W., M. A. Shipp, and R. W. Finberg. "Opioid receptor agonists and Ca2+ modulation in human B cell lines." Journal of Immunology 149, no. 12 (December 15, 1992): 4074–81. http://dx.doi.org/10.4049/jimmunol.149.12.4074.
Full textCaputi, Francesca, Laura Rullo, Serena Stamatakos, Sanzio Candeletti, and Patrizia Romualdi. "Interplay between the Endogenous Opioid System and Proteasome Complex: Beyond Signaling." International Journal of Molecular Sciences 20, no. 6 (March 21, 2019): 1441. http://dx.doi.org/10.3390/ijms20061441.
Full textChe, Tao, and Bryan L. Roth. "Structural Insights Accelerate the Discovery of Opioid Alternatives." Annual Review of Biochemistry 90, no. 1 (June 20, 2021): 739–61. http://dx.doi.org/10.1146/annurev-biochem-061620-044044.
Full textCleymaet, Allison M., Casey-Tyler Berezin, and Jozsef Vigh. "Endogenous Opioid Signaling in the Mouse Retina Modulates Pupillary Light Reflex." International Journal of Molecular Sciences 22, no. 2 (January 8, 2021): 554. http://dx.doi.org/10.3390/ijms22020554.
Full textCleymaet, Allison M., Casey-Tyler Berezin, and Jozsef Vigh. "Endogenous Opioid Signaling in the Mouse Retina Modulates Pupillary Light Reflex." International Journal of Molecular Sciences 22, no. 2 (January 8, 2021): 554. http://dx.doi.org/10.3390/ijms22020554.
Full textDerouiche, Lyes, Florian Pierre, Stéphane Doridot, Stéphane Ory, and Dominique Massotte. "Heteromerization of Endogenous Mu and Delta Opioid Receptors Induces Ligand-Selective Co-Targeting to Lysosomes." Molecules 25, no. 19 (September 30, 2020): 4493. http://dx.doi.org/10.3390/molecules25194493.
Full textSadee, Wolfgang, and John C. McKew. "Ligand-Free Signaling of G-Protein-Coupled Receptors: Relevance to μ Opioid Receptors in Analgesia and Addiction." Molecules 27, no. 18 (September 8, 2022): 5826. http://dx.doi.org/10.3390/molecules27185826.
Full textOuyang, Handong, Shue Liu, Weian Zeng, Roy C. Levitt, Keith A. Candiotti, and Shuanglin Hao. "An Emerging New Paradigm in Opioid Withdrawal: A Critical Role for Glia-Neuron Signaling in the Periaqueductal Gray." Scientific World Journal 2012 (2012): 1–9. http://dx.doi.org/10.1100/2012/940613.
Full textCumming, Paul, János Marton, Tuomas O. Lilius, Dag Erlend Olberg, and Axel Rominger. "A Survey of Molecular Imaging of Opioid Receptors." Molecules 24, no. 22 (November 19, 2019): 4190. http://dx.doi.org/10.3390/molecules24224190.
Full textMiyano, Kanako, Yuki Yoshida, Shigeto Hirayama, Hideki Takahashi, Haruka Ono, Yoshiyuki Meguro, Sei Manabe, et al. "Oxytocin Is a Positive Allosteric Modulator of κ-Opioid Receptors but Not δ-Opioid Receptors in the G Protein Signaling Pathway." Cells 10, no. 10 (October 4, 2021): 2651. http://dx.doi.org/10.3390/cells10102651.
Full textCorkrum, Michelle, Patrick E. Rothwell, Mark J. Thomas, Paulo Kofuji, and Alfonso Araque. "Opioid-Mediated Astrocyte–Neuron Signaling in the Nucleus Accumbens." Cells 8, no. 6 (June 14, 2019): 586. http://dx.doi.org/10.3390/cells8060586.
Full textWebster, Lynn, and William K. Schmidt. "Dilemma of Addiction and Respiratory Depression in the Treatment of Pain: A Prototypical Endomorphin as a New Approach." Pain Medicine 21, no. 5 (June 5, 2019): 992–1004. http://dx.doi.org/10.1093/pm/pnz122.
Full textMazahery, Claire, Braulio Llorens, Anna Peczak, Saba Valadkhan, and Alan D. Levine. "Opioid-induced protein coding and noncoding transcriptome of human CD8+ T cells reveals opioid receptor subclass specific responses." Journal of Immunology 204, no. 1_Supplement (May 1, 2020): 77.13. http://dx.doi.org/10.4049/jimmunol.204.supp.77.13.
Full textCorder, Gregory, Daniel C. Castro, Michael R. Bruchas, and Grégory Scherrer. "Endogenous and Exogenous Opioids in Pain." Annual Review of Neuroscience 41, no. 1 (July 8, 2018): 453–73. http://dx.doi.org/10.1146/annurev-neuro-080317-061522.
Full textSternini, Catia. "III. μ-Opioid receptors in the enteric nervous system." American Journal of Physiology-Gastrointestinal and Liver Physiology 281, no. 1 (July 1, 2001): G8—G15. http://dx.doi.org/10.1152/ajpgi.2001.281.1.g8.
Full textOkuyama, Youta, Hisayo Jin, Hiroshi Kokubun, and Tomohiko Aoe. "Pharmacological Chaperones Attenuate the Development of Opioid Tolerance." International Journal of Molecular Sciences 21, no. 20 (October 13, 2020): 7536. http://dx.doi.org/10.3390/ijms21207536.
Full textGillis, Alexander, Arisbel B. Gondin, Andrea Kliewer, Julie Sanchez, Herman D. Lim, Claudia Alamein, Preeti Manandhar, et al. "Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists." Science Signaling 13, no. 625 (March 31, 2020): eaaz3140. http://dx.doi.org/10.1126/scisignal.aaz3140.
Full textMeqbil, Yazan J., and Richard M. van Rijn. "Opportunities and Challenges for In Silico Drug Discovery at Delta Opioid Receptors." Pharmaceuticals 15, no. 7 (July 15, 2022): 873. http://dx.doi.org/10.3390/ph15070873.
Full textMazahery, Claire, Saba Valadkhan, and Alan D. Levine. "Signaling from individual Opioid Receptors differentially modulates the functional and phenotypic potential of resting and activated human CD8+ T cells." Journal of Immunology 202, no. 1_Supplement (May 1, 2019): 60.8. http://dx.doi.org/10.4049/jimmunol.202.supp.60.8.
Full textMoyano, Jairo, and Luisa Aguirre. "Opioids in the immune system: from experimental studies to clinical practice." Revista da Associação Médica Brasileira 65, no. 2 (February 2019): 262–69. http://dx.doi.org/10.1590/1806-9282.65.2.262.
Full textLevac, B. "Oligomerization of opioid receptors: generation of novel signaling units." Current Opinion in Pharmacology 2, no. 1 (February 1, 2002): 76–81. http://dx.doi.org/10.1016/s1471-4892(02)00124-8.
Full textSharp, Burt M. "Multiple opioid receptors on immune cells modulate intracellular signaling." Brain, Behavior, and Immunity 20, no. 1 (January 2006): 9–14. http://dx.doi.org/10.1016/j.bbi.2005.02.002.
Full textCosta, Ana Rita, Marília Sousa, Steven P. Wilson, Carlos Reguenga, Armando Teixeira-Pinto, Isaura Tavares, and Isabel Martins. "Shift of µ-opioid Receptor Signaling in the Dorsal Reticular Nucleus Is Implicated in Morphine-induced Hyperalgesia in Male Rats." Anesthesiology 133, no. 3 (June 17, 2020): 628–44. http://dx.doi.org/10.1097/aln.0000000000003412.
Full textPanneerselvam, Mathivadhani, Yasuo M. Tsutsumi, Jacqueline A. Bonds, Yousuke T. Horikawa, Michelle Saldana, Nancy D. Dalton, Brian P. Head, Piyush M. Patel, David M. Roth, and Hemal H. Patel. "Dark chocolate receptors: epicatechin-induced cardiac protection is dependent on δ-opioid receptor stimulation." American Journal of Physiology-Heart and Circulatory Physiology 299, no. 5 (November 2010): H1604—H1609. http://dx.doi.org/10.1152/ajpheart.00073.2010.
Full textGutstein, Howard B., Jennifer L. Thome, Jeffrey L. Fine, Stanley J. Watson, and Huda Akil. "Pattern of c-fos mRNA induction in rat brain by acute morphine." Canadian Journal of Physiology and Pharmacology 76, no. 3 (March 1, 1998): 294–303. http://dx.doi.org/10.1139/y98-027.
Full textMelkes, Barbora, Vendula Markova, Lucie Hejnova, and Jiri Novotny. "β-Arrestin 2 and ERK1/2 Are Important Mediators Engaged in Close Cooperation between TRPV1 and µ-Opioid Receptors in the Plasma Membrane." International Journal of Molecular Sciences 21, no. 13 (June 29, 2020): 4626. http://dx.doi.org/10.3390/ijms21134626.
Full textMizobuchi, Yusuke, Kanako Miyano, Sei Manabe, Eiko Uezono, Akane Komatsu, Yui Kuroda, Miki Nonaka, et al. "Ketamine Improves Desensitization of µ-Opioid Receptors Induced by Repeated Treatment with Fentanyl but Not with Morphine." Biomolecules 12, no. 3 (March 10, 2022): 426. http://dx.doi.org/10.3390/biom12030426.
Full textde Corde-Skurska, Anna, Pawel Krzascik, Anna Lesniak, Mariusz Sacharczuk, Lukasz Nagraba, and Magdalena Bujalska-Zadrozny. "Disulfiram Abrogates Morphine Tolerance—A Possible Role of µ-Opioid Receptor-Related G-Protein Activation in the Striatum." International Journal of Molecular Sciences 22, no. 8 (April 14, 2021): 4057. http://dx.doi.org/10.3390/ijms22084057.
Full textHerman, Melissa A., Richard A. Gillis, Stefano Vicini, Kenneth L. Dretchen, and Niaz Sahibzada. "Tonic GABAA receptor conductance in medial subnucleus of the tractus solitarius neurons is inhibited by activation of μ-opioid receptors." Journal of Neurophysiology 107, no. 3 (February 2012): 1022–31. http://dx.doi.org/10.1152/jn.00853.2011.
Full textDiCello, Jesse J., Pradeep Rajasekhar, Emily M. Eriksson, Ayame Saito, Arisbel B. Gondin, Nicholas A. Veldhuis, Meritxell Canals, Simona E. Carbone, and Daniel P. Poole. "Clathrin and GRK2/3 inhibitors block δ-opioid receptor internalization in myenteric neurons and inhibit neuromuscular transmission in the mouse colon." American Journal of Physiology-Gastrointestinal and Liver Physiology 317, no. 2 (August 1, 2019): G79—G89. http://dx.doi.org/10.1152/ajpgi.00085.2019.
Full textJóźwiak, Krzysztof, and Anita Płazińska. "Structural Insights into Ligand—Receptor Interactions Involved in Biased Agonism of G-Protein Coupled Receptors." Molecules 26, no. 4 (February 6, 2021): 851. http://dx.doi.org/10.3390/molecules26040851.
Full textHedin, K. E., M. P. Bell, K. R. Kalli, C. J. Huntoon, B. M. Sharp, and D. J. McKean. "Delta-opioid receptors expressed by Jurkat T cells enhance IL-2 secretion by increasing AP-1 complexes and activity of the NF-AT/AP-1-binding promoter element." Journal of Immunology 159, no. 11 (December 1, 1997): 5431–40. http://dx.doi.org/10.4049/jimmunol.159.11.5431.
Full textFinnegan, Thomas F., Shao-Rui Chen, and Hui-Lin Pan. "μ Opioid Receptor Activation Inhibits GABAergic Inputs to Basolateral Amygdala Neurons Through Kv1.1/1.2 Channels." Journal of Neurophysiology 95, no. 4 (April 2006): 2032–41. http://dx.doi.org/10.1152/jn.01004.2005.
Full textShang, Yi, and Marta Filizola. "Opioid receptors: Structural and mechanistic insights into pharmacology and signaling." European Journal of Pharmacology 763 (September 2015): 206–13. http://dx.doi.org/10.1016/j.ejphar.2015.05.012.
Full textBidlack, Jean M., Maxim Khimich, Amy L. Parkhill, Sarah Sumagin, Baoyong Sun, and Christopher M. Tipton. "Opioid Receptors and Signaling on Cells from the Immune System." Journal of Neuroimmune Pharmacology 1, no. 3 (July 8, 2006): 260–69. http://dx.doi.org/10.1007/s11481-006-9026-2.
Full textBartuzi, Damian, Tomasz M. Wróbel, Agnieszka A. Kaczor, and Dariusz Matosiuk. "Tuning Down the Pain – An Overview of Allosteric Modulation of Opioid Receptors: Mechanisms of Modulation, Allosteric Sites, Modulator Syntheses." Current Topics in Medicinal Chemistry 20, no. 31 (December 3, 2020): 2852–65. http://dx.doi.org/10.2174/1568026620666200601155451.
Full textAbrimian, Anna, Tamar Kraft, and Ying-Xian Pan. "Endogenous Opioid Peptides and Alternatively Spliced Mu Opioid Receptor Seven Transmembrane Carboxyl-Terminal Variants." International Journal of Molecular Sciences 22, no. 7 (April 6, 2021): 3779. http://dx.doi.org/10.3390/ijms22073779.
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