Journal articles on the topic 'Oncogenic transformations'
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Paterno, G. D., L. L. Gillespie, M. S. Dixon, J. M. Slack, and J. K. Heath. "Mesoderm-inducing properties of INT-2 and kFGF: two oncogene-encoded growth factors related to FGF." Development 106, no. 1 (May 1, 1989): 79–83. http://dx.doi.org/10.1242/dev.106.1.79.
Full textIto, Reina E., Chitose Oneyama, and Kazuhiro Aoki. "Oncogenic mutation or overexpression of oncogenic KRAS or BRAF is not sufficient to confer oncogene addiction." PLOS ONE 16, no. 4 (April 1, 2021): e0249388. http://dx.doi.org/10.1371/journal.pone.0249388.
Full textCalabrese, Fiorella, Federica Pezzuto, Francesca Lunardi, Francesco Fortarezza, Sofia-Eleni Tzorakoleftheraki, Maria Vittoria Resi, Mariaenrica Tiné, Giulia Pasello, and Paul Hofman. "Morphologic-Molecular Transformation of Oncogene Addicted Non-Small Cell Lung Cancer." International Journal of Molecular Sciences 23, no. 8 (April 9, 2022): 4164. http://dx.doi.org/10.3390/ijms23084164.
Full textClark, SS, Y. Liang, CK Reedstrom, and SQ Wu. "Nonrandom cytogenetic changes accompany malignant progression in clonal lines abelson virus-infected lymphocytes." Blood 84, no. 12 (December 15, 1994): 4301–9. http://dx.doi.org/10.1182/blood.v84.12.4301.bloodjournal84124301.
Full textAlkharam, A. S., and D. E. Watt. "Risk Scaling Factors from Inactivation to Chromosome Aberrations, Mutations and Oncogenic Transformations in Mammalian Cells." Radiation Protection Dosimetry 70, no. 1 (April 1, 1997): 537–40. http://dx.doi.org/10.1093/oxfordjournals.rpd.a032012.
Full textJulien, Sylvie, Mirjana Radosavljevic, Nathalie Labouret, Sophie Camilleri-Broet, Frederic Davi, Martine Raphael, Thierry Martin, and Jean-Louis Pasquali. "AIDS Primary Central Nervous System Lymphoma: Molecular Analysis of the Expressed VH Genes and Possible Implications for Lymphomagenesis." Journal of Immunology 162, no. 3 (February 1, 1999): 1551–58. http://dx.doi.org/10.4049/jimmunol.162.3.1551.
Full textde Oliveira, Guilherme A. P., Elaine C. Petronilho, Murilo M. Pedrote, Mayra A. Marques, Tuane C. R. G. Vieira, Elio A. Cino, and Jerson L. Silva. "The Status of p53 Oligomeric and Aggregation States in Cancer." Biomolecules 10, no. 4 (April 4, 2020): 548. http://dx.doi.org/10.3390/biom10040548.
Full textNeitzel, Carina, Philipp Demuth, Simon Wittmann, and Jörg Fahrer. "Targeting Altered Energy Metabolism in Colorectal Cancer: Oncogenic Reprogramming, the Central Role of the TCA Cycle and Therapeutic Opportunities." Cancers 12, no. 7 (June 29, 2020): 1731. http://dx.doi.org/10.3390/cancers12071731.
Full textShrivastava, Richa, and Smrati Bhadauria. "Role of Growth Factor Signaling in Cancer." Defence Life Science Journal 1, no. 1 (June 1, 2016): 34. http://dx.doi.org/10.14429/dlsj.1.10059.
Full textAggarwal, Vaishali, Hardeep Singh Tuli, Jagjit Kaur, Diwakar Aggarwal, Gaurav Parashar, Nidarshana Chaturvedi Parashar, Samruddhi Kulkarni, et al. "Garcinol Exhibits Anti-Neoplastic Effects by Targeting Diverse Oncogenic Factors in Tumor Cells." Biomedicines 8, no. 5 (April 30, 2020): 103. http://dx.doi.org/10.3390/biomedicines8050103.
Full textMalumbres, Marcos, Ignacio Pérez De Castro, María I. Hernández, María Jiménez, Teresa Corral, and Angel Pellicer. "Cellular Response to Oncogenic Ras Involves Induction of the Cdk4 and Cdk6 Inhibitor p15INK4b." Molecular and Cellular Biology 20, no. 8 (April 15, 2000): 2915–25. http://dx.doi.org/10.1128/mcb.20.8.2915-2925.2000.
Full textNgalim, Siti Hawa, Astrid Magenau, Guillaume Le Saux, J. Justin Gooding, and Katharina Gaus. "How Do Cells Make Decisions: Engineering Micro- and Nanoenvironments for Cell Migration." Journal of Oncology 2010 (2010): 1–7. http://dx.doi.org/10.1155/2010/363106.
Full textNishizawa, Toshihiro, and Hidekazu Suzuki. "Gastric Carcinogenesis and Underlying Molecular Mechanisms:Helicobacter pyloriand Novel Targeted Therapy." BioMed Research International 2015 (2015): 1–7. http://dx.doi.org/10.1155/2015/794378.
Full textPodstawski, Przemysław, Marcin Samiec, Maria Skrzyszowska, Tomasz Szmatoła, Ewelina Semik-Gurgul, and Katarzyna Ropka-Molik. "The Induced Expression of BPV E4 Gene in Equine Adult Dermal Fibroblast Cells as a Potential Model of Skin Sarcoid-like Neoplasia." International Journal of Molecular Sciences 23, no. 4 (February 10, 2022): 1970. http://dx.doi.org/10.3390/ijms23041970.
Full textHsieh, James J., Shugaku Takeda, David Y. Chen, Todd D. Westergard, Jill K. Fisher, Jeffrey A. Rubens, Satoru Sasagawa, Jason T. Kan, Stanley J. Korsmeyer, and Emily H. Cheng. "Proteolysis of MLL Family Proteins Is Essential for Taspase1−Orchestrated Cell Cycle Progression." Blood 108, no. 11 (November 16, 2006): 769. http://dx.doi.org/10.1182/blood.v108.11.769.769.
Full textSankar, Savita, Jason M. Tanner, Russell Bell, Aashi Chaturvedi, R. Lor Randall, Mary C. Beckerle, and Stephen L. Lessnick. "A Novel Role for Keratin 17 in Coordinating Oncogenic Transformation and Cellular Adhesion in Ewing Sarcoma." Molecular and Cellular Biology 33, no. 22 (September 16, 2013): 4448–60. http://dx.doi.org/10.1128/mcb.00241-13.
Full textFarhana, Aisha, Avin Ee-Hwan Koh, Sangeetha Kothandan, Abdullah Alsrhani, Pooi Ling Mok, and Suresh Kumar Subbiah. "Treatment of HT29 Human Colorectal Cancer Cell Line with Nanocarrier-Encapsulated Camptothecin Reveals Histone Modifier Genes in the Wnt Signaling Pathway as Important Molecular Cues for Colon Cancer Targeting." International Journal of Molecular Sciences 22, no. 22 (November 13, 2021): 12286. http://dx.doi.org/10.3390/ijms222212286.
Full textGiamougiannis, Panagiotis, Pierre L. Martin-Hirsch, and Francis L. Martin. "The evolving role of MUC16 (CA125) in the transformation of ovarian cells and the progression of neoplasia." Carcinogenesis 42, no. 3 (February 20, 2021): 327–43. http://dx.doi.org/10.1093/carcin/bgab010.
Full textBorzillo, G. V., and C. J. Sherr. "Early pre-B-cell transformation induced by the v-fms oncogene in long-term mouse bone marrow cultures." Molecular and Cellular Biology 9, no. 9 (September 1989): 3973–81. http://dx.doi.org/10.1128/mcb.9.9.3973-3981.1989.
Full textBorzillo, G. V., and C. J. Sherr. "Early pre-B-cell transformation induced by the v-fms oncogene in long-term mouse bone marrow cultures." Molecular and Cellular Biology 9, no. 9 (September 1989): 3973–81. http://dx.doi.org/10.1128/mcb.9.9.3973.
Full textLiu, Yingting, Jeremy Purvis, Andrew Shih, Joshua Weinstein, Neeraj Agrawal, and Ravi Radhakrishnan. "A Multiscale Computational Approach to Dissect Early Events in the Erb Family Receptor Mediated Activation, Differential Signaling, and Relevance to Oncogenic Transformations." Annals of Biomedical Engineering 35, no. 6 (February 2, 2007): 1012–25. http://dx.doi.org/10.1007/s10439-006-9251-0.
Full textFarhana, Aisha, Avin Ee-Hwan Koh, Jia Bei Tong, Abdullah Alsrhani, Suresh Kumar Subbiah, and Pooi Ling Mok. "Nanoparticle-Encapsulated Camptothecin: Epigenetic Modulation in DNA Repair Mechanisms in Colon Cancer Cells." Molecules 26, no. 17 (September 6, 2021): 5414. http://dx.doi.org/10.3390/molecules26175414.
Full textBitler, Benjamin G., Lauren S. Fink, Zhi Wei, Jeffrey R. Peterson, and Rugang Zhang. "A High-Content Screening Assay for Small-Molecule Modulators of Oncogene-Induced Senescence." Journal of Biomolecular Screening 18, no. 9 (June 3, 2013): 1054–61. http://dx.doi.org/10.1177/1087057113491827.
Full textHarrington, M. A., F. Gonzales, and P. A. Jones. "Effect of cellular determination on oncogenic transformation by chemicals and oncogenes." Molecular and Cellular Biology 8, no. 10 (October 1988): 4322–27. http://dx.doi.org/10.1128/mcb.8.10.4322-4327.1988.
Full textHarrington, M. A., F. Gonzales, and P. A. Jones. "Effect of cellular determination on oncogenic transformation by chemicals and oncogenes." Molecular and Cellular Biology 8, no. 10 (October 1988): 4322–27. http://dx.doi.org/10.1128/mcb.8.10.4322.
Full textXu, Shihao, Cody M. Spencer, and Joshua Munger. "Transformation with Oncogenic Ras and the Simian Virus 40 T Antigens Induces Caspase-Dependent Sensitivity to Fatty Acid Biosynthetic Inhibition." Journal of Virology 89, no. 12 (April 8, 2015): 6406–17. http://dx.doi.org/10.1128/jvi.03671-14.
Full textXu, Mai, Qing Yu, Ramesh Subrahmanyam, Michael J. Difilippantonio, Thomas Ried, and Jyoti Misra Sen. "β-Catenin Expression Results in p53-Independent DNA Damage and Oncogene-Induced Senescence in Prelymphomagenic Thymocytes In Vivo." Molecular and Cellular Biology 28, no. 5 (December 26, 2007): 1713–23. http://dx.doi.org/10.1128/mcb.01360-07.
Full textMaeda, Takahiro, Robin Hobbs, Taha Merghoub, Ilhem Guernah, Arthur Zelent, Julie Teruya-Feldstein, and Pier Paolo Pandolfi. "POKEMON Is a Proto-Oncogene Which Plays a Key Role in Lymphomagenesis." Blood 104, no. 11 (November 16, 2004): 3489. http://dx.doi.org/10.1182/blood.v104.11.3489.3489.
Full textLand, H., A. C. Chen, J. P. Morgenstern, L. F. Parada, and R. A. Weinberg. "Behavior of myc and ras oncogenes in transformation of rat embryo fibroblasts." Molecular and Cellular Biology 6, no. 6 (June 1986): 1917–25. http://dx.doi.org/10.1128/mcb.6.6.1917-1925.1986.
Full textLand, H., A. C. Chen, J. P. Morgenstern, L. F. Parada, and R. A. Weinberg. "Behavior of myc and ras oncogenes in transformation of rat embryo fibroblasts." Molecular and Cellular Biology 6, no. 6 (June 1986): 1917–25. http://dx.doi.org/10.1128/mcb.6.6.1917.
Full textLy, Tony, Aki Endo, Alejandro Brenes, Marek Gierlinski, Vackar Afzal, Andrea Pawellek, and Angus I. Lamond. "Proteome-wide analysis of protein abundance and turnover remodelling during oncogenic transformation of human breast epithelial cells." Wellcome Open Research 3 (May 2, 2018): 51. http://dx.doi.org/10.12688/wellcomeopenres.14392.1.
Full textSasaki, Rumi, Mako Narisawa-Saito, Takashi Yugawa, Masatoshi Fujita, Hironori Tashiro, Hidetaka Katabuchi, and Tohru Kiyono. "Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes." Carcinogenesis 30, no. 3 (January 6, 2009): 423–31. http://dx.doi.org/10.1093/carcin/bgp007.
Full textChan, Lai N., Christian Hurtz, Huimin Geng, Franziska Auer, Zhengshan Chen, Gang Xiao, Jae-Woong Lee, Kadriye Nehir Cosgun, B. Hilda Ye, and Markus Muschen. "Ras-Driven B-Cell Transformation Targets Developmental Rewiring of Cytokine to Pre-B Cell Receptor Signaling." Blood 132, Supplement 1 (November 29, 2018): 1336. http://dx.doi.org/10.1182/blood-2018-99-115514.
Full textGarcía-Silva, Susana, and Ana Aranda. "The Thyroid Hormone Receptor Is a Suppressor of ras-Mediated Transcription, Proliferation, and Transformation." Molecular and Cellular Biology 24, no. 17 (September 1, 2004): 7514–23. http://dx.doi.org/10.1128/mcb.24.17.7514-7523.2004.
Full textDe, Pradip, Brett James Rozeboom, Jennifer Carlson Aske, and Nandini Dey. "Active RAC1 Promotes Tumorigenic Phenotypes and Therapy Resistance in Solid Tumors." Cancers 12, no. 6 (June 11, 2020): 1541. http://dx.doi.org/10.3390/cancers12061541.
Full textNtziachristos, Panagiotis, Kelly Arcipowski, Carlos Alberto Martinez, Yixing Zhu, Andrew G. Volk, Suresh Kumar, Paul M. Thomas, et al. "Therapeutic Targeting of the Histone Ubiquitination-Methylation Axis in T Cell Leukemia." Blood 128, no. 22 (December 2, 2016): 1532. http://dx.doi.org/10.1182/blood.v128.22.1532.1532.
Full textAlghisi, Elisa, Michele Malagola, Cristina Santoriello, Cristina Skert, Carla Filì, Cesare Bergonzi, Annalisa Peli, et al. "Establishing a New Zebrafish Model to Study Malignant Transformation in Myeloproliferative Disorders." Blood 118, no. 21 (November 18, 2011): 4711. http://dx.doi.org/10.1182/blood.v118.21.4711.4711.
Full textGuo, Beichu, and Jinyu Zhang. "Senescence associated inflammasome (SAI) activation promotes cancer progression (TUM4P.909)." Journal of Immunology 192, no. 1_Supplement (May 1, 2014): 138.10. http://dx.doi.org/10.4049/jimmunol.192.supp.138.10.
Full textMali, Raghuveer Singh, Peilin Ma, Li-Fan Zeng, Holly Martin, Baskar Ramdas, Yantao He, Emily Sims, et al. "Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT." Blood 120, no. 13 (September 27, 2012): 2669–78. http://dx.doi.org/10.1182/blood-2011-08-375873.
Full textKannan, Perry, and Michael A. Tainsky. "Coactivator PC4 Mediates AP-2 Transcriptional Activity and Suppresses ras-Induced Transformation Dependent on AP-2 Transcriptional Interference." Molecular and Cellular Biology 19, no. 1 (January 1, 1999): 899–908. http://dx.doi.org/10.1128/mcb.19.1.899.
Full textBose, Indrani. "Tipping the Balance: A Criticality Perspective." Entropy 24, no. 3 (March 14, 2022): 405. http://dx.doi.org/10.3390/e24030405.
Full textLadenson, P. W. "Optimal laboratory testing for diagnosis and monitoring of thyroid nodules, goiter, and thyroid cancer." Clinical Chemistry 42, no. 1 (January 1, 1996): 183–87. http://dx.doi.org/10.1093/clinchem/42.1.183.
Full textSanchez-Martin, Marta, and Adolfo Ferrando. "The NOTCH1-MYC highway toward T-cell acute lymphoblastic leukemia." Blood 129, no. 9 (March 2, 2017): 1124–33. http://dx.doi.org/10.1182/blood-2016-09-692582.
Full textLim, Jonathan K. M., Alberto Delaidelli, Sean W. Minaker, Hai-Feng Zhang, Milena Colovic, Hua Yang, Gian Luca Negri, et al. "Cystine/glutamate antiporter xCT (SLC7A11) facilitates oncogenic RAS transformation by preserving intracellular redox balance." Proceedings of the National Academy of Sciences 116, no. 19 (April 18, 2019): 9433–42. http://dx.doi.org/10.1073/pnas.1821323116.
Full textAlema, S., F. Tato, and D. Boettiger. "myc and src oncogenes have complementary effects on cell proliferation and expression of specific extracellular matrix components in definitive chondroblasts." Molecular and Cellular Biology 5, no. 3 (March 1985): 538–44. http://dx.doi.org/10.1128/mcb.5.3.538-544.1985.
Full textAlema, S., F. Tato, and D. Boettiger. "myc and src oncogenes have complementary effects on cell proliferation and expression of specific extracellular matrix components in definitive chondroblasts." Molecular and Cellular Biology 5, no. 3 (March 1985): 538–44. http://dx.doi.org/10.1128/mcb.5.3.538.
Full textSeyedmehdi, Shojaee, Zhengshan Chen, Maike Buchner, Christian Hurtz, Huimin Geng, Hilde Schjerven, Lai N. Chan, et al. "Erk and Stat5 Feedback Control Enables Pre-B Cell Transformation and Represents a Therapeutic Target in Acute Lymphoblastic Leukemia." Blood 124, no. 21 (December 6, 2014): 787. http://dx.doi.org/10.1182/blood.v124.21.787.787.
Full textMumby, M. C., and G. Walter. "Protein phosphatases and DNA tumor viruses: transformation through the back door?" Cell Regulation 2, no. 8 (August 1991): 589–98. http://dx.doi.org/10.1091/mbc.2.8.589.
Full textSulis, Maria Luisa, Teresa Palomero, Pedro J. Real, Kelly C. Barnes, Peter Aplan, Neal Copeland, Dave Utpal, et al. "Identification of Oncogenic Pathways of T-Acute Lymphoblastic Leukemia (T-ALL) through Gene Expression Profiling of Mouse Tumor Models." Blood 108, no. 11 (November 1, 2006): 2234. http://dx.doi.org/10.1182/blood.v108.11.2234.2234.
Full textPandya, Jyotsna, and Dennis M. Walling. "Oncogenic Activity of Epstein-Barr Virus Latent Membrane Protein 1 (LMP-1) Is Down-Regulated by Lytic LMP-1." Journal of Virology 80, no. 16 (August 15, 2006): 8038–46. http://dx.doi.org/10.1128/jvi.00180-06.
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