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Published: 11 March 2023

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1

Tymofieiev, Oleksii. "Journal's Award in 2018: Andrii V. Kopchak, ScD, Professor." Journal of Diagnostics and Treatment of Oral and Maxillofacial Pathology 3, no. 2 (February 28, 2019): A16. http://dx.doi.org/10.23999/j.dtomp.2019.2.6.

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Andrii V. Kopchak, Doctor of Medical Sciences (ScD), Professor serves in the Bogomolets National Medical University as: • Professor, Department of Dentistry, Institute of Postgraduate Education. • Director, Dental Medical Center. Also Dr. Kopchak does his best as a Director in the Center of Maxillofacial Surgery and Dentistry, Kyiv Regional Clinical Hospital. From 2019 Dr. Kopchak headed a Kyiv Branch of the Association of Dentists of Ukraine. With a whole editorial staff we are more than grateful for an amazing assistance to the Journal that Dr. Kopchak does not only with the inspiring articles (co-authors: Romanova and Mykhailenko), (Hresko, Chernohorskyi, and Vereshchagin) but also in his work at a position of Section Editor─Osteosynthesis of Facial Bones from the Issue 3─4, 2017. So, we feel so humbled when we gave the Journal`s honorary plaque to Professor Kopchak. But we find the next words: “For the unique skills in organization of OMS meetings, uniting and educating the new generations of surgeons sincere thanks and appreciation.”
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2

Wang, Rize, Ruohe Gao, Xin Feng, and Gangsheng Zhang. "Nacre crystal growth as a paradigm of island growth mode: Hydrophobic substrate is one of the keys to the biomineralization." Materials Express 10, no. 5 (May 1, 2020): 762–69. http://dx.doi.org/10.1166/mex.2020.1752.

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Nacre is a multilayered film material consisting of alternating layers of aragonitic tablets and organic membranes (OMs). However, at this time, no authors have discussed the growth mode of nacre from the perspective of the science of typical film materials. Here, for the first time, we focus on measuring the contact angles of the nacre growth surface (GS) using the contact angle meter. Additionally, we also investigate the GS's structure and phases using field emission scanning electron microscopy and X-ray diffractometer, respectively. We firstly found that: (1) The contact angles of the GS are always greater than 90°, with a maximum value of 113° and minimum value of 91°, indicating that the GS is hydrophobic. (2) The growth mode of GS is similar to the island growth mode (V-W) of the typical films. (3) The hydrophobicity of OMs plays an important role in the nucleation and growth of nacre. This research may provide new insights into the mechanism underlying nacre formation. In the field of thin-film, this conclusion will provide a new direction for the preparation and research of hydrophobic substrates, and a new idea for the development of thin-film technology.
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3

Mills, S. J., A. R. Kampf, R. M. Housley, G. Favreau, M. Pasero, C. Biagioni, S. Merlino, C. Berbain, and P. Orlandi. "Omsite, (Ni, Cu)2Fe3+(OH)6[Sb(OH)6], a new member of the cualstibite group from Oms, France." Mineralogical Magazine 76, no. 5 (October 2012): 1347–54. http://dx.doi.org/10.1180/minmag.2012.076.5.16.

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AbstractOmsite (IMA 2012-025) is a new mineral from the Correc d'en Llinassos, Oms, Pyrénées-Orientales Department, France. It occurs as bright yellow to amber yellow discoidal tablets, flattened on {001}, which form rosettes typically 50–100 μm in diameter. Omsite generally crystallizes on siderite without associated supergene minerals; it occurs less commonly with glaukosphaerite. Crystals have a vitreous to resinous lustre, and are transparent to translucent. Omsite is not fluorescent in either short-wave or long-wave ultraviolet light. It has an estimated hardness of 3 on the Mohs' scale, is brittle with an irregular fracture, and has one poor cleavage on {001}. The calculated density is 3.378 g cm–3. Crystals are uniaxial (–), with indices of refraction of ω = 1.728(3) and ε = 1.66(1), measured in white light. Pleochroism is ω = orange-yellow, ε = pale orange-yellow; ω > ε. The empirical formula [based on 12 (OH + Cl) p.f.u.] is (Ni1.0992+Cu0.6652+Mg0.107Fe0.0453+)Σ 1.916Fe1.0003+(Sb0.9475+As0.072Na0.029)Σ1.048OH11.967Cl0.033. Omsite crystallizes in space group P, with unit-cell parameters a = 5.3506(8), c = 19.5802(15) Å, V = 485.46(10) Å3 and Z = 2 determined by single crystal X-ray diffraction. The five strongest lines in the X-ray powder diffraction pattern [d in Å, (Irel), (hkl)] are as follows: 4.901, (100), (004); 4.575, (83), (011); 2.3539, (81), (11); 1.8079, (48), (11); 3.781, (34), (103). The crystal structure was solved to R1 = 0.0896 for 356 observed reflections [Fo>4σFo] and 0.1018 for all the 469 unique reflections. Omsite is a layered double hydroxide (LDH) mineral, with a topology consistent with members of the hydrotalcite supergroup and cualstibite group.
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4

NOGUEIRA-FILHO, Getúlio da Rocha, Cristine M. STEFANI, Márcio Z. CASATI, Celina M. NAKAI, Carla A. S. PLAZA, Francisco H. NOCITI Jr., Enilson A. SALLUM, and Sérgio de TOLEDO. "Necessidade de tratamento periodontal avaliada pelo CPITN e sua relação com a qualidade de acabamento cervical das restaurações." Pesquisa Odontológica Brasileira 15, no. 1 (March 2001): 51–55. http://dx.doi.org/10.1590/s1517-74912001000100010.

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Irregularidades do acabamento cervical de restaurações constituem fatores de retenção de placa bacteriana, dificultando o controle de placa pelos procedimentos habituais de higiene bucal, favorecendo o desenvolvimento da doença periodontal. O objetivo deste estudo foi avaliar as condições periodontais e a necessidade de tratamento em função do acabamento cervical de restaurações dentais. Foram examinados 367 dentes restaurados com classes II e V de amálgama, classe III em resina, restauração metálica fundida e próteses unitárias. Utilizando-se sonda periodontal (OMS), verificou-se a posição do término da restauração (supragengival, subgengival ou ao nível da margem gengival); a qualidade das restaurações (falta ou excesso de material restaurador) e a presença de grau 2 do CPITN. Após a análise dos dados, foi possível concluir que: 1) o término supragengival ofereceu a melhor adaptação marginal e a menor freqüência de grau 2 do CPITN; 2) a falta ou excesso de material restaurador favorecem o desenvolvimento de grau 2, independentemente do material utilizado e 3) nos términos subgengivais, foi maior a freqüência de adaptação marginal incorreta, principalmente casos de excesso de material restaurador, sendo estes casos de maior ocorrência de grau 2 do CPITN.
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5

Dohkoh, Tatsuki, Shinya Suzuki, and Masaru Miyayama. "Proton Storage Properties of Manganese Oxides with Tunnel Structures." Key Engineering Materials 566 (July 2013): 145–48. http://dx.doi.org/10.4028/www.scientific.net/kem.566.145.

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The electrochemical capacitors (ECs) have attracted a great attention as a rechargeable strage device with a high power density and high safety. An increase in specific capacity is demanded to use ECs in various applications. MnO2 are expected as electrodes of ECs because of their large oxidation state change (Mn4+ Mn2+), low cost and environmental compatibility. When all manganese ions in the MnO2 are completely reduced to Mn2+ from Mn4+ over a potential window of 1.1 V, the theoretical capacity is estimated to about 2000 Fg-1. However, the reported capacity of MnO2 electrodes are 100250 Fg-1 [1-2] for powders and around 700 Fg-1 [3] for thin films. Tunnel structured MnO2 are expected to show high capacities by utilizing high ionic mobility in the tunnel and high surface area of tunnel walls. Fig. 1 shows crystal structures of (a) Pyrolusite (Tunnel size: 1×1), (b) Hollandite (Tunnel size: 2×2) and (c) OMS-5 (Tunnel size: 2×4) and (d) MnO6 unit. In the present study, the relationship between the tunnel size and the specific capacity was investigated for those tunnel structured MnO2. In addition, Hollandite /carbon composites were synthesized to improve the electrode properties of Hollandite.
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Oscátegui Peña, Margarita Eli. "Paso 3: Hacia una educación prenatal en lactancia materna." Revista Peruana de Investigación Materno Perinatal 10, no. 3 (November 17, 2021): 10–11. http://dx.doi.org/10.33421/inmp.2021235.

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Estimado señor editor: Luego de haber leído con interés el artículo “Factores asociados al nivel de conocimiento sobre lactancia materna exclusiva en madres primíparas atendidas por Teleconsulta – Instituto Nacional Materno Perinatal en el año 2020” por Vizquerra-Guevara P, et al. publicado en el Volumen 10 número 1 de la Revista Peruana de Investigación Materno Perinatal, el cual considero un estudio de suma relevancia en el campo de la Obstetricia sobre todo en el campo de la Educación Materna; y teniendo en cuenta que en el año 2019, según ENDES el 65,6% de niñas y niños menores de seis meses tuvieron lactancia materna1; quisiera acotar algunos aspectos que deberían considerarse para posteriores estudios. Según la OMS y la UNICEF los diez pasos hacia una feliz lactancia natural (revisión 2018), se ha de cumplir con el paso 3 de información prenatal- Explicar a las mujeres embarazadas y a sus familias la importancia de la lactancia materna y su práctica2. Actualmente en las sesiones de psicoprofilaxis obstétrica, R.M. N° 361-2011 MINSA en la sesión V brinda actividades educativas de Lactancia Materna, dicha guía es de aplicación en todos los establecimientos del Ministerio de Salud a nivel nacional3. Por otra parte, la RM Nº609-2014/MINSA establece la certificación de establecimientos amigos de la madre, la niña y el niño considerando que uno de los criterios de evaluación para la certificación es el paso 3 con los estándares siguientes: Se dispone de material informativo en lactancia materna en los ambientes de atención prenatal. Historias clínicas se encuentran registros de la consejería en lactancia materna durante la atención prenatal. Gestantes entrevistadas describen los riesgos de dar suplementos alimenticios en los primeros seis meses: describen la importancia del contacto precoz piel a piel y la importancia del inicio de la lactancia dentro de la primera hora de nacido. Gestantes entrevistadas conocen la importancia de la lactancia y refieren que el personal las ayuda a incrementar su propia confianza y seguridad. Personal entrevistado que atiende a las mujeres embarazadas demuestra que toca los temas claves en la consejería verbal durante la Atención prenatal4. Asimismo; la RM Nº 353-2016/MINSA en el paso 3 establece que si el establecimiento de salud tiene al menos un servicio de atención prenatal debe ofrece la consejería de lactancia materna a las gestantes y a su familia acerca de la importancia de la lactancia, de los riesgos de no amamantar, de proporcionar sucedáneos, biberones, chupones, suplementos alimenticios y materiales para la alimentación artificial, la importancia de dar de lactar durante la primera hora de vida de su recién nacido, del contacto piel a piel, el pinzamiento oportuno del cordón umbilical, alojamiento conjunto y la lactancia materna a libre demanda5. Es importante considerar las recomendaciones del MINSA sobre criterios, parámetros, indicadores que nos ayudan a medir el nivel de conocimiento sobre lactancia materna y la apertura de un consultorio de consejería en lactancia materna para las gestantes. La aplicación de toda la información indicada nos servirá como evidencias del trabajo que realiza la institución y el logro alcanzado.
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7

Olsak, Petr. "News in OFS." Zpravodaj Československého sdružení uživatelů TeXu 14, no. 3-4 (2004): 145–56. http://dx.doi.org/10.5300/2004-3-4/145.

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8

Mendes, Marlon Jose Gavlik, Tânia Maria Rechia Schroeder, and Fátima Elisabeth Denari. "Violência contra pessoas com deficiência: um estudo de caso (Violence against people with disabilities: a case report)." Revista Eletrônica de Educação 14 (April 13, 2020): 3308080. http://dx.doi.org/10.14244/198271993308.

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The life of people with disabilities are marked by adverse situations, like architectural barriers, communication barriers and attitudinal barriers, This group also suffers from violent situations in their daily lifes, such as physical and verbal aggression. In the current scientific production, there is few researches that investigates the discourse of the person victim of violence, a fact that, on one hand, may characterize some ignorance of the situations experienced by these people, and, on the other hand, may result in discredit of the discourse of people with disabilities. The objective of this research was to investigate the violence experienced by people with disabilities through a case study of a young person with physical disability. The research was descriptive and had a qualitative nature, using the theoretical framework of the Sociology of disability, Violence and Stigma. Semi-structured interview was conducted, using Comprehensive Sociology as a data analysis tool. The results showed that insults and exclusions are a part of the daily life of the young, actions that can be classified as bullying. The young experience several conflicts in the school environment, having some of these conflicts resolved through the mediation of professionals. Violence against people with disabilities is a dynamic and recurring phenomenon, requiring prevention and intervention programs in the school and other researches on the theme that focuses on the victim point of view.ResumoA vida das pessoas com deficiência é marcada por situações adversas, como barreiras físicas, comunicacionais e atitudinais. Esse grupo também sofre de situações violentas em seu cotidiano, como agressões físicas e verbais. Na produção científica atual se notam poucas pesquisas que investigam o discurso da própria pessoa vítima de violência, fato esse que, de um lado, pode caracterizar desconhecimento das situações vividas por essas pessoas e, por outro, pode resultar em um descrédito em relação ao discurso das pessoas com deficiência. Nesse sentido, o objetivo desta pesquisa foi investigar as violências vividas por pessoas com deficiência por meio de um estudo de caso de um jovem com deficiência física. A pesquisa realizada foi descritiva e de natureza qualitativa, utilizando-se do referencial teórico da Sociologia da Deficiência, da Violência e do Estigma. Foi realizada entrevista a partir de um roteiro semiestruturado de questões, sendo utilizada a Sociologia Compreensiva como ferramenta de análise dos dados. Os resultados mostraram que xingamentos e exclusões fazem parte do cotidiano do jovem com deficiência, ações tais que podem, legalmente, ser tidas como bullying. O jovem vive diversos conflitos no ambiente escolar, tendo alguns desses conflitos resolvidos a partir da mediação de profissionais. A violência contra as pessoas com deficiência é um fenômeno dinâmico e recorrente, são necessários programas de prevenção e de intervenção no ambiente escolar, além de outras pesquisas sobre a temática que focalizem a perspectiva da vítima.Palavras-chave: Violência, Pessoas com deficiência, Estigma, Bullying.Keywords: Violence, Disabled Persons, Stigma, Bullying.ReferencesABRAMOVAY, M. Cotidiano das escolas: entre violências. Brasília, DF: Unesco, Observatório de Violência, Ministério da Educação 2006.AMARAL, L. A. Sobre crocodilos e avestruzes: falando de diferenças físicas, preconceitos e sua superação. In: Diferenças e preconceito na escola: alternativas teóricas e práticas. Volume 5. São Paulo: Summus, 1998. p. 11-30.ARANHA, M. S. F. Paradigmas da relação da sociedade com as pessoas com deficiência. Revista do Ministério Público do Trabalho, v. 11, n. 21, p. 160-173, 2001.BARROS, A. C. M. W.; DESLANDES, S. F.; BASTOS, O. M. A violência familiar e a criança e o adolescente com deficiências. Cadernos de Saúde Pública, v. 32, 2016.BENETTI, D. S. Efeitos de um treino de habilidades para a vida junto a adolescentes com deficiência intelectual e em situação de acolhimento. 2015. Tese (Doutorado em Educação e Ciências Humanas). Programa de Pós-Graduação em Educação Especial. Universidade Federal de São Carlos, 2015.BIANCHETTI, L. Os trabalhos e os dias dos deuses e dos homens: a mitologia como fonte para refletir sobre normalidade e deficiência. Revista Brasileira de Educação Especial, v. 7, n. 1, p. 61-75, 2001.BONI, V.; QUARESMA, S. J. Aprendendo a entrevistar: como fazer entrevistas em Ciências Sociais. Em Tese, v. 2, n. 1, p. 68-80, 2005.BORGES, L.; CAMPOS, J. A. P. P. Fatores determinantes ao ingresso de alunos com deficiência no ensino médio. Psicologia Educacional, São Paulo, n. 44, p. 79-91, jun. 2017.BOTELHO, R. G.; SOUZA, J. M. C. Bullying e educação física na escola: características, casos, conseqüências e estratégias de intervenção. Revista de Educação Física/Journal of Physical Education, v. 76, n. 139, 2007.BRANDÃO, E. C.; MATIAZI, L. D. Bullying: Violência socioeducacional – desafio permanente. Pedagogia em Ação, v. 9, n. 1, p. 17-33, 2017.BRASIL. Estatuto da Pessoa com Deficiência. Lei Brasileira de Inclusão. Lei nº 13.146, de 6 de julho de 2015. Presidência da República, Brasília/DF; 2015.CHARLOT, B. A violência na escola: como os sociólogos franceses abordam essa questão. Sociologias, Porto Alegre, n. 8, p. 432-443, 2002.CUNHA, M, J.; PINTO, P. C. Representaciones mediáticas de la deficiencia: un estudio longitudinal en la prensa. Sociologia, Problemas e Práticas, Lisboa, n. 85, p. 131-147, set. 2017.EMERICH, D. R.; ALCKMIN-CARVALHO, F.; SILVA, M. H. M. Rejeição e vitimização por pares em crianças com deficiência intelectual e transtorno do espectro autista. Revista Educação Especial, v. 30, n. 58, 2017.FERNANDES, A. P. C. S.; DENARI, F. E. Pessoa com deficiência: estigma e identidade. Revista da FAEEBA Educação e Contemporaneidade, v. 26, n. 50, p. 77-89, 2017.FOUCAULT, M. Vigiar e punir: o nascimento da prisão. Tradução R. Ramalhete. 21. ed. Petrópolis, RJ: Vozes; 1999.FRASER, M. T. D.; GONDIM, S. M. G. Da fala do outro ao texto negociado: discussões sobre a entrevista na pesquisa qualitativa. Paidéia, v. 14, n. 28, p. 139-152, 2004.GOFFMAN, E. Estigma: notas sobre a manipulação da identidade deteriorada. Rio de Janeiro: Coletivo Sabotagem, 1988.GOMES, A. E. G.; REZENDE, L. K. Reflexões sobre bullying na realidade brasileira utilizando a técnica de análise de conteúdo: revisão bibliográfica. Cadernos de Pós-Graduação em Distúrbios do Desenvolvimento, v. 11, n. 1, 2018.GUIMARÃES, A. M. A dinâmica da violência escolar: conflito e ambiguidade. Campinas, SP: Editora Autores Associados, 1996.HARLOS, F. E. Sociologia da deficiência: vozes por significados e práticas (mais) inclusivas. 2012. 201 f. Dissertação (Mestrado em Educação Especial ? Educação do Indivíduo Especial) ? Universidade Federal de São Carlos, São Carlos, 2012.MAFFESOLI, M. Dinâmica da violência. São Paulo: Editora Revista dos Tribunais, 1987.MAFFESOLI, M. Elogio da razão sensível. Petrópolis, RJ: Vozes, 1998.MAFFESOLI, M. Entre o bem e o mal. Compêndio de subversão pós-moderna. Lisboa: Instituto Piaget, 2002.MAFFESOLI, M. O conhecimento comum: introdução à sociologia compreensiva. Porto Alegre: Sulina, 2007.MAGNABOSCO, M. B.; SOUZA, L. L. Educação inclusiva e as representações dos estudantes sobre seus pares com deficiência. Psicologia Escolar e Educacional, v. 22, n. 1, p. 115-122, 2018.MAZZOTTA, M. J. S.; D'ANTINO, M. E. F. Inclusão social de pessoas com deficiências e necessidades especiais: cultura, educação e lazer. Saúde e Sociedade, v. 20, p. 377-389, 2011.MENDES, C. S. Prevenção da violência escolar: avaliação de um programa de intervenção. Revista da Escola de Enfermagem da USP, v. 45, n. 3, p. 581-588, 2011.MENDES, E. G. Breve histórico da educação especial no Brasil. Revista Educación y Pedagogía, v. 22, n. 57, maio/ago. 2010.MOREIRA, M. C. N.; BASTOS, O. M.; BASTOS, L. C.; SOARES, A. H. R.; SOUZA, W. D. S.; SANCHEZ, R. N. Violência contra crianças e adolescentes com deficiência: narrativas com conselheiros tutelares. Ciência e Saúde Coletiva, v. 19, p. 3869-3878, 2014.ORGANIZAÇÃO MUNDIAL DA SAÚDE (OMS). CIF: Classificação Internacional de Funcionalidade, Incapacidade e Saúde. Organização Mundial da Saúde. Lisboa; 2004.ORGANIZAÇÃO MUNDIAL DA SAÚDE (OMS). World report on violence and health. World Health Organization. Geneva; 2002.PAULINO, V. C.; CAIADO, K. R. M. A construção do conceito de deficiência por estudantes sem deficiência, a partir de suas histórias de vida. Educação em Foco, v. 20, n. 32, p. 35-59, 2017.SÃO PAULO. Serviço de Acolhimento Institucional para Crianças e Adolescentes. Prefeitura Municipal de São Paulo. 2017. Disponível em: <https://www.prefeitura.sp.gov.br/cidade/secretarias/assistencia_social/protecao_social_especial/index.php?p=28980>. Acesso em: 6 set. 2019.SILVA, F. R.; ASSIS, S. G. Prevenção da violência escolar: uma revisão da literatura. Educação e Pesquisa, São Paulo, v. 44. 2018.SILVA, J. L. D.; OLIVEIRA, W. A. D.; SILVA, M. A. I. D.; PEREIRA, B. O.; CECILIO, S. Estudo exploratório sobre as concepções e estratégias de intervenção de professores em face do bullying escolar. Psicologia, Sa?o Paulo, Brasil, v. 17, n. 3, p. 189-199, 2015.SIMMEL, G. A natureza sociológica do conflito. In: MORAES FILHO, E. (Org.). Simmel. São Paulo: Ática, 1983. p. 122-134.STELKO-PEREIRA, A. C.; WILLIAMS, L. C. A. Reflexões sobre o conceito de violência escolar e a busca por uma definição abrangente. Temas Psicológicos, Ribeirão Preto/SP, v. 18, n. 1, p. 45-55, 2010.STELKO-PEREIRA, A. C. Avaliação de um programa preventivo de violência escolar: planejamento, implantação e eficácia. 2012. 193 f. Tese (Doutorado em Psicologia), Universidade Federal de São Carlos, São Carlos. 2012.VIEIRA, C. M.; DENARI, F. E. Programa informativo sobre deficiência mental e inclusão: mudanças nas atitudes sociais de crianças sem deficiência. Revista Brasileira de Educação Especial, Marília/SP, v. 18, n. 2, p. 265-282, 2012.WILLIAMS, L. C. A. Sobre deficiência e violência: reflexões para uma análise de revisão de área. Revista Brasileira de Educação Especial, v. 9, n. 2, p. 141-154, 2003.YIN, R. K. Estudo de caso: planejamento e método. Porto Alegre, RS: Bookman, 2001.e3308080
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Cao, Taotao, Hu Liu, Anyang Pan, Mo Deng, Qinggu Cao, Ye Yu, Yanran Huang, and Zhenghui Xiao. "Marine Shale Gas Occurrence and Its Influencing Factors: A Case Study from the Wufeng-Longmaxi Formation, Northwestern Guizhou, China." Geofluids 2022 (March 23, 2022): 1–27. http://dx.doi.org/10.1155/2022/2036451.

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Organic-rich shales were found in the Ordovician to Silurian Wufeng-Longmaxi Formation in northwestern Guizhou province, China, which has high shale gas content revealed by field measurement. Shale gas occurrence, free gas/sorbed gas ratio, and their influencing factors are crucial for shale gas exploitation strategy. Results indicated that the Wufeng-Longmaxi shales are dominated by type I kerogen, with total organic carbon (TOC) and equivalent vitrinite reflectance (eqvRo) of 0.77%–6.98% and 2.37%–2.53%, respectively. The total porosity and permeability are in the range of 1.23%–8.43% and 3 × 10 − 4 – 2.23 × 10 − 1 mD, respectively. FE-SEM observation and correlation analysis show shale porosity is dominated by organic matter (OM) pores, followed by interparticle (interP) pores related to brittle minerals. CH4, derived from oil cracking, is the main component of shale gas, but its proportion is lower than that in Fuling and Weiyuan areas, probably due to the weak preservation condition. Desorption gas and lost gas determined by in situ desorption test are 0.42–1.54 cm3/g and 1.9–7.14 cm3/g, respectively, and Langmuir volume ( V L ) from isothermal adsorption experiment is 1.63–4.78 cm3/g. Shale gas content is positively correlated with micropore volume, mesopore volume and TOC content but negatively correlated with macropore volume and clay mineral content, indicating that methane is preferentially stored in micropores (<2 nm) and mesopores (2–50 nm) related to OMs. By comparing actual total gas content with theoretical gas content, shale gas is considered to exist primarily in sorbed state, and the free gas proportion can increase with increased TOC content, due to that OM pores with larger sizes are also main space for free gas. Combined with the two methods, it can result in accurate calculations of shale gas reserves and free/sorbed gas ratio. Based on this understanding, a model of shale gas occurrence was proposed, which can provide a reference for shale gas exploitation in normal pressure areas.
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Gritsch, Stephan. "Compact Stage V Power." Industrial Vehicle Technology International 26, no. 4 (November 2018): 85. http://dx.doi.org/10.12968/s1471-115x(23)70605-3.

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Mera Navarrete, María José, Isabel Cristina Mesa Cano, Pedro Carlos Martínez Suárez, and Andrés Alexis Ramírez Coronel. "Impacto psicológico frente al COVID-19 en los internos de enfermería de prácticas pre-profesionales." Universidad Ciencia y Tecnología 25, no. 109 (June 2, 2021): 53–59. http://dx.doi.org/10.47460/uct.v25i109.448.

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Se estudió el impacto psicológico frene al COVID – 19 en los internos de enfermería de prácticas pre – profesionales en relación a las variables sociodemográficas y los niveles de ansiedad, depresión y miedo. Para el análisis se consideró a 150 internos prácticos de la carrera de enfermería, para la evaluación de este estudio se utilizaron las escalas de STAI, IDER, FCV19S y K10. Los resultados exponen que existe mayor nivel de ansiedad en los internos que declararon no tener equipos de bioseguridad necesarios. Los internos que rotan en el área hospitalaria presentan mayores niveles de ansiedad, miedo y malestar psicológico compara con los internos del área comunitaria. Sin embargo, los niveles de depresión fueron ligeramente mayores en los internos de área comunitaria. No hubo diferencia significativa de los estados emocionales entre mujeres y varones. Palabras Clave: Ansiedad, depresión, miedo al COVID-19, impacto psicológico. Referencias [1]M. Del Campo, «Covid-19 y su impacto en la salud y el trabajo,» Revista de la Asociación Española de Especialistas en Medicina del Trabajo, vol. 29, nº 3, p. 183, 2020. [2]H. Scholten, VE. Quezada-Scholz, G.Salas, NA. Barria Aseenio, R. Molina, JE. García, M. Juliá, A. Marinero, A. Zambrano, E. Gómez, A. Cheroni, T. Caycho-Rodriguez, T. Reyes, N. Pinochet, P. Binde, J. Uribe, C. Rojas, J. Bernal, F. Somarriva, “Abordaje psicológico del COVID-19: Una revisión narrativa de la experiencia latinoamericana,” Rev Interam Psicol J Psychol, vol. 54, pp.287, May. 2020. [3]A. Tusev, L. Tonon, y M. Capella, “Efectos Iniciales en la Salud Mental por la Pandemia de Covid-19 en algunas Provincias de Ecuador”, IRR, vol. 15, pp. 11-24, oct. 2020. [4]Ministerio de Salud Pública (2020, marzo 13) Informe de situación N° 001.[En línea]. Disponible en: https://www.gestionderiesgos.gob.ec/wp-content/uploads/2020/03/Informe-de-Situaci%C3%B3n-No001-Casos-Coronavirus-Ecuador-12032020.pdf [5]F. De Caneva, M. García-Gómez, E Baur, “Salud emocional del personal sanitario del Área de Urgencias durante la pandemia COVID-19”, Rev. Med Clin. Vol. 155, no. 8, pp. 365, junio 2020. [6]S Dubey, P. Biswas, R. Ghosh, S. Chatterjee, MJ. Dubey, S. Chatterjee, D. Lahiri, CJ. Lavie, “Psychosocial impact of COVID-19”, Rev Diabetes Metab Syndr. Vol.14, no. 5, pp. 779-788, septiembre-octubre. 2020. [7]G. Arias, F. Navarrete, M. Flor, “Factores asociados al bienestar psicológico de los estudiantes de la escuela académico-profesional de odontología de la Universidad nacional Jorge Basadre Grohmann”, Revista médica Basadrina. Vol. 7, no. 2, pp. 28-30, septiembre. 2013. [8]S. Sandoval, A. Dorner, A. Véliz, “Bienestar psicológico en estudiantes de carreras de la salud,” Rev Investigación en Educación Médica, Vol. 6, no. 24, pp.260-266, diciembre 2017. [9]C. Mitchell, OPS/OMS | La OMS (2020, octubre 23) caracteriza a COVID-19 como una pandemia. Pan American Health Organization / World Health Organization [En línea] Disponible en: https://www.paho.org/hq/index.php?option=-com_content&view=article&id=15756:who-characterizes-covid-19-as-a-pandemic&Itemid=1926&lang=es [10]MC. Johnson, L. Saletti-Cuesta, N. Tumas, “Emociones, preocupaciones y reflexiones frente a la pandemia del COVID-19 en Argentina,” Rev Ciênc Saúde Coletiva, vol 25(suppl 1), pp. 2447-56, junio. 2020. [11]L. Hernani, A. Aquino, E. Araujo, “Relación entre el bienestar auto percibido, autoestima, inteligencia emocional, personalidad y razonamiento, abstracto en un grupo de estudiantes universitarios,” Revista peruana de Psicología y trabajo social, vol. 2, no. 1, pp. 49-62, mayo. 2013. [12]N. Ozamiz-Etxebarria, M. Dosil-Santamaria, M. Picaza-Gorrochategui, N. Idoiaga-Mondragon, “Niveles de estrés, ansiedad y depresión en la primera fase del brote del COVID-19 en una muestra recogida en el norte de España,” Cad Saúde Pública, vol. 36, no. 4, abril. 2020. [13]H. Blake, F. Bermingham, G. Johnson, and A. Tabner, “Mitigating the Psychological Impact of COVID-19 on Healthcare Workers: A Digital Learning Package,” International Journal of Environmental Research and Public Health, vol. 17, no. 9, pp. 2997, abril 2020. [14]M. Walton, E. Murray, MD. Christian, “Mental health care for medical staff and affiliated healthcare workers during the COVID-19 pandemic,” Rev. Eur Heart J Acute Cardiovasc Care, vol. 9, no. 3, pp. 241-247, Abril. 2020. [15]J. Shijo, P. Gunaseelan, S. Bhandari, S. Dutta, “How the novel coronavirus (COVID-19) could have a quivering impact on mental health?,” Rev. Open J Psychiatry Allied Sci, vol.11, no. 2, pp.135-136, julio-diciembre. 2020. [16]W. El-Hage, C. Hingray, C. Lemogne, A. Yrondi, P. Brunault, T. Bienvenu, B. Etain, C. Paquet, B. Gohier, D Bennabi, P. Birmes, A. Sauvaget, E. Fakra, N. Prieto, S. Bulteau, P. Vidailhet, V. Camus, M. Levoyer, M. Krebs, B. Aouizerate, “Les professionnels de santé face à la pandémie de la maladie à coronavirus (COVID-19): quels risques pour leur santé mentale ?,” Rev. L’Encephale, vol. 46, no. 3, pp.73-80, octubre, 2020. [17]Sociedad Española de psiquiatría. “Cuidado de la salud mental del personal sanitario”. 2020 [En línea] Disponible en: http://www.sepsiq.org/file/InformacionSM/SEP%20COVID19-Salud%20Mental%20personal%20sanitario.pdf [18]A. Lozano-Vargas, “Impacto de la epidemia del Coronavirus (COVID-19) en la salud mental del personal de salud y en la población general de China,” Rev Neuropsiquiatr, vol. 83, pp. 51-6, enero, 2020. [19]D. Talevi, V. Socci, M. Carai, G. Carnaghi, S. Faleri, E.Trebbi, A. Di Bernardo, F. Capelli, F. Pacitti, “Mental health outcomes of the CoViD-19 pandemic,” Riv Psichiatr, vol. 55, no. 3, pp. 137-144, mayo-junio, 2020. [20]A. Urzúa, P. Vera-Villarroel, A. Caqueo-Urízar, R. Polanco-Carrasco, “La Psicología en la prevención y manejo del COVID-19. Aportes desde la evidencia inicial,” Rev. Ter Psicológica, vol. 38, pp. 103-18, abril, 2020. [21]R. Sierra. Técnicas de investigación social. 9na Edición. Madrid. Ed.Paraninfo S.A. 1988. [22]C. Spielberger, R. Gorsuch, R. Lushene. “Cuestionario de Ansiedad Estado-Rasgo”. TEA: Ediciones, 2015. [En línea] Disponible en: http://www.web.teaediciones.com/Ejemplos/STAI-Manual-Extracto.pdf [23]D. Gudelo, Y. Gómez, P. López, “Propiedades Psicométricas del Inventario de Depresión Estado Rasgo (IDER) con una muestra de población general colombiana,” Rev. Av En Psicol Latinoam, vol. 32, no 1, pp. 71-84, 2014. [24]D. Tzur, A. Grossman-Giron, Y. Bloch, Y. Mayer, N. Shiffman, S. Mendlovic, “Fear of COVID-19 scale: Psychometric characteristics, reliability and validity in the Israeli population,”Rev.Psychiatry, vol. 289, pp. 113100, julio, 2020. [25]B. Vargas, V. Villamil, C. Rodríguez, J. Pérez, S. Cortés, “Validación de la escala Kessler 10 (K-10) en la detección de depresión y ansiedad en el primer nivel de atención. Propiedades psicométricas,” Rev. Salud Ment, vol. 34, pp. 323-331, julio-agosto 2011.
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Vargas Aguilar, Germania Marivel, María Elena Olaya Pincay, Delia Suarez Vera, and Victoria Stepenka Álvarez. "INCIDENCIA DE LA VALORACIÓN DE ENFERMERÍA EN EL AUTOCUIDADO DEL ADULTO MAYOR." Universidad Ciencia y Tecnología 24, no. 105 (October 11, 2020): 35–42. http://dx.doi.org/10.47460/uct.v24i105.379.

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La intervención del personal de enfermería en el autocuidado del adulto mayor es indispensable para asegurar un tratamiento adecuado de la salud. En este trabajo se analizaron 50 historias clínicas para reconocer la participación de la valoración de enfermería en la salud de los adultos mayores. Los resultados revelaron que es necesaria una mayor promoción de salud, para que el paciente comprenda la importancia, y adquiera una mejor disposición hacia el autocuidado. Con respecto al aspecto nutricional, fue posible observar que el riesgo de nivel de glicemia inestable se ubica en el 82%, por lo que es necesario a su vez, hacerle saber la importancia de la nutrición adecuada. Por otro lado, en el área de la actividad física se evidenció el deterioro de ambulación, en un 90%, mientras que el riesgo de caída estuvo en un 80%. Estos resultados apuntan a la necesidad de reforzar la atención en el adulto mayor, enfocándose principalmente en las actividades formativas para su cuidado. Palabras Clave: adulto mayor, cuidados en la salud, gestión de enfermería. Referencias [1]G. Vargas, M. Lozano y Q. Rina, «Aproximación Teórica del Autocuidado del adulto mayor y los paradigmas de enfermería,» Universidad Ciencia y Tecnología, vol. 1, nº número especial, 2020. [2]Organización Panamericana de Salud , La Agenda de Salud de las Américas 2008-2017, Bogotá: OPS Colombia, 2012. [3]Organización Mundial de la Salud, 10 datos del envejecimiento y la salud, Washington, D. C: Editado por OMS: http://www.who.int/features/factfiles/ageing/es/, 2018. [4]A. Maita, Riesgos de accidentes en el adulto mayor que realiza actividades de rutina, usuarios de los servicios del Centro de Salud Conde de la Vega Baja, Lima 2014, Lima, Perú: Universidad Nacional Mayor de San Marcos. Facultad de Medicina. EAP de Enfermería, 2017. [5]P. Potter, A. Perry, P. Stockert y H. Amy, Fundamentos de Enfermería, Barcelona: Elsevier, 2015. [6]R. Salcedo, B. González, A. Mendoza, V. Nava, D. Cortés y M. Eugenio, «Autocuidado para el control de la hipertensión arterial en adultos mayores ambulatorios: una aproximación a la taxonomía NANDA-NOC-NIC,» Enfermería Universitaria, vol. 9, nº 3, p. 15, 2015. [7]Organización Panamericana de la Salud , Enseñanza de la enfermeria en salud del adulto mayor, Washington: OPS, 2012. [8]M. Abreu, G. Badin, E. Franzen, E. Da Rocha, M. Rubin, E. Rejane, M. Machado y M. Moraes, «Diagnósticos de enfermería e intervenciones prevalentes en el cuidado al anciano hospitalizado,» Revista Latinoamericana de Enfermería, vol. 16, nº 4, p. 10, 2016. [9]C. González y C. Chávez, Conocimiento del cuidador sobre factores de riesgo que predisponen los accidentes domiciliarios en el adulto mayor del Centro de Salud #7 Mapasingue. 2012, Guayaquil, Ecuador: Universidad de Guayaquil, Facultad de Ciencias Médicas, Carrera de Enfermería, 2018. [10]J. Silva, S. Ramón, S. Vergaray, V. Palacios y R. Partezani, «Percepción del paciente hospitalizado respecto a la atención de enfermería en un hospital público,» Elsevier, vol. 12, nº 2, pp. 80-87, 2015. [11]L. Ponti, R. Castillo , R. Vignatti, M. Monaco y J. Nuñez, Conocimientos y dificultades del proceso de atención de enfermería en la práctica, Túlcán, Ecuador:http://www.ems.sld.cu/index.php/ems/article/view/1006/577, 2017. [12]E. De Reales, El Proceso de Atención de Enfermería., Bogotá: Facultad de enfermería. Universidad Nacional de Bogotá, 2016. [13]G. Soliz, Salud integral y derechos del adulto mayor, Cuenca- Ecuador: Universidad de Cuenca https://dspace.ucuenca.edu.ec/bitstream/123456789/23361/1/15.pdf, 2015. [14]Organización Mundial de la Salud, Adultos mayores, Washington, D. C: Editado por OMS: http://www.who.int/mediacentre/factsheets/fs381/es/, 2015. [15]P. R. Gallegos, Aprendiendo el Desarrollo Endógeno Sostenible Construyendo la Diversidad Bio-cultural., Bolivia: Plural editores. Cuarta edición., 2015. [16]A. Ocampo, Manual de Atención de Enfermería a pacientes con edad adulta., México: Editorial Panamericana. Primera Edición, 2015. [17]OREM, Modelos y teorías, Barcelona: Cientificas y Técnicas S.A, 1999. [18]M. y. W. M. Burke, Enfermería gerontológica. Cuidados integrales del adulto mayor., Washington.: Editorial Harcourt Brace. Cuarta edición, 2015. [19]F. Guillén, Manual de Geriatría, Barcelona: Edita Masson. Tercera Edición., 2018. [20]NANDA INTERNACIONAL, DIAGNOSTICOS DE ENFERMERIA, 2018. [21]F. Lolas, La Familia y el Anciano.., La Habana – Cuba: Editorial Científico-Técnica. Cuarta edición. , 2012. [22]M. Ortega y D. Suarez, «Diagnósticos de enfermería mas relevantes en el autocuidado del adulto mayor,» Guayaquil, 2020. [23]L. Buitrago, L. Cordon y R. Cortés, «Niveles de ansiedad y estrés en adultos mayores en la condición de abandono Familiar,» Revista científica y profesional de la Asociación Latinoamericana para la Formación y la Enseñanza de la Psicología . Volumen 6. Número 17. 2018., pp. pp. 70-82, 2016. [24]Y. Naranjo y J. Concepción, «Importancia del autocuidado en el adulto mayor con diabetes,» Revista Finlay, pp. pp. 215 - 222, 2016.
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Kashem, Md Tashfiq Bin, Sadid Muneer, Lhacene Adnane, Faruk Dirisaglik, Ali Gokirmak, and Helena Silva. "(Digital Presentation) Calculation of the Energy Band Diagram and Estimation of Electronic Transport Parameters of Metastable Amorphous Ge2Sb2Te5." ECS Meeting Abstracts MA2022-01, no. 18 (July 7, 2022): 1043. http://dx.doi.org/10.1149/ma2022-01181043mtgabs.

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Phase change memory (PCM) is a high speed, high density non-volatile resistive memory technology that utilizes different phases (crystalline and amorphous) of phase change materials such as Ge2Sb2Te5 (GST) to store information [1]. Here, the material undergoes two types of reversible switching phenomena: (i) Ovonic Threshold Switching (OTS), which causes the amorphous phase of the material to switch from a highly resistive state to conductive state with application of high electric fields, resulting in current flow and (ii) Ovonic Memory Switching (OMS), which is due to the change of the phase of the material between amorphous and crystalline phases induced by heating [2]. Even though PCM entered high volume manufacturing, the electronic properties of the phase change materials are still not well understood [3,4]. In this work, we construct the energy band diagram of amorphous GST as a function of temperature using a temperature dependent model of effective activation energy of conduction in metastable amorphous GST [5], which we obtained from high-speed experiments on GST line-cells [6]. Assuming the bandgap energy to linearly decrease with temperature [7,8] and p-type conduction (based on positive Seebeck coefficients measured in a wide temperature range [9]) , we determine a temperature dependent Fermi energy level from 0K to melting temperature, Tmelt ~ 858 K. Liquid GST is expected to become metallic (bandgap collapsing to 0) at ~ 894K, based on the experimental results. We also estimate the carrier concentration at Tmelt utilizing the latent heat of fusion (126 kJ/kg) [10] to be pmelt = 1.47 x 1022 cm-3. Using the melt resistivity measured on GST thin film, we calculate the carrier mobility at melting point as µmelt ~0.187 cm2/V-s, close to the previously reported value of 0.15 cm2/V-s based on crystalline state mobility and a density of states calculation [2]. Assuming a weak temperature dependence of the mobility [5], we obtain the carrier concentration of ~3.37× 1017 cm-3 at room temperature which lies within the ~1017-1018 cm-3 range estimated in a former study [3]. Finally, we calculate conduction activation energy of as-deposited amorphous GST from temperature dependent Seebeck coefficient measured simultaneously with the resistance [9]. The activation energy varies as a parabolic function of temperature where it starts from 0 eV at 0 K, reaches a peak of ~0.257 eV near glass transition temperature (~400 K) with the room temperature value of ~0.24 eV and becomes 0 eV again at ~810 K. We also utilize the Seebeck coefficient measurements along with the band edges and Fermi energy level information from the energy band diagram to calculate the ratio of minority carrier concentration to the total carrier concentration as a function of temperature; this is useful to predict the temperature beyond which bipolar conduction becomes significant. Acknowledgment: Analysis is performed with the support of US National Science Foundation (NSF) award ECCS 1711626. The experimental data used for this analysis were collected with the support of US NSF DMR-1710468 on devices fabricated with the support of US Department of Energy Office of Basic Energy Sciences. References: [1] S. W. Fong et al., IEEE Trans. Electron Devices, vol. 64, no. 11, pp. 4374–4385, 2017. [2] A. Pirovano et al., IEEE Trans. Electron Devices, vol. 51, no. 3, pp. 452–459, 2004. [3] T. Kato et al., Japanese J. Appl. Physics, vol. 44, no. 10, pp. 7340–7344, 2005. [4] M. Schumacher et al., Sci. Rep., vol. 6, no. June, pp. 1–11, 2016. [5] S. Muneer et al., AIP Adv., vol. 8, no. 6, p. 65314, Jun. 2018. [6] F. Dirisaglik et al., Nanoscale, vol. 7, no. 40, pp. 16625–16630, 2015. [7] E. M. Vinod et al., J. Non. Cryst. Solids, vol. 356, no. 41–42, pp. 2172–2174, 2010. [8] Y. Kim et al., Appl. Phys. Lett., vol. 90, no. 17, pp. 1–4, 2007. [9] L. Adnane et al., J. Appl. Phys., vol. 122, no. 12, 2017. [10] Z. Fan et al., Japanese J. Appl. Physics, vol. 42, no. 2 B, pp. 800–803, 2003.
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Gerber Hornink, Gabriel, Vera Maria Treis Trindade, Eduardo Galembeck, and Bayardo Baptista Torres. "Editorial 2016 - V. 14 - N. 3." Revista de Ensino de Bioquímica 14, no. 3 (December 15, 2016): 5. http://dx.doi.org/10.16923/reb.v14i3.740.

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O ano de 2016 foi importante para o processo de internacionalização da Revista de Ensino de Bioquímica. No primeiro semestre, tivemos um artigo com autores da Argentina e neste número temos a publicação de artigos em português e inglês, sendo um trabalho com equipe da Austrália e outro do Egito. Durante o mês de dezembro trabalhamos em diversas melhorias técnicas da revista, atualizando o sistema Open Journal System (OJS) da versão 2.4.5 para 2.4.8-1, o que possibilitou melhorias na segurança do sistema, implementação do sistema LOCKSS, o que garantirá maior permanência na internet dos arquivos da revista.Além disso, a nova versão do OJS possibilita melhor integração com o sistema da Crossref, o que possibilitará a implantação do sistema iThenticate, o qual possibilita o serviço de verificação de plágio. Com o sistema iThenticate, a REB amplia suas ações no caminho de dar maior seriedade e confiança nas pesquisas publicadas na revista, contribuindo com a comunidade científica, de modo geral, no combate ao plágio acadêmico.Durante este semestre, parte da equipe da revista trabalhou em uma proposta integrada para a 43a reunião anual da SBBq, visando ampliar as ações envolvendo o ensino de Bioquímica e Biologia Molecular. Para 2017 planejamos conferência e simpósio na área de Educação, dois minicursos, além do estande da revista que, além de divulgar os trabalhos da revista, também será espaço para mostra de materiais e práticas educacionais que foram avaliadas na primeira edição do Prêmio Nacional de Ensino de Bioquímica e Biologia Molecular Bayardo Baptista Torres.Destacamos que as melhorias nos serviços da revista, assim como a primeira edição do Prêmio Nacional de Ensino de Bioquímica e Biologia Molecular Bayardo Baptista Torres foram possíveis a partir dos recursos advindos da Sociedade Brasileira de Bioquímica e Biologia Molecular, a qual também é responsável pela publicação da revista.O terceiro número de 2016 tem artigos nas seções Pesquisa em Ensino, Inovações Educacionais e REB na Escola.A seção “Pesquisa em ensino” se inicia com um artigo que busca realizar uma revisão sistemática dos trabalhos publicados entre 2014 e 2015, focando na identificação das estratégias didáticas utilizadas para o ensino de Bioquímica.Publicaram-se dois artigos n seção “Inovações Educacionais”, ambos internacionais, o primeiro abordado uma metodologia de ensino (Unidade Metabólica Baseada em Casos – CBMU) utilizada em um curso de medicina no Egito.O segundo artigo desta seção abordou uma aula prática sobre a purificação de proteínas por meio de cromatografia de afinidade com íon metal imobilizado, assim como sua aplicação com estudantes de graduação em Ciências Biomédicas, disciplina de Bioquímica, em uma universidade da Austrália.A seção “REB na Escola” teve dois artigos nacionais, sendo que o primeiro deles trabalhou oficinas de biotecnologia com estudantes do ensino médio, trabalhando as temáticas de antioxidantes e seu efeito no rejuvenescimento.O último artigo da revista apresentou um jogo com conteúdos de Genética como proposta alternativa para o ensino de replicação de DNA no ensino médio.Destacamos que o enfoque da REB extrapola os artigos de pesquisas acadêmicas sobre ensino de Bioquímica, Biologia Molecular e áreas correlatas, perpassando por boas práticas no ensino superior e básico, além da divulgação científica, sempre buscando propiciar aos leitores materiais que possibilitem a melhoria e a potencialização dos processos de ensino-aprendizagem. AtenciosamenteGabriel G. HorninkUnifal-MGVera Maria T. TrindadeUFRGSEduardo GalembeckUnicampBayardo B. TorresUSP
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Tumber, A., S. Papaioannou, J. Breckon, MC Meikle, JJ Reynolds, and PA Hill. "The effects of serine proteinase inhibitors on bone resorption in vitro." Journal of Endocrinology 178, no. 3 (September 1, 2003): 437–47. http://dx.doi.org/10.1677/joe.0.1780437.

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The aims of this study were to identify the role and sites of action of serine proteinases (SPs) in bone resorption, a process which involves a cascade of events, the central step of which is the removal of bone matrix by osteoclasts (OCs). This resorbing activity, however, is also determined by recruitment of new OCs to future resorption sites and removal of the osteoid layer by osteoblasts (OBs), which enables OCs to gain access to the underlying mineralized bone. The resorption systems we have studied consisted of (i) neonatal calvarial explants, (ii) isolated OCs cultured on ivory slices, (iii) mouse OBs cultured on either radiolabelled type I collagen films or bone-like matrix, (iv) bone marrow cultures to assess OC formation and (v) 17-day-old fetal mouse metatarsal bone rudiments to assess OC migration and fusion. Two separate SP inhibitors, aprotinin and alpha(2)-antiplasmin dose-dependently inhibited (45)Ca release from neonatal calvarial explants: aprotinin (10(-6) M) was the most effective SP inhibitor, producing a maximum inhibitory effect of 55.9%.Neither of the SP inhibitors influenced either OC formation or OC resorptive activity. In contrast, each SP inhibitor dose-dependently inhibited OB-mediated degradation of both type I collagen fibrils and non-mineralized bone matrix. In 17-day-old metatarsal explants aprotinin produced a 55% reduction in the migration of OCs from the periosteum to the mineralized matrix after 3 days in culture but after 6 days in culture aprotinin was without effect on OC migration. Primary mouse osteoblasts expressed mRNA for urokinase type plasminogen activator (uPA), tIssue type plasminogen activator (tPA), the type I receptor for uPA, plasminogen activator inhibitor types I and II and the broad spectrum serine proteinase inhibitor, protease nexin I. In situ hybridization demonstrated expression of tPA and uPA in osteoclasts disaggregated from 6-day-old mouse long bones. We propose that the regulation of these various enzyme systems within bone tIssue determines the sites where bone resorption will be initiated.
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Tevaarwerk, Amye J., Molin Wang, Fengmin Zhao, John H. Fetting, David Cella, Lynne I. Wagner, Silvana Martino, et al. "Phase III Comparison of Tamoxifen Versus Tamoxifen Plus Ovarian Function Suppression in Premenopausal Women With Node-Negative, Hormone Receptor–Positive Breast Cancer (E-3193, INT-0142): A Trial of the Eastern Cooperative Oncology Group." Journal of Clinical Oncology 32, no. 35 (December 10, 2014): 3948–58. http://dx.doi.org/10.1200/jco.2014.55.6993.

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Purpose The effects of ovarian function suppression (OFS) on survival and patient-reported outcomes were evaluated in a phase III trial in which premenopausal women were randomly assigned to tamoxifen with or without OFS. Patients and Methods Premenopausal women with axillary node-negative, hormone receptor–positive breast cancer tumors measuring ≤ 3 cm were randomly assigned to tamoxifen alone versus tamoxifen plus OFS; adjuvant chemotherapy was not permitted. Primary end points were disease-free survival (DFS) and overall survival (OS). Secondary end points included toxicity and patient-reported outcomes. Patient-reported outcome data included health-related quality of life, menopausal symptoms, and sexual function. These were evaluated at baseline, 6 months, 12 months, and then annually for up to 5 years after registration. Results In all, 345 premenopausal women were enrolled: 171 on tamoxifen alone and 174 on tamoxifen plus OFS. With a median follow-up of 9.9 years, there was no significant difference between arms for DFS (5-year rate: 87.9% v 89.7%; log-rank P = .62) or OS (5-year rate: 95.2% v 97.6%; log-rank P = .67). Grade 3 or higher toxicity was more common in the tamoxifen plus OFS arm (22.4% v 12.3%; P = .004). Patients treated with tamoxifen plus OFS had more menopausal symptoms, lower sexual activity, and inferior health-related quality of life at 3-year follow-up (P < .01 for all). Differences diminished with further follow-up. Conclusion When added to tamoxifen, OFS results in more menopausal symptoms and sexual dysfunction, which contributes to inferior self-reported health-related quality of life. Because of early closure, this study is underpowered for drawing conclusions about the impact on survival when adding OFS to tamoxifen.
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Žižlavský, Michal, and Otto Eibl. "Srovnání osobností politických značek ČSSD, ODS a lídrů těchto stran." Sociální studia / Social Studies 8, no. 3 (July 16, 2011): 65–95. http://dx.doi.org/10.5817/soc2011-3-65.

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Branding se stal jedním z nejpopulárnějších nástrojů, který je využíván v politickém marketingu. Mimo jeho praktické využití poskytuje branding analytický rámec, kterým je možné nahlížet na politické strany a na to, jak jsou vnímány voliči. Tento text zkoumá (za využití pro české prostředí modifikované škály Jennifer Aaker), jakým způsobem jsou vnímány osobnosti stran ČSSD a ODS. Výsledky jsou pak srovnány s tím, jak jsou vnímány osobnosti lídrů těchto stran.
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18

Urban, Jiří, Emil Svátek, Miroslav Ryska, Jan Metyš, Stanislav Wildt, and Miroslav Protiva. "4-Aryl-3-(dimethylaminomethyl)thiacyclohexan-4-ols including the thia analogue of tramadol; Synthesis and analgetic activity." Collection of Czechoslovak Chemical Communications 52, no. 5 (1987): 1340–51. http://dx.doi.org/10.1135/cccc19871340.

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Mannich reaction of thiacyclohexan-4-one with dimethylamine and paraformaldehyde afforded 3-(dimethylaminomethyl)thiacyclohexan-4-one (XIV) which was subjected to reactions with a series of arylmagnesium bromides. The products were mixtures of trans- and cis-amino alcohols III-XII from which the predominating trans-components were mostly obtained by crystallization of hydrochlorides or chromatography of bases. The tramadol (I) analogue, i.e. the 3-methoxy compound V, was prepared in the form of both racemates and their relative configuration was confirmed by the IR spectra. Compound V was demethylated to the 3-hydroxyphenyl analogue XIII, transformed to the bis-onium salt XVI, partially N-demethylated to the N-monodemethyl analogue XVII, and oxidized to the sulfoxide XX and to the sulfone N-oxide XXI. Some of the amino alcohols (III-V, VIII, IX, XIII) showed clear analgetic activity in the writhing syndrome inhibition test in mice; the 3-methoxy and 3-hydroxy compounds (V and XIII) were the most active ones, the latter being slightly more active than tramadol (I).
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Su, Feng, Guangtao Xu, Zhenhua Yao, Huachen Liu, and Yikun Chen. "First-Principles Calculations of Y-Si-O Nanoclusters and Effect of Si on Microstructure and Mechanical Properties of 12Cr ODS Steel in Vacuum Sintering System." Metals 12, no. 1 (January 15, 2022): 155. http://dx.doi.org/10.3390/met12010155.

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High density of thermally stable Y-Si-O nanoparticles dispersed in the Fe matrix play a primary role in oxide dispersion strengthened (ODS) steel. In this study, the binding energies of solutes Y, O and Si with vacancies have been calculated in the framework of first-principles density functional theory. According to the calculations, any two solutes of Y, O and Si bound with each other strongly in the second nearest neighboring (NN) sites while not in 1NN. A vacancy (v) bounds strongly with Y and O in 1NN site. The binding sequence of solutes with v followed O-v → Y-v → Si-v, and the affinity of Y, Si and v with O followed O-Y → O-v → O-Si. The nucleation mechanism of Y-O-Si nanoclusters was determined, which gave the feasibility of adding Si to ODS steels. The core (consisting of Si and O)-shell (enriched Fe and Cr) structure of the microparticles was found in ODS steels containing Si, fabricated by mechanical alloying (MA) and vacuum sintering. Moreover the nanoparticles of monoclinic cubic Y2O3, Y2SiO5 and Y2Si2O7 with sizes of 5~12 nm were observed in ODS steel. Si reduced the sintering temperature by maximizing densities and mechanical properties at a lower sintering temperature. The steel with 3 wt% Si was sintered at 1280 °C, exhibiting the best comprehensive mechanical properties. The tensile strength, hardness and relative density were 1025 MPa, 442.44 HV and 95.3%, respectively.
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Osipov, Artem A., Alina E. Gagaeva, Anastasiya B. Speshilova, Armenak A. Osipov, and Sergey E. Alexandrov. "OES diagnostics of NF3/Xe plasma for deep structures in LiNbO3." Journal of Physics: Conference Series 2388, no. 1 (December 1, 2022): 012081. http://dx.doi.org/10.1088/1742-6596/2388/1/012081.

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Abstract In this work, in situ non-perturbing method of optical emission spectroscopy is used to examine the features of the emission spectra of NF3/Xe plasma, which can be used for the process of continuous plasma-chemical etching of lithium niobate. To understand the physicochemical processes occurring in plasma, the influence of high-frequency power, pressure in the chamber, bias voltage and substrate temperature on the emission intensities of the F, N, Xe lines was studied. It was determined that increasing the bias voltage from -300 to -50 V and the temperature from 50 to 300°C doesn’t change the relative intensities of the analysed spectral lines, while increasing the high-frequency power from 500 to 750W and decreasing the pressure from 1.95 to 0.95Pa increase the intensities of the F, N, Xe lines.
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21

Regan, Meredith M., Samuel M. Niman, Gini F. Fleming, Barbara Walley, Giuseppe Viale, Beat J. K. Thurlimann, Sherene Loi, Marco Colleoni, Olivia Pagani, and Prudence A. Francis. "Historical early treatment effects of adjuvant endocrine therapy for breast cancer in high-risk subgroups: Reanalysis of BIG 1-98, SOFT and TEXT." Journal of Clinical Oncology 40, no. 16_suppl (June 1, 2022): 508. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.508.

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508 Background: Clinical trials testing adjuvant endocrine therapy (ET) have not historically limited enrollment to patients with clinically high-risk breast cancer (BC), nor estimated treatment (trt) effects prior to 5 yrs. In light of recent trial results for adjuvant CDK4/6 inhibitors, we estimated early relative and absolute trt effects of aromatase inhibitor (AI) vs tamoxifen (T), with ovarian suppression (OFS) if premenopausal, in high risk subgroups. Methods: From pts enrolled in adjuvant phase 3 randomized clinical trials BIG 1-98 (postmenopausal, 5yr AI v T), TEXT (5yr AI+OFS v T+OFS) and SOFT (5yr AI+OFS v T+OFS v T), we identified subgroups with HR+/HER2- BC and high risk features (≥4 pLN; or 1-3 pLN with grade 3, pT≥5 cm and/or Ki-67≥20% [retrospectively centrally assessed]). TEXT randomized at start of adjuvant trt; BIG 1-98 and SOFT after chemotherapy. Disease-free survival (DFS) was defined from randomization to invasive recurrence at local, regional, distant or contralateral breast, second non-breast malignancy or death. We estimated trt effects as differences in 2, 3 and 5yr DFS Kaplan-Meier estimates (KM diffs at t yrs) and hazard ratios over time intervals of 0-2, 0-3 and 0-5 yrs (HRs over 0 to t yrs) to approximate the maturity of trial results with increasing follow-up. Results: The high-risk HR+/HER2- subgroups were 695/4922, 707/2660 and 526/3047 pts in BIG 1-98, TEXT and SOFT with 202, 122, 142 DFS events observed by 5 yrs since randomization. 60%, 46% and 44% of pts had ≥4 pLNs; 42%, 90% and 92% had chemotherapy. The table summarizes results. Conclusions: In re-analysis of clinical high risk HR+/HER2- subgroups of 3 trials each ̃700 pts, 5 yrs AI vs T had similar magnitude of early trt effects after 2-3 yrs follow-up of all pts vs trt effects observed after 27 mos median follow-up in monarchE trial (HR=0.70; KM diffs 2.7% at 2 yrs, 5.4% at 3 yrs; n=5637). Relative and absolute trt effects sometimes diminished when estimated over 5 yrs rather than over 2 yrs, but meaningful absolute differences remained at 5 yrs in contrast to Penelope-B trial results. Design and interpretation of high risk HR+/HER2- early BC trials may depend on timing of randomization and selection of backbone adjuvant trts; follow-up >5 yrs must remain standard. [Table: see text]
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Dupre, Derrick A., Raj Nangunoori, Sravanthi Koduri, Cindy Angle, Diane Cantella, and Donald Whiting. "Disease Stabilization of DYT1-Positive Primary Generalized Dystonia With Deep Brain Stimulation of the Globus Pallidus Interna: A 15-Year Follow-up." Operative Neurosurgery 14, no. 5 (June 6, 2017): E53—E57. http://dx.doi.org/10.1093/ons/opx137.

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Abstract BACKGROUND AND IMPORTANCE Primary generalized dystonia (PGD) is a genetic form of dystonia that frequently displays pharmacological resistance and progresses quickly after onset. Deep brain stimulation (DBS) has been used successfully to treat refractory dystonia, specifically globus pallidus interna (GPi) DBS for DYT1-positive PGD patients. Long-term follow-up of the safety and efficacy falls short of the longevity seen in other diseases treated with DBS. CASE PRESENTATION A male patient presented for neurosurgical evaluation with scapular winging, hand contractures, and violent truncal spasms, which forced him to be bedridden. After failing conservative therapy, the 18-yr-old patient was implanted with bilateral GPi-DBS. DBS parameter adjustments were made primarily within the first 3 yr after implantation, with nominal changes thereafter. Initial settings were contact of 3 + 0−, amplitude of 4.9 V, frequency of 185 Hz, and pulse width of 270 μsec on the left and 3 + 0−, 2.8 V, 185 Hz, and 120 μsec on the right. Current settings are 3 + 2 + 1−, 5.2 V, 130 Hz, 330 μsec on the left and 3 + 0−, 3.5 V, 185 Hz, and 180 μsec on the right and have been relatively unchanged in the past 4 yr. Unified dystonia rating scale scores reveal a significant decrease in dystonic symptoms. CONCLUSION While prior reports have shown that GPi-DBS is effective for dystonia, this is the first with 15 yr of long-term follow-up showing disease stabilization, suggesting that stimulation is efficacious and can potentially prevent disease progression. This report reaffirms previous reports that recommend early surgical intervention before the onset of permanent musculoskeletal deficits.
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Adamiak-Giera, Urszula, Wojciech Jawień, Anna Pierzchlińska, Monika Białecka, Jan Dariusz Kobierski, Tomasz Janus, and Barbara Gawrońska-Szklarz. "Pharmacokinetics of Levodopa and 3-O-Methyldopa in Parkinsonian Patients Treated with Levodopa and Ropinirole and in Patients with Motor Complications." Pharmaceutics 13, no. 9 (September 3, 2021): 1395. http://dx.doi.org/10.3390/pharmaceutics13091395.

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Parkinson’s disease (PD) is a progressive, neurodegenerative disorder primarily affecting dopaminergic neuronal systems, with impaired motor function as a consequence. The most effective treatment for PD remains the administration of oral levodopa (LD). Long-term LD treatment is frequently associated with motor fluctuations and dyskinesias, which exert a serious impact on a patient’s quality of life. The aim of our study was to determine the pharmacokinetics of LD: used as monotherapy or in combination with ropinirole, in patients with advanced PD. Furthermore, an effect of ropinirole on the pharmacokinetics of 3-OMD (a major LD metabolite) was assessed. We also investigated the correlation between the pharmacokinetic parameters of LD and 3-OMD and the occurrence of motor complications. Twenty-seven patients with idiopathic PD participated in the study. Thirteen patients received both LD and ropinirole, and fourteen administered LD monotherapy. Among 27 patients, twelve experienced fluctuations and/or dyskinesias, whereas fifteen were free of motor complications. Inter- and intra-individual variation in the LD and 3-OMD concentrations were observed. There were no significant differences in the LD and 3-OMD concentrations between the patients treated with a combined therapy of LD and ropinirole, and LD monotherapy. There were no significant differences in the LD concentrations in patients with and without motor complications; however, plasma 3-OMD levels were significantly higher in patients with motor complications. A linear one-compartment pharmacokinetic model with the first-order absorption was adopted for LD and 3-OMD. Only mean exit (residence) time for 3-OMD was significantly shorter in patients treated with ropinirole. Lag time, V/F, CL/F and tmax of LD had significantly lower values in patients with motor complications. On the other hand, AUC were significantly higher in these patients, both for LD and 3-OMD. 3-OMD Cmax was significantly higher in patients with motor complications as well. Our results showed that ropinirole does not influence LD or 3-OMD concentrations. Higher 3-OMD levels play a role in inducing motor complications during long-term levodopa therapy.
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24

El Deeb, Sami, Adel Ehab Ibrahim, Ahmed Al-Harrasi, Gerhard Wolber, and Ronald Gust. "Validated Capillary Zone Electrophoresis Method for Impurity Profiling and Determination of NiII(3-OMe-Salophene)." Separations 9, no. 2 (January 21, 2022): 25. http://dx.doi.org/10.3390/separations9020025.

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A capillary zone electrophoresis method was developed for the determination of NiII(3-OMe-salophene), a substance with anticancer activity in vitro. A fused silica capillary (56 cm × 100 µm) was used for this purpose. The method was optimized in terms of parameters affecting the electrophoretic conditions in order to optimize separation efficiency and total time of migration. The analysis was best performed using an operating buffer of 50 mM borate, adjusted to pH 9.3, mixed with acetonitrile (50%, v/v) as organic modifier. Injections were performed hydrodynamically by applying a pressure of 50 mbar for 8 s, and a 30 kV separation voltage was selected at 25 °C. Detection was carried out at 250 nm using diode array detector (DAD). The method allowed the separation of NiII(3-OMe-salophene) from four other structurally related impurities in a total migration time (tm) of 8 min. Peak identification was achieved using the standard reference of individual impurities. The purity of the migrated NiII(3-OMe-salophene) was confirmed by Ultra-violet (UV) scan overlay depending on DAD. The linear ranges for the determination of NiII(3-OMe-salophene) was 400–20,000 ng mL−1 with limit of detection (LOD) of 120 ng mL−1. Acceptable intra-day and inter-day precisions were achieved (%relative standard deviation (RSD) results were less than 0.76% and 0.30%, respectively). The proposed method was assessed for greenness and compared to reported methodologies to prove superiority.
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25

Kohout, Ladislav. "The synthesis of 5,6-cyclopropanocholestanes with oxygen functions in positions 3 and 7." Collection of Czechoslovak Chemical Communications 51, no. 2 (1986): 429–35. http://dx.doi.org/10.1135/cccc19860429.

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The Simmons-Smith methylenation of the double bond in 3β-acetoxycholest-5-en-7-ols takes place selectively under formation of an adduct the configuration of which is determined by the configuration of the 7-hydroxyl group: 7β-alcohol IV gave 5β,6β-cyclopropane derivative VI, 7α-alcohol V gave 5α,6α-cyclopropane derivative VIII. On photochemically initiated cyclization of 3β-acetoxy-B-homo-5-en-7a-one (XIII) we obtained the product with an α-cyclopropane ring exclusively, i.e. 3β-acetoxy-5,6α-cyclopropano-5α-cholestan-7-one (XII).
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26

Quijije, Rina, Germania Vargas, Maria Elena Olaya Pincay, and Nancy Cando. "EVALUACIÓN DE ESTRÉS EN EL PERSONAL MÉDICO HOSPITALARIO ANTE EL COVID-19." Universidad Ciencia y Tecnología 24, no. 106 (November 16, 2020): 96–101. http://dx.doi.org/10.47460/uct.v24i106.401.

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La pandemia por COVID-19 ha desatado importantes situaciones en el mundo, entre las que se destacan los problemas económicos, problemas en el sector educativo y problemas en la comunidad médica, además de muchos otros. La responsabilidad de los especialistas de salud ante el COVID-19 ha implicadoque afronten situaciones de gran presión en el colectivo. Atender a pacientes infectados de COVID-19 implica riesgos significativos para el personal, tanto por la posibilidad latente de contagio como por el impacto emocional y en la salud mental de atender gran cantidad de enfermos y el manejo de un elevado número de fallecidos, lo que puede afectar considerablemente el estado físico, mental y emocional del especialista médico. Partiendo de estas premisas, se presenta en este trabajo un análisis de las emociones, valores y fortalezas morales del personal de salud, especialmente las enfermeras, en los centros de salud del Ecuador. Se pudo observar que las emociones negativas coexisten con importantes valores morales y fortalezas, que pueden ser condicionantes para el tratamiento médico y la atención a los enfermos. Palabras Clave: personal de salud, COVID-19, estrés laboral. Referencias [1]OMS, «Brote de enfermedad por coronavirus 2019,» Sitio web Mundial, 2019. [2]BONALIP, «Origen de la COVID,» 2020. [En línea]. Disponible: https://bolavip.com/otros/Animal-o-quimi-co-El-origen-del-Covid-19-20200406-0102.html. [Último acceso: 10 de Agosto 2020]. [3]A. Lozano, «Impacto de la epidemia del Coronavirus (COVID-19) en la salud mental del personal de salud y en la población general de China,» Revista de Neuro-Psiquiatría, vol. 83, nº 1, pp. 51-56, 2020. [4]SNGRE, «SITUACIÓN NACIONAL POR COVID-19(CORONAVIRUS),» Ecuador, 2020. [5]W. H. Organization, «sector salud - consejo,» World Health Organization , 2020. [6]N. Loncharich, «El cuidado enfermero,» Rev enferm Herediana., vol. 1, nº 1, p. 3, 2010. [7]O. M. d. l. Salud, «Directrices para ayudar a los países a mantener los servicios sanitarios esenciales durante la pandemia de COVID-19),» 2020. [8]J. De La Cruz, «Protegiendo al personal de la salud en la pandemia Covid-19,» Revista de la Facultad de Medicina Humana, vol. 20, nº 2, pp. 173-174, 2020. [9]F. Suarez y L. Rosales, «Algoritmos para la detección de estados emocionales,» UNEXPO Puerto Ordaz, Puerto Ordaz, 2020. [10]«Sentimiento,» Significados. com, 10 12 2019. [En línea]. Disponible: https://www.significados.com/sentimiento/. [Último acceso: 10 de Agosto 2020]. [11]M. Thomen Bastardas, «Psicología-Online,» Psicología-Online, 28 05 2019. [En línea]. Disponible: https://www.psicologia-online.com/que-son-los-sentimientoslista-tipos-y-ejemplos-4606.html. [Último acceso: 10 08 2020]. [12]N. Benito, M. Campos, S. Plaza, A. Sánchez y M. Carrasco, «El cuidado de las emociones en enfermería,» Revista de participación, investigación y documentación, p. Buenas prácticas, 2017. [13]A. Alvarado, «La ética del cuidado,» Aquichan, vol. 4, nº 1, pp. 30-39, 2004. [14]B. Hernández, F. Javier, V. Nava, L. Ramos y O. Medina, «¨El significado de cuidado en la práctica profesional de enfermería¨,» Aquichan, vol. 9, nº 2, pp.127-134, 2009. [15]Y. Naranjo Hernández, J. A. Concepción Pacheco y M. Rodríguez Larreynaga, «¨La teoría Déficit de autocuidado: Dorothea Elizabeth Orem.¨,» Gaceta MédicaEspirituana, vol. 19, nº 3, pp. 89-100, 2017. [16]Y. Naranjo, J. Concepción y M. Rodríguez, «La teoría Déficit de autocuidado: Dorothea Elizabeth Orem,» Gaceta Médica Espirituana, vol. 19, nº 3, 2017. [17]L. A. Prado Solar, M. González Reguera, N. Paz Gómez y K. Romero Borges, «La teoría Déficit de autocuidado: Dorothea Orem punto de partida para calidaden la atención,» Revista Médica Electrónica, vol. 36, nº6, pp. 835-845, 2014. [18]R. Paul, El conflicto de las interpretaciones, 2010 ed., F. d. C. Económica, Ed., México: Fondo de Cultura Económica, 2010. [19]I. d. P. y. S. M. M. (Madrid), «Cuidando la salud mental del personal sanitario,» Instituto de Psiquiatría y Salud Mental Marañón, Madrid, 2020. [20]S. E. d. Psiquiatría, «Cuidando la Salud Mental del Personal Sanitario,» Madrid, 2020.
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27

Bermejo García, Romualdo, and Laura San Martín Sánchez de Muniáin. "Del GATT a la Organización Mundial del Comercio: Análisis y perspectivas de futuro." Anuario Español de Derecho Internacional 12 (August 21, 2018): 147–200. http://dx.doi.org/10.15581/010.12.28547.

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INTRODUCCIÓN: CAUSAS, ORÍGENES Y OBJETIVOS DE LA RONDA URUGUAY DE NEGOCIACIONES COMERCIALES MULTILATERALES.- I. EL PROCESO DE NEGOCIACIÓN DE LA RONDA.- II. EL ACTA FINAL DE LA RONDA URUGUAY.- III. EL ACUERDO CONSTITUTIVO DE LA ORGANIZACIÓN MUNDIAL DEL COMERCIO COMO MARCO INSTITUCIONAL COMÚN. 1. Objetivos. 2. Funciones. 3. Personalidad jurídica de la OMC y el marco de cooperación internacional. 4. Estructura institucional. 5. La adopción de decisiones. 6. La aplicación por los Estados de las disposiciones de la OMC. 7. La OMC y sus Miembros: Continuidad con el GATT.- IV. EL NUEVO PROCEDIMIENTO DE SOLUCIÓN DE DIFERENCIAS: 1. El Organo de Solución de Diferencias. 2. La fase "pre-panel". 3. El procedimiento ante los grupos especiales. 4. La adopción de los informes por el OSD. El examen en apelación. 5. La aplicación de las recomendaciones del OSD. 6. El recurso al arbitraje.- V. LA TRANSICIÓN DEL GATT A LA OMC.- CONCLUSIONES.
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28

Sobolev, Victor S., Richard J. Cole, Joe W. Dorner, and Boris Yagen. "Isolation, Purification, and Liquid Chromatographic Determination of Stilbene Phytoalexins in Peanuts." Journal of AOAC INTERNATIONAL 78, no. 5 (September 1, 1995): 1177–82. http://dx.doi.org/10.1093/jaoac/78.5.1177.

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Abstract A liquid chromatographic (LC) method for determination of stilbene phytoalexins (SPs) in peanuts has been developed. SPs were extracted with acetonitrile–water (90 + 10, v/v) by high-speed blending. An aliquot of extract was applied to a minicolumn packed with AI2O3–ODS (C18) mixture and eluted with acetonitrile-water (90 + 10, v/v). Eluate was evaporated under nitrogen, and residue was dissolved in LC mobile phase. SPs in an aliquot of purified extract were quantitated by normal-phase partition LC on silica gel with n-heptane–2-propanol–water–acetonitrile–acetic acid (1050 + 270 + 17 + 5 + 1, v/v) as mobile phase. Recoveries of SPs [frans-4-(3-methyl-but-1-enyl)-3,5,4′-trihy-droxystilbene (trans-arachidin-3; t-Ar-3), trans-3-isopentadienyl-4,3′,5′-trihydroxystilbene (t-IPD), and trans-3,5,4′-trihydroxystilbene (trans-resveratrol; t-Res)] from peanuts spiked at 300 ppb were 96.05 ± 2.8%. Limits of quantitation for t-Ar-3 and t-IPD were about 100 ppb. t-Ar-3, t-IPD, and t-Res were found in all parts of the peanut plant as major SPs produced in response to fungal invasion.
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29

Sinchaiyakit, Puksiri, Yohji Ezure, Sarin Sriprang, Supakorn Pongbangpho, Nasapon Povichit, and Maitree Suttajit. "Tannins of Tamarind Seed Husk: Preparation, Structural Characterization, and Antioxidant Activities." Natural Product Communications 6, no. 6 (June 2011): 1934578X1100600. http://dx.doi.org/10.1177/1934578x1100600619.

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The high content (about 39%) of polymeric tannins in tamarind ( Tamarindus indica L.) seed husk (TSH) was demonstrated, and an extract (crude TSE) with a high content (about 94%) of polymeric tannins was prepared from TSH with a one pot extraction using ethanol/water (3:2, v/v). The crude TSE was further purified with Sephadex LH20 to give one fraction (metTSE) eluted with methanol/water (3:2, v/v) and another (acTSE) eluted with acetone/water (3:2, v/v). The tannins of acTSE were established as polymeric proanthocyanidins (PA) by 13C NMR spectroscopy; this was further confirmed by IR and UV spectroscopy, n-BuOH/HCl and vanillin assays, and from HPLC pattern. The ratio of procyanidins to prodelphinidins was 2:3, and the average degree of polymerization of acTSE was 7. Galloylated flavan-3-ols were not detected in acTSE. The main ingredients of metTSE were confirmed to be polymeric PA by 13C NMR spectroscopy. The antioxidant activities using DPPH and ABTS assays were investigated. The IC50 values of acTSE were 4.2±0.2 (DPPH assay) and 6.2±0.3 μg/mL (ABTS assay).
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30

Patil, Priyanka, Madhuree Gawhankar, Shivcharan Bidve, R. V. Gudi, and Atul Lavand. "PHYTOCHEMICAL AND ELEMENTAL PROFILING AND STANDARDIZATION OF SOME AYURVEDA MEDICINES USED IN COVID-19 PANDEMIC." International Journal of Research in Ayurveda and Pharmacy 12, no. 4 (August 28, 2021): 76–83. http://dx.doi.org/10.7897/2277-4343.1204110.

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Tribhuvankirti Rasa is a herbo-mineral Ayurvedic medicine regularly used to treat different types of fever. It has antipyretic and analgesic activities. It is an effective medicine for the common cold, flu and other Vata kapha problems. Laghumalini Vasanta is also Ayurvedic medicine, used to treat chronic fever and effective in pitta disorders. Ministry of AYUSH, Government of India also recommended these medicines to prevent the severe conditions of Cov-2 infection. Review of literature suggested that phytochemical and elemental characterization parameters of Tribhuvankirti Rasa and Laghumalini Vasant are not reported. The objective of this study is to report phytochemical and elemental profiling and to standardize Tribhuvankirti Rasa (TKR) and Laghumalini Vasant (LMV) to confirm quality and purity. Tribhuvankirti Rasa and Laghumalini Vasant evaluated for phytochemical and elemental parameters by HPTLC and ICP-OES respectively. HPTLC analysis confirms LMV contains Piperine and TKR contains Piperine and 6-Gingerol. The solvent systems toluene: ethyl acetate (7: 3) v/v for Piperine & Hexane: Ethyl acetate: Formic acid (4 : 6 : 0.1) v/v for 6-Gingerol were optimized. ICP-OES analysis confirms presence of Zn in LMV and Hg in TKR. HPTLC and ICP-OES methods were validated successfully for Tribhuvankirti Rasa and Laghumalini Vasant. The characterization and method validation parameters presented in this paper may serve as standard reference for quality control analysis of Tribhuvankirti Rasa and Laghumalini Vasant.
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Antolín, Raquel, Gregorio Borge, Tomás Posada, Juan C. Raposo, Iker Seara, and Néstor Etxebarria. "Inductively Coupled Plasma Compared with Direct Current Arc Spectrometry for Analysis of Minor Elements in Aluminium Baths." Journal of AOAC INTERNATIONAL 87, no. 5 (December 1, 2004): 1218–23. http://dx.doi.org/10.1093/jaoac/87.5.1218.

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Abstract A validation study was carried out in order to evaluate the efficiency of inductively coupled plasma-optical emission spectrometry (ICP-OES) for the analysis of minor elements (manganese, chromium, copper, iron, and titanium) in aluminium alloys. Aluminium casting samples were obtained by adding compressed powder compacts of each alloying element and aluminium (minitablets) to aluminum baths in a laboratory crucible furnace. Digestion of solid samples was performed using concentrated HCl and H2O2 35% (v/v) previous to analysis by ICP-OES without any matrix separation. This solution-based method was validated considering direct current arc spectrometry as the reference method based on direct analysis without any pretreatment of the solid samples considered. Univariate statistical procedures were carried out, for which precision &lt;3% and trueness of the analytical results were taken into account.
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32

Ghubayra, Reem, Rachel Hindle, Rana Yahya, Elena F. Kozhevnikova, and Ivan V. Kozhevnikov. "Aerobic Oxidative Desulfurization of Liquid Fuel Catalyzed by P–Mo–V Heteropoly Acids in the Presence of Aldehyde." Catalysts 11, no. 8 (August 18, 2021): 988. http://dx.doi.org/10.3390/catal11080988.

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Aerobic oxidative desulfurization (ODS) of model liquid fuel (dodecane spiked with dibenzothiophene (DBT)) was carried out in the presence of bulk and supported Keggin-type heteropoly acids H3+nPMo12-nVnO40 (HPA-n, n = 0–3) as heterogeneous catalysts and benzaldehyde as a sacrificial reductant. In the presence of bulk H4PMo11VO40 (HPA-1), 100% of DBT was removed from fuel (converted to DBT sulfone) at 60 °C and ambient air pressure. Multiple catalyst reuse without loss of activity was demonstrated. The ODS reaction was strongly inhibited by radical scavengers. An unbranched radical chain mechanism was proposed.
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Cândido, Duarte N. C., Marcio S. Rassi, Guilherme Henrique Weiler Ceccato, Jean Gonçalves de Oliveira, and Luis A. B. Borba. "Microsurgical Resection of Trigeminal Schwannomas: 3-Dimensional Operative Video." Operative Neurosurgery 18, no. 1 (May 23, 2019): E18. http://dx.doi.org/10.1093/ons/opz097.

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Abstract Trigeminal schwannomas are benign lesions arising from the Schwann cells of the trigeminal nerve. This is an unusual tumor that accounts for less than 0.4% of intracranial pathologies, even though they are the second most frequent schwannoma after the vestibular schwannoma. The tumor spreads along the natural course of the V nerve at its cisternal portion, along the ganglion inside Meckel's cave or through its peripheral division. Even though the tumor can reach great size and become multicompartmental. We present a 51-yr-old woman, with an history of 3 mo of incapacitating facial pain, that was found on examination to be on the territory of the third division of the trigeminal nerve on the right side. The MRI depicted a large homogeneous enhancing lesion at the base of the right middle fossa with extension through the petrous apex to the most superior and medial part of the posterior fossa. The patient was operated by the senior author, through a middle fossa approach, dissecting between the two layers of the middle fossa dura (the apparent inner and the true outer layer of the cavernous sinus), the so called middle fossa “peeling”. We achieved total resection of the tumor, but the patient presented after surgery with facial nerve paresis. This is thought to be related to geniculate ganglion manipulation, as it was unprotect by bone at the middle fossa and the patient maintained lacrimal function (post-geniculate alteration). It resolved completely after 6 mo. The patient consented to publication of her images.
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Barros, Elton Fernandes, Livian Isabel de Medeiros Carvalho, Itainar Henriques Carvalho, Amanda Pereira Ferraz, and Hellen Bandeira de Pontes Santos. "Sistemas de gradação histológica em queilites actínicas: revisão de literatura." ARCHIVES OF HEALTH INVESTIGATION 9, no. 6 (June 13, 2020): 582–86. http://dx.doi.org/10.21270/archi.v9i6.4898.

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Introdução: A queilite actínica (QA) é uma desordem potencialmente maligna associada à exposição crônica à luz solar como principal fator etiológico. A QA tem como principal sítio de acometimento o vermelhão do lábio inferior, apresentando características clínicas marcantes. Porém, a análise histopatológica desta lesão merece um enfoque especial pelas características bastante expressivas para o potencial de malignidade. Assim, para essa análise, são elencados dois sistemas principais: o sistema da Organização Mundial da Saúde (OMS), e o binário. Objetivo: Realizar uma revisão da literatura para demonstrar os pontos avaliados e o valor preditivo dos sistemas de gradação histológica em QA. Metodologia: Trata-se de um estudo de revisão bibliográfica, utilizando artigos da base de dados da SCIELO e PUBMED, encontrados com o uso dos descritores: “actinic cheilitis”, “WHO system”, “binary system”, “oral potentially malignant disorders”, “histological features in actinic cheilitis”, fazendo uso do operador booleano “AND”. Conclusão: Diante da revisão realizada, percebeu-se a importância da adoção dos sistemas de gradação histológica da OMS, e o binário para uma análise minuciosa de lesões de QA, que apresentam potencial de malignidade. Ademais, constatou-se o favorecimento do sistema binário na redução da subjetividade entre os patologistas quanto à gradação das avaliações histopatológicas. Descritores: Queilite; Patologia Bucal; Neoplasias Labiais; Classificação; Diagnóstico. Referências Lopes MLDS, Silva Junior FLS, Lima KC, Oliveira PT, Silveira EJD. Clinicopathological profile and management of 161 cases of actinic cheilitis. An Bras Dermatol. 2015;90(4):347-50. Arnaud RR, Soares MSM, Paiva MAF, Figueiredo CRLV, Santos MGC, Lira CC. Queilite actínica: avaliação histopatológica de 44 casos. Rev Odontol UNESP. 2014;43(6):384-89. Pilati S, Bianco BC, Vieira D, Modolo F. Histopathologic features in actinic cheilitis by the comparison of grading dysplasia systems. Oral Dis. 2017 Mar;23(2):219-224. Pilati S, Bianco BC, Vieira D, Modolo F. Histopathologic features in actinic cheilitis by the comparison of grading dysplasia systems. Oral Dis. 2017;23(2):219-24. Maia HCM, Pinto ANS, Pereira JS, Medeiros AMC, Silveira EJD, Miguel MCC. Lesões orais potencialmente malignas: correlações clínico-patológicas. Einstein. 2016;14(1): 35-40. Savage NW, McKay C, Faulkner C. Actinic cheilitis in dental practice. Aust Dent J. 2010; 55(Suppl 1):78-84. Vieira RA, Minicucci EM, Marques ME, Marques SA. Actinic cheilitis and squamous cell carcinoma of the lip: clinical, histopathological and immunogenetic aspects. An Bras Dermatol. 2012; 87(1):105-14. Dancyger A, Heard V, Huang B, Suley C, Tang D, Ariyawardana A. Malignant transformation of actinic cheilitis: A systematic review of observational studies. J Investig Clin Dent. 2018; 9(4):e12343. de Santana Sarmento DJ, da Costa Miguel MC, Queiroz LM, Godoy GP, da Silveira EJ. Actinic cheilitis: clinicopathologic profile and association with degree of dysplasia. Int J Dermatol. 2014; 53(4):466-72. Wood NH, Khammissa R, Meyerov R, Lemmer J, Feller L. Actinic cheilitis: a case report and a review of the literature. Eur J Dent. 2011; 5(1):101-6. Mello FW, Melo G, Modolo F, Rivero ER. Actinic cheilitis and lip squamous cell carcinoma: Literature review and new data from Brazil. J Clin Exp Dent. 2019;11(1):e62-9. Warnakulasuriya S, Johnson NW, van der Waal I. Nomenclature and classification of potentially malignant disorders of the oral mucosa. J Oral Pathol Med. 2007;36(10):575-80. Paiva MAF, Soares MSM, Figueiredo CRLV, Luna AH, Oliveira VEN, Brasil Júnior O. Associação entre displasia e inflamação em queilite actínica. J Bras Patol Med Lab. 2012; 48(6):455-58. Warnakulasuriya S, Reibel J, Bouquot J, Dabelsteen E. Oral epithelial dysplasia classification systems: predictive value, utility, weaknesses and scope for improvement. J Oral Pathol Med. 2008;37(3):127-33. Câmara PR, Dutra SN, Takahama Júnior A, Fontes K, Azevedo RS. A comparative study using WHO and binary oral epithelial dysplasia grading systems in actinic cheilitis. Oral Dis. 2016; 22(6):523-9. Kujan O, Oliver RJ, Khattab A, Roberts SA, Thakker N, Sloan P. Evaluation of a new binary system of grading oral epithelial dysplasia for prediction of malignant transformation. Oral Oncol. 2006;42(10):987-93. Nagata G, Santana T, Queiroz A, Caramez RH, Trierveiler M. Evaluation of epithelial dysplasia adjacent to lip squamous cell carcinoma indicates that the degree of dysplasia is not associated with the occurrence of invasive carcinoma in this site. J Cutan Pathol. 2018. doi: 10.1111/cup.13270. Mello FW, Miguel AFP, Dutra KL, Porporatti AL, Warnakulasuriya S, Guerra ENS, Rivero ERC. Prevalence of oral potentially malignant disorders: A systematic review and meta-analysis. J Oral Pathol Med. 2018;47(7):633-40. Izumo T. Oral premalignant lesions: from the pathological viewpoint. Int J Clin Oncol. 2011;16(1):15-26. Kujan O, Khattab A, Oliver RJ, Roberts SA, Thakker N, Sloan P. Why oral histopathology suffers inter-observer variability on grading oral epithelial dysplasia: an attempt to understand the sources of variation. Oral Oncol. 2007; 43(3):224-31. El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ. World Health Organization Classification of Head and Neck Tumours. WHO/IARC Classification of Tumours 2017; 4th ed. Lyon, France: IARC Press. R SA, B N P, Hegde U, K U, G S, G K, Sil S. Inter- and Intra-Observer Variability in Diagnosis of Oral Dysplasia. Asian Pac J Cancer Prev. 2017;18(12):3251-54. Olinici D, Cotrutz CE, Mihali CV, Grecu VB, Botez EA, Stoica L, Onofrei P, Condurache O, Dimitriu DC. The ultrastructural features of the premalignant oral lesions. Rom J Morphol Embryol. 2018;59(1):243-48.
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Čejka, Jan, Richard Kubík, Bohumil Kratochvíl, and Josef Kuthan. "Sterically Crowded Heterocycles. VI. Relative Configuration of Diastereoisomeric (Z)-1,3-Diphenyl-3-(5-methyl-2-phenylimidazo[1,2-a]pyridin-3-yl)prop-2-en-1-ols." Collection of Czechoslovak Chemical Communications 61, no. 9 (1996): 1380–85. http://dx.doi.org/10.1135/cccc19961380.

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Relative configuration of the titled racemic compounds 1a and 1b has been elucidated on the basis of a complete X-ray structure determined for the higher melting diastereoisomer. The compound 1a crystallizes in the orthorhombic space group P21212, a = 15.610(3) Å, b = 18.634(4) Å, c = 7.5672(7) Å, V = 2201.1(6) Å3, Z = 4. Preparative separation of both diastereoisomers is reported.
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Gonzalez Garcia, Walter Adalberto, Andrea Michelle Prado Matamoros, Karla Gisella Velasquez Paccha, and Fanny Concepcion Suarez Camacho. "Cardiometabolic risk in students of the nutrition and dietetics career." Universidad Ciencia y Tecnología 25, no. 111 (December 12, 2021): 174–82. http://dx.doi.org/10.47460/uct.v25i111.528.

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The cardiometabolic risk describes the probabilities of a person to suffer a heart or blood vessels damages. Hence the relevance of determining this type of risk in the students of the Nutrition and Dietetics career of the Technical University of Babahoyo. For this purpose, indicators such as waist circumference, waist/height formula, sex, body mass index, waist-height index ICE, physical activity and inductive-deductive method were measured in a population of 100 students. It was found that the predominant nutritional status in female students is overweight and obesity. This indicates that 29% of female students have an increased cardiovascular risk. With regard to cardiometabolic risk, it was determined that female students had a rate of 36%, compared with male students with 11%. Keywords: cardiometabolic risk factors, overweight, obesity. References [1]Organización Mundial de la Salud, «www.who.int. Non communicable diseases,» 2018. [Online]. Available: https://www.who.int/es/news-room/fact-sheets/detail/non-communicable-diseases. [Last access: August 25, 2021]. [2]J. Maldonado, C. Carranza, M. Ortiz, C. Gómez and N.Cortés, «Prevalencia de factores de riesgo caardiometabólico en estudiantes de la Universidad de la región centroocidental en la Universidad Michoacana San Nicolás de Hidalgo. México,» SCIELO, vol. 24, nº 2, pp. 78-86, 2013. [3]M. Morales, «Influence of phisical activity and nutritional habits on the risk of metabolic syndrome,» SCIELO, vol. 6, 2016. [4]G. Morales, T. Castillo, S. Muñoz, C. Belma, A. Soto, I. Schifferli and F. Guillén, «Asociación entre factores de riesgo cardiometabólicos, actividad física y sedentarismo, » Nutrición Hospitalaria, vol. 34, nº 6, pp. 1345-1352, 2017. [5]Organización Mundial de la Salud, «Obesidad y sobrepeso,» 2021. [Online]. Available: https://www.who.int/es/news-room/fact-sheets/detail/obesity-and-overweight. [Last access: August 29, 2021]. [6]G. Bray, G. Fruhbeck, D. Ryan and J. Wilding, «Management of obesity,» Lancet, vol. 387, nº 7, pp. 1847-1956, 2016. [7]A. Caicedo Paliz, A. León Fierro and K. Zambrano Llaguno, Protocolo de diagnóstico y manejo multidisciplinario de pacientes con sobrepeso y obesidad en la consulta ambulatoria, Quito: Universidad San Francisco de Quito, 2021. [8]INEC, «Encuesta Nacional de Salud y Nutrición (ENSANUT),» INEC, Quito, 2018. [9]N. Britto Núñez and R. Alcázar Carett, «Obesidad y riesgo cardiometabólico. Revisión.,» CIMEL, vol. 16, nº 2, pp. 106-113, 2011. [10]J. Vandervelde, H. Savelberg, N. Schaper and A. Koster, «Moderate activity and fitness not sedentary time are independently associated with cardiometabolic risks in US adults aged 18-49,» Environ Resident Public Health, vol. 12, pp. 2330-2343, 2015. [11]V. Carson and I. Janssen, «Volume, patterns and types of sedentary behavior and cardiometabolic health children and adolescents: a cross sectional study,» BMC Public Health, vol. 186, pp. 186-195, 2011. [12] T. Rendo Urteaga, A. De Moraes, T. Callesse y T. Marrios, «The combined effect of physical activity and sedentary behaviors on a clustered cardiometabolic risks score. The Helena Study,» Internal Cardiology, vol. 186, pp. 186-195, 2015. [13]R. Monroy Torres, C. Aguiklera Juarez and J. Nares, «Riesgo cardiometabólico en adolescentes con y sin obesidad: variables metabólicas, nutricionales y consumo de refresco,» revista Mexicana de trastornos Alimentarios, vol. 9, nº 1, pp. 24-33, 2018. [14]OMS, «estrategia Mundial sobre el régimen alimentario, actividad física y salud,» 2017. [Online]. Available: https://www.who.int/diethysicactivity/pa/es.[Last access: August 30, 2021]. [15]A. Alvarado Sánchez, A. González Yebra and M. Macías, «Correlaciones de factores de riesgo cardiometabólicio e hipoactividad con indice corporal y circunferencia de cintura en trabajadores del sector cuero y calzado de la ciudad de León,» Jóvenes en la ciencia, vol. 3, nº 2, pp. 1-5, 2017. [16]SEEDO, «Consenso SEEDO para la evaluación del sobrepeso y la obesidad. Revista Española de Obesidad, » 2007. [Online]. Available: https://www.seedo.es/images/site/documentacionConsenso/Consenso_SEEDO_2007 pdf. [Last access: August 21, 2021].
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Moraes, Isadora Magno, Nívia Magalhães da Silva Freitas, Erllon Rodolfo Viegas Barata, and Nadia Magalhães da Silva Freitas. "Formação de professores e os direitos humanos: interrogando a violência contra a mulher (Teacher training and human rights: interrogating violence against women)." Revista Eletrônica de Educação 15 (February 28, 2021): e4519020. http://dx.doi.org/10.14244/198271994519.

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e4519020The mark of violence is present in today's society. It is in this context that human rights education is fundamental. The research, of qualitative nature, aimed to apprehend and analyze, in compliance with human rights, the problematized aspects with regard to violence against women, supporting on the structured interview, projective modality, which used the device of photo reproduction so that the interviewees could talk, critically, about what they saw. For discussion, two textual productions related to the reading of two reproductions that “spoke” of violence against women, were considered and submitted to interpretative analysis. The texts expressed contradiction to what was put in the photo reproduction, problematizing the violations of rights and, at the same time, considering ethics, values, and human rights as fundamental components to the exercise of citizenship and, still, evoking the dignity of the human person for the constitution of scenarios sensitive to humanity.ResumoA marca da violência está presente na atual sociedade. É nessa conjuntura que a educação em direitos humanos se mostra fundamental. A pesquisa, de cunho qualitativo, buscou apreender e analisar, na observância aos direitos humanos, os aspectos problematizados no tocante à violência contra a mulher, apoiando-se na entrevista estruturada, modalidade projetiva, que utilizou o dispositivo de foto reprodução para que os entrevistados discorressem, criticamente, sobre o que viam. Trouxemos para a discussão duas produções textuais relativas à leitura de duas fotos reproduções que “falavam” da violência contra a mulher, as quais foram submetidas à análise interpretativa. Os textos expressavam contrariedade ao que estava posto nas fotos reproduções, problematizando as violações dos direitos e, ao mesmo tempo, considerando a ética, os valores e os direitos humanos como componentes fundamentais ao exercício da cidadania; e, ainda, evocando a dignidade da pessoa humana para a constituição de cenários sensíveis à humanidade.ResumenLa marca de la violencia está presente en la sociedad actual. Es en este momento que la educación en derechos humanos es fundamental. La investigación, de carácter cualitativo, buscó aprehender y analizar, en cumplimiento de los derechos humanos, los aspectos problematizados en torno a la violencia contra las mujeres, basándose en la entrevista estructurada, la modalidad proyectiva, que utilizó el dispositivo fotorreproducción para que los entrevistados hablaran, críticamente, de lo que vieron. Trajimos la discusión de las producciones textuales relacionadas con la lectura de dos fotorreproducción que "hablaban" de la violencia contra la mujer, que fueron sometidas a un análisis interpretativo. Los textos expresaron contradicción con lo que se puso en las fotoreproducciones, problematizando las violaciones de los derechos y, al mismo tiempo, considerando la ética, los valores y los derechos humanos como componentes fundamentales para el ejercicio de la ciudadanía y, aún, evocando la dignidad de la persona humana para la constitución de escenarios sensibles a la humanidad.Palavras-chave: Formação de professores, Educação em direitos humanos, Violência contra a mulher.Keywords: Teacher training, Human rights education, Violence against women.Palabras claves: Formación de profesores, Educación en derechos humanos, La violencia contra las mujeres.ReferencesAFONSO, Maria Rosa. Trabalhar os direitos humanos no contexto escolar: da compreensão aos instrumentos. Lisboa: DGIDC/ME, 2005. Disponível em: http://www.dhnet.org.br/dados/livros/edh/portugal/rosa_afonso/livro_rosa_afonso.pdf. Acesso em: 20 dez. 2018.ARAÚJO, Aline Soares Storch de; AFONSO, Maria Lúcia Miranda. A educação em direitos humanos na educação infantil: formação de sujeitos de direitos. Revista Eletrônica de Educação, São Carlos, v. 12, n. 1, p. 46-60, 2018. Disponível em: http://www.reveduc.ufscar.br/index.php/reveduc/article/view/1887/667. Acesso em: 28 jun. 2020.AWAD, Fahd. O princípio constitucional da dignidade da pessoa humana. Justiça do Direito, Passo Fundo, v. 20, n. 1, p. 111-120, 2006. Disponível em: http://seer.upf.br/index.php/rjd/article/view/2182. Acesso em: 22 nov. 2019.BASÍLIO, Ana Luiza. 5 escolas combatem a violência contra as mulheres. 2017. Carta Capital online, de 30 de março de 2020. Disponível em: https://www.cartacapital.com.br/educacao/5-escolas-combatem-violencia-contra-as-mulheres/. Acesso em: 30 mar. 2020.BRASIL. Câmara dos Deputados. Comissão de Defesa dos Direitos da Mulher. Mapa de violência contra a mulher 2018. Brasília: Câmara dos Deputados 55ª legislatura-4ª sessão legislativa, Comissão de Defesa dos Direitos da Mulher, 2018a. Disponível em: https://www2.camara.leg.br/atividade-legislativa/comissoes/comissoes-permanentes/comissao-de-defesa-dos-direitos-da-mulher-cmulher/arquivos-de-audio-e-video/MapadaViolenciaatualizado200219.pdf. Acesso em: 15 jan. 2020.BRASIL. Fórum Brasileiro de Segurança Pública. Anuário brasileiro de segurança pública. São Paulo: Fórum Brasileiro de Segurança Pública. 2018b. Disponível em: http://www.forumseguranca.org.br/wp-content/uploads/2019/03/Anuario-Brasileiro-de-Seguran%C3%A7a-P%C3%BAblica-2018.pdf. Acesso em: 15 dez. 2019.BRASIL. Ministério da Educação. Base Nacional Comum Curricular. Ministério da Educação, Brasília, DF: MEC, 2017. Disponível em: http://basenacionalcomum.mec.gov.br/ . Acesso em: 20 nov. 2019.BRASIL. Ministério da Educação, Secretaria de Educação Básica. Programa Ética e Cidadania. Construindo valores na escola e na sociedade: inclusão e exclusão social. Módulo 3: Direitos Humanos. Brasília: Ministério da Educação, Secretaria de Educação Básica. 2007. Disponível em: http://portal.mec.gov.br/seb/arquivos/pdf/Etica/3_fasc_direitos_humanos.pdf. Acesso em 8 de jan. 2020.BRASIL. Ministério dos Direitos Humanos. A Declaração Universal dos Direitos Humanos e os Objetivos de Desenvolvimento Sustentável: avanços e desafios. Brasília: Ministério dos Direitos Humanos, 2018c. Disponível em: https://www.sdg16hub.org/system/files/2018-12/Cartilha%20DUDH%20e%20ODS%20%281%29_1.pdf.Acesso em: 15 dez. 2019.BRASIL. Organização das Nações Unidas. Brasil. Direitos Humanos das Mulheres. 2018d. Disponível em: https://nacoesunidas.org/wp-content/uploads/2018/08/Position-Paper-Direitos-Humanos-das-Mulheres.pdf. Acesso em: 10 dez. 2019.BRASIL. Presidência da República. Brasil. 2006. Lei n. 11.340, de 7 de agosto, de 2006. Disponível em: http://www.planalto.gov.br/ccivil_03/_Ato2004-2006/2006/Lei/L11340.htm. Acesso em: 20 fev. 2020.BRASIL. Presidência da República. 2015. Lei n. 13.104, de março de 2015. Disponível em: http://www.planalto.gov.br/CCIVIL_03/_Ato2015-2018/2015/Lei/L13104.htm. Acesso em: 20 jan. 2020.BRASIL. UNESCO. Declaração Universal dos Direitos Humanos. 1998. Brasília: UNESCO do Brasil, 1998. Disponível em: https://nacoesunidas.org/wp-content/uploads/2018/10/DUDH.pdf. Acesso em: 20 nov. 2019.CANDAU, Vera Maria Ferrão. Educação em direitos humanos: principais desafios. Rio de Janeiro: mímeo, 2005.CANDAU, Vera Maria Ferrão et al. (A) educador(a) como agente sociocultural e político. In: CANDAU, Vera Maria Ferrão et al. Educação em direitos humanos e formação de professores. São Paulo: Cortez, 2013. p. 33-53.CANDAU, Vera Maria Ferrão; SACAVINO, Susana Beatriz. Educação em direitos humanos e formação de educadores. Educação, Porto Alegre, v. 36, n. 1, p. 59-66, 2013. Disponível em: http://revistaseletronicas.pucrs.br/ojs/index.php/faced/article/viewFile/12319/8741. Acesso em: 10 jan. 2020.CULAU, Julia; LIRA, Diana; SPONCHIADO, Denise Aparecida Martins. Educação em direitos humanos: um desafio da sociedade e da escola. EDUCERE. Congresso Nacional de Educação, 12. Curitiba, Paraná, 2015. Anais eletrônico... Disponível em: https://educere.bruc.com.br/arquivo/pdf2015/18221_7983.pdf. Acesso em: 24 out. 2020.CRESWEEL, John W. Investigação qualitativa e projeto de pesquisa: escolhendo entre cinco abordagens. Porto Alegre: Penso, 2014.FERNANDES, Angela Viana Machado; PALUDETO, Melina Casari. Educação e direitos humanos: desafios para a escola contemporânea. Cadernos Cedes, Campinas, v. 30, n. 81, p. 233-249, 2010.FREITAS, Nívia Magalhães da Silva et al. Conflitivas sociocientíficas no ensino de ciências: proposições ao biodireito e a dignidade humana. Revista Brasileira de Ensino de Ciências e Tecnologia, Ponta Grossa, v. 12, n. 3, p. 187-201, 2019.FREITAS NETO, José de. Sobre violências e direitos humanos: o papel da educação em tempos sombrios. 2007. Jornal da UNICAMP. Disponível em: https:// www.unicamp.br/index.php/ju/artigo/jose-alves-de-freitas-neto/sobre-violencias-e-direitos-humanos-o-papel-da-educação-em. Acesso em: 15 dez. 2019.GORCZEVSKI, Clovis. A educação e o plano nacional de educação em direitos humanos: efetivando os direitos fundamentais no Brasil. Revista do Direito, Santa Cruz do Sul, v. 39, p. 18-42, 2013. Disponível em: https://online.unisc.br/seer/index.php/direito/article/view/3550/2699. Acesso em: 10 dez. 2019.GUIMARAES, Maisa Campos; PEDROZA, Regina Lucia Sucupira Violência contra a mulher: problematizando definições teóricas, filosóficas e jurídicas. Psicologia Sociedade, Belo horizonte, v. 27, p. 256-266, 2015. Disponível em: http://www.scielo.br/pdf/psoc/v27n2/1807-0310-psoc-27-02-00256.pdf. Acesso em: 10 mar. 2020.KRUG, Etienne G. et al. World report on violence and health. Lancet, Reino Unido, v. 360, n. 5, p. 1083-1088, 2002 Disponível em: https://www.researchgate.net/publication/282096365_World_Report_on_Violence_Health Acesso em: 10 dez. 2019.MARSHALL, T. H. Cidadania, classe social e status. Rio de Janeiro: Zahar, 1967.MINAYO, M. C. de. S. Trabalho de campo: contexto de observação, interação e descoberta. In: MINAYO, M. C. de. S. (Org.); DELAN DES, S. F.; GOMES, R. Pesquisa social: teoria, método e criatividade. Petrópolis, RJ: Vozes, 2016. p. 56-71. (Série Manuais Acadêmicos).MOEHLECKE, Sabrina. Por uma cultura de Educação em direitos humanos. In: ASSIS, Simone Gonçalves de; COSTANTINO, Patrícia; AVANCI, Joviana Quintes (Org.). Impactos da violência na escola: um diálogo com professores. Rio de Janeiro: Ministério da Educação; Editora FIOCRUZ, 2010. p. 18-39. Disponível em: http://books.scielo.org/id/szv5t/pdf/assis-9788575413302.pdf. Acesso em 10 mar. 2020.MUSEGANTE, Maria Laura de Lima. Humanização na educação básica, a contribuição dos direitos humanos revista brasileira de educação básica. Revista Brasileira de Educação Básica, Minas Gerais, v. 4, p. 1-8, 2019. Disponível em: http://rbeducacaobasica.com.br/humanizacao-na-educacao-basica/.Acesso em 15 out. 2019. OLIVEIRA, Fabiana Santos et al. Violência doméstica contra a mulher: uma análise a partir do relato de casos. Revista Médica de Minas Gerais, Minas Gerais, v. 26, supl. 8, p. 443-449. Disponível em: http://www.rmmg.org/artigo/detalhes/2195. Acesso em: 16 jan. 2016.OLIVEIRA, Roberto Dalmo Varalho Lima de. Educação em ciências e direitos humanos: algumas percepções e uma luta constante. In: OLIVEIRA, Roberto Dalmo Varalho Lima de; QUEIROZ, Gloria Regina Pessoa. Educação em Ciências e Direitos Humanos: reflexão-ação em/para uma sociedade plural. Rio de Janeiro: Multifoco, 2013. p. 19-40OLIVEIRA, Roberto Dalmo Varalho Lima de; QUEIROZ, Gloria Regina Pessoa. O cotidiano, o contexto e a educação em direitos humanos: a escolha de um caminho para a Educação cidadã cosmopolita. Revista Ibero-Americana de Educación, España, v. 71, n. p. 75-96, 2016. Disponível em: https://rieoei.org/RIE/article/view/49. Acesso em: 8 de jan. 2020.Organização Pan-Americana da Saúde; Organização Mundial da Saúde. Violência contra a mulher. Estratégia e plano de ação para o reforço do sistema de saúde para abordar a violência contra a mulher. Washington, D.C., EUA: 54° Conselho Diretor; 67ª Sessão do Comitê Regional da OMS para as Américas, 2015. Disponível em: http://iris.paho.org/xmlui/bitstream/handle/123456789/18386/CD549Rev2_por.pdf?sequence=9isAllowed=y. Acesso em: 15 dez. 2019.PEREIRA, Tatiana Koschelny. Que Auschwitz não se repita: a educação contra a frieza na primeira infância. Revista Observatório, Palmas, v. 4, n. 2, p. 500-515, 2018. Disponível em: https://sistemas.uft.edu.br/periodicos/index.php/observatorio/article/view/5120/12753. Acesso em 20 jan. 2020.RODRIGUES, Tiago Nogueira Hyras e Chagas. Sobre violências e pedagogias. In: RIFIOTIS, Theophilos; RODRIGUES, Tiago Nogueira Hyras e Chagas (Org.), Educação em direitos humanos: discursos críticos e temas contemporâneos. Santa Catarina: EDUFSC, 2008.SACAVINO, Susana Beatriz. Democracia e Educação em Direitos Humanos na América Latina. Petrópolis: DPA; De Petrus, Rio de Janeiro: Editora Nova América, 2009.SACAVINO, Suzana Beatriz. Educação em direitos humanos e democracia. In: CANDAU, Vera Maria Ferrão; SACAVINO, Suzana Beatriz. Educar em Direitos Humanos: construir democracia. Rio de Janeiro: DP Editora, 2000. p. 36-48.SANTOS, Ariane Gomes dos; MONTEIRO, Claudete Ferreira de Souza. Domínios dos transtornos mentais comuns em mulheres que relatam violência por parceiro íntimo. Revista Latino-Americana de Enfermagem, Ribeirão Preto, v. 26, e3099, p. 1-12, 2018. Disponível em: http://www.revistas.usp.br/rlae/article/view/156187. Acesso em: 20 fev. 2020.SILVA, Tomaz Tadeu. Identidade e diferença: uma introdução teórica e conceitual. In: SILVA, Tomaz Tadeu; HALL, Stuart; WOODWAR, Kathryn (Org.). Identidade e diferença: a perspectiva dos estudos culturais. Petrópolis, RJ: Vozes, 2014.SOUZA, Ana Carla et al. Direitos humanos e a formação de professores que ensinam ciências. Amazônia: Revista de Educação em Ciências e Matemáticas, Belém, v. 15, n. 34, p. 225-239, 2019. Disponível em: https://periodicos.ufpa.br/index.php/revistaamazonia/article/view/7123/6046. Acesso em: 30 jun.2020.STORI, Noberto. Apresentação. In: STORI, Noberto. O despertar da sensibilidade na educação. São Paulo: Instituto Presbiteriano Mackensie; Cultura Acadêmica Editora, 2003. p.11-14.TOSI, Giuseppe. Apresentação. In: TOSI, Giuseppe (Org.). Direitos humanos: história, teoria e prática. João Pessoa: Editora UFPB, 2004. p. 5-13.TOSI, Giuseppe; FERREIRA, Lúcia de Fátima Guerra. Educação em direitos humanos nos sistemas internacional e nacional. In: FLORES, Elio Chaves; FERREIRA, Lúcia de Fátima Guerra; MELO, Vilma de Lurdes Barbosa (Org.). Educação em Direitos Humanos Educação para os Direitos Humanos. João Pessoa/PB: Editora Universitária da UFPB, 2014. p. 37-63.ZANCAN, Natália; WASSERMANN, Virginia; LIMA, Gabriela Quadros de. A violência doméstica a partir do discurso de mulheres agredidas. Pensando Famílias, Porto Alegre, v. 17, n. 1, p. 63-76, 2013. Disponível em: http://pepsic.bvsalud.org/pdf/penf/v17n1/v17n1a07.pdf. Acesso em: 20 nov. 2019.WORLD HEALTH ORGANIZATION. Global and regional estimates of violence against women: prevalence and health effects of intimate partner violence and non-partner sexual violence. Geneva: World Health Organization, 2013. Disponível em: https://apps.who.int/iris/bitstream/handle/10665/85239/9789241564625_eng.pdf;jsessionid=8BE1CA80D28EEB31E26A8E0782E91B8B?sequence=1. Acesso em: 18 nov. 2019.
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Goicoechea, Javier R., Miriam G. Santa-Maria, Emeric Bron, David Teyssier, Nuria Marcelino, José Cernicharo, and Sara Cuadrado. "Molecular tracers of radiative feedback in Orion (OMC-1)." Astronomy & Astrophysics 622 (February 2019): A91. http://dx.doi.org/10.1051/0004-6361/201834409.

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Young massive stars regulate the physical conditions, ionization, and fate of their natal molecular cloud and surroundings. It is important to find tracers that quantify the stellar feedback processes that take place on different spatial scales. We present ~85 arcmin2 velocity-resolved maps of several submillimeter molecular lines, taken with Herschel/HIFI, toward the closest high-mass star-forming region, the Orion molecular cloud 1 core (OMC-1). The observed rotational lines include probes of warm and dense molecular gas that are difficult, if not impossible, to detect from ground-based telescopes: CH+ (J = 1–0), CO (J = 10–9), HCO+ (J = 6–5), HCN (J = 6–5), and CH (N, J = 1, 3/2–1, 1/2). These lines trace an extended but thin layer (AV ≃ 3–6 mag or ~1016 cm) of molecular gas at high thermal pressure, Pth = nH ⋅ Tk ≈ 107–109 cm−3 K, associated with the far-ultraviolet (FUV) irradiated surface of OMC-1. The intense FUV radiation field – emerging from massive stars in the Trapezium cluster – heats, compresses, and photoevaporates the cloud edge. It also triggers the formation of specific reactive molecules such as CH+. We find that the CH+ (J = 1–0) emission spatially correlates with the flux of FUV photons impinging the cloud: G0 from ~103 to ~105. This relationship is supported by constant-pressure photodissociation region (PDR) models in the parameter space Pth∕G0 ≈ [5 × 103 − 8 × 104] cm−3 K where many observed PDRs seem to lie. The CH+ (J = 1–0) emission also correlates with the extended infrared emission from vibrationally excited H2 (v ≥ 1), and with that of [C II] 158 μm and CO J = 10–9, all emerging from FUV-irradiated gas. These spatial correlations link the presence of CH+ to the availability of C+ ions and of FUV-pumped H2 (v ≥ 1) molecules. We conclude that the parsec-scale CH+ emission and narrow-line (Δv ≃ 3 km s−1) mid-J CO emission arises from extended PDR gas and not from fast shocks. PDR line tracers are the smoking gun of the stellar feedback from young massive stars. The PDR cloud surface component in OMC-1, with a mass density of 120–240 M⊙ pc−2, represents ~5–10% of the total gas mass; however, it dominates the emitted line luminosity, the average CO J = 10–9 surface luminosity in the mapped region being ~35 times brighter than that of CO J = 2–1. These results provide insights into the source of submillimeter CH+ and mid-J CO emission from distant star-forming galaxies.
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Caruso, Rosario, Monica Scordino, Pasqualino Traulo, and Giacomo Gagliano. "Determination of Volatile Compounds in Wine by Gas Chromatography-Flame Ionization Detection: Comparison Between the U.S. Environmental Protection Agency 3σ Approach and Hubaux-Vos Calculation of Detection Limits Using Ordinary and Bivariate Least Squares." Journal of AOAC INTERNATIONAL 95, no. 2 (March 1, 2012): 459–71. http://dx.doi.org/10.5740/jaoacint.11-044.

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Abstract A capillary GC-flame ionization detection (FID) method to determine volatile compounds (ethyl acetate, 1,1-diethoxyethane, methyl alcohol, 1-propanol, 2-methyl-1-propanol, 2-methyl-1-butanol, 3-methyl-1-butanol, 1-butanol, and 2-butanol) in wine was investigated in terms of calculation of detection limits and calibration method. The main objectives were: (1) calculation of regression coefficient parameters by ordinary least-squares (OLS) and bivariate least-squares (BLS) regression models, taking into account errors in both axes; (2) estimation of linear dynamic range (LDR) according to International Conference on Harmonization recommendations; (3) performance evaluation of a method by using three different internal standards (ISs) such as acetonitrile, acetone, and 1-pentanol; (4) evaluation of LODs according to the U. S. Environmental Protection Agency (EPA) 3σ approach and the Hubaux-Vos (H-V) method; (5) application of H-V theory to a gas chromatographic analytical method and to a food matrix; and (6) accuracy assessment of the method relative to methyl alcohol content through a Unione Italiana Vini (UIV) interlaboratory proficiency test. Calibration curves calculated via BLS and OLS show similar slopes, while intercepts are closer to zero in the first case, independent of the chosen IS. The studied ISs show a substantially equivalent behavior, even though the IS closer to the analyte retention time seems to be more appropriate in terms of LDR and LOD. Results indicate an underestimation of LODs using the EPA 3σ approach instead of the more realistic H-V method, both with OLS and BLS regression models. Methanol contents compared with UIV average values indicate recovery between 90 and 110%.
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Wróblewski, Andrzej E. "STEREOCHEMISTRY OF 1,2-OXAPHOSPHOLANES. V. Phosphorus Shifts as a Probe of Configuration of Substituted 1,2-Oxaphospholan-3-ols." Phosphorous and Sulfur and the Related Elements 28, no. 3 (July 1986): 371–77. http://dx.doi.org/10.1080/03086648608072829.

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Asutay, Oktay, and Necdet Coskun. "ChemInform Abstract: Selective Reduction of 1,4-Diarylimidazoline-3-oxides to Imidazolidin-1-ols (II) and Hydroxylamine Derivatives (V)." ChemInform 42, no. 1 (December 9, 2010): no. http://dx.doi.org/10.1002/chin.201101103.

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Kläui, Wolfgang, Stefan Schäfer, Wilfried Peters, and Hartmut Wunderlich. "Vielseitige Koordinationschemie von Vanadium(V): Substitutionsreaktionen, Umlagerungen und Kondensationsreaktionen von Oxovanadium(V)-Komplexen des tripodalen Sauerstoffliganden LOMe− = [η5-(C5H5)Co{P(OMe)2(O)}3]−." Zeitschrift für anorganische und allgemeine Chemie 632, no. 15 (November 2006): 2447–52. http://dx.doi.org/10.1002/zaac.200600211.

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Dou, Shuai-yong, and Rui Wang. "Study on the performance and mechanism of aerobic oxidative desulfurization based on a dual-functional material possessing catalytic and adsorptive properties." New Journal of Chemistry 43, no. 7 (2019): 3226–35. http://dx.doi.org/10.1039/c8nj05896b.

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Herein, three polyoxometalates, namely K3PW12O40·10H2O, K6[α-P2W18O62]·14H2O, and K8H[P2W15V3O62]·9H2O, were successfully prepared and used in the air/n-octanaloxidative desulfurization (ODS) system.
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Baronas, Darius. "Werner Paravicini. Adlig leben im 14. Jahrhundert. Weshalb sie fuhren: Die Preußenreisen des europäischen Adels." Ordines Militares Colloquia Torunensia Historica 26 (November 9, 2021): 407–11. http://dx.doi.org/10.12775/om.2021.021.

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Werner Paravicini. Adlig leben im 14. Jahrhundert. Weshalb sie fuhren: Die Preußenreisen des europäischen Adels. Tl. 3. Vestigia Prussica 2. Göttingen: V & R unipress, 2020. 807 pp. ISBN: 978-3-8471-1128-3.
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Kläui, Wolfgang, Stefan Schäfer, and Hartmut Wunderlich. "Synthese von Oxovanadium(V)-halogeno-Komplexen der tripodalen Sauerstoffliganden LR— = [η5-(C5H5)Co{PR2(O)}3]—, R = OMe, OEt." Zeitschrift für anorganische und allgemeine Chemie 629, no. 11 (October 2003): 1907–11. http://dx.doi.org/10.1002/zaac.200300065.

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Vasquez Bone, Katterine Kariuxy, Ana Emperatriz Yupa Pallchisaca, and David Leonardo Serdan Ruiz. "Physiological alteration of the menstrual cycle caused by emotions and stress derived from social distancing." Universidad Ciencia y Tecnología 25, no. 110 (August 27, 2021): 181–90. http://dx.doi.org/10.47460/uct.v25i110.490.

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The main objective of this work was to explore whether stress or negative emotions caused by social isolation produce physiological alterations in menstruation. A study was carried out with women between 25 and 45 years of age. The bibliography reveals important findings related to menstrual disorders resulting from difficult situations that could affect women of reproductive age. A quantitative, exploratory and descriptive method was used. The results of the survey revealed that the research subjects suffered distress due to financial difficulties, as well as the danger of becoming ill or their relatives. However, there is not enough evidence that due to the social distancing product of the Covid-19 pandemic, as a cause of stressful situations and negative emotions, it has caused physiological imbalances that affect the menstrual cycle. Keywords: Stress, emotions, menstrual cycle, social isolation, menstrual disorders. References [1]OMS, Una guia de las orientaciones de la OMS, Ginebra, Suiza: Organización Mundial de la Salud. [Online] Available: https://www.who.int/es/news-room/feature-stories/detail/a-guide-to-who-s-guidance, 2020. [2]Euronews en español, «El modelo sueco contra la Covid-19 vuelve a ser envidiado en Europa,» Euronews, pp. [Online] Available: https://es.euronews.com/2020/09/09/el-modelo-sueco-contra-la-covid-19-vuelve-a-ser-envidiado-en-europa., 09 09 2020. [3]L. Barrucho, «Coronavirus: Brasil es el ejemplo de todo lo que podía salir mal en una pandemia,» BBC News Mundo, pp. [Online] Available: https://www.bbc.com/mundo/noticias-america-latina-56510603, 25 03 2021. [4]BBC News Mundo, «Coronavirus en Estados Unidos: 5 cifras que muestran cómo la pandemia de coronavirus está fuera de control en el país.,» BBC News Mundo, pp. [Online] Available: https://www.bbc.com/mundo/noticias-internacional-54912864 , 14 11 2020. [5]D. Olmo, «Coronavirus en Venezuela: qué es el sistema 7+7, la peculiar cuarentena con la que el país trata de frenar el avance de la Covid-19,» BBC News Mundo, pp. [Online] Available: https://www.bbc.com/mundo/noticias-america-latina-53187996 , 29 06 2020. [6]P. Naveira, «Toque de queda: en qué países se aplica ya la medida,» AS, p. [Online] Available: https://as.com/diarioas/2020/10/23/actualidad/1603454324_809869.html , 23 10 2020. [7]S. Boccino, «Salud mental de la Mujer: Síntomas y Trastornos Premenstruales. Clinica y tratamiento,» Revista de Psiquiaría del Uruguay., vol. 68, nº 1, pp. 78-89, 2004. [8]H. Selye, «The stress concept: past. present and future,» de Stress resarch: issues for the eighties, New York, John Wiley & Sons, 1986. [9]M. Naranjo, «Una revisión teórica sobre el estrés y algunos aspectos relevantes de éste en el ámbito educativo,» Revista Educación, vol. 33, nº 2, pp. 171-190, 2009. [10]M. Escobar, A. Pipman, G. Aracari, M. Alonso y M. Blanco, «Transtornos del ciclo menstrual en la adolescencia,» Revista Arch Argent Pediatr, vol. 108, nº 4, pp. 363-369, 2010. [11]American Psychological Association, «Los distintos tipos de estrés,» American Psychological Association, 2013. [Online] Available: http://www.apa.org/centrodeapoyo/tipos. [Last access: 5 04 2021]. [12]MSD, «Manual MSD versión para público general, terminología médica de los trastornos menstruales,» MSD, S/F. [Online] Available: https://www.msdmanuals.com/es-ve/hogar/multimedia/table/v802727_es . [Last access: 25 04 2021]. [13]F. Daneri, «Psicología del Estrés,» de Biología del Comportamiento, Buenos Aires, Universidad de Buenos Aires, 2012, pp. 1-25. [14]M. Boutot, «El estrés y el ciclo menstrual,» helloclue.com, 9 11 2016. [Online] Available: https://helloclue.com/es/articulos/emociones/el-estres-y-el-ciclo-menstrual. [Last access: 05 04 2021]. [15]C. M. Quirce, «Una teoría nueva sobre el estrés,» Avances de investigación, nº 6, pp. 1-34, 1976. [16]F. Duval, F. González y H. Rabia, «Neurobiología del estrés,» Rev. Chil. neuropsiquiatr., vol. 48, nº 4, pp. [Online] Available: http://dx.doi.org/10.4067/S0717-92272010000500006, 2010. [17]R. Calle, La psicología del sosiego en el trabajo y la empresa. ¿se puede prevenir el estrés y la ansiedad en trabajos que exigen mucha atención o dedicación?, Bogotá: Intermedio editores, 2005. [18]S. Nogareda, Fisiología del estrés, Madrid, España: Instituto nacional de seguridad e higiene en el trabajo, Ministerio del trabajo y asuntos sociales, S/F. [19]A. López-Mato, I. G. Illia, O. Boullosa, C. Márquez y A. Vieitez, «Transtorno disfórico premenstrual,» Rev. Chil. NeuroPsiquiatr., vol. 38, nº 3, pp. 187-195, 2000. [20]G. Witkin, The female stress survival guide, New York: Newmarket Press, 2000. [21]j. A. Piqueras Rodríguez, V. Ramos Linárez, A. E. Martínez González y L. A. Oblitas Guadalupe, «Emociones negativas y su impacto en la salud mental y física,» Suma Psicológica, vol. 16, nº 2, pp. 85-112, 2009. [22]L. Zanin, A. Páez, C. Correa y M. De Bortoli, «Ciclo menstrual: sintomatología y regularidad del estilo de vida diario,» Fundamentos en Humanidades, vol. XII, nº 24, pp. 103-123, 2011. [23]H. Markel, H. B. Lipman, A. Navarro, A. Sloan, J. R. Michalsen, A. M. Stern y M. Cetron, «Nonpharmaceutical Interventions Implemented by US Cities during the 1918-1919 influenza pndemic,» JAMA, vol. 298, nº 6, pp. 644-655, 2007. [24]M. Foucoult, Vigilar y castigar: el nacimiento de la prisión, Buenos Aires, Argentina: Siglo XXI editores, 2002. [25]F. Planas Padrós, «El modelo sueco contra la Covid-19,» La Vanguardia, pp. [Online] Available: https://www.lavanguardia.com/participacion/lectores-, 31 07 2020. [26]BBC Mundo, «Fracasamos: qué pasó con el polémico plan suecia contra la Covid-19 que ahora es criticado por el rey del país,» BBC News, pp. [Online] Available: https://www.bbc.com/mundo/noticias-internacional-55354591, 17 12 2020. [27]Alerta Legal, «Modelo de flexibilización 7x7 y sectores autorizados para laborar,» Torres Plas & Araujo abogados, pp. [Online] Available: https://torresplazaraujo.com/actualidad/alerta-legal-modelo-de-flexibilizaci%C3%B3n-7x7-y-sectores-autorizados-para-laboral, 10 06 2020. [28]R. Marquina Medina y L. Jaramillo-Valverde, «Cuarentena y su impacto psicológico en la población,» 12 2020. [Online] Available. Disponible en: file:///C:/Users/Thinkpad/Downloads/452-Preprint%20Text-567-2-10-20200512.pdf. [Last access: 05 05 2021].
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47

Zhu, Lei, Xinyue Li, Xixi Hu, Xin Wu, Yunqing Liu, Yiming Yang, Yanqing Zang, Huacheng Tang, Changyuan Wang, and Jingyu Xu. "Quality Characteristics and Anthocyanin Profiles of Different Vitis amurensis Grape Cultivars and Hybrids from Chinese Germplasm." Molecules 26, no. 21 (November 5, 2021): 6696. http://dx.doi.org/10.3390/molecules26216696.

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To evaluate the important Vitis amurensis germplasm, the quality characteristics and anthocyanin profiles of the ripe berries of 20 V. amurensis grapes and 11 interspecific hybrids in two consecutive years were analysed. Compared with the V. vinifera grapes, V. amurensis grapes had small berries with low total soluble solids and high titratable acids, and were richer in phenolic compounds except for flanan-3-ols in their skins but had lower phenolic contents in their seeds and showed lower antioxidant activities. An outstanding feature of the V. amurensis grapes was their abundant anthocyanin contents, which was 8.18-fold higher than the three wine grapes of V. vinifera. The anthocyanin composition of V. amurensis was characterized by an extremely high proportion of diglucoside anthocyanins (91.71%) and low acylated anthocyanins (0.04%). Interestingly, a new type of speculated 3,5,7-O-triglucoside anthocyanins was first identified and only detected in V. amurensis grapes and hybrids. Based on the total phenolic and anthocyanin characteristics, V. amurensis grapes were set apart from V. vinifera cultivars and the interspecific hybrids, for the same qualities, fell between them, as assessed by principal component analysis.
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48

Banerjee, Sambaran. "Stellar-mass black holes in young massive and open stellar clusters – V. comparisons with LIGO-Virgo merger rate densities." Monthly Notices of the Royal Astronomical Society 503, no. 3 (March 2, 2021): 3371–85. http://dx.doi.org/10.1093/mnras/stab591.

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ABSTRACT I study the contribution of young massive star clusters (YMCs) and open star clusters (OCs) to the present day, intrinsic merger rate density of dynamically assembled binary black holes (BBHs). The BBH merger event rate is estimated based on a set of state-of-the-art evolutionary models of star clusters, as presented in Banerjee (2021). The merger-event rates are obtained by constructing a cluster population of the Universe, out of the models, taking into account mass distribution of clusters and cosmic star formation and enrichment histories, as per observations. The model BBH merger rate density ranges from a pessimistic to a reference value of 0.5−37.9 yr−1 Gpc−3, for a LIGO-Virgo-like detector horizon. The reference rate well accommodates the BBH merger rate densities estimated from GWTC-1 and GWTC-2 merger-event catalogues. The computed models also yield differential BBH merger rate densities that agree reasonably with those from GWTC-1 and, as well, with the much more constrained ones from GWTC-2. These results suggest that dynamical interactions in YMCs and OCs can, in principle, alone explain the BBH merger rate density and its dependence on the merging-binary properties, as inferred from to-date gravitational-wave (GW) events. The cosmic merger rate density evolution also agrees with GWTC-2. The models predict a rate of ≈5 yr−1 Gpc−3 for eccentric LIGO-Virgo mergers from YMCs and OCs. The improving constraints on BBH merger rate density with mounting GW events will help constraining scenarios of star cluster formation across cosmic time and as well the relative contributions of the various compact binary merger channels.
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49

Horii, Shozo, Chie Momma, Kayoko Miyahara, Tsutomu Maruyama, and Masao Matsumoto. "Liquid Chromatographic Determination Of Three Sulfonamides In Animal Tissue And Egg." Journal of AOAC INTERNATIONAL 73, no. 6 (November 1, 1990): 990–92. http://dx.doi.org/10.1093/jaoac/73.6.990.

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Abstract Sulfonamides are widely used as a feed additive in animal production In Japan. The present paper is a determination of 3 sulfonamides: sulfamethazine (SMZ), sulfamonomethoxlne [SMX, 4-amino-/V-(3-methoxypyrazlnyl)-benzenesulfonamlde], and suifadimethoxine (SDX) in animal tissue and egg by liquid chromatography (LC). Tissues were extracted with acetonltrlle and fat was removed by liquid/liquid partition. The sulfonamides were purified by an ODS cartridge column; then each compound was separated by an ODS LC column and detected at 268 nm. Quantification levels were 0.02 ppm for SMZ and SMX, and 0.04 ppm for SDX; detection limits were 0.01 ppm for SMZ and SMX, and 0.02 ppm for SDX. Calibration curves were linear between 2 and 40 ng for SMZ and SMX, and between 4 and 80 ng for SDX. Recoveries from muscle and egg samples spiked with 1-2 /μg/10 g were 8 1 - 98%.
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50

Lin, D., B. Gooden, M. Lyons, L. Salmon, K. Martina, K. Sundaraj, J. Yong Yau Tai, and M. O'Sullivan. "THE DEGREE OF GLUTEAL TENDINOPATHY CORRELATES WITH WORSENING PROMS IN TOTAL HIP ARTHROPLASTY: A PROSPECTIVE STUDY OF 797 PATIENTS." Orthopaedic Proceedings 105-B, SUPP_2 (February 2023): 115. http://dx.doi.org/10.1302/1358-992x.2023.2.115.

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Abstract:
The prevalence of gluteal tendinopathy (GT) associated with osteoarthritis of the hip is difficult to determine as it is frequently undiagnosed or misdiagnosed as trochanteric bursitis. Its relationship to total hip arthroplasty (THA) outcomes is currently unknown. The aim of this study was to determine the incidence of GT at the time of hip arthroplasty and examine the relationship between GT and patient reported outcomes (PROMS) before and after THA.Patients undergoing THA for primary osteoarthritis between August 2017 and August 2020 were recruited. Tendinopathy was assessed and graded at time of surgery. PROMS included the Oxford Hip Score (OHS), HOOS JR, EQ-5D, and were collected preoperatively and at one year after THA. Satisfaction with surgery was also assessed at 1 year.797 patients met eligibility criteria and were graded as Grade 1: normal tendons (n =496, 62%), Grade 2: gluteal tendinopathy but no tear (n=222, 28%), Grade 3: partial/full thickness tears or bare trochanter (n=79, 10%). Patients with abnormal gluteal tendons were older (p=0.001), had a higher mean BMI (p=0.01), and were predominately female (p=0.001). Patients with higher grade tendinopathy had statistically significant inferior PROMS at one year, OHS score (44.1 v 42.9 v 41.3, p 0.001) HOOS JR (89.3 V 86.3 V 85.6 p 0.005). Increasing gluteal tendon grade was associated with a greater incidence of problems with mobility (p=0.001), usual activities (p=0.001) and pain (p=0.021) on EQ5D. There was a 3 times relative risk of overall dissatisfaction with THA in the presence of gluteal tears.This study demonstrated that gluteal tendinopathy was commonly observed and associated with inferior 1-year PROMS in patients undergoing THA for OA. Increasing degree of tendinopathy was a negative prognostic factor for worse functional outcomes and patient satisfaction.
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