Journal articles on the topic 'Oligonucleotidi antisenso'
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Goddard, Layla R., Charlotte E. Mardle, Hassan Gneid, Ciara G. Ball, Darren M. Gowers, Helen S. Atkins, Louise E. Butt, Jonathan K. Watts, Helen A. Vincent, and Anastasia J. Callaghan. "An Investigation into the Potential of Targeting Escherichia coli rne mRNA with Locked Nucleic Acid (LNA) Gapmers as an Antibacterial Strategy." Molecules 26, no. 11 (June 4, 2021): 3414. http://dx.doi.org/10.3390/molecules26113414.
Full textBožič, Tim, Matja Zalar, Boris Rogelj, Janez Plavec, and Primož Šket. "Structural Diversity of Sense and Antisense RNA Hexanucleotide Repeats Associated with ALS and FTLD." Molecules 25, no. 3 (January 25, 2020): 525. http://dx.doi.org/10.3390/molecules25030525.
Full textDung, Tran Huu, Seung-Rok Lee, Suhk-Dong Han, Seon-Jeong Kim, Yeon-Mi Ju, Myong-Soo Kim, and Hoon Yoo. "Chitosan-TPP Nanoparticle as a Release System of Antisense Oligonucleotide in the Oral Environment." Journal of Nanoscience and Nanotechnology 7, no. 11 (November 1, 2007): 3695–99. http://dx.doi.org/10.1166/jnn.2007.041.
Full textCHAKRABORTY, Rila, Dalia DASGUPTA, Samit ADHYA, and Mukul K. BASU. "Cationic liposome-encapsulated antisense oligonucleotide mediates efficient killing of intracellular Leishmania." Biochemical Journal 340, no. 2 (May 25, 1999): 393–96. http://dx.doi.org/10.1042/bj3400393.
Full textZhao, Q., X. Song, T. Waldschmidt, E. Fisher, and AM Krieg. "Oligonucleotide uptake in human hematopoietic cells is increased in leukemia and is related to cellular activation." Blood 88, no. 5 (September 1, 1996): 1788–95. http://dx.doi.org/10.1182/blood.v88.5.1788.1788.
Full textZhao, Q., X. Song, T. Waldschmidt, E. Fisher, and AM Krieg. "Oligonucleotide uptake in human hematopoietic cells is increased in leukemia and is related to cellular activation." Blood 88, no. 5 (September 1, 1996): 1788–95. http://dx.doi.org/10.1182/blood.v88.5.1788.bloodjournal8851788.
Full textStudzińska, Sylwia, Ewelina Zawadzka, Szymon Bocian, and Michał Szumski. "Synthesis and application of stationary phase for DNA-affinity chromatographic analysis of unmodified and antisense oligonucleotide." Analytical and Bioanalytical Chemistry 413, no. 20 (June 24, 2021): 5109–19. http://dx.doi.org/10.1007/s00216-021-03473-7.
Full textPandiri, Kavya, Mohammed Abdul Samad, Nadeem Abbas Gulamus, and Hajera Khanam. "Medicinal Applications of Antisense Oligonucleotides: A Review." INTERNATIONAL JOURNAL OF APPLIED PHARMACEUTICAL SCIENCES AND RESEARCH 5, no. 02 (April 1, 2020): 30–36. http://dx.doi.org/10.21477/ijapsr.5.2.2.
Full textYamamoto, T., R. P. Moerschell, L. P. Wakem, S. Komar-Panicucci, and F. Sherman. "Strand-specificity in the transformation of yeast with synthetic oligonucleotides." Genetics 131, no. 4 (August 1, 1992): 811–19. http://dx.doi.org/10.1093/genetics/131.4.811.
Full textTanaka, T., C. C. Chu, and W. E. Paul. "An antisense oligonucleotide complementary to a sequence in I gamma 2b increases gamma 2b germline transcripts, stimulates B cell DNA synthesis, and inhibits immunoglobulin secretion." Journal of Experimental Medicine 175, no. 2 (February 1, 1992): 597–607. http://dx.doi.org/10.1084/jem.175.2.597.
Full textLeung-Hagesteijn, C. Y., K. Milankov, M. Michalak, J. Wilkins, and S. Dedhar. "Cell attachment to extracellular matrix substrates is inhibited upon downregulation of expression of calreticulin, an intracellular integrin alpha-subunit-binding protein." Journal of Cell Science 107, no. 3 (March 1, 1994): 589–600. http://dx.doi.org/10.1242/jcs.107.3.589.
Full textBennett, C. F., T. P. Condon, S. Grimm, H. Chan, and M. Y. Chiang. "Inhibition of endothelial cell adhesion molecule expression with antisense oligonucleotides." Journal of Immunology 152, no. 7 (April 1, 1994): 3530–40. http://dx.doi.org/10.4049/jimmunol.152.7.3530.
Full textAoki, Yoshitsugu, Tetsuya Nagata, and Shin’ichi Takeda. "New Approach for Antisense Oligonucleotide-Mediated Exon Skipping in Duchenne Muscular Dystrophy." Journal of Advanced Computational Intelligence and Intelligent Informatics 16, no. 4 (June 20, 2012): 521–26. http://dx.doi.org/10.20965/jaciii.2012.p0521.
Full textJuliano, Rudolph L. "Chemical Manipulation of the Endosome Trafficking Machinery: Implications for Oligonucleotide Delivery." Biomedicines 9, no. 5 (May 5, 2021): 512. http://dx.doi.org/10.3390/biomedicines9050512.
Full textZhang, R., Z. Lu, X. Zhang, H. Zhao, R. B. Diasio, T. Liu, Z. Jiang, and S. Agrawal. "In vivo stability and disposition of a self-stabilized oligodeoxynucleotide phosphorothioate in rats." Clinical Chemistry 41, no. 6 (June 1, 1995): 836–43. http://dx.doi.org/10.1093/clinchem/41.6.836.
Full textLesnikowski, Zbigniew J., Marzena Przepiórkiewicz, Yutaka Tamura, Hideko Kaji, and Eric Wickstrom. "P-Chiral Oligonucleotides. Effect of Configuration at Phosphorus on Transport of Tetra(thymidine Methylphosphonate)s Across Organic Liquid Membrane." Collection of Czechoslovak Chemical Communications 66, no. 6 (2001): 912–22. http://dx.doi.org/10.1135/cccc20010912.
Full textEpple, Sven, Cameron Thorpe, Ysobel R. Baker, Afaf H. El-Sagheer, and Tom Brown. "Consecutive 5′- and 3′-amide linkages stabilise antisense oligonucleotides and elicit an efficient RNase H response." Chemical Communications 56, no. 41 (2020): 5496–99. http://dx.doi.org/10.1039/d0cc00444h.
Full textYuan, Ahu, Yiqiao Hu, and Xin Ming. "Dendrimer conjugates for light-activated delivery of antisense oligonucleotides." RSC Advances 5, no. 44 (2015): 35195–200. http://dx.doi.org/10.1039/c5ra04091d.
Full textHowell, B., H. Deacon, and L. Cassimeris. "Decreasing oncoprotein 18/stathmin levels reduces microtubule catastrophes and increases microtubule polymer in vivo." Journal of Cell Science 112, no. 21 (November 1, 1999): 3713–22. http://dx.doi.org/10.1242/jcs.112.21.3713.
Full textSIPES, TAMARA B., and SUSAN M. FREIER. "PREDICTION OF ANTISENSE OLIGONUCLEOTIDE EFFICACY USING AGGREGATE MOTIFS." Journal of Bioinformatics and Computational Biology 06, no. 05 (October 2008): 919–32. http://dx.doi.org/10.1142/s0219720008003795.
Full textHe, Xiao-Yang, Jing Wang, Dan-Dan Lu, and Sheng-Qi Wang. "Synthesis and Antisense Properties of 2′β-F-Arabinouridine Modified Oligonucleotides with 4′-C-OMe Substituent." Molecules 23, no. 9 (September 17, 2018): 2374. http://dx.doi.org/10.3390/molecules23092374.
Full textOberemok, Volodymyr V., Oksana A. Andreeva, and Edie E. Alieva. "DNA Oligonucleotides as Antivirals and Vaccine Constituents against SARS Coronaviruses: A Prospective Tool for Immune System Tuning." International Journal of Molecular Sciences 24, no. 2 (January 13, 2023): 1553. http://dx.doi.org/10.3390/ijms24021553.
Full textPatutina, Olga A., Svetlana K. Gaponova (Miroshnichenko), Aleksandra V. Sen’kova, Innokenty A. Savin, Daniil V. Gladkikh, Ekaterine A. Burakova, Alesya A. Fokina, et al. "Mesyl phosphoramidate backbone modified antisense oligonucleotides targeting miR-21 with enhanced in vivo therapeutic potency." Proceedings of the National Academy of Sciences 117, no. 51 (December 7, 2020): 32370–79. http://dx.doi.org/10.1073/pnas.2016158117.
Full textNair, S. K., D. Snyder, and E. Gilboa. "Cells treated with TAP-2 antisense oligonucleotides are potent antigen-presenting cells in vitro and in vivo." Journal of Immunology 156, no. 5 (March 1, 1996): 1772–80. http://dx.doi.org/10.4049/jimmunol.156.5.1772.
Full textSHARPE, CLAIRE C., MARK E. C. DOCKRELL, MAZHAR I. NOOR, BRETT P. MONIA, and BRUCE M. HENDRY. "Role of Ras Isoforms in the Stimulated Proliferation of Human Renal Fibroblasts in Primary Culture." Journal of the American Society of Nephrology 11, no. 9 (September 2000): 1600–1606. http://dx.doi.org/10.1681/asn.v1191600.
Full textWhite, D. G., K. Maneewannakul, E. von Hofe, M. Zillman, W. Eisenberg, A. K. Field, and S. B. Levy. "Inhibition of the multiple antibiotic resistance (mar) operon in Escherichia coli by antisense DNA analogs." Antimicrobial Agents and Chemotherapy 41, no. 12 (December 1997): 2699–704. http://dx.doi.org/10.1128/aac.41.12.2699.
Full textAllinquant, B., P. Hantraye, P. Mailleux, K. Moya, C. Bouillot, and A. Prochiantz. "Downregulation of amyloid precursor protein inhibits neurite outgrowth in vitro." Journal of Cell Biology 128, no. 5 (March 1, 1995): 919–27. http://dx.doi.org/10.1083/jcb.128.5.919.
Full textWatts, Jonathan K., and Masad J. Damha. "2′F-Arabinonucleic acids (2′F-ANA) — History, properties, and new frontiers." Canadian Journal of Chemistry 86, no. 7 (July 1, 2008): 641–56. http://dx.doi.org/10.1139/v08-049.
Full textSheffield, LG. "Epidermal growth factor as an autocrine modulator of stress response in mammary epithelial cells." Journal of Endocrinology 159, no. 1 (October 1, 1998): 111–16. http://dx.doi.org/10.1677/joe.0.1590111.
Full textYu, Chien-Hung, Mathieu H. M. Noteborn, and René C. L. Olsthoorn. "Stimulation of ribosomal frameshifting by antisense LNA." Nucleic Acids Research 38, no. 22 (August 6, 2010): 8277–83. http://dx.doi.org/10.1093/nar/gkq650.
Full textKobylańska, A., E. Pluskota, M. Swiatkowska, M. Wójcik, A. Cierniewska-Cieślak, A. Krakowiak, M. Boczkowska, et al. "Inhibition of plasminogen activator inhibitor release in endothelial cell cultures by antisense oligodeoxyribonucleotides with a 5'-end lipophilic modification." Acta Biochimica Polonica 46, no. 3 (September 30, 1999): 679–91. http://dx.doi.org/10.18388/abp.1999_4140.
Full textPitout, Ianthe, Loren L. Flynn, Steve D. Wilton, and Sue Fletcher. "Antisense-mediated splice intervention to treat human disease: the odyssey continues." F1000Research 8 (May 22, 2019): 710. http://dx.doi.org/10.12688/f1000research.18466.1.
Full textFrankel, Bruce, Sharon L. Longo, Gerard S. Rodziewicz, and Charles J. Hodge. "Antisense oligonucleotide—induced inhibition of adrenocorticotropic hormone release from cultured human corticotrophs." Journal of Neurosurgery 91, no. 2 (August 1999): 261–67. http://dx.doi.org/10.3171/jns.1999.91.2.0261.
Full textDuval, Carine, Anne Nègre-Salvayre, Alain Doglio, Robert Salvayre, Luc Pénicaud, and Louis Casteilla. "Increased reactive oxygen species production with antisense oligonucleotides directed against uncoupling protein 2 in murine endothelial cells." Biochemistry and Cell Biology 80, no. 6 (December 1, 2002): 757–64. http://dx.doi.org/10.1139/o02-158.
Full textMisiura, K., M. Wójcik, A. Krakowiak, M. Koziołkiewicz, Z. Pawłowska, E. Pluskota, C. S. Cierniewski, and W. J. Stec. "Synthesis, biochemical and biological studies on oligonucleotides bearing a lipophilic dimethoxytrityl group." Acta Biochimica Polonica 45, no. 1 (March 31, 1998): 27–32. http://dx.doi.org/10.18388/abp.1998_4315.
Full textOzvaran, Mustafa K., Xiaobo X. Cao, Steven D. Miller, Brett A. Monia, Waun Ki Hong, and W. Roy Smythe. "Antisense oligonucleotides directed at the bcl-xl gene product augment chemotherapy response in mesothelioma." Molecular Cancer Therapeutics 3, no. 5 (May 1, 2004): 545–50. http://dx.doi.org/10.1158/1535-7163.545.3.5.
Full textJeromin, A., R. L. Huganir, and D. J. Linden. "Suppression of the glutamate receptor delta 2 subunit produces a specific impairment in cerebellar long-term depression." Journal of Neurophysiology 76, no. 5 (November 1, 1996): 3578–83. http://dx.doi.org/10.1152/jn.1996.76.5.3578.
Full textAbe, T., S. Suzuki, T. Hatta, K. Takai, T. Yokota, and H. Takaku. "Specific Inhibition of Influenza Virus RNA Polymerase and Nucleoprotein Gene Expression by Liposomally Encapsulated Antisense Phosphorothioate Oligonucleotides in MDCK Cells." Antiviral Chemistry and Chemotherapy 9, no. 3 (June 1998): 253–62. http://dx.doi.org/10.1177/095632029800900306.
Full textZhao, Q., T. Waldschmidt, E. Fisher, CJ Herrera, and AM Krieg. "Stage-specific oligonucleotide uptake in murine bone marrow B-cell precursors." Blood 84, no. 11 (December 1, 1994): 3660–66. http://dx.doi.org/10.1182/blood.v84.11.3660.bloodjournal84113660.
Full textSusol, N. U. "INHIBITION OF THE EXPRESSION OF PHYSIOLOGICAL PRIONS WITH ANTISENS-OLIGONUCLEOTIDES." Biotechnologia Acta 10, no. 5 (October 2017): 43–50. http://dx.doi.org/10.15407/biotech10.05.043.
Full textSanghvi, Yogesh S., V. T. Ravikumar, Anthony N. Scozzari, and Douglas L. Cole. "Applications of green chemistry in the manufacture of oligonucleotide drugs." Pure and Applied Chemistry 73, no. 1 (January 1, 2001): 175–80. http://dx.doi.org/10.1351/pac200173010175.
Full textBalcerzak, D., S. Poussard, J. J. Brustis, N. Elamrani, M. Soriano, P. Cottin, and A. Ducastaing. "An antisense oligodeoxyribonucleotide to m-calpain mRNA inhibits myoblast fusion." Journal of Cell Science 108, no. 5 (May 1, 1995): 2077–82. http://dx.doi.org/10.1242/jcs.108.5.2077.
Full textYamamoto, Tsuyoshi, Hidenori Yasuhara, Fumito Wada, Mariko Harada-Shiba, Takeshi Imanishi, and Satoshi Obika. "Superior Silencing by 2′,4′-BNANC-Based Short Antisense Oligonucleotides Compared to 2′,4′-BNA/LNA-Based Apolipoprotein B Antisense Inhibitors." Journal of Nucleic Acids 2012 (2012): 1–7. http://dx.doi.org/10.1155/2012/707323.
Full textAgramunt, Jordi, Enrique Pedroso, Silvia Kreda, Rudolph Juliano, and Anna Grandas. "Retro-1-Oligonucleotide Conjugates. Synthesis and Biological Evaluation." Molecules 24, no. 3 (February 6, 2019): 579. http://dx.doi.org/10.3390/molecules24030579.
Full textYuan, Ahu, Brian Laing, Yiqiao Hu, and Xin Ming. "Direct oligonucleotide–photosensitizer conjugates for photochemical delivery of antisense oligonucleotides." Chemical Communications 51, no. 30 (2015): 6678–80. http://dx.doi.org/10.1039/c5cc00573f.
Full textLi, Yanjie, Jixue Li, Jun Wang, David R. Lynch, Xiulong Shen, David R. Corey, Darshan Parekh, et al. "Targeting 3′ and 5′ untranslated regions with antisense oligonucleotides to stabilize frataxin mRNA and increase protein expression." Nucleic Acids Research 49, no. 20 (October 28, 2021): 11560–74. http://dx.doi.org/10.1093/nar/gkab954.
Full textTakakura, Kazuki, Atsushi Kawamura, Yuichi Torisu, Shigeo Koido, Naohisa Yahagi, and Masayuki Saruta. "The Clinical Potential of Oligonucleotide Therapeutics against Pancreatic Cancer." International Journal of Molecular Sciences 20, no. 13 (July 6, 2019): 3331. http://dx.doi.org/10.3390/ijms20133331.
Full textVictorio, Carla Bianca Luena, Wisna Novera, Jing Yang Tham, Satoru Watanabe, Subhash G. Vasudevan, and Ann-Marie Chacko. "Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers for In Situ Live-Cell Molecular Imaging of Dengue Virus Replication." International Journal of Molecular Sciences 21, no. 23 (December 4, 2020): 9260. http://dx.doi.org/10.3390/ijms21239260.
Full textMarkov, Oleg V., Anton V. Filatov, Maxim S. Kupryushkin, Ivan V. Chernikov, Olga A. Patutina, Anton A. Strunov, Elena L. Chernolovskaya, Valentin V. Vlassov, Dmitrii V. Pyshnyi, and Marina A. Zenkova. "Transport Oligonucleotides—A Novel System for Intracellular Delivery of Antisense Therapeutics." Molecules 25, no. 16 (August 11, 2020): 3663. http://dx.doi.org/10.3390/molecules25163663.
Full textKilanowska, Anna, Łukasz Nuckowski, and Sylwia Studzińska. "Studying in vitro metabolism of the first and second generation of antisense oligonucleotides with the use of ultra-high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry." Analytical and Bioanalytical Chemistry 412, no. 27 (August 27, 2020): 7453–67. http://dx.doi.org/10.1007/s00216-020-02878-0.
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