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Journal articles on the topic 'Obsessive-compulsive disorder'

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Author: Grafiati

Published: 4 June 2021

Last updated: 29 July 2024

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1

Durdle, Heather, Kevin M. Gorey, and Sherry H. Stewart. "A Meta-Analysis Examining the Relations among Pathological Gambling, Obsessive-Compulsive Disorder, and Obsessive-Compulsive Traits." Psychological Reports 103, no. 2 (October 2008): 485–98. http://dx.doi.org/10.2466/pr0.103.2.485-498.

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Pathological gambling has been proposed to belong to the obsessive-compulsive spectrum of disorders. Disorders on this spectrum are thought to share similar clinical features, neurobiology, and responses to treatment as Obsessive-Compulsive Disorder. A total of 18 studies were included in a meta-analysis to assess the strength of the association between these disorders. A strong relationship (effect size = 1. 01) was found between pathological gambling and obsessive-compulsive traits. A weak relationship was found between pathological gambling and Obsessive-Compulsive Disorder (.07) and Obsessive-Compulsive Personality Disorder (effect size = .23). These results suggest pathological gambling and Obsessive-Compulsive Disorder are distinct disorders. However, pathological gamblers do appear to show high rates of obsessive-compulsive traits relative to controls. These findings are only moderately supportive of the inclusion of pathological gambling within the obsessive-compulsive spectrum of conditions.

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2

GOODWIN, R., J. D. LIPSITZ, T. F. CHAPMAN, S. MANNUZZA, and A. J. FYER. "Obsessive–compulsive disorder and separation anxiety co-morbidity in early onset panic disorder." Psychological Medicine 31, no. 7 (October 2001): 1307–10. http://dx.doi.org/10.1017/s0033291701004366.

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Background. This study was undertaken to examine the relationship between anxiety co-morbidity and age of onset of panic disorder.Methods. Age of onset of panic disorder and co-morbid anxiety disorders were assessed among 201 panic disorder probands with childhood separation anxiety disorder, obsessive–compulsive disorder, obsessive–compulsive symptoms, social phobia and specific phobia as part of a clinician-administered lifetime diagnostic interview. A generalized linear model was used to test the association between each anxiety co-morbidity and age of panic disorder onset while simultaneously controlling for the potential confounding effects of sociodemographic characteristics and other psychiatric co-morbidity.Results. Earlier onset of panic disorder was found in patients with co-morbid obsessive–compulsive disorder, obsessive–compulsive symptoms and separation anxiety disorder, but not simple phobia or social phobia. Patients with both childhood separation anxiety disorder and obsessive–compulsive disorder had an even earlier panic onset than those with either childhood separation anxiety disorder or obsessive–compulsive disorder.Conclusions. The association between anxiety co-morbidity and earlier onset of panic disorder is specific to obsessive–compulsive disorder and childhood separation anxiety disorder.

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3

Schiele, Miriam A., Christiane Thiel, Jürgen Deckert, Michael Zaudig, Götz Berberich, and Katharina Domschke. "Monoamine Oxidase A Hypomethylation in Obsessive-Compulsive Disorder: Reversibility By Successful Psychotherapy?" International Journal of Neuropsychopharmacology 23, no. 5 (March 5, 2020): 319–23. http://dx.doi.org/10.1093/ijnp/pyaa016.

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Abstract Background Epigenetic markers such as DNA methylation of the monoamine oxidase A (MAOA) gene have previously been shown to be altered in anxiety- and stress-related disorders and to constitute a potential mechanism of action of psychotherapeutic interventions such as cognitive behavioral therapy in these disorders. The present study for the first time, to our knowledge, investigated MAOA methylation in patients with obsessive-compulsive disorder applying a longitudinal psychotherapy-epigenetic approach. Methods The present sample comprised 14 unmedicated female patients with primary obsessive-compulsive disorder and 14 age- and sex-matched healthy controls. MAOA promoter methylation was analyzed via direct sequencing of sodium bisulfite-treated DNA extracted from whole blood before and after an 8- to 10-week semi-standardized, obsessive-compulsive disorder–specific cognitive behavioral therapy. Clinical response was assessed by means of the Yale-Brown Obsessive Compulsive Scale. Results Significantly lower MAOA promoter methylation was discerned in obsessive-compulsive disorder patients relative to healthy controls. Data were available for 12 patients with obsessive-compulsive disorder and 14 controls. Furthermore, following cognitive behavioral therapy, clinical improvement, i.e., decreases in obsessive-compulsive disorder symptoms as indicated by lower scores on the Yale-Brown Obsessive Compulsive Scale was found to be significantly correlated with increases in MAOA methylation levels in patients (data available for n = 7). Conclusions The present pilot data suggest MAOA hypomethylation as a potential risk marker of obsessive-compulsive disorder and an increase in MAOA methylation levels as a possible mechanistic correlate of response to cognitive behavioral therapy in obsessive-compulsive disorder.

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4

Tavares, Hermano, and Valentim Gentil. "Pathological gambling and obsessive-compulsive disorder: towards a spectrum of disorders of volition." Revista Brasileira de Psiquiatria 29, no. 2 (June 2007): 107–17. http://dx.doi.org/10.1590/s1516-44462007000200005.

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OBJECTIVE: Pathological gambling is proposed as a participant of an impulsive-compulsive spectrum related to obsessive-compulsive disorder. This study aims to contrast pathological gambling and obsessive-compulsive disorder regarding course, comorbidity, and personality, hence testing the validity of the impulsive-compulsive spectrum. METHOD: 40 pathological gambling and 40 obsessive-compulsive disorder subjects matched to 40 healthy volunteers according to gender, age, and education were assessed with the Temperament Personality Questionnaire and the Barratt Impulsiveness Scale. Psychiatric patients were also assessed for course and comorbidity data. RESULTS: Obsessive-compulsive disorder presented an earlier onset, but the full syndrome took longer to evolve. Pathological gambling had higher comorbidity with substance-related disorders, and obsessive-compulsive disorder higher comorbidity with somatoform disorders. Gamblers scored higher than controls on the sub-factors Impulsiveness, Extravagance, Disorderliness, and Fear of Uncertainty. Obsessive-compulsive patients scored higher than controls on Fear of Uncertai-nty. Impulsiveness, Extravagance, and Disorderliness significantly correlated with the Barratt Impulsiveness Scale total score, Fear of Uncertainty did not. DISCUSSION: The course and comorbidity profiles of pathological gambling resemble an addiction and differ from obsessive-compulsive disorder. Pathological gambling combines impulsive and compulsive traits. Impulsivity and compulsivity should be regarded as orthogonal constructs, and as drives implicated in volition aspects of behavioral syndromes.

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5

Fineberg, Naomi A., Punita Sharma, Thanusha Sivakumaran, Barbara Sahakian, and Sam Chamberlain. "Does Obsessive-Compulsive Personality Disorder Belong Within the Obsessive-Compulsive Spectrum?" CNS Spectrums 12, no. 6 (June 2007): 467–82. http://dx.doi.org/10.1017/s1092852900015340.

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ABSTRACTIt has been proposed that certainDiagnostic and Statistical Manual of Mental Disorders, Fourth EditionAxis I disorders share overlapping clinical features, genetic contributions, and treatment response and fall within an “obsessive-compulsive” spectrum. Obsessive-compulsive personality disorder (OCPD) resembles obsessive-compulsive disorder (OCD) and other spectrum disorders in terms of phenomenology, comorbidity, neurocognition, and treatment response.This article critically examines the nosological profile of OCPD with special reference to OCD and related disorders. By viewing OCPD as a candidate member of the obsessive-compulsive spectrum, we gain a fresh approach to understanding its neurobiology, etiology, and potential treatments.

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6

Washington, Christi S., Peter J. Norton, and Samuel Temple. "Obsessive-Compulsive Symptoms and Obsessive-Compulsive Disorder." Journal of Nervous and Mental Disease 196, no. 6 (June 2008): 456–61. http://dx.doi.org/10.1097/nmd.0b013e3181775a62.

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7

Siddiqui, Mohammad Aleem, Daya Ram, Sanjay Kumar Munda, Shazia Veqar Siddiqui, and Sujit Sarkhel. "Prevalence of Obsessive-Compulsive Spectrum Disorders in Obsessive-Compulsive Disorder." Indian Journal of Psychological Medicine 40, no. 3 (May 2018): 225–31. http://dx.doi.org/10.4103/ijpsym.ijpsym_556_17.

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8

Denys, Damiaan. "Pharmacotherapy of Obsessive-compulsive Disorder and Obsessive-Compulsive Spectrum Disorders." Psychiatric Clinics of North America 29, no. 2 (June 2006): 553–84. http://dx.doi.org/10.1016/j.psc.2006.02.013.

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9

Lochner, C., and D. J. Stein. "Gender in obsessive-compulsive disorder and obsessive-compulsive spectrum disorders." Archives of Women's Mental Health 4, no. 1 (November 1, 2001): 19–26. http://dx.doi.org/10.1007/s007370170004.

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10

Hollander, E. "Obsessive-compulsive disorder related disorders." International Clinical Psychopharmacology 11 (December 1996): 75–88. http://dx.doi.org/10.1097/00004850-199612005-00007.

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11

Stein, D. J. "Obsessive compulsive disorder." South African Journal of Psychiatry 19, no. 3 (August 30, 2013): 7. http://dx.doi.org/10.4102/sajpsychiatry.v19i3.951.

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This guideline focuses on the pharmacotherapy of obsessive compulsive disorder(OCD). OCD is characterised by obsessions and<div style="left: 70.8662px; top: 364.72px; font-size: 15.45px; font-family: serif; transform: scaleX(0.99966);" data-canvas-width="420.56549999999993">compulsions. A number of other disorders are also characterised by</div><div style="left: 70.8662px; top: 384.72px; font-size: 15.45px; font-family: serif; transform: scaleX(0.97309);" data-canvas-width="419.07749999999993">repetitive thoughts and rituals and may also respond to modifications</div>of standard OCD treatment.

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12

Al-Sabaie, Abdullah S., Fathelaleem Abdul-Rahim, and Abdul-Razzak Al-Hamad. "Obsessive Compulsive Disorder." Annals of Saudi Medicine 12, no. 6 (November 1992): 558–61. http://dx.doi.org/10.5144/0256-4947.1992.558.

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13

Khouzam, Hani Raoul. "Obsessive-compulsive disorder." Postgraduate Medicine 106, no. 7 (January 1999): 133–41. http://dx.doi.org/10.3810/pgm.1999.12.807.

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14

Dysken, Maurice W., and John Davis. "Obsessive Compulsive Disorder." Psychiatric Annals 19, no. 2 (February 1, 1989): 63–64. http://dx.doi.org/10.3928/0048-5713-19890201-05.

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15

Kim, Chang Yoon. "Obsessive-Compulsive Disorder." Journal of the Korean Medical Association 45, no. 9 (2002): 1129. http://dx.doi.org/10.5124/jkma.2002.45.9.1129.

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16

Park, Lawrence T., James W. Jefferson, and John H. Greist. "Obsessive-Compulsive Disorder." CNS Drugs 7, no. 3 (March 1997): 187–202. http://dx.doi.org/10.2165/00023210-199707030-00003.

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17

Rifkin, Arthur. "Obsessive-compulsive disorder." Postgraduate Medicine 86, no. 1 (July 1989): 157–68. http://dx.doi.org/10.1080/00325481.1989.11704332.

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18

Casey, David A. "Obsessive-compulsive disorder." Postgraduate Medicine 91, no. 2 (February 1992): 171–74. http://dx.doi.org/10.1080/00325481.1992.11701203.

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19

Hardy, Joelle Louise. "Obsessive Compulsive Disorder." Canadian Journal of Psychiatry 31, no. 3 (April 1986): 290. http://dx.doi.org/10.1177/070674378603100328.

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20

MURPHY, DENNIS L., MICHELE T. PATO, and TERESA A. PIGOTT. "Obsessive-Compulsive Disorder." Journal of Clinical Psychopharmacology 10, Supplement (June 1990): 91S—100S. http://dx.doi.org/10.1097/00004714-199006001-00016.

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21

Zetin, Mark, and Meagan A. Kramer. "Obsessive-Compulsive Disorder." Psychiatric Services 43, no. 7 (July 1992): 689–99. http://dx.doi.org/10.1176/ps.43.7.689.

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22

Veale, D., and A. Roberts. "Obsessive-compulsive disorder." BMJ 348, apr07 6 (April 7, 2014): g2183. http://dx.doi.org/10.1136/bmj.g2183.

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23

Taylor, Clare. "Obsessive—Compulsive Disorder." InnovAiT: Education and inspiration for general practice 2, no. 6 (June 2009): 358–63. http://dx.doi.org/10.1093/innovait/inp058.

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Obsessive—compulsive disorder is a common psychiatric disorder characterized by intrusive thoughts or ‘obsessions’, which predispose to repetitive acts or rituals, known as ‘compulsions’. These compulsions are necessary to relieve the anxiety caused by the obsession. Patients have insight into the unnecessary nature of the symptoms but can find them hard to suppress. Inability to carry out everyday activities can lead to significant functional impairment. Many feel embarrassed and go to great lengths to conceal the disorder from others which can lead to a delay in diagnosis and management.

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24

Jenike, Michael A. "Obsessive–Compulsive Disorder." New England Journal of Medicine 350, no. 3 (January 15, 2004): 259–65. http://dx.doi.org/10.1056/nejmcp031002.

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25

Grant, Jon E. "Obsessive–Compulsive Disorder." New England Journal of Medicine 371, no. 7 (August 14, 2014): 646–53. http://dx.doi.org/10.1056/nejmcp1402176.

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26

Kozak, Michael J. "Obsessive-compulsive disorder." Current Opinion in Psychiatry 7, no. 6 (November 1994): 475–79. http://dx.doi.org/10.1097/00001504-199411000-00010.

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27

Valente, Sharon M. "Obsessive-Compulsive Disorder." Perspectives in Psychiatric Care 38, no. 4 (October 12, 2002): 125–46. http://dx.doi.org/10.1111/j.1744-6163.2002.tb01563.x.

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28

SMITH, JEAN C., WILLIAM L. COLEMAN, CATHERINE L. GRUS, and ADRIAN D. SANDLER. "OBSESSIVE COMPULSIVE DISORDER." Journal of Developmental & Behavioral Pediatrics 17, no. 6 (December 1996): 437. http://dx.doi.org/10.1097/00004703-199612000-00024.

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29

Tallis, Frank. "Obsessive–Compulsive Disorder." British Journal of Psychiatry 166, no. 4 (April 1995): 546–50. http://dx.doi.org/10.1192/s0007125000074407.

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Obsessive–compulsive disorder (OCD) has recently undergone a dramatic change in status. Once regarded as a rare example of the neuroses, it now occupies a central position in contemporary psychiatry. The reasons for this renaissance in interest are relatively easy to describe. Firstly, results from the National Institute of Mental Health Epidemiological Catchment Area (ECA) survey indicated that the lifetime prevalence of OCD was 2.5% (1 in 40 people) and the 6-month point prevalence was 1.5%, making it the fourth most common psychiatric disorder in the US (Myers et al, 1984; Robins et al, 1984; Karno et al, 1988). If these figures are applicable to the UK, there may be up to 1 million sufferers. Secondly, the therapeutic efficacy of the selective serotonin reuptake inhibitors (SSRIs) and consistent findings from a number of neuroimaging investigations have stimulated interest in understanding the biological substrates of OCD. Finally, the traditional behavioural account of OCD has been elaborated, with greater emphasis given to cognition and cognitive processes; this revised anatomy of obsessions has, predictably, stimulated the development of specific cognitive therapy strategies.

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30

Richter, Peggy M. A., and Renato T. Ramos. "Obsessive-Compulsive Disorder." CONTINUUM: Lifelong Learning in Neurology 24 (June 2018): 828–44. http://dx.doi.org/10.1212/con.0000000000000603.

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31

Gorman, D. A., and E. Abi-Jaoude. "Obsessive-compulsive disorder." Canadian Medical Association Journal 186, no. 11 (March 24, 2014): E435. http://dx.doi.org/10.1503/cmaj.131257.

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32

Crino, Rocco D. "Obsessive compulsive disorder." International Review of Psychiatry 3, no. 2 (January 1991): 189–201. http://dx.doi.org/10.3109/09540269109110400.

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33

GEORGE, MARK S. "Obsessive–Compulsive Disorder." International Clinical Psychopharmacology 6 (December 1991): 57–68. http://dx.doi.org/10.1097/00004850-199112003-00006.

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34

Lydiard, R. B. "Obsessive-compulsive disorder." International Clinical Psychopharmacology 9 (June 1994): 33. http://dx.doi.org/10.1097/00004850-199406003-00006.

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35

Broatch, J. W. "Obsessive-compulsive disorder." International Clinical Psychopharmacology 11 (December 1996): 89. http://dx.doi.org/10.1097/00004850-199612005-00008.

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36

Mohammad, A. Majeed, N. A. Fineberg, and Lynne M. Drummond. "Obsessive-Compulsive Disorder." Medicine 28, no. 4 (2000): 15–17. http://dx.doi.org/10.1383/medc.28.4.15.28370.

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37

Heyman, I. "Obsessive-compulsive disorder." BMJ 333, no. 7565 (August 26, 2006): 424–29. http://dx.doi.org/10.1136/bmj.333.7565.424.

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38

Pary, Raymond, Steven Lippmann, and Carmelite R. Tobias. "Obsessive-compulsive disorder." Postgraduate Medicine 96, no. 8 (December 1994): 119–25. http://dx.doi.org/10.1080/00325481.1994.11945941.

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39

Greist, John H., and James W. Jefferson. "Obsessive-Compulsive Disorder." FOCUS 5, no. 3 (January 2007): 283–98. http://dx.doi.org/10.1176/foc.5.3.foc283.

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40

Bokor, Gyula, and Peter D. Anderson. "Obsessive–Compulsive Disorder." Journal of Pharmacy Practice 27, no. 2 (February 27, 2014): 116–30. http://dx.doi.org/10.1177/0897190014521996.

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Obsessive–compulsive disorder (OCD) is a common heterogeneous psychiatric disorder manifesting with obsessions and compulsions. Obsessions are intrusive, recurrent, and persistent unwanted thoughts. Compulsions are repetitive behaviors or mental acts that an individual feels driven to perform in response to the obsessions. The heterogeneity of OCD includes themes of obsessions, types of rituals, presence or absence of tics, etiology, genetics, and response to pharmacotherapy. Complications of OCD include interpersonal difficulties, unemployment, substance abuse, criminal justice issues, and physical injuries. Areas of the brain involved in the pathophysiology include the orbitofrontal cortex, anterior cingulate gyrus, and basal ganglia. Overall, OCD may be due to a malfunction in the cortico–striato–thalamo–cortical circuit in the brain. Neurotransmitters implicated in OCD include serotonin, dopamine, and glutamate. Numerous drugs such as atypical antipsychotics and dopaminergic agents can cause or exacerbate OCD symptoms. The etiology includes genetics and neurological insults. Treatment of OCD includes psychotherapy, pharmacotherapy, electroconvulsive therapy, transcranial magnetic simulation, and in extreme cases surgery. Exposure and response prevention is the most effective form of psychotherapy. Selective serotonin reuptake inhibitors (SSRIs) are the preferred pharmacotherapy. Higher doses than listed in the package insert and a longer trial are often needed for SSRIs than compared to other psychiatric disorders. Alternatives to SSRIs include clomipramine and serotonin/norepinephrine reuptake inhibitors. Treatment of resistant cases includes augmentation with atypical antipsychotics, pindolol, buspirone, and glutamate-blocking agents.

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41

Drubach, Daniel A. "Obsessive-Compulsive Disorder." CONTINUUM: Lifelong Learning in Neurology 21 (June 2015): 783–88. http://dx.doi.org/10.1212/01.con.0000466666.12779.07.

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42

Abramowitz, Jonathan S., Steven Taylor, and Dean McKay. "Obsessive-compulsive disorder." Lancet 374, no. 9688 (August 2009): 491–99. http://dx.doi.org/10.1016/s0140-6736(09)60240-3.

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43

Warnock, Julia K., and Thelda Kestenbaum. "OBSESSIVE-COMPULSIVE DISORDER." Dermatologic Clinics 14, no. 3 (July 1996): 465–72. http://dx.doi.org/10.1016/s0733-8635(05)70374-0.

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44

Miguel, Euripedes C., Scott L. Rauch, and Michael A. Jenike. "OBSESSIVE-COMPULSIVE DISORDER." Psychiatric Clinics of North America 20, no. 4 (December 1997): 863–83. http://dx.doi.org/10.1016/s0193-953x(05)70349-x.

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45

Stein, Dan J. "Obsessive-compulsive disorder." Lancet 360, no. 9330 (August 2002): 397–405. http://dx.doi.org/10.1016/s0140-6736(02)09620-4.

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46

Rauch, Scott L., Julianna F. Bates, and Igor D. Grachev. "Obsessive-Compulsive Disorder." Child and Adolescent Psychiatric Clinics of North America 6, no. 2 (April 1997): 365–82. http://dx.doi.org/10.1016/s1056-4993(18)30309-2.

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47

Leonard, Henrietta L., Marge C. Lenane, and Susan E. Swedo. "Obsessive-Compulsive Disorder." Child and Adolescent Psychiatric Clinics of North America 2, no. 4 (October 1993): 655–66. http://dx.doi.org/10.1016/s1056-4993(18)30531-5.

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48

Insel, Thomas R. "Obsessive-Compulsive Disorder." Psychiatric Clinics of North America 8, no. 1 (March 1985): 105–17. http://dx.doi.org/10.1016/s0193-953x(18)30712-3.

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49

Leonard, Henrietta L., Chelsea M. Ale, Jennifer B. Freeman, Abbe M. Garcia, and Janet S. Ng. "Obsessive-Compulsive Disorder." Child and Adolescent Psychiatric Clinics of North America 14, no. 4 (October 2005): 727–43. http://dx.doi.org/10.1016/j.chc.2005.06.002.

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50

Goodman, Wayne K., Dorothy E. Grice, Kyle A. B. Lapidus, and Barbara J. Coffey. "Obsessive-Compulsive Disorder." Psychiatric Clinics of North America 37, no. 3 (September 2014): 257–67. http://dx.doi.org/10.1016/j.psc.2014.06.004.

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