Academic literature on the topic 'OA Week 2016'
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Journal articles on the topic "OA Week 2016"
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Chang, Ssu-Yu, Yi-Jia Lin, Wei-Chun Hsu, Lin-Fen Hsieh, Yuan-Hsiang Lin, Chao-Chin Chang, You-Cai Chou, and Li-Fei Chen. "Exercise Alters Gait Pattern but Not Knee Load in Patients with Knee Osteoarthritis." BioMed Research International 2016 (2016): 1–12. http://dx.doi.org/10.1155/2016/7468937.
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Six female patients with bilateral medial knee OA and 6 healthy controls were recruited. Patients with knee OA received a 6-week physiotherapist-supervised and home-based exercise program. Outcome measures, including the Western Ontario and McMaster Universities Arthritis Index and Short Form-36 Health Survey as well as objective biomechanical indices were obtained at baseline and follow-up. After treatment, no significant difference was observed in the knee abductor moment (KAM), lever arm, and ground reaction force. We, however, observed significantly improved pain and physical function as well as altered gait patterns, including a higher hip flexor moment and hip extension angle with a faster walking speed. Although KAM was unchanged, patients with bilateral knee OA showed an improved walking speed and altered the gait pattern after 6 weeks of supervised exercise. This finding suggests that the exercise intervention improves proximal joint mechanics during walking and can be considered for patients with bilateral knee OA. Non-weight-bearing strengthening without external resistance combined with stretching exercise may be an option to improve pain and function in individuals with OA who cannot perform high resistance exercises owing to pain or other reasons.
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Berenbaum, Francis, Francisco J. Blanco, Ali Guermazi, Kenji Miki, Takaharu Yamabe, Lars Viktrup, Rod Junor, et al. "Subcutaneous tanezumab for osteoarthritis of the hip or knee: efficacy and safety results from a 24-week randomised phase III study with a 24-week follow-up period." Annals of the Rheumatic Diseases 79, no. 6 (March 31, 2020): 800–810. http://dx.doi.org/10.1136/annrheumdis-2019-216296.
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ObjectiveTanezumab, a nerve growth factor inhibitor, was investigated for osteoarthritis (OA) of the hip or knee in a study with 24-week treatment and 24-week safety follow-up.MethodsThis double-blind, randomised, phase III study enrolled adults in Europe and Japan with moderate-to-severe OA who had not responded to or could not tolerate standard-of-care analgesics. Patients were randomised to tanezumab 2.5 mg or 5 mg subcutaneously or matching placebo every 8 weeks (three doses). Co-primary end points were change from baseline to week 24 in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain and Physical Function, and Patient’s Global Assessment of OA (PGA-OA). Joint safety and neurological assessments continued throughout the 48-week study.ResultsFrom March 2016 to December 2017, 849 patients were randomised and evaluated (placebo n=282, tanezumab 2.5 mg n=283, tanezumab 5 mg n=284). At week 24, there was a statistically significant improvement from baseline for tanezumab 5 mg compared with placebo for WOMAC Pain (least squares mean difference±SE –0.62±0.18, p=0.0006), WOMAC Physical Function (–0.71±0.17, p<0.0001) and PGA-OA (–0.19±0.07, p=0.0051). For tanezumab 2.5 mg, there was a statistically significant improvement in WOMAC Pain and Physical Function, but not PGA-OA. Rapidly progressive osteoarthritis (RPOA) was observed in 1.4% (4/283) and 2.8% (8/284) of patients in the tanezumab 2.5 mg and tanezumab 5 mg groups, respectively and none receiving placebo. Total joint replacements (TJRs) were similarly distributed across all three treatment groups (6.7%–7.8%). Tanezumab-treated patients experienced more paraesthesia (5 mg) and hypoaesthesia (both doses) than placebo.ConclusionTanezumab 5 mg statistically significantly improved pain, physical function and PGA-OA, but tanezumab 2.5 mg only achieved two co-primary end points. RPOA occurred more frequently with tanezumab 5 mg than tanezumab 2.5 mg. TJRs were similarly distributed across all three groups.Trial registration numberNCT02709486.
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Emran, Mohammed, Md Israt Hasan, Syed Mozaffar Ahmed, Md Abu Shahin, Fatema Newaz, Badrunnessa Ahmed, Md Mahfuzul Alam, and Hasan Habibur Rahman. "Habitual Physical Exercise and Osteoarthritis of the Knee in Female." Bangladesh Medical Journal 48, no. 3 (February 2, 2021): 39–42. http://dx.doi.org/10.3329/bmj.v48i3.51796.
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The study aimed to evaluate the association of recreational (habitual) physical activities with the osteoarthritis (OA) of the knee in the female. The case-control study was carried out at the Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka in the year 2016 and 2017. The total participants were 174 female selected purposively with the age range of 40 – 70 years, among them 87 were the cases with OA of the knee, and the same number of the same age group were included as the control without OA of the knee. A structured interviewer-administered questionnaire was used to collect data. High level of physical activities (20 or more miles per week) was associated with OA of the knee, whereas moderate level of physical activities (10-20 miles/per week) and low level of physical activities (<10miles/per week) had no significant association with the OA of the knee. This study reveled the relationship of the physical activity and OA of the knee. Continue physical activity according to the public health guideline, may eliminate this such physical problem for the general health promotion and particularly to prevent the OA of the knee.
Bangladesh Med J. 2019 Sep; 48 (3): 39-42
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Yetisir, Fahri, Akgün Ebru Sarer, Hasan Zafer Acar, Gokhan Osmanoglu, Mehmet Özer, and Faik Yaylak. "Management of a Septic Open Abdomen Patient with Spontaneous Jejunal Perforation after Emergent C/S with Confounding Factor of Mild Acute Pancreatitis." Case Reports in Surgery 2016 (2016): 1–5. http://dx.doi.org/10.1155/2016/7153579.
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Introduction. We report the management of a septic Open Abdomen (OA) patient by the help of negative pressure therapy (NPT) and abdominal reapproximation anchor (ABRA) system in pregnant woman with spontaneous jejunal perforation after emergent cesarean section (C/S) with confounding factor of mild acute pancreatitis (AP).Presentation of Case. A 29-year-old and 34-week pregnant woman with AP underwent C/S. She was arrested after anesthesia induction and responded to cardiopulmonary resuscitation (CPR). There were only ash-colored serosanguinous fluid within abdomen during C/S. After C/S, she was transferred to intensive care unit (ICU) with vasopressor support. On postoperative 1st day, she underwent reoperation due to fecal fluid coming near the drainage. Leakage point could not be identified exactly and operation had to be deliberately abbreviated due to hemodynamic instability. NPT was applied. Two days later source control was provided by conversion of enteroatmospheric fistula (EAF) to jejunostomy. ABRA was added and OA was closed. No hernia developed at 10-month follow-up period.Conclusion. NPT application in septic OA patient may gain time to patient until adequate source control could be achieved. Using ABRA in conjunction with NPT increases the fascial closure rate in infected OA patient.
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Ryu, Mikyung, Sol Lee, Ho Kim, Weon-Chil Baek, and Heejin Kimm. "Effect of Aerobic Physical Activity on Health-Related Quality of Life in Middle Aged Women with Osteoarthritis: Korea National Health and Nutrition Examination Survey (2016–2017)." International Journal of Environmental Research and Public Health 17, no. 2 (January 14, 2020): 527. http://dx.doi.org/10.3390/ijerph17020527.
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Background: There have been few studies reporting the association between health-related quality of life (HRQoL) and osteoarthritis (OA) in female subjects performing aerobic exercise or not. The aim of this study is to compare HRQoL between OA patients and non-OA subjects in middle aged Korean women (40–59 years) with/without aerobic physical activity, and also to identify an association between EQ-5D instrument based HRQoL and OA controlling for aerobic exercise. Methods: This study used the cross-sectional data, the Korea National Health and Nutrition Examination Survey (KNANES) from 2016 to 2017. We only selected those who had completed the evaluations of aerobic physical activity and osteoarthritis diagnosis. In total, 2445 middle aged women were finally selected for this study. The European quality of life-5 dimensions (EQ-5D) was used for the evaluation of HRQoL as a dependent variable. In socio-demographic factors, age, sex, income level, education level, marital status, economic activity, type of insurance and private insurance and behaviour-related factors were included. One-way analysis of variance was conducted to compare the EQ-5D index and multiple linear regression analysis was employed to identify associated factors with the EQ-5D index. Results: In total, 2445 middle aged women were included in this study, in which 2209 participants were normal (90.0%) with aerobic physical activity (no: 55.0%, yes: 45.0%) and 246 participants were diagnosed with osteoarthritis (10.0%) with aerobic physical activity (no: 56.1%, yes: 43.9%). In group 2-2 (OA with aerobic), the moderate level of muscle exercise (less than 5 days per week) showed the highest HRQoL (p < 0.05) and high level exercise showed the lowest HRQoL (p < 0.05). In menopause status, the participants under menopause status showed lower HRQoL (p < 0.05) than those not under menopause status in group 2-2 (OA with aerobic) only. Conclusions: The HRQoL of OA patients was significantly lower than that of normal participants in middle aged Korean women (40–59 years). Especially, OA patients with maintained aerobic physical activity showed significantly higher HRQoL than those without that under controlling covariates such as age, income level, education level, marital status, economic activity, type of insurance, etc.
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Loo, Hou Chan, Fairuz Osman, Siew Lee Ho, Sing Yee An, Yim Mei Au Yong, and Ee Ming Khoo. "Incidence of angiotensin-converting enzyme inhibitor-induced cough in a Malaysian public primary care clinic: A retrospective cohort study." Malaysian Family Physician 17, no. 1 (March 22, 2022): 66–70. http://dx.doi.org/10.51866/oa.80.
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Introduction: The incidence of angiotensin-converting enzyme inhibitors (ACEi)-induced cough has been reported between 5% and 30% but is unknown in Malaysia. This study aimed to determine the incidence of ACEi-induced cough and its associated factors in a public primary care clinic in Malaysia. Methods: A retrospective review of electronic medical records of patients who were initiated ACEi between January 1, 2015, and December 31, 2015, and reviewed until July 31, 2016. A total of 1,091 patients were newly prescribed ACEi, and 394 patients were eligible for this study. We excluded patients who defaulted follow-ups with no further clinic visits before July 31, 2016, were transferred to the clinic without the recorded date of ACEi initiation, were transferred to other clinics during the study period, were followed up at other clinics and attended the study clinic for a short period, or were given only a stat dose of ACEi. Results: Among the 394 patients initiated on ACEi, 225 (57.1%) were male, 369 (93.7%) were Malay, 376 (95.4%) had hypertension, and 192 (48.7%) had diabetes. The incidence of ACEi-induced cough was 24.1%, and 42 (10.7%) patients developed cough on the day of therapy initiation. There was no association between age, gender, ethnicity, type of ACEi, and cough. Conclusion: Approximately one quarter of patients developed cough after ACEi initiation, and approximately half of them developed cough within 1 week of ACEi initiation. Doctors should consider early follow-up for patients initiated on ACEi therapy to ensure adherence, quality of life, and minimise unnecessary treatment.
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Hu, Weiwei, Brett B. Palm, Douglas A. Day, Pedro Campuzano-Jost, Jordan E. Krechmer, Zhe Peng, Suzane S. de Sá, et al. "Volatility and lifetime against OH heterogeneous reaction of ambient isoprene-epoxydiols-derived secondary organic aerosol (IEPOX-SOA)." Atmospheric Chemistry and Physics 16, no. 18 (September 19, 2016): 11563–80. http://dx.doi.org/10.5194/acp-16-11563-2016.
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Abstract. Isoprene-epoxydiols-derived secondary organic aerosol (IEPOX-SOA) can contribute substantially to organic aerosol (OA) concentrations in forested areas under low NO conditions, hence significantly influencing the regional and global OA budgets, accounting, for example, for 16–36 % of the submicron OA in the southeastern United States (SE US) summer. Particle evaporation measurements from a thermodenuder show that the volatility of ambient IEPOX-SOA is lower than that of bulk OA and also much lower than that of known monomer IEPOX-SOA tracer species, indicating that IEPOX-SOA likely exists mostly as oligomers in the aerosol phase. The OH aging process of ambient IEPOX-SOA was investigated with an oxidation flow reactor (OFR). New IEPOX-SOA formation in the reactor was negligible, as the OFR does not accelerate processes such as aerosol uptake and reactions that do not scale with OH. Simulation results indicate that adding ∼ 100 µg m−3 of pure H2SO4 to the ambient air allows IEPOX-SOA to be efficiently formed in the reactor. The heterogeneous reaction rate coefficient of ambient IEPOX-SOA with OH radical (kOH) was estimated as 4.0 ± 2.0 × 10−13 cm3 molec−1 s−1, which is equivalent to more than a 2-week lifetime. A similar kOH was found for measurements of OH oxidation of ambient Amazon forest air in an OFR. At higher OH exposures in the reactor (> 1 × 1012 molec cm−3 s), the mass loss of IEPOX-SOA due to heterogeneous reaction was mainly due to revolatilization of fragmented reaction products. We report, for the first time, OH reactive uptake coefficients (γOH = 0.59 ± 0.33 in SE US and γOH = 0.68 ± 0.38 in Amazon) for SOA under ambient conditions. A relative humidity dependence of kOH and γOH was observed, consistent with surface-area-limited OH uptake. No decrease of kOH was observed as OH concentrations increased. These observations of physicochemical properties of IEPOX-SOA can help to constrain OA impact on air quality and climate.
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Emran, Mohammed, Md Israt Hasan, Syed Mozaffar Ahmed, Fatema Newaz, Md Atiquzzaman, and Hasan Habibur Rahman. "Habitual physical exercise and osteoarthritis of the knee in female." Bangladesh Medical Research Council Bulletin 46, no. 2 (August 1, 2020): 99–103. http://dx.doi.org/10.3329/bmrcb.v46i2.49018.
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Background: The exercise is a widely promoted way to improve and maintain health, and osteoarthritis (OA) is a major health problem also. The study was conducted to examine the impact of different types of leisure-time physical activity on the OA of the knee.
Objective: The study was aimed to evaluate the association of recreational (habitual) physical activities with the osteoarthritis of the knee in the female.
Methods: The case-control study was carried out on 174 female selected purposively with the age range of 40 – 70 years and above, from September 2016 to August 2017.Among them 87 were the cases with OA of the knee, and the same number of healthy females of the same age group were included as the control. Physical activity was assessed by self-reported regular exercise patterns. A structured interviewer-administered questionnaire was used to collect data.
Results: Age, educational status, occupational status and BMI were not statistically significant (p>0.05) between the two groups. High level of physical activities (walking, running or jogging 20 or more miles per week) were associated with osteoarthritis of the knee, while low level of physical activities (<10miles/per week) and moderate level of physical activities (10-20 miles/per week) had no significant association with the osteoarthritis of the knee.
Conclusion: Based on the findings, the study suggests not to continue a high level of physical activities rather than to continue with moderate and low level of physical activity in accordance to subject’s physical propensity, and endorse this note for the general health promotion.
Bangladesh Med Res Counc Bull 2020; 46(2): 99-103
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Kimura, Seiji, Satoshi Yamaguchi, and Yoshimasa Ono. "Measurement of Physical Activity Level in Patients with Ankle Osteoarthritis." Foot & Ankle Orthopaedics 5, no. 4 (October 1, 2020): 2473011420S0030. http://dx.doi.org/10.1177/2473011420s00300.
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Category: Ankle Arthritis Introduction/Purpose: Maintaining physical activity (PA) is important for reducing the risk of lifestyle-related diseases and fundamental to keep healthy. PA is reduced in patients with knee and hip osteoarthritis, but PA of patients with ankle osteoarthritis has not been clarified. The purpose of this research is to compare PA level and proportion of patients who meet recommendations for health between ankle osteoarthritis and control patients. Methods: The subjects were 50 patients with ankle osteoarthritis (OA group), and 50 patients with minor hand disease matched by age and gender (control Group), who visited our outpatient clinic from October 2016 to April 2019. Both groups had 16 men and 34 women, with an average age of 68 years for the OA group and 66 years for the control group. The visual analogue scale for foot pain was 5.5 on average in the OA group and 0.3 in the control group. The physical activity for one week was measured using a tri-axial accelerometer. Unpaired t-tests were used to compare the number of steps per day and moderate or higher activity time between the OA group and the control group. The proportions of the OA group and the control group that met the recommendations set by Japan and the World Health Organization were compared using Fisher’s exact test. Results: The number of steps per day was 4177 +- 2312 steps in the OA group and 6802 +- 2851 steps in the control group, which was significantly lower in the OA group (p <0.001). Moderate PA time was 448 +- 232 minutes in the OA group and 634 +- 336 minutes in the control group, OA group was significantly lower (p = 0.02). Vigorous PA time was no difference between the two groups. The WHO recommendations were met by 45 patients in the OA group and 48 in the control group, no difference. The Japanese criterion were met by 33 patients in the OA group and 46 in the control group, which was significantly lower in the OA group (p = 0.001). Conclusion: PA of patients with ankle osteoarthritis was less than control patients. The proportion of patients meeting recommendations for health was lower in the OA group than the control group.
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Elser, Miriam, Ru-Jin Huang, Robert Wolf, Jay G. Slowik, Qiyuan Wang, Francesco Canonaco, Guohui Li, et al. "New insights into PM<sub>2.5</sub> chemical composition and sources in two major cities in China during extreme haze events using aerosol mass spectrometry." Atmospheric Chemistry and Physics 16, no. 5 (March 11, 2016): 3207–25. http://dx.doi.org/10.5194/acp-16-3207-2016.
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Abstract. During winter 2013–2014 aerosol mass spectrometer (AMS) measurements were conducted for the first time with a novel PM2.5 (particulate matter with aerodynamic diameter ≤ 2.5 µm) lens in two major cities of China: Xi'an and Beijing. We denote the periods with visibility below 2 km as extreme haze and refer to the rest as reference periods. During the measurements in Xi'an an extreme haze covered the city for about a week and the total non-refractory (NR)-PM2.5 mass fraction reached peak concentrations of over 1000 µg m−3. During the measurements in Beijing two extreme haze events occurred, but the temporal extent and the total concentrations reached during these events were lower than in Xi'an. Average PM2.5 concentrations of 537 ± 146 and 243 ± 47 µg m−3 (including NR species and equivalent black carbon, eBC) were recorded during the extreme haze events in Xi'an and Beijing, respectively. During the reference periods the measured average concentrations were 140 ± 99 µg m−3 in Xi'an and 75 ± 61 µg m−3 in Beijing. The relative composition of the NR-PM2.5 evolved substantially during the extreme haze periods, with increased contributions of the inorganic components (mostly sulfate and nitrate). Our results suggest that the high relative humidity present during the extreme haze events had a strong effect on the increase of sulfate mass (via aqueous phase oxidation of sulfur dioxide). Another relevant characteristic of the extreme haze is the size of the measured particles. During the extreme haze events, the AMS showed much larger particles, with a volume weighted mode at about 800 to 1000 nm, in contrast to about 400 nm during reference periods. These large particle sizes made the use of the PM2.5 inlet crucial, especially during the severe haze events, where 39 ± 5 % of the mass would have been lost in the conventional PM1 (particulate matter with aerodynamic diameter ≤ 1 µm) inlet. A novel positive matrix factorization procedure was developed to apportion the sources of organic aerosols (OA) based on their mass spectra using the multilinear engine (ME-2) controlled via the source finder (SoFi). The procedure allows for an effective exploration of the solution space, a more objective selection of the best solution and an estimation of the rotational uncertainties. Our results clearly show an increase of the oxygenated organic aerosol (OOA) mass during extreme haze events. The contribution of OOA to the total OA increased from the reference to the extreme haze periods from 16.2 ± 1.1 to 31.3 ± 1.5 % in Xi'an and from 15.7 ± 0.7 to 25.0 ± 1.2 % in Beijing. By contrast, during the reference periods the total OA mass was dominated by domestic emissions of primary aerosols from biomass burning in Xi'an (42.2 ± 1.5 % of OA) and coal combustion in Beijing (55.2 ± 1.6 % of OA). These two sources are also mostly responsible for extremely high polycyclic aromatic hydrocarbon (PAH) concentrations measured with the AMS (campaign average of 2.1 ± 2.0 µg m−3 and frequent peak concentrations above 10 µg m−3). To the best of our knowledge, this is the first data set where the simultaneous extraction of these two primary sources could be achieved in China by conducting on-line AMS measurements at two areas with contrasted emission patterns.
Conference papers on the topic "OA Week 2016"
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Baer, Thomas, Ryan Frisbie, Michael Willey, and Jessica Goetz. "Development of a Simplified Ankle Distractor." In 2017 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/dmd2017-3438.
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The physical impairment caused by OA of a single lower extremity joint is comparable to that reported for major life-altering disorders such as end-stage kidney disease and heart failure. (Buckwalter, et al) [1] Ankle distraction arthroplasty has been shown to greatly decrease pain due to end-stage ankle arthritis. Unlike arthrodesis (fusion of the joint), distraction arthroplasty maintains the joint’s natural movement, and it is far less complicated than total joint replacement surgery. There is a considerable body of research supporting the idea that distraction of an end-stage arthritic joint (most of the work thus far has been done on ankles, although there has also been some investigation of the efficacy of the treatment for knee arthritis) for a period of weeks allows the growth of new tissue in the joint. Although this tissue is not true articular cartilage, distraction arthroplasty has been shown to significantly decrease pain and, in the majority of cases, to be a long lasting remedy for a condition that would otherwise commonly be treated with arthrodesis. [2] Devices currently available for this procedure are generally quite complicated because they are designed for a wide range of functions related to bone fixation. This versatility also tends to make those systems larger and more expensive, and their aggressively mechanical appearance makes potential joint distraction patients hesitant to select the procedure. While fracture patients may not have a choice about being treated with such devices, elective patients are instinctively resistant to their use, even when assured that the end result will most likely significantly improve in the quality of their lives.
Reports on the topic "OA Week 2016"
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Li, Chan, Becky Miller, and Mohamed Hamed. Library Impact Research Report: Open Access Publishing: A Study of UC Berkeley Faculty Views and Practices. Association of Research Libraries, January 2023. http://dx.doi.org/10.29242/report.ucberkeley2023.
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As part of ARL’s Research Library Impact Framework initiative, a team at the University of California (UC) Berkeley Library studied the relationship between faculty’s attitudes toward open access (OA) and their OA publishing practices, including the roles of funding availability and discipline. The project team compared UC Berkeley faculty’s answers to questions related to OA from the 2018 Ithaka S+R Faculty Survey with the faculty’s scholarly output in the Scopus database. The study focused on gold OA articles, which usually require authors to pay article processing charges (APCs) and which accounted for 18% of the publications in the sample. Overall, the UC Berkeley study found a positive correlation between publishing gold OA and the faculty’s support for OA (no cost to read). In contrast, the correlation between publishing gold OA and the faculty’s concern about publishing cost was weak. Publishing costs concerned faculty in all subject areas, whether or not their articles reported research funding. Thus, UC Berkeley Library’s efforts to pursue transformative publishing agreements and prioritize funding for a program subsidizing publishing fees seem like effective strategies to increase OA.