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Journal articles on the topic 'NSR100'

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Author: Grafiati

Published: 9 March 2023

Last updated: 10 March 2023

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1

Fischer-Shofty, Meytal, Yechiel Levkovitz, and Simone G. Shamay-Tsoory. "Oxytocin facilitates accurate perception of competition in men and kinship in women." Social Cognitive and Affective Neuroscience 8, no. 3 (March 24, 2012): 313–17. http://dx.doi.org/10.1093/scan/nsr100.

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2

Quesnel-Vallières, Mathieu, Manuel Irimia, Sabine P. Cordes, and Benjamin J. Blencowe. "Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development." Genes & Development 29, no. 7 (April 1, 2015): 746–59. http://dx.doi.org/10.1101/gad.256115.114.

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3

Capponi, Simona, Nadja Stöffler, Manuel Irimia, Frederik M. A. Van Schaik, Mercedes M. Ondik, Martin L. Biniossek, Lisa Lehmann, et al. "Neuronal-specific microexon splicing of TAF1 mRNA is directly regulated by SRRM4/nSR100." RNA Biology 17, no. 1 (September 27, 2019): 62–74. http://dx.doi.org/10.1080/15476286.2019.1667214.

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4

Shimojo, Masahito, Yoshie Shudo, Masatoshi Ikeda, Tomoyo Kobashi, and Seiji Ito. "The Small Cell Lung Cancer-Specific Isoform of RE1-Silencing Transcription Factor (REST) Is Regulated By Neural-Specific Ser/Arg Repeat-Related Protein of 100 kDa (nSR100)." Molecular Cancer Research 11, no. 10 (August 8, 2013): 1258–68. http://dx.doi.org/10.1158/1541-7786.mcr-13-0269.

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5

Boksem, Maarten A. S., Evelien Kostermans, Branka Milivojevic, and David De Cremer. "Social status determines how we monitor and evaluate our performance." Social Cognitive and Affective Neuroscience 7, no. 3 (March 18, 2011): 304–13. http://dx.doi.org/10.1093/scan/nsr010.

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6

Kim, Chang-Hyun, Sang-Moo Park, Sun-jae Lee, Young-Dae Kim, Se-Hwan Jang, Seon-Min Woo, Taeg-Kyu Kwon, et al. "NSrp70 is a lymphocyte-essential splicing factor that controls thymocyte development." Nucleic Acids Research 49, no. 10 (May 25, 2021): 5760–78. http://dx.doi.org/10.1093/nar/gkab389.

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Abstract Alternative pre-mRNA splicing is a critical step to generate multiple transcripts, thereby dramatically enlarging the proteomic diversity. Thus, a common feature of most alternative splicing factor knockout models is lethality. However, little is known about lineage-specific alternative splicing regulators in a physiological setting. Here, we report that NSrp70 is selectively expressed in developing thymocytes, highest at the double-positive (DP) stage. Global splicing and transcriptional profiling revealed that NSrp70 regulates the cell cycle and survival of thymocytes by controlling the alternative processing of various RNA splicing factors, including the oncogenic splicing factor SRSF1. A conditional-knockout of Nsrp1 (NSrp70-cKO) using CD4Cre developed severe defects in T cell maturation to single-positive thymocytes, due to insufficient T cell receptor (TCR) signaling and uncontrolled cell growth and death. Mice displayed severe peripheral lymphopenia and could not optimally control tumor growth. This study establishes a model to address the function of lymphoid-lineage-specific alternative splicing factor NSrp70 in a thymic T cell developmental pathway.

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7

Lieberman, Matthew D. "SCAN heads to kindergarten." Social Cognitive and Affective Neuroscience 6, no. 1 (January 1, 2011): 1. http://dx.doi.org/10.1093/scan/nsr001.

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8

Wang, Gang, Lihua Mao, Yina Ma, Xuedong Yang, Jingqian Cao, Xi Liu, Jinzhao Wang, Xiaoying Wang, and Shihui Han. "Neural representations of close others in collectivistic brains." Social Cognitive and Affective Neuroscience 7, no. 2 (March 7, 2011): 222–29. http://dx.doi.org/10.1093/scan/nsr002.

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9

Eldaief, Mark C., Thilo Deckersbach, Lindsay E. Carlson, Jan C. Beucke, and Darin D. Dougherty. "Emotional and cognitive stimuli differentially engage the default network during inductive reasoning." Social Cognitive and Affective Neuroscience 7, no. 4 (February 4, 2011): 380–92. http://dx.doi.org/10.1093/scan/nsr003.

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10

Avenanti, Alessio, and Cosimo Urgesi. "Understanding ‘what’ others do: mirror mechanisms play a crucial role in action perception." Social Cognitive and Affective Neuroscience 6, no. 3 (June 1, 2011): 257–59. http://dx.doi.org/10.1093/scan/nsr004.

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11

Kahane, Guy, Katja Wiech, Nicholas Shackel, Miguel Farias, Julian Savulescu, and Irene Tracey. "The neural basis of intuitive and counterintuitive moral judgment." Social Cognitive and Affective Neuroscience 7, no. 4 (March 18, 2011): 393–402. http://dx.doi.org/10.1093/scan/nsr005.

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12

Lin, Alice, Ralph Adolphs, and Antonio Rangel. "Social and monetary reward learning engage overlapping neural substrates." Social Cognitive and Affective Neuroscience 7, no. 3 (March 22, 2011): 274–81. http://dx.doi.org/10.1093/scan/nsr006.

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13

Olvet, Doreen M., and Greg Hajcak. "The error-related negativity relates to sadness following mood induction among individuals with high neuroticism." Social Cognitive and Affective Neuroscience 7, no. 3 (March 7, 2011): 289–95. http://dx.doi.org/10.1093/scan/nsr007.

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14

Tassy, Sébastien, Olivier Oullier, Yann Duclos, Olivier Coulon, Julien Mancini, Christine Deruelle, Sharam Attarian, Olivier Felician, and Bruno Wicker. "Disrupting the right prefrontal cortex alters moral judgement." Social Cognitive and Affective Neuroscience 7, no. 3 (April 22, 2011): 282–88. http://dx.doi.org/10.1093/scan/nsr008.

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15

Dhont, Kristof, Alain Van Hiel, Sven Pattyn, Emma Onraet, and Els Severens. "A step into the anarchist’s mind: examining political attitudes and ideology through event-related brain potentials." Social Cognitive and Affective Neuroscience 7, no. 3 (March 18, 2011): 296–303. http://dx.doi.org/10.1093/scan/nsr009.

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16

Sessa, Paola, Silvia Tomelleri, Roy Luria, Luigi Castelli, Michael Reynolds, and Roberto Dell’Acqua. "Look out for strangers! Sustained neural activity during visual working memory maintenance of other-race faces is modulated by implicit racial prejudice." Social Cognitive and Affective Neuroscience 7, no. 3 (July 18, 2011): 314–21. http://dx.doi.org/10.1093/scan/nsr011.

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17

Hortensius, Ruud, Dennis J. L. G. Schutter, and Eddie Harmon-Jones. "When anger leads to aggression: induction of relative left frontal cortical activity with transcranial direct current stimulation increases the anger–aggression relationship." Social Cognitive and Affective Neuroscience 7, no. 3 (March 18, 2011): 342–47. http://dx.doi.org/10.1093/scan/nsr012.

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18

Amemiya, Shiori, and Kuni Ohtomo. "Effect of the observed pupil size on the amygdala of the beholders." Social Cognitive and Affective Neuroscience 7, no. 3 (March 18, 2011): 332–41. http://dx.doi.org/10.1093/scan/nsr013.

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19

Gyurak, Anett, Christine I. Hooker, Asako Miyakawa, Sara Verosky, Anna Luerssen, and Özlem N. Ayduk. "Individual differences in neural responses to social rejection: the joint effect of self-esteem and attentional control." Social Cognitive and Affective Neuroscience 7, no. 3 (May 23, 2011): 322–31. http://dx.doi.org/10.1093/scan/nsr014.

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20

Bhanji, Jamil P., and Jennifer S. Beer. "Unpacking the neural associations of emotion and judgment in emotion-congruent judgment." Social Cognitive and Affective Neuroscience 7, no. 3 (April 21, 2011): 348–56. http://dx.doi.org/10.1093/scan/nsr015.

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21

Fitzgibbon, Bernadette M., Peter G. Enticott, Melita J. Giummarra, Richard H. Thomson, Nellie Georgiou-Karistianis, and John L. Bradshaw. "Atypical electrophysiological activity during pain observation in amputees who experience synaesthetic pain." Social Cognitive and Affective Neuroscience 7, no. 3 (May 12, 2011): 357–68. http://dx.doi.org/10.1093/scan/nsr016.

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22

Rilling, James K., Jan Scholz, Todd M. Preuss, Matthew F. Glasser, Bhargav K. Errangi, and Timothy E. Behrens. "Differences between chimpanzees and bonobos in neural systems supporting social cognition." Social Cognitive and Affective Neuroscience 7, no. 4 (April 5, 2011): 369–79. http://dx.doi.org/10.1093/scan/nsr017.

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23

Simmons, W. Kyle, and Alex Martin. "Spontaneous resting-state BOLD fluctuations reveal persistent domain-specific neural networks." Social Cognitive and Affective Neuroscience 7, no. 4 (May 17, 2011): 467–75. http://dx.doi.org/10.1093/scan/nsr018.

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24

Nielsen, Lisbeth, and Mara Mather. "Emerging perspectives in social neuroscience and neuroeconomics of aging." Social Cognitive and Affective Neuroscience 6, no. 2 (April 2011): 149–64. http://dx.doi.org/10.1093/scan/nsr019.

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25

Gunther Moor, Bregtje, Zdeňa A. Op de Macks, Berna Güroğlu, Serge A. R. B. Rombouts, Maurits W. Van der Molen, and Eveline A. Crone. "Neurodevelopmental changes of reading the mind in the eyes." Social Cognitive and Affective Neuroscience 7, no. 1 (April 22, 2011): 44–52. http://dx.doi.org/10.1093/scan/nsr020.

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26

Severens, Els, Simone Kühn, Robert J. Hartsuiker, and Marcel Brass. "Functional mechanisms involved in the internal inhibition of taboo words." Social Cognitive and Affective Neuroscience 7, no. 4 (May 23, 2011): 431–35. http://dx.doi.org/10.1093/scan/nsr030.

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27

Clayson, Peter E., Ann Clawson, and Michael J. Larson. "The effects of induced state negative affect on performance monitoring processes." Social Cognitive and Affective Neuroscience 7, no. 6 (June 17, 2011): 677–88. http://dx.doi.org/10.1093/scan/nsr040.

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28

Owens, Max, Ernst H. W. Koster, and Nazanin Derakshan. "Impaired filtering of irrelevant information in dysphoria: an ERP study." Social Cognitive and Affective Neuroscience 7, no. 7 (September 6, 2011): 752–63. http://dx.doi.org/10.1093/scan/nsr050.

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29

Hofman, Dennis, and Dennis J. L. G. Schutter. "Asymmetrical frontal resting-state beta oscillations predict trait aggressive tendencies and behavioral inhibition." Social Cognitive and Affective Neuroscience 7, no. 7 (October 20, 2011): 850–57. http://dx.doi.org/10.1093/scan/nsr060.

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30

McMillan, Corey T., Katya Rascovsky, M. Catherine Khella, Robin Clark, and Murray Grossman. "The neural basis for establishing a focal point in pure coordination games." Social Cognitive and Affective Neuroscience 7, no. 8 (October 18, 2011): 881–87. http://dx.doi.org/10.1093/scan/nsr070.

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31

Paul, Victoria Gabriele, Astrid Veronika Rauch, Harald Kugel, Lena ter Horst, Jochen Bauer, Udo Dannlowski, Patricia Ohrmann, et al. "High responsivity to threat during the initial stage of perception in repression: a 3 T fMRI study." Social Cognitive and Affective Neuroscience 7, no. 8 (December 1, 2011): 980–90. http://dx.doi.org/10.1093/scan/nsr080.

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32

Mende-Siedlecki, Peter, Christopher P. Said, and Alexander Todorov. "The social evaluation of faces: a meta-analysis of functional neuroimaging studies." Social Cognitive and Affective Neuroscience 8, no. 3 (January 27, 2012): 285–99. http://dx.doi.org/10.1093/scan/nsr090.

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33

Lee, W. C., D. Zabetakis, and T. Mélèse. "NSR1 is required for pre-rRNA processing and for the proper maintenance of steady-state levels of ribosomal subunits." Molecular and Cellular Biology 12, no. 9 (September 1992): 3865–71. http://dx.doi.org/10.1128/mcb.12.9.3865-3871.1992.

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NSR1 is a yeast nuclear localization sequence-binding protein showing striking similarity in its domain structure to nucleolin. Cells lacking NSR1 are viable but have a severe growth defect. We show here that NSR1, like nucleolin, is involved in ribosome biogenesis. The nsr1 mutant is deficient in pre-rRNA processing such that the initial 35S pre-rRNA processing is blocked and 20S pre-rRNA is nearly absent. The reduced amount of 20S pre-rRNA leads to a shortage of 18S rRNA and is reflected in a change in the distribution of 60S and 40S ribosomal subunits; there is no free pool of 40S subunits, and the free pool of 60S subunits is greatly increased in size. The lack of free 40S subunits or the improper assembly of these subunits causes the nsr1 mutant to show sensitivity to the antibiotic paromomycin, which affects protein translation, at concentrations that do not affect the growth of the wild-type strain. Our data support the idea that NSR1 is involved in the proper assembly of pre-rRNA particles, possibly by bringing rRNA and ribosomal proteins together by virtue of its nuclear localization sequence-binding domain and multiple RNA recognition motifs. Alternatively, NSR1 may also act to regulate the nuclear entry of ribosomal proteins required for proper assembly of pre-rRNA particles.

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34

Lee, W. C., D. Zabetakis, and T. Mélèse. "NSR1 is required for pre-rRNA processing and for the proper maintenance of steady-state levels of ribosomal subunits." Molecular and Cellular Biology 12, no. 9 (September 1992): 3865–71. http://dx.doi.org/10.1128/mcb.12.9.3865.

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NSR1 is a yeast nuclear localization sequence-binding protein showing striking similarity in its domain structure to nucleolin. Cells lacking NSR1 are viable but have a severe growth defect. We show here that NSR1, like nucleolin, is involved in ribosome biogenesis. The nsr1 mutant is deficient in pre-rRNA processing such that the initial 35S pre-rRNA processing is blocked and 20S pre-rRNA is nearly absent. The reduced amount of 20S pre-rRNA leads to a shortage of 18S rRNA and is reflected in a change in the distribution of 60S and 40S ribosomal subunits; there is no free pool of 40S subunits, and the free pool of 60S subunits is greatly increased in size. The lack of free 40S subunits or the improper assembly of these subunits causes the nsr1 mutant to show sensitivity to the antibiotic paromomycin, which affects protein translation, at concentrations that do not affect the growth of the wild-type strain. Our data support the idea that NSR1 is involved in the proper assembly of pre-rRNA particles, possibly by bringing rRNA and ribosomal proteins together by virtue of its nuclear localization sequence-binding domain and multiple RNA recognition motifs. Alternatively, NSR1 may also act to regulate the nuclear entry of ribosomal proteins required for proper assembly of pre-rRNA particles.

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35

Molina Herrera, Maritzabel, and Xavier Fernando Hurtado Amézquita. "Formulating a design for a screw-type shear connector in a composite section." Ingeniería e Investigación 31, no. 2 (May 1, 2011): 52–64. http://dx.doi.org/10.15446/ing.investig.v31n2.23465.

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Screws-type shear connectors have been most used in Colombia during the last decade; however, an expression for their design in composite sections has only recently been presented (NSR10, paragraph F.2.9.8.2.2). This paper outlines shear design formulation development for screw connectors, analysing the influence of different composite section behaviour parameters. This research studied 18 composite section models using two 42MPa concrete slabs having different arrangements of 1/2", 5/8" or 3/4" diameter 1, 2 or 3 screw shear connectors and 0.08m, 0.12m or 0.14m spacing between connectors. Three specimens were tested by push-out for each model. The laboratory results using the methodology proposed by Ollgaard revealed connector diameter and spacing influence on the model’s behaviour. A design formulation for screws in composite sections is presented.

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36

Lee, W. C., Z. X. Xue, and T. Mélèse. "The NSR1 gene encodes a protein that specifically binds nuclear localization sequences and has two RNA recognition motifs." Journal of Cell Biology 113, no. 1 (April 1, 1991): 1–12. http://dx.doi.org/10.1083/jcb.113.1.1.

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We previously identified a protein (p67) in the yeast, Saccharomyces cerevisiae, that specifically recognizes nuclear localization sequences. We report here the partial purification of p67, and the isolation, sequencing, and disruption of the gene (NSR1) encoding this protein. p67 was purified using an affinity column conjugated with a peptide containing the histone H2B nuclear localization sequence from yeast. Using antibodies against p67 we have cloned the gene for this protein. The protein encoded by the NSR1 gene recognizes the wild-type H2B nuclear localization sequence, but does not recognize a mutant H2B sequence that is incompetent for nuclear localization in vivo. Interestingly, the NSR1 protein has two RNA recognition motifs, as well as an acidic NH2 terminus containing a series of serine clusters, and a basic COOH terminus containing arg-gly repeats. We have confirmed the nuclear localization of p67 by immunofluorescence and found that a restricted portion of the nucleus is highlighted. We have also shown that NSR1 (p67) is required for normal cell growth.

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37

Singh, Shivani, Alexandra Berroyer, Minseon Kim, and Nayun Kim. "Yeast Nucleolin Nsr1 Impedes Replication and Elevates Genome Instability at an Actively Transcribed Guanine-Rich G4 DNA-Forming Sequence." Genetics 216, no. 4 (October 26, 2020): 1023–37. http://dx.doi.org/10.1534/genetics.120.303736.

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A significant increase in genome instability is associated with the conformational shift of a guanine-run-containing DNA strand into the four-stranded G-quadruplex (G4) DNA. The mechanism underlying the recombination and genome rearrangements following the formation of G4 DNA in vivo has been difficult to elucidate but has become better clarified by the identification and functional characterization of several key G4 DNA-binding proteins. Mammalian nucleolin (NCL) is a highly specific G4 DNA-binding protein with a well-defined role in the transcriptional regulation of genes with associated G4 DNA-forming sequence motifs at their promoters. The consequence of the in vivo interaction between G4 DNA and nucleolin in respect to the genome instability has not been previously investigated. We show here that the yeast nucleolin Nsr1 is enriched at a G4 DNA-forming sequence in vivo and is a major factor in inducing the genome instability associated with the cotranscriptionally formed G4 DNA in the yeast genome. We also show that Nsr1 results in impeding replication past such a G4 DNA-forming sequence. The G4-associated genome instability and the G4 DNA-binding in vivo require the arginine-glycine-glycine (RGG) repeats located at the C-terminus of the Nsr1 protein. Nsr1 with the deletion of RGG domain supports normal cell growth and is sufficient for its pre-rRNA processing function. However, the truncation of the RGG domain of Nsr1 significantly weakens its interaction with G4 DNA in vivo and restores unhindered replication, overall resulting in a sharp reduction in the genome instability associated with a guanine-rich G4 DNA-forming sequence. Our data suggest that the interaction between Nsr1 with the intact RGG repeats and G4 DNA impairs genome stability by precluding the access of G4-resolving proteins and impeding replication.

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38

Yan, C., and T. Mélèse. "Multiple regions of NSR1 are sufficient for accumulation of a fusion protein within the nucleolus." Journal of Cell Biology 123, no. 5 (December 1, 1993): 1081–91. http://dx.doi.org/10.1083/jcb.123.5.1081.

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NSR1, a 67-kD nucleolar protein, was originally identified in our laboratory as a nuclear localization signal binding protein, and has subsequently been found to be involved in ribosome biogenesis. NSR1 has three regions: an acidic/serine-rich NH2 terminus, two RNA recognition motifs, and a glycine/arginine-rich COOH terminus. In this study we show that NSR1 itself has a bipartite nuclear localization sequence. Deletion of either basic amino acid stretch results in the mislocation of NSR1 to the cytoplasm. We further demonstrate that either of two regions, the NH2 terminus or both RNA recognition motifs, are sufficient to localize a bacterial protein, beta-galactosidase, to the nucleolus. Intensive deletion analysis has further defined a specific acidic/serine-rich region within the NH2 terminus as necessary for nucleolar accumulation rather than nucleolar targeting. In addition, deletion of either RNA recognition motif or point mutations in one of the RNP consensus octamers results in the mislocalization of a fusion protein within the nucleus. Although the glycine/arginine-rich region in the COOH terminus is not sufficient to bring beta-galactosidase to the nucleolus, our studies show that this domain is necessary for nucleolar accumulation when an RNP consensus octamer in one of the RNA recognition motifs is mutated. Our findings are consistent with the notion that nucleolar localization is a result of the binding interactions of various domains of NSR1 within the nucleolus rather than the presence of a specific nucleolar targeting signal.

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39

Takeuchi T., Caori, Mauricio Duarte T., John E. Alarcón G, and Jairo F. Olarte F. "Estudio multifactorial de resistencia ultima a tensión paralela a la fibra en muestras de guadua angustifolia Kunth." Ingeniería y Región 11, no. 1 (June 30, 2014): 85. http://dx.doi.org/10.25054/22161325.745.

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Este artículo presenta la relación de la resistencia última a tensión paralela a la fibra de probetas de Guadua angustifolia procedentes de cuatro zonas del municipio de Pitalito-Huila, con factores como sección inferior, medio o superior y zona, determinada mediante un análisis de varianza multifactorial. La metodología para el corte de los culmos, obtención de las probetas y pruebas de resistencia a tensión, se basó en las normas NTC5300, NTC5525, NSR10 e ISO/TC 165N315, y en los protocolos para corte de culmos, probetas y determinación de la resistencia a tensión paralela a la fibra de la Universidad Nacional de Colombia sede Bogotá. Fueron ensayadas 120 probetas en la Universidad Nacional de Colombia sede Bogotá. El promedio de resistencia a la tensión paralela fue de 61,0 Mpa. El análisis multifactorial del diseño experimental, permitió identificar la significancia estadística de los factores sección y zona sobre la resistencia a la tensión con un valor-p inferior a 0,05 y un nivel de confianza del 95%, la interacción de segundo orden no fue significativo.

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40

Ivenin, A. V., A. P. Sakov, Yu A. Bogomolovа, T. S. Вuzynina, and V. V. Ivenin. "The effect of mineral fertilizers and long-term aftereffect of liming on the biological properties of light gray forest soil and the yield of meadow clover 1g .p. in the conditions of the South-East of the Volga-Vyatka region." Agrarian science, no. 7-8 (September 24, 2021): 119–22. http://dx.doi.org/10.32634/0869-8155-2021-351-7-8-119-122.

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The article deals with the influence of mineral fertilizers and the long-term aftereffect of liming on the biological properties of light gray forest soil and the yield of meadow clover 1 g.p. in the conditions of the South-East of the Volga-Vyatka region. The biological properties of light gray forest soil in 2020 were more influenced by the weather conditions of the pink clover vegetation and the culture itself than by the studied aftereffects of lime material and various doses of its mineral nutrition. The biological activity of the soil was in the range of 16.3–30.4%. The intensity of soil respiration was very weak and was in the range of 1.53–3.4 mg of CO2/10g for 24 hours. The average yield of the green mass of clover 1 g.p. (in terms of absolutely dry matter) was in the range of 30.4–33.2 t/ha (NSR05 by factor B-6.3) and did not depend on the aftereffect of the studied lime doses. The use of N45P120K180 doses of mineral fertilizers increases the average yield of pink clover 1 g.p. compared with the natural fertility of light gray forest soil and the variants of using N15P40K60 doses up to 37.9 t/ ha, which is by11.9 and 8.6 t/ha respectively higher than these variants (NSR05 for factor A-5.2). An increase was also obtained from the use of N30P80K120 doses of mineral fertilizers compared to the cultivation of clover according to natural soil fertility — by7.4 t/ha (NSR05 according to factor A-5.2).I n general, for 42 years of studying the aftereffect of liming it was shown, that by 2020 liming does not affect the biological properties of light gray forest soil and the yield of 1 g.p. clove according to all the studied doses of its use in the conditions of the South-East of the Volga-Vyatka region. The soil needs repeating of reclamation works.

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41

Ruíz, Andrés Felipe, and Carlos Javier Peñaranda. "Evaluación de mezclas de arcilla adicionando componentes tecnológicos para la fabricación de bloques de construcción." Sostenibilidad, Tecnología y Humanismo 11, no. 2 (July 1, 2020): 50–61. http://dx.doi.org/10.25213/2216-1872.95.

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La construcción ha estado en busca de la optimización de sus procesos y en el mejoramiento de los materiales y sus aplicaciones a través de la reutilización de productos como complementos para el mejoramiento de los materiales de construcción con el fin de generar una construcción sostenible que sea amigable con el medio ambiente, como lo plantea la economía circular la cual es un concepto relacionado con el aprovechamiento de los recursos. Una economía lineal plantea el aprovechamiento de los recursos desde un principio hasta un final, mientras que la circular trata de reutilizarlos insertándolos de nuevo en el proceso, esto podría entenderse también como la optimización del ciclo de vida. El presente artículo describe la evaluación de componentes tecnológicos utilizados en la mezcla de la elaboración de bloques de arcilla de construcción, tales como hojas de árboles y ceniza de raquis de palma africana, teniendo como objetivo estimar su factibilidad en costos y realizar un diagnóstico de las diferentes propiedades que proporcionan estos componentes a la mezcla, así como los requisitos que deben cumplir los bloques de arcilla según la norma sismorresistente colombiana NSR10.

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42

Gamberi, Chiara, Giovanna Contreas, Maria Grazia Romanelli, and Carlo Morandi. "Analysis of the yeast NSR1 gene and protein domain comparison between Nsr1 and human hnRNP type A1." Gene 148, no. 1 (October 1994): 59–66. http://dx.doi.org/10.1016/0378-1119(94)90233-x.

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43

Takeuchi T, Caori, Mauricio Duarte T., Andrés F. Capera O., and Wilson J. Erazo E. "Análisis de varianza multifactorial para resistencia última a la compresión paralela a la fibra en muestras de Guadua Angustifolia Kunth." Ingeniería y Región 9 (December 30, 2012): 53–61. http://dx.doi.org/10.25054/22161325.775.

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Se presenta la evaluación del comportamiento de la resistencia a la compresión paralela a la fibra de probetas de Guadua angustifolia en relación a factores como zona, sección del culmo o tallo y presencia de nudo, realizada mediante un análisis de varianza multifactorial. Las muestras objeto de estudio procedentes de cuatro zonas ubicadas en el municipio de Pitalito y una en el municipio de Timaná al sur del departamento del Huila, fueron ensayadas en el Instituto de Extensión e Investigación (IEI) de la Universidad Nacional de Colombia sede Bogotá. La metodología para el corte de los culmos, obtención de las probetas y ensayos de resistencia a la compresión, se basó en las normas NTC5300, NTC5525, NSR10 e ISO/TC 165N315, y en los protocolos para corte de culmos y probetas, y determinación de la resistencia a la compresión paralela a la fibra de la Universidad Nacional de Colombia sede Bogotá. La resistencia a la compresión paralela a la fibra promedio de 130 probetas fue de 38,0 Mpa. El análisis de varianza multifactorial del diseño experimental, permitió identificar la significancia estadística del factor sección sobre la resistencia a la compresión con un valor-p inferior a 0,05 y un nivel de confianza del 95%, los valores más altos se encontraron para la parte superior. Los factores zona y presencia de nudo, al igual que las interacciones de segundo orden no fueron significativos.

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Kim, Young-Dae, Jung-Yoon Lee, Kyu-Man Oh, Masatake Araki, Kimi Araki, Ken-ichi Yamamura, and Chang-Duk Jun. "NSrp70 is a novel nuclear speckle-related protein that modulates alternative pre-mRNA splicing in vivo." Nucleic Acids Research 39, no. 10 (February 3, 2011): 4300–4314. http://dx.doi.org/10.1093/nar/gkq1267.

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Lee, Soo-Ho, Chowon Kim, Hyun-Kyung Lee, Yoo-Kyung Kim, Tayaba Ismail, Youngeun Jeong, Kyungyeon Park, Mae-Ja Park, Do-Sim Park, and Hyun-Shik Lee. "NSrp70 is significant for embryonic growth and development, being a crucial factor for gastrulation and mesoderm induction." Biochemical and Biophysical Research Communications 479, no. 2 (October 2016): 238–44. http://dx.doi.org/10.1016/j.bbrc.2016.09.051.

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Jiang, Yi, Zhenghe Li, and Peter D. Nagy. "Nucleolin/Nsr1p binds to the 3′ noncoding region of the tombusvirus RNA and inhibits replication." Virology 396, no. 1 (January 2010): 10–20. http://dx.doi.org/10.1016/j.virol.2009.10.007.

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Choi, Dan-Bee, Moo-Rim Park, Hak-Ryul Kim, Chang-Duk Jun, Hyeoung-Joon Kim, Hyeok Shim, Young-Dae Kim, et al. "Aberrant proteomic expression of NSRP70 and its clinical implications and connection to the transcriptional level in adult acute leukemia." Leukemia Research 38, no. 10 (October 2014): 1252–59. http://dx.doi.org/10.1016/j.leukres.2014.08.001.

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Azevedo, Cristina, and Adolfo Saiardi. "The new world of inorganic polyphosphates." Biochemical Society Transactions 44, no. 1 (February 9, 2016): 13–17. http://dx.doi.org/10.1042/bst20150210.

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Post-translational modifications (PTMs) add regulatory features to proteins that help establish the complex functional networks that make up higher organisms. Advances in analytical detection methods have led to the identification of more than 200 types of PTMs. However, some modifications are unstable under the present detection methods, anticipating the existence of further modifications and a much more complex map of PTMs. An example is the recently discovered protein modification polyphosphorylation. Polyphosphorylation is mediated by inorganic polyphosphate (polyP) and represents the covalent attachment of this linear polymer of orthophosphate to lysine residues in target proteins. This modification has eluded MS analysis as both polyP itself and the phosphoramidate bonds created upon its reaction with lysine residues are highly unstable in acidic conditions. Polyphosphorylation detection was only possible through extensive biochemical characterization. Two targets have been identified: nuclear signal recognition 1 (Nsr1) and its interacting partner, topoisomerase 1 (Top1). Polyphosphorylation occurs within a conserved N-terminal polyacidic serine (S) and lysine (K) rich (PASK) cluster. It negatively regulates Nsr1–Top1 interaction and impairs Top1 enzymatic activity, namely relaxing supercoiled DNA. Modulation of cellular levels of polyP regulates Top1 activity by modifying its polyphosphorylation status. Here we discuss the significance of the recently identified new role of inorganic polyP.

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McGrath, K. E., J. F. Smothers, C. A. Dadd, M. T. Madireddi, M. A. Gorovsky, and C. D. Allis. "An abundant nucleolar phosphoprotein is associated with ribosomal DNA in Tetrahymena macronuclei." Molecular Biology of the Cell 8, no. 1 (January 1997): 97–108. http://dx.doi.org/10.1091/mbc.8.1.97.

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An abundant 52-kDa phosphoprotein was identified and characterized from macronuclei of the ciliated protozoan Tetrahymena thermophila. Immunoblot analyses combined with light and electron microscopic immunocytochemistry demonstrate that this polypeptide, termed Nopp52, is enriched in the nucleoli of transcriptionally active macronuclei and missing altogether from transcriptionally inert micronuclei. The cDNA sequence encoding Nopp52 predicts a polypeptide whose amino-terminal half consists of multiple acidic/serine-rich regions alternating with basic/proline-rich regions. Multiple serines located in these acidic stretches lie within casein kinase II consensus motifs, and Nopp52 is an excellent substrate for casein kinase II in vitro. The carboxyl-terminal half of Nopp52 contains two RNA recognition motifs and an extreme carboxyl-terminal domain rich in glycine, arginine, and phenylalanine, motifs common in many RNA processing proteins. A similar combination and order of motifs is found in vertebrate nucleolin and yeast NSR1, suggesting that Nopp52 is a member of a family of related nucleolar proteins. NSR1 and nucleolin have been implicated in transcriptional regulation of rDNA and rRNA processing. Consistent with a role in ribosomal gene metabolism, rDNA and Nopp52 colocalize in situ, as well as by cross-linking and immunoprecipitation experiments, demonstrating an association between Nopp52 and rDNA in vivo.

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Edwards, Troy K., Ahamed Saleem, Jeffrey A. Shaman, Tracey Dennis, Claudia Gerigk, Elder Oliveros, Marc R. Gartenberg, and Eric H. Rubin. "Role for Nucleolin/Nsr1 in the Cellular Localization of Topoisomerase I." Journal of Biological Chemistry 275, no. 46 (August 30, 2000): 36181–88. http://dx.doi.org/10.1074/jbc.m006628200.

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