Journal articles on the topic 'Nox4 overexpression'
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Kim, Young-Mee, Seok-Jo Kim, Ryosuke Tatsunami, Hisao Yamamura, Tohru Fukai, and Masuko Ushio-Fukai. "ROS-induced ROS release orchestrated by Nox4, Nox2, and mitochondria in VEGF signaling and angiogenesis." American Journal of Physiology-Cell Physiology 312, no. 6 (June 1, 2017): C749—C764. http://dx.doi.org/10.1152/ajpcell.00346.2016.
Full textMoon, Joon Hwan, Tae Hoon Kim, Heung Man Lee, Seung Hoon Lee, Whan Choe, Ha Kyun Kim, Jung Hoon Lee, Kyoung Ho Oh, and Sang Hag Lee. "Overexpression of the Superoxide Anion and NADPH Oxidase Isoforms 1 and 4 (NOX1 and NOX4) in Allergic Nasal Mucosa." American Journal of Rhinology & Allergy 23, no. 4 (July 2009): 370–76. http://dx.doi.org/10.2500/ajra.2009.23.3340.
Full textNadworny, Alyson S., Mallik R. Guruju, Daniel Poor, Robert M. Doran, Ram V. Sharma, Michael I. Kotlikoff, and Robin L. Davisson. "Nox2 and Nox4 influence neonatal c-kit+ cardiac precursor cell status and differentiation." American Journal of Physiology-Heart and Circulatory Physiology 305, no. 6 (September 15, 2013): H829—H842. http://dx.doi.org/10.1152/ajpheart.00761.2012.
Full textHu, Fang, Meng Xue, Yang Li, Yi-Jie Jia, Zong-Ji Zheng, Yan-Lin Yang, Mei-Ping Guan, Liao Sun, and Yao-Ming Xue. "Early Growth Response 1 (Egr1) Is a Transcriptional Activator of NOX4 in Oxidative Stress of Diabetic Kidney Disease." Journal of Diabetes Research 2018 (2018): 1–10. http://dx.doi.org/10.1155/2018/3405695.
Full textGusan, Svetlana, and Madhu B. Anand-Srivastava. "cAMP attenuates the enhanced expression of Gi proteins and hyperproliferation of vascular smooth muscle cells from SHR: role of ROS and ROS-mediated signaling." American Journal of Physiology-Cell Physiology 304, no. 12 (June 15, 2013): C1198—C1209. http://dx.doi.org/10.1152/ajpcell.00269.2012.
Full textChen, Dan, Ying-Hao Zang, Yun Qiu, Feng Zhang, Ai-Dong Chen, Jue-Jin Wang, Qi Chen, Yue-Hua Li, Yu-Ming Kang, and Guo-Qing Zhu. "BCL6 Attenuates Proliferation and Oxidative Stress of Vascular Smooth Muscle Cells in Hypertension." Oxidative Medicine and Cellular Longevity 2019 (January 22, 2019): 1–9. http://dx.doi.org/10.1155/2019/5018410.
Full textNishimura, Ataru, Tetsuro Ago, Junya Kuroda, Koichi Arimura, Masaki Tachibana, Kuniyuki Nakamura, Yoshinobu Wakisaka, Junichi Sadoshima, Koji Iihara, and Takanari Kitazono. "Detrimental role of pericyte Nox4 in the acute phase of brain ischemia." Journal of Cerebral Blood Flow & Metabolism 36, no. 6 (October 13, 2015): 1143–54. http://dx.doi.org/10.1177/0271678x15606456.
Full textChen, Yen-Hao, Chih-Yen Chien, Fu-Min Fang, Tai-Lin Huang, Yan-Ye Su, Sheng-Dean Luo, Chao-Cheng Huang, Wei-Che Lin, and Shau-Hsuan Li. "Nox4 Overexpression as a Poor Prognostic Factor in Patients with Oral Tongue Squamous Cell Carcinoma Receiving Surgical Resection." Journal of Clinical Medicine 7, no. 12 (December 1, 2018): 497. http://dx.doi.org/10.3390/jcm7120497.
Full textWang, Xi-Ling, Li-Long Pan, Fen Long, Wei-Jun Wu, Di Yan, Peng Xu, Si-Yu Liu, et al. "Endogenous Hydrogen Sulfide Ameliorates NOX4 Induced Oxidative Stress in LPS-Stimulated Macrophages and Mice." Cellular Physiology and Biochemistry 47, no. 2 (2018): 458–74. http://dx.doi.org/10.1159/000489980.
Full textFang, Lijun, Wei Wang, Jiazheng Chen, Anju Zuo, Hongmei Gao, Tao Yan, Pengqi Wang, et al. "Osthole Attenuates Bleomycin-Induced Pulmonary Fibrosis by Modulating NADPH Oxidase 4-Derived Oxidative Stress in Mice." Oxidative Medicine and Cellular Longevity 2021 (September 4, 2021): 1–12. http://dx.doi.org/10.1155/2021/3309944.
Full textDong, Qingqing, Xiaohong Zhang, and Min Zhang. "Long Noncoding RNA-5657 Inhibits the Proliferation of Pancreatic Cells and Insulin Secretion in Gestational Diabetes by Inhibiting the NADPH Oxidase 4 (NOX4)." Journal of Biomaterials and Tissue Engineering 12, no. 9 (September 1, 2022): 1825–30. http://dx.doi.org/10.1166/jbt.2022.3113.
Full textMa, Jia, Qian Cai, Dandan Yang, Jiali Yang, Jing Xue, Miao Yu, Yingxue Liu, Fucheng Ma, Feng Li, and Xiaoming Liu. "A Positive Feed Forward Loop between Wnt/β-Catenin and NOX4 Promotes Silicon Dioxide-Induced Epithelial-Mesenchymal Transition of Lung Epithelial Cells." Oxidative Medicine and Cellular Longevity 2020 (December 8, 2020): 1–16. http://dx.doi.org/10.1155/2020/3404168.
Full textXu, Ning, Hao Meng, Tianyi Liu, Yingli Feng, Yuan Qi, and Honglei Wang. "TRPC1 Deficiency Exacerbates Cerebral Ischemia/Reperfusion-Induced Neurological Injury by Potentiating Nox4-Derived Reactive Oxygen Species Generation." Cellular Physiology and Biochemistry 51, no. 4 (2018): 1723–38. http://dx.doi.org/10.1159/000495676.
Full textSantana-Garrido, Álvaro, Claudia Reyes-Goya, Pablo Espinosa-Martín, Luis Sobrevia, Luis M. Beltrán, Carmen M. Vázquez, and Alfonso Mate. "Oxidative and Inflammatory Imbalance in Placenta and Kidney of sFlt1-Induced Early-Onset Preeclampsia Rat Model." Antioxidants 11, no. 8 (August 19, 2022): 1608. http://dx.doi.org/10.3390/antiox11081608.
Full textDiebold, Isabel, Andreas Petry, John Hess, and Agnes Görlach. "The NADPH Oxidase Subunit NOX4 Is a New Target Gene of the Hypoxia-inducible Factor-1." Molecular Biology of the Cell 21, no. 12 (June 15, 2010): 2087–96. http://dx.doi.org/10.1091/mbc.e09-12-1003.
Full textHaurani, Mounir J., M. Eugenia Cifuentes, Alexander D. Shepard, and Patrick J. Pagano. "Nox4 Oxidase Overexpression Specifically Decreases Endogenous Nox4 mRNA and Inhibits Angiotensin II–Induced Adventitial Myofibroblast Migration." Hypertension 52, no. 1 (July 2008): 143–49. http://dx.doi.org/10.1161/hypertensionaha.107.101667.
Full textLeclerc, Joan, Debeissat Christelle, Socco-Lucca Marion, Ducrocq Elfi, Gouilleux Fabrice, Stasia Marie José, and Olivier Herault. "Influence of NADPH Oxidase Activity On the Reactive Oxygen Species Level in Human Leukemic Cells." Blood 120, no. 21 (November 16, 2012): 4801. http://dx.doi.org/10.1182/blood.v120.21.4801.4801.
Full textStas, Sameer, Adam Whaley-Connell, Javad Habibi, Lama Appesh, Melvin R. Hayden, Poorna R. Karuparthi, Mahnaz Qazi, et al. "Mineralocorticoid Receptor Blockade Attenuates Chronic Overexpression of the Renin-Angiotensin-Aldosterone System Stimulation of Reduced Nicotinamide Adenine Dinucleotide Phosphate Oxidase and Cardiac Remodeling." Endocrinology 148, no. 8 (August 1, 2007): 3773–80. http://dx.doi.org/10.1210/en.2006-1691.
Full textLi, Jingming, Joshua J. Wang, and Sarah X. Zhang. "NADPH Oxidase 4-Derived H2O2Promotes Aberrant Retinal Neovascularization via Activation of VEGF Receptor 2 Pathway in Oxygen-Induced Retinopathy." Journal of Diabetes Research 2015 (2015): 1–13. http://dx.doi.org/10.1155/2015/963289.
Full textQi, Jie, Xue Luo, Zhichao Ma, Bo Zhang, Shuyan Li, Xuyang Duan, Bo Yang, and Jun Zhang. "Swimming Exercise Protects against Insulin Resistance via Regulating Oxidative Stress through Nox4 and AKT Signaling in High-Fat Diet-Fed Mice." Journal of Diabetes Research 2020 (January 21, 2020): 1–9. http://dx.doi.org/10.1155/2020/2521590.
Full textVelimirović, Milica, Gordana Jevtić Dožudić, Vesna Selaković, Tihomir Stojković, Nela Puškaš, Ivan Zaletel, Milica Živković, et al. "Effects of Vitamin D3 on the NADPH Oxidase and Matrix Metalloproteinase 9 in an Animal Model of Global Cerebral Ischemia." Oxidative Medicine and Cellular Longevity 2018 (2018): 1–14. http://dx.doi.org/10.1155/2018/3273654.
Full textXiao, Qingzhong, Zhenling Luo, Anna Elena Pepe, Andriani Margariti, Lingfang Zeng, and Qingbo Xu. "Embryonic stem cell differentiation into smooth muscle cells is mediated by Nox4-produced H2O2." American Journal of Physiology-Cell Physiology 296, no. 4 (April 2009): C711—C723. http://dx.doi.org/10.1152/ajpcell.00442.2008.
Full textBalzamino, Bijorn Omar, Lucia Dinice, Andrea Cacciamani, Agnese Re, Fabio Scarinci, Luca Bruno, Pamela Cosimi, and Alessandra Micera. "Short-Term In Vitro ROS Detection and Oxidative Stress Regulators in Epiretinal Membranes and Vitreous from Idiopathic Vitreoretinal Diseases." BioMed Research International 2022 (December 16, 2022): 1–12. http://dx.doi.org/10.1155/2022/7497816.
Full textLu, Xianghuai, Tamara C. Murphy, Mark S. Nanes, and C. Michael Hart. "PPARγ regulates hypoxia-induced Nox4 expression in human pulmonary artery smooth muscle cells through NF-κB." American Journal of Physiology-Lung Cellular and Molecular Physiology 299, no. 4 (October 2010): L559—L566. http://dx.doi.org/10.1152/ajplung.00090.2010.
Full textHuang, Jianhua, Li Li, Weifeng Yuan, Linxin Zheng, Zhenhui Guo, and Wenjie Huang. "NEMO-Binding Domain Peptide Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting the NF-κB Signaling Pathway." Mediators of Inflammation 2016 (2016): 1–11. http://dx.doi.org/10.1155/2016/7349603.
Full textDatla, Srinivasa Raju, Daniel J. McGrail, Sasa Vukelic, Lauren P. Huff, Alicia N. Lyle, Lily Pounkova, Minyoung Lee, et al. "Poldip2 controls vascular smooth muscle cell migration by regulating focal adhesion turnover and force polarization." American Journal of Physiology-Heart and Circulatory Physiology 307, no. 7 (October 1, 2014): H945—H957. http://dx.doi.org/10.1152/ajpheart.00918.2013.
Full textSu, Xiangsheng, Yihang Yang, Changfa Guo, Rui Zhang, Shicheng Sun, Yanjun Wang, Qiujiang Qiao, Yibing Fu, and Qi Pang. "NOX4-Derived ROS Mediates TGF-β1-Induced Metabolic Reprogramming during Epithelial-Mesenchymal Transition through the PI3K/AKT/HIF-1α Pathway in Glioblastoma." Oxidative Medicine and Cellular Longevity 2021 (June 27, 2021): 1–30. http://dx.doi.org/10.1155/2021/5549047.
Full textChai, DongDong, Lei Zhang, SiWei Xi, YanYong Cheng, Hong Jiang, and Rong Hu. "Nrf2 Activation Induced by Sirt1 Ameliorates Acute Lung Injury After Intestinal Ischemia/Reperfusion Through NOX4-Mediated Gene Regulation." Cellular Physiology and Biochemistry 46, no. 2 (2018): 781–92. http://dx.doi.org/10.1159/000488736.
Full textHuang, Yongpan, Jiayu Tang, Xiaojuan Li, Xian Long, Yansong Huang, and Xi Zhang. "miR-92b-3p Exerts Neuroprotective Effects on Ischemia/Reperfusion-Induced Cerebral Injury via Targeting NOX4 in a Rat Model." Oxidative Medicine and Cellular Longevity 2022 (March 30, 2022): 1–16. http://dx.doi.org/10.1155/2022/3494262.
Full textGao, Jie, Ying Meng, Xin Ge, Chen-Xing Hou, Qing-Hai Zhu, Yi-Zhou Wang, Li-Fan Sun, et al. "SATB2 overexpression promotes oral squamous cell carcinoma progression by up-regulating NOX4." Cellular Signalling 82 (June 2021): 109968. http://dx.doi.org/10.1016/j.cellsig.2021.109968.
Full textMahadev, Kalyankar, Hiroyuki Motoshima, Xiangdong Wu, Jean Marie Ruddy, Rebecca S. Arnold, Guangjie Cheng, J. David Lambeth, and Barry J. Goldstein. "The NAD(P)H Oxidase Homolog Nox4 Modulates Insulin-Stimulated Generation of H2O2 and Plays an Integral Role in Insulin Signal Transduction." Molecular and Cellular Biology 24, no. 5 (March 1, 2004): 1844–54. http://dx.doi.org/10.1128/mcb.24.5.1844-1854.2004.
Full textZhang, M., Y. H. Looi, A. C. Brewer, and A. M. Shah. "010 Cardiomyocyte-specific overexpression of Nox4 attenuates adverse cardiac remodelling after myocardial infarction." Heart 96, no. 4 (February 1, 2010): e3-e4. http://dx.doi.org/10.1136/hrt.2009.191049j.
Full textGoettsch, Claudia, Winfried Goettsch, Gregor Muller, Jochen Seebach, Hans-Joachim Schnittler, and Henning Morawietz. "Nox4 overexpression activates reactive oxygen species and p38 MAPK in human endothelial cells." Biochemical and Biophysical Research Communications 380, no. 2 (March 2009): 355–60. http://dx.doi.org/10.1016/j.bbrc.2009.01.107.
Full textWang, Jinju, Shuzhen Chen, and Ji Bihl. "Exosome-Mediated Transfer of ACE2 (Angiotensin-Converting Enzyme 2) from Endothelial Progenitor Cells Promotes Survival and Function of Endothelial Cell." Oxidative Medicine and Cellular Longevity 2020 (January 20, 2020): 1–11. http://dx.doi.org/10.1155/2020/4213541.
Full textCraps, Julie, Virginie Joris, Lelio Baldeschi, Chantal Daumerie, Alessandra Camboni, Antoine Buemi, Benoit Lengelé, et al. "miR-199a Downregulation as a Driver of the NOX4/HIF-1α/VEGF-A Pathway in Thyroid and Orbital Adipose Tissues from Graves′ Patients." International Journal of Molecular Sciences 23, no. 1 (December 23, 2021): 153. http://dx.doi.org/10.3390/ijms23010153.
Full textLin, Xiao-Lu, Li Yang, Seng-Wang Fu, Wen-Feng Lin, Yun-Jie Gao, Hao-Yan Chen, and Zhi-Zheng Ge. "Overexpression of NOX4 predicts poor prognosis and promotes tumor progression in human colorectal cancer." Oncotarget 8, no. 20 (April 4, 2017): 33586–600. http://dx.doi.org/10.18632/oncotarget.16829.
Full textXue, Jiahong, Jiali Fan, Yuan Li, Wenhuan Wu, Qing Yan, and Qiangsun Zheng. "ABCG1 Attenuates Oxidative Stress Induced by H2O2 through the Inhibition of NADPH Oxidase and the Upregulation of Nrf2-Mediated Antioxidant Defense in Endothelial Cells." Analytical Cellular Pathology 2020 (December 3, 2020): 1–11. http://dx.doi.org/10.1155/2020/2095645.
Full textGomes, Pedro, Sónia Simão, Elisabete Silva, Vanda Pinto, João S. Amaral, Joana Afonso, Maria Paula Serrão, Maria João Pinho, and Patrício Soares-da-Silva. "Aging increases Oxidative Stress and Renal Expression of Oxidant and Antioxidant Enzymes that Are Associated with an Increased Trend in Systolic Blood Pressure." Oxidative Medicine and Cellular Longevity 2, no. 3 (2009): 138–45. http://dx.doi.org/10.4161/oxim.2.3.8819.
Full textKim, Ha-Rim, and Seon-Young Kim. "Perilla frutescens Sprout Extract Protect Renal Mesangial Cell Dysfunction against High Glucose by Modulating AMPK and NADPH Oxidase Signaling." Nutrients 11, no. 2 (February 8, 2019): 356. http://dx.doi.org/10.3390/nu11020356.
Full textCao, Xinran, Shiran Yu, Yuanyuan Wang, Min Yang, Jie Xiong, Haitao Yuan, and Bo Dong. "Effects of the (Pro)renin Receptor on Cardiac Remodeling and Function in a Rat Alcoholic Cardiomyopathy Model via the PRR-ERK1/2-NOX4 Pathway." Oxidative Medicine and Cellular Longevity 2019 (March 13, 2019): 1–13. http://dx.doi.org/10.1155/2019/4546975.
Full textHuff, Lauren Parker, Daniel Seicho Kikuchi, Elizabeth Faidley, Steven J. Forrester, Michelle Z. Tsai, Bernard Lassègue, and Kathy K. Griendling. "Polymerase-δ-interacting protein 2 activates the RhoGEF epithelial cell transforming sequence 2 in vascular smooth muscle cells." American Journal of Physiology-Cell Physiology 316, no. 5 (May 1, 2019): C621—C631. http://dx.doi.org/10.1152/ajpcell.00208.2018.
Full textChen, Yen-Hao, Hung-I. Lu, Chien-Ming Lo, Chang-Chun Hsiao, and Shau-Hsuan Li. "NOX4 overexpression is a poor prognostic factor in patients undergoing curative esophagectomy for esophageal squamous cell carcinoma." Surgery 167, no. 3 (March 2020): 620–27. http://dx.doi.org/10.1016/j.surg.2019.11.017.
Full textFriis, Martin Barfred, Katrine Gribel Vorum, and Ian Henry Lambert. "Volume-sensitive NADPH oxidase activity and taurine efflux in NIH3T3 mouse fibroblasts." American Journal of Physiology-Cell Physiology 294, no. 6 (June 2008): C1552—C1565. http://dx.doi.org/10.1152/ajpcell.00571.2007.
Full textWang, Dong, Shi-Ping Li, Jin-Sheng Fu, Sheng Zhang, Lin Bai, and Li Guo. "Resveratrol defends blood-brain barrier integrity in experimental autoimmune encephalomyelitis mice." Journal of Neurophysiology 116, no. 5 (November 1, 2016): 2173–79. http://dx.doi.org/10.1152/jn.00510.2016.
Full textKim, Hyun Jik, Chang-Hoon Kim, Ji-Hwan Ryu, Jung Hee Joo, Sang-Nam Lee, Min-Ji Kim, Jeung-Gweon Lee, Yun Soo Bae, and Joo-Heon Yoon. "Crosstalk between platelet-derived growth factor-induced Nox4 activation and MUC8 gene overexpression in human airway epithelial cells." Free Radical Biology and Medicine 50, no. 9 (May 2011): 1039–52. http://dx.doi.org/10.1016/j.freeradbiomed.2011.01.014.
Full textAlves, Renata, Camila Liyoko Suehiro, Flavia Garcia de Oliveira, Eliete Dalla Corte Frantz, Renata Frauches de Medeiros, Rodolfo de Paula Vieira, Milton de Arruda Martins, Chin Jia Lin, Antonio Claudio Lucas da Nobrega, and Alessandra Choqueta de Toledo-Arruda. "Aerobic exercise modulates cardiac NAD(P)H oxidase and the NRF2/KEAP1 pathway in a mouse model of chronic fructose consumption." Journal of Applied Physiology 128, no. 1 (January 1, 2020): 59–69. http://dx.doi.org/10.1152/japplphysiol.00201.2019.
Full textDou, Fangfang, Beiling Wu, Lin Sun, Jiulin Chen, Te Liu, Zhihua Yu, and Chuan Chen. "Identification of a novel regulatory pathway for PPARα by RNA-seq characterization of the endothelial cell lipid peroxidative injury transcriptome." Open Biology 9, no. 12 (December 2019): 190141. http://dx.doi.org/10.1098/rsob.190141.
Full textBai, Yangqiu, Jinying Liu, Xiaoke Jiang, Xiuling Li, Bingyong Zhang, and Xiaoying Luo. "Nucleophagic Degradation of Progerin Ameliorates Defenestration in Liver Sinusoidal Endothelium Due to SIRT1-Mediated Deacetylation of Nuclear LC3." Cells 11, no. 23 (December 3, 2022): 3918. http://dx.doi.org/10.3390/cells11233918.
Full textAdesina, Sherry E., Brandy E. Wade, Kaiser M. Bijli, Bum-Yong Kang, Clintoria R. Williams, Jing Ma, Young-Mi Go, C. Michael Hart, and Roy L. Sutliff. "Hypoxia inhibits expression and function of mitochondrial thioredoxin 2 to promote pulmonary hypertension." American Journal of Physiology-Lung Cellular and Molecular Physiology 312, no. 5 (May 1, 2017): L599—L608. http://dx.doi.org/10.1152/ajplung.00258.2016.
Full textGu, Yanting, Yuewen Gong, Haojun Zhang, Xi Dong, Tingting Zhao, Frank J. Burczynski, Guqi Wang, et al. "Regulation of transforming growth factor beta 1 gene expression by dihydropteridine reductase in kidney 293T cells." Biochemistry and Cell Biology 91, no. 3 (June 2013): 187–93. http://dx.doi.org/10.1139/bcb-2012-0087.
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