Academic literature on the topic 'Novel Human Protein Family'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Novel Human Protein Family.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Journal articles on the topic "Novel Human Protein Family"
Elbadawy, Mohamed, Tatsuya Usui, Hideyuki Yamawaki, and Kazuaki Sasaki. "Novel Functions of Death-Associated Protein Kinases through Mitogen-Activated Protein Kinase-Related Signals." International Journal of Molecular Sciences 19, no. 10 (October 4, 2018): 3031. http://dx.doi.org/10.3390/ijms19103031.
Full textDavis, Beckley, Aaron Tocker, Suzanna Talento, and Kimberly Jacob. "Identification of a novel protein protein interaction pathway with NLRC3 (INM2P.359)." Journal of Immunology 194, no. 1_Supplement (May 1, 2015): 126.12. http://dx.doi.org/10.4049/jimmunol.194.supp.126.12.
Full textGuignard, F., J. Mauel, and M. Markert. "Identification and characterization of a novel human neutrophil protein related to the S100 family." Biochemical Journal 309, no. 2 (July 15, 1995): 395–401. http://dx.doi.org/10.1042/bj3090395.
Full textSingh, Mahendra K., Disha Dadke, Emmanuelle Nicolas, Ilya G. Serebriiskii, Sinoula Apostolou, Adrian Canutescu, Brian L. Egleston, and Erica A. Golemis. "A Novel Cas Family Member, HEPL, Regulates FAK and Cell Spreading." Molecular Biology of the Cell 19, no. 4 (April 2008): 1627–36. http://dx.doi.org/10.1091/mbc.e07-09-0953.
Full textLi, Xin, Lei Chen, Chaoneng Ji, Bing Liu, Jiefeng Gu, Jian Xu, Xianqiong Zou, Shaohua Gu, and Yumin Mao. "Isolation and expression pattern of RGS21 gene, a novel RGS member." Acta Biochimica Polonica 52, no. 4 (September 8, 2005): 943–46. http://dx.doi.org/10.18388/abp.2005_3412.
Full textRakowicz-Szulczynska, Ewa M., David G. McIntosh, Peter Morris, and McClure Smith. "Novel Family of Gynecologic Cancer Antigens Detected by Anti-HIV Antibody." Infectious Diseases in Obstetrics and Gynecology 2, no. 4 (1994): 171–78. http://dx.doi.org/10.1155/s1064744994000608.
Full textSuk, Kyoungho, Sunshin Kim, Yun-Hee Kim, Seung-Hoon Oh, Moon-Kyu Lee, Kwang-Won Kim, Hee-Dai Kim, Yeon-Soo Seo, and Myung-Shik Lee. "Identification of a novel human member of the DEAD box protein family." Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1501, no. 1 (April 2000): 63–69. http://dx.doi.org/10.1016/s0925-4439(00)00010-7.
Full textLev, Sima, John Hernandez, Ricardo Martinez, Alon Chen, Greg Plowman, and Joseph Schlessinger. "Identification of a Novel Family of Targets of PYK2 Related to Drosophila Retinal Degeneration B (rdgB) Protein." Molecular and Cellular Biology 19, no. 3 (March 1, 1999): 2278–88. http://dx.doi.org/10.1128/mcb.19.3.2278.
Full textSellers, Robert A., David L. Robertson, and May Tassabehji. "Ancestry of the AUTS2 family–A novel group of polycomb-complex proteins involved in human neurological disease." PLOS ONE 15, no. 12 (December 11, 2020): e0232101. http://dx.doi.org/10.1371/journal.pone.0232101.
Full textSkeiky, Y. A., D. R. Benson, J. A. Guderian, P. R. Sleath, M. Parsons, and S. G. Reed. "Trypanosoma cruzi acidic ribosomal P protein gene family. Novel P proteins encoding unusual cross-reactive epitopes." Journal of Immunology 151, no. 10 (November 15, 1993): 5504–15. http://dx.doi.org/10.4049/jimmunol.151.10.5504.
Full textDissertations / Theses on the topic "Novel Human Protein Family"
Cloonan, Nicole, and N/A. "Sin1 and Sin1 Isoforms: An Investigation into the Biological Significance of a Novel Human Protein Family." Griffith University. School of Biomolecular and Biomedical Science, 2006. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20071102.150237.
Full textCloonan, Nicole. "Sin1 and Sin1 Isoforms: An Investigation into the Biological Significance of a Novel Human Protein Family." Thesis, Griffith University, 2006. http://hdl.handle.net/10072/367210.
Full textThesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Biomolecular and Biomedical Sciences
Full Text
Nilsson, Jonas. "The LRIG-family : identification of novel regulators of ErbB signaling with clinical implications in astrocytoma /." Doctoral thesis, Umeå : Department of Radiation Sciences, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-783.
Full textBartee, Eric Carter. "Discovery and characterization of a novel family of human ubiquitin ligases termed Membrane Associated RING-CH (MARCH) proteins." Oregon Health & Science University, 2007. http://content.ohsu.edu/u?/etd,629.
Full textMolecular Microbiology and Immunology
Both poxviruses and γ2-herpesviruses share the K3-family of viral immune evasion proteins. These proteins are characterized by an amino-terminal RING-CH domain followed by two transmembrane domains. We analyzed several human homologues of the K3-family termed membrane-associated RING-CH (MARCH) proteins. All MARCH proteins localized to subcellular membranes while several reduced surface levels of known K3-family substrates. Thus, MARCH proteins appear to be structurally and functionally homologous to viral K3 proteins. One of the major challenges in determining the function of this family is the identification of their physiological substrates. To overcome this we created a quantitative proteomics approach which can be used to identify novel substrates for both the K3- and MARCH-families. Using stable isotope labeling by amino acids in cell culture, we compared the proteome of plasma membrane, golgi, and endoplasmic reticulum membranes in the presence and absence of K5 and MARCH-VIII. Quantitative mass spectrometric protein identification from these fractions revealed that CD316 (bone marrow stromal antigen 2), CD166 (activated leukocyte cell adhesion molecule) and syntaxin-4 were consistently underrepresented in the plasma membrane of K5 expressing cells, while CD44, CD81 (TAPA-1) and B-cell receptor-associated protein 31kDa (Bap31) were consistently underrepresented in the plasma membrane of MARCH-VIII expressing cells. Furthermore, downregulation of each of these proteins was independently confirmed. Our results both identify and characterize a novel family of human ubiquitin ligase enzymes and elucidate a novel technique which can analyze this family and be easily adapted to the analysis of other cellular enzymes viral immune modulators.
Iwai, Akio. "Siah-1L, a novel transcript variant belonging to the human Siah family of proteins, regulates β-catenin activity in a p53-dependent manner." Kyoto University, 2005. http://hdl.handle.net/2433/144711.
Full textRuane, Peter Thomas. "Functional characterisation of human EB protein family member EB2." Thesis, University of Leeds, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.550859.
Full textTemprano, López Ana. "The lipin protein family in human adipocytes: lipid metabolism and obesity." Doctoral thesis, Universitat Rovira i Virgili, 2016. http://hdl.handle.net/10803/398025.
Full textLas lipinas son una familia de fosfatasas de fosfatidato (PAP1) dependientes de Mg2+ evolutivamente conservadas, que generan diacilglicerol para la síntesis de fosfolípidos y triacilglicerol. En mamíferos, la familia consiste en lipina-1, lipina-2, y lipina-3. Mientras en ratones la mutación del gen Lpin1 causa lipodistrofia, las mutaciones deletéreas en el gen LPIN1 en humanos no afectan a la distribución de grasa. Sin embargo, los individuos con diabetes tipo 2 manifiestan niveles reducidos de expresión de LPIN1 y de actividad PAP1. En esta tesis doctoral se estudia la función de las lipinas en el tejido adiposo humano, la adipogénesis y la lipólisis. Descubrimos que la expresión génica y proteica de las lipinas está alterada en el tejido adiposo de individuos con diabetes tipo 2. La depleción de cada miembro de las lipinas en la línea celular humana de preadipocitos del síndrome Simpson–Golabi–Behmel (SGBS), mostró que, a pesar de que los tres miembros tienen un papel en la adipogénesis temprana, los adipocitos deplecionados de lipinas se diferencian y acumulan lípidos neutros, llevándonos a la hipótesis de la existencia de vías alternativas para la síntesis de triacilglicerol en adipocitos humanos cuando la expresión de las lipinas es reprimida. Las lipinas también intervienen en el reciclaje de los ácidos grasos liberados por la vía lipolítica. Tras la inducción de la lipólisis, las lipinas son defosforiladas y se desplazan a la membrana del retículo endoplásmico, donde ejercen su función. Esta activación es inducida por los ácidos grasos liberados, y revertida con albúmina o triacsin C. La depleción de cada lipina en adipocitos SGBS y posterior inducción de la lipólisis, demuestra su papel en el metabolismo de lípidos neutros. En resumen, las lipinas parecen no tener un papel indispensable en la adipogénesis humana pero sí comprometer el reciclaje de ácidos grasos, importante para la homeostasis lipídica.
Lipins are evolutionarily conserved Mg2+-dependent phosphatidate phosphatases (PAP1) that generate diacylglycerol for phospholipid and triacylglycerol synthesis. In mammals the Lipin family consists of lipin-1, lipin-2 and lipin-3. Whereas mutations in the Lpin1 gene cause lipodystrophy in mouse models, LPIN1 deleterious mutations in humans do not affect fat distribution. However, reduced LPIN1 expression and PAP1 activity have been described in participants with type 2 diabetes. In this doctoral thesis we investigate the roles of all lipin family members in human adipose tissue, adipogenesis and lipolysis. We found that adipose tissue gene and protein expression of the lipin family is altered in type 2 diabetes. Depletion of every lipin family member in a human Simpson–Golabi–Behmel syndrome (SGBS) pre-adipocyte cell line showed that even though all members alter early stages of adipogenesis, lipin-silenced cells differentiate and accumulate neutral lipids, pointing to the hypothesis of alternative pathways for triacylglycerol synthesis under repression of lipin expression. Lipins also have a role in the recycling of the fatty acids released by the lipolytic pathway. They become dephosphorylated upon lipolytic induction, and translocate to their active site, the endoplasmic reticulum membrane. This activation is induced by fatty acids and reversed with albumin or triacsin C. Depletion of every lipin member and subsequently stimulation of lipolysis in SGBS adipocytes revealed a role for lipins in neutral lipid metabolism. Overall, our data support that lipins may not have an indispensable role in adipogenesis, but their depletion compromise fatty acid recycling and lipid homeostasis.
Chan, Che-man, and 陳志敏. "Functional study of spike protein of a novel human coronavirus HKU1." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B41896932.
Full textChan, Che-man. "Functional study of spike protein of a novel human coronavirus HKU1." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B41896932.
Full textRhyner, Johannes A. "The human calmodulin gene family and characterization of the calmodulin-like protein /." [S.l.] : [s.n.], 1994. http://e-collection.ethbib.ethz.ch/show?type=diss&nr=10508.
Full textBooks on the topic "Novel Human Protein Family"
Sawzdargo, Marek. Discovery of novel G protein-coupled receptor genes including human GALR3 receptor gene. Ottawa: National Library of Canada, 1999.
Find full textThe human bobby: A novel. New York, NY: Simon & Schuster, 2010.
Find full textDocherty, John Martin. The cloning and characterization of three novel human genes encoding G protein-coupled receptors. Ottawa: National Library of Canada, 1994.
Find full textBorchert, Monika. Characterization of p34, a human collagen-binding membrane protein in the annexin family. München: H. Gertner, 1990.
Find full textBoleto: A novel. Minneapolis, Minn: Graywolf Press, 2012.
Find full textCastillo, Ana. Guardians: A novel. New York: Random House Trade Paperbacks, 2008.
Find full textThe baby trail: A novel. New York: Atria Books, 2005.
Find full textPerfect life: A novel. New York: W.W. Norton & Co., 2009.
Find full textPicoult, Jodi. Sing you home: A novel. New York: Pocket Books, 2014.
Find full textMaitland, Sara. Daughter of Jerusalem: A novel. New York: H. Holt, 1995.
Find full textBook chapters on the topic "Novel Human Protein Family"
Hilt, Dana C., and Douglas Kligman. "The S-100 Protein Family: A Biochemical and Functional Overview." In Novel Calcium-Binding Proteins, 65–103. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76150-8_6.
Full textSatpute, Babasaheb S., and Raghav Yadav. "Recognition of Protein Family Using a Novel Classification System." In Communications in Computer and Information Science, 354–61. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-1423-0_37.
Full textKrishna, Neel K., and Kenji M. Cunnion. "Human Astrovirus Coat Protein: A Novel C1 Inhibitor." In Advances in Experimental Medicine and Biology, 228–42. New York, NY: Springer US, 2008. http://dx.doi.org/10.1007/978-0-387-78952-1_17.
Full textMatsuda, Y., A. Tsuji, H. Nagamume, T. Akamatsu, C. Hine, K. Muramatsu, K. Mori, Y. Tamai, and K. Yonemoto. "Novel Members of Mammalian Kexin Family Proteases, Pace 4C, Pace 4D, PC 7A and PC 7B." In Intracellular Protein Catabolism, 63–71. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4613-0335-0_7.
Full textLongbottom, David, and Veronica van Heyningen. "The Calgranulins, Members of the S-100 Protein Family: Structural Features, Expression, and Possible Function." In Novel Calcium-Binding Proteins, 191–223. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76150-8_12.
Full textHwa, Kuo-yuan, Wan-Man Lin, Chueh-Pai Lee, and Mei-Yu Chen. "Knowledge Management on the Novel LAGE-Like GlcNAc-Transferase Protein Family." In Bio-Science and Bio-Technology, 141–45. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-10616-3_19.
Full textIzzo, P., P. Costanzo, A. Lupo, and F. Salvatore. "NOVEL ASPECTS OF THE HUMAN ALDOLASE GENE FAMILY AND ITS EXPRESSION IN TUMOR CELLS." In Human Tumor Markers, edited by F. Cimino, G. D. Birkmayer, J. V. Klavins, E. Pimentel, and F. Salvatore, 889–98. Berlin, Boston: De Gruyter, 1987. http://dx.doi.org/10.1515/9783110846515-064.
Full textDoulami, Christiana, Uday Kishore, Robert B. Sim, and Wilhelm Schwaeble. "Mannose-Binding Lectin in Human Health and Disease." In The Collectin Protein Family and Its Multiple Biological Activities, 17–47. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-67048-1_2.
Full textBartalena, Luigi, Settimio Grimaldi, and Jacob Robbins. "Human Hepatoma (Hep G2) Cells Secrete a Novel T4-Binding Protein (27 K Protein)." In Frontiers in Thyroidology, 477–80. Boston, MA: Springer US, 1986. http://dx.doi.org/10.1007/978-1-4684-5260-0_84.
Full textGerke, Volker. "p11, A Member of the S-100 Protein Family, is Associated with the Tyrosine Kinase Substrate p36 (Annexin II)." In Novel Calcium-Binding Proteins, 139–55. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76150-8_9.
Full textConference papers on the topic "Novel Human Protein Family"
Jovanović-Šanta, Suzana S., Aleksandar M. Oklješa, Antos B. Sachanka, Yaraslau U. Dzichenka, and Sergei A. Usanov. "17-SUBSTITUTED STEROIDAL TETRAZOLES – NOVEL LIGANDS FOR HUMAN STEROID-CONVERTING CYP ENZYMES." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac, 2021. http://dx.doi.org/10.46793/iccbi21.336js.
Full textFujikawa, K., T. Funakoshi, R. L. Heimark, and J. F. Tait. "HUMAN PLACENTAL ANTICOAGULANT PROTEIN." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642949.
Full textTokunaga, F., T. Miyata, T. Nakamura, T. Morita, and S. Iwanaga. "LIPOPOLYSACCHARIDE-SENSITIVE SERINE-PROTEASE ZYMOGEN (FACTOR C) OF LIMULUS HEMOCYTES: IDENTIFICATION AND ALIGNMENT OF PROTEOLYTIC FRAGMENTS PRODUCED DURING THE ACTIVATION SHOW THAT IT IS A NOVEL TYPE OF SERINE-PROTEASE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644609.
Full textWasi, S., P. Alles, D. Gauthier, U. Bhargava, J. Farsi, J. E. Aubin, and J. Sodeki. "STUDIES ON SMALL MOLECULAR WEIGHT ADHESION PROTEINS (SAPs) FROM CONNECTIVE TISSUES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643556.
Full textMaheshwari, Reeti, Melissa Schluter, Danielle Pepin, and Joseph Hwang. "Abstract 4319: Analysis of Bcl-2 family members and protein-protein interactions using novel multiplex immunoassays." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-4319.
Full textGu, Hong, and Junzhe Cao. "A novel integrated method for human multiplex protein subcellular localization prediction." In 2013 IEEE International Conference on Big Data. IEEE, 2013. http://dx.doi.org/10.1109/bigdata.2013.6691734.
Full textYazdani, Mehrdad, Bryn C. Taylor, Justine W. Debelius, Weizhong Li, Rob Knight, and Larry Smarr. "Using machine learning to identify major shifts in human gut microbiome protein family abundance in disease." In 2016 IEEE International Conference on Big Data (Big Data). IEEE, 2016. http://dx.doi.org/10.1109/bigdata.2016.7840731.
Full textSeaman, Marc E., and Kimberly A. Kelly. "Abstract 3891: Hornerin: a novel, non-VEGF mediated human tumor angiogenic protein." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-3891.
Full textWang, Jing, Xuezhi Bi, and Shang Li. "Abstract 3469: Identification of novel human telomerase associated protein by mass spectrometry." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-3469.
Full textDejana, E., F. Breviario, F. Bussolino, L. Mussoni, and A. Mantovani. "PLEIOTROPIC EFFECT OF INTERLEUKIN-1 ON ENDOTHELIAL CELLS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643984.
Full textReports on the topic "Novel Human Protein Family"
Manning, Michael. Engineering a Cytolytic Human Protein into a Novel Prostate Cancer Protoxin. Fort Belvoir, VA: Defense Technical Information Center, March 2011. http://dx.doi.org/10.21236/ada600512.
Full textManning, Michael L. Engineering a Cytolytic Human Protein Into a Novel Prostate Cancer Protoxin. Fort Belvoir, VA: Defense Technical Information Center, March 2010. http://dx.doi.org/10.21236/ada603042.
Full textRichards, Talmesha. Polyamine Analogues as Novel Anti-HER Family Agents in Human Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, September 2008. http://dx.doi.org/10.21236/ada513832.
Full textRichards, Talmesha. Polyamine Analogues as Novel Anti-HER Family Agents in Human Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, September 2007. http://dx.doi.org/10.21236/ada477006.
Full textBarakat, Dr Shima, Dr Samuel Short, Dr Bernhard Strauss, and Dr Pantea Lotfian. https://www.food.gov.uk/research/research-projects/alternative-proteins-for-human-consumption. Food Standards Agency, June 2022. http://dx.doi.org/10.46756/sci.fsa.wdu243.
Full textHeitman, Joseph. Novel Gbeta Mimic Kelch Proteins (Gpb1 and Gpb2 Connect G-Protein Signaling to Ras via Yeast Neurofibromin Homologs Ira1 and Ira2: A Model for Human NF1. Fort Belvoir, VA: Defense Technical Information Center, March 2008. http://dx.doi.org/10.21236/ada483900.
Full textHeitman, Joseph, and Toshiaki Harashima. Novel Gbeta Mimic Kelch Proteins (Gpb1 and Gpb2 Connect G-Protein Signaling to Ras via Yeast Neurofibromin Homologs Ira1 and Ira2. A Model for Human NF1. Fort Belvoir, VA: Defense Technical Information Center, March 2007. http://dx.doi.org/10.21236/ada479028.
Full textHeitman, Joseph, and Toshiaki Harashima. Novel Gbeta Mimic Kelch Proteins Gpb1 and Gpb2 Connect G-Protein Signaling to Ras Via Yeast Neurofibromin Homologs Ira 1 and Ira 2: A Model for Human NF1. Fort Belvoir, VA: Defense Technical Information Center, March 2005. http://dx.doi.org/10.21236/ada446943.
Full textHeitman, Joseph. Novel Gbeta Mimic Kelch Proteins Gpb1 and Gpb2 Connect G-Protein Signaling to Ras via Yeast Neurofibromin Homologs Ira 1 and Ira 2: A Model for Human NF1. Fort Belvoir, VA: Defense Technical Information Center, March 2006. http://dx.doi.org/10.21236/ada469875.
Full textDolja, Valerian V., Amit Gal-On, and Victor Gaba. Suppression of Potyvirus Infection by a Closterovirus Protein. United States Department of Agriculture, March 2002. http://dx.doi.org/10.32747/2002.7580682.bard.
Full text