Journal articles on the topic 'Novel CRC therapies'
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Krauss, John, and Christine Veenstra. "Emerging Systemic Therapies for Colorectal Cancer." Clinics in Colon and Rectal Surgery 31, no. 03 (April 1, 2018): 179–91. http://dx.doi.org/10.1055/s-0037-1602238.
Full textTorres Adorno, Angie M., Julie Fong, Jeff Grein, Wendy Blumenschein, Danye Cheng, Katherine Porth, Peng Yang, Jennifer Yearley, Amy Beebe, and Barbara Joyce-Shaikh. "Development of a Humanized 3D Tumor Spheroid Models and Discovery of Effective Immunotherapy Strategies Against Resistant Microsatellite Stable Colorectal Cancers." Journal of Immunology 204, no. 1_Supplement (May 1, 2020): 241.9. http://dx.doi.org/10.4049/jimmunol.204.supp.241.9.
Full textBitar, Lynn, Joseph Zouein, Fady Gh Haddad, Roland Eid, and Hampig R. Kourie. "HER2 in metastatic colorectal cancer: a new to target to remember." Biomarkers in Medicine 15, no. 2 (February 2021): 135–38. http://dx.doi.org/10.2217/bmm-2020-0491.
Full textPerillo, Federica, Chiara Amoroso, Francesco Strati, Maria Rita Giuffrè, Angélica Díaz-Basabe, Georgia Lattanzi, and Federica Facciotti. "Gut Microbiota Manipulation as a Tool for Colorectal Cancer Management: Recent Advances in Its Use for Therapeutic Purposes." International Journal of Molecular Sciences 21, no. 15 (July 29, 2020): 5389. http://dx.doi.org/10.3390/ijms21155389.
Full textMedin, Caroline, Michael K. Turgeon, Jessica M. Keilson, Bhakti Dwivedi, Cameron Herting, Shishir K. Maithel, and Gregory B. Lesinski. "High-risk gene expression in colorectal liver metastasis: Potential for novel therapies." Journal of Clinical Oncology 40, no. 4_suppl (February 1, 2022): 147. http://dx.doi.org/10.1200/jco.2022.40.4_suppl.147.
Full textDe Pauw, Ines, Filip Lardon, Jolien Van den Bossche, Hasan Baysal, Patrick Pauwels, Marc Peeters, Jan Baptist Vermorken, and An Wouters. "Overcoming Intrinsic and Acquired Cetuximab Resistance in RAS Wild-Type Colorectal Cancer: An In Vitro Study on the Expression of HER Receptors and the Potential of Afatinib." Cancers 11, no. 1 (January 15, 2019): 98. http://dx.doi.org/10.3390/cancers11010098.
Full textVekic, Jelena, Aleksandra Zeljkovic, Aleksandra Stefanovic, Rosaria Vincenza Giglio, Marcello Ciaccio, and Manfredi Rizzo. "Diabetes and Colorectal Cancer Risk: A New Look at Molecular Mechanisms and Potential Role of Novel Antidiabetic Agents." International Journal of Molecular Sciences 22, no. 22 (November 17, 2021): 12409. http://dx.doi.org/10.3390/ijms222212409.
Full textHu, Bangli, Yixin Yin, Siqi Li, and Xianwen Guo. "Insights on Ferroptosis and Colorectal Cancer: Progress and Updates." Molecules 28, no. 1 (December 28, 2022): 243. http://dx.doi.org/10.3390/molecules28010243.
Full textNaydenov, Nayden, Susana Lechuga, Emina Huang, and Andrei Ivanov. "Myosin Motors: Novel Regulators and Therapeutic Targets in Colorectal Cancer." Cancers 13, no. 4 (February 11, 2021): 741. http://dx.doi.org/10.3390/cancers13040741.
Full textKang, Bo, Xiaobing Zhang, Weibing Wang, Shiqi She, Wenjie Chen, Cheng Chen, Yisha Wang, Xiaoyun Pan, Ouyuan Xu, and Yingjie Wang. "The Novel IGF-1R Inhibitor PB-020 Acts Synergistically with Anti-PD-1 and Mebendazole against Colorectal Cancer." Cancers 14, no. 23 (November 23, 2022): 5747. http://dx.doi.org/10.3390/cancers14235747.
Full textOh, Hyung-Hoon, and Young-Eun Joo. "Novel biomarkers for the diagnosis and prognosis of colorectal cancer." Intestinal Research 18, no. 2 (April 30, 2020): 168–83. http://dx.doi.org/10.5217/ir.2019.00080.
Full textHuang, Jiuhong, Juanli Wang, Guiting Song, Chunsheng Hu, Zhigang Xu, Zhongzhu Chen, Chuan Xu, and Donglin Yang. "Antiproliferative Evaluation of Novel 4-Imidazolidinone Derivatives as Anticancer Agent Which Triggers ROS-Dependent Apoptosis in Colorectal Cancer Cell." Molecules 27, no. 24 (December 13, 2022): 8844. http://dx.doi.org/10.3390/molecules27248844.
Full textZhao, Lan, and Yi Pan. "SSCS: A Stage Supervised Subtyping System for Colorectal Cancer." Biomedicines 9, no. 12 (December 2, 2021): 1815. http://dx.doi.org/10.3390/biomedicines9121815.
Full textXiao, Boduan, Leilei Zhang, Huihui Liu, Huiling Fang, Chunming Wang, Biao Huang, Xinyuan Liu, Xiumei Zhou, and Yigang Wang. "Oncolytic Adenovirus CD55-Smad4 Suppresses Cell Proliferation, Metastasis, and Tumor Stemness in Colorectal Cancer by Regulating Wnt/β-Catenin Signaling Pathway." Biomedicines 8, no. 12 (December 11, 2020): 593. http://dx.doi.org/10.3390/biomedicines8120593.
Full textLoong, Herbert H., Brigette B. Ma, and Anthony T. C. Chan. "Update in Antiepidermal Growth Factor Receptor Therapy in the Management of Metastatic Colorectal Cancer." Journal of Oncology 2009 (2009): 1–6. http://dx.doi.org/10.1155/2009/967920.
Full textJansen, Lina, Daniel Boakye, Elizabeth Alwers, Prudence R. Carr, Christoph Reissfelder, Martin Schneider, Uwe M. Martens, Jenny Chang-Claude, Michael Hoffmeister, and Hermann Brenner. "Uptake Rates of Novel Therapies and Survival Among Privately Insured Versus Publicly Insured Patients With Colorectal Cancer in Germany." Journal of the National Comprehensive Cancer Network 19, no. 4 (April 2021): 411–20. http://dx.doi.org/10.6004/jnccn.2020.7636.
Full textLoupakis, Fotios, Kenneth Joel Bloom, Wendy Allen, Enya Scanlon, Isabel Stacey, Derry Mae Keeling, Nital Patel, and Jordan Clark. "Drugging the undruggable: A market readiness analysis for KRAS-G12C." Journal of Clinical Oncology 38, no. 15_suppl (May 20, 2020): e15667-e15667. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e15667.
Full textCatalano, Fabio, Roberto Borea, Silvia Puglisi, Andrea Boutros, Annalice Gandini, Malvina Cremante, Valentino Martelli, Stefania Sciallero, and Alberto Puccini. "Targeting the DNA Damage Response Pathway as a Novel Therapeutic Strategy in Colorectal Cancer." Cancers 14, no. 6 (March 9, 2022): 1388. http://dx.doi.org/10.3390/cancers14061388.
Full textSalman Roghani, Roham, Ali Sanjari moghaddam, Gabrielle Rupprecht, Erdem Altunel, So Young Kim, Shannon McCall, Beatrice Thomas, Katie Ware, Jason Somarelli, and David S. Hsu. "A precision medicine drug discovery pipeline to identify dual CDK2/9 inhibition as a novel treatment for colorectal cancer." Journal of Clinical Oncology 38, no. 15_suppl (May 20, 2020): e16056-e16056. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e16056.
Full textKim, Dae Dong, and Cathy Eng. "The Current State of Targeted Agents in Rectal Cancer." International Journal of Surgical Oncology 2012 (2012): 1–14. http://dx.doi.org/10.1155/2012/406830.
Full textLeonard, Niamh A., Eileen Reidy, Kerry Thompson, Emma McDermott, Eleonora Peerani, Elena Tomas Bort, Frances R. Balkwill, Daniela Loessner, and Aideen E. Ryan. "Stromal Cells Promote Matrix Deposition, Remodelling and an Immunosuppressive Tumour Microenvironment in a 3D Model of Colon Cancer." Cancers 13, no. 23 (November 29, 2021): 5998. http://dx.doi.org/10.3390/cancers13235998.
Full textGrizzle, William E., Upender Manne, Nirag C. Jhala, and Heidi L. Weiss. "Molecular Characterization of Colorectal Neoplasia in Translational Research." Archives of Pathology & Laboratory Medicine 125, no. 1 (January 1, 2001): 91–98. http://dx.doi.org/10.5858/2001-125-0091-mcocni.
Full textYu, Guan-Hua, Shuo-Feng Li, Ran Wei, and Zheng Jiang. "Diabetes and Colorectal Cancer Risk: Clinical and Therapeutic Implications." Journal of Diabetes Research 2022 (March 7, 2022): 1–16. http://dx.doi.org/10.1155/2022/1747326.
Full textLee, Hey Min, Stefania Napolitano, Alexy Sorokin, Melanie N. Woods, Saikat Chowdhury, Jumanah Y. Alshenaifi, Anand K. Singh, et al. "Abstract 3275: Bromodomain and extraterminal (BET) protein inhibition sensitize BRAFV600E colorectal cancer to standard targeted therapies." Cancer Research 82, no. 12_Supplement (June 15, 2022): 3275. http://dx.doi.org/10.1158/1538-7445.am2022-3275.
Full textWong, Ambrose H. N., Brigette Ma, and Rashid N. Lui. "New developments in targeted therapy for metastatic colorectal cancer." Therapeutic Advances in Medical Oncology 15 (January 2023): 175883592211485. http://dx.doi.org/10.1177/17588359221148540.
Full textMartin, Matthew, Mengyao Sun, Aishat Motolani, and Tao Lu. "The Pivotal Player: Components of NF-κB Pathway as Promising Biomarkers in Colorectal Cancer." International Journal of Molecular Sciences 22, no. 14 (July 11, 2021): 7429. http://dx.doi.org/10.3390/ijms22147429.
Full textXia, Xiaoyang, DongShan You, Jing Cao, JingHui Huang, Junling Zhang, Mengli Huang, Yanan Chen, Xihua Xia, and Yuezong Bai. "Abstract 5088: Identification of NOTCH mutation as novel predictor to efficacious immunotherapy in colorectal cancer." Cancer Research 82, no. 12_Supplement (June 15, 2022): 5088. http://dx.doi.org/10.1158/1538-7445.am2022-5088.
Full textMisbah, Md, Manoj Kumar, Kuen-Huar Lee, and Shing-Chuan Shen. "Identification of Novel miRNAs, Targeting Genes, Signaling Pathway, and the Small Molecule for Overcoming Oxaliplatin Resistance of Metastatic Colorectal Cancer." BioMed Research International 2022 (September 19, 2022): 1–20. http://dx.doi.org/10.1155/2022/3825760.
Full textFrancescangeli, Federica, Maria Laura De Angelis, and Ann Zeuner. "Dietary Factors in the Control of Gut Homeostasis, Intestinal Stem Cells, and Colorectal Cancer." Nutrients 11, no. 12 (December 3, 2019): 2936. http://dx.doi.org/10.3390/nu11122936.
Full textEide, Peter, Jarle Bruun, Anita Sveen, Astrid Murumägi, John Mpindi, Mariliina Arjama, Olli Kallioniemi, and Ragnhild A. Lothe. "Novel drug discovery by pharmacogenomic profiling of 36 colorectal cancer cell lines." Journal of Clinical Oncology 34, no. 4_suppl (February 1, 2016): 604. http://dx.doi.org/10.1200/jco.2016.34.4_suppl.604.
Full textXu, Jianing, Zhehao Zhang, Dong Shen, Ting Zhang, Jinsong Zhang, and Wei De. "Long noncoding RNA LINC01296 plays an oncogenic role in colorectal cancer by suppressing p15 expression." Journal of International Medical Research 49, no. 5 (May 2021): 030006052110044. http://dx.doi.org/10.1177/03000605211004414.
Full textChoi, Jang-Hyun, Tae-Young Jang, So-El Jeon, Jee-Heun Kim, Choong-Jae Lee, Hyeon-Ji Yun, Ji-Youn Jung, So-Yeon Park, and Jeong-Seok Nam. "The Small-Molecule Wnt Inhibitor ICG-001 Efficiently Inhibits Colorectal Cancer Stemness and Metastasis by Suppressing MEIS1 Expression." International Journal of Molecular Sciences 22, no. 24 (December 14, 2021): 13413. http://dx.doi.org/10.3390/ijms222413413.
Full textDas, Plabon Kumar, Farhadul Islam, and Alfred K. Lam. "The Roles of Cancer Stem Cells and Therapy Resistance in Colorectal Carcinoma." Cells 9, no. 6 (June 3, 2020): 1392. http://dx.doi.org/10.3390/cells9061392.
Full textKhawaja, Hajrah, Rebecca Briggs, Cheryl Latimer, Md A. M. B. Rassel, Daryl Griffin, Lyndsey Hanson, Alberto Bardelli, et al. "Bcl-xL and association with apoptosis following KRASG12C inhibition in KRASG12C mutant colorectal cancer." Journal of Clinical Oncology 40, no. 16_suppl (June 1, 2022): 3557. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.3557.
Full textKhawaja, Hajrah, Rebecca Briggs, Cheryl Latimer, Md A. M. B. Rassel, Daryl Griffin, Lyndsey Hanson, Alberto Bardelli, et al. "Bcl-xL and association with apoptosis following KRASG12C inhibition in KRASG12C mutant colorectal cancer." Journal of Clinical Oncology 40, no. 16_suppl (June 1, 2022): 3557. http://dx.doi.org/10.1200/jco.2022.40.16_suppl.3557.
Full textShin, Alice E., Kensuke Sugiura, Yasunori Masuike, Kensuke Suzuki, Christopher J. Lengner, and Anil K. Rustgi. "Abstract B007: LIN28B promotes collective cell invasion and colorectal cancer metastasis via a novel CLDN1 and NOTCH3 axis." Cancer Research 82, no. 23_Supplement_1 (December 1, 2022): B007. http://dx.doi.org/10.1158/1538-7445.crc22-b007.
Full textAparicio, Cristina, Marina Belver, Lucía Enríquez, Francisco Espeso, Lucía Núñez, Ana Sánchez, Miguel Ángel de la Fuente, and Margarita González-Vallinas. "Cell Therapy for Colorectal Cancer: The Promise of Chimeric Antigen Receptor (CAR)-T Cells." International Journal of Molecular Sciences 22, no. 21 (October 29, 2021): 11781. http://dx.doi.org/10.3390/ijms222111781.
Full textBarchitta, Maugeri, Destri, Basile, and Agodi. "Epigenetic Biomarkers in Colorectal Cancer Patients Receiving Adjuvant or Neoadjuvant Therapy: A Systematic Review of Epidemiological Studies." International Journal of Molecular Sciences 20, no. 15 (August 6, 2019): 3842. http://dx.doi.org/10.3390/ijms20153842.
Full textGreally, Megan, Yaelle Tuvy, Brittanie M. Millang, Eileen Mary O'Reilly, Rona Yaeger, Leonard B. Saltz, and Geoffrey Yuyat Ku. "Actionable alterations (AA) in gastrointestinal (GI) cancers: Rate of detection and receipt of matched therapies (MT)." Journal of Clinical Oncology 38, no. 15_suppl (May 20, 2020): e15677-e15677. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.e15677.
Full textSubramanian, Subbaya, Xianda Zhao, and Ce Yaun. "Tumor exosome mediated immune regulation in colorectal cancer." Journal of Immunology 202, no. 1_Supplement (May 1, 2019): 194.15. http://dx.doi.org/10.4049/jimmunol.202.supp.194.15.
Full textMokgautsi, Ntlotlang, Yu-Cheng Kuo, Chien-Hsin Chen, Yan-Jiun Huang, Alexander T. H. Wu, and Hsu-Shan Huang. "Multiomics Study of a Novel Naturally Derived Small Molecule, NSC772864, as a Potential Inhibitor of Proto-Oncogenes Regulating Cell Cycle Progression in Colorectal Cancer." Cells 12, no. 2 (January 16, 2023): 340. http://dx.doi.org/10.3390/cells12020340.
Full textAparicio, Jorge, Francis Esposito, Sara Serrano, Esther Falco, Pilar Escudero, Ana Ruiz-Casado, Hermini Manzano, and Ana Fernandez-Montes. "Metastatic Colorectal Cancer. First Line Therapy for Unresectable Disease." Journal of Clinical Medicine 9, no. 12 (November 30, 2020): 3889. http://dx.doi.org/10.3390/jcm9123889.
Full textHuijberts, Sanne CFA, Robin MJM van Geel, Rene Bernards, Jos H. Beijnen, and Neeltje Steeghs. "Encorafenib, binimetinib and cetuximab combined therapy for patients with BRAFV600E mutant metastatic colorectal cancer." Future Oncology 16, no. 6 (February 2020): 161–73. http://dx.doi.org/10.2217/fon-2019-0748.
Full textSun, Yan, Hongping Li, Zhiming Ma, Jianfei Wang, Huiyu Yang, Xiaopeng Zhang, and Bingrong Liu. "Identification of immune subtypes and their prognosis and molecular implications in colorectal cancer." PLOS ONE 17, no. 11 (November 23, 2022): e0278114. http://dx.doi.org/10.1371/journal.pone.0278114.
Full textRoss, Jeffrey S., Doron Lipson, Christine E. Sheehan, Geoff Otto, Roman Yelensky, Alex Parker, Mirna Jarosz, et al. "Use of next-generation sequencing (NGS) to detect a novel ALK fusion and a high frequency of other actionable alterations in colorectal cancer (CRC)." Journal of Clinical Oncology 30, no. 15_suppl (May 20, 2012): 3533. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.3533.
Full textDienstmann, Rodrigo, Ramon Salazar, and Josep Tabernero. "Molecular Subtypes and the Evolution of Treatment Decisions in Metastatic Colorectal Cancer." American Society of Clinical Oncology Educational Book, no. 38 (May 2018): 231–38. http://dx.doi.org/10.1200/edbk_200929.
Full textEberhardt, Wolfgang, Kristina Haeussler, Usman Nasrullah, and Josef Pfeilschifter. "Multifaceted Roles of TRIM Proteins in Colorectal Carcinoma." International Journal of Molecular Sciences 21, no. 20 (October 13, 2020): 7532. http://dx.doi.org/10.3390/ijms21207532.
Full textHe, Liying, Hui Li, Jianye Cai, Liang Chen, Jia Yao, Yingcai Zhang, Wanfu Xu, et al. "Prognostic Value of the Glasgow Prognostic Score or Modified Glasgow Prognostic Score for Patients with Colorectal Cancer Receiving Various Treatments: a Systematic Review and Meta-Analysis." Cellular Physiology and Biochemistry 51, no. 3 (2018): 1237–49. http://dx.doi.org/10.1159/000495500.
Full textMármol, Inés, Nerea Jiménez-Moreno, Carmen Ancín-Azpilicueta, Jesús Osada, Elena Cerrada, and María Jesús Rodríguez-Yoldi. "A Combination of Rosa Canina Extracts and Gold Complex Favors Apoptosis of Caco-2 Cells by Increasing Oxidative Stress and Mitochondrial Dysfunction." Antioxidants 9, no. 1 (December 24, 2019): 17. http://dx.doi.org/10.3390/antiox9010017.
Full textFasano, Candida, Valentina Grossi, Giovanna Forte, and Cristiano Simone. "Short Linear Motifs in Colorectal Cancer Interactome and Tumorigenesis." Cells 11, no. 23 (November 23, 2022): 3739. http://dx.doi.org/10.3390/cells11233739.
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