Journal articles on the topic 'NOTCH 1 Intracellular Domain Indicate'
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Kitagawa, Motoo, Toshinao Oyama, Taichi Kawashima, Barry Yedvobnick, Anumeha Kumar, Kenji Matsuno, and Kenichi Harigaya. "A Human Protein with Sequence Similarity to DrosophilaMastermind Coordinates the Nuclear Form of Notch and a CSL Protein To Build a Transcriptional Activator Complex on Target Promoters." Molecular and Cellular Biology 21, no. 13 (July 1, 2001): 4337–46. http://dx.doi.org/10.1128/mcb.21.13.4337-4346.2001.
Full textBlokzijl, Andries, Camilla Dahlqvist, Eva Reissmann, Anna Falk, Annalena Moliner, Urban Lendahl, and Carlos F. Ibáñez. "Cross-talk between the Notch and TGF-β signaling pathways mediated by interaction of the Notch intracellular domain with Smad3." Journal of Cell Biology 163, no. 4 (November 24, 2003): 723–28. http://dx.doi.org/10.1083/jcb.200305112.
Full textChandiran, Karthik, and Lisa M. Minter. "Notch-1 regulation of microRNAs alter the expression of proinflammatory cytokines and Th1 response." Journal of Immunology 196, no. 1_Supplement (May 1, 2016): 127.1. http://dx.doi.org/10.4049/jimmunol.196.supp.127.1.
Full textKoshizaka, Masaya, Minoru Takemoto, Seiya Sato, Hirotake Tokuyama, Masaki Fujimoto, Emiko Okabe, Ryoichi Ishibashi, et al. "An Angiotensin II Type 1 Receptor Blocker Prevents Renal Injury via Inhibition of the Notch Pathway in Ins2 Akita Diabetic Mice." Experimental Diabetes Research 2012 (2012): 1–10. http://dx.doi.org/10.1155/2012/159874.
Full textNobta, Masuhiro, Tomoo Tsukazaki, Yasuaki Shibata, Chang Xin, Takeshi Moriishi, Seiji Sakano, Hiroyuki Shindo, and Akira Yamaguchi. "Critical Regulation of Bone Morphogenetic Protein-induced Osteoblastic Differentiation by Delta1/Jagged1-activated Notch1 Signaling." Journal of Biological Chemistry 280, no. 16 (February 4, 2005): 15842–48. http://dx.doi.org/10.1074/jbc.m412891200.
Full textKusano, Shuichi, and Nancy Raab-Traub. "An Epstein-Barr Virus Protein Interacts with Notch." Journal of Virology 75, no. 1 (January 1, 2001): 384–95. http://dx.doi.org/10.1128/jvi.75.1.384-395.2001.
Full textKim, Su Hwan, Jin Hyun Kang, Tae Ki Uhm, Do Jin Kim, and Il Yup Chung. "Notch signaling promotes MUC5AC expression through epidermal growth factor receptor-extracellular regulated kinase pathway (163.1)." Journal of Immunology 186, no. 1_Supplement (April 1, 2011): 163.1. http://dx.doi.org/10.4049/jimmunol.186.supp.163.1.
Full textHoebeke, Inge, Magda De Smedt, Inge Van de Walle, Katia Reynvoet, Greet De Smet, Jean Plum, and Georges Leclercq. "Overexpression of HES-1 is not sufficient to impose T-cell differentiation on human hematopoietic stem cells." Blood 107, no. 7 (April 1, 2006): 2879–81. http://dx.doi.org/10.1182/blood-2005-05-1815.
Full textKindler, Thomas, Melanie G. Cornejo, Claudia Scholl, Jianing Liu, Dena S. Leeman, J. Erika Haydu, Stefan Fröhling, Benjamin H. Lee, and D. Gary Gilliland. "K-RasG12D–induced T-cell lymphoblastic lymphoma/leukemias harbor Notch1 mutations and are sensitive to γ-secretase inhibitors." Blood 112, no. 8 (October 15, 2008): 3373–82. http://dx.doi.org/10.1182/blood-2008-03-147587.
Full textWallberg, Annika E., Kia Pedersen, Urban Lendahl, and Robert G. Roeder. "p300 and PCAF Act Cooperatively To Mediate Transcriptional Activation from Chromatin Templates by Notch Intracellular Domains In Vitro." Molecular and Cellular Biology 22, no. 22 (November 15, 2002): 7812–19. http://dx.doi.org/10.1128/mcb.22.22.7812-7819.2002.
Full textKamińska, Alicja, Sylwia Marek, Laura Pardyak, Małgorzata Brzoskwinia, Barbara Bilinska, and Anna Hejmej. "Crosstalk between Androgen-ZIP9 Signaling and Notch Pathway in Rodent Sertoli Cells." International Journal of Molecular Sciences 21, no. 21 (November 5, 2020): 8275. http://dx.doi.org/10.3390/ijms21218275.
Full textChang, Chunkang, Chengming Fei, Juan Guo, Youshan Zhao, Shucheng Gu, and Xiao Li. "Activation of Notch-Hes Signaling Pathway Impairs Osteogenic Differentiation and Hematopoietic Stem Cell-Supporting Capacitiy of Mesenchymal Stromal Cells Derived from Myelodysplastic Syndromes Patients." Blood 126, no. 23 (December 3, 2015): 2857. http://dx.doi.org/10.1182/blood.v126.23.2857.2857.
Full textJeffries, Shawn, David J. Robbins, and Anthony J. Capobianco. "Characterization of a High-Molecular-Weight Notch Complex in the Nucleus of Notchic-Transformed RKE Cells and in a Human T-Cell Leukemia Cell Line." Molecular and Cellular Biology 22, no. 11 (June 1, 2002): 3927–41. http://dx.doi.org/10.1128/mcb.22.11.3927-3941.2002.
Full textJundt, Franziska, Oezlem Acikgoez, Robert Preissner, and Bernd Dorken. "Manipulation of the Notch Pathway by γ-Secretase Inhibitors as a Novel Therapeutic Approach in Multiple Myeloma." Blood 104, no. 11 (November 16, 2004): 645. http://dx.doi.org/10.1182/blood.v104.11.645.645.
Full textZhu, Xiaolong, Sha Ding, Cong Qiu, Yanna Shi, Lin Song, Yueyue Wang, Yuewen Wang, et al. "SUMOylation Negatively Regulates Angiogenesis by Targeting Endothelial NOTCH Signaling." Circulation Research 121, no. 6 (September 2017): 636–49. http://dx.doi.org/10.1161/circresaha.117.310696.
Full textZanotti, Stefano, and Ernesto Canalis. "Notch and the Skeleton." Molecular and Cellular Biology 30, no. 4 (December 7, 2009): 886–96. http://dx.doi.org/10.1128/mcb.01285-09.
Full textHsu, Kai-Wen, Rong-Hong Hsieh, Yan-Hwa Wu Lee, Chi-Hong Chao, Kou-Juey Wu, Min-Jen Tseng, and Tien-Shun Yeh. "The Activated Notch1 Receptor Cooperates with α-Enolase and MBP-1 in Modulating c-myc Activity." Molecular and Cellular Biology 28, no. 15 (May 19, 2008): 4829–42. http://dx.doi.org/10.1128/mcb.00175-08.
Full textMaillard, Ivan, Seth E. Pross, Olga Shestova, Hong Sai, Jon C. Aster, Avinash Bhandoola, and Warren S. Pear. "Canonical Notch Signaling Is Dispensable for the Maintenance of Adult Hematopoietic Stem Cells." Blood 106, no. 11 (November 16, 2005): 267. http://dx.doi.org/10.1182/blood.v106.11.267.267.
Full textHsieh, J. J., T. Henkel, P. Salmon, E. Robey, M. G. Peterson, and S. D. Hayward. "Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2." Molecular and Cellular Biology 16, no. 3 (March 1996): 952–59. http://dx.doi.org/10.1128/mcb.16.3.952.
Full textNakamura, Makoto, Lizi Wu, Satoru Kojika, James D. Griffin, and Kanji Sugita. "Activation of Notch1 Signaling Suppresses Granulocytic Differentiation and Maintains a Part of Myeloid Progenitor Cells At the Immature Stage." Blood 118, no. 21 (November 18, 2011): 2375. http://dx.doi.org/10.1182/blood.v118.21.2375.2375.
Full textCallahan, Robert, Barry A. Chestnut, and Ahmed Raafat. "Original Research: Featured Article: Imatinib mesylate (Gleevec) inhibits Notch and c-Myc signaling: Five-day treatment permanently rescues mammary development." Experimental Biology and Medicine 242, no. 1 (August 22, 2016): 53–67. http://dx.doi.org/10.1177/1535370216665175.
Full textLin, Michelle I., Charles W. Carspecken, Audrey Uong, Emily Price, and Leonard I. Zon. "Genetic Interaction Between Angiopoietin-Like Proteins 1 and 2 and Notch Signaling During HSC Development." Blood 116, no. 21 (November 19, 2010): 573. http://dx.doi.org/10.1182/blood.v116.21.573.573.
Full textHuntsman, Heather D., Daisuke Araki, Richard H. Smith, and Andre Larochelle. "Hypoxia and Notch Signaling Synergistically Expand Long-Term Repopulating Human Hematopoietic Stem/Progenitor Cells." Blood 132, Supplement 1 (November 29, 2018): 2557. http://dx.doi.org/10.1182/blood-2018-99-119388.
Full textSpengler, Katrin, Nderim Kryeziu, Silke Große, Alexander S. Mosig, and Regine Heller. "VEGF Triggers Transient Induction of Autophagy in Endothelial Cells via AMPKα1." Cells 9, no. 3 (March 11, 2020): 687. http://dx.doi.org/10.3390/cells9030687.
Full textMangum, Kevin D., Emily J. Freeman, Justin C. Magin, Joan M. Taylor, and Christopher P. Mack. "Transcriptional and posttranscriptional regulation of the SMC-selective blood pressure-associated gene, ARHGAP42." American Journal of Physiology-Heart and Circulatory Physiology 318, no. 2 (February 1, 2020): H413—H424. http://dx.doi.org/10.1152/ajpheart.00143.2019.
Full textMaeda, Takahiro, Taha Merghoub, Lin Dong, Manami Maeda, Robin Hobbs, Johannes Zakrzewski, Marcel van den Brink, et al. "LRF/Pokemon Plays a Pivotal Role in B Versus T Lymphoid Lineage Fate Decision at the Early Lymphoid Progenitor Stage by Opposing Notch1 Signaling." Blood 108, no. 11 (November 16, 2006): 778. http://dx.doi.org/10.1182/blood.v108.11.778.778.
Full textD'Avola, Annalisa, Alison Yeomans, Samantha Drennan, Matthew Rose-Zerilli, Jonathan C. Strefford, Freda K. Stevenson, Andrew J. Steele, Graham Packham, and Francesco Forconi. "Global and MYC-Specific Translation Is Enhanced in Activated Chronic Lymphocytic Leukemia Cells Carrying NOTCH1 C.7541_7542delct Mutations." Blood 128, no. 22 (December 2, 2016): 970. http://dx.doi.org/10.1182/blood.v128.22.970.970.
Full textRoss, David A., and Tom Kadesch. "The Notch Intracellular Domain Can Function as a Coactivator for LEF-1." Molecular and Cellular Biology 21, no. 22 (November 15, 2001): 7537–44. http://dx.doi.org/10.1128/mcb.21.22.7537-7544.2001.
Full textTagami, Shinji, Masayasu Okochi, Kanta Yanagida, Akiko Ikuta, Akio Fukumori, Naohiko Matsumoto, Yoshiko Ishizuka-Katsura, et al. "Regulation of Notch Signaling by Dynamic Changes in the Precision of S3 Cleavage of Notch-1." Molecular and Cellular Biology 28, no. 1 (October 29, 2007): 165–76. http://dx.doi.org/10.1128/mcb.00863-07.
Full textKothari, Alok, Hamza Celik, Andrew Martens, Cates Mallaney, Elizabeth L. Ostrander, Elizabeth Eultgen, and Grant A. Challen. "Pathways for Oncogenesis in T-Cell Acute Lymphoblastic Leukemia Driven By DNA Methylation and Notch Signaling." Blood 126, no. 23 (December 3, 2015): 1226. http://dx.doi.org/10.1182/blood.v126.23.1226.1226.
Full textOswald, Franz, Birgitt Täuber, Thomas Dobner, Soizic Bourteele, Ulrike Kostezka, Guido Adler, Susanne Liptay, and Roland M. Schmid. "p300 Acts as a Transcriptional Coactivator for Mammalian Notch-1." Molecular and Cellular Biology 21, no. 22 (November 15, 2001): 7761–74. http://dx.doi.org/10.1128/mcb.21.22.7761-7774.2001.
Full textBeatus, P., J. Lundkvist, C. Oberg, and U. Lendahl. "The notch 3 intracellular domain represses notch 1-mediated activation through Hairy/Enhancer of split (HES) promoters." Development 126, no. 17 (September 1, 1999): 3925–35. http://dx.doi.org/10.1242/dev.126.17.3925.
Full textSchroeter, Eric H., Jeffrey A. Kisslinger, and Raphael Kopan. "Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain." Nature 393, no. 6683 (May 1998): 382–86. http://dx.doi.org/10.1038/30756.
Full textNakazawa, Minako, Hiroyasu Ishii, Hiroyuki Aono, Miwa Takai, Takahiro Honda, Satoko Aratani, Akiyoshi Fukamizu, et al. "Role of notch-1 intracellular domain in activation of rheumatoid synoviocytes." Arthritis & Rheumatism 44, no. 7 (2001): 1545–54. http://dx.doi.org/10.1002/1529-0131(200107)44:7<1545::aid-art278>3.0.co;2-q.
Full textCrow, Jacob J., and Allan R. Albig. "Notch family members follow stringent requirements for intracellular domain dimerization at sequence-paired sites." PLOS ONE 15, no. 11 (November 24, 2020): e0234101. http://dx.doi.org/10.1371/journal.pone.0234101.
Full textChu, Jianlin, Shawn Jeffries, Jason E. Norton, Anthony J. Capobianco, and Emery H. Bresnick. "Repression of Activator Protein-1-mediated Transcriptional Activation by the Notch-1 Intracellular Domain." Journal of Biological Chemistry 277, no. 9 (December 5, 2001): 7587–97. http://dx.doi.org/10.1074/jbc.m111044200.
Full textChapman, Gavin, Lining Liu, Cecilia Sahlgren, Camilla Dahlqvist, and Urban Lendahl. "High levels of Notch signaling down-regulate Numb and Numblike." Journal of Cell Biology 175, no. 4 (November 20, 2006): 535–40. http://dx.doi.org/10.1083/jcb.200602009.
Full textEngel, Michael E., Hong Nguyen, Jolene Mariotti, Aubrey A. Hunt, and Scott Hiebert. "Myeloid Translocation Gene (MTG)-16 Binds Intracellular Domains of Notch Receptors to Coordinate Notch-Dependent Cell Fate Specification." Blood 114, no. 22 (November 20, 2009): 257. http://dx.doi.org/10.1182/blood.v114.22.257.257.
Full textZucchetto, Antonella, Chiara Caldana, Federico Pozzo, Silvia Rasi, Carmela Ciardullo, Dania Benedetti, Erika Tissino, et al. "NOTCH1 Mutations Are Associated with High CD49d Expression in Chronic Lymphocytic Leukemia." Blood 124, no. 21 (December 6, 2014): 1978. http://dx.doi.org/10.1182/blood.v124.21.1978.1978.
Full textFassa, Angeliki, Loukia Parisiadou, Nikolaos K. Robakis, and Spiros Efthimiopoulos. "Novel Processing of Notch 1 within Its Intracellular Domain by a Cysteine Protease." Neurodegenerative Diseases 4, no. 2-3 (2007): 148–55. http://dx.doi.org/10.1159/000101839.
Full textRessel, L., R. W. Else, A. Poli, and D. J. Argyle. "Aberrant Subcellular Immunolocalization of NOTCH-1 Activated Intracellular Domain in Feline Mammary Tumours." Journal of Comparative Pathology 150, no. 4 (May 2014): 366–72. http://dx.doi.org/10.1016/j.jcpa.2013.11.213.
Full textVarnum-Finney, B., L. Wu, M. Yu, C. Brashem-Stein, S. Staats, D. Flowers, J. D. Griffin, and I. D. Bernstein. "Immobilization of Notch ligand, Delta-1, is required for induction of notch signaling." Journal of Cell Science 113, no. 23 (December 1, 2000): 4313–18. http://dx.doi.org/10.1242/jcs.113.23.4313.
Full textCheng, Jing, Qianfu Wu, Rong Lv, Li Huang, Banglong Xu, Xianbao Wang, Aihua Chen, and Fei He. "MicroRNA-449a Inhibition Protects H9C2 Cells Against Hypoxia/Reoxygenation-Induced Injury by Targeting the Notch-1 Signaling Pathway." Cellular Physiology and Biochemistry 46, no. 6 (2018): 2587–600. http://dx.doi.org/10.1159/000489686.
Full textWu, Lizi, Tao Sun, Karla Kobayashi, Ping Gao, and James D. Griffin. "Identification of a Family of Mastermind-Like Transcriptional Coactivators for Mammalian Notch Receptors." Molecular and Cellular Biology 22, no. 21 (November 1, 2002): 7688–700. http://dx.doi.org/10.1128/mcb.22.21.7688-7700.2002.
Full textMatsuno, K., R. J. Diederich, M. J. Go, C. M. Blaumueller, and S. Artavanis-Tsakonas. "Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats." Development 121, no. 8 (August 1, 1995): 2633–44. http://dx.doi.org/10.1242/dev.121.8.2633.
Full textKeilani, Serene, DeLacy Healey, and Kiminobu Sugaya. "Reelin regulates differentiation of neural stem cells by activation of notch signaling through Disabled-1 tyrosine phosphorylation." Canadian Journal of Physiology and Pharmacology 90, no. 3 (March 2012): 361–69. http://dx.doi.org/10.1139/y2012-001.
Full textDe Strooper, Bart, Wim Annaert, Philippe Cupers, Paul Saftig, Katleen Craessaerts, Jeffrey S. Mumm, Eric H. Schroeter, et al. "A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain." Nature 398, no. 6727 (April 1999): 518–22. http://dx.doi.org/10.1038/19083.
Full textZhang, C., J. Chang, W. Sonoyama, S. Shi, and C. Y. Wang. "Inhibition of Human Dental Pulp Stem Cell Differentiation by Notch Signaling." Journal of Dental Research 87, no. 3 (March 2008): 250–55. http://dx.doi.org/10.1177/154405910808700312.
Full textDer Vartanian, Audrey, Aymeric Audfray, Bilal Al Jaam, Mathilde Janot, Sébastien Legardinier, Abderrahman Maftah, and Agnès Germot. "ProteinO-Fucosyltransferase 1 Expression Impacts Myogenic C2C12 Cell Commitment via the Notch Signaling Pathway." Molecular and Cellular Biology 35, no. 2 (November 10, 2014): 391–405. http://dx.doi.org/10.1128/mcb.00890-14.
Full textBertagna, Angela, Dima Toptygin, Ludwig Brand, and Doug Barrick. "The effects of conformational heterogeneity on the binding of the Notch intracellular domain to effector proteins: a case of biologically tuned disorder." Biochemical Society Transactions 36, no. 2 (March 20, 2008): 157–66. http://dx.doi.org/10.1042/bst0360157.
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