Academic literature on the topic 'Non-invasive ventilation therapy'

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Journal articles on the topic "Non-invasive ventilation therapy"

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Mehta, Akshay. "Synopsis on Non-invasive Ventilation in Neonatology." International Journal of Clinical Case Reports and Reviews 7, no. 04 (July 17, 2021): 01–06. http://dx.doi.org/10.31579/2690-4861/128.

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Non-invasive ventilation (NIV) is a mode of respiratory support commonly used on the neonatal unit. Since the advent of NIV, it has evolved from being used as a mode of respiratory support to wean infants from mechanical ventilation (MV) to a primary mode of respiratory support. NIV improve the functional residual capacity in the newborn (at term or preterm) avoiding invasive actions such as tracheal intubation. Newer methods of NIV support such as nasal bilevel positive airway pressure (BiPAP) and humidified high flow nasal cannula oxygen therapy (HHFNC) have emerged in attempts to reduce intubation rates and subsequent MV in preterm infants. With this synopsis, we aim to discuss various available NIV modes of ventilation in Neonatology, including indications, physiological principle, practical aspects and effects on important short and long-term morbidities associated with the use of NIV.
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Аvdeev, S. N. "AEROSOL THERAPY DURING NON-INVASIVE VENTILATION." Messenger of ANESTHESIOLOGY AND RESUSCITATION 15, no. 2 (May 23, 2018): 45–54. http://dx.doi.org/10.21292/2078-5658-2018-15-2-45-54.

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White, Victoria. "Non-invasive Ventilation in Acute Respiratory Failure." Physiotherapy 86, no. 4 (April 2000): 221. http://dx.doi.org/10.1016/s0031-9406(05)60979-0.

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Nizami, Mohammed Ismail, Narendra Kumar N., Ashima Sharma, G. Vishwa Reddy, and S. Raghavendra Goud. "Non-Invasive Ventilation: First Line Therapy in the Acute Exacerbations of COPD in Emergency Department." Indian Journal of Emergency Medicine 3, no. 2 (2017): 217–22. http://dx.doi.org/10.21088/ijem.2395.311x.3217.7.

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Wood, C., S. Aristobil-Adele, J. Wittwer, K. Gray, and K. Waters. "P140 Non-invasive Ventilation prior to Adenotonsillectomy." SLEEP Advances 3, Supplement_1 (October 1, 2022): A74—A75. http://dx.doi.org/10.1093/sleepadvances/zpac029.208.

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Abstract Introduction Prolonged wait times to ENT surgery, combined with the risk for post-operative respiratory events in children with severe OSA led to a clinical pathway of implementing CPAP therapy in children with severe OSA whilst on waiting lists for adenotonsillectomy. This study evaluated the impact of this pathway on the clinical care of these patients. Methods A retrospective review of medical records of patients under 18yrs of age diagnosed with OSA and initiated on CPAP whilst awaiting review by ENT / Adenotonsillectomy, between January 2019 and December 2020. Results 36 patients were identified, age 4.3 ± 3.2 years, 86% male, and 80.6% had comorbidities. 16 (44.4%) were overweight or obese, and for 8 (22.2%) obesity was the primary comorbidity. Mean delays: Sleep study to Referral = 4.5 ± 10.5 weeks, Referral to NIV initiation 5.6 ± 8.7 weeks, and NIV to ENT surgery 13.6 ± 13.6 weeks. Total delay from referral to the surgery was 19.6 ± 19.4 weeks. 31 (86%) children were initiated on therapy in hospital, and five (13.9%) patients were non-compliant with the therapy. Discussion Current delays to ENT surgery for children identified with OSA on sleep study average 5 months. Where OSA is sufficient to recommend ENT surgery, the majority (80%) of children tolerated CPAP therapy while they await surgery. We suggest that the benefits obtained are that therapy can be instituted more rapidly than surgery, and where children are able to use CPAP therapy it reduced the requirement for high-dependency or intensive care admission post-operatively.
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Ciobanu, Laura. "Is there enough room for non-invasive ventilation in pulmonary rehabilitation?" Biotechnology and Bioprocessing 1, no. 2 (December 10, 2020): 01–06. http://dx.doi.org/10.31579/2766-2314/007.

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Pulmonary rehabilitation (PR) is a non-pharmacological intervention addressed to chronic obstructive pulmonary disease (COPD) and non-COPD chronic respiratory patients, a key management strategy scientifically demonstrated to improve exercise capacity, dyspnoea, health status and psychological wellbeing. The main body of literature comes from COPD patients, as they provide the core evidence for PR programmes. PR is recommended even to severe patients having chronic respiratory failure; their significant psychological impairment and potential for greater instability during the PR programme will be carefully considered by the multidisciplinary team. Optimizing medical management (e g, inhaled bronchodilators, oxygen therapy, non- invasive ventilation) may enhance the results of exercise training. Patients who already receive long-term domiciliary non- invasive ventilation (NIV) for chronic respiratory failure might exercise with NIV during exercise training if acceptable and tolerable to the patient. It is not advisable to offer long-term domiciliary NIV with the only aim to improve outcomes during PR course. There are different attempts to use both negative and positive NIV in limited clinical studies. Long-term adherence to exercise is an important goal of PR programmes and teams, targeting to translate all-domain gains of PR into increased physical activity and participation to real life. Being a reliable alternative for the future, studies should focus on pressure regimens, type of devices, acceptability and portability for everyday activities.
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Rauf-ul-Hassan, Muahmmad, Ahtesham Iqbal, Muhammad Waseem, Muhammad Zubair Ashraf, Tehreem Abaid, and Anam Saleem. "Non-Invasive Ventilation versus Invasive Mechanical Ventilation: Results from a Tertiary Care Hospital." Pakistan Journal of Medical and Health Sciences 16, no. 1 (January 18, 2022): 256–58. http://dx.doi.org/10.53350/pjmhs22161256.

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Objective: To compare the patient outcome in severe COVID-19 pneumonia between the non-invasive ventilation and invasive mechanical ventilation. Study design: Prospective, observational study Study Setting and Duration: Department of Pulmonology, Bahawal Victoria Hospital, Bahawalpur from January 2021 to June 2021. Methodology: We analyzed 660 patients of severe covid pneumonia. Conscious proning was done in those requiring ≥ 21 L oxygen and oxygen saturation < 90%. We defined typical ARDS according to Berlin criteria. Atypical ARDS did not fulfill set criteria. We divided ARDS into 2 types i-e H and L type. We managed ARDS with either NIV, invasive mechanical ventilation or both. We used multiple regression analysis to predict ICU stay. Results: Out of 660 patients, 285 (43.18%) developed biPAP failure and were subsequently intubated. We observed 273 (41.4%) overall mortality, 175 (64.1%) in IMV and 98 (35.9%) in the NIV group (p<0.0001). invasive mechanical ventilation had statistically significant correlation with mortality and also predicted ICU stay. (p=< 0.001, OR 3.2, p=0.001). Conclusion: NIV therapy is superior to invasive mechanical ventilation in terms of ICU stay and outcome. Keywords: ARDS, coronavirus, COVID-19, non-invasive ventilation, mechanical ventilation, pneumonia
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Majid, Norhaini, Roswati Nordin, Norshamatul Aidah Osran, and Suryanto Suryanto. "Helmet Non-invasive Ventilation Therapy: Measurement of comfort behaviour." Environment-Behaviour Proceedings Journal 6, no. 18 (December 12, 2021): 119–24. http://dx.doi.org/10.21834/ebpj.v6i18.3082.

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Comfort is integral towards tolerance in helmet non-invasive ventilation (NIV) therapy among acute respiratory failure (ARF) patients. This study aims to measure the patients’ comfort behaviour level after completion of helmet NIV therapy. It is a quantitative, descriptive, observational study involving 67 ARF patients. Kolcaba's Comfort Behavioural Checklist (CBC) was used, with the highest score of 120. The mean CBC score was 88.54, SD 7.35, indicating moderate comfort level; for Acute Pulmonary Oedema (APO) and non- APO, patients were 89.88, SD 7.25, and 87.08, SD 7.80 respectively. This reflects genuine patients' response towards therapy which is significant for future improvement. Keywords: Helmet Continuous Positive Airway Pressure; CPAP; Kolcaba’s Behavioural Checklist; Acute Respiratory Failure eISSN: 2398-4287© 2021. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians/Africans/Arabians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia. DOI: https://doi.org/10.21834/ebpj.v6i18.3082
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Brigg, Craig. "The benefits of non-invasive ventilation and CPAP therapy." British Journal of Nursing 8, no. 20 (November 11, 1999): 1355–61. http://dx.doi.org/10.12968/bjon.1999.8.20.1355.

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Tsygankov, К. A., I. N. Grachev, Vladimir I. Shatalov, А. V. Schegolev, D. A. Аveryanov, R. S. Lakotko, and М. А. Karnaushkina. "The impact of non-invasive respiratory support techniques on the lethal outcome frequency in adult with severe respiratory failure caused by the new coronavirus infection." Messenger of ANESTHESIOLOGY AND RESUSCITATION 18, no. 1 (March 6, 2021): 47–56. http://dx.doi.org/10.21292/2078-5658-2021-18-1-47-56.

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The objective: to evaluate the effect of high-flow oxygen and non-invasive ventilation on the mortality rate in adults with severe respiratory failure caused by the new coronavirus infection in the intensive care unit (ICU).Subjects and methods. A one-center retrospective study was conducted. Electronic medical files of patients treated in the ICU from April 1 to May 25, 2020, were analyzed. Totally, 101 medical files were selected, further, they were divided into two groups. Group 1 (n = 49) included patients who received oxygen insufflation, and should it fail, they received traditional artificial ventilation. No non-invasive respiratory therapy was used in this group. Group 2 (n = 52) included patients who received high-flow oxygen therapy and non-invasive ventilation. The mortality rate in the groups made a primary endpoint for assessing the impact of high-flow oxygen therapy and non-invasive ventilation. The following parameters were also analyzed: drug therapy, the number of patients in whom non-invasive techniques were used taking into account the frequency of cases when these techniques failed, and the number of patients in whom artificial ventilation was initiated.Results. In Group 2, non-invasive methods of respiratory therapy were used in 31 (60%) cases. High-flow oxygen therapy was used in 19 (36%) of them; in 13 cases this method allowed weaning them from the high flow. Non-invasive ventilation was used in 18 cases, in 12 patients it was used due to progressing severe respiratory failure during humidified oxygen insufflation, in 6 patients – after the failed high-flow oxygen therapy. In Group 1, 25 (51%) patients were intubated and transferred to artificial ventilation, in Group 2, 10 (19.2%) underwent the same. The lethal outcome was registered in 23 (47%) cases in Group 1, and in 10 (19.2%) in Group 2 (p = 0.004). Analysis of drug therapy in the groups revealed the difference in the prescription of pathogenetic therapy. Logistic regression demonstrated the effectiveness of the combination of tocilizumab + a glucocorticoid in reducing the frequency of lethal cases (p = 0.001).Conclusion. The use of non-invasive respiratory support in adults with severe respiratory failure caused by the new coronavirus infection combined with therapy by tocilizumab + a glucocorticoid can reduce the incidence of lethal cases.
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Dissertations / Theses on the topic "Non-invasive ventilation therapy"

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Marjanovic, Nicolas. "Approche globale du support ventilatoire en médecine d'urgence." Thesis, Poitiers, 2020. http://theses.univ-poitiers.fr/64158/2020-Marjanovic-Nicolas-These.

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L’insuffisance respiratoire aiguë est un motif fréquent de consultation dans un service d’urgences. Le traitement de première intention repose sur l’oxygénothérapie conventionnelle. En cas d’échec ou d’emblée en cas d’urgence vitale immédiate, le recours à un support ventilatoire devient nécessaire. Les supports ventilatoires englobent l’oxygénothérapie à haut-débit nasal humidifiée (OHD) et la ventilation mécanique qui peut être invasive ou non-invasive. Les données concernant l’intérêt du support ventilatoire en médecine d’urgence sont issues pour l’essentiel de travaux conduits en réanimation, et une approche globale de leur place en médecine d’urgence n’a jamais été réalisé.L’objectif de ce travail est de proposer une évaluation globale du support ventilatoire en médecine d’urgence, en analysant l’intérêt de l’OHD, d’introduction récente aux urgences, et la pratique aux urgences de la ventilation mécanique non-invasive et invasive.Nous avons dans un premier temps évalué les effets cliniques et gazométriques de l’OHD au cours de l’insuffisance respiratoire aiguë hypoxémique de novo, puis au cours de l’insuffisance respiratoire aiguë hypercapnique secondaire à un OAP cardiogénique, aux travers de deux études prospectives. Puis, nous avons réalisé une compilation des données de l’ensemble des études prospectives réalisés aux urgences pour déterminé si la mise en place précoce de l’OHD au cours des détresses respiratoires aiguës sans cause spécifique était susceptible d’améliorer le devenir des patients. Nous avons constaté qu’une mise en place précoce de l’OHD, dès l’admission du patient aux urgences, était associée à une amélioration des paramètres cliniques et gazométriques en cas d’insuffisance respiratoire aiguë de novo comparativement à l’oxygénothérapie conventionnelle, et de manière similaire à la ventilation non-invasive en cas d’insuffisance respiratoire aiguë hypercapnique secondaire à un OAP. En revanche, au cours des détresses respiratoires aiguës admises aux urgences, quelle qu’en soit la cause, l’OHD n’a pas été associé à une diminution au recours à la ventilation mécanique, ni à une diminution de la mortalité.Parallèlement, nous avons réalisé une évaluation des pratiques de la ventilation mécanique aux urgences, en analysant, indépendamment de l’indication de la ventilation mécanique, trois déterminants susceptibles d’influer le pronostic des patients. Nous avons dans un premier temps conduit un banc d’essai de l’ensemble des ventilateurs mécaniques de médecine d’urgence commercialisés en Europe et en Amérique du Nord pour évaluer leur performance et leur utilisabilité aux travers de deux études. Puis, nous avons réalisé une évaluation des pratiques de la ventilation mécanique, et mesuré l’association entre les paramètres réglés (notamment la ventilation à faible volume) et le pronostic du patient. Nous avons mis en évidence que les ventilateurs de médecine d’urgence récents ont une performance technique proche des ventilateurs de réanimation en raison des évolutions technologiques et de l’émergence des ventilateurs à turbine. L’augmentation de leurs performances et de leur complexité n’a pas été associée à une dégradation de leur utilisabilité. Enfin, dans les 6 services d’urgences participants, la majorité des patients ont bénéficié d’une ventilation mécanique à faible volume courant (entre 6 et 8 mL/kg de poids idéal théorique), répondant ainsi aux recommandations des sociétés savantes. En revanche, une ventilation à faible volume courant n’a pas été associée à une diminution de l’incidence du syndrome de détresse respiratoire aigu ou une diminution du taux de mortalité.Ces études permettent une évaluation globale du support ventilatoire aux urgences, intégrant la ventilation mécanique invasive et non-invasive, par son approche clinique et technologique, et un traitement émergent, l’OHD, par son impact clinique, gazométrique et pronostique aux urgences
Acute respiratory failure is a common complaint of patients visiting the Emergency Department and conventional oxygen therapy is its first-line treatment. Ventilatory support is required when nasal oxygen therapy is not enough or as a first-line treatment in the most severe cases. Ventilatory supports include high-flow and humidified nasal cannula oxygen (HNFO) and mechanical ventilation. Data assessing their values in Emergency Departments (EDs) mainly come from research conducted in Intensive Care Units. In addition, a comprehensive approach of their application and their results in Emergency Departments has never been conducted.The aim of this research is to provide a comprehensive assessment of ventilatory supports in EDs by assessing the place of HFNO, introducing recently in this setting, and the practice of noninvasive and invasive mechanical ventilation in EDs. We assessed first the clinical and biological impact of HFNO in patients admitting to an ED for de novo acute hypoxemic respiratory failure, then in patients admitting for acute hypercapnic respiratory failure secondary to acute heart failure, through two prospective studies. In addition, we provided a matching of data issued from all prospective trials conducted in the EDs. We aimed to determine if early application of HFNO in patients with acute respiratory failure improves outcome. We found HFNO applied early was associated with an improvement in clinical and biological patterns in patients admitted for de novo acute hypoxemic respiratory failure, and similarly in patients admitted for acute hypercapnic respiratory failure due to acute heart failure. However, HFNO was not associated with a reduction of mechanical ventilation requirements or in mortality. In addition, we assessed mechanical ventilation in the ED by analysing three determinants that may influence patient’s outcome. First, we conducted a large bench test assessing performance and usability of all emergency ventilators marketed in Europe or North America and assessing through two distinct studies. Then, we assessed the mechanical ventilation practice in six French EDs and measured the association between mechanical ventilation settings and patients’ outcome. Performance of recent emergency ventilator were closes to ICU ventilators due to high technological improvements in the last decades. These improvements were associated with an increase of their complexity without impairment of their usability. Finally, in six French EDs, most of the patients were treated with a low tidal volume (between 6 and 8 mL/kg of predicted body weight) as recommend by scientific societies. However, a low tidal volume strategy was not associated with a reduction in the acute respiratory distress incidence as well as in mortality. These studies provided a comprehensive assessment of the ventilator support in the ED, including invasive and noninvasive ventilation, through a clinical and technological approach, and an emerging treatment, HFNO, by its clinical, biological and prognostic impact
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Patout, Maxime. "Evaluation des techniques pour la prise en charge diagnostique et thérapeutique de l'insuffisance respiratoire chronique A Randomized controlled trial on the effect of needle gauge on the pain and anxiety experienced during radial arterial puncture Long term survival following initiation of home non-invasive ventilation : a European study Neural respiratory drive predicts long-term outcome following admission for exacerbation of COPD : a post hoc analysis Neural respiratory drive and cardiac function in patients with obesity hypoventilation syndrome following initiation of non-invasive ventilation Polysomnography versus limited respiratory monitoring and nurse-led titration to optimise non-invasive ventilation set-up a pilot randomised clinical trial Chronic ventilator service Step-down from non-invasive ventilation to continuous positive airway pressure : a better phenotyping is required AVAPS-AE versus ST mode : a randomized controlled trial in patients with obesity hypoventilation syndrome Technological advances in home non-invasive ventilation monitoring : reliability of data and effect on patient outcomes Efficacy of a home discharge care bundle after acute exacerbation of COPD Prediction of severe acute exacerbation using changes in breathing pattern of COPD patients on home noninvasive ventilation Charasteristics and outcome of patients set up on high-flow oxygen therapy at home Trial of portable continuous positive airway pressure for the management of tracheobronchomalacia." Thesis, Normandie, 2019. http://www.theses.fr/2019NORMR115.

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L’insuffisance respiratoire chronique est un syndrome défini par une défaillance monoviscéralerespiratoire. Sa principale origine est aujourd’hui le syndrome obésité-hypoventilation qui concerne 4 à 5% des patients obèses. L’IRC est aussi le stade évolutif terminal de la bronchopneumopathie chronique obstructive qui touche 6 à 8% de la population adulte. L’incidence de ces pathologies et donc de l’insuffisance respiratoire est en augmentation constante. Dans cette thèse, nous avons évalué les nouvelles modalités diagnostiques et thérapeutiques qui pourraient améliorer la prise en charge des patients atteints d’insuffisance respiratoire chronique.Concernant la prise en charge diagnostique, nous avons montré que les données fournies par l’électromyographie de surface des muscles intercostaux, outil qui évalue le travail respiratoire, constituent un marqueur pronostique indépendant chez les patients atteints de bronchopneumopathie chronique obstructive. Nous avons également montré leur pertinence pour prédire l’efficacité clinique et l’observance à la ventilation non-invasive à domicile.Concernant la prise en charge thérapeutique, nous avons montré que l’utilisation d’un mode semi-automatisé de ventilation non-invasive a la même efficacité que celle de modes classiques en permettant une mise en place plus rapide du traitement. Nous avons également rapporté l’intérêt de l’oxygénothérapie à haut débit au domicile alors que ce traitement était utilisé jusque-là dans le seul cadre des soins intensifs. Enfin, nous avons rapporté les bénéfices de la pression positive continue au cours de l’effort chez les patients ayant une trachéobronchomalacie. Concernant le suivi des patients, nous avons montré que les données des logiciels de ventilation non invasive permettent de prédire la survenue d’une exacerbation sévère de BPCO mais que l’utilisation de la télémédecine chez les patients insuffisants respiratoires chroniques ne peut être encore pleinement intégrée dans la pratique clinique. Au cours de cette thèse, nous avons identifié de nouveaux outils physiologiques, de nouvelles modalités d’administration des traitements et de nouveaux outils de suivi à domicile, à même d’améliorer la prise en charge des patients insuffisants respiratoires chroniques
Single-organ respiratory failure defines chronic respiratory failure. Obesity hypoventilation syndrome is the main cause of chronic respiratory failure and occurs in 4 to 5% of obese patients. Chronic respiratory failure is also the end-stage evolution of chronic obstructive pulmonary disease that has a prevalence of 6 to 8% in the adult population. The incidence of these diseases increases so does the incidence of chronic respiratory failure. In this thesis, we will evaluate novel diagnostic and therapeutic modalities that could improve the care of patients with chronic respiratory failure. Regarding diagnostic modalities, we have seen that evaluating the work of breathing with surface parasternal electromyography was an independent prognostic marker in patients with chronic obstructive pulmonary disease. We have also seen that it was a relevant tool to predict the clinicalefficacy and compliance to home non-invasive ventilation. Regarding therapeutic modalities, we have shown that the use of a semi-automatic mode of non-invasive ventilation had the same efficacy of a standard mode with a shorter length of stay for its setup. We have shown the relevance and feasibility of the use of high-flow oxygen therapy in the home setting whilst it was only used in intensive care units. Finally, we have shown the benefits of continuous positive airway pressure during exertion in patients with tracheobronchomalacia. Regarding patients’ follow-up, we have shown that the use of data from built-in software could predict the onset of a severe exacerbation of chronic obstructive pulmonary disease. However, we also show that the implementation of tele-medicine in patients with chronic respiratory failure cannot be included in daily clinical practice yet. In this thesis, we have identified novel physiological tools, novel ways to administer treatments and novel follow-up tools that can improve the management of patients with chronic respiratory failure
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Coudroy, Rémi. "Stratégies d'oxygénation non invasives dans l'insuffisance respiratoire aiguë hypoxémique des patients immunodéprimés." Thesis, Poitiers, 2019. http://www.theses.fr/2019POIT1403.

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L’insuffisance respiratoire aiguë est la première cause d’admission en Réanimation des patients immunodéprimés. Malgré les progrès thérapeutiques, leur mortalité reste très élevée en cas de recours à la ventilation mécanique invasive. La ventilation non invasive (VNI) est recommandée comme traitement de première ligne en raison de la diminution de mortalité rapportée dans les études randomisées anciennes. Récemment, ces bénéfices ont été remis en cause par des essais de plus grande ampleur. Toutefois, il est possible que les réglages de la VNI n’aient pas été optimaux dans ces études, diminuant ainsi son efficacité. Par ailleurs, l’oxygénothérapie nasale à haut débit (OHD) est une technique d’oxygénation récente avec des résultats prometteurs dans de nombreuses situations cliniques. L’objectif final de ce projet était de conduire une étude prospective randomisée multicentrique comparant la VNI avec des réglages optimisés à l’OHD chez les patients immunodéprimés admis en Réanimation pour une insuffisance respiratoire aiguë. Nous avons tout d’abord validé l’hypothèse de recherche du projet, son objectif principal, les calculs d’effectif et le taux de recrutement au moyen d’une étude pilote rétrospective. Puis nous avons élaboré le protocole de VNI à partir d’une revue systématique de la littérature comparant l’efficacité des différents protocoles de VNI publiés. Ensuite, nous avons analysé les facteurs de risque d’échec de la VNI chez les patients hypoxémiques afin d’identifier les paramètres physiologiques respiratoires à surveiller chez les patients traités par VNI. En outre, nous avons identifié les mécanismes responsables des effets physiologiques de l’OHD au moyen d’une étude sur banc puis chez des volontaires sains. Enfin, nous avons sélectionné la méthode d’estimation de la fraction inspirée en dioxygène mesurée au masque la plus fiable en comparant les différentes méthodes existantes dans le but d’affiner les critères d’inclusion du projet. Ces cinq études préliminaires nous ont permis de conduire une étude prospective randomisée dans 30 centres en France et en Italie dans le but de comparer les effets de l’OHD seule délivrée à 60 L/min à son association à la VNI intensive (administrée au moins 12 heures par jour avec une pression expiratoire positive d’au moins 8 cmH2O et un volume courant expiré inférieur à 8 ml/kg de poids prédit) sur la mortalité à 28 jours chez 300 patients immunodéprimés admis en Réanimation pour une insuffisance respiratoire aiguë
Acute respiratory failure is the leading cause of intensive care unit admission in immunocompromised patients. Despite therapeutic progresses, their mortality rate remains intolerably high when invasive mechanical ventilation is needed. Noninvasive ventilation (NIV) is currently recommended as first-line treatment in this setting given the mortality reduction reported in old randomized trials. Recently, benefits of NIV have been challenged by large sample sized trials. However, NIV settings may have been suboptimal in these studies and consequently dampened its efficacy. Moreover, high-flow nasal cannula oxygen therapy (HFOT), a more recent oxygenation technique, was associated with promising results in various clinical settings. This project aims at conducting a randomized multicenter controlled trial comparing optimized NIV with HFOT in critically ill immunocompromised patients with acute respiratory failure. First, we validated the research hypothesis, the primary outcome, the sample size calculation and the recruitment rate of the project by means of a pilot retrospective study. Then, the NIV protocol was built based on a systematic review of literature comparing the efficacy of previously published NIV protocols. Afterwards, we identified factors independently associated with NIV failure in hypoxemic patients to identify respiratory parameters to monitor during NIV. Next, we determined mechanisms leading to physiological effects of HFOT in a bench study and a study on healthy volunteers. Last, we chose the most reliable method to estimate inspired oxygen fraction under oxygen mask in a study comparing the different existing methods in order to refine inclusion criteria of the project. All in all, these five above-mentioned preliminary studies enabled to conduct a prospective multicenter randomized trial in 30 centers in France and in Italy aiming at comparing effects of HFOT alone at 60 L/min to its association with optimized NIV (applied at least 12 hours a day with a positive end-expiratory pressure of at least 8 cmH2O and an expired tidal volume lower than 8 ml/kg of predicted body weight) on mortality at day 28 in 300 immunocompromised patients admitted to the ICU for acute respiratory failure
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Tavares, Mariana Cardoso. "Terapia Nasal de Alto Fluxo." Master's thesis, 2020. http://hdl.handle.net/10316/97655.

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Trabalho Final do Mestrado Integrado em Medicina apresentado à Faculdade de Medicina
O principal objetivo do suporte respiratório é manter uma adequada ventilação e oxigenação do doente. Para atingir este objetivo, são utilizados dispositivos invasivos VI (Ventilação Invasiva) e não invasivos (VNI - Ventilação Não Invasiva; oxigenioterapia convencional) de suporte ventilatório. Com a evolução científica e tecnológica, a VI com pressão positiva rapidamente se tornou a terapêutica de eleição na insuficiência respiratória aguda grave. Esta associa-se a diversas complicações, como por exemplo o barotrauma ou volutrauma. Condiciona ainda a abolição dos mecanismos de defesa da via aérea e a necessidade de sedo-analgesia, aumentando o risco de infeção. Assim, surgiu a necessidade de explorar técnicas não invasivas de suporte ventilatório. A VNI representou um importante avanço na terapia não invasiva, e é fortemente recomendada em certas etiologias de IRA (Insuficiência Respiratória Aguda) como o edema agudo do pulmão, e de IRCA (Insuficiência Respiratória Crónica Agudizada), nomeadamente na exacerbação aguda da DPOC (Doença Pulmonar Obstrutiva Crónica) na qual é inclusivamente usada como 1ª linha terapêutica, uma vez que aumenta o Vt (Volume corrente) e mantém uma adequada ventilação alveolar. No entanto, devido à elevada taxa de intolerância à máscara (lesões cutâneas, irritação ocular e sensação de claustrofobia), a VNI é muitas vezes impossível de aplicar. Por outro lado, a oxigenioterapia convencional é a técnica mais utilizada em doentes com IRA hipoxémica. Ao longo das últimas décadas têm sido disponibilizados vários dispositivos no contexto da oxigenioterapia nos quais se incluem: sistemas de baixo fluxo (cânula nasal, máscara facial simples, máscara facial com reservatório) e de alto fluxo (máscara de Venturi). Contudo, existem diversas limitações relativas à sua aplicação que se refletem na sua eficácia e tolerância, nomeadamente: o fornecimento de uma quantidade insuficiente de oxigénio (15 L/min é geralmente o fluxo máximo administrado por máscara facial), a considerável imprecisão da FiO2 (Fração inspirada de Oxigénio) efetiva em relação à prevista (tendo em conta o fluxo inspiratório do doente e a consequente diluição do oxigénio) e ainda, a reduzida tolerabilidade quer da máscara facial, quer do oxigénio, devido ao insuficiente aquecimento e humidificação, o que gera habitualmente queixas de secura nasal e oral associada a dor. Com o intuito de ultrapassar algumas das limitações da VNI e da oxigenioterapia convencional, mas também de diminuir a utilização da VI e os seus efeitos secundários, surge a TNAF (Terapia Nasal de Alto Fluxo), uma técnica recente de suporte respiratório que tem atraído cada vez mais o interesse dos profissionais de saúde como uma alternativa potencialmente eficaz e menos deletéria na insuficiência respiratória.A Terapia Nasal de Alto Fluxo é uma recente e promissora terapia de suporte na insuficiência respiratória, que providencia um elevado fluxo de uma mistura de oxigénio/ar aquecido e humidificado. Os seus benefícios fisiológicos incluem o washout do espaço morto anatómico nasofaríngeo, a geração de uma pressão positiva faríngea, recrutamento alveolar, redução do trabalho respiratório, aumento da fração de oxigénio inspirado, manutenção da função mucociliar e ainda a capacidade de melhorar o conforto e tolerância dos doentes. Apesar de ser sobretudo aplicada como terapia de suporte respiratório em doentes com insuficiência respiratória aguda hipoxémica, recentemente, as suas indicações clínicas têm sido expandidas nomeadamente no contexto da insuficiência respiratória crónica e insuficiência respiratória crónica agudizada. Pode ainda ser usada em contexto de pós-extubação nos cuidados intensivos ou no pós-operatório, na pré e peri oxigenação durante a intubação, durante a broncoscopia, em doentes imunocomprometidos e doentes com diretivas de não intubação, e em muitos outros cenários clínicos. Há, no entanto, que conhecer as suas limitações e contraindicações para que possa ser usada com segurança e eficácia.
The main purpose of respiratory support is to maintain adequate ventilation and oxygenation of the patient. To achieve this goal, invasive devices such as IV (Invasive Ventilation) and non invasive devices such as (NIV - Non Invasive Ventilation and conventional oxygen) are used. With recent scientific and technological developments, positive-pressure IV has rapidly become the therapy of choice in severe acute respiratory failure. This is associated with various complications, such as barotrauma or volutrauma. It also conditions the abolition of airway defense mechanisms and the need for sedo-analgesia, increasing the risk of infection. Thus, the need arose to explore noninvasive ventilatory support techniques.NIV represented an important advance in noninvasive therapy, and is strongly recommended in certain etiologies of acute respiratory failure (ARF), such as acute pulmonary edema, but also in acute chronic respiratory failure (ACRF), particularly acute COPD (Chronic Obstructive Pulmonary Disease), in which it is even used as a first line support therapy, as it increases Vt (tidal volume) and maintains adequate alveolar ventilation. However, due to the high rate of mask intolerance in most patients (skin lesions, eye irritation, and feeling of claustrophobia), NIV is often impossible to apply.On the other hand, conventional oxygen therapy is the most commonly used technique in patients with hypoxemic acute respiratory failure. Over the last decades, several devices have been made available in the context of oxygen therapy, including: low flow devices (nasal cannula, simple face mask, reservoir face mask) and high flow devices (Venturi mask). However, there are several limitations regarding its application which are reflected in its efficacy and tolerance, namely: insufficient oxygen supply (15 L / min is usually the maximum flow delivered by a face mask), considerable effective FiO2 inaccuracy ( Inspired fraction of oxygen) compared to the FiO2 value that had inicially been predicted (taking into account the patient's inspiratory flow and the consequent dilution of oxygen) and also the reduced tolerability of both face mask and oxygen due to insufficient heating and humidification, which usually generates complaints of nasal and oral dryness associated with pain, leading to patients’ disconfort as well as poor adherance to this support therapy.In order to overcome some of NIV and conventional oxygen therapy limitations, but also to reduce the use of IV and its side effects, HFNT (High Flow Nasal Therapy) is emerging as a new and innovative technique of respiratory support that has attracted the interest of health care professionals as a potentially effective and less deleterious alternative in respiratory failure.High Flow Nasal Therapy is a promising novel oxygen delivery device used in respiratory failure, which provides a heated and humidified high flow of an oxygen/air mix. Its physiological benefits include nasopharyngeal dead space washout, generation of positive pressure in the pharynx, alveolar recruitment, reduced work of breathing, increased fraction of inspired oxygen, maintained mucociliar function and the ability to enhance patient’s comfort and tolerance. Although it has been mostly used as a treatment modality in patients with acute hypoxaemic respiratory failure, its clinical indications have been expanded to chronic respiratory failure and acute on chronic respiratory failure. It may also be applied to post-extubated patients in intensive care or following surgery, for pre- and peri- oxygenation during intubation, during bronchoscopy, in immunocompromised patients, in patients with “do not intubate” status and in many other clinical settings. However, it is necessary to know its limitations and contraindications so that it can be safely and effectively used.
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Books on the topic "Non-invasive ventilation therapy"

1

Christine, Mikelsons, ed. Non-invasive respiratory support techniques: Oxygen therapy, non-invasive ventilation, and CPAP. Chichester, West Sussex: Wiley-Blackwell, 2008.

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Esmond, Glenda, and Christine Mikelsons. Non-Invasive Respiratory Support Techniques: Oxygen Therapy, Non-Invasive Ventilation and CPAP. Wiley & Sons, Incorporated, John, 2009.

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Non Invasive Artificial Ventilation How When And Why. Springer Verlag, 2013.

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Spoletini, Giulia, and Nicholas S. Hill. Non-invasive positive-pressure ventilation. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0090.

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Non-invasive ventilation (NIV) has been increasingly used over the past decades to avoid endotracheal intubation (ETI) in critical care settings. In selected patients with acute respiratory failure, NIV improves the overall clinical status more rapidly than standard oxygen therapy, avoids ETI and its complications, reduces length of hospital stay, and improves survival. NIV is primarily indicated in respiratory failure due to acute exacerbations of chronic obstructive pulmonary disease, cardiogenic pulmonary oedema and associated with immunocompromised states. Weaker evidence supports its use in other forms of acute hypercapnic and hypoxaemic respiratory failure. Candidates for NIV should be carefully selected taking into consideration the risk factors for NIV failure. Patients on NIV who are unstable or have risk factors for NIV failure should be monitored in an intensive or intermediate care units by experienced personnel to avoid delay when intubation is needed. Stable NIV patients can be monitored on regular wards.
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5

Basner, Robert C., and Sairam Parthasarathy. Nocturnal Non-Invasive Ventilation: Theory, Evidence, and Clinical Practice. Springer, 2015.

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Basner, Robert C., and Sairam Parthasarathy. Nocturnal Non-Invasive Ventilation: Theory, Evidence and Best Practices. Springer, 2015.

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Basner, Robert C., and Sairam Parthasarathy. Nocturnal Non-Invasive Ventilation: Theory, Evidence, and Clinical Practice. Springer, 2016.

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Dabo, Liu. Non-Invasive Positive Pressure Ventilation for Pediatric Sleep-Disordered Breathing. Nova Science Publishers, Incorporated, 2014.

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Ramsay, Michelle, and Mike Polkey. Non-invasive ventilation and chronic obstructive pulmonary disease. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199657742.003.0012.

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Non-invasive ventilation is one of the major advances in respiratory medicine over the last century. It can be lifesaving for patients in acute hypercapnic respiratory failure, improving gas exchange and pulmonary mechanics and reducing the need for endotracheal intubation. Adherence to therapy is key to its success, and many patients find this a significant challenge. This case report will examine the pitfalls of initiating non-invasive ventilation, provide a brief overview of the current British Thoracic Society non-invasive ventilation guidelines, and describe common causes of a chronic obstructive pulmonary disease patient ‘failing’ non-invasive ventilation and an approach to the long-term management of the frequently exacerbating chronic obstructive pulmonary disease patient.
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Stacey, Victoria. Respiratory. Oxford University Press, 2013. http://dx.doi.org/10.1093/med/9780199592777.003.0010.

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Asthma - Chronic obstructive pulmonary disease (COPD) - Non-invasive ventilation - Venous thromboembolism - Pneumonia - Spontaneous pneumothorax - Respiratory failure and oxygen therapy - Arterial blood gas analysis - SAQs
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Book chapters on the topic "Non-invasive ventilation therapy"

1

Nava, Stefano, and Francesco Fanfulla. "Rationale for Ventilation Therapy During Sleep." In Non Invasive Artificial Ventilation, 177–94. Milano: Springer Milan, 2013. http://dx.doi.org/10.1007/978-88-470-5526-1_23.

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Bernabeu-Mora, Roberto. "Prognosis Following Acute Exacerbation of COPD Treated with Non-invasive Mechanical Ventilation." In Ventilatory Support and Oxygen Therapy in Elder, Palliative and End-of-Life Care Patients, 273–77. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-26664-6_31.

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Skoczyński, Szymon, and Patrycja Rzepka-Wrona. "The Role of Non-invasive Home Mechanical Ventilation in Elderly Patients with Chronic Obstructive Pulmonary Disease." In Ventilatory Support and Oxygen Therapy in Elder, Palliative and End-of-Life Care Patients, 257–63. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-26664-6_29.

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Alsunaid, Sammar R., and Ayman O. Soubani. "Acute Hypoxemic Respiratory Failure in Immunocompromised Patients: The Role of Non-invasive Ventilation and High-Flow Oxygen Therapy." In Ventilatory Support and Oxygen Therapy in Elder, Palliative and End-of-Life Care Patients, 105–14. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-26664-6_14.

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Waldmann, Carl, Andrew Rhodes, Neil Soni, and Jonathan Handy. "Respiratory therapy techniques." In Oxford Desk Reference: Critical Care, 1–54. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780198723561.003.0001.

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This chapter discusses respiratory therapy techniques and includes discussion on oxygen therapy, discussion of intermittent positive pressure ventilation and description of ventilators, modes of ventilation, adjusting the ventilator, barotrauma, and weaning techniques. The chapter also discusses high-frequency ventilation, airway pressure release ventilation, as well as positive end-respiratory pressure, continuous positive airway pressure ventilation, recruitment manoeuvres, prone position ventilation, non-invasive positive pressure ventilation, extracorporeal membrane oxygenation, cricothyroidotomy, tracheostomy, aftercare of the patient with a tracheostomy, chest drain insertion, pleural aspiration, flexible bronchoscopy, chest physiotherapy, humidification, and heart–lung interactions.
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"Acute oxygen therapy." In Non-invasive Ventilation and Weaning: Principles and Practice, 251–59. CRC Press, 2010. http://dx.doi.org/10.1201/b13434-34.

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"Acute oxygen therapy." In Non-invasive Ventilation and Weaning: Principles and Practice, 273–81. CRC Press, 2010. http://dx.doi.org/10.1201/b13434-37.

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"Equipment for oxygen therapy." In Non-invasive Ventilation and Weaning: Principles and Practice, 282–89. CRC Press, 2010. http://dx.doi.org/10.1201/b13434-38.

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Ediboglu, Ozlem. "Mechanical Ventilation for Patients with COPD." In Chronic Obstructive Pulmonary Disease - A Current Conspectus. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96633.

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Mechanical ventilation is a lifesaving therapy in patients who have acute respiratory failure due to chronic obstructive pulmonary disease (COPD). Mechanical ventilaton either invasive or non-invasive has an important role in the management of acute exacerbation of COPD (AECOPD). AECOPD required hospitalizaton had increased mortality and poor prognosis. Ventilatory management success related to understanding physiopathology of the disease. Clinicians must be aware of deterioration of clinical signs of COPD patients. The most appropriate treatment should be performed at optimal time. Some COPD patients are at high risk for prolonged mechanical ventilation due to COPD is a progressive disease.
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"Home oxygen therapy in chronic respiratory failure." In Non-invasive Ventilation and Weaning: Principles and Practice, 267–72. CRC Press, 2010. http://dx.doi.org/10.1201/b13434-36.

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Conference papers on the topic "Non-invasive ventilation therapy"

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Obeid, Imad M., Melisa A. Coaker, Luisa F. Bazan, and David W. Hudgel. "High Grade Heart Block Therapy With Non-Invasive Positive Pressure Ventilation." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a3698.

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Jaurrieta Largo, Sofia, Ignacio Lobato Astiárraga, Blanca De Vega Sánchez, María José Chourio Estaba, Ana María Andrés Porras, Ana Isabel García Onieva, Irene Alaejos Pascua, María Beatriz Cartón Sánchez, Isabel Ramos Cancelo, and Carlos Disdier Vicente. "PROGNOSTIC FACTORS FOR SUCCESSFUL ADHERENCE WITH NON-INVASIVE MECHANICAL VENTILATION THERAPY." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.pa2383.

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Giles, Brenda Louise, Cheryl Greenberg, L. Maureen Collison, and Hans Pasterkamp. "Non-Invasive Ventilation For Infants With Severe Hypophosphatasia Undergoing Enzyme Replacement Therapy." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a3120.

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Goutorbe, Philippe, Mickael Cardinale, Erwan Daranda, Olivier Castagna, Julien Bordes, Pierre Esnault, and Eric Meaudre. "In COPD, FiO2 decrease during nocturnal non-invasive ventilation compared to normobaric O2 therapy." In ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.pa3972.

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Villalobos, Ralph Elvi, Ulysses King Gopez, Karen Marie Flores, and Norman Maghuyop. "Early non-invasive ventilation versus conventional oxygen therapy in immunocompromised patients with respiratory failure: a meta-analysis." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa1889.

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Schoenheit-Kenn, U., S. Winterkamp, M. Boensch, D. Holle, and K. Kenn. "Effects of Pulmonary Rehabilitation Including Exercise Training in COPD Patients with Indication for NON-INVASIVE Ventilation Therapy (NIV)." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a1053.

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Santa Barbara, Rita de Cassia, Anselmo Costa E Silva, Leonardo Figueiroa, Ana Pascoal, Jurema Real, and Ernesto Antonio. "Non-invasive ventilation as a first-line treatment for malaria patients with pulmonary dysfunction: A feature of respiratory therapy." In ERS International Congress 2018 abstracts. European Respiratory Society, 2018. http://dx.doi.org/10.1183/13993003.congress-2018.pa2404.

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Cuerpo Carde?osa, S., J. R. Francesqui Candela, F. Hernandez-Gonzalez, M. Palomo, I. Blanco, C. Embid, and J. Sellares Torres. "Improving Home Oxygen Therapy in Patients with Interstitial Lung Diseases (ILDS): Application of a Portable Non-Invasive Ventilation (NIV) Device." In American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a1515.

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Cuerpo, Sandra, Joel Francesqui, Fernanda Hernandez, Maria Palomo, Carmen Hernandez, Isabel Blanco, Cristina Embid, and Jacobo Sellares. "Improving home oxigen therapy in patients with interstitial lung diseases (ILDs): Application of a portable non-invasive ventilation (NIV) device." In ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.pa1722.

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Turgut, B., I. Naz, and C. Kıraklı. "Comparison of Sitting Balance and Functional Independence Levels of COPD Patients Receiving and Not Receiving Non-Invasive Mechanical Ventilation Therapy." In ERS International Congress 2022 abstracts. European Respiratory Society, 2022. http://dx.doi.org/10.1183/13993003.congress-2022.1667.

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Reports on the topic "Non-invasive ventilation therapy"

1

Sanguanwong, Natthawan, Nattawat Jantarangsi, Natthida Owattanapanich, and Vorakamol Phoophiboon. Effect of non-invasive ventilation and high flow nasal cannula on interstitial lung disease with acute respiratory failure: A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2022. http://dx.doi.org/10.37766/inplasy2022.6.0104.

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Review question / Objective: P: Interstitial lung disease patient who is suffering with acute respiratory failure. I: Non-invasive oxygen therapy either non-invasive ventilation (NIV) or high flow nasal cannula (HFNC). C: 1. Conventional oxygen therapy, 2. NIV vs HFNC. O: P/F ratio improvement, PaCO2 reduction, mortality, intubation rate. Condition being studied: The benefit of using either non-invasive ventilation or high flow nasal cannula on interstitial lung disease with acute respiratory failure.
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