Relevant bibliographies by topics / Non-enzymatic glucose sensing

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Academic literature on the topic 'Non-enzymatic glucose sensing'

Author: Grafiati
Published: 6 September 2023

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Journal articles on the topic "Non-enzymatic glucose sensing"

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Wang, Guangfeng, Xiuping He, Lingling Wang, Aixia Gu, Yan Huang, Bin Fang, Baoyou Geng, and Xiaojun Zhang. "Non-enzymatic electrochemical sensing of glucose." Microchimica Acta 180, no. 3-4 (December 21, 2012): 161–86. http://dx.doi.org/10.1007/s00604-012-0923-1.

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Hassan, Mohamed H., Cian Vyas, Bruce Grieve, and Paulo Bartolo. "Recent Advances in Enzymatic and Non-Enzymatic Electrochemical Glucose Sensing." Sensors 21, no. 14 (July 8, 2021): 4672. http://dx.doi.org/10.3390/s21144672.

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The detection of glucose is crucial in the management of diabetes and other medical conditions but also crucial in a wide range of industries such as food and beverages. The development of glucose sensors in the past century has allowed diabetic patients to effectively manage their disease and has saved lives. First-generation glucose sensors have considerable limitations in sensitivity and selectivity which has spurred the development of more advanced approaches for both the medical and industrial sectors. The wide range of application areas has resulted in a range of materials and fabrication techniques to produce novel glucose sensors that have higher sensitivity and selectivity, lower cost, and are simpler to use. A major focus has been on the development of enzymatic electrochemical sensors, typically using glucose oxidase. However, non-enzymatic approaches using direct electrochemistry of glucose on noble metals are now a viable approach in glucose biosensor design. This review discusses the mechanisms of electrochemical glucose sensing with a focus on the different generations of enzymatic-based sensors, their recent advances, and provides an overview of the next generation of non-enzymatic sensors. Advancements in manufacturing techniques and materials are key in propelling the field of glucose sensing, however, significant limitations remain which are highlighted in this review and requires addressing to obtain a more stable, sensitive, selective, cost efficient, and real-time glucose sensor.
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Tee, Si Yin, Choon Peng Teng, and Enyi Ye. "Metal nanostructures for non-enzymatic glucose sensing." Materials Science and Engineering: C 70 (January 2017): 1018–30. http://dx.doi.org/10.1016/j.msec.2016.04.009.

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Thatikayala, Dayakar, Deepalekshmi Ponnamma, Kishor Sadasivuni, John-John Cabibihan, Abdulaziz Al-Ali, Rayaz Malik, and Booki Min. "Progress of Advanced Nanomaterials in the Non-Enzymatic Electrochemical Sensing of Glucose and H2O2." Biosensors 10, no. 11 (October 22, 2020): 151. http://dx.doi.org/10.3390/bios10110151.

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Non-enzymatic sensing has been in the research limelight, and most sensors based on nanomaterials are designed to detect single analytes. The simultaneous detection of analytes that together exist in biological organisms necessitates the development of effective and efficient non-enzymatic electrodes in sensing. In this regard, the development of sensing elements for detecting glucose and hydrogen peroxide (H2O2) is significant. Non-enzymatic sensing is more economical and has a longer lifetime than enzymatic electrochemical sensing, but it has several drawbacks, such as high working potential, slow electrode kinetics, poisoning from intermediate species and weak sensing parameters. We comprehensively review the recent developments in non-enzymatic glucose and H2O2 (NEGH) sensing by focusing mainly on the sensing performance, electro catalytic mechanism, morphology and design of electrode materials. Various types of nanomaterials with metal/metal oxides and hybrid metallic nanocomposites are discussed. A comparison of glucose and H2O2 sensing parameters using the same electrode materials is outlined to predict the efficient sensing performance of advanced nanomaterials. Recent innovative approaches to improve the NEGH sensitivity, selectivity and stability in real-time applications are critically discussed, which have not been sufficiently addressed in the previous reviews. Finally, the challenges, future trends, and prospects associated with advanced nanomaterials for NEGH sensing are considered. We believe this article will help to understand the selection of advanced materials for dual/multi non-enzymatic sensing issues and will also be beneficial for researchers to make breakthrough progress in the area of non-enzymatic sensing of dual/multi biomolecules.
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Mahmoud, Amira, Mosaab Echabaane, Karim Omri, Julien Boudon, Lucien Saviot, Nadine Millot, and Rafik Ben Chaabane. "Cu-Doped ZnO Nanoparticles for Non-Enzymatic Glucose Sensing." Molecules 26, no. 4 (February 10, 2021): 929. http://dx.doi.org/10.3390/molecules26040929.

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Copper-doped zinc oxide nanoparticles (NPs) CuxZn1−xO (x = 0, 0.01, 0.02, 0.03, and 0.04) were synthesized via a sol-gel process and used as an active electrode material to fabricate a non-enzymatic electrochemical sensor for the detection of glucose. Their structure, composition, and chemical properties were characterized using X-ray diffraction (XRD), transmission electron microscopy (TEM), Fourier-transform infrared (FTIR) and Raman spectroscopies, and zeta potential measurements. The electrochemical characterization of the sensors was studied using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and differential pulse voltammetry (DPV). Cu doping was shown to improve the electrocatalytic activity for the oxidation of glucose, which resulted from the accelerated electron transfer and greatly improved electrochemical conductivity. The experimental conditions for the detection of glucose were optimized: a linear dependence between the glucose concentration and current intensity was established in the range from 1 nM to 100 μM with a limit of detection of 0.7 nM. The proposed sensor exhibited high selectivity for glucose in the presence of various interfering species. The developed sensor was also successfully tested for the detection of glucose in human serum samples.
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Luo, Xi, Zijun Zhang, Qijin Wan, Kangbing Wu, and Nianjun Yang. "Lithium-doped NiO nanofibers for non-enzymatic glucose sensing." Electrochemistry Communications 61 (December 2015): 89–92. http://dx.doi.org/10.1016/j.elecom.2015.10.005.

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Sun, Feng-chao, Jing-tong Zhang, Hao Ren, Shu-tao Wang, Yan Zhou, and Jun Zhang. "“Dry” NiCo2O4 nanorods for electrochemical non-enzymatic glucose sensing." Chinese Journal of Chemical Physics 31, no. 6 (December 2018): 799–805. http://dx.doi.org/10.1063/1674-0068/31/cjcp1804061.

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Chiu, Wan-Ting, Tso-Fu Mark Chang, Masato Sone, Hideki Hosoda, Agnès Tixier-Mita, and Hiroshi Toshiyoshi. "Developments of the Electroactive Materials for Non-Enzymatic Glucose Sensing and Their Mechanisms." Electrochem 2, no. 2 (June 21, 2021): 347–89. http://dx.doi.org/10.3390/electrochem2020025.

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A comprehensive review of the electroactive materials for non-enzymatic glucose sensing and sensing devices has been performed in this work. A general introduction for glucose sensing, a facile electrochemical technique for glucose detection, and explanations of fundamental mechanisms for the electro-oxidation of glucose via the electrochemical technique are conducted. The glucose sensing materials are classified into five major systems: (1) mono-metallic materials, (2) bi-metallic materials, (3) metallic-oxide compounds, (4) metallic-hydroxide materials, and (5) metal-metal derivatives. The performances of various systems within this decade have been compared and explained in terms of sensitivity, linear regime, the limit of detection (LOD), and detection potentials. Some promising materials and practicable methodologies for the further developments of glucose sensors have been proposed. Firstly, the atomic deposition of alloys is expected to enhance the selectivity, which is considered to be lacking in non-enzymatic glucose sensing. Secondly, by using the modification of the hydrophilicity of the metallic-oxides, a promoted current response from the electro-oxidation of glucose is expected. Lastly, by taking the advantage of the redistribution phenomenon of the oxide particles, the usage of the noble metals is foreseen to be reduced.
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Wei, Ming, Yanxia Qiao, Haitao Zhao, Jie Liang, Tingshuai Li, Yonglan Luo, Siyu Lu, Xifeng Shi, Wenbo Lu, and Xuping Sun. "Electrochemical non-enzymatic glucose sensors: recent progress and perspectives." Chemical Communications 56, no. 93 (2020): 14553–69. http://dx.doi.org/10.1039/d0cc05650b.

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This review summarizes recent advances in the development of electrocatalysts for non-enzymatic glucose detection. The sensing mechanism and influencing factors are discussed, and the perspectives and challenges are also addressed.
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Lin, Yu-Hsuan, Chandrasekar Sivakumar, Babu Balraj, Gowtham Murugesan, Senthil Kumar Nagarajan, and Mon-Shu Ho. "Ag-Decorated Vertically Aligned ZnO Nanorods for Non-Enzymatic Glucose Sensor Applications." Nanomaterials 13, no. 4 (February 17, 2023): 754. http://dx.doi.org/10.3390/nano13040754.

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The non-enzymatic glucose sensing response of pure and Ag-decorated vertically aligned ZnO nanorods grown on Si substrates was investigated. The simple low-temperature hydrothermal method was employed to synthesize the ZnO NRs on the Si substrates, and then Ag decoration was achieved by sputtering. The crystal structure and surface morphologies were characterized by X-ray diffraction, field-emission scanning electron microscopy (FESEM), and transmission electron microscopy (TEM). The Ag incorporation on the ZnO NR surfaces was confirmed using EDS mapping and spectra. Furthermore, the chemical states, the variation in oxygen vacancies, and the surface modifications of Ag@ZnO were investigated by XPS analysis. Both the glucose/ZnO/Si and glucose/Ag@ZnO/Si device structures were investigated for their non-enzymatic glucose sensing performances with different glucose concentrations. Based on EIS measurements and amperometric analysis, the Ag@ZnO-NR-based glucose sensor device exhibited a better sensing ability with excellent stability over time than pure ZnO NRs. The Ag@ZnO NR glucose sensor device recorded 2792 µA/(mM·cm2) sensitivity with a lowest detection limit of 1.29 µM.
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Dissertations / Theses on the topic "Non-enzymatic glucose sensing"

1

Yi-ShuHsieh and 謝宜澍. "Fabrication of Ni-Au Alloy Nanowire Glucose Sensor for Non-enzymatic Glucose Sensing." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/auy526.

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碩士
國立成功大學
微電子工程研究所
107
In this research, the fabrication of Ni-Au alloy nanowire for non-enzymatic glucose sensor on p-silicon based anodic aluminum oxide (AAO) template is discussed. The Ni-Au alloy nanowire is applied on an electrochemical glucose sensor. The Ni-Au alloy nanowire was fabricated via the self-made AAO template grown on the p-type heavily doped silicon substrate. The advantages of AAO on silicon are lower cost, stronger mechanical and less production time consuming comparing to traditional AAO grown directly by using aluminum. The electrodeposition of the Ni-Au alloy nanowire was fabricated by three-electrode system and pulse signals. The best parameter of Ni-Au alloy nanowire electrodeposition is (-1.6)V、PH2.0 and duty cycle 10%. To remove the AAO template after depositing, 2M alkaline medium was used in 30℃. The Ni-Au alloy nanowires exhibit high uniform arrangement. Further, use the Ni-Au alloy nanowires for the application of glucose measurement. After a successive injection of glucose and other substantial for measurement, the Ni-Au alloy glucose sensor exhibited a linear range of 0-3mM, a sensitivity of 1893 μA/mMcm2, and a detection limit of 1μM. Simultaneously, a superior selectivity and at least 30 days stability was also observed. The characteristics show that Ni-Au alloy nanowire has an excellent performance for glucose sensing.
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Fan, Hsin-Hsin, and 范馨心. "Flower-like Cu/CuxO Nanowire Array Electrodes for Non-enzymatic Glucose Sensing." Thesis, 2018. http://ndltd.ncl.edu.tw/handle/2s292r.

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Lin, Hsiang-Ying, and 林湘瑩. "Application of a nanoporous gold electrode with the highly morphological recoverability for non-enzymatic glucose sensing." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/14967491699808401953.

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碩士
國立中興大學
化學系所
99
In this study, an enzyme-free glucose sensor has been developed by using a nanoporous gold (NPG) electrode. The intrinsic ultra-high surface area also substantially enhances the sensitivity. Cyclic voltammetry (CV) and amperometric detection are used to investigate the electrochemical behavior of glucose. The long-term storability and the stability of the electrode are strongly demonstrated. Specifically, The CV of glucose on the NPG shows that the initial oxidation of glucose starts at -0.9V. The potential is more negative than -0.4 V on a smooth Au (SAu). The interested potential negative shift is related to the unique nano-structure on the NPG. The interferences from some common interfering species, such as ascorbic acid (AA), uric acid (UA), and p-acetaminophen (AP), are also successfully inhibited due to the intrinsic ultra-high surface area of NPG. The calibration curve shows a linear dependence in the glucose concentration range of 0.01–10.0 mM with an extra high sensitivity of 3769.6 µAmM−1 cm−2. The detection limit is 0.71 µM (signal-to-noise ratio of 3).
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WANG, PEI-LUN, and 王珮倫. "A Simple Impregnation to Prepare CuO/XC72 Composites And Their Performances in Non-enzymatic Glucose Sensing." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/97253148184213047207.

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碩士
國立臺南大學
材料科學系碩士班
105
Copper oxides have been synthesized on a conductive carbon black (XC72) to form the CuO/XC72 composites using a simple impregnation. In the glucose sensing, 30 wt% CuO/XC72 displays better performances than those of other samples. The sensitivity of 30 wt% CuO/XC72 is 1680.2 μAmM-1cm-2. The limit of detection (LOD) and linear range are 1 μM and 1 μM-3.26 mM. The glucose sensor based on the 30 wt% CuO/XC72 composites show the fast response time (< 3 sec), reproducibility and good selectivity.
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Wang, Zi-Ming, and 王子銘. "Study of Surfactantless Self-Assembled CuO Sphere Structures and Composited with MnO2 Nanorods for Non-enzymatic Glucose Sensing Applications." Thesis, 2019. http://ndltd.ncl.edu.tw/handle/2yka74.

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碩士
國立中山大學
電機工程學系研究所
107
In this study, we investigated the sphere structures of copper oxide (CuO) and composited with manganese dioxide (MnO2) nanorods on ITO/glass substrate for non-enzymatic glucose (C6H12O6) sensors. Firstly, CuO seed layer was deposited by RF sputtering system on ITO/glass substrate. After the CuO spheres synthesized by hydrothermal method, the material was composited with MnO2. We discussed the influence of the nanostructures of different morphologies on the catalytic ability to glucose. The CuO nanospheres were synthesized under different concentrations of ammonia with cupric acetate and cupric nitrate, respectively. These spheres were self-assembled without surfactant. According to the results, the sample of CuO spheres fabricated with cupric nitrate powder and 5 mL ammonia has the best sensing capability. After it composited with MnO2 nanorods, the sensitivity is 2360.81 μAmM-1cm-2. Besides, the linear sensing range is 0.5-2.5mM (R2 = 0.9988). The superiority of the device is that the CuO spheres have more pores and reaction sites to react with glucose. Furthermore, the current variation of the device is small while adding interferents during measurement. Excellent glucose sensors can detect diabetes more accurately and quickly. They are also important in the development of food industry.
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Kumar, Sushant. "Translation from batch to continuous processing of metal nanoparticle synthesis and application metallic nanostructures printed on flexible substrates." Thesis, 2021. https://etd.iisc.ac.in/handle/2005/5810.

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One of the key challenges in nanoparticle synthesis is the quality control on scaling up the operation from bench to plant scale, which is constrained by conventionally adopted batch operation. Translation from batch operation to continuous green synthesis (metal, bi-metallic core-shell, and alloy nanoparticles (NPs)) with low polydispersity index (PDI) could unlock potential applications of metallic nanostructures with a projected market of $40.6 Billion and more by 20271. However, the continuous large-scale production suffers from high polydispersity due to lack of process optimization. We attempt to address such scale-up challenges while using the green synthesis of metallic nanoparticles in this work. The objective of this thesis is to optimize continuous processing of metal nanoparticle synthesis and demonstrate application of metallic nanostructure printed of flexible substrate using inkjet printing technology. The first part of the thesis is motivated by the desire to translate the batch protocol for NPs synthesis (developed in our group earlier)2,3 to a continuous process, and hence increase the affordability of NPs for end users. In this work, nanoparticle colloids are synthesized using different designs of CFRs and steady-state synthesis of nanoparticles is achieved with insignificant variation in particle size. Our results further showed that a balance between engineering and chemical parameters are required to obtain desired particle size distribution (PSD) and morphology during green synthesis of NPs. We improved our reactor design from channel to pool-based to address poor reagent mixing and our results show that the pool reactors could produce uniform particles of sizeii 7.2±1.0 nm with the production rate of 7.1 mg/h. We later moved to a CSTR-based reactor to address variations in the particles’ morphology while changing the flow rate of precursor salt. We found that the CSTR-based reactor can synthesise colloids (Gold, Silver, bimetallic gold-silver core-shell, and gold-silver alloy) at higher (10 times) flow rates and offers a better and affordable route for continuous nanoparticles synthesis within numerous applications in the healthcare and energy sectors. For the first time, to the best of my knowledge, the steady-state synthesis of metal nanoparticles is demonstrated here. After attaining steady state, the particle size distribution does not vary significantly. Investigations are performed to find out the effect of engineering parameters as well as chemical parameters. Particle size distribution is more sensitive to chemical parameters in comparison to engineering parameters. Although, engineering parameters like reactor design, mixing, temperature are important parameters to tailor nanoparticle size in a controlled fashion. Hence, there must be a balance between both to get desired particle size and morphology. In the second part of the thesis, we demonstrated the application of in-situ fabricated silver nanowires on copier paper for non-enzymatic glucose, using a form of inkjet printing technology. The inkjet printing technique is another avenue of fabrication of nanostructure-based flexible substrates that can be scaled using roll to roll printing techniques. Using this technique, we could fabricate, and customize electroadhesive pads based on interdigitated electrode designs with an interelectrode distance of 1 mm on paper. It was observed that, if left as a residue, lateral silver ion migration on applying high voltage leads to lowering of the gaps between electrodes, which resultsiii in increased load capacity. Further electromigration can be controlled by chemical fixing of the sample, i.e., by immersing printed samples in 0.5 M Sodium thiosulphate. The advantage of this process is that different designs of electrodes can be easily fabricated depending upon the required application. The in-situ fabricated silver nanowires incorporated with CuO/Cu2O nanoparticles are used for non-enzymatic glucose detection. Non-enzymatic sensors (4th generation) can replace the enzymatic detectors (3rd generation)4, but major challenge associated with 4th generation detectors is that it requires alkaline pH for reaction to be initiated. Paper based standard electrode (Ag/AgCl); silver nanowire incorporated with CuO/Cu2O nanoparticles (synthesised by wet chemical method) are used as working electrode. Ag nanowires modified with CuO nanoparticles show a linear increment in current with increase in glucose concentration. Glucose detection is performed in the concentration range of normal sugar level in human body in the range from 2.2 – 6.6 mM.iv References: 1 Metal Nanoparticles - Global Market Trajectory & Analytics 2021, (19/09/2021). 2 Sivaraman, S. K., Kumar, S. Santhanam, V. Room-temperature synthesis of gold nanoparticles; Size-control by slow addition. Gold Bulletin 43, 275-286 (2010). 3 Sivaraman, S. K., Kumar, S. Santhanam, V. Monodisperse sub-10nm gold nanoparticles by reversing the order of addition in Turkevich method – The role of chloroauric acid. Journal of Colloid and Interface Science 361, 543-547 (2011). 4 Toghill, K. E. & Compton, R. G. Electrochemical non-enzymatic glucose sensors: a perspective and an evaluation. Int. J. Electrochem. Sci 5, 1246-1301 (2010).
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Conference papers on the topic "Non-enzymatic glucose sensing"

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Hsu, Che-Wei, Fang-Ci Su, Po-Yu Peng, Hong-Tsu Young, Mike Yang, and Gou-Jen Wang. "A Novel Non-Enzymatic Electrochemical Glucose Biosensor Based on a Simple Lithographic Process." In ASME 2015 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/detc2015-46954.

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Diabetes is a severe public health problem globally. There are about 387 million people worldwide suffer from this medical condition. Regular detection of a diabetes patient’s blood glucose is essential to maintain the blood sugar level. In this study, a novel non-enzyme glucose biosensor based on a simple lithographic process is proposed. Photoresist AZ-1518 is spinning-coated on a silicon wafer. Exposure and development using a mask with hexagonal close-packed circle array is than conducted to generate a hexagonal close-packed column array of the AZ-1518. The diameter of each circle is set as 4 μm. A thermal melting process is than employed to convert each photoresist column into a photoresist hemisphere. Finally, a gold thin film is then sputtered onto the hemisphere array of AZ-1518 to form the sensing electrode. The sensing area is measured to be enhanced by 8.8 folds. Actual glucose detections demonstrated that the proposed simple non-enzyme glucose biosensor can operate in a linear range of 2.8 mM–27.8 mM and a sensitivity of 18.7 μA mM−1cm−2. A detection limit of 9 μM (S/N = 3) was measured. The proposed novel glucose biosensor possesses advantages of enzyme free, simple fabrication process, low cost, and easy to long-term preservation. It is feasible for future clinical applications.
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Naikoo, Gowhar Ahmad, and Mehrai Ud Din Sheikh. "Development of Highly Efficient NiO based Composite Materials for Ultra-Sensitive Glucose Sensors Non Enzymatic Glucose Sensors." In 2019 13th International Conference on Sensing Technology (ICST). IEEE, 2019. http://dx.doi.org/10.1109/icst46873.2019.9047722.

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More, Kiran D., Jagdish W. Dadge, Rajendra S. Khairnar, and Kashinath A. Bogle. "Development of nano-TiO2/Al electrode for non-enzymatic glucose bio-sensing application." In 3RD INTERNATIONAL CONFERENCE ON CONDENSED MATTER AND APPLIED PHYSICS (ICC-2019). AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0001669.

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Zhao, Jingjing, Shaohua Lu, Shuting Fan, and Zhengfang Qian. "Enhanced THz signal via Au encapsulated in hydrogel gel for non-enzymatic glucose sensing." In 2021 46th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz). IEEE, 2021. http://dx.doi.org/10.1109/irmmw-thz50926.2021.9567598.

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Olejnik, Adrian, Katarzyna Siuzdak, Anna Dołęga, Jakub Karczewski, and Katarzyna Grochowska. "Non-enzymatic glucose sensing Au-Ti platform covered with photopolymerized poly(zwitterionic) coating with enhanced selectivity and durability in human serum." In The 1st International Electronic Conference on Biosensors. Basel, Switzerland: MDPI, 2020. http://dx.doi.org/10.3390/iecb2020-07048.

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