Relevant bibliographies by topics / Nitric oxide synthase

Academic literature on the topic 'Nitric oxide synthase'

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Published: 4 June 2021
Last updated: 20 February 2023

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Journal articles on the topic "Nitric oxide synthase"

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Kim, Youngsun, Donghee Choi, Hosun Jang, Changsu Na, Moonhyeon Hwang, Joohyun Cho, Kyoungin Lee, Sunmin Kim, Byoungsik Pyo, and Daehwan Youn. "Effects of Acupuncture at ST41, BL60, GB38 on Changes of Nitric Oxide and Nitric Oxide Synthase in Rats." Korean Journal of Acupuncture 30, no. 2 (June 27, 2013): 97–103. http://dx.doi.org/10.14406/acu.2013.30.2.097.

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Ma, Li, and John L. Wallace. "Endothelial nitric oxide synthase modulates gastric ulcer healing in rats." American Journal of Physiology-Gastrointestinal and Liver Physiology 279, no. 2 (August 1, 2000): G341—G346. http://dx.doi.org/10.1152/ajpgi.2000.279.2.g341.

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Nitric oxide has been shown to be beneficial for gastric ulcer healing. We determined the relative effects of endothelial and inducible nitric oxide synthases on gastric ulcer healing in rats. Ulcers were induced by serosal application of acetic acid. Ulcer severity, angiogenesis, and nitric oxide synthase expression were assessed 3–10 days later. The effects of inhibitors of nitric oxide synthase were also examined. Inducible nitric oxide synthase mRNA was only detected in ulcerated tissue (maximal at day 3), whereas the endothelial isoform mRNA was detected in normal tissue and increased during ulcer healing. Inducible nitric oxide synthase was expressed in inflammatory cells in the ulcer bed, whereas endothelial nitric oxide synthase was found in the vascular endothelium and in some mucosal cells in both normal and ulcerated tissues. Angiogenesis changed in parallel with endothelial nitric oxide synthase expression. N 6-(iminoethyl)-l-lysine did not affect angiogenesis or ulcer healing, while N G-nitro-l-arginine methyl ester significantly reduced both. In conclusion, endothelial nitric oxide synthase, but not the inducible isoform, plays a significant role in gastric ulcer healing.
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Yui, Yoshiki. "Nitric Oxide Synthase." Japanese Journal of Pharmacology 58 (1992): 17. http://dx.doi.org/10.1016/s0021-5198(19)37713-3.

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Han, Ji young, Younghwa Kim, Jeehye Sung, Yurry Um, Yi Lee, and Junsoo Lee. "Suppressive Effects of Chrysanthemum zawadskii var. latilobum Flower Extracts on Nitric Oxide Production and Inducible Nitric Oxide Synthase Expression." Journal of the Korean Society of Food Science and Nutrition 38, no. 12 (December 31, 2009): 1685–90. http://dx.doi.org/10.3746/jkfn.2009.38.12.1685.

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Kim, Ji-Soo, Hee-Jin Ahn, Hwa-Jeong Shin, Gyo-Jeong Gu, Sang-Hoon Eum, Chung-Ho Lee, In-Soon Min, and Hyung-Sun Youn. "Curcumin Inhibits Ovalbumin-Induced Inducible Nitric Oxide Synthase Expression." Korean Journal of Food Science and Technology 44, no. 4 (August 31, 2012): 498–501. http://dx.doi.org/10.9721/kjfst.2012.44.4.498.

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Lee, A.-Neum, Se-Jeong Park, Ae-Ri Jeong, Jae-Ran Lee, Hye-Jeong Park, Soo-Jung Kim, In-Soon Min, and Hyung-Sun Youn. "Ovalbumin Induces Cyclooxygenase-2 and Inducible Nitric Oxide Synthase Expression." Korean Journal of Food Science and Technology 43, no. 1 (February 28, 2011): 110–13. http://dx.doi.org/10.9721/kjfst.2011.43.1.110.

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Галкін, Б. М., В. О. Iваниця, and М. Б. Галкін. "BACTERIAL NITRIC OXIDE SYNTHASE." Microbiology&Biotechnology, no. 3(15) (September 15, 2011): 6–22. http://dx.doi.org/10.18524/2307-4663.2011.3(15).92878.

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Resink, Annelies, Valina L. Dawson, and Ted M. Dawson. "Nitric Oxide Synthase Inhibitors." CNS Drugs 6, no. 5 (November 1996): 351–57. http://dx.doi.org/10.2165/00023210-199606050-00002.

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Ghafourifar, Pedram. "Mitochondrial nitric oxide synthase." Frontiers in Bioscience 12, no. 1 (2007): 1072. http://dx.doi.org/10.2741/2127.

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Mulrennan, Siobhan A., and Anthony E. Redington. "Nitric Oxide Synthase Inhibition." Treatments in Respiratory Medicine 3, no. 2 (2004): 79–88. http://dx.doi.org/10.2165/00151829-200403020-00002.

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Dissertations / Theses on the topic "Nitric oxide synthase"

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Nguyen, Yen Hoang Le Dervan Peter B. Gray Harry B. "Wiring inducible nitric oxide synthase /." Diss., Pasadena, Calif. : California Institute of Technology, 2007. http://resolver.caltech.edu/CaltechETD:etd-09262006-134259.

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Fairley, Brian. "Porphyrin models for nitric oxide synthase." Thesis, Heriot-Watt University, 2001. http://hdl.handle.net/10399/534.

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Pluciennick, Cecile. "Biomimetic models for nitric oxide synthase." Thesis, Heriot-Watt University, 2002. http://hdl.handle.net/10399/439.

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Feng, Gui-jie. "Regulation of inducible nitric oxide synthase." Thesis, University of Glasgow, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.360104.

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Wei, Xiao-qing. "Inducible nitric oxide synthase gene targeting." Thesis, University of Glasgow, 1995. http://theses.gla.ac.uk/8351/.

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Nitric oxide (NO) is a critical mediator of a variety of biological functions, including vascular and muscle relaxation, platelet aggregation, neuronal-cell function, microbicidal and tumoricidal activity, and a range of immunopathologies. NO is derived from L-arginine and molecular oxygen in a reaction catalysed by NO synthase (NOS). Three isoforms of NOS have been identified; neuronal constitutive NOS (ncNOS), endothelial constitutive NOS (ecNOS), and inducible NOS (iNOS). ncNOS and ecNOS are calcium-dependent, present constitutively in a variety of tissues and produce physiological concentrations of NO. However, large amounts NO are produced by iNOS which are expressed in cells such as macrophage after stimulation with a number of cytokines, including interferon-gamma (IFN-γ), tumour necrosis factor-alpha (TNF-α), and bacterial lipopolysaccharide (LPS). Findings of iNOS biological functions are based mainly on experiments using L-arginine analogues such as L-NG monomethyl arginine (L-NMMA) which competitively inhibits NO Synthase. These inhibitors are not NOS isoform selective and have differential bioavailability, and hence often render interpretation of results difficult. To directly define the iNOS biological functions, I constructed a strain of iNOS gene targeted mice. The first step of a gene targeting experiment is typically cDNA cloning and sequencing. A cDNA library was constructed in the vector λ ZAPII using mRNA isolated from J774 macrophages activated with IFN-? and LPS. Six independent positive colonies were found in the screen with both 5' and 3' specific probes and were subcloned in pBluescript. A full-length iNOS cDNA was constructed using the clones isolated from the library. Double strand cDNA sequence analysis showed that the J774 iNOS clone was identical to that of the Raw 264.7 macrophages iNOS cDNA sequence. A replacement-type targeting construct was prepared from 129/sv genomic DNA. A single targeted clone was identified amongst 636 screened after two independent electroporations of the CGR8 embryonic stem cell line. Gene replacement was detected by both 5' and 3' specific external probes. Five of ten chimeras generated gave germ line transmission. No homozygous mice were found by Southern blot analysis with 5' and 3' external probe in the offspring from heterozygous mice (FI) breedings. The iNOS gene had been altered by replacement with gene targeting construct and 5' iNOS gene translocation which could be detected by internal probe Southern blot analysis. Using the internal probe, mutant homozygous, heterozygous and wild-type mice were found in the offspring from heterozygous breedings. The ratio of these three genotypes was 21:47:25. Northern blot analysis with 5' iNOS cDNA probe showed that a large messenger appeared in the macrophages of homozygous mice when the cells were activated with IFN-γ and LPS in vitro. However there was no detectable iNOS protein translation by western blot analysis using monoclonal or polyclonal anti-iNOS antibodies.
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Lahiri, Mayurika. "Characterisation of nitric oxide synthase isoforms and nitric oxide synthase activity in human breast cancer cell lines." Thesis, University of Wolverhampton, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391489.

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Molinari, Micol Ariella. "Nitric oxide synthase and the contribution of nitric oxide to vertebrate motor contol /." St Andrews, 2008. http://hdl.handle.net/10023/489.

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Åkesson, Björn. "Islet constitutive nitric oxide synthase and nitric oxide production modulatory effects on insulin and glucagon secretion /." Diss., Lund, Sweden : Dept. of Pharmacology, University of Lund, 1998. http://catalog.hathitrust.org/api/volumes/oclc/41383563.html.

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Lane, Paul B. "Molecular regulation of endothelial nitric oxide synthase." Thesis, University of Surrey, 2000. http://epubs.surrey.ac.uk/848628/.

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The three isoforms of nitric oxide synthase (NOS) are classified based on their mode of regulation by calmodulin (CaM). The "calcium-independent" inducible isoform (iNOS) contains tightly-bound CaM and is active at all levels of intracellular calcium. In contrast, the two calcium-dependent isoforms (neuronal, nNOS and endothelial eNOS) are activated by CaM-binding following stimulus-evoked increases in intracellular calcium. However, both the structural basis for these differences in regulation and the molecular basis for CaM-induced cNOS activation remained unclear. Given that the regulation of calmodulin regulated enzyme systems often involves the displacement of an intrinsic autoinhibitory domain, we attempted to identify regions of eNOS which may fulfill this autoinhibory function. Herein, I describe the identification of two autoinhibitory control elements (ACEs) in eNOS, one within the FMN binding domain (ACE-I) and one located at the C-terminus (ACE-2). Together with CaM, these form a tripartite system for the regulation of eNOS. ACE-lIACE-2 exerting negative effects to attenuate catalytic activity, which are overcome by the conformational changes induced by CaM-binding. The mechanism of ACE-lIACE-2-mediated inhibition and the alleviation of this inhibition were investigated.
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Wang, Tingting. "Molecular Regulation of Inducible Nitric Oxide Synthase." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1353684453.

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Books on the topic "Nitric oxide synthase"

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Aviv, Hassid, ed. Nitric oxide protocols. 2nd ed. Totowa, N.J: Humana Press, 2004.

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service), ScienceDirect (Online, ed. Nitric oxide. San Diego, Calif: Elsevier/Academic Press, 2008.

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C, Fang Ferric, ed. Nitric oxide and infection. New York: Kluwer Academic/Plenum Publishers, 1999.

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Lahiri, Mayurika. Characterisation of nitric oxide synthase isoforms and nitric oxide synthase activity in human breast cancer cell lines. Wolverhampton: University of Wolverhampton, 2001.

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Åkesson, Björn. Islet constitutive nitric oxide synthase and nitric oxide production: Modulatory effects on insulin and glucagon secretion. Lund, Sweden: Dept. of Pharmacology, University of Lund, 1998.

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Giménez, Maria Sofia. Advances in chemistry and biology of nitric oxide. Kerala, India: Research Signpost, 2007.

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L, Laskin Debra, ed. Cellular and molecular biology of nitric oxide. New York: Marcel Dekker, 1999.

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Antoniou, Hariclia. Functional promoter analysis of the endothelial constitutive nitric oxide synthase gene. Ottawa: National Library of Canada, 1995.

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Phul, Ravinder Kaur. Nitric oxide synthase in the spinal cord in motor neurodegenerative diseases. Birmingham: University of Birmingham, 1998.

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Steinbusch, Hendrik Wilhelm Maria, 1950-, Vente J. de, and Vincent Steven Robert 1954-, eds. Functional neuroanatomy of the nitric oxide system. Amsterdam: Elsevier, 2000.

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Book chapters on the topic "Nitric oxide synthase"

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Schomburg, Dietmar, and Dörte Stephan. "Nitric-oxide synthase." In Enzyme Handbook, 567–74. Berlin, Heidelberg: Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-57942-4_121.

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Clausen, Torben, José Luis Trejo, Mark P. Mattson, Alexis M. Stranahan, Joanna Erion, Rosa Maria Bruno, Stefano Taddei, and Melinda M. Manore. "Nitric Oxide Synthase." In Encyclopedia of Exercise Medicine in Health and Disease, 648. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-540-29807-6_9501.

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von der Leyen, H. E., and V. J. Dzau. "Therapeutic Potential of Nitric Oxide Synthase Gene Manipulation." In Nitric Oxide, 639–53. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-57077-3_25.

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Förstermann, U. "Regulation of Nitric Oxide Synthase Expression and Activity." In Nitric Oxide, 71–91. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-57077-3_4.

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Werner, E. R., and H. H. H. W. Schmidt. "Nitric-Oxide-Synthase Inhibitors II — Pterin Antagonists/Anti-Pterins." In Nitric Oxide, 137–58. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-57077-3_7.

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Parkinson, J. F. "Nitric Oxide Synthase Inhibitors I: Substrate Analogs and Heme Ligands." In Nitric Oxide, 111–35. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-57077-3_6.

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Aldred, Sarah. "Nitric Oxide Synthase (NOS)." In Encyclopedia of Behavioral Medicine, 1506–7. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-39903-0_1229.

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Tiro, Jasmin, Simon J. Craddock Lee, Steven E. Lipshultz, Tracie L. Miller, James D. Wilkinson, Miriam A. Mestre, Barbara Resnick, et al. "Nitric Oxide Synthase (NOS)." In Encyclopedia of Behavioral Medicine, 1338–40. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1005-9_1229.

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Aldred, Sarah. "Nitric Oxide Synthase (NOS)." In Encyclopedia of Behavioral Medicine, 1–2. New York, NY: Springer New York, 2019. http://dx.doi.org/10.1007/978-1-4614-6439-6_1229-2.

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Nakagawa, Takahiko, and Richard J. Johnson. "Endothelial Nitric Oxide Synthase." In Contributions to Nephrology, 93–101. Basel: KARGER, 2011. http://dx.doi.org/10.1159/000324954.

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Conference papers on the topic "Nitric oxide synthase"

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Wannemacher, Jacob, Brian Patt, Saradhadevi Varadharaj, Angela Sow, Jay Zweier, and Rami Khayat. "Endothelial Nitric Oxide Synthase Inhibition In OSA." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a5500.

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Лучникова, Татьяна, Tatyana Luchnikova, Ольга Приходько, and Olga Prikhodko. "NITRIC OXIDE IN EXHALED AIR AND ENDOTHELIAL NITRIC OXIDE SYNTHASE GENES IN PATIENTS WITH BRONCHIAL ASTHMA DURING PREGNANCY." In The VIII Congress of Pulmonologists of Siberia and the Far East with international participation. Far Eastern Scientific Center of Physiology and Pathology of Respiration, 2019. http://dx.doi.org/10.12737/conferencearticle_5ce4ed23b84f73.34087229.

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Breton, Carrie, Hyang-Min Byun, Xinhui Wang, Muhammad T. Salam, Kimberly D. Siegmund, and Frank D. Gilliland. "Air Pollution Is Associated With DNA Methylation In Nitric Oxide Synthase." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a5674.

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Jackson, Claire L., Jacqueline King, Edith N. Quinn, Peter M. Lackie, and Jane S. Lucas. "The Importance Of Being NNOS? Unique Localization Of Neuronal Nitric Oxide Synthase To Cilia And Investigating A Nitric Oxide Synthase-1 Polymorphism In Primary Ciliary Dyskinesia." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a5504.

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Salam, Muhammad T., Hyang-Min Byun, Carrie V. Breton, Xinhui Wang, Kimberly D. Siegmund, and Frank D. Gilliland. "Genetic And Epigenetic Variations In Inducible Nitric Oxide Synthase Promoter Region, Particulate Pollution And Exhaled Nitric Oxide In Children." In American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a5680.

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Bratt, Jennifer, Jerold Last, and Nicholas J. Kenyon. "Nitric Oxide And Nitric Oxide Synthase Enzymes In The Airways Of Mice Exposed To Ovalbumin: The Importance Of NOS2." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a4946.

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Palmer, LA, K. Brown-Steinke, K. deRonde, L. Que, and B. Gaston. "S-Nitrosylation/Denitrosylation Coupling and the Regulation of Endothelial Nitric Oxide Synthase." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a1963.

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Gopallawa, I., and R. J. Lee. "Akt-Dependent Regulation of Nitric Oxide Synthase and Inflammation in Cystic Fibrosis." In American Thoracic Society 2021 International Conference, May 14-19, 2021 - San Diego, CA. American Thoracic Society, 2021. http://dx.doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1239.

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Dooper, Marten. "Nitric oxide synthase genetic variant is a risk factor for suicidal behaviour." In 35th ECNP Congress, edited by Christina Dalla. Baarn, the Netherlands: Medicom Medical Publishers, 2022. http://dx.doi.org/10.55788/c63a9364.

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Klinnikova, A. A., G. A. Danilova, and N. P. Aleksandrova. "The role of neuronal NO synthase in the respiratory effects of TNF-α." In VIII Vserossijskaja konferencija s mezhdunarodnym uchastiem «Mediko-fiziologicheskie problemy jekologii cheloveka». Publishing center of Ulyanovsk State University, 2021. http://dx.doi.org/10.34014/mpphe.2021-115-118.

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It was shown that an increase level of proinflammatory cytokines has a modulating effect on the reflex control of respiration. The aim of this study was to investigate the involvement of neuronal nitric oxide synthase (nNOS) in the mechanisms of the influence of an increased level of Tumor necrosis factor – α (TNF-α) on the hypoxic ventilatory response. To achieve this goal, experiments were carried out on urethane anesthetized rats with intravenous administration of TNF-α before and after pretreatment with 7-nitroindazole specific nNOS inhibitor. The hypoxic ventilation response was assessed by rebreathing with a hypoxic gas mixture before and after administration of TNF-α. We found that TNF-α decreased the ventilatory response to hypoxia. Pretreatment with nNOS inhibitor reduced respiratory effects of TNF-α. Key words: cytokines, TNF-α, hypoxia, chemoreflex, respiration, ventilation, neuronal nitric oxide synthase.
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