Journal articles: 'NFF'

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Govindan, Vaniespree, Salmah Husseinsyah, Teh Pei Leng, Marliza Mosthapa Zakaria, and Faisal Amri Tanjung. "Regenerated Cellulose/Nypa Fruticans Fiber Biocomposite Films Using Ionic Liquid." Applied Mechanics and Materials 754-755 (April 2015): 266–70. http://dx.doi.org/10.4028/www.scientific.net/amm.754-755.266.

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Regenerated cellulose (RC) biocomposite films from Nypa Fruticans Fiber (NFF) and microcrystalline cellulose (MCC) were prepared by dissolving cellulose in lithium chloride (LiCl) and dimethylacetamide (DMAc). The effect of NFF content on tensile properties and X-ray diffraction were studied. The results found that the tensile strength and Young’s modulus of RC biocomposite films increased from 1 wt% to 3 wt% of NFF content and decreased at 4 wt% of NFF content. The elongation at break of RC biocomposite films decreased with increases NFF content. The crystallinity of RC biocomposite films also showed the highest crystallinity at 3 wt% of NFF content.

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Khan, Samir. "Research study from industry-university collaboration on “No Fault Found” events." Journal of Quality in Maintenance Engineering 21, no. 2 (May 11, 2015): 186–206. http://dx.doi.org/10.1108/jqme-01-2014-0004.

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Purpose – The purpose of this paper is to present the successes and barriers from an industry-university partnership on studying the impact of No Fault Found (NFF) events. As a consequence, various opportunities are explored to engage with industry to investigate the problem. A comprehensive training is also outlined to ensure that experience and troubleshooting techniques can be disseminated as guidelines across businesses. Design/methodology/approach – The study was performed by Cranfield University in collaboration with industrial partners on identifying the impact of the NFF problem within engineering services. This includes discussions with maintenance engineers, outcomes from a symposium organised specifically on NFF and the authors’ own experiences with the issue. Findings – The paper discusses the continuing serious problem with NFF events found at various maintenance echelons, and suggests a need for formal postgraduate training to be taught within the field of maintenance management. This includes not just technical issues, but also encompassing organisational structures, cultures and behaviours. Since focusing only on one issue at a time does not suffice in dealing with the NFF problem, an integrated approach is required for modern maintenance services and operations. Research limitations/implications – Higher education learning outcomes have been outlined for competent engineering personnel, to broaden their understanding on the subject area. This is based on discussions with industrial collaborators and recently published material. Practical implications – This paper emphasises the importance of the breath of interaction channels and demonstrates the opportunities for effective knowledge exchange by using the activities at Cranfield University to demonstrate their usefulness. The arguments clearly lead to the necessity of academia in this type of industrial problem. However, the presence of a university in this case is not as the sole problem solver, but the rather to act as a collaborative medium between various other outlets. Further ideas proposed, such as constructing guidelines for industries in handling NFF problems and benchmarking tools, can serve as real products that can be benefit industries. The study also aims to promote best practice in the field of maintenance management and outlines the foundations for NFF training material. Originality/value – The originality of the paper is that it presents a structured methodology for engaging with industry. It also outlines a curriculum for NFF training. It essentially serves as a road-map for research and offers a detailed account of areas that need to be taken into account in order to reduce the likely event of NFF.

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Wakiya, Takeru, Manabu Tanaka, and Hiroyoshi Kawakami. "Fabrication and Electrolyte Characterizations of Nanofiber Framework-Based Polymer Composite Membranes with Continuous Proton Conductive Pathways." Membranes 11, no. 2 (January 27, 2021): 90. http://dx.doi.org/10.3390/membranes11020090.

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For future fuel cell operations under high temperature and low- or non-humidified conditions, high-performance polymer electrolyte membranes possessing high proton conductivity at low relative humidity as well as suitable gas barrier property and sufficient membrane stability are strongly desired. In this study, novel nanofiber framework (NfF)-based composite membranes composed of phytic acid (Phy)-doped polybenzimidazole nanofibers (PBINf) and Nafion matrix electrolyte were fabricated through the compression process of the nanofibers. The NfF composite membrane prepared from the pressed Phy-PBINf showed higher proton conductivity and lower activation energy than the conventional NfF composite and recast-Nafion membranes, especially at low relative humidity. It is considered that the compression process increased the nanofiber contents in the composite membrane, resulting in the construction of the continuously formed effective proton conductive pathway consisting of the densely accumulated phosphoric acid and sulfonic acid groups at the interface of the nanofibers and the Nafion matrix. Since the NfF also improved the mechanical strength and gas barrier property through the compression process, the NfF composite polymer electrolyte membranes have the potential to be applied to future fuel cells operated under low- or non-humidified conditions.

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Albert, James S., Victor A. Tagliacollo, and Fernando Dagosta. "Diversification of Neotropical Freshwater Fishes." Annual Review of Ecology, Evolution, and Systematics 51, no. 1 (November 2, 2020): 27–53. http://dx.doi.org/10.1146/annurev-ecolsys-011620-031032.

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Neotropical freshwater fishes (NFFs) constitute the most diverse continental vertebrate fauna on Earth, with more than 6,200 named species compressed into an aquatic footprint <0.5% of the total regional land-surface area and representing the greatest phenotypic disparity and functional diversity of any continental ichthyofauna. Data from the fossil record and time-calibrated molecular phylogenies indicate that most higher taxa (e.g., genera, families) diversified relatively continuously through the Cenozoic, across broad geographic ranges of the South American platform. Biodiversity data for most NFF clades support a model of continental radiation rather than adaptive radiation, in which speciation occurs mainly in allopatry, and speciation and adaptation are largely decoupled. These radiations occurred under the perennial influence of river capture and sea-level oscillations, which episodically fragmented and merged portions of adjacent river networks. The future of the NFF fauna into the Anthropocene is uncertain, facing numerous threats at local, regional, and continental scales.

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Eggen, Spencer, and Farzan Sasangohar. "Contribution of Technical and Human Factors to “No Fault Found” Events." Proceedings of the Human Factors and Ergonomics Society Annual Meeting 61, no. 1 (September 2017): 1679. http://dx.doi.org/10.1177/1541931213601908.

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Multicomponent products that combine hardware and software (cars, airplanes, and telephones, to name a few) are everywhere in our lives. The commercial release of such products is a compromise between performance capabilities, competitive pricing, and time to market (Challa, Rundle, & Pecht, 2013). As product performance increases, system complexity and the number of failure modes also increase. Of particular importance are “No Fault Found” (NFF) events that occur when a user records a system error and subsequent investigations fail to uncover the reason for the system malfunction – the root cause is unknown (Jones & Hayes, 2001). NFF can result in high warranty costs, product recalls, and diminished reputation (Challa et al., 2013). Surprisingly, most organizations do not explicitly calculate the costs of NFF or use a framework to estimate them (Erkoyuncu, Khan, Hussain, & Roy, 2016). A defining aspect of NFF is the discrepancy between actual and anticipated use conditions (Challa et al., 2013). Anticipated use is often defined by qualification, the passing of tests that demonstrate when a product meets nominal design and manufacturing specifications (Challa et al., 2013). A popular form of qualification is standards-based testing due to its speed, low cost, and applicability to many products (Challa et al., 2013). Standards such as Military Standard (MIL-STD) meet these criteria, but are often inappropriate for specific, actual-use conditions in the field. For example, the Ford Motor Company designed thick film integrated (TFI) ignition modules based on a set of laboratory standards. Cars used in hot climates experienced numerous failures that were initially classified as NFF (because these failures could not be reproduced under the milder laboratory conditions) (Thomas et al., 2002). One remedy to this problem would be to adopt more stringent engineering specifications for qualification. In this research, we analyzed NFF across four industries – automotive electronics, aerospace, medical equipment, and consumer electronics. The analysis is based on four contributors to NFF: testing procedures, intermittent failures, environmental factors, and human factors. Intermittent failures are the re-appearance of equipment failure after remedial actions have taken place (Thomas et al., 2002). Environmental factors (also referred to as environmental monitoring) are the context (or “background”) conditions in which the NFF event occurs. These factors can take on a variety of forms, from vibration and humidity in an aircraft to the diverse demographics of users of a consumer electronic product (Kim & Christiaans, 2016; Moffat, Abraham, Desmulliez, Koltsov, & Richardson, 2008). Case studies (representing each of the four industries) demonstrate that the existing strategies for reducing the occurrence of NFF events are limited. Addressing the four contributors to NFF (testing procedures, intermittent failures, environmental factors, and human factors) allows for the development of a systematic approach to reduce these events. First, one must distinguish between “hard” and “soft” failures. Hard failures are technical or equipment reliability failures (den Ouden, Yuan, Sonnemans, & Brombacher, 2006; Kushniruk & Patel, 2004). Soft failures occur when products fail to meet usability expectations, despite functioning from a technical, reliability standpoint (den Ouden et al., 2006). Hard failures are relevant to the aerospace and automotive electronics industry case studies, while soft failures pertain to medical equipment and consumer electronics. Analysis reveals a number of key insights, including the impact of proper failure classification (what is or is not a NFF event). Proper classification enables organizations to quantify how products perform in the field and which corrective actions are needed to improve reliability and usability.

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Starovoytov, Oleg N., Pengzhi Zhang, Piotr Cieplak, and Margaret S. Cheung. "Induced polarization restricts the conformational distribution of a light-harvesting molecular triad in the ground state." Physical Chemistry Chemical Physics 19, no. 34 (2017): 22969–80. http://dx.doi.org/10.1039/c7cp03177g.

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Free energy surface of the light-harvesting triad employing a non-polarizable force field (NFF) and a polarizable force field (PFF) shows that induced polarization limits the motion of rotation about chemical bonds as well as bending at the porphyrin, which are prominent using the NFF, thus limiting the conformational space of the triad.

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Santana, Ulisses Andrade, José Luiz Sandez de Carvalho, Arie Fitzgerald Blank, and Renata Silva-Mann. "Capacidade combinatória e parâmetros genéticos de genótipos de pinhão-manso quanto a caracteres morfoagronômicos." Pesquisa Agropecuária Brasileira 48, no. 11 (November 2013): 1449–56. http://dx.doi.org/10.1590/s0100-204x2013001100005.

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O objetivo deste trabalho foi determinar as capacidades geral e específica de combinação, os parâmetros genéticos e a correlação entre caracteres morfoagronômicos, em acessos de pinhão-manso (Jatropha curcas). Utilizou-se o delineamento experimental de blocos ao acaso, com três repetições. Foram avaliados os caracteres: PR, produção de sementes; AP, altura de planta; NRS, número de ramos secundários; NFF, número de flores femininas; DC, diâmetro de colo; P100, massa de 100 sementes; AR, altura de ramificação; e DCO, diâmetro de copa. A capacidade geral de combinação foi significativa para PR, NRS, DC, P100 e AR, enquanto a capacidade específica foi significativa apenas para NFF e NRS. As estimativas de herdabilidade foram superiores a 70%, em NRS, NFF, DC e AR. Observou-se correlações genotípicas positivas entre NRS e DC (0,942), NRS e AP (0,762), NRS e DCO (0,798), NRS e PR (0,759), DC e AP (0,738), DC e DCO (0,844), DC e PR (0,802), e DCO e PR (0,742); e negativas entre NRS e AR (-0,665), e DC e AR (-0,687). O NFF explicou mais de 50% da variação dos híbridos de pinhão-manso. A capacidade geral de combinação é preponderante na maioria das características avaliadas.

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Kurzawa, Timon. "1,1,2,2,3,3,4,4,4-Nonafluorobutane-1-sulfonyl fluoride (NfF)." Synlett 26, no. 10 (May 27, 2015): 1422–23. http://dx.doi.org/10.1055/s-0034-1380501.

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Ponnusamy, Duraisamy, Elena V. Kozlova, Jian Sha, Tatiana E. Erova, Sasha R. Azar, Eric C. Fitts, Michelle L. Kirtley, et al. "Cross-talk among flesh-eating Aeromonas hydrophila strains in mixed infection leading to necrotizing fasciitis." Proceedings of the National Academy of Sciences 113, no. 3 (January 5, 2016): 722–27. http://dx.doi.org/10.1073/pnas.1523817113.

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Necrotizing fasciitis (NF) caused by flesh-eating bacteria is associated with high case fatality. In an earlier study, we reported infection of an immunocompetent individual with multiple strains of Aeromonas hydrophila (NF1–NF4), the latter three constituted a clonal group whereas NF1 was phylogenetically distinct. To understand the complex interactions of these strains in NF pathophysiology, a mouse model was used, whereby either single or mixed A. hydrophila strains were injected intramuscularly. NF2, which harbors exotoxin A (exoA) gene, was highly virulent when injected alone, but its virulence was attenuated in the presence of NF1 (exoA-minus). NF1 alone, although not lethal to animals, became highly virulent when combined with NF2, its virulence augmented by cis-exoA expression when injected alone in mice. Based on metagenomics and microbiological analyses, it was found that, in mixed infection, NF1 selectively disseminated to mouse peripheral organs, whereas the other strains (NF2, NF3, and NF4) were confined to the injection site and eventually cleared. In vitro studies showed NF2 to be more effectively phagocytized and killed by macrophages than NF1. NF1 inhibited growth of NF2 on solid media, but ExoA of NF2 augmented virulence of NF1 and the presence of NF1 facilitated clearance of NF2 from animals either by enhanced priming of host immune system or direct killing via a contact-dependent mechanism.

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Fernández-Bravo, Ana, Paul B. Kilgore, Jourdan A. Andersson, Elizabeth Blears, Maria José Figueras, Nur A. Hasan, Rita R. Colwell, Jian Sha, and Ashok K. Chopra. "T6SS and ExoA of flesh-eating Aeromonas hydrophila in peritonitis and necrotizing fasciitis during mono- and polymicrobial infections." Proceedings of the National Academy of Sciences 116, no. 48 (November 11, 2019): 24084–92. http://dx.doi.org/10.1073/pnas.1914395116.

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An earlier report described a human case of necrotizing fasciitis (NF) caused by mixed infection with 4 Aeromonas hydrophila strains (NF1–NF4). While the NF2, NF3, and NF4 strains were clonal and possessed exotoxin A (ExoA), the NF1 strain was determined to be phylogenetically distinct, harboring a unique type 6 secretion system (T6SS) effector (TseC). During NF1 and NF2 mixed infection, only NF1 disseminated, while NF2 was rapidly killed by a contact-dependent mechanism and macrophage phagocytosis, as was demonstrated by using in vitro models. To confirm these findings, we developed 2 NF1 mutants (NF1ΔtseC and NF1ΔvasK); vasK encodes an essential T6SS structural component. NF1 VasK and TseC were proven to be involved in contact-dependent killing of NF2 in vitro, as well as in its elimination at the intramuscular injection site in vivo during mixed infection, with overall reduced mouse mortality. ExoA was shown to have an important role in NF by both NF1-exoA (with cis exoA) and NF2 during monomicrobial infection. However, the contribution of ExoA was more important for NF2 than NF1 in the murine peritonitis model. The NF2∆exoA mutant did not significantly alter animal mortality or NF1 dissemination during mixed infection in the NF model, suggesting that the ExoA activity was significant at the injection site. Immunization of mice to ExoA protected animals from NF2 monomicrobial challenge, but not from polymicrobial infection because of NF2 clearance. This study clarified the roles of T6SS and ExoA in pathogenesis caused by A. hydrophila NF strains in both mouse peritonitis and NF models in monomicrobial and polymicrobial infections.

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Fagundes, Lovane Klein, Nereu Augusto Streck, Sidnei José Lopes, Hamilton Telles da Rosa, Lidiane Walter, and Alencar Junior Zanon. "Desenvolvimento vegetativo em diferentes hastes da planta de mandioca em função da época de plantio." Ciência Rural 39, no. 3 (November 28, 2008): 657–63. http://dx.doi.org/10.1590/s0103-84782008005000097.

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Estudos sobre o desenvolvimento vegetativo da mandioca cultivada nas condições subtropicais do Brasil são escassos. O objetivo deste trabalho foi determinar o filocrono e o número final de folhas na haste principal e nas ramificações simpodiais de uma variedade de mandioca em diferentes épocas de plantio, em condições de clima subtropical. Um experimento de campo foi conduzido em Santa Maria, Rio Grande do Sul (RS), com quatro datas de plantio: 26/09/2006, 18/10/2006, 08/11/2006 e 28/11/2006. A variedade usada foi a FEPAGRO RS13, com caule do tipo simpodial tricotômico, no delineamento experimental inteiramente casualizado, com quatro tratamentos (datas de plantio) e quatro parcelas de 4,0 x 9,0m, com cinco fileiras e espaçamento 0,80 x 0,80m. Em seis plantas por parcela selecionadas aleatoriamente, foi feita a contagem semanal do número de folhas visíveis (NF) e do número final de folhas (NFF) da haste principal (HP) e das ramificações simpodiais de primeira (RS1) e de segunda (RS2) ordem. O filocrono (°C dia folha-1) foi estimado para HP, RS1 e RS2 pelo inverso do coeficiente angular da regressão linear entre NF e soma térmica acumulada, considerando a temperatura base de 14°C. O filocrono aumentou na seqüência HP<RS1<RS2, e o NFF teve variação inversa HP>RS1>RS2. Ambos filocrono e NFF variaram com a época de plantio, sendo o fotoperíodo uma possível causa da variação. Dentro das ramificações simpodiais RS1 e RS2, o filocrono e o NFF não são diferentes entre as hastes.

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Cronin, Anna. "NFF groups support AVA on vets crisis." Australian Veterinary Journal 79, no. 9 (September 2001): 584. http://dx.doi.org/10.1111/j.1751-0813.2001.tb10757.x.

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Prasasti, Sandy Aria. "STUDI KASUS MANAJEMEN SEKOLAH SEPAKBOLA (SSB) NGANJUK FOOTBALL FOUNDATION (NFF) KECAMATAN TANJUNGANOM KABUPATEN NGANJUK DI TENGAH PANDEMI COVID-19 TAHUN 2019/2020." Journal of SPORT (Sport, Physical Education, Organization, Recreation, and Training) 4, no. 2 (December 25, 2020): 107–13. http://dx.doi.org/10.37058/sport.v4i2.2468.

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Wabah virus COVID-19 telah mengganggu aktivitas sehari-hari di seluruh dunia dan diumumkan sebagai pandemi oleh Organisasi Kesehatan Dunia (WHO).Shopee Liga 1 2020 pun resmi dihentikan mulai Senin (16/3/2020). Di wilayah Kabupaten Nganjuk terdapat Sekolah Sepakbola (SSB) yaitu Nganjuk Football Foundation (NFF) yang berada di wilayah Kecamatan Tanjunganom Kabupaten Nganjuk. Dimana sekolah sepakbola (SSB) ini terbilang sebagai SSB yang relatif baru dengan manajemen dan sistem kepelatihan yang sistematis. Tujuan penelitian ini adalah untuk mengetahui bagaimana keadaan manajemen pada tingkatan sekelas sekolah sepakbola (SSB) dalam mengelola manajemennya di tengah pandemi COVID-19. Penelitian ini adalah studi kasus tunggal terpancang yaitu studi kasus yang menyajikan suatu kasus yang unik atau ekstern dan mencangkup lebih dari satu unit analisis. Teknik pengumpulan data dengan cara melakukan observasi lapangan dan wawancara dengan para narasumber antara lain: pengurus, pelatih, orangtua siswa, dan atlet. Hasil penelitian menunjukkan bahwa keadaan manajemen sekolah sepakbola (SSB) Nganjuk Football Foundation (NFF) pada masa pandemi ini tetap berjalan dengan berbagai bentuk penyesuaian sesuai protokol dari pemerintah dan KONI. Simpulan penelitian ini adalah sekolah sepakbola (SSB) Nganjuk Football Foundation (NFF) memiliki unsur-unsur yang memadai dengan pengelolaan manajemen yang baik dapat menyesuaikan di tengah pandemi COVID-19.

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Liya, Xi, and Pen Yan. "Design and Application of A Development Framework Based-on Shared Farm Digital Control Platform." E3S Web of Conferences 189 (2020): 01003. http://dx.doi.org/10.1051/e3sconf/202018901003.

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Agriculture through science and technology is an effective way to promote the development of agricultural economy. In response to the problem of the shortage of urban arable land and the barrenness of rural land, it is combined with the sharing economy and agriculture through the Internet platform to propose the concept of using idle rural land to realize urban people’s online pastoral life. Based on this, the application research on the integration of agriculture and the Internet has been carried out. Taking the needs of shared farm management as an example, through the analysis and research of Nginx, Flask and FFmpeg technologies, the development framework of NFF (Nginx+Flask+FFmpeg) web server with live broadcast function is designed. Based on the NFF framework, the management about land use patterns and planting methods in shared farms have been realized. Real-time live broadcast of farms has also been realized, which establishes a connection between consumers, growers and managers, and draws closer The distance between consumers and farms. The article focuses on the design ideas and application methods of the NFF framework in the agricultural management system, and the application of Blueprint technology in the live broadcast module. From the perspective of the application of the shared farm management system, the NFF framework can ensure the stability and scalability of the system functions, while also reducing the difficulty of development and improving the efficiency of development. It provides design ideas and application methods for Internet technology in agriculture. It is helpful to promote the sustainable development of the concept of “Internet + Sharing”, provides a stage for the sharing economy to drive agricultural development, and provides a reference for the structure of a new agricultural management system.

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Lin, Yu, Zhi Yang, Duanlin Cao, and Yaqiong Gong. "Electro-deposition of nickel–iron nanoparticles on flower-like MnCo2O4 nanowires as an efficient bifunctional electrocatalyst for overall water splitting." CrystEngComm 22, no. 8 (2020): 1425–35. http://dx.doi.org/10.1039/c9ce01921a.

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Hans, Carl, and Karl Hribernik. "NFF Special Session – Potentials of Applying Methods, Tools, Processes and Knowledge from Testing in Product Development to the NFF Problem." Procedia CIRP 22 (2014): 53–58. http://dx.doi.org/10.1016/j.procir.2014.07.131.

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Wiener-Fererhofer, Alexander. "Credit rating process." Journal of Family Business Management 7, no. 3 (October 9, 2017): 256–90. http://dx.doi.org/10.1108/jfbm-06-2017-0013.

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Purpose The purpose of this paper is to analyze which key financial factors are appropriate for measuring a credit rating score for family firms. In the recent literature, there exists a vast number of studies which evaluates performance differences between family and non-family firms (NFF). However an analysis with regards to a distinction between credit rating scores of family-orientated businesses compared to their counterparts in Austria has not been examined so far. Design/methodology/approach In order to bridge this research gap, an empirical model based on Moody’s credit rating methodology is used to address these issues. Therefore, the relevant data were taken from the 600 largest, both listed and non-listed, companies of Austria. The statistical measurements refer to a comparison of the means resulting from quantitative rating categories (profitability, leverage structure, liquidity development and firm size). Findings The results of this empirical research show that family firms achieve better values in profitability, leverage structure and liquidity development based on credit rating scores. Only firm size represents no significant differences between family and NFF. Originality/value This study will contribute to the existing literature in the academic area of family business research and offers a framework for future empirical analysis in this field. Furthermore, this paper provides important information that will help both family and NFF accomplish their financial strategies related to credit rating transitions.

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F. Simões Vieira, Elisabete. "The effect on the performance of listed family and non-family firms." Managerial Finance 40, no. 3 (March 4, 2014): 234–53. http://dx.doi.org/10.1108/mf-06-2013-0134.

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Purpose – The purpose of this paper is to examine whether the ownership of public firms is related to accounting and market performance, comparing family and non-family listed firms. Design/methodology/approach – The paper uses regression analysis, considering a sample of Portuguese family and non-family firms (NFF) for the period between 1999 and 2010. Findings – Overall, the results show that family firms (FF) are older, are more indebted and have higher debt costs than NFF. However, they present lower levels of risk. The evidence suggests that FF outperform NFF when the author considers a market performance measure. The market performance of family-controlled firms is more sensitive to the crisis periods and age, compared to their counterparts. The empirical findings suggest that under economic adversity, the performance is especially compromised by the firms' age. Research limitations/implications – A limitation of this study is the small size of the sample, which derives from the small size of the Portuguese stock market, the Euronext Lisbon. Originality/value – This paper offers some insights on the ownership of public firms and firm performance by investigating a small European economy. The study also contributes to the stream of firm performance, considering new independent variables as determinants of firm performance, such as operational risk. Finally, the study examines the interaction between ownership and performance under both steady and adverse economic conditions, giving the opportunity to analyze whether firm performance differs according to market conditions.

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Santillán, Moisés. "Periodic Forcing of a 555-IC Based Electronic Oscillator in the Strong Coupling Limit." International Journal of Bifurcation and Chaos 26, no. 03 (March 2016): 1630007. http://dx.doi.org/10.1142/s021812741630007x.

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We designed and developed a master-slave electronic oscillatory system (based on the 555-timer IC working in the astable mode), and investigated its dynamic behavior regarding synchronization. For that purpose, we measured the rotation numbers corresponding to the phase-locking rhythms achieved in a large set of values of the normalized forcing frequency (NFF) and of the coupling strength between the master and the slave oscillators. In particular, we were interested in the system behavior in the strong-coupling limit, because such problem has not been extensively studied from an experimental perspective. Our results indicate that, in such a limit, a degenerate codimension-2 bifurcation point at NFF = 2 exists, in which all the phase-locking regions converge. These findings were corroborated by means of a mathematical model developed to that end, as well as by ad hoc further experiments.

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Franke, Marco, Konstantin Klein, and Klaus-Dieter Thoben. "Interoperable Information Exchange as Enabler of NFF Related TES." Procedia CIRP 59 (2017): 240–45. http://dx.doi.org/10.1016/j.procir.2016.08.037.

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Tang, Yu, D. Prabhakar Reddy, and Biao Yu. "A dehydrative glycosylation protocol mediated by nonafluorobutanesulfonyl fluoride (NfF)." Tetrahedron 78 (January 2021): 131800. http://dx.doi.org/10.1016/j.tet.2020.131800.

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Aguirre, Paula B., Yahya K. Al-Hinai, Teryl R. Roper, and Armand R. Krueger. "Apple Tree Rootstock and Fertilizer Application Timing Affect Nitrogen Uptake." HortScience 36, no. 7 (December 2001): 1202–5. http://dx.doi.org/10.21273/hortsci.36.7.1202.

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Nitrogen (N) uptake was compared on 10 dwarf apple rootstocks (M.9 EMLA, M.26 EMLA, M.27 EMLA, M.9 RN29, Pajam 1, Pajam 2, B.9, Mark, B.469, and M.9 T337) grafted with the same scion (`Gala') in a four year-old orchard. Trees were treated in either Spring or Fall 1998 with 40 g of soil applied actual N per tree using ammonium nitrate enriched to 1% 15N. Both percentage of N (%N) and N from fertilizer (NFF) in leaf tissue were highly affected by the rootstock and the season of N application. Generally, higher %N and NFF were observed for spring than fall applications, except for leaves collected during early June 1998. Generally, M.26 EMLA, M.27 EMLA, and M.9 RN29 were the most efficient rootstocks in N uptake for spring applied nitrogen. M.9 EMLA was most efficient late in the season following fall application. Mark was more efficient early in the season for fall applied N than spring application. However, trees on Mark rootstock had the lowest %N throughout the season regardless of the time of N application. Pajam 1 and Pajam 2 were the least efficient rootstocks in N uptake following fall N application. Rootstock also significantly affected %N and NFF of wood tissue. Generally, trees on B.469 had the highest %N in their wood regardless of the season of application. No single rootstock had consistently higher N from fertilizer in their wood tissue after spring application. At the May 1999 sampling date, M.26 EMLA had higher NFF than M.27 EMLA, Pajam 1, Pajam 2, and B.9 with a fall application. Other rootstocks were intermediate. Samples collected in August showed that Pajam 1 was the least efficient rootstock in N uptake for fall applied N compared to other rootstocks, except for Pajam 2 and B.9 that were intermediate. Leaf and wood tissue analysis showed that different rootstocks had different N uptake efficiencies throughout the season. Generally, M.26 EMLA, M.27 EMLA, M.9 RN29 and M.9 EMLA were more efficient at N uptake regardless the season of N application. Pajam 1 and Pajam 2 were the least efficient.

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Farooq, Muhammad, Qamruz zaman, Muhammad Ijaz, Said Farooq Shah, and Mutua Kilai. "A Novel Approach to Increase the Goodness of Fits with an Application to Real and Simulated Data Sets." Mathematical Problems in Engineering 2021 (July 30, 2021): 1–11. http://dx.doi.org/10.1155/2021/9717872.

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In practice, the data sets with extreme values are possible in many fields such as engineering, lifetime analysis, business, and economics. A lot of probability distributions are derived and presented to increase the model flexibility in the presence of such values. The current study also focuses on investigations to derive a new probability model New Flexible Family (NFF) of distributions. The significance of NFF is carried out using the Weibull distribution called New Flexible Weibull distribution or in short NFW. Various mathematical properties of NFW have been discussed including the estimation of parameters and entropy measures. Two real data sets with extreme values and a simulation study have been conducted so as to delineate the importance of NFW. Furthermore, NFW is compared with other existing probability distributions; numerically, it has been observed that the new mechanism of producing the lifetime probability distributions plays a significant role in making predictions about the population than others using the data sets with extreme values.

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Kang, D., C. Choe, E. S. Kim, H. Y. Yang, C. G. Hur, E. J. Kim, and J. Han. "237 POTASSIUM CONCENTRATION AND mRNA LEVELS OF POTASSIUM CHANNELS DECREASED IN CYSTIC OVARIAN FOLLICLE FLUID." Reproduction, Fertility and Development 19, no. 1 (2007): 234. http://dx.doi.org/10.1071/rdv19n1ab237.

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Cystic ovarian follicle (COF) is one of the most frequently diagnosed ovarian diseases and a major cause of reproductive failure in cattle. Despite an abundance of reports on this subject, the exact pathogenesis of COF still remains unclear. It is generally accepted that disruption of the hypothalmo-pituitary-gonadal axis, by endogenous and/or exogenous factors, causes cystic formation. We here examined whether ion concentration and expression of ion channels are altered in the follicle fluid derived from a Korean native cow with COF. In an ovary with a cystic follicle, granulosa cell layers were exfoliated; the theca interna was thinner than that in an ovary without cystic follicle, based on histological examination. Concentrations of K+, Na+, and Cl- in COF fluid (COFF) were 10.4 � 3.5 mM, 138 � 12 mM, and 104.9 � 7.0 mM, respectively. In COFF, K+ concentration showed a significant difference from the value observed in normal follicle fluid (NFF) (P < 0.05; NFF: 10.4 � 3.5 mM vs. COFF: 6.2 � 0.8 mM). The total numbers of follicles observed (normal, 3–5 mm in diameter vs. COF, 20–30 mm in diameter) were 200 and 20 in normal and COF, respectively. To compare mRNA expression of K+ channels, we performed semiquantitative RT-PCR using follicle fluid and ovaries with or without cystic follicles. RT-PCR showed that mRNA levels of TASK channels (TASK-1, TASK-3, and TASK-5) decreased by 50% in COFF and an ovary with cystic follicles compared to NFF and a normal ovary. TASK channels are involved in apoptosis of mammalian cells. Our results suggest that potassium may play an important role in the pathogenesis of COF.

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Curran, Clive-Steven, and Jens Leker. "Patent indicators for monitoring convergence – examples from NFF and ICT." Technological Forecasting and Social Change 78, no. 2 (February 2011): 256–73. http://dx.doi.org/10.1016/j.techfore.2010.06.021.

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Söderholm, Peter. "A system view of the No Fault Found (NFF) phenomenon." Reliability Engineering & System Safety 92, no. 1 (January 2007): 1–14. http://dx.doi.org/10.1016/j.ress.2005.11.004.

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Leichsenring, Mirtes Loeschner, Sônia Cavinatto, and Eliane Molina Psaltikidis. "Avaliação de danos em nasofibroscópio flexível desinfetado com ácido peracético." Revista SOBECC 22, no. 3 (September 15, 2017): 137. http://dx.doi.org/10.5327/z1414-4425201700030003.

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Objetivo: Avaliar a ocorrência de possíveis danos em nasofibroscópios causados pela desinfecção em ácido peracético. Método: Pesquisa aplicada.Três nasofibroscópios novos, submetidos à desinfecção com ácido peracético, foram acompanhados e fotografados em microscópio esteroscópio, ao longode 18 meses, para avaliar o comportamento do polímero e da fibra do nasofibroscópio, relacionado ao uso desse desinfetante. Houve capacitação das equipesde enfermagem e médica com ênfase no manuseio correto e no processamento seguro das fibras. Resultados: As fibras foram analisadas e fotografadas regularmente,durante o período do estudo, totalizando 3.979 usos. Foi observado, em todas as fibras, craquelamento do excedente de material adesivo em tornoda área de vedação das fibras, sem comprometimento funcional. Um nasofibroscópio flexível (NFF), após mais de 2.000 usos, apresentou fissuras superficiaisna cobertura da ponta distal da fibra, sem, contudo, comprometer o teste de vedação. Conclusão: O ácido peracético, na formulação utilizada e no períodoestudado, não causou danos funcionais ou oxidação nos NFFs, apesar de o fabricante recomendar a desinfecção por solução de aldeídos.

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Kerkhoff, Hans G., and Hassan Ebrahimi. "Investigation of Intermittent Resistive Faults in Digital CMOS Circuits." Journal of Circuits, Systems and Computers 25, no. 03 (December 28, 2015): 1640023. http://dx.doi.org/10.1142/s0218126616400235.

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No fault found (NFF) is a major threat in extremely dependable high-end process node integrated systems, in e.g., avionics. One category of NFFs is the intermittent resistive fault (IRF), often originating from bad (e.g., via- or TSV-based) interconnections. This paper will show the impact of these faults on the behavior of a digital CMOS circuit via simulation. As the occurrence rate of this kind of defects can take e.g., one month, while the duration of the defect can be as short as 50[Formula: see text]ns, thus to evoke and detect these faults is a huge scientific challenge. Two methods to detect short pulses induced by IRFs are proposed. To improve the task of maintenance of avionics and reduce the current high debugging costs, an on-chip data logging system with time stamp and stored environmental conditions is introduced. Finally, a hardware implementation of an IRF generator is presented.

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Frank, Tara, Tracy Caldwell, Fabien Ca, Tamara Alam, and Melissa Fuster. "A Quantitative Assessment of Changes in the Consumer Nutrition Environments of New York City Hispanic Caribbean Restaurants During the COVID-19 Pandemic." Current Developments in Nutrition 5, Supplement_2 (June 2021): 220. http://dx.doi.org/10.1093/cdn/nzab029_021.

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Abstract Objectives (1) Examine changes in healthy food availability among Hispanic Caribbean restaurants (HCR) in response to COVID-19. (2) Assess the association between changes and restaurant type. Methods A random sample of HCRs (n = 89) offering Cuban, Dominican, Puerto Rican cuisine, were examined in Summer 2019 (T1) using the NEMS-HCR, an adapted version of the Nutrition Environment Measures Survey for Restaurants (NEMS-R) and reassessed after the onset of COVID-19 in January 2021 (T2, n = 76) using online menus. We examined menu changes between T1 and T2 data sets in the NEMS-HCR overall healthy food availability (HFA) score, and specific variables: the number of healthy main dish salads (HMDS) and the menu proportion of nonfried foods (NFF) on the menu. We then examined changes by restaurant type (sit-down vs. counter-style) using repeated measures ANOVA. Results Between T1 and T2, 7 HRCs permanently closed, 1 closed for the season, and 5 were excluded due to lack of online menus. Mean proportion of NFF significantly decreased from 71.7% ± 17.5 (T1) to 66.1% ± 17.8 (T2) (P = 0.002). Changes in HFA scores (4.5 ± 2.0 to 4.1 ± 2.2) and HMDS (1.7 ± 2.8 to 1.8 ± 3.0) were not statistically significant (P = 0.06 and P = 0.65, respectively). Repeated measures ANOVA indicated no correlation between the decrease in availability of NFF between T1 and T2 and restaurant type (P = 0.29). Conclusions Restaurants can play a significant role in the mitigation of diet-related diseases such as cardiovascular disease and diabetes by providing customers with healthy menu offerings. Our study showed a decrease in healthier menu options, particularly non-fried entrees, contributing to our understanding of how restaurants may need to adapt for their own survival in times of crisis such as a pandemic or disaster. Because unfavorable menu options can contribute to the rising incidence of diet-related chronic diseases within the community, more research is needed to understand how restaurants respond to crises in order to better support the preservation of HFA within their menu selections, and the effects of these changes in customers’ diets. Funding Sources CUNY PSC Award and NIH National Heart, Lung, and Blood Institute

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Grim, Christopher J., Elena V. Kozlova, Duraisamy Ponnusamy, Eric C. Fitts, Jian Sha, Michelle L. Kirtley, Christina J. van Lier, et al. "Functional Genomic Characterization of Virulence Factors from Necrotizing Fasciitis-Causing Strains of Aeromonas hydrophila." Applied and Environmental Microbiology 80, no. 14 (May 2, 2014): 4162–83. http://dx.doi.org/10.1128/aem.00486-14.

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ABSTRACTThe genomes of 10Aeromonasisolates identified and designatedAeromonas hydrophilaWI, Riv3, and NF1 to NF4;A. dhakensisSSU;A. jandaeiRiv2; andA. caviaeNM22 and NM33 were sequenced and annotated. Isolates NF1 to NF4 were from a patient with necrotizing fasciitis (NF). Two environmental isolates (Riv2 and -3) were from the river water from which the NF patient acquired the infection. While isolates NF2 to NF4 were clonal, NF1 was genetically distinct. Outside the conserved core genomes of these 10 isolates, several unique genomic features were identified. The most virulent strains possessed one of the following four virulence factors or a combination of them: cytotoxic enterotoxin, exotoxin A, and type 3 and 6 secretion system effectors AexU and Hcp. In a septicemic-mouse model, SSU, NF1, and Riv2 were the most virulent, while NF2 was moderately virulent. These data correlated with high motility and biofilm formation by the former three isolates. Conversely, in a mouse model of intramuscular infection, NF2 was much more virulent than NF1. Isolates NF2, SSU, and Riv2 disseminated in high numbers from the muscular tissue to the visceral organs of mice, while NF1 reached the liver and spleen in relatively lower numbers on the basis of colony counting and tracking of bioluminescent strains in real time byin vivoimaging. Histopathologically, degeneration of myofibers with significant infiltration of polymorphonuclear cells due to the highly virulent strains was noted. Functional genomic analysis provided data that allowed us to correlate the highly infectious nature ofAeromonaspathotypes belonging to several different species with virulence signatures and their potential ability to cause NF.

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Streck, Nereu Augusto, Diego Garrido Pinheiro, Alencar Junior Zanon, Luana Fernandes Gabriel, Thiago Schmitz Marques Rocha, André Trevisan de Souza, and Michel Rocha da Silva. "Efeito do espaçamento de plantio no crescimento, desenvolvimento e produtividade da mandioca em ambiente subtropical." Bragantia 73, no. 4 (December 2014): 407–15. http://dx.doi.org/10.1590/1678-4499.0159.

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O objetivo neste trabalho foi analisar o efeito de diferentes espaçamentos de plantio no crescimento, desenvolvimento e produtividade de hastes e raízes comerciais de mandioca cultivada em ambiente subtropical no Rio Grande do Sul, Brasil. Os tratamentos foram em quatro espaçamentos: 0,8x0,8 m; 1,0x1,0 m; 1,2x1,2 m e 1,5x1,5 m, que correspondem às densidades 15.625 plantas ha-1, 10.000 plantas ha-1, 6.944,45 plantas ha-1 e 4.444,45 plantas ha-1, respectivamente. A cultivar usada foi a Fepagro - RS 13. As variáveis de crescimento e desenvolvimento analisadas foram área foliar verde, altura das plantas, número de folhas senescidas, comprimento de entrenó, número final de folhas (NFF), número de brotações laterais, tamanho final de folhas, filocrono e produtividade de haste e raiz em massa fresca e seca. O índice de área foliar máximo e o filocrono aumentam à medida que aumenta a densidade de plantio. O tamanho final de folha e o número de brotações laterais aumentaram à medida que diminuiu a densidade de plantio. O NFF diferiu apenas na segunda ramificação simpodial (RS2), com maior número de folhas nas plantas espaçadas a 1,5x1,5 m. A produtividade de hastes na cultivar Fepagro - RS 13 não varia com o espaçamento de plantio, mas a produtividade de raízes por área é maior nas densidades maiores, enquanto que a produtividade por planta e por raiz comercial é maior nas densidades menores.

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LIEW, K. W., and N. S. M. EL-TAYEB. "THE EFFECT OF ROTOR DISC MATERIAL ON TRIBO BEHAVIOR OF AUTOMOTIVE BRAKE PAD MATERIALS." Surface Review and Letters 15, no. 05 (October 2008): 625–33. http://dx.doi.org/10.1142/s0218625x08011925.

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This work aims to investigate the effect of two different counterdisc materials, i.e. gray cast iron (GCI) and ductile gray cast iron (DGCI) on tribo behavior of non-commercial frictional materials (NF1, NF2, NF4, and NF5) and two other chosen commercial brake pads (CMA and CMB) under dry sliding contact conditions. The four non-commercial frictional materials were fabricated with various percentages of phenolic binder resin (15 and 20 vol.%) and reinforced with steel fibers (15 and 20 vol.%) using hot press molding methods. Tribo tests were carried out using a small-scale tribo-tester of pad-on-disc type. Friction coefficient and wear of non-commercial and commercial brake pads were measured against each counterdisc (GCI and DGCI) and compared. Then, the friction and wear characteristic are discussed by comparing the experimental results obtained for each kind of cast iron. The results showed that maximum friction coefficient (0.4–0.5) of brake pad was attained at 2.22 MPa applied pressure and 2.1 m/s sliding speed when the frictional brake pad materials were tested against DGCI disc rotor. Meanwhile, similar wear rates for all frictional brake pad materials were sustained at higher applied pressure and sliding speed when tested against either type of rotor discs (GCI and DGCI). The results on the other hand, indicated that non-commercial materials NF1 and NF4, gave better wear resistance compared to other frictional pad materials. NF2 exhibited the lowest wear resistance when tested against GCI and DGCI rotor disc at all applied pressure and sliding speeds. The latter result is referred to the low percentage binder resin in the friction material NF2.

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Schons, Alfredo, Nereu Augusto Streck, Bruno Kraulich, Diego Garrido Pinheiro, and Alencar Junior Zanon. "Emissão de folhas e início de acumulação de amido em raízes de uma variedade de mandioca em função da época de plantio." Ciência Rural 37, no. 6 (December 2007): 1586–92. http://dx.doi.org/10.1590/s0103-84782007000600013.

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O número de folhas acumulado (NF) na haste principal está associado com o aparecimento de vários estádios de desenvolvimento da cultura da mandioca. O início de acumulação de amido (IAA) nas raízes tuberosas da mandioca marca o início da translocação dos fotoassimilados para o principal órgão de reserva nessa espécie. O objetivo deste trabalho foi estimar o filocrono e identificar um indicador morfológico baseado no NF para o IAA em mandioca plantada em diferentes épocas. Um experimento a campo foi conduzido em Santa Maria, RS, Brasil, com quatro épocas de plantio (28/09; 11/10; 16/11 e 27/12/2005). A variedade de mandioca usada foi a "RS 13", plantada em baldes de 12 litros, enterrados no espaçamento com 2,0 x 0,8m. O delineamento experimental foi o inteiramente casualizado com 11 repetições. A soma térmica diária (STd, °C dia) foi calculada a partir da emergência e acumulada por: STa = sigmaSTd. O IAA foi determinado nas plantas de cada balde quando uma raiz atingia um diâmetro de 1cm. O NF na data do IAA e o número final de folhas (NFF) até o primeiro simpódio também foram determinados. O filocrono variou de 20,3 a 29,5°C dia folha-1 e seus valores foram maiores quanto mais tardio foi o plantio. O NFF variou entre as épocas de plantio, aumentando com o atraso do plantio. O NF no IAA foi similar nas quatro épocas de plantio e ocorreu quando, em média, o NF corresponde a 20,9 (±1,0) folhas.

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Hockley, Chris, and Laura Lacey. "A Research Study of no Fault Found (NFF) in the Royal Air Force." Procedia CIRP 59 (2017): 263–67. http://dx.doi.org/10.1016/j.procir.2016.09.034.

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Judzentiene, Asta, Aida Stikliene, and Eugenija Kupcinskiene. "Changes in the Essential Oil Composition in the Needles of Scots Pine (Pinus sylvestrisL.) Under Anthropogenic Stress." Scientific World JOURNAL 7 (2007): 141–50. http://dx.doi.org/10.1100/tsw.2007.36.

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Unfavorable anthropogenic factors, such as air pollution, lead to biochemical responses in trees. Changes in the amounts of secondary metabolites may be early indicators of invisible injuries. The aim of this study was to evaluate composition of the essential oils in the needles of Scots pine (Pinus sylvestrisL.) growing in the areas affected by pollutant emissions of main factories in Lithuania: a nitrogen fertilizer factory (NFF), a cement factory (CF), and an oil refinery (OR). Totally, 14 pine stands were examined along transects from the factories (July 2005). Volatile components of the needles were extracted and analyzed by GC and GC/MS. Over 70 components of the essential oils were identified in current-year and 1-year-old needles.Along the CF transect for current-year needles, the percentage of diterpenes was decreasing with the increasing pH of the pine bark (r = -0.582;p< 0.05) or with the increasing concentration of SO2(r = -0.573;p< 0.05); for 1-year-old needles, the percentage of diterpenes was decreasing with the increasing pH of the bark (r = -0.534; p < 0.05). Along the OR transect, in both the current-year and 1-year-old needles, the percentage of diterpenes was decreasing with the increasing SO2(respectively, r = -0.773;p< 0.01; r = -0.486;p< 0.05); an opposite relation was true for sesquiterpenes (respectively, r = -0.751;p< 0.01; r = 0.785;p< 0.01). The view was different along the NFF transect. For current-year needles, the percentage of monoterpenes was decreasing with the increasing NH3(r = -0.669;p< 0.01); while the percentage of sesquiterpenes or oxysesquiterpenes was increasing with the increasing NH3(respectively, r = 0.540;p< 0.05 and r = 0.688;p< 0.01). For each transect, cluster analysis of the percentages of components of essential oils in the needles allowed us to distinguish the most contrasting stands according to the concentration of air pollutants. Current-year needles were more effective as indicators of the effects of pollution than 1-year-old needles in the case of the NFF and the OR transects, and both-aged needles were equally valuable in the case of the CF transect. The changes detected in the proportions of components of the essential oils in the needles of the trees affected by the industrial emissions may play a significant role in modifying the susceptibility of the pine stands to the biotic factors, and also may alter emissions of terpenes from the stands to the atmosphere.

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Streck, Nereu Augusto, Leosane Cristina Bosco, Simone Michelon, Hamilton Telles Rosa, Lidiane Cristine Walter, Gizelli Moiano de Paula, Cátia Camera, Isabel Lago, and Elio Marcolin. "Avaliação da resposta ao fotoperíodo em genótipos de arroz irrigado." Bragantia 65, no. 4 (2006): 533–41. http://dx.doi.org/10.1590/s0006-87052006000400001.

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A temperatura e o fotoperíodo são os fatores ambientais principais que influenciam a duração do ciclo de desenvolvimento das plantas de arroz (Oryza sativa L.). A resposta fotoperiódica da maioria dos genótipos modernos de arroz usados no sul do Brasil ainda não foi quantificada. O objetivo do trabalho foi identificar a resposta ao fotoperíodo de algumas cultivares de arroz irrigado cultivadas nessa região. Um experimento de campo foi instalado em Santa Maria (RS), durante os anos agrícolas de 2003/2004 e 2004/2005 com cinco épocas de semeadura por ano. Em 2003/2004, as épocas de semeadura foram 1.º/9/2003, 20/10/2003, 21/11/2003, 5/1/2004 e 29/1/2004 e em 2004/2005, as épocas de semeadura foram 2/9/2004, 7/10/2004, 4/11/2004, 3/12/2004 e 2/3/2005. As cultivares utilizadas foram IRGA 421, IRGA 416, IRGA 417, IRGA 420, BR-IRGA 409, BRS 7 "Taim" e EPAGRI 109, todas do tipo moderno, com diferentes ciclos de desenvolvimento, de muito precoce (IRGA 421) a tardio (EPAGRI 109). O delineamento experimental foi um trifatorial (cultivar, data de semeadura e ano agrícola) inteiramente casualizado com quatro repetições. Cada repetição consistiu de um balde de 12 litros de capacidade com 10 plantas, cinco das quais foram marcadas com arames coloridos e avaliadas quanto ao número final de folhas no colmo principal (NFF). Calculou-se o fotoperíodo acumulado na fase em que o arroz é sensível ao fotoperíodo. Foi verificado um aumento linear do NFF com o fotoperíodo acumulado em todas as cultivares, o que indica uma resposta fotoperiódica típica de planta de dia curto nos genótipos de arroz. Houve diferença de sensibilidade ao fotoperíodo entre as cultivares.

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Vieira, Elisabete Simões. "Debt policy and firm performance of family firms: the impact of economic adversity." International Journal of Managerial Finance 13, no. 3 (June 5, 2017): 267–86. http://dx.doi.org/10.1108/ijmf-03-2016-0062.

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Purpose The purpose of this paper is to analyse the relationship between debt policy and performance among family firms (FF), providing evidence on whether FF differ from non-family firms (NFF). It also focusses on the possibility of asymmetrical debt policy impact on performance between periods of stability and economic adversity. Design/methodology/approach The paper employs panel data regression, considering a sample of Portuguese listed firms for the period between 1999 and 2014. Findings Overall, the author find evidence that debt contributes negatively to firms’ performance, which is consistent with the pecking order prediction, and that the relationship between debt and performance do not differ significantly between FF and NFF. After addressing the endogeneity issue, the author conclude that firms’ performance is negatively influenced by both short- and long-term debt. Considering the total debt, the negative relationship between the two variables differs from family and non-family companies. The results show that age and size influences positively, and the independence of the board directors influences negatively the firms’ performance. The empirical findings suggest that under economic adversity, the firms’ performance is negatively affected. Finally, the author conclude that return on assets appear to fit better than return on equity or MB when you want to relate debt and firm performance. Research limitations/implications A limitation of this study is the small size of the Euronext Lisbon that results in a small sample. Originality/value This paper offers some insights on the relationship between debt policy and firm performance from a country with weak protection of minority shareholders, concentrated ownership and a significant family control. It also gives the opportunity to analyse whether firm performance differs according to market conditions.

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Pelham, Jonathan G., and Chris Hockley. "Analysis of Short form Maintenance Records for NFF Using NLP, Phrase Matching, and Bayesian Learning." Procedia CIRP 59 (2017): 257–62. http://dx.doi.org/10.1016/j.procir.2016.10.123.

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Zhong-Wu, Zhang, and Ren Shi-Wei. "Molecular field theory analysis of the relation between nFF, MFe2(0) and Tc in RTC." Journal of Magnetism and Magnetic Materials 151, no. 1-2 (November 1995): 82–86. http://dx.doi.org/10.1016/0304-8853(95)00400-9.

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Fukaura, Junichi, Tetsuji Tetsushi, Hideo Kaneko, Takeshi Nanba, and Yasuhiko Takeda. "Verification of the functional effect of upright pelvis fixed support system dining chair with independence support function corresponding to eating and drinking trouble of the elderly." Asploro Journal of Biomedical and Clinical Case Reports 2, no. 2 (July 22, 2019): 9–14. http://dx.doi.org/10.36502/2019/asjbccr.6153.

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Information on smooth swallowing posture and swallowing function training is described in the medical literature. A dining chair was developed in Japan to protect the elderly from aspiration and aspiration pneumonia. We thought that if the function effect of the dining chair was actually exhibited, it would be vital information to all the elderly whose swallowing function continues to decline. We tried the verification test with electromyograph about the actual functional effect of the developed dining chair. Eating with the neck forward flexion (NFF) posture by the upright pelvis fixed support has shown a smooth swallowing effect which can be valuable information to elderly people around the world, whose swallowing function continues to decline.

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Bagryanskaya, Irina Yu, Yuri V. Gatilov, Alexey O. Miller, Makhmut M. Shakirov, and Andrey V. Zibarev. "Regioselectivity of fluoride ion-induced intramolecular nucleophilic cyclization of heptafluoronaphthyl sulfur diimides 2?NfF?N?S?N?SiMe3 and 2?NfFS?N?S?N?S1Me3." Heteroatom Chemistry 5, no. 5-6 (September 1994): 561–65. http://dx.doi.org/10.1002/hc.520050523.

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Fedrick, Vimbai, Paul Phillips, and Chris Hockley. "The Contribution of Test and Analysis to the No Fault Found (NFF) Issue within the UK MOD." Procedia CIRP 11 (2013): 80–85. http://dx.doi.org/10.1016/j.procir.2013.07.058.

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Suciati, F. K., and E. Suwondo. "Evaluation and Improvement of Unscheduled Removal Component Reliability Calculation Method with No Fault Found (NFF) Shop Finding Results." IOP Conference Series: Materials Science and Engineering 645 (October 28, 2019): 012007. http://dx.doi.org/10.1088/1757-899x/645/1/012007.

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Hamoy-Jimenez, Geohana, Raymond Kim, Suganth Suppiah, Gelareh Zadeh, Vera Bril, and Carolina Barnett. "Quality of life in patients with neurofibromatosis type 1 and 2 in Canada." Neuro-Oncology Advances 2, Supplement_1 (January 10, 2020): i141—i149. http://dx.doi.org/10.1093/noajnl/vdaa003.

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Abstract Background There is scarce data on the quality of life of people with neurofibromatosis type 1 (NF1) and type 2 (NF2) in Canada. Methods A cross-sectional study of adults with NF1 and NF2 attending a tertiary center. Patients completed generic measures (SF-36, EQ-5D-5L, and PROMIS pain interference) and disease-specific questionnaires (PedsQL NF1 module and the NFTI-QOL for NF2). We compared generic scores between NF1 and NF2 individuals and used regression models to assess factors associated with quality of life. Results Hundred and eighty-four participants were enrolled. Mean age was 33 years in NF1 and 40 years in NF2. NF1 and NF2 individuals had lower employment rates and lower scores in all domains of the SF-36 compared to the general Canadian population (P < .005). Using the EQ-5D-5L, there was a high proportion of pain (64% in NF1 and 74% in NF2) and anxiety/depression (60% in NF1 and 68% in NF2). Pain interference correlated with poor quality of life in NF1 and NF2; perceived physical appearance was the main predictor of mental well-being in NF1. Conclusions Individuals with NF1 and NF2 have low quality of life, and this correlates with pain, anxiety, and depression, which are prevalent in NF1 and NF2. Perceived physical appearance predicts quality of life in NF1. A multidisciplinary approach is necessary for patients with NF1 and NF2, including mental health and pain management.

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Haase, A. T., M. K. Jenkins, H. Peng, and K. Urdahl. "nef-naf nexus?" Current Biology 2, no. 3 (March 1992): 130–32. http://dx.doi.org/10.1016/0960-9822(92)90249-a.

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BAGRYANSKAYA, I. YU, YU V. GATILOV, A. O. MILLER, M. M. SHAKIROV, and A. V. ZIBAREV. "ChemInform Abstract: Cyclic Aryleneazachalcogenenes. Part 8. Regioselectivity of Fluoride Ion-Induced Intramolecular Nucleophilic Cyclization of Heptafluoronaphthyl Sulfur Diimides 2-NfF-N=S=N-SiMe3 and 2-NfFS-N=S=N- SiMe3." ChemInform 26, no. 36 (August 17, 2010): no. http://dx.doi.org/10.1002/chin.199536053.

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Murovic, Judith A., Daniel H. Kim, and David G. Kline. "Neurofibromatosis-associated nerve sheath tumors." Neurosurgical Focus 20, no. 1 (January 2006): 1–10. http://dx.doi.org/10.3171/foc.2006.20.1.2.

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In this paper the authors describe a patient with neurofibromatosis Type 1 (NF1) who presented with sequelae of this disease. They also review the current literature on NF1 and NF2 published between 2001 and 2005. The method used to obtain information for the case report consisted of a family member interview and a review of the patient's chart. For the literature review the authors used the search engine Ovid Medline to identify papers published on the topic between 2001 and 2005. Neurofibromatosis Type 1 appears in approximately one in 2500 to 4000 births, is caused by a defect on 17q11.2, and results in neurofibromin inactivation. The authors reviewed the current literature with regard to the following aspects of this disease: 1) diagnostic criteria for NF1; 2) criteria for other NF1-associated manifestations; 3) malignant peripheral nerve sheath tumors (PNSTs); 4) the examination protocol for a patient with an NF1-related NST; 5) imaging findings in patients with NF1; 6) other diagnostic studies; 7) surgical and adjuvant treatment for NSTs and malignant PNSTs; and 8) hormone receptors in NF1-related tumors. Pertinent illustrations are included. Neurofibromatosis Type 2 occurs much less frequently than NF1, that is, in one in 33,000 births. Mutations in NF2 occur on 22q12 and result in inactivation of the tumor suppressor merlin. The following data on this disease are presented: 1) diagnostic criteria for NF2; 2) criteria for other NF2 manifestations; 3) malignant PNSTs in patients with NF2; 4) examination protocol for the patient with NF2 who has an NST; and 5) imaging findings in patients with NF2. Relevant illustrations are included. It is important that neurosurgeons be aware of the sequelae of NF1 and NF2, because they may be called on to treat these conditions.

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op den Brouw, Bianca, Parviz Ghezellou, Nicholas R. Casewell, Syed Abid Ali, Behzad Fathinia, Bryan G. Fry, Mettine H. A. Bos, and Maria P. Ikonomopoulou. "Pharmacological Characterisation of Pseudocerastes and Eristicophis Viper Venoms Reveal Anticancer (Melanoma) Properties and a Potentially Novel Mode of Fibrinogenolysis." International Journal of Molecular Sciences 22, no. 13 (June 27, 2021): 6896. http://dx.doi.org/10.3390/ijms22136896.

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Venoms are a rich source of potential lead compounds for drug discovery, and descriptive studies of venom form the first phase of the biodiscovery process. In this study, we investigated the pharmacological potential of crude Pseudocerastes and Eristicophis snake venoms in haematological disorders and cancer treatment. We assessed their antithrombotic potential using fibrinogen thromboelastography, fibrinogen gels with and without protease inhibitors, and colourimetric fibrinolysis assays. These assays indicated that the anticoagulant properties of the venoms are likely induced by the hydrolysis of phospholipids and by selective fibrinogenolysis. Furthermore, while most fibrinogenolysis occurred by the direct activity of snake venom metalloproteases and serine proteases, modest evidence indicated that fibrinogenolytic activity may also be mediated by selective venom phospholipases and an inhibitory venom-derived serine protease. We also found that the Pseudocerastes venoms significantly reduced the viability of human melanoma (MM96L) cells by more than 80%, while it had almost no effect on the healthy neonatal foreskin fibroblasts (NFF) as determined by viability assays. The bioactive properties of these venoms suggest that they contain a number of toxins suitable for downstream pharmacological development as candidates for antithrombotic or anticancer agents.

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Moral-Sanz, Javier, Manuel A. Fernandez-Rojo, Jeremy Potriquet, Pamela Mukhopadhyay, Andreas Brust, Patrick Wilhelm, Taylor B. Smallwood, et al. "ERK and mTORC1 Inhibitors Enhance the Anti-Cancer Capacity of the Octpep-1 Venom-Derived Peptide in Melanoma BRAF(V600E) Mutations." Toxins 13, no. 2 (February 14, 2021): 146. http://dx.doi.org/10.3390/toxins13020146.

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Melanoma is the main cause of skin cancer deaths, with special emphasis in those cases carrying BRAF mutations that trigger the mitogen-activated protein kinases (MAPK) signaling and unrestrained cell proliferation in the absence of mitogens. Current therapies targeting MAPK are hindered by drug resistance and relapse that rely on metabolic rewiring and Akt activation. To identify new drug candidates against melanoma, we investigated the molecular mechanism of action of the Octopus Kaurna-derived peptide, Octpep-1, in human BRAF(V600E) melanoma cells using proteomics and RNAseq coupled with metabolic analysis. Fluorescence microscopy verified that Octpep-1 tagged with fluorescein enters MM96L and NFF cells and distributes preferentially in the perinuclear area of MM96L cells. Proteomics and RNAseq revealed that Octpep-1 targets PI3K/AKT/mTOR signaling in MM96L cells. In addition, Octpep-1 combined with rapamycin (mTORC1 inhibitor) or LY3214996 (ERK1/2 inhibitor) augmented the cytotoxicity against BRAF(V600E) melanoma cells in comparison with the inhibitors or Octpep-1 alone. Octpep-1-treated MM96L cells displayed reduced glycolysis and mitochondrial respiration when combined with LY3214996. Altogether these data support Octpep-1 as an optimal candidate in combination therapies for melanoma BRAF(V600E) mutations.

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Bettegowda, Chetan, Meena Upadhayaya, D. Gareth Evans, AeRang Kim, Dimitrios Mathios, and Clemens O. Hanemann. "Genotype-Phenotype Correlations in Neurofibromatosis and Their Potential Clinical Use." Neurology 97, no. 7 Supplement 1 (July 6, 2021): S91—S98. http://dx.doi.org/10.1212/wnl.0000000000012436.

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ObjectiveBecause clinically validated biomarkers for neurofibromatosis 1 (NF1) and neurofibromatosis 2 (NF2) have not been identified, we aimed to determine whether genotype-phenotype correlations are useful in clinical trials in NF1 and NF2.MethodsThe Response Evaluation in Neurofibromatosis and Schwannomatosis (REiNS) Biomarker Group first performed a systematic literature search and reviewed existing data on genetic biomarkers in NF1 and NF2 and in in malignant peripheral nerve sheath tumors. The group then met during a series of consensus meetings to develop a joint report.ResultsWe found that in NF2, the genetic severity score is clearly of potential clinical use. In NF1, despite over 3,000 constitutional variants having been described in the NF1 gene, only 4 actionable genotype-phenotype correlations exist. The diagnosis and treatment decision of these tumors should ideally include histopathology and compilation of some of the genetic markers.ConclusionWe summarized emerging clinical use of genotype-phenotype correlations in neurofibromatosis.

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Journal articles on the topic 'NFF'

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