Log in

Relevant bibliographies by topics / Newborn survival / Journal articles

Journal articles on the topic 'Newborn survival'

To see the other types of publications on this topic, follow the link: Newborn survival.

Author: Grafiati

Published: 10 December 2022

Last updated: 28 January 2023

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'Newborn survival.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Castle, Valerie, Geoffrey Coates, Lesley G. Mitchell, Hugh O’Brodovich, and Maureen Andrew. "The Effect of Hypoxia on Platelet Survival and Site of Sequestration in the Newborn Rabbit." Thrombosis and Haemostasis 59, no. 01 (1988): 045–48. http://dx.doi.org/10.1055/s-0038-1642563.

Full text

Abstract:

SummaryThrombocytopenia occurs frequently in sick neonates that have experienced perinatal asphyxia. This study investigated the effect of one component of asphyxia, hypoxia, on platelet life-span and site of sequestration. 11 indium oxine platelet survivals with scintigraphic imaging were performed in newborn and adult rabbits exposed to room air (normoxia) or following exposure to a 15 minute, severe hypoxic insult (FjOa = 0.05). Platelet survivals in normoxic adults (n = 27) and newborn rabbits (n = 11) were similar (60 ± 3.9 hr vs 64 ± 8.0 hr, m ± SEM). Inhalation of 5% oxygen for 15 minutes was not associated with an acidemia and did not produce thrombocytopenia but significantly shortened the platelet survival to 34 ± 3 hr in the adult (n = 18) and 38 ± 3 hr in the newborn rabbit (n = 7). Postmortem measurement of the sites of mIn-platelet accumulation showed that under normoxic conditions the platelets accumulated in the liver and spleen (23 ±4.3% and 8 ± 1.0% of the total body counts) in the adult with even greater accumulation in the liver (58 ± 6.8%) and spleen (19 ± 4.9%) of the newborn (p <0.001). The latter observation was likely due to the relatively increased size of the liver and spleen in the newborn compared to the adult. Hypoxia did not alter the site of platelet sequestration in adults or newborns. Our results suggest that the newborn has the same platelet survival as the adult and that acute, severe hypoxia significantly shortens the survival of platelets in both groups. Although the sites of sequestration are qualitatively the same in the newborn, there is greater sequestration in the liver and spleen when compared to the adult.

APA, Harvard, Vancouver, ISO, and other styles

2

Darmstadt, Gary L., Jeremy Shiffman, and Joy E. Lawn. "Advancing the newborn and stillbirth global agenda: priorities for the next decade." Archives of Disease in Childhood 100, Suppl 1 (January 22, 2015): S13—S18. http://dx.doi.org/10.1136/archdischild-2013-305557.

Full text

Abstract:

Remarkable advances have been made over the past decade in defining the burden of newborn mortality and morbidity and stillbirths, and in identifying interventions to address the major risk factors and causes of deaths. However, progress in saving newborn lives and preventing stillbirths in countries lags behind that for maternal mortality and for children aged 1–59 months. To accelerate progress, greater focus is needed on improving coverage, quality and equity of care at birth—particularly obstetric care during labour and childbirth, and care for small and sick newborns, which gives a triple return on investment, reducing maternal and newborn lives as well as stillbirths. Securing national-level political priority for newborn health and survival and stillbirths, and implementation of the Every Newborn Action Plan are critical to accomplishing the unfinished global agenda for newborns and stillbirths beyond 2015.

APA, Harvard, Vancouver, ISO, and other styles

3

Nadeem, Amraha, Hitesh Deshmukh, Jerilyn Gray, and Timothy Wang. "Intestinal commensal bacteria promote AT2 self-renewal and AT1 differentiation in an IL-22 dependent fashion and prepare the newborn to fight potentially fatal respiratory pathogens." Journal of Immunology 204, no. 1_Supplement (May 1, 2020): 225.30. http://dx.doi.org/10.4049/jimmunol.204.supp.225.30.

Full text

Abstract:

Abstract We demonstrated that disruption of intestinal commensal bacteria with antibiotics (ABX) severely diminished the levels of cytokine interleukin (IL)-22 in the newborn lung and rendered the ABX-exposed newborn mice susceptible post challenge with Streptococcus pneumoniae (S. pneumoniae). These experimental data suggest that colonization by intestinal commensal bacteria is vital for newborn’s lung defense against respiratory pathogens. Pregnant mouse dams were treated with ABX, and newborn mice were challenged with intratracheal S. pneumoniae (on postnatal day 5). Lungs were harvested and stained. AT2 cells and fibroblast harvested from ABX-treated or ABX-free newborn mice were cultured in matrigel to generate alveolar organoids. After harvest, the organoids were stained. To test the role of IL-22 signaling, Il22rafl/fl mice were bred with SftpcCreERT2 mice. The progeny was treated with tamoxifen and then challenged with S. pneumoniae. We found increased alveolar injury, loss of AT1 cells and reduced the frequency of proliferating AT2 cells in ABX-treated newborn mice compared to ABX-free newborn mice post-challenge with S. pneumoniae. Reconstitution of intestinal commensal bacteria or treatment with recombinant IL-22 restored the numbers of proliferating AT2 cells, reduced the injury score, and improved survival in ABX-treated newborn mice. Organoids derived ABX-exposed newborns demonstrated reduced growth and diminished AT1 differentiation. Using a developmentally appropriate and clinically relevant model, we report that intestinal commensal bacteria promote AT2 self-renewal and AT1 differentiation in an IL-22 dependent fashion, thus preparing the newborn to fight potentially fatal respiratory pathogens.

APA, Harvard, Vancouver, ISO, and other styles

4

Qazi, Mahvish, Najmus Saqib, and Rohit Raina. "Knowledge regarding prevention of hypothermia in newborns among mothers in Northern India." International Journal of Research in Medical Sciences 7, no. 5 (April 26, 2019): 1727. http://dx.doi.org/10.18203/2320-6012.ijrms20191666.

Full text

Abstract:

Background: Neonatal hypothermia is increasingly recognized as a risk factor for newborn survival. World Health Organization (WHO) recommends maintaining a warm chain and skin-to-skin care for thermo-protection of newborn children. Since little is known about practices related to newborn hypothermia, this study’s goal was to assess the knowledge of mothers of newborns especially LBW babies on prevention of hypothermia and to provide them the knowledge of cost-effective thermal protection measures.Methods: It was a cross-sectional study using pre-tested, pre-structured questionnaire. 108 postnatal mothers having LBW babies admitted in postnatal wards of Government Medical College, Jammu, Jammu and Kashmir, India were included in the study and analysed using SPSS version 20.Results: Out of 108 mothers, maximum mothers were of age less than 25 years (51%), 60% were from rural area, residing in nuclear family were 62%. Mothers attended hospital for confinement were 95% and 85% started breast feeding their babies. 45% had knowledge of keeping the baby warm by immediately wiping the baby and only 3% mothers had knowledge of Kangaroo Mother Care (KMC).Conclusions: Understanding and addressing community-based practices on hypothermia, prevention and management might help to improve newborn survival in resource-limited settings. Possible interventions include the implementation of skin-to-skin care in rural areas and the use of appropriate, low-cost newborn warmers to prevent hypothermia and support families in their provision of newborn thermal protection. Training family members to support mothers in the provision of thermo-protection for their newborns could facilitate these practices. Those who fail to fully attend antenatal clinics should be targeted for newborn care education.

APA, Harvard, Vancouver, ISO, and other styles

5

Niermeyer, S., A. Tobin, E. Schoen, T. Carter, and J. D. Klein. "A New Commitment to Newborn Survival." PEDIATRICS 135, no. 2 (January 5, 2015): 211–12. http://dx.doi.org/10.1542/peds.2014-3185.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

George, Caroline L. S., Kelli L. Goss, David K. Meyerholz, Fred S. Lamb, and Jeanne M. Snyder. "Surfactant-Associated Protein A Provides Critical Immunoprotection in Neonatal Mice." Infection and Immunity 76, no. 1 (October 29, 2007): 380–90. http://dx.doi.org/10.1128/iai.01043-07.

Full text

Abstract:

ABSTRACT The collectins surfactant-associated protein A (SP-A) and SP-D are components of innate immunity that are present before birth. Both proteins bind pathogens and assist in clearing infection. The significance of SP-A and SP-D as components of the neonatal immune system has not been investigated. To determine the role of SP-A and SP-D in neonatal immunity, wild-type, SP-A null, and SP-D null mice were bred in a bacterium-laden environment (corn dust bedding) or in a semisterile environment (cellulose fiber bedding). When reared in the corn dust bedding, SP-A null pups had significant mortality (P < 0.001) compared to both wild-type and SP-D null pups exposed to the same environment. The mortality of the SP-A null pups was associated with significant gastrointestinal tract pathology but little lung pathology. Moribund SP-A null newborn mice exhibited Bacillus sp. and Enterococcus sp. peritonitis. When the mother or newborn produced SP-A, newborn survival was significantly improved (P < 0.05) compared to the results when there was a complete absence of SP-A in both the mother and the pup. Significant sources of SP-A likely to protect a newborn include the neonatal lung and gastrointestinal tract but not the lactating mammary tissue of the mother. Furthermore, exogenous SP-A delivered by mouth to newborn SP-A null pups with SP-A null mothers improved newborn survival in the corn dust environment. Therefore, a lack of SP-D did not affect newborn survival, while SP-A produced by either the mother or the pup or oral exogenous SP-A significantly reduced newborn mortality associated with environmentally induced infection in SP-A null newborns.

APA, Harvard, Vancouver, ISO, and other styles

7

Prabhu, Deepa Fernandes, and Richard C. Larson. "Scaling the Maternal and Newborn Survival Initiative (MANSI)." International Journal of System Dynamics Applications 8, no. 1 (January 2019): 94–111. http://dx.doi.org/10.4018/ijsda.2019010106.

Full text

Abstract:

The infant mortality rate (IMR) and maternal mortality ratio (MMR) are unacceptably high in many parts of rural India. This article focuses on a system analysis approach to the best practices for scaling and replicating of maternal and newborn survival initiative (MANSI), a field-tested pilot program for addressing high IMRs and MMRs. A system dynamics model of the village birthing system is used to understand the resources needed for the viability of scaling or replication, is constructed and incorporated in the analysis. The MANSI program is a public and private partnership between a few key players. Implemented in the Seraikela area of India's Jharkhand state, the program has achieved a 32.7% reduction in neonatal mortality, a 26.5% reduction in IMR, and a 50% increase in hospital births, which tend to have better health outcomes for women and newborns. The authors conclude with a discussion of the prospects for and difficulties of replicating MANSI in other resource-constrained areas, not only in India but in other developing countries as well.

APA, Harvard, Vancouver, ISO, and other styles

8

Synnes, Anne R. "Use of the laboratory in prediction of outcome in the high-risk newborn." Clinical Chemistry 43, no. 1 (January 1, 1997): 243–48. http://dx.doi.org/10.1093/clinchem/43.1.243.

Full text

Abstract:

Abstract This paper reviews our ability to predict survival and neurodevelopmental outcome in the newborn period. Traditionally, prognosis is based on individual risk factors or disease states. The laboratory plays an important role in diagnosing some of these. For example, prenatal and newborn screening are important in the diagnosis of chromosomal abnormalities and inborn errors of metabolism. Abnormal bilirubin, glucose, and pH values in the newborn period are risk factors for death and abnormal neurodevelopment, and the degree of abnormality imparts additional information. Many newborns have multisystem disorders, and it is only when multiple variables are considered that outcome can be predicted. Three neonatal scores that incorporate multiple variables are discussed. Methodologic difficulties in determining outcome are reviewed and illustrated with survival and morbidity rates of very premature babies. The laboratory is one of many prognostic variables. The evaluation of how laboratory services are provided is difficult but important.

APA, Harvard, Vancouver, ISO, and other styles

9

Richard Okonkwo, Ikechukwu, Blessing Imuetinyan Abhulimhen-Iyoha, and Angela Anene Okolo. "Newborn Transport Practices: Influence on Newborn Survival in Benin City, Nigeria." American Journal of Pediatrics 6, no. 3 (2020): 346. http://dx.doi.org/10.11648/j.ajp.20200603.39.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Berkley, Seth, Mark Dybul, Tore Godal, and Anthony Lake. "Integration and innovation to advance newborn survival." Lancet 384, no. 9938 (July 2014): e22-e23. http://dx.doi.org/10.1016/s0140-6736(14)60691-7.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Horton, Richard. "Newborn survival: putting children at the centre." Lancet 365, no. 9462 (March 2005): 821–22. http://dx.doi.org/10.1016/s0140-6736(05)71015-1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Aubel, Judi. "Grandmothers — a neglected family resource for saving newborn lives." BMJ Global Health 6, no. 2 (February 2021): e003808. http://dx.doi.org/10.1136/bmjgh-2020-003808.

Full text

Abstract:

Across the globe, the well-being of newborns is significantly influenced by the knowledge and practices of family members, yet global health policies and interventions primarily focus on strengthening health services to save newborn lives. Predominant approaches to promote newborn survival in non-western cultures across the Global South are based on a western, nuclear family model and ignore the roles of caregivers within wider family systems, whose attitudes and practices are determined by culturally prescribed strategies. In this paper, I review evidence of a neglected facet of newborn care, the role and influence of senior women or grandmothers.Based on a family systems frame, I reviewed research from numerous settings in Africa, Asia and Latin America that provides insight into family roles related to newborn care, specifically of grandmothers. I identified primarily published studies which provide evidence of grandmothers’ role as culturally designated and influential newborn advisors to young mothers and direct caregivers. Research from all three continents reveals that grandmothers play similar core roles in newborn care while their culturally specific practices vary. This review supports two main conclusions. First, future newborn research should be conceptualised within a family systems framework that reflects the structure and dynamics of non-western collectivist cultures. Second, newborn interventions should aim not only to strengthen health services but also influential family caregivers, particularly grandmothers and the indigenous social support networks of which they are a part, in order to improve family-level newborn practices and save newborn lives.

APA, Harvard, Vancouver, ISO, and other styles

13

Mota-Rojas, D., J. Martinez-Burnes, D. Villanueva-Garcia, P. Roldan-Santiago, ME Trujillo-Ortega, H. Orozco-Gregorio, H. Bonilla-Jaime, and A. Lopez-Mayagoitia. " Animal welfare in the newborn piglet: a review." Veterinární Medicína 57, No. 7 (August 7, 2012): 338–49. http://dx.doi.org/10.17221/6262-vetmed.

Full text

Abstract:

The objective of this review is to integrate clinical findings and laboratory analyses in such a way to improve the welfare of newborn piglets and achieve better prognoses of neonatal viability. Deaths during the intrapartum period account for a significant proportion of pre-weaning mortality in farms worldwide. Piglets which die during parturition generally have normal size and typically lack gross lesions at post-mortem examination. However, circulatory abnormalities in the umbilical cord help in assessing piglet viability. Cord lesions can be classified as normal (adhered), oedematous, congested or haemorrhagic and should always be evaluated in perinatal deaths. The likelihood of neonatal survival decreases rapidly as the severity of umbilical cord lesions increase. The physiometabolic blood profile which includes acid-base balance, degree of dehydration, mineral balance, metabolic expenditure and gas exchange are also useful clinical elements for properly assessing neonatal viability. Neonatal survival is notably reduced when the blood pH falls below 7.0, lactate rises above 90 mg/dl, bicarbonate drops below 10 mmol/l, or the pCO<sub>2</sub> increases above 110 mm/Hg. Blood calcium is also an excellent indicator of neonatal stress when used in combination with the other parameters mentioned above. Trembling due to an imbalance in the movement of calcium in muscle is also a factor involved in neonatal mortality. Neurological function in the newborn piglet could also be evaluated by adapting the Apgar score widely used in human perinatology. Neonates with scores lower than 6 in a 10 point scale have generally lower survival rates. The two most important indicators for this vitality score are breathing latency and bradycardia. If the neonate has apnoea for more than 5 min and the cardiac frequency does not increase to more than 110 beats per minute the prognosis for survival is rather poor.  

APA, Harvard, Vancouver, ISO, and other styles

14

WHITE, ROBERT, and THOMAS WHITMAN. "Design of ICUs." Pediatrics 89, no. 6 (June 1, 1992): 1267. http://dx.doi.org/10.1542/peds.89.6.1267.

Full text

Abstract:

To the Editor.— Most newborn intensive care units (NICUs) today stand as monuments to the technology and efficiency that dramatically improved survival of premature newborns during the last two decades. Beginning as small "premie nurseries" which held five or six newborns per room, NICUs evolved in the late 70s and the early 80s into large, bright, noisy, high-tech wards housing 30, 40, or even 60 newborns. State building codes and recommendations for NICU design were formulated during this era which emphasized cleanliness and efficiency, but largely neglected the impact of the NICU environment on the premature newborns themselves.

APA, Harvard, Vancouver, ISO, and other styles

15

Demtse, Asrat G., Riccardo E. Pfister, Assaye K. Nigussie, Elizabeth M. McClure, Yirgu G. Ferede, Zelalem Tazu Bonger, Amha Mekasha, et al. "Hypothermia in Preterm Newborns: Impact on Survival." Global Pediatric Health 7 (January 2020): 2333794X2095765. http://dx.doi.org/10.1177/2333794x20957655.

Full text

Abstract:

Background. Globally, prematurity is the leading cause of neonatal mortality, and hypothermia is one of its contributing factors. The goal of this study was to determine the association between hypothermia and mortality. Methods. A prospective, multi-center, descriptive clinical study was conducted in 5 hospitals in Ethiopia. Axillary temperatures were taken at the time of admission to the newborn intensive care units (NICU) and followed during the NICU stay. Results. A total of 3852 premature neonates (<37 weeks) were admitted to the NICUs from July 2016 to May 2018. Of these infants, 1109 (28.8%) died and 2991 (79.6%) had hypothermia. Hypothermia was associated with perinatal asphyxia (89.5%), RDS (86.2%), and resuscitation at birth (82.7%). Admission temperatures in preterm newborns were inversely associated with mortality and morbidity. Conclusion. Hypothermia at admission is associated with neonatal mortality in premature neonates in Ethiopia. RDS and perinatal asphyxia were the main factors associated with hypothermia. The very high prevalence and association with mortality warrants quality improvement interventions.

APA, Harvard, Vancouver, ISO, and other styles

16

Kredatusova, G., J. Hajurka, I. Szakallova, A. Valencakova, and B. Vojtek. " Physiological events during parturition and possibilities for improving puppy survival: a review." Veterinární Medicína 56, No. 12 (December 27, 2011): 589–94. http://dx.doi.org/10.17221/4436-vetmed.

Full text

Abstract:

 Clinical examination and emergency care in newborn puppies is difficult, due to their different physiological characteristics and needs from those of adult dogs. This paper reviews the physiological events during parturition and the influence of parturition on puppy health.  

APA, Harvard, Vancouver, ISO, and other styles

17

Trainor, Theresa. "Video Review: Newborn Care: A Parent's Survival Guide." Journal of Human Lactation 13, no. 1 (March 1997): 81. http://dx.doi.org/10.1177/089033449701300138.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Keenan, W. "I177 HBB: A GOLDEN MINUTE FOR NEWBORN SURVIVAL." International Journal of Gynecology & Obstetrics 119 (October 2012): S205. http://dx.doi.org/10.1016/s0020-7292(12)60207-0.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Waiswa, Peter, and Stefan Peterson. "Home visits: a strategy to improve newborn survival." Lancet 382, no. 9905 (November 2013): 1626. http://dx.doi.org/10.1016/s0140-6736(13)62359-4.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Gupta, Rakesh, Abhishek Pandey, and Biju M. John. "Home visits: a strategy to improve newborn survival." Lancet 382, no. 9905 (November 2013): 1627. http://dx.doi.org/10.1016/s0140-6736(13)62360-0.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Lawn, Joy E., Hannah Blencowe, Shefali Oza, Danzhen You, Anne CC Lee, Peter Waiswa, Marek Lalli, et al. "Every Newborn: progress, priorities, and potential beyond survival." Lancet 384, no. 9938 (July 2014): 189–205. http://dx.doi.org/10.1016/s0140-6736(14)60496-7.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Sami, Samira, Teshome Adebabai, Heather Papowitz, Josep Vargas, and Kate Kerber. "Confronting inequality in newborn survival in South Sudan." Lancet 388, no. 10056 (October 2016): 2114. http://dx.doi.org/10.1016/s0140-6736(16)31918-3.

Full text

APA, Harvard, Vancouver, ISO, and other styles

23

The Lancet. "An open gate to newborn and child survival." Lancet 366, no. 9502 (December 2005): 1984. http://dx.doi.org/10.1016/s0140-6736(05)67794-x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

24

Sosenko, I. R., and L. Frank. "Guinea pig lung development: antioxidant enzymes and premature survival in high O2." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 252, no. 4 (April 1, 1987): R693—R698. http://dx.doi.org/10.1152/ajpregu.1987.252.4.r693.

Full text

Abstract:

Whereas guinea pigs have advanced prenatal morphological lung development, their surfactant development is not "precocious" compared with other small laboratory animals. To investigate whether maturation of the antioxidant enzyme (AOE) system coincides more closely with surfactant development or with morphological maturation, we assayed fetal guinea pig lungs at gestational days 49-69 for superoxide dismutase, catalase, and glutathione peroxidase activities. We found that elevations in pulmonary AOE occurred in parallel with increases in surfactant during the final 10-15% of gestation. Since newborn guinea pigs behave more like adult animals in their relative intolerance to hyperoxia, we explored whether prematurely delivered guinea pigs would tolerate high O2 exposure better than full-term newborns. We found that prematures have markedly improved hyperoxic tolerance compared with newborns (time at which 50% of animals died in greater than 95% O2, 6.4 days vs. 4.5 days, respectively, P less than 0.05); and (unlike newborns) premature pups are capable of mounting an elevated AOE response to hyperoxic challenge. Thus premature guinea pigs behave more like full-term newborns of other species in respect to hyperoxic tolerance, an additional precocious feature of guinea pig development.

APA, Harvard, Vancouver, ISO, and other styles

25

Var, Chivorn, Richard A. Oberhelman, Tian Shu, Supheap Leang, Ryan Duggal, Jennifer Le, and Alessandra N. Bazzano. "A Linked Community and Health Facility Intervention to Improve Newborn Health in Cambodia: The NICCI Stepped-Wedge Cluster-Randomized Controlled Trial." International Journal of Environmental Research and Public Health 17, no. 5 (February 28, 2020): 1559. http://dx.doi.org/10.3390/ijerph17051559.

Full text

Abstract:

Background: Newborn mortality in Cambodia remains high, with sepsis and complications of delayed care-seeking important contributing factors. Intervention study objectives were to improve infection control behavior by staff in health centers; improve referral of sick newborns; increase recognition of danger signs, and prompt care-seeking at an appropriate health facility; and appropriate referral for sick newborns by mothers and families of newborn infants. Methods: The stepped-wedge cluster-randomized controlled trial took place in rural Cambodia from February 2015 to November 2016. Sixteen clusters consisted of public health center catchment areas serving the community. The intervention included health center staff training and home visits to mothers by community health volunteers within 24 h of birth and on days 3 and 7 after delivery, including assessment of newborns for danger signs and counselling mothers. The trial participants included women who had recently delivered a newborn who were visited in their homes in the first week, as well as health center staff and community volunteers who were trained in newborn care. Women in their last trimester of pregnancy greater than 18 years of age were recruited and were blinded to their group assignment. Mothers and caregivers (2494) received counseling on handwashing practices, breastfeeding, newborn danger signs, and prompt, appropriate referral to facilities. Results: Health center staff in the intervention group had increased likelihood of hand washing at recommended key moments when compared with the control group, increased knowledge of danger signs, and higher recall of at least three hygiene messages. Of mother/caregiver participants at 14 days after delivery, women in the intervention group were much more likely to know at least three danger signs and to have received messages on care-seeking compared with controls. Conclusions: The intervention improved factors understood to be associated with newborn survival and health. Well-designed training, followed by regular supervision, enhanced the knowledge and self-reported behavior of health staff and health volunteers, as well as mothers’ own knowledge of newborn danger signs. However, further improvement in newborn care, including care-seeking for illness and handwashing among mothers and families, will require additional involvement from broader stakeholders in the community.

APA, Harvard, Vancouver, ISO, and other styles

26

Debere, Mesfin Kote, Damen Haile Mariam, Ahmed Ali, Amha Mekasha, and Grace J. Chan. "Survival status and predictors of mortality among low-birthweight neonates admitted to KMC units of five public hospitals in Ethiopia: Frailty survival regression model." PLOS ONE 17, no. 11 (November 10, 2022): e0276291. http://dx.doi.org/10.1371/journal.pone.0276291.

Full text

Abstract:

Background Low birth weight (LBW) and preterm birth are leading causes of under-five and neonatal mortality globally. Data about the timing of death and outcomes for LBW and preterm births are limited in Ethiopia and could be used to strengthen neonatal healthcare. This study describes the incidence of neonatal mortality rates (NMR) stratified by newborn size at birth for gestational age and identifies its predictors at five public hospitals in Ethiopia. Methods A prospective follow-up study enrolled 808 LBW neonates from March 2017 to February 2019. Sex-specific birthweight for gestational age percentile was constructed using Intergrowth 21st charts. Mortality patterns by birthweight for-gestational-age-specific survival curves were compared using the log-rank test and Kaplan-Meier survival curves. A random-effects frailty survival model was employed to identify predictors of time to death. Results Among the 808 newborns, the birthweight distribution was 3.2% <1000 g, 28.3% <1500 g, and 68.1% <2000 g, respectively. Birthweight for gestational age categories were 40.0% both preterm and small for gestational age (SGA), 20.4% term SGA, 35.4% appropriate weight for gestational age, and 4.2% large for gestational age (LGA). The sample included 242 deaths, of which 47.5% were both preterm and SGA. The incidence rate of mortality was 16.17/1000 (95% CI 14.26–18.34) neonatal-days of observation. Neonatal characteristics independently related to increased risk of time-to-death were male sex (adjusted hazards ratio [AHR] 3.21 95% CI 1.33–7.76), born preterm (AHR 8.56 95% CI 1.59–46.14), having been diagnosed with a complication (AHR 4.68 95% CI 1.49–14.76); some maternal characteristics and newborn care practices (like lack of effective KMC, AHR 3.54 95% CI 1.14–11.02) were also significantly associated with time-to-death. Conclusions High mortality rates were measured for low birthweight neonates–especially those both preterm and SGA births–even in the context of tertiary care. These findings highlight the need for improved quality of neonatal care, especially for the smallest newborns.

APA, Harvard, Vancouver, ISO, and other styles

27

Jae, Gina. "The Anticipatory Politics of Improving Childhood Survival for Sickle Cell Disease." Science, Technology, & Human Values 43, no. 6 (May 30, 2018): 1122–41. http://dx.doi.org/10.1177/0162243918778342.

Full text

Abstract:

Crediting scientific discovery for prolonging life is pervasive in biomedical histories of the genetic blood disorder, sickle cell disease. This includes the preventive strategies, such as newborn screening, that have underwritten the success of its life-extending interventions. Newborn screening is a technology that relies not only upon intact health infrastructures but also expertise and enhanced vigilance on the part of caregivers to anticipate complications while they are still open to circumvention. This paper posits that even after overcoming institutional barriers to make newborn screening equitably available, care and vigilance are resources that are themselves subject to what I term anticipatory politics, where structural conditions also stratify expectations for the future, including the affective appeal of medical innovations. This paper elaborates the paradigm of anticipatory politics through an ethnographic examination of newborn screening to connect the comprehensive care practices that have improved survival for sickle cell disease, and as the burden of mortality shifts to young adulthood, to expose how those who are resourced to care for these futures preferentially stand to benefit from preventive interventions.

APA, Harvard, Vancouver, ISO, and other styles

28

Znamenska, T. K., R. V. Marushko, O. O. Dudina, and O. V. Vorobyova. "Main trends of newborn health in Ukraine." Modern pediatrics. Ukraine, no. 2(122) (March 30, 2022): 5–14. http://dx.doi.org/10.15574/sp.2022.122.5.

Full text

Abstract:

The health of newborns creates the conditions for optimal physical and mental development of future generations. The presence of any pathology in the neonatal period may in the future lead to increased morbidity, reduced efficiency, reduced life expectancy and therefore significant economic losses. Purpose - to identify the characteristic trends in the health of newborns in Ukraine according to indicators of their physical development morbidity and mortality. Materials and methods. A retrospective analysis and assessment of the dynamics of newborn health in Ukraine in the XXI century according to state and industry statistics, perinatal audit according to the WHO methodology «MATRIX - BABIES». Methods of system approach, statistical, graphic image are applied. Results. Decrease in the number of newborns born in the institutions of the Ministry of Health of Ukraine from 387.9 thousand in 2000 up to 283.6 thousand in 2020 was accompanied by a negative trend of the generalized objective criterion of their health - an increase in the frequency of underweight children from 5.39% to 5.66%, OR with 95% CI 1.19 (1.16-1.21), respectively, with a stable excess of the number underweight over premature infants by 20.2-9.2%. At the same time, there is a positive trend in the survival of newborns in the first 168 hours of life - 99.36% and 99.7%, which is mainly due to an increase in this indicator, respectively, in newborns with body weight at birth 500-999g from 22.95% to 65.86%, OR with 95% CI 7.19 (5.9-8.7) and with a body weight of 1000-1499g from 84.43% to 91.87%, OR with 95% CI 2.12 (1.5-2.8) and an increase in the newborn health index from 72.0% in 2000 to 81.7% in 2020, OR with 95% CI 1.66 (1.64-1.58). Dynamic analysis of the frequency of sick newborns showed a consistent decrease from 272.1‰ in 2000 to 183.3‰ in 2020, OR with 95% CI 0.6 (0.59-0.61), due to the reduction of such pathologies as intrauterine hypoxia and asphyxia (from 111.67‰ up to 13.6‰), cases of growth retardation and malnutrition (from 72.67‰ to 18.3‰), birth injuries (from 34.75‰ to 20.79‰), congenital anomalies, deformities and chromosomal abnormalities (from 30.7‰ up to 26.8‰). At the same time, the negative dynamics of severe, causing disability of children, perinatal conditions - congenital pneumonia (with 3.18‰ in 2000 is alarming to 5.82‰ in 2020), sepsis of newborns (from 0.09‰ to 1.21‰, respectively), and for the period from 2010 - other violations of the cerebral status of the newborn (from 18.5‰ to 33.86‰), from 2015 - neonatal jaundice (from 31.11‰ to 49.65‰). The key markers of neonatal health - the levels of neonatal and early neonatal mortality were positive and were in 2000 and 2020, respectively 6.7‰ and 4.45‰, OR with 95% CI 0.68 (0.64-0.73), and 4.7‰ and 2.98‰, OR with 95% CI 0.65 (0.6-0.7). At the same time, according to the perinatal audit, the real level of early neonatal mortality in general was underestimated by 2.1-2.3 times and its proportional indicator was exceeded by 1.5 times among infants with body weight at birth over 1500 g. Conclusions. Systematic analysis of newborn health indicators shows that in order to strengthen it, it is advisable to optimize the quality of medical care at all levels of its provision based on a dynamic analysis of its condition. No conflict of interest was declared by the authors. Key words: newborns, weight categories, survival, morbidity, early neonatal, neonatal mortality.

APA, Harvard, Vancouver, ISO, and other styles

29

Sharma Pandey, Joshi, Rajbhandari, Kansakar, Dhakal, and Fingerhut. "Newborn Screening for Selected Disorders in Nepal: A Pilot Study." International Journal of Neonatal Screening 5, no. 2 (April 10, 2019): 18. http://dx.doi.org/10.3390/ijns5020018.

Full text

Abstract:

The prevalence of metabolic disorders in Nepal is yet unknown, although many case reports occur in literature. Heel-prick blood samples from newborns were collected on Dried Blood Spot (DBS) collection cards and tested through Tandem Mass Spectroscopy and fluorescence assays for disorders included in the Swiss neonatal screening program; two cases of hypothyroidism and one case of cystic fibrosis were identified. Thyroid stimulating hormone (TSH), immuoreactive trypsinogen (IRT), hydroxyprogesterone (OHP), tyrosine (Tyr), and octanoylcarnitine (C8) showed significant differences with gestation age. Most of the parameters were positively correlated with each other except galactose, galactose 1 phosphate uridyl transferase (GALT), and biotinidase. First and ninety-ninth percentiles in the Nepalese newborns were found to be different when compared with the Swiss newborns. Congenital hypothyroidism and cystic fibrosis are candidates to be considered for a newborn screening program in Nepal. Differences between the Nepalese and Swiss newborns in parametric values that change with gestation age can be attributed to a higher survival rate of pre-term babies in Switzerland. Others could be explained in part by early and exclusive breastfeeding in Nepalese newborns.

APA, Harvard, Vancouver, ISO, and other styles

30

Zhang, Wen, Hong-Yan Xu, Yan-Chun Zhang, and Kai-Bo Liu. "Delayed diagnosis of critical congenital heart defects predicting risk factors and survival rate in newborns in Beijing: a retrospective study." Journal of International Medical Research 49, no. 7 (July 2021): 030006052110280. http://dx.doi.org/10.1177/03000605211028028.

Full text

Abstract:

Objective To assess the prevalence and survival rate of newborns with a delayed diagnosis of critical congenital heart defects (CCHD) in Beijing. Methods This retrospective study analysed data from births between 2010 and 2017 from the Birth Defects Monitoring Network in Beijing. Newborns with CCHD were analysed according to seven categories. Statistical analyses were used to calculate the mortality rate within the first week (days 0–6) after live birth. Multivariate logistic regression analysis of survival was performed to analyse the potential risk factors for newborn mortality. Results A total of 1 773 935 perinatal newborns were screened in Beijing and 1851 newborns were diagnosed with CCHD, showing a prevalence of 10.43 per 10 000. Among the total 1851 CCHD patients, the majority (1692 of 1851; 91.41%) were identified through prenatal diagnosis, 104 of 1851 (5.62%) were diagnosed before obstetric discharge/transfer and 55 of 1851 (2.97%) were identified through delayed diagnosis. The prevalence of CCHD in newborns was 1.96 per 10 000 births. Multivariate logistic regression analysis of survival demonstrated that gestational age at delivery was the only risk factor for death within the first week after birth. Conclusions Within the first week after birth, gestational age was the only risk factor for death in newborns with CCHD.

APA, Harvard, Vancouver, ISO, and other styles

31

Harsh, Shah, Nagar Shashwat, Thomas Ebbie, and Patel Jay. "Predictive Factors Affecting Newborn Survival Admitted in Special Newborn Care Units of Tertiary Care Hospitals." International Journal of Medicine and Public Health 10, no. 4 (November 27, 2020): 184–88. http://dx.doi.org/10.5530/ijmedph.2020.4.40.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Thairu, Lucy, and Gretel Pelto. "Newborn care practices in Pemba Island (Tanzania) and their implications for newborn health and survival." Maternal & Child Nutrition 4, no. 3 (July 2008): 194–208. http://dx.doi.org/10.1111/j.1740-8709.2008.00135.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Islam, Monir. "Newborn survival – the forgotten milestone for achieving MDG 4." WHO South-East Asia Journal of Public Health 1, no. 3 (2012): 227. http://dx.doi.org/10.4103/2224-3151.207017.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Wada, Kazuko. "Our challenges for the Intact Survival of Newborn Babies." Perinatology 28, no. 1 (2017): 1. http://dx.doi.org/10.14734/pn.2017.28.1.1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

35

Démant, P., P. Iványi, and Eva Ivašková. "PROLONGED SURVIVAL OF MATERNAL SKIN GRAFTS IN NEWBORN RABBITS." Annals of the New York Academy of Sciences 129, no. 1 (December 16, 2006): 234–40. http://dx.doi.org/10.1111/j.1749-6632.1966.tb12854.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Savage, Felicity, Mary J. Renfrew, and Ruth M. Bland. "Countdown to 2015 for maternal, newborn, and child survival." Lancet 372, no. 9636 (August 2008): 369. http://dx.doi.org/10.1016/s0140-6736(08)61147-2.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Fenton, Paul M. "Countdown to 2015 for maternal, newborn, and child survival." Lancet 372, no. 9636 (August 2008): 369. http://dx.doi.org/10.1016/s0140-6736(08)61148-4.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Lawn, JE, K. Kerber, C. Enweronu-Laryea, and O. Massee Bateman. "Newborn survival in low resource settings-are we delivering?" BJOG: An International Journal of Obstetrics & Gynaecology 116 (September 4, 2009): 49–59. http://dx.doi.org/10.1111/j.1471-0528.2009.02328.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Darmstadt, G. L., D. A. Oot, and J. E. Lawn. "Newborn survival: changing the trajectory over the next decade." Health Policy and Planning 27, suppl 3 (June 12, 2012): iii1—iii5. http://dx.doi.org/10.1093/heapol/czs054.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Teach, Stephen J., Cedric J. Priebe, and Nicholas G. Guerina. "Survival Following Congenital Clostridial Sepsis in a Premature Newborn." Clinical Pediatrics 33, no. 12 (December 1994): 746–48. http://dx.doi.org/10.1177/000992289403301208.

Full text

APA, Harvard, Vancouver, ISO, and other styles

41

Roig, Manuel, Miguel A. Hernández, and Salvador Salcedo. "Survival from Symptomatic Nemaline Myopathy in the Newborn Period." Pediatric Neurosurgery 13, no. 2 (1987): 95–97. http://dx.doi.org/10.1159/000120310.

Full text

APA, Harvard, Vancouver, ISO, and other styles

42

Bhakoo, O. N. "Can we improve survival of the newborn in India?" Indian Journal of Pediatrics 53, no. 6 (November 1986): 674–76. http://dx.doi.org/10.1007/bf02748550.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Sharma, G., and S. Pandey. "Beyond the Rhetoric: Maternal, Newborn and Child Survival in Nepal." Nepal Journal of Obstetrics and Gynaecology 10, no. 2 (January 15, 2016): 67–72. http://dx.doi.org/10.3126/njog.v10i2.14343.

Full text

Abstract:

Nepal has performed exceptionally in improving reproductive, maternal and child health outcomes over the past two decades. In this article, we discuss these achievements and outline a vision for the future of maternal, newborn and child survival in Nepal after the era of the Millennium Development Goals. On the pathway towards quality universal health care services for all, we propose strengthening of health information systems, gradual health system reforms, improvement of existing facility based services, development of integrated service delivery models, improved technical and managerial capacity at district and facility levels. Elimination of all preventable causes of maternal, newborn and child deaths in Nepal should be our collective aspirational goal.

APA, Harvard, Vancouver, ISO, and other styles

44

Carreira, Bruno P., Daniela F. Santos, Ana I. Santos, Caetana M. Carvalho, and Inês M. Araújo. "Nitric Oxide Regulates Neurogenesis in the Hippocampus following Seizures." Oxidative Medicine and Cellular Longevity 2015 (2015): 1–14. http://dx.doi.org/10.1155/2015/451512.

Full text

Abstract:

Hippocampal neurogenesis is changed by brain injury. When neuroinflammation accompanies injury, activation of resident microglial cells promotes the release of inflammatory cytokines and reactive oxygen/nitrogen species like nitric oxide (NO). In these conditions, NO promotes proliferation of neural stem cells (NSC) in the hippocampus. However, little is known about the role of NO in the survival and differentiation of newborn cells in the injured dentate gyrus. Here we investigated the role of NO following seizures in the regulation of proliferation, migration, differentiation, and survival of NSC in the hippocampus using the kainic acid (KA) induced seizure mouse model. We show that NO increased the proliferation of NSC and the number of neuroblasts following seizures but was detrimental to the survival of newborn neurons. NO was also required for the maintenance of long-term neuroinflammation. Taken together, our data show that NO positively contributes to the initial stages of neurogenesis following seizures but compromises survival of newborn neurons.

APA, Harvard, Vancouver, ISO, and other styles

45

Gathara, David, George Serem, Georgina A. V. Murphy, Nancy Abuya, Rose Kuria, Edna Tallam, and Mike English. "Quantifying nursing care delivered in Kenyan newborn units: protocol for a cross-sectional direct observational study." BMJ Open 8, no. 7 (July 2018): e022020. http://dx.doi.org/10.1136/bmjopen-2018-022020.

Full text

Abstract:

IntroductionIn many African countries, including Kenya, a major barrier to achieving child survival goals is the slow decline in neonatal mortality that now represents 45% of the under-5 mortality. In newborn care, nurses are the primary caregivers in newborn settings and are essential in the delivery of safe and effective care. However, due to high patient workloads and limited resources, nurses may often consciously or unconsciously prioritise the care they provide resulting in some tasks being left undone or partially done (missed care). Missed care has been associated with poor patient outcomes in high-income countries. However, missed care, examined by direct observation, has not previously been the subject of research in low/middle-income countries.Methods and analysisThe aim of this study is to quantify essential neonatal nursing care provided to newborns within newborn units. We will undertake a cross-sectional study using direct observational methods within newborn units in six health facilities in Nairobi City County across the public, private-for-profit and private-not-for-profit sectors. A total of 216 newborns will be observed between 1 September 2017 and 30 May 2018. Stratified random sampling will be used to select random 12-hour observation periods while purposive sampling will be used to identify newborns for direct observation. We will report the overall prevalence of care left undone, the common tasks that are left undone and describe any sharing of tasks with people not formally qualified to provide care.Ethics and disseminationEthical approval for this study has been granted by the Kenya Medical Research Institute Scientific and Ethics Review Unit. Written informed consent will be sought from mothers and nurses. Findings from this work will be shared with the participating hospitals, an expert advisory group that comprises members involved in policy-making and more widely to the international community through conferences and peer-reviewed journals.

APA, Harvard, Vancouver, ISO, and other styles

46

Hewish, Alexandra, Michael Dibley, and Tanvir Huda. "The Neonatal Mortality Risk of Different Types of Vulnerable Newborns in Rural Bangladesh: A Prospective Cohort Study Within the Shonjibon Trial." Current Developments in Nutrition 6, Supplement_1 (June 2022): 663. http://dx.doi.org/10.1093/cdn/nzac061.047.

Full text

Abstract:

Abstract Objectives We aimed to estimate the prevalence and neonatal mortality risks associated with mutually exclusive vulnerable newborn phenotypes in rural Bangladesh. Methods We conducted a prospective cohort study in five rural districts in Bangladesh using data collected on births in the Shonjibon Trial from 2013–2015. We estimated the prevalence of preterm birth, low birth weight (LBW), small-for-gestational-age (SGA), and large-for-gestational-age (LGA) individually and for mutually exclusive phenotypes using a combination of these characteristics. We calculated the neonatal mortality associated with preterm birth, LBW, SGA, LGA, and mutually exclusive phenotypes using Kaplan-Meier survival analysis for neonatal mortality rates and Poisson regression for adjusted relative risks (aRR) with 95% confidence intervals (CI). Results We analyzed 24,314 live births and found the prevalence of preterm birth was 26.2%, LBW 22.9%, SGA 41.7%, and LGA 8.2%. The neonatal mortality risk was approximately 3-fold for preterm birth, LBW, and LGA, and 1.5-fold higher for SGA compared to newborns with appropriate-for-gestational-age (AGA), with term gestation (≥37 weeks) and normal birth weight (NBW, ≥2500g). The risk of neonatal mortality was highest in infants born SGA, preterm, and LBW (aRR = 6.3 95% CI 4.1–9.6) relative to AGA, term, and NBW infants. There was an increased mortality risk for vulnerable newborns whose households had any iron in their drinking water. Conclusions In rural Bangladesh, most infants are born with one or more vulnerable newborn characteristics associated with an increased risk of neonatal mortality. Groundwater iron may exacerbate this risk. Our findings highlight the value of categorizing infants using mutually exclusive vulnerable newborn phenotypes and their different neonatal mortality risks, which will help to target nutrition interventions to improve child survival. Funding Sources National Health and Medical Research Council, Australia.

APA, Harvard, Vancouver, ISO, and other styles

47

Belabbas, Rafik, Maria de la Luz García, Hacina AinBaziz, Ali Berbar, and Maria José Argente. "Litter size components traits in two Algerian rabbit lines." World Rabbit Science 29, no. 1 (March 31, 2021): 51. http://dx.doi.org/10.4995/wrs.2021.14247.

Full text

Abstract:

<p>The aim of this study was to estimate the limiting litter size components in rabbit females from a Synthetic line (n=32) and a Local population (n=34). Ovulation rate, number of implanted and live embryos were counted by laparoscopy at 12 d after mating. Prolificacy (total newborn, number born alive and mortality) and embryonic, foetal and prenatal survival at day of birth of the 3<sup>rd</sup> gestation were measured. The analysed traits were body weight of the female at mating, ovulation rate, implanted, live and resorbed embryos, embryonic, foetal and prenatal survival, as well as total newborn, number born alive and mortality at birth. Synthetic line females had a higher ovulation rate compared to the Local population (11.03±0.23 vs. 8.41±0.23 corpora lutea; <em>P</em><0.0001). Synthetic line displayed a higher number of implanted embryos (10.00±0.25 vs. 7.85±0.25 embryos; <em>P</em><0.0001). No difference was found between groups for number of resorbed embryos. Similar embryonic, foetal and prenatal survival rates were reported between the Synthetic line and the Local population. Additionally, total newborn was higher in the Synthetic line than in the Local population (+1.46 kits; <em>P</em><0.05). A principal components analysis was performed. The first four principal components (PC) explained more than 90% of the total variation in both lines. Total newborn, number born alive and live embryos were the main variables defining the 1<sup>st</sup> PC. Resorbed embryos and foetal survival were located in the 2<sup>nd</sup> PC. Ovulation rate and embryonic survival were the predominant variables defining the 3<sup>rd</sup> PC. The body weight of females was located in the 4<sup>th</sup> PC. The phenotypic correlation between total newborn and its components were high and positive in both lines, except for ovulation rate and total newborn, where it was moderate in Synthetic line. In conclusion, the females from Synthetic line have a higher total newborn than those from Local population, as a consequence of a higher number of released oocytes and embryos that successfully reach implantation. However, a higher uterine crowding in Synthetic line seems to limit survival of foetuses that reach term of gestation, while ovulation rate is the principal limiting factor of total newborn in Local population.</p>

APA, Harvard, Vancouver, ISO, and other styles

48

Quinn, Charles T., Zora R. Rogers, and George R. Buchanan. "Survival of children with sickle cell disease." Blood 103, no. 11 (June 1, 2004): 4023–27. http://dx.doi.org/10.1182/blood-2003-11-3758.

Full text

Abstract:

Abstract Contemporary survival data are not available for children with sickle cell disease (SCD). The few previous childhood SCD cohort studies do not reflect the benefits of modern therapy. We defined an inception cohort of newborns with sickle cell anemia (SS), sickle-β°-thalassemia (S β°), sickle-hemoglobin C disease (SC), or sickle-β+-thalassemia (Sβ+) who were identified by newborn screening and followed for up to 18 years. The incidence of death and stroke were calculated. Overall survival, SCD-related survival (considering only SCD-related deaths), and strokefree survival were determined. The 711 subjects provided 5648 patient-years of observation. Twenty-five subjects died; mean age at death was 5.6 years. Five patients died from infection. Thirty had at least one stroke. Among SS and Sβ° subjects (n = 448), the overall rates of death and stroke were 0.59 and 0.85/100 patient-years. Survival analysis of SS and Sβ° subjects predicted the cumulative overall, SCD-related, and stroke-free survival to be 85.6%, 93.6%, and 88.5% by 18 years of age. No SCD-related deaths or strokes occurred in SC or Sβ+ subjects (n = 263). Childhood mortality from SCD is decreasing, the mean age at death is increasing, and a smaller proportion of deaths are from infection.

APA, Harvard, Vancouver, ISO, and other styles

49

Nawara-Baran, Agnieszka. "The Prognosis for Fetuses with Vein of Galen Malformation and Symptoms of Heart Failure." Prenatal Cardiology 7, no. 1 (December 20, 2017): 83–87. http://dx.doi.org/10.1515/pcard-2017-0012.

Full text

Abstract:

Abstract Vein of Galen Malformation (VGM) it is the most common cerebral arteriovenus malformation in fetuses and children. Usually VGM causes volume overload of the heart and can induce mass effect in the brain, causing progressive neurological impairment. Modern treatment allow on earlier therapy (before the 5th monthof life). This gives the newborn with isolated VGM and heart failure a chance of survival. This work presents case of isolated vein of Galen malformation with diagnosed cardiomegaly, monophasic flow through the tricuspid valve, large right heart, pericardiac effusion, dilatation of SVC and abnormal doppler exam. Postnatal management included aggressive medical treatment of cardiac failure and early transarterial embolization of the selected vessels feeding the aneurysm at 6 days of age. The newborn is 6 month old, growing normally without neurological deficits or developmental retardation and waiting of next stage therapy. New techniques of treatment give fetuses with VGM and prenatal signs of cardiac insufficiency a chance of survival and healthy life, in a group of selected cases. The analysis of the cardiovascular system in fetuses with VGM according to uniform criteria is essential in order to assess the influence of these malformations on the survivability of newborns.

APA, Harvard, Vancouver, ISO, and other styles

50

BOYKO, N. V., G. YU MODEL, and V. I. ALEKHINA. "FEATURES OF ADAPTATION OF NEWBORNS WHO HAVE HAD INTRAUTERINE BLOOD TRANSFUSIONS." Kuban Scientific Medical Bulletin 25, no. 3 (July 26, 2018): 34–39. http://dx.doi.org/10.25207/1608-6228-2018-25-3-34-39.

Full text

Abstract:

Aim. To assess the adaptive capacity of newborns who have had intrauterine blood transfusions.Materials and methods. The study included 40 newborns who underwent intrauterine intravascular blood transfusion due to hemolytic disease of the fetus RH-factor.Results. The percentage of antenatal fetal losses in hemolytic disease is significantly reduced. Intravascular blood transfusion allowed the fetus to prolong the pregnancy for at least 32 weeks. Survival of newborns with hemolytic disease has significantly increased. Conducting intrauterine blood transfusions leads to a decrease in the frequency and multiplicity of postpartum blood transfusions.Conclusion. With timely delivery and adequate use of high-tech methods of treatment, both intrauterine and postnatal, it is possible in 88% of cases to preserve the life of the newborn with satisfactory rates of physical and neuropsychological development.

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!