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1

1948-, Priebe Waldemar, and American Chemical Society. Division of Carbohydrate Chemistry., eds. Anthracycline antibiotics: New analogues, methods of delivery, and mechanisms of action. Washington, DC: American Chemical Society, 1995.

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2

P, Rosen Barry, Mobashery Shahriar, and Symposium on Resolving the Antibiotic Paradox: Progress in Drug Design and Resistance (1997 : Wayne State University), eds. Resolving the antibiotic paradox: Progress in understanding drug resistance and development of new antibiotics. New York: Kluwer Academic/Plenum, 1998.

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3

N, Chakrabarty A., and National Institute of Science Communication (New Delhi, India), eds. Non antibiotics: A new class of unrecognised antimicrobics. New Delhi: National Institute of Science Communication, 1998.

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4

Center for Drugs and Biologics (U.S.). Guideline on formatting, assembling, and submitting new drug and antibiotic applications. Rockville, Md: Center for Drugs and Biologics, Food and Drug Administration, Department of Health and Human Services, 1987.

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5

1934-, Neu Harold C., Young Lowell S, and Zinner Stephen H. 1939-, eds. The New macrolides, azalides, and streptogramins: Pharmacology and clinical applications. New York: M. Dekker, 1993.

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6

1939-, Zinner Stephen H., and ICMASK (4th : 1998 : Barcelona, Spain), eds. New considerations for macrolides, azalides, streptogramins, and ketolides. New York: Marcel Dekker, 2000.

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7

Gray, Lynn. Antibiotic resistance: New products and strategies. Norwalk, CT: Business Communications Co., 2002.

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8

Bellido, F. The new -lactams: Mode of action, mechanisms of resistance. Basle, Switzerland: Roche, 1989.

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9

1939-, Zinner Stephen H., and International Conference on the Macrolides, Azalides, and Streptogramins (3rd : 1996 : Lisbon, Portugal), eds. Expanding indications for the new macrolides, azalides, and streptogramins. New York: Dekker, 1997.

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10

NATO, Advanced Research Workshop on a. New Model for Analyzing Antimicrobial Peptides with Biomedical Applications (2001 Prague Czech Republic). A new model for analyzing antimicrobial peptides with biomedical applications. Amsterdam: IOS Press, 2002.

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11

Champney, W. Scott, ed. New Antibiotic Targets. Totowa, NJ: Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-246-5.

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12

Scott, Champney W., ed. New antibiotic targets. Totowa, N.J: Humana Press, 2008.

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13

International IMVI Essen/WHO Symposium. (2nd 1988 Essen, Germany). Progress in rabies control: Proceedings of the Second International IMVI ESSEN/WHO Symposium on "New Developments in Rabies Control", Essen, 5-7 July 1988 ; and, Report of the WHO Consultation on Rabies, Essen, 8 July 1988. Edited by Thraenhart Olaf, Universität Essen. Institute for Medical Virology and Immunology., World Health Organization, and WHO Consultation on Rabies. (1988 : Essen, Germany). Royal Tunbridge Wells, Kent: Wells Medical, 1989.

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14

A, Fisher Jeffrey. The plague makers: How we are creating catastrophic new epidemics-- and what we must do to avert them. New York: Simon & Schuster, 1994.

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15

Emerging epidemics: The menance of new infections. New York, N.Y: Penguin Books, 2010.

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16

A fierce radiance: A novel. New York: Harper, 2010.

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17

Office, General Accounting. Food safety: New initiatives would fundamentally alter the existing system : report to Congressional requesters. Washington, D.C: U.S. General Accounting Office, 1996.

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18

Center for Drugs and Biologics (U.S.), ed. Guideline on formatting, assembling, and submitting new drug and antibiotic applications. Rockville, Md: Center for Drugs and Biologics, Food and Drug Administration, Dept. of Health and Human Services, 1987.

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19

Center for Drugs and Biologics (U.S.), ed. Guideline for the format and content of the summary for new drug and antibiotic applications. Rockville, Md: Center for Drugs and Biologics, Food and Drug Administration, Dept. of Health and Human Services, 1987.

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20

Olisa, Nzedegwu Robert. Biological agents index: Quality management of infectious disease intervention programs : achieving cost-effective outcomes using macroeconomics and microbiology, in additions to new public management concepts for implementation and evaluation of best practices in community based sanitation, health promotion, large scale antibiotics and vaccines manufacturing, and laboratory analytical platforms. 3rd ed. El Paso, Tex: American Journal of Biological Defense Press, 2008.

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21

R, Kiani, Shimada K, and International Congress of Chemotherapy (15th : 1987 : Istanbul, Turkey), eds. New oral cephalosporin antibiotic--cefixime: Workshop, 15th International Congress of Chemotherapy, July 19-24, 1987, Istanbul, Turkey. Landsberg/Lech: Ecomed, 1988.

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22

F, Acar J., and Neu Harold C. 1934-, eds. Roxithromycin: A new antibiotic : posters presented at a symposium held in Paris, 29-30th May 1987, sponsored by Roussel Uclaf. London: Medical Tribune Group, 1988.

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23

Harvey, Arbit, and United States. Department of Health and Human Services., eds. Keyword guide to applications for FDA approval to market a new drug (NDA) or an antibiotic drug (21CFR-part 314). Prairie View (Ill.): Interpharm Press, 1987.

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24

Bedford, Michael R., Gary G. Partridge, Milan Hruby, and Carrie L. Walk, eds. Enzymes in farm animal nutrition. 3rd ed. Wallingford: CABI, 2022. http://dx.doi.org/10.1079/9781789241563.0000.

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Abstract This third edition explores considerable advances such as the use of enzymes in fish and shrimp diets, new understanding of how phytases function in the animal, NSPase research and enzymes' extended use in ruminant markets. This book also provides comprehensive coverage of all topics relating to the production, use, cooperativity and analysis of feed enzymes. It is fully updated throughout, revealing significant developments such as new methods to deliver enzymes (formulations, encapsulations, and liquid spray systems) and advances in enzyme analysis. It also includes brand new chapters on combinations of enzymes, antibiotic-free diets and how to measure response in feed-enzyme trials. Covering biochemistry, enzymology and characteristics relevant to animal feed use, this book forms a valuable resource for academics and students of animal nutrition and production, as well as professionals in the animal feed industry.
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25

Mills, Lester S. Synthetic approaches to the antitumour-antibiotic CC-1065: Application of a new phase transfer catalyst to oxidation : investigation of an unexpected reaction of methoxyacetyl chloride. Norwich: University of East Anglia, 1985.

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26

Franceschi, G., and S. Mitsuhashi. New Penem Antibiotics. Springer-Verlag Berlin and Heidelberg GmbH & Co. KG, 1991.

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27

Wilson, Mary E. Antibiotics. Oxford University Press, 2019. http://dx.doi.org/10.1093/wentk/9780190663414.001.0001.

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A STIRRING EXAMINATION OF A LOOMING CRISIS Virtually everyone has taken antibiotics. They can be lifesavers -- or they can be useless. But what are they? How are they used? And what happens as the effectiveness of antibiotics begins to decline? Antibiotics: What Everyone Needs to Know® examines the personal and societal implications of our planet's most important -- and arguably most overused -- medications. In a question-and-answer format, it unpacks the most complicated aspects of this issue, including: · How antibiotics are used (and overused) in humans, plants, and livestock · The consequences to date, and the potential crisis ahead, as overuse of existing antibiotics breeds new resistance in bacteria · How the globalized world enables antibiotic resistance more quickly · Collateral damage, individually and societally, of antibiotic use · The difficult decisions ahead related to medical care and the food system Grounded in the latest scientific research and translated for general readers, Antibiotics: What Everyone Needs to Know® offers a clear-eyed overview of where we are, and what the future holds, as antibiotics lose their might.
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28

Hall, James, and Allen Turner. Antibiotic Therapy: New Developments. Nova Science Publishers, Incorporated, 2013.

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29

Chemical analysis for antibiotics used in agriculture: New methodology for antibiotic residue determination. Arlington, VA: AOAC international, 1995.

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30

Rosen, Barry P. Resolving the Antibiotic Paradox: Progress in Understanding Drug Resistance and Development of New Antibiotics. Springer, 2012.

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31

Mobashery, Shahriar, and Barry P. Rosen. Resolving the Antibiotic Paradox: Progress in Understanding Drug Resistance and Development of New Antibiotics. Springer London, Limited, 2012.

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32

Firestine, Steven M., Troy Lister, Christian Melander, Ernesto Abel-Santos, and Cezar Khursigara. Antibiotic Drug Discovery: New Targets and Molecular Entities. Royal Society of Chemistry, The, 2017.

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33

The Search Of New Generations Of Antibiotics: Concern for bacterial resistance in humans. Suggesting a shift in strategy-. Wiesbaden, Germany: Progress International Verlag, 1999.

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34

Anthracycline Antibiotics in Cancer Therapy: Proceedings of the International Symposium on Anthracycline Antibiotics in Cancer Therapy, New York, New York, 16-18 September 1981. Springer Netherlands, 2012.

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35

Anthracycline Antibiotics in Cancer Therapy: Proceedings of the International Symposium on Anthracycline Antibiotics in Cancer Therapy, New York, New York, 16-18 September 1981. Springer, 2012.

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36

Muggia, Franco M., Charles W. Young, and Stephen K. Carter. Anthracycline Antibiotics in Cancer Therapy: Proceedings of the International Symposium on Anthracycline Antibiotics in Cancer Therapy, New York, New York, 16-18 September 1981. Springer, 2012.

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37

Felgueiras, Helena, ed. New Biomolecules and Drug Delivery Systems as Alternatives to Conventional Antibiotics. MDPI, 2022. http://dx.doi.org/10.3390/books978-3-0365-4735-0.

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38

Pseudomonas Aeruginosa: New Therapeutic Approaches from Basic Research (Antibiotics and Chemotherapy). S. Karger AG (Switzerland), 1985.

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39

(Editor), Barry P. Rosen, and Shahriar Mobashery (Editor), eds. Resolving the Antibiotic Paradox: Progress in Understanding Drug Resistance and Development of New Antibiotics (Advances in Experimental Medicine and Biology). Springer, 1999.

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40

Klein, Eili Y. Antibiotic Resistance. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199976805.003.0068.

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Antibacterial resistance threatens the ability of physicians to treat infections, reversing medical gains and increasing the probability of morbidity and mortality in infected patients. Decreased antibiotic efficacy also threatens advanced surgical procedures dependent on antibiotic effectiveness, such as organ and prosthetic transplants. Even simple procedures consider antibiotic prophylaxis to be a standard means of controlling surgical site infections. Despite the link between increased antibiotic use and resistance, a large fraction of antimicrobial use is inappropriate, particularly for acute respiratory tract infections. Methicillin-resistant Staphylococcus aureus (MRSA) is the most significant antibiotic-resistant pathogen, but new pathogens such as carbapenem-resistant enterobacteriaceae (CRE) are increasing in clinical significance. Antibiotic use and resistance is rising rapidly in developing countries, particularly India, China, and various African countries. The inappropriate use of antibiotics must be reduced, and incentives for the development of new antibiotics should be increased.
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41

Hopkins, Susan. The international and national challenges faced in ensuring prudent use of antibiotics. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198758792.003.0001.

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In April 2014, the World Health Organization reinforced that without urgent coordinated action by most stakeholders the world is headed for a post-antibiotic era in which common infections and minor injuries, which have been treatable for decades, could kill once again. With the rise in the number of infections due to antibiotic-resistant bacteria and the lack of development of new antibiotics, antimicrobial resistance is a major clinical and public health issue that society needs to tackle. This chapter focuses on the challenges of drug resistance and antimicrobial development together with how healthcare organizations can address this threat. A number of initiatives are discussed, including how prescribers and the public need to ensure that antimicrobials are used widely to prevent any collateral damage.
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42

1934-, Neu Harold C., and International Conference on the Macrolides, Azalides, and Streptogramins (2nd : 1994 : Venice, Italy), eds. New macrolides, azalides, and streptogramins in clinical practice. New York: M. Dekker, 1995.

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43

Priebe, Waldemar. Anthracycline Antibiotics: New Analogues, Methods of Delivery, and Mechanisms of Action (Acs Symposium Series). Oxford University Press, USA, 1995.

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44

European infectious and sexually transmitted disease diagnostic product markets: Emergence of significant new products entices new vendors. Mountain View, CA: Frost & Sullivan, 1994.

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45

Ruan, Zhi, Ye Feng, Yi-Wei Tang, Shaolin Wang, and Anne-Catrin Uhlemann, eds. New Insights Into the Transmission Dynamics and Control of Antimicrobial Resistance to Last-resort Antibiotics. Frontiers Media SA, 2022. http://dx.doi.org/10.3389/978-2-88974-883-9.

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46

Czech Republic) NATO Advanced Research Workshop on a New Model for Analyzing Antimicrobial Peptides with Biomedical Applications (2001 : Prague, Alain Beschin, and Martin Bilej. A New Model for Analyzing Antimicrobial Peptides With Biomedical Applications (Nato: Life and Behavioural Sciences, 343). Ios Pr Inc, 2002.

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47

Goffin, Eric, Laura Labriola, and Michel Jadoul. Bacterial and fungal infections in patients on peritoneal dialysis. Edited by Jonathan Himmelfarb. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0270.

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Infections specifically related to peritoneal dialysis include peritonitis on the one hand, and exit-site and tunnel infections on the other hand.The diagnosis of peritonitis rests on the classical triad of cloudy dialysate, abdominal pain, and presence of < 100 white-cells (including < 50 % polymorphonuclear cells) within the dialysate effluent. Because peritonitis is associated with high mortality and morbidity rates, empiric antibiotics should be initiated without delay, covering both Gram-positive and Gram-negative organisms. Most regimens include vancomycin or a first-generation cephalosporin for the former, and a third-generation cephalosporin or an aminoglycoside for the latter. Antibiotics are usually administered via the intraperitoneal route. Prophylaxis with an anti-fungal agent has to be considered in diabetic patients and in those who just received prolonged antibiotic administration. Cure is obtained in up to 80 % of the cases ; treatment failure however may occur with refractory or relapsing peritonitis episodes. This is especially common in fungal or fecal associated peritonitis, and will require catheter withdrawal. The incidence of peritonitis has dramatically decreased in recent years with the advent of new connectology systems, and both adequate preventive measures and improved patients’ education. Still it is not clearly documented that new biocompatible dialysate fluids have a favorable effect on peritonitis incidence.Exit-site and tunnel infections are defined by the presence of a purulent discharge around the catheter and by erythema, oedema and tenderness of the subcutaneous pathway of the catheter, respectively. Antibiotics are recommended in case of documented infection. Cuff shaving may sometimes be required, as well as catheter removal in case of unfavourable evolution.
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48

Champney, W. Scott. New Antibiotic Targets. Humana Press, 2010.

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49

Simmonds, Nicholas, and Elaine Dhouieb. Management of stable CF lung disease. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780198702948.003.0004.

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This chapter addresses the nuts and bolts of everyday management of CF lung disease. It outlines the most up-to-date recommendations to ensure lung function is optimised and remains as stable as possible, including all the latest specialist CF drugs and advancements in respiratory physiotherapy techniques. Topics covered include clinical and radiological assessments of lung disease; airway clearance techniques; inhaler device selection; inhaled therapies (including the new antibiotics and drugs targeting mucus production and clearance); oral antibiotics, including azithromycin; fungal treatment; and the new era of mutation-specific drug therapy. There is also important advice on the current recommendations for exercising and travelling with CF. Overall, this chapter provides a comprehensive overview to the busy clinician requiring the latest information on the day-to-day management of CF lung disease.
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50

Chastre, Jean. Diagnosis and management of nosocomial pneumonia. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0117.

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Quantitative culture techniques, performed before the introduction of new antibiotics, enable physicians to identify most patients who need immediate treatment for nosocomial pneumonia, and help select optimal therapy in a safe, well-tolerated manner. These techniques avoid resorting to broad-spectrum coverage of all patients with a clinical suspicion of infection, and may minimize the emergence of resistant micro-organisms in the intensive care unit. However, the full impact of this decision tree on patient outcome remains controversial. Antimicrobial therapy of patients with nosocomial pneumonia is a two-stage process. The first stage involves administering broad-spectrum antibiotics at doses maximizing bacterial killing as soon as possible to avoid inadequate treatment in patients with true bacterial pneumonia. The second stage focuses on trying to achieve this objective without overusing or abusing antibiotics. This will need the combination of a number of different steps, including commitment to focused and narrow treatment once the aetiological agents are known, switching to monotherapy after day 3, and shortening duration of therapy to 7–8 days in most patients, as dictated by the patient’s clinical response and microbiological information.
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