Dissertations / Theses on the topic 'Neurokirurgi'
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Örning, Camilla. "Konceptutveckling av en stereotaktisk huvudram för användning inom neurokirurgi." Thesis, KTH, Skolan för industriell teknik och management (ITM), 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-29584.
Full textThis report presents the development of a concept for a new stereotactic head frame for use in neurosurgery. The work has been performed at Elekta Instrument AB, which is one of the world's leading companies for the development of equipment that is used to treat cancer and other diseases of the brain. Doublebend The conclusions of the work are that the developed concept has the potential to progress into a quality product, however much work remains. Further analysis, material testing and detailed design remain as future work.
Bakke, Andersson Gro-Malvina, and Lisa Åslund. "Dokumentation av postoperativ residualurin efter neurokirurgi : En kvantitativ studie." Thesis, Uppsala universitet, Institutionen för folkhälso- och vårdvetenskap, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-253499.
Full textBroman, Carina. "Riskfaktorer för kirurgiska sårinfektioner efter neurokirurgiska sårinfektioner efter neurokirurgiska operationer : en forskningsöversikt." Thesis, Sophiahemmet Högskola, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:shh:diva-1075.
Full textLejon, Linda, and Karin Stenermark. "Utvärdering av extubationsparametrar på neurointensivvårdspatienter." Thesis, Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-27017.
Full textBackground: In the interest of patient safety it is of importance to extubate intensive care patients at the exact right moment. In the case of intensive care patients in neurocritical care special considerations have to be taken into account. Assessments done in general intensive care is not directly applicable to neurocritical care, since the neurologic injury can affect the patients ability to breathe. Objective: Through the examination of medical records this study aims to evaluate parameters that prior research has found to be conductive to a successful extubation of patients in neurocritical care. Method: A prospective study with inferential quantitative design. The study was performed in a neurocritical care ward in Sweden. The patients were included continuously as they were extubated. Medical records were examined in order to gather parameters in connection to the extubation of the 108 included neurocritical care patients. Descriptive and analytical statistics, including significance analysis, was performed using IBM SPSS Statistics 20.Result: The study showed that the parameter “secretion texture” affected the extubation outcome for the patients in neurocritical care. There was also a tendency that the level of consciousness influenced extubation outcome. The other gathered parameters concerning breathing and circulation, cough strength, swallowing function and secretion volume showed no significant differences between the groups ”successful” and ”failed” extubation. Regarding the parameters for breathing and circulation, the majority of the patients, irrespective of extubation outcome, were extubated with conditions that generally complied with established recommendations. Conclusion: Parameters concerning breathing and circulation do not predict extubation outcome in a neurocritical care setting. There was however a significant difference between the groups for the parameter secretion texture. The tendency that the level of consciousness affected extubation outcome is of clinical relevance. To increase the level of patient safety concerning extubation of neurocritical care patients further research is required to enable the intensive care nurse to make an assessment of high quality and safety.
Ekman, Jakob, and Benjamin Bernroth. "Liten tuva stjälper ofta stort lass : Bakteriell kontamination över tid av operationsinstrument vid öppen neurokirurgi." Thesis, Umeå universitet, Institutionen för omvårdnad, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-115892.
Full textBackground: Post-operative surgical site infections (SSI) cause suffering for the afflicted patient and is a great cost for the patient, the health care system and society. Intra-operative contamination of surgical instruments is one of the sources of these infections. The operating room nurse is responsible for preventing infections. Purpose: The purpose of this pilot-study was to measure the degree of bacterial contamination over time on surgical instruments used in open neurosurgery as well as to observe specific sources of contamination during this time. Method: The design was a quantitative nonexperimental observational study. The data collection took place during autumn 2015 and consisted of the sampling of specific instruments used by the surgeon during surgery after preset elapsed operating times. Bacterial culturing on these instruments was then carried out at a laboratory according to a preset routine and the degree of contamination was measured by observing the amount of colony forming units (CFU). The results are presented as changes in CFU. Results: Five operations were observed and ten bacterial culturings were conducted on ten instruments. A total of ten CFU was registered during all observations. No significant increase in the number of CFU could be observed from one to two hours of elapsed surgery (P=0,156). The amount of door openings increased from 3,4 to 9,0 and the number of personnel in the operating room increased from 5,4 to 5,8. Conclusion: Despite the small number of observations included in this study the results indicate good aseptics and minimal bacterial contamination on the surgical instruments during the first two hours of surgery. Further research with longer observations, more observations and observations on other forms of surgery is needed.
Birck, Maria, and Sofia Lindblom. "Testning av högläsning och spontantal vid neurokirurgi i vaket tillstånd : En litteraturgenomgång för att vidareutveckla de intraoperativa testmetoderna." Thesis, Uppsala universitet, Logopedi, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-272367.
Full textAwake surgery is the gold standard for treatment of low-grade gliomas nearby eloquent language areas in the brain. This method increases the possibility of radical resection while cognitive functions such as language are preserved, as the method allows for online testing of cognitive functions. Improvement of the intraoperative language tests could increase the possibility of more sensitive testing and thereby decrease the risk of postoperative language impairments. There is no international or national agreement on how intraoperative language testing should be performed. The aim of this study is to explore the possibility of developing the methods of language testing which are used today at Akademiska sjukhuset in Uppsala, focusing on reading and spontaneous speech. Therefore the authors have conducted a review of current literature. The literature review, observations of surgery and interviews with speech pathologists and neurosurgeons resulted in the development of an intraoperative reading aloud test with three tasks consisting of sentences with nonwords, sentences without nonwords and single words. The classification of the test material into different levels will allow clinicians to adapt the reading test based on each individual case. A pilot trial of the reading test was preformed. The proposed test is expected to be more comprehensive in comparison to the tests that are currently used, as it enables testing of the different reading routes described in the dual route model, a psycholinguistic reading model. Additionally, guidelines for eliciting spontaneous speech have been defined.
Andersson, Sarah. "Riskfaktorer för trycksår vid planerade neurokirurgisk operation som varar längre än fyra timmar." Thesis, Sophiahemmet Högskola, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:shh:diva-1638.
Full textEngström, Ilona, and Kristina Cederwall. "Högerhemisfäriska funktioner : En litteraturstudie om språkliga och kommunikativa funktioner i höger hemisfär och hur dessa kan testas vid neurokirurgi i vaket tillstånd." Thesis, Uppsala universitet, Logopedi, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-274999.
Full textInom neurokirurgin avser uttrycket vakenkirurgi oftast tumörkirurgi i hjärnan samtidigt som patienten är vid fullt medvetande under ingreppet. Vid Akademiska Sjukhuset i Uppsala är det standard att operera tumörer belägna i den språkligt dominanta vänstra hemisfären i vaket tillstånd medan man vid en del andra centra även förespråkar vakenkirurgi i den icke-språkligt dominanta högra hemisfären. Det är emellertid inte klarlagt vilka funktioner som i så fall bör testas och hur detta ska gå till. Ett testbatteri vid vakenkirurgi i höger hemisfär skulle behöva utvecklas likt det test som används vid tumörer i vänster hemisfär. Vakenkirurgi i höger hemisfär genomförs i dag på enstaka center i Europa. Då patienter med hjärntumörer kan ha en god prognos postoperativt är det angeläget att behålla, eller förbättra, deras livskvalitet. Denna litteraturstudies huvudsakliga syfte är att presentera vilka funktioner, viktiga för språk och kommunikation, som är lokaliserade i höger hemisfär. Studien redogör också för testning av dessa funktioner intraoperativt, efter högersidig stroke och på personer med högerhemisfäriska skador. Funktionerna är många till antalet, viktiga för att bibehålla livskvaliteten men en del även svårtestade. Enligt vår litteraturgenomgång är de funktioner som framstått som mest betydelsefulla neglekt och pragmatik med dess funktionella, sociala och kommuniktiva påverkan. Mer forskning om höger hemisfärs funktioner och hur dessa är organiserade behövs. Arbetet ämnar ligga till grund för fortsatt utveckling av vakenkirurgitest i höger hemisfär på Akademiska Sjukhuset i Uppsala.
Hånell, Anders. "Plasticity and Inflammation following Traumatic Brain Injury." Doctoral thesis, Uppsala universitet, Neurokirurgi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-146551.
Full textSanteliz, Rivas Liliana, and Emma Widnersson. "Kan omvårdnadshandlingar orsaka EEG-förändringar hos neurokirurgiska intensivvårdspatienter? : En observationsstudie." Thesis, Uppsala universitet, Institutionen för folkhälso- och vårdvetenskap, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-323741.
Full textAndersson, Malin, and Tina Sandström. "Intraoperativ språktestning genom elicitering av meningskonstruktion : Vidareutveckling av språktestförfarande vid neurokirurgi i vaket tillstånd baserat på aktuell forskning, praktiska observationer samt intraoperativ pilottestning." Thesis, Uppsala universitet, Logopedi, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-242508.
Full textMökander, Linda, and Karin Stenermark. "Extubering av neurointensivvårdspatienter." Thesis, Högskolan i Halmstad, Sektionen för hälsa och samhälle (HOS), 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-17952.
Full textBackground: Many of the patients cared for in a neurocritical unit are treated with mechanical ventilation for a longer or shorter period of time during their stay in the unit. When weaning or extubating neurocritical patients, they are sometimes assessed according to the criteria for weaning and extubation used in general intensive care patients. This can cause premature extubation, resulting in re-intubation. Aim: Describe the criteria to be assessed in neurocritical patients prior to extubation. Method: Literature review. Results and conclusion: Neurocritical patients need to fulfil a combination of criteria prior to extubation. The general criteria in terms of respiration and circulation must be taken in to consideration, as well as the patient’s level of consciousness. The patient has to be conscious enough to be able to take directions. Lastly the patient’s ability to protect the airway must be assessed by observation of cough strength, the quantities and viscosity of the secretions and the patient’s swallowing function. Further research is required to ascertain the level of consciousness required in the neurocritical patients prior to extubation and in which way the assessment is best carried out. There is also need for further research considering a standardized measurement for assessing cough strength, the quantities and viscosity of secretions and swallowing function in these patients.
Ryttlefors, Mats. "Subarachnoid Hemorrhage in the Elderly." Doctoral thesis, Uppsala universitet, Institutionen för neurovetenskap, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9504.
Full textOlivecrona, Magnus. "On severe traumatic brain injury : aspects of an intra cranial pressure-targeted therapy based on the Lund concept." Doctoral thesis, Umeå universitet, Farmakologi och klinisk neurovetenskap, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1908.
Full textZetterling, Maria. "Clinical Studies in the Acute Phase of Subarachnoid Haemorrhage." Doctoral thesis, Uppsala universitet, Neurokirurgi, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-129160.
Full textKrakau, Karolina. "Energy Balance out of Balance after Severe Traumatic Brain Injury." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-114130.
Full textHolm, Sophie, and Lena Lidén. "Smärtskattning med CPOT inom neurokirurgisk intensivvård." Thesis, Röda Korsets Högskola, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:rkh:diva-662.
Full textBackground: Sedated and unconscious patients cannot verbally communicate their pain. Pain assessment is difficult for health care professionals when behavioural pain assessment tools are not implemented. Science has shown that neurosurgical intensive care patients experienced moderate to severe pain during their stay in the intensive care unit and that this pain has been undertreated. Critical-Care Pain Observation Tool (CPOT) is a pain assessment tool recently validated in Sweden for use in the intensive care unit on uncommunicative adult patients, however, neurosurgical patients were excluded in the validation. Aim: The aim of this study was to investigate the critical care nurses perception of CPOT’s usefulness in neurosurgical intensive care. Method: Mixed-method questionnaire study. An implementation of a behavioral pain assessment tool. Result: Eleven nurses in a neurosurgical intensive care unit participated. Ten of the eleven nurses considered CPOT worth implementing. None of the nurses used any other pain assessment tool than Visual Analogic Scale (VAS) at the time of the study. Rating on a scale from 0-10, whether CPOT helped the nurses in their assessment and treatment of pain, the median score was 5. From the opened-ended question, six categories were identified: positive, simple, better than VAS, evaluation opportunity, difficult to assess and insensitive. Patients at rest scored 0-5 in CPOT, with a median of 1. In nociceptive procedures, the patients scored 0-7, with a median of 3. The maximum score in CPOT is 8. Conclusion: The critical care nurses had a positive attitude towards using CPOT in neurosurgical intensive care and they considered CPOT worth implementing. CPOT gave higher scores in nociceptive procedures than at rest. Clinical relevance: The study may result in the implementation of CPOT.
Alm, Jenny, and Per Furness. "Pupillövervakning : specialistsjuksköterskans användning inom neurokirurgisk intensivvård." Thesis, Röda Korsets Högskola, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:rkh:diva-42.
Full textBackground: Pupil monitoring is part of the neurological assessment of high relevance to the neurosurgical intensive care patients. It is also described as part of pain and sedation monitoring. Objective: To investigate how specialist nurses in neurosurgical intensive care use pupil monitoring in their work. Method: The study was conducted as a semi-structured interview study. Six nurses working in neurosurgical intensive care were interviewed. The material was analyzed and presented in terms of themes and categories. Results: The two themes that emerged were To follow the course and To evaluate reliability. To follow the course meant that the pupil monitoring was described as part of monitoring and evaluating patient status and to take, defer, and evaluate nursing interventions. Documentation and reporting of pupil monitoring proved to be very important to follow patients' progress. The theme To evaluate the reliability revealed that nurses, with the help of pupil supervision, was described to distinguish actual changes in patient status to error values because of technical problems, but also to verify whether a sense of the nurse were in line with reality. Conclusion: Our results have shown that specialist nurses in neurosurgical intensive care use pupil monitoring not only to monitor patients' status and to evaluate interventions but also to evaluate the technology and reliability of emotional influence.
Johansson, Johannes. "Thermocoagulation in Deep Brain Structures : Modelling, simulation and experimental study of radio-frequency lesioning." Licentiate thesis, Linköping : Linköping University, Department of Biomedical Engineering, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-7406.
Full textHammarbäck, Annika. "Patienters upplevelser av att vänta på en akut neurokirurgisk operation : en kvalitativ intervjustudie." Thesis, Sophiahemmet Högskola, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:shh:diva-2732.
Full textIn Sweden, neurosurgical patients are treated at six different clinics around the country. The neurosurgical clinics perform both scheduled and acute surgical procedures. At times, acute surgical procedures can be delayed and patients are forced to wait. This requires knowledge for the nurse who cares for these patients on how to treat, inform and communicate with the waiting patient. The aim of the study was to describe patients’ experiences of waiting for an acute neurosurgical procedure. A qualitative method with an inductive reasoning was selected. Semi-structured interviews were chosen as an approach for data collection. Six patients participated in individual interviews performed during the months of February through May 2016 at a neurosurgical clinic in Sweden. The collected data was analyzed with a manifest content analysis. The result of the study shows that the patients lacked information about their situation during the time they waited for surgery, which lead to in feelings of uncertainty and anxiety. Some patients felt exposed, leading to strong emotions such as loneliness, disappointment and anger. The long preoperative fast enhanced the negative feelings. Although the patients expressed feelings of anxiety and anger, they seemed to accept their situation as they understood the reasons for the long wait. They experienced the health professionals as helpful, proficient and with a positive attitude, which gained the patients trust. The conclusion of the study is the importance of patient information and communication between patient and health professionals to create a trusting relationship and well-being for patients in an exposed situation.
Ringholm, Malin, and Jäger Pia Luokkanen. "Får patienten sina kalorier? : Utvärdering av flödesschema för enteral nutrition på en neurokirurgisk intensivvårdsavdelning." Thesis, Karlstads universitet, Institutionen för hälsa och vård, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-6247.
Full textFält, Marie. "Ventrikeldränagerelaterade infektioner inom neurokirurgisk vård : en journalstudie före och efter införandet av ett åtgärdspaket." Thesis, Röda Korsets Högskola, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:rkh:diva-62.
Full textBackground: External ventricular drainage (EVD) is used within neurosurgical care for medical treatment, temporary drainage of cerebrospinal fluid (CSF) and to measure intracranial pressure. An infection related to an EVD can be life threatening and cause permanent damage to the patient. Objective: To analyze the documented differences in EVD related infections, length of hospitalization and mortality, before and after the introduction of new hygiene routines – a bundle. Method: A package with medical and nursing interventions has been developed using a breakthrough method to reduce EVD related infections. The study is quantitative and has an empirical approach. A consecutive sample of patients who received an EVD during the first half of 2008 and 2009 respectively were chosen. In total 150 patients were included in the study. The data was analyzed with descriptive and analytical statistics. Results: The EVD related infections have decreased between the two time periods. No clear correlation between which actions had a direct effect on the reduction of infections was found. Those patients that had a better adherence to the package suffered fewer infections. A prevalent correlation was found between high risk actions such as flushing the EVD and CSF leaks from the site of puncture, and subsequent infections. Conclusion: The study indicates that the EVD related infections have decreased after the implementation of the package.
Höghielm, Ylva, and Björn Stenberg. "NANDA International, ett verktyg för evidensbaserad omvårdnadsdiagnostik : en studie om identifiering av omvårdnadsdiagnoser inom neurokirurgisk och thoraxkirurgisk omvårdnad." Thesis, Röda Korsets Högskola, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:rkh:diva-84.
Full textThe aim of the study was to investigate how well the classification tool NANDA International worked to identify and elucidate the panorama of nursing diagnoses, on a neurosurgical and a thoracic surgical ward. NANDA International is an evidence-based and standardized diagnostic tool for nursing. 40 patients were studied equally distributed to each ward. The data collection followed the nurse's usual work method of patient assessment as VIPS model. Based on the course moments documentation review, observation/assessment and conversation, nursing diagnoses were identified. NANDA International proved to be a user-friendly and accurate tool for nursing diagnoses. 243 nursing diagnoses were identified distributed on 49 unique diagnoses. The two most common diagnoses were Risk for Infection and Risk for Bleeding. Previous research confirms that infection and bleeding are significant risk factors after surgery. The result shows that three of the domains in NANDA International covered the 12 unique, most appropriate nursing diagnoses. These 12 unique nursing diagnoses covered in 67% of health department nursing problems. A dozen diagnoses should be enough to identify the majority of nursing diagnoses in the current health care services. Nursing diagnosis as NANDA International is based on evidence and best practices, thus contributing to the nursing process can be implemented for the patient and nurse, uniform and safe manner. In order to clinically implement NANDA International in Swedish health care requires an adjustment to the keywords in the VIPS model for documentation.
Folkesson, Carina. "Införandet av behovsanpassad bemanning inom neurokirurgisk slutenvård.Förbättringsarbetets relation till medarbetarnas arbetstillfredsställelse, kostnader och patientsäkerhet. : ”För mig är det fantastiskt det här, jag mår jättegott”." Thesis, Högskolan i Jönköping, The Jönköping Academy for Improvement of Health and Welfare, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-18567.
Full textBackground Many patients in care suffer health damage due to adverse events in health care. A number of studies point to factors that affect patient safety, including the heavy workload, inadequate staffing and long working hours have a negative impact. In intensive care, is attention and vigilance is important to identify changes in the patient status. Several studies show that the longer the work shifts and weekly working hours are associated with increased physical and mental fatigue and the risk of reduced vigilance resulting in increased risk of adverse events. Purpose The study aims to investigate how the introduction of needs-based staffing related to employees' perception of stress, time for recovery and job satisfaction as well as costs and aspects of patient safety. Method The study was conducted using a combination of methods. Surveys were released before and one year after the introduction of the staffing model. Five focus group interviews with employees and supervisors were conducted and were analyzed by qualitative content analysis. The author has during the study served as a head nurse and participated in and observed the introduction of the new staffing model. Results The questionnaire shows that 94% of respondents consider that they have time to recover every day or week after the introduction of the new model compared with 74% before its introduction. 67% report that they do not feel stressed to 50% previously. The interviews indicate that employees feel they can influence their working hours, reduced working hours and that they have more time for recovery. Less positive experiences were concerns about the salary when the employees have a significant impact on the salary by themselves. Many employees believe that patient safety is positively affected because employees are happier and more rested when they work, it minimizes the risks of adverse events. Patient safety is also affected by the skills have been strengthened because there are fewer agency staff on duty. Economic model resulted in a deficit of 1% of the personnel budget in 2011, but in 2012 we have a positive outcome of about 700 000 SEK during the first 4 months. Discussion The needs-based staffing model resulted in the employees experienced greater job satisfaction and increased recovery, and the clinic has had a more balanced staffing. Employees feel that patients are affected positively and when the employees are happier at work, partly because expertise has been strengthened because there are fewer substitutes. Economically, the model has proven to be cost-neutral, which was a requirement.
WALLNÉR, JOHAN, and CHRISTOFFER HOLM. "Network Coopetition – Samarbete mellankonkurrerande aktörer inom hälso- och sjukvården : En fallstudie av vårdkedjan för patienter ibehov av neurokirurgisk vård inom Stockholms län ochGotlands län." Thesis, KTH, Industriell Management, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-154484.
Full textThe overall purpose of this thesis was to investigate whether network coopetition, cooperation between competitive actors, can increase the value creation within the health care system. Within health care, network coopetition is a subject granted little attention in previous research. To fulfil the purpose a model for network coopetition within the health care system was developed. The model was the applied to one part of the chain of care for patients in need of neurosurgery. The results from this thesis show: (1) The conditions for network coopetition in the chain of care for patients in need of neurosurgery are fulfilled. (2) Examples of horizontal network coopetition have been found in the studied chain of care. (3) There is an existing discrepancy between how each actor recognizes its own and the other actors’ value creation. (4) The value creation ought to be evaluated as a common system where all actors are taken into account and at a process level where all stakeholders are considered. These results supports the final conclusion that network coopetition ought to be able to increase the value creation for highly specialized chain of cares with a large share of within-county patients.
Katisko, J. (Jani). "Intraoperative imaging guided delineation and localization of regions of surgical interest:feasibility study." Doctoral thesis, Oulun yliopisto, 2012. http://urn.fi/urn:isbn:9789514297519.
Full textTiivistelmä Tutkimus käsittelee magneettikuvauksen (MK), ultraäänikuvauksen (UÄ) ja tietokonetomografian (TT) käyttöä aivojen neurokirurgisissa operaatioissa. Päämääränä oli muodostaa edellä mainittuja menetelmiä soveltamalla leikkauksen aikaisen kuvantamisen konsepteja, joita voidaan käyttää aivotuumoreiden poistoissa ja aivojen stereotaktisissa toimenpiteissä. Työssä on myös tutkittu konseptien käytettävyyttä ja tarkkuutta. Leikkauksen aikaisen magneettikuvauksen tutkimiseksi suunniteltiin ja toteutettiin resistiiviseen ja avoimeen 0,23 T:n MK-laitteistoon perustuva leikkauksen aikaisen magneettikuvauksen konsepti. Horisontaalisesti avoin, resistiivinen ja matalakenttäinen MK-laitteisto mahdollisti neurokirurgisen potilaan kuvantamisen tarkoituksenmukaisella kuvanlaadulla ja kirurgisen toiminnan samassa tilassa vähäisellä potilaan siirtämisellä kuvantamis- ja operointialueen välillä. Magneettikentässä työskentelyyn liittyvät riskit voitiin minimoida sammutettavan magneettikentän avulla. Kasvainkudoksen ympärille muodostuva aivoturvotus voi hankaloittaa leikattavan alueen paikantamista. Rajapinnan korostamiseksi selvitettiin käänteispalautukseen perustuvan MK-sekvenssin mahdollisuuksia vaimentaa aivoturvotuksesta tulevaa signaalia matalakenttäisessä magneettikuvauksessa. Aivoturvotuksen suppressointi magneettikuvista todettiin lupaavaksi työkaluksi kirurgisesti poistettavan aivokasvainalueen rajaamisessa, mutta sen käytettävyys leikkauksen aikana osoittautui rajalliseksi. Leikkauksen aikainen ultraäänikuvaus liitettiin yhteen leikkauksen aikaisen magneettikuvauksen kanssa käyttämällä apuna neuronavigointilaitteistoa. Yhdistämällä nämä kaksi leikkauksen aikaista kuvantamismenetelmää saatiin täsmällisempää tietoa operoitavan kohteen sijainnista ja rajautumisesta. Stereotaktisen syväaivostimulaattorin asennuksen ohjaamiseksi ja kontrolloimiseksi kehitettiin menetelmä, jossa hyödynnetään kartiokeila-TT-laitteistoa leikkauksen aikana. Menetelmä mahdollisti potilaan kuvantamisen kaksi- ja kolmiulotteisesti leikkauksen aikana. Menetelmässä ratkaistiin käytetyn kuvantamislaitteen puutteellisen kuva-alan aiheuttamat rajoitukset. Tiedon avulla voitiin määrittää tarkasti kohdetumakkeiden stereotaktiset koordinaatit, kontrolloida toimenpiteen eri vaiheissa aivoissa käytettävien instrumenttien paikka ja varmentaa aivoihin jätettävien elektrodien lopullinen sijainti. Kuvantamisen avulla kyettiin poissulkemaan leikkauksen aikana mahdollinen aivoverenvuoto. Työn tulokset osoittavat, että leikkauksen aikainen kuvantaminen ja neuronavigointi tulisi olla käytettävissä neurokirurgisissa keskuksissa. Käytettävät menetelmät tulisi valikoida toimenpiteen mukaan ja menetelmiä soveltavien tulisi olla perehtyneitä eri modaliteettien ominaisuuksiin
Andersson, Julia, and Clara Helenius. "Effekter av neurokirurgi i vaket tillstånd på postoperativ tal- och språkförmåga." Thesis, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-273569.
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