Academic literature on the topic 'Neuroinflammatory cytokine expression'
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Journal articles on the topic "Neuroinflammatory cytokine expression"
Alasmari, Fawaz, Musaad A. Alshammari, Abdullah F. Alasmari, Wael A. Alanazi, and Khalid Alhazzani. "Neuroinflammatory Cytokines Induce Amyloid Beta Neurotoxicity through Modulating Amyloid Precursor Protein Levels/Metabolism." BioMed Research International 2018 (October 25, 2018): 1–8. http://dx.doi.org/10.1155/2018/3087475.
Full textGriffin, W. Sue T., and Steven W. Barger. "Neuroinflammatory Cytokines—The Common Thread in Alzheimer Pathogenesis." US Neurology 06, no. 02 (2010): 19. http://dx.doi.org/10.17925/usn.2010.06.02.19.
Full textGriffin, W. Sue T., and Steven W. Barger. "Neuroinflammatory Cytokines - The Common Thread in Alzheimer Pathogenesis." European Neurological Review 6, no. 2 (2011): 89. http://dx.doi.org/10.17925/enr.2011.06.02.89.
Full textWu, Ling-Hsuan, Chingju Lin, Hsiao-Yun Lin, Yu-Shu Liu, Caren Yu-Ju Wu, Cheng-Fang Tsai, Pei-Chun Chang, Wei-Lan Yeh, and Dah-Yuu Lu. "Naringenin Suppresses Neuroinflammatory Responses Through Inducing Suppressor of Cytokine Signaling 3 Expression." Molecular Neurobiology 53, no. 2 (January 13, 2015): 1080–91. http://dx.doi.org/10.1007/s12035-014-9042-9.
Full textCho, Jun Hwi, Dae Hyun Kim, Jong Suk Lee, Mi-Suk Seo, Mi Eun Kim, and Jun Sik Lee. "Sargassum horneri (Turner) C. Agardh Extract Regulates Neuroinflammation In Vitro and In Vivo." Current Issues in Molecular Biology 44, no. 11 (November 3, 2022): 5416–26. http://dx.doi.org/10.3390/cimb44110367.
Full textKelty, Taylor J., Xuansong Mao, Nathan R. Kerr, Thomas E. Childs, Gregory N. Ruegsegger, and Frank W. Booth. "Resistance-exercise training attenuates LPS-induced astrocyte remodeling and neuroinflammatory cytokine expression in female Wistar rats." Journal of Applied Physiology 132, no. 2 (February 1, 2022): 317–26. http://dx.doi.org/10.1152/japplphysiol.00571.2021.
Full textYuhas, Yael, Shai Ashkenazi, Eva Berent, and Abraham Weizman. "Clozapine Suppresses the Gene Expression and the Production of Cytokines and Up-Regulates Cyclooxygenase 2 mRNA in Human Astroglial Cells." Brain Sciences 12, no. 12 (December 12, 2022): 1703. http://dx.doi.org/10.3390/brainsci12121703.
Full textHan, Shu, Fan Zhang, Zhiying Hu, Yayi Sun, Jing Yang, Henry Davies, David T. W. Yew, and Marong Fang. "Dose-Dependent Anti-Inflammatory and Neuroprotective Effects of anανβ3 Integrin-Binding Peptide." Mediators of Inflammation 2013 (2013): 1–24. http://dx.doi.org/10.1155/2013/268486.
Full textMuscat, Stephanie M., and Ruth M. Barrientos. "The Perfect Cytokine Storm: How Peripheral Immune Challenges Impact Brain Plasticity & Memory Function in Aging." Brain Plasticity 7, no. 1 (August 23, 2021): 47–60. http://dx.doi.org/10.3233/bpl-210127.
Full textHenry, Christopher J., Yan Huang, Robert Dantzer, Rodney W. Johnson, and Jonathan P. Godbout. "Exaggerated sickness behavior and brain proinflammatory cytokine expression in aged mice in response to intracerebroventricular lipopolysaccharide (B13)." Journal of Immunology 178, no. 1_Supplement (April 1, 2007): LB3. http://dx.doi.org/10.4049/jimmunol.178.supp.b13.
Full textDissertations / Theses on the topic "Neuroinflammatory cytokine expression"
Sciara, Aubrey N., Brooke Beasley, Jessica D. Crawford, Emma P. Anderson, Tiffani Carrasco, Shimin Zheng, Gregory A. Ordway, and Michelle J. Chandley. "Neuroinflammatory Gene Expression Alterations in Anterior Cingulate Cortical White and Gray Matter of Males With Autism Spectrum Disorder." Digital Commons @ East Tennessee State University, 2020. https://dc.etsu.edu/etsu-works/8591.
Full textShen, Yi-Chun, and 沈怡君. "Fisetin inhibits neuroinflammatory responses and up-regulates anti-inflammatory cytokine expressions in microglia." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/05424927036476713300.
Full text中國醫藥大學
醫學檢驗生物技術學系碩士班
101
Microglia, is the resident innate immune cell in the central nervous system (CNS). Microglia has been implicated as active contributor to neuronal damage, and provides an initial line defence against invading pathogens. In actived form, microglia cause reactive oxygen species (ROS) production, and neuroinflammation result to cytotoxicity. Fisetin, one of the major flavonol that found in a wide variety of fruits and vegetables, has anti-oxidant and anti-inflammatory activity. However, the effects of fisetin on neuroinflammatory responses in microglia were still poorly understood. In this study, we investigated the signaling pathways involved in anti-inflammatory responses caused by fisetin in microglia. First, fisetin caused concentration-dependent inhibits ROS and nitric oxide (NO) production. In addition, fisetin also inhibits iNOS and interleukin-1β (IL-1β) mRNA in a concentration-dependent manner. Moreover, fisetin also up-regulates the anti-inflammatory cytokine production, such as heme oxygenase-1 (HO-1), forkhead box P3 (FOXP3) and suppressor of cytokine signaling-3 (SOCS-3). HO-1 activator CoPP IX dramatically reversed LPS/IFN-γ-induced iNOS/NO production. Furthermore, fisetin increased p38 and Akt phosphorylation time-dependently. On the other hand, fisetin can effectively inhibit the LPS/IFN-γ stimulated signal transducer and activator of transcription-1 (STAT-1) activation of time-dependently. In a mouse model, fisetin showed significant anti-neuroinflammatory effects on microglial activation and motor behavior deficits. Our results indicate that fisetin potentially inhibits ROS generation, reduces iNOS/NO production and regulates anti- neuroinflammatory cytokine expression in microglia. With a future understanding of these signal transduction pathways, microglia activation may could enhance maintain inflammatory homeostasis, and this offers new insights for developing therapeutic approaches to treat novel anti-inflammatory-related disorders.
Book chapters on the topic "Neuroinflammatory cytokine expression"
Qian, Xueshen, Shuang Zhang, Lian Duan, Fengchun Yang, Kun Zhang, Fuhua Yan, and Song Ge. "Periodontitis Deteriorates Cognitive Function and Impairs Neurons and Glia in a Mouse Model of Alzheimer’s Disease." In Advances in Alzheimer’s Disease. IOS Press, 2022. http://dx.doi.org/10.3233/aiad220042.
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