Books on the topic 'Neurodegenerative'

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1

Neurodegenerative diseases. Austin, Tex: Landes Bioscience, 2011.

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2

Dominguez, Celia, ed. Neurodegenerative Diseases. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-16758-4.

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3

Galimberti, Daniela, and Elio Scarpini, eds. Neurodegenerative Diseases. London: Springer London, 2014. http://dx.doi.org/10.1007/978-1-4471-6380-0.

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4

Hardiman, Orla, Colin P. Doherty, Marwa Elamin, and Peter Bede, eds. Neurodegenerative Disorders. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-23309-3.

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5

Hardiman, Orla, and Colin P. Doherty, eds. Neurodegenerative Disorders. London: Springer London, 2011. http://dx.doi.org/10.1007/978-1-84996-011-3.

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6

Galimberti, Daniela, and Elio Scarpini, eds. Neurodegenerative Diseases. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-72938-1.

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7

Ahmad, Shamim I., ed. Neurodegenerative Diseases. New York, NY: Springer US, 2012. http://dx.doi.org/10.1007/978-1-4614-0653-2.

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8

Beart, Philip, Michael Robinson, Marcus Rattray, and Nicholas J. Maragakis, eds. Neurodegenerative Diseases. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-57193-5.

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9

Fiskum, Gary, ed. Neurodegenerative Diseases. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4899-0209-2.

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10

Ahmad, Shamim I. Neurodegenerative Diseases. New York, NY: Springer US, 2012.

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11

B, Caine Donald, ed. Neurodegenerative diseases. Philadelphia: W.B. Saunders Co., 1994.

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12

Peplow, Philip V., Bridget Martinez, and Thomas A. Gennarelli, eds. Neurodegenerative Diseases Biomarkers. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-1712-0.

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13

Mattson, Mark P. Pathogenesis of Neurodegenerative Disorders. New Jersey: Humana Press, 2001. http://dx.doi.org/10.1385/159259106x.

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14

Verkhratsky, Alexei, Margaret S. Ho, Robert Zorec, and Vladimir Parpura, eds. Neuroglia in Neurodegenerative Diseases. Singapore: Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-13-9913-8.

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15

Rai, Mahendra, and Alka Yadav, eds. Nanobiotechnology in Neurodegenerative Diseases. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-30930-5.

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16

Mohamed, Essa, ed. Handbook of Neurodegenerative Disorders. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-3949-5.

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17

W, Langston J., and Young Anne B. 1947-, eds. Neurotoxins and neurodegenerative disease. New York, N.Y: New York Academy of Sciences, 1992.

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18

Saghir, Atif N. Free radicals in neurodegenerative disease. Birmingham: University of Birmingham, 1996.

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19

Metal ions and neurodegenerative disorders. Singapore: World Scientific, 2003.

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20

Astrid, Sigel, Sigel Helmut, and Sigel Roland K. O, eds. Neurodegenerative diseases and metal ions. Chichester, West Sussex, England: Wiley, 2006.

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21

P, Doherty Colin, and SpringerLink (Online service), eds. Neurodegenerative Disorders: A Clinical Guide. London: Springer-Verlag London Limited, 2011.

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22

C, Mobley William, Christen Yves, and SpringerLink (Online service), eds. Intracellular Traffic and Neurodegenerative Disorders. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009.

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23

Vega, Irving E., and Timothy J. Collier, eds. Unraveling Neuroprotective and Neurodegenerative Signals in Neurodegeneration. Frontiers Media SA, 2016. http://dx.doi.org/10.3389/978-2-88919-956-3.

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24

Neurodegenerative Diseases. Springer, 2010.

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25

Trojanowski, John Q., John Q. Trojanowski M. D, Christopher Clark M. D, and Christopher M. Clark. Neurodegenerative Dementias. McGraw-Hill Professional, 1999.

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26

Dominguez, Celia. Neurodegenerative Diseases. Springer, 2010.

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27

Neurodegenerative Disorders. Greenhaven Press, 2012.

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28

Engdahl, Sylvia. Neurodegenerative Disorders. Greenhaven Publishing LLC, 2013.

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29

Dominguez, Celia. Neurodegenerative Diseases. Springer, 2011.

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30

G, Jolles, Stutzmann J. M, and Rhône-Poulenc Round Table Conference (8th : 1993 : Annecy, France), eds. Neurodegenerative diseases. London: Academic Press, 1994.

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31

Neurodegenerative Disorders. HG group, 2018.

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32

Cummings, Jeffrey L., and Jagan A. Pillai, eds. Neurodegenerative Diseases. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190233563.001.0001.

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With an increasingly aging population, neurodegenerative diseases-such as Alzheimer’s disease, Lewy body dementia, frontotemporal dementia, and Parkinson’s disease-are becoming more prevalent in the world. This is an area of rapidly growing high-impact research as these neurodegenerative diseases are a huge burden for individuals, families, and societies both in quality of life and in healthcare costs. Finding novel therapeutic targets for neurodegenerative diseases is the premier medical challenge for this century. Classically each of these diseases has been viewed as a distinct entity with well-delineated clinical and pathological features. Recent research findings have revealed multiple commonalities across them; proteomic, genetic, cellular, and network mechanisms across neurodegenerative diseases. This conceptual revolution in our understanding of these neurodegenerative diseases as sharing unifying features is underpinned by underlying protein misfolding dysfunction and its consequences over time. As we search for new therapies and management of these neurodegenerative diseases, this book provides an effective source book of insights from experts that have played key roles in this conceptual revolution. Our goal is to enable better care of patients and to help build collaboration across research in multiple specializations that could help advance future insights and facilitate novel therapeutics.
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33

Cummings, Jeffrey L., and Jagan A. Pillai. Neurodegenerative Diseases. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190233563.003.0001.

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Neurodegenerative diseases (NDDs) are growing in frequency and represent a major threat to public health. Advances in scientific progress have made it clear that NDDs share many underlying processes, including shared intracellular mechanisms such as protein misfolding and aggregation, cell-to-cell prion-like spread, growth factor signaling abnormalities, RNA and DNA disturbances, glial cell changes, and neuronal loss. Transmitter deficits are shared across many types of disorders. Means of studying NDDs with human iPS cells and transgenic models are similar. The progression of NDDs through asymptomatic, prodromal, and manifest stages is shared across disorders. Clinical features of NDDs, including cognitive impairment, disease progression, age-related effects, terminal stages, neuropsychiatric manifestations, and functional disorders and disability, have many common elements. Clinical trials, biomarkers, brain imaging, and regulatory aspects of NDD can share information across NDDs. Disease-modifying and transmitter-based therapeutic interventions, clinical trials, and regulatory approaches to treatments for NDDs are also similar.
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34

Kishore, Uday, ed. Neurodegenerative Diseases. InTech, 2013. http://dx.doi.org/10.5772/45957.

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35

Domínguez, Celia. Neurodegenerative Diseases. Springer Berlin / Heidelberg, 2013.

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36

Ovádi, Judit, and Ferenc Orosz. Protein folding and misfolding : neurodegenerative diseases: Neurodegenerative diseases. Judit Ovadi, 2010.

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37

Zetterberg, Henrik, and Jonathan M. Schott. Fluid Biomarkers Indicative of Neurodegenerative Diseases. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190233563.003.0008.

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A major unifying feature of neurodegenerative diseases (NDDs) is excessive neuronal loss. Depending on when and where this occurs, patients may express distinct neurological and psychiatric symptoms. Neurodegeneration is accompanied by protein aggregation, inflammation, and microglial activation that may be drivers of the disease or in some circumstances may be protective reactions to the neurodegenerative process. A key development over the past decade has been our ability to leverage these accompanying central nervous system changes to develop clinically impactful biomarkers of specific NDDs. This has been crucial in helping us develop an understanding the time line of progression of these diseases, in their early diagnosis and to help target patients appropriately in therapeutic clinical trials, This chapter gives an overview of both established and novel fluid biomarkers for neurodegeneration, protein accumulation, inflammation, and microglial activation across different neurodegenerative diseases. Common as well as disease-specific biomarker changes in cerebrospinal fluid and blood are emphasized.
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38

Knott, Andrew B., and Ella Bossy-Wetzel. Mitochondrial Changes and Bioenergetics in Neurodegenerative Diseases. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190233563.003.0012.

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Mitochondria are dynamic organelles that are of critical importance for cellular survival and health. Because mitochondria play central roles in energy production and synaptic maintenance, neurons are believed to be particularly vulnerable to mitochondrial dysfunction. The discovery that genetic mutations in genes coding for mitochondrial proteins cause neurodegenerative conditions further hinted at the likelihood that mitochondrial dysfunction is a key pathway of neurodegeneration. Indeed, a wealth of research has identified mitochondrial dysfunction as an early and shared event of all common neurodegenerative diseases, both genetic and sporadic in origin. Specific types of mitochondrial dysfunction that have been observed in most neurodegenerative diseases include bioenergetic failure, increased oxidative stress, mitochondrial DNA mutations, defective calcium handling, impaired mitochondrial dynamics, defective mitophagy, and decreased mitochondrial biogenesis. The search for drugs that successfully target these pathways of mitochondrial dysfunction in neurodegeneration is ongoing.
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39

1952-, Marwah J., and Teitelbaum Herman, eds. Advances in neurodegenerative disorders. Scottsdale, Ariz: Prominent Press, 1998.

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40

Imaging of Neurodegenerative Disorders. Thieme Medical Publishers, Incorporated, 2015.

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41

Neurodegenerative Diseases: Unifying Principles. Oxford University Press, Incorporated, 2016.

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42

Imaging in Neurodegenerative Disorders. Oxford University Press, 2014.

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43

Verkhratsky, Alexei, Vladimir Parpura, Margaret S. Ho, and Robert Zorec. Neuroglia in Neurodegenerative Diseases. Springer Singapore Pte. Limited, 2020.

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44

AMERICAN, SCIENTIFIC. Fragile Brain: Neurodegenerative Diseases. Blackstone Publishing, 2021.

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45

Editors, Scientific American. Fragile Brain: Neurodegenerative Diseases. Rosen Publishing Group, 2022.

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46

Mattson, Mark P. Pathogenesis of Neurodegenerative Disorders. Humana Press, 2001.

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47

Books, Gregg. Prions and Neurodegenerative Disease. Independently Published, 2020.

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48

Prasad, Kedar N. Neurodegenerative Disease and Micronutrients. CRC Press, 2014. http://dx.doi.org/10.1201/b17497.

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49

McBurney, John W. Pesticides and Neurodegenerative Disorders. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190490911.003.0008.

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Neurodegenerative diseases, which are characterized by neuronal degeneration, include Alzheimer disease (AD), Parkinson disease (PD), and amyotrophic lateral sclerosis (ALS). Their worldwide prevalence is increasing as the global population ages. The causes reflect interactions between genetics and environmental factors such as increasing urbanization, industrialization, and widespread use of chemicals, including insecticides, fungicides, and herbicides. Epidemiologic data suggest that exposure to many of these pesticides increases the risk of neurodegeneration. The best-defined mechanism for this association is mitochondrial toxicity resulting in increased reactive oxygen species. In PD and AD, the associated accumulation of aggregates of insoluble, misfolded proteins results in the formation of Lewy bodies and neurofibrillary tangles, respectively. Pesticide exposures can be reduced by modifying food choices and applying integrated pest management in schools, businesses, and homes. Medical professionals can counsel patients about limiting exposure to pesticides and decreasing the risk of neurodegenerative disorders.
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50

Desikan, Rahul, Celeste Karch, and Leo P. Sugrue, eds. Genetics of Neurodegenerative Diseases. Frontiers Media SA, 2021. http://dx.doi.org/10.3389/978-2-88971-780-4.

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