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1
Manco, Martínez Miguel Ángel, Gasco Graciela Yasmine Troll, and Ramírez Suang Kelly Wong. "Medicina natural. Vida natural." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2019. http://hdl.handle.net/10757/626250.
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En nuestro país, el número de personas que padecen enfermedades crónicas aumenta cada año, los tratamientos farmacológicos disponibles en el mercado no están mostrando eficacia en los resultados contra estas enfermedades, además de generar una gran cantidad de efectos secundarios por su ingesta o suministración, lo que conlleva a plantear soluciones menos nocivas para la salud que mejoren la calidad de vida de estos pacientes. Asimismo, el apoyo de la familia y de los amigos es importante para acompañar en el duelo (aceptación de la enfermedad y cambios que producirá en la vida diaria) y es por esta razón que aquellos “cuidadores primarios” también requieren del acompañamiento adecuado para poder superar o sobrellevar estas situaciones adversas que afectan su calidad de vida.
La demanda en el consumo del aceite de cannabis está en auge dado a los grandes beneficios que ofrece en el tratamiento de enfermedades como el cáncer, la epilepsia y enfermedades degenerativas.
En la actualidad en el Perú, no se cuenta con boticas especializadas para la dispensación de aceite de cannabis que ofrezca una trazabilidad comprobada y en muchos casos se debe recurrir al mercado negro para acceder a este oleo.
La propuesta de productos naturales “Vida Natural” es ofrecer Aceite de Cannabis en diferentes concentraciones, 4%, 10% y 15%, con calidad y trazabilidad comprobada.
El proyecto requiere una inversión total de S/148,720. Nuestro equipo de trabajo asumirá la inversión del 60%, y requerimos el financiamiento de S/59,488 para poner en marcha la idea de negocio.In our country the number of people who suffer from chronic sicknesses increase each year. The available drug therapies on the market are not showing efficiency in the results against this sicknesses. Moreover, they produce a big quantity of side effects by its intake or supply, which means to develop less harmful solutions for the health that improves the life quality of patients. In the same way, the support of the family and friends is important to accompany in the in the mourning (the approval of the sickness and changes that will produce in the daily life) and that is why for some “primary caregivers” need the appropriate accompaniment to get to cope and overcome these adverse situations that affect their quality of life. The consumer demand for cannabis oil is on the rise given to the great benefits that have on the treatment of sicknesses such as cancer, epilepsy, and degenerative diseases. Nowadays in Peru, there are no specialized drugstores for the dispensation of cannabis oil that offer a proven traceability and in many cases the black market must be resorted to access this Oleo. The proposal for natural products called “Vida Natural” is to offer cannabis oil in different concentrations, 4%, 10%, and 15% with quality and traceability proven. Our project requires a total investment of S/148,720. Our work team will assume the investment of 60% and we require the funding for S/59,488 to start a business of our enterprising.
Trabajo de investigación
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Almeida, Maria Inês Pedro de. "Espaço natural de transição.Integração da componente natural em modelos de cidades compacta." Master's thesis, Faculdade de Arquitectura de Lisboa, 2011. http://hdl.handle.net/10400.5/3471.
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Tese de Mestrado em Arquitectura com a especialização em ArquitecturaO presente relatório final de projecto tem como objecto de estudo o Espaço Natural de Transição e de que forma é que a componente natural, integrada em modelos de cidades compactas, pode contribuir para um futuro desenvolvimento sustentável das cidades. O crescimento do meio urbano está intimamente relacionado com os processos de fixação de população nas cidades, induzidas por constantes mutações que a humanidade tem enfrentado ao longo dos tempos. No entanto, este crescimento urbano nem sempre tem sido feito segundo um trabalho de planeamento urbano cuidado, o que tem tido como consequência, o desenvolvimento de cidades cada vez mais descaracterizadas, descompactadas e diluídas no território, repletas de rupturas, obstáculos e vazios expectantes. Esta situação acarreta consigo diversos problemas de mobilidade, poluição atmosférica e consumos, tanto energéticos e de recursos, como também de tempo. Este projecto tem como pressuposto base, a tentativa de contrariar o fenómeno de “sprawl” urbano intensificado nas últimas décadas, assentando pelo contrário, na ideia de compactação, densificação e modernização urbana. Propõe-se então, a construção de modelos de cidades compactas que, por um lado privilegiem a aproximação de usos habitacionais, trabalho, educacionais, culturais e de lazer e que por outro, integrem a componente natural de forma generosa no tecido da cidade, sem que esta surja como um elemento de ruptura, mas sim como um Espaço Natural de Transição. Defende-se que este poderá ser um possível caminho para um futuro mais sustentável das cidades do amanhã, onde a população possa atingir, de forma plena, níveis de vida que correspondam às suas necessidades e aspirações.
This dissertation focuses on the Natural Transition Space and how the natural component, when integrated in models of compact cities, can contribute to a sustainable development of cities. The growth of urban areas is closely related to the processes of settlement of people in cities, induced by the constant changes that mankind has undergone throughout the ages. However, this urban growth has not always occurred according to a careful urban planning, which resulted in the development of cities increasingly deprived of their identity, uncompacted and diluted in the territory, full of breaches, obstacles and bleak wastelands. This situation brings with it several mobility issues, air pollution and consumption, not only of energy and resources, but also of time. The basic premise of this project is to inhibit the phenomenon of urban sprawl, which has been growing over the past decades, while defending the idea of urban compactness, densification and upgrading. This dissertation recommends the construction of models of compact cities that, not only favour the proximity of residential, working, educational, cultural and leisure areas, but also integrate the natural component into the structure of the city in such a way that it will not be considered a disruptive element but a Natural Transition Space. We support the idea that this could be a possible path to a more sustainable future of the cities of tomorrow, where the population will be able to fully achieve a standard of living that matches its needs and expectations.
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Walton, Sara, and n/a. "Contesting natures : a discourse analysis of natural resource conflicts." University of Otago. Department of Management, 2008. http://adt.otago.ac.nz./public/adt-NZDU20080404.142212.
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This research explores the discursive formations involved in two environmental conflicts during which organisations were not permitted to carry out their proposed extractive activities. The conflicts were based on the West Coast of the South Island in New Zealand. The first involved sustainable native logging and the second was over the siting and extension of a gold mine.
Extensive archival and media searches were carried out to generate data on the conflicts. Interviews were also conducted to investigate the community position in more depth. The discourse theory of Laclau and Mouffe (2001 [1985]) is drawn upon as a framework to make sense of the conflicts. This framework was particularly useful as it enabled a close and careful examination of the antagonisms and addressed some of the ideological and power concerns with stakeholder analysis. The analysis involved identifying nodal points, subjectivity, subject positions and floating signifiers, which enabled certain hegemonic constructions.
The two conflicts were considerably different. The hegemonic constructions were quite similar and the notion of �being green� emerged as an antagonism that was at the heart of the conflicts and a key to understanding why these business organisations were unsuccessful. That is, who or what is given meaning as �being green� negates and de-legitimates other activity that is not deemed to be green. In these conflicts business organisations extracting natural resources and subjects supporting these organisational activities could not be green - when being green was constituted in terms of the clean green discourse operating economically and socially within New Zealand (see Bell, 1996). Consequently, not being green was deemed to be outside of what we see as New Zealanders as being important and thus should not occur in this country.
This research has implications for business organisations in New Zealand dealing with greening issues, especially as external stakeholders can have considerable influence on organisational activities. Theoretically it argues for a discursive approach to organisational stakeholder analysis in order to address power and subjectivity and for the organisation and natural environment literature to recognise the possibility of multiple meanings of nature. In particular, this thesis contributes to current organisation studies literature by explicitly focusing on �nature� as a concept. It shows that the meaning attributed to nature is a political process which can have consequences for preventing or enabling significant business organisational activities.
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González, Guerrero Alvaro, Briones Antonio Morales, and Novoa Cristián Vergara. "Tienda de productos naturales y orgánicos : el rincón natural." Tesis, Universidad de Chile, 2006. http://repositorio.uchile.cl/handle/2250/135257.
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Tesis para optar al grado de Magíster en AdministraciónDesde un tiempo a esta parte, se ha observado un cambio en los hábitos alimenticios de la población, en particular en los países más desarrollados. Es así como, algunas investigaciones han constatado que los estadounidenses estarían mucho más sensibles y preocupados de conocer la composición de los alimentos que consumen, tendiendo a preferir alimentos con bajos niveles de sustancias químicas como son los productos naturales y orgánicos. En Chile en tanto, estudios muestran que existiría cierta preocupación de algunos consumidores al respecto, lo que estaría generando una incipiente demanda por este tipo de productos. Dentro del contexto antes señalado se enmarca el proyecto de negocio que a continuación se describe. La idea es implementar una tienda donde se comercialicen productos naturales y orgánicos, con el objetivo de cubrir una demanda parcialmente satisfecha por el mercado en la actualidad, cuestión que representa la oportunidad de apoderarse del sobre precio adicional que estarían dispuestos a pagar los consumidores por las bondades que estos productos poseen, entre las que destacan ser inocuos para el organismo, ser más sabrosos y, por sobre todo, poseer mayor poder nutritivo El modelo de negocio propuesto se basa en la producción y comercialización de productos naturales y orgánicos a través de una tienda, cuidadosamente ornamentada con un estilo rústico y acogedor. Cabe consignar que los objetivos del negocio serán: lograr sinergias con los proveedores a través de encadenamientos productivos; asegurar parte del mix de la tienda mediante la integración vertical hacia atrás en la cadena de suministro, establecer un mix altamente diversificado y estandarizado, posicionar una marca propia para contribuir a la diferenciación y desarrollar una tienda virtual potenciando la venta de los productos a través de Internet. El negocio propuesto tendrá como mercado objetivo los consumidores de los estratos socioeconómicos ABC1 y C2 de Santiago. Esto, en base a que serían estos consumidores quienes conocerían mejor las bondades de estos productos, lo que sumado al mayor estatus reportado por la asociación con estilos de vida más sanos, aumentarían las preferencias de este segmento. Adicionalmente, la investigación de mercado realizada permitió determinar que existe disponibilidad a pagar un sobre precio por estos productos, llegando incluso a valores por sobre el 100%. Los potenciales clientes, fueron segmentados en base a criterios de comportamiento, determinándose cuatro sub-segmentos: vegetarianos, amantes de la comida sana, consumidores de moda y profesionales de la gastronomía. Del análisis de las características de la industria, se concluyó que la estrategia apropiada sería la de nicho, puesto que se apunta a crear valor a un grupo específico de compradores. La estrategia se funda en la construcción de marca, un fuerte posicionamiento de los beneficios derivados de su consumo, una fuerte fidelización de clientes y una administración creativa. El plan de marketing contempla que la tienda entregue dos tipos de productos: los naturales y orgánicos propiamente tal y un servicio de excelencia, en cuanto a información nutricional y formas de cómo consumirlos. La promoción se realizará a través de siete medios distintos con un costo de MM$ 7 para el primer año, incrementándose hasta MM$ 19,5 en el quinto. El precio será utilizado para dar una señal de calidad y, en promedio, tendrá un margen 50% superior respecto de productos sustitutos equivalentes. Se ha definido una “canasta tipo” que será comercializada por la tienda, la que tendrá un valor de $4.000. Los ingresos durante el primer año se espera asciendan MM$ 37,8 que corresponden a 9.453 ventas de la canasta tipo, mientras que para el quinto año las ventas llegarían a MM$ 202,8 equivalentes a 50.718 canastas. La evaluación financiera del proyecto asumió un horizonte de 5 años, arrojando un VAN de MM$ 65,3 a una tasa de descuento de 20,9%, con una inversión de MM$ 11,5. El punto de equilibrio se alcanzaría en el mes 19 de operación, el período de recuperación de la inversión sería de 3 años y la TIR, sin valor residual, sería de 54,7% y 69,8% incluyendo un valor residual calculado como 1,5 veces el EBITDA del quinto año. Los principales riesgos del negocio se centran en posibles quiebres de stock, caídas tanto en las proyecciones de demanda como en el precio de venta de los productos y, adicionalmente, en el ingreso de grandes actores al negocio. Para mitigar lo anterior, se contempló integrarse verticalmente hacia atrás en la cadena de valor, se realizaron estimaciones conservadoras de la demanda y precio de venta de los productos y, por último, se sensibilizaron estas variables para analizar su efecto y focalizar los esfuerzos en la estrategia planteada. Se considera la incorporación de un inversionista externo, que aportará el 25% de la inversión requerida y del capital de trabajo inicial. El resto, será financiado en partes iguales por los integrantes del equipo ejecutivo. Se constituirá una sociedad anónima cerrada de acuerdo a la legislación vigente.
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Novoa, Goicochea Zaniel I. "Valoración económica del patrimonio natural: las áreas naturales protegidas." Pontificia Universidad Católica del Perú. Centro de Investigación en Geografía Aplicada, 2012. http://repositorio.pucp.edu.pe/index/handle/123456789/119457.
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Economic Valuation of the natural patrimony: Protected Natural AreasThis paper offers some knowledge about the utility of Economic Valuation of Assets out of market methods, to allow management in general and as a guide to the planning of natural areas with valuable ecologic and landscaping aspects. Here, I show the importance of the Protected Natural Areas (ANP) in the national economy and their economic value. I describe the most used techniques in the valuation of ANPs with special attention to the direct using values through the application of cost of travel and contingent valuation methods.As an example of the use of these techniques, I present the application results at the Private Conservation Area-El Cañoncillo Natural Forest, with the objective to analyze the pertinence of the economic valuation by the adoption of conservation practices.El presente artículo brinda conocimientos sobre la utilidad de los métodos de valoración económica de los bienes sin mercado, tanto para su gestión en general como para que sirva de guía para la planificación de áreas naturales ecológica y paisajísticamente valiosas en particular. Muestra la importancia de las áreas naturales protegidas (ANP) en la economía nacional y su valoración económica. Se describen las técnicas más usadas en la valoración de las ANP, con especial atención en los valores de uso directo a través de la aplicación de métodos de costo de viaje y de valoración contingente (CVVC).Como ejemplo de uso y potencial de estas técnicas se presentan los resultados de su aplicación en el Área de Conservación Privada Bosque Natural El Cañoncillo, con el objetivo de analizar la viabilidad de la valoración económica por medio de la adopción de prácticas de conservación.
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Delashob, Hemen, and Björn Elmström. "Liquified Natural Gas Marine Fuel : Naturally Occuring Radioactive Material." Thesis, Linnéuniversitetet, Sjöfartshögskolan (SJÖ), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-84206.
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There seems to be enough information available on how different types of radiation may affect human health. There also seems to be adequate research made about NORM and how to handle this phenomenon. The image put forth by this study shows that the appearance of NORM within affected industries do not appear surprising or difficult to deal with. On the contrary it seems to be a well-known issue and safety measures have been adapted accordingly. It appears as if these issues have been overlooked regarding the systems where LNG is being used as a marine fuel. There is not enough data to conclude whether NORM is an issue or not in such systems.
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Swanson, Karrie. "Natural synthesis /." Online version of thesis, 2010. http://hdl.handle.net/1850/11987.
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Smith, M. V. "Natural cosmopolitics." Thesis, University of Reading, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.553688.
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Natural Cosmopolitics presents a spacepower theory that is designed to help policy makers and strategists understand what spacepower is and how states can use it to their benefit. What is offered is a holistic treatment of spacepower that includes the security, civil, and commercial space sectors. It shows how states can employ spacepower as another element of national power in the pursuit of security, prestige, and wealth. Unlike other attempts to produce a spacepower theory that draw on analogies to airpower, seapower, or groundpower, natural cosmopolitics traces its roots from the Big Bang forward. Discussions include the evolution of the Universe, space itself, the solar system, life on Earth, the current state system, and contemporary geopolitics within international relations. Spacepower is presented as a natural outcome of these evolutionary forces, strategically the same as the practice of power in the other operating environments, because the same political processes with the same motivations drive it. It is shown that the advent of spacepower has ushered in a revolution in strategic perspective. The global perspective of the Columbian Epoch is fading away as humanity comes to appreciate the Earth as a tiny little planet in a modest solar system in a Universe that may be filled with more galaxies than people. From this, general and specific principles of natural cosmopolitics are presented along with an analytical tool to help strategists anticipate how other states may respond with spacepower to various stimuli. The role of spacepower in both war and peace is also discussed. Finally, the threat of catastrophic asteroid impacts is analysed and the hypothesis is tested that states will cooperate to provide a planetary defence.
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Pantoja, Plaza Katherine Milagros, Quiroz Nelitza Lesly Bartolo, Livias Jenny Claudia, and Chinguel Eliana Marisol Guerrero. "Natural Organic." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2019. http://hdl.handle.net/10757/625357.
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En el presente trabajo desarrollaremos un modelo de negocio que surge debido a la necesidad que tienen hoy en día las mujeres de adquirir productos en diferentes cantidades y tamaños que le permitan disfrutar de una variedad de aromas y beneficios para su piel; debido a esto, nosotros ofreceremos productos al peso con la finalidad de que cada cliente pueda adquirir diferentes tamaños y cantidades según su necesidad. A la vez, estos productos artesanales serán elaborados con insumos naturales que certifiquen su calidad, y podrán ser encontrados en los establecimientos más concurridos de Lima.
En la primera parte del presente trabajo se analizará los aspectos generales del negocio y su planeamiento estratégico en donde se realizará el análisis interno y externo; a la vez crearemos nuestra visión y misión que nos permitirá llegar a nuestro público objetivo. Además, se desarrollará las estrategias y objetivos, los cuales determinarán los pasos a seguir para el buen funcionamiento de la empresa.
Para conocer la viabilidad del producto y el modelo de negocio se realizó una investigación de mercado, que permitió conocer las características de nuestro público objetivo; a la vez, conocer la oferta y demanda, para identificar la cantidad de personas que están interesadas en el producto y tipo de negocio.
En el aspecto financiero detallaremos la inversión total a necesitar para la implementación del negocio, además analizaremos los estados financieros, flujo de caja e indicadores de rentabilidad, que nos permitirán conocer la rentabilidad que obtendrá el negocio. Finalmente, se realizará un análisis de riesgo y punto de equilibrio; con una proyección de cinco años.In the present work we will develop a business model that arises because of the need of women today to purchase products in different quantities and sizes that allow you to enjoy a variety of aromas and benefits for their skin because of this we will offer products to the weight with the purpose of that each client may purchase different sizes and quantities according to your needs. At the same time, these artisanal products will be developed with natural inputs that certify their quality and may be found in the most crowded places of Lima. In the first part of this paper we will analyze the general aspects of the business and its strategic planning in where the internal and external analysis, at the same time we will create our vision and mission that will allow us to reach our target audience. In addition, develop the strategies and objectives which will determine the steps to follow for the proper functioning of the company. To learn about the viability of the product and the business model is conducted a market research which allowed to know the characteristics of our target audience; at the same time, know the supply and demand, to identify the number of people who are interested in the product and type of business. In the financial aspect we will detail the total investment needed for the implementation of the business, in addition we will analyze the financial statements, cash flow and profitability indicators, which will allow us to know the profitability you will obtain the business. Finally, will be a risk analysis and point equilibrium; with a projection for five years.
Trabajo de investigación
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Diez, Canseco Soto Fernando Alonso, Delgado Silvio Enrique Carbajal, Gómez Noemí Maquera, Cardenas Renata Del Rocio Ramos, and Coral Javier Andres Chávez. "Natural club." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2020. http://hdl.handle.net/10757/654687.
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El presente proyecto de investigación tiene como finalidad la implementación de un negocio enfocado en la unificación de la oferta y la demanda de productos saludables selectos por medio de una plataforma online (marketplace), que busca promover y motivar al público a que adopte estilos de vida saludables. Este trabajo de investigación fue realizado en Lima Metropolitana a los NSE “A” Y “B”; teniendo un principal enfoque en quienes tienen perfiles digitales y buscan dinamismo en sus compras. Este modelo de negocio es atractivo, ya que vemos un consumidor interesado en mejorar su alimentación y tener un estilo de vida saludable, pero que no encuentra un lugar que le brinde una oferta unificada de todo lo que busca. Aprovechando que en el mercado existen pocas opciones que vuelvan dinámica la interacción entre ofertantes y demandantes, creamos Natural Club. Es un emprendimiento que permite a los vendedores ofertar sus productos, selectos y de alta calidad, de una manera rápida y sencilla, así como para el consumidor adquirirlos de la misma manera. Encargándose, además, de todos los envíos a domicilio y asegurándose de que cumplan con los altos estándares de salubridad que requiere la coyuntura COVID-19.
Para el desarrollo de este proyecto se efectuó un análisis exhaustivo que cubrió lo siguiente: Validación del Modelo de Negocio, Análisis Interno y Externo y Desarrollo de Plan Estratégico. Todo lo realizado se hizo con el objetivo de validar la viabilidad y sostenibilidad del presente proyecto.The purpose of this entrepreneurial project is to implement a business focused on unifying the supply and demand of select healthy products through an online platform (marketplace), which seeks to promote and motivate our consumers to adopt a healthier lifestyle. This project was carried out in Metropolitan Lima at SES (Socioeconomic status) "A" and “B”. We adopted a main focus on consumers with digital profiles that seek for dynamism in their purchases. This business model is attractive, since we see there are consumers willing to improve their diet and adopt a healthier lifestyle, but they do not find a place that provides a unified offer of everything they are looking for. Taking advantage that there are few options in the market where the interaction between suppliers and demanders is dynamic, we created Natural Club. This entrepreneurial project allows sellers to offer their selected and high quality products, quickly and easily, just as it is for our consumers to acquire them. All this while taking care of the delivery process, with all the sanitation and hygiene measures, due to Covid-19. For the development of this project, we carry out an exhaustive analysis that covered the following: Validation of the Business Model, Internal and External Analysis and the Development of the Strategic Plan. All the analysis was done with the aim of validating the viability and sustainability of this project.
Trabajo de investigación
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Diez, Canseco Soto Fernando Alonso, Delgado Silvio Enrique Carbajal, Gómez Noemí Maquera, Cardenas Renata Ramos, and Coral Javier Chavez. "Natural club." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2002. http://hdl.handle.net/10757/654687.
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El presente proyecto de investigación tiene como finalidad la implementación de un negocio enfocado en la unificación de la oferta y la demanda de productos saludables selectos por medio de una plataforma online (marketplace), que busca promover y motivar al público a que adopte estilos de vida saludables. Este trabajo de investigación fue realizado en Lima Metropolitana a los NSE “A” Y “B”; teniendo un principal enfoque en quienes tienen perfiles digitales y buscan dinamismo en sus compras. Este modelo de negocio es atractivo, ya que vemos un consumidor interesado en mejorar su alimentación y tener un estilo de vida saludable, pero que no encuentra un lugar que le brinde una oferta unificada de todo lo que busca. Aprovechando que en el mercado existen pocas opciones que vuelvan dinámica la interacción entre ofertantes y demandantes, creamos Natural Club. Es un emprendimiento que permite a los vendedores ofertar sus productos, selectos y de alta calidad, de una manera rápida y sencilla, así como para el consumidor adquirirlos de la misma manera. Encargándose, además, de todos los envíos a domicilio y asegurándose de que cumplan con los altos estándares de salubridad que requiere la coyuntura COVID-19.
Para el desarrollo de este proyecto se efectuó un análisis exhaustivo que cubrió lo siguiente: Validación del Modelo de Negocio, Análisis Interno y Externo y Desarrollo de Plan Estratégico. Todo lo realizado se hizo con el objetivo de validar la viabilidad y sostenibilidad del presente proyecto.The purpose of this entrepreneurial project is to implement a business focused on unifying the supply and demand of select healthy products through an online platform (marketplace), which seeks to promote and motivate our consumers to adopt a healthier lifestyle. This project was carried out in Metropolitan Lima at SES (Socioeconomic status) "A" and “B”. We adopted a main focus on consumers with digital profiles that seek for dynamism in their purchases. This business model is attractive, since we see there are consumers willing to improve their diet and adopt a healthier lifestyle, but they do not find a place that provides a unified offer of everything they are looking for. Taking advantage that there are few options in the market where the interaction between suppliers and demanders is dynamic, we created Natural Club. This entrepreneurial project allows sellers to offer their selected and high quality products, quickly and easily, just as it is for our consumers to acquire them. All this while taking care of the delivery process, with all the sanitation and hygiene measures, due to Covid-19. For the development of this project, we carry out an exhaustive analysis that covered the following: Validation of the Business Model, Internal and External Analysis and the Development of the Strategic Plan. All the analysis was done with the aim of validating the viability and sustainability of this project.
Trabajo de investigación
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Davidson, Clayton Simmons. ""Natural Disasters"." Thesis, University of North Texas, 2019. https://digital.library.unt.edu/ark:/67531/metadc1538761/.
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"Natural Disasters" is a cycle of five extractable movements for septet, conductor and computer. Each movement in the cycle is inspired by the ways that humans are affected by and respond to five different classes or categories of natural disasters: meteorological, such as hurricanes, tornados, and haboobs; geological, like earthquakes and landslides; hydrological, including flooding and sea level rise; wildfires; and extra-planetary disasters such as meteors and solar flares. The disaster types are used as overarching themes and also as sources for the organization of the movements and their surface details. This paper presents an overview of the conception and organization of cycle, the themes addressed in each movement and the compositional techniques used. The history of composers using weather or disaster-related themes in prior music is reviewed, and a survey of contemporary disaster-related compositions is presented.
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Clark, Laura L. "Natural crutch." Thesis, Virginia Polytechnic Institute and State University, 1993. http://hdl.handle.net/10919/52127.
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The proposed “natural crutch” provides ambulation assistance without the problems associated with arm-supported crutches. The new crutch has an exoskeleton structure which surrounds the disabled leg and carries the user's body weight while walking and standing. The load is transferred from the exoskeleton to the trunk of the body through a harness which lifts the pelvis on the impaired side. The intention is to simulate the internal skeleton’s natural load distribution while compensating for the impairment.
The crutch design is presented as a unique concept with an outlined proposal for a marketable prototype. Results of a full scale simulator test are used to determine areas requiring further development. All aspects of design attempt to include both engineering and industrial design perspectives.Master of Science
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Diez, Canseco Soto Fernando Alonso, Delgado Silvio Enrique Carbajal, Gómez Noemí Maquera, Coral Javier Chavez, and Cardenas Renata Del Rocio Ramos. "Natural club." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2020. http://hdl.handle.net/10757/654687.
Full textAbstract:
El presente proyecto de investigación tiene como finalidad la implementación de un negocio enfocado en la unificación de la oferta y la demanda de productos saludables selectos por medio de una plataforma online (marketplace), que busca promover y motivar al público a que adopte estilos de vida saludables. Este trabajo de investigación fue realizado en Lima Metropolitana a los NSE “A” Y “B”; teniendo un principal enfoque en quienes tienen perfiles digitales y buscan dinamismo en sus compras. Este modelo de negocio es atractivo, ya que vemos un consumidor interesado en mejorar su alimentación y tener un estilo de vida saludable, pero que no encuentra un lugar que le brinde una oferta unificada de todo lo que busca. Aprovechando que en el mercado existen pocas opciones que vuelvan dinámica la interacción entre ofertantes y demandantes, creamos Natural Club. Es un emprendimiento que permite a los vendedores ofertar sus productos, selectos y de alta calidad, de una manera rápida y sencilla, así como para el consumidor adquirirlos de la misma manera. Encargándose, además, de todos los envíos a domicilio y asegurándose de que cumplan con los altos estándares de salubridad que requiere la coyuntura COVID-19.
Para el desarrollo de este proyecto se efectuó un análisis exhaustivo que cubrió lo siguiente: Validación del Modelo de Negocio, Análisis Interno y Externo y Desarrollo de Plan Estratégico. Todo lo realizado se hizo con el objetivo de validar la viabilidad y sostenibilidad del presente proyecto.The purpose of this entrepreneurial project is to implement a business focused on unifying the supply and demand of select healthy products through an online platform (marketplace), which seeks to promote and motivate our consumers to adopt a healthier lifestyle. This project was carried out in Metropolitan Lima at SES (Socioeconomic status) "A" and “B”. We adopted a main focus on consumers with digital profiles that seek for dynamism in their purchases. This business model is attractive, since we see there are consumers willing to improve their diet and adopt a healthier lifestyle, but they do not find a place that provides a unified offer of everything they are looking for. Taking advantage that there are few options in the market where the interaction between suppliers and demanders is dynamic, we created Natural Club. This entrepreneurial project allows sellers to offer their selected and high quality products, quickly and easily, just as it is for our consumers to acquire them. All this while taking care of the delivery process, with all the sanitation and hygiene measures, due to Covid-19. For the development of this project, we carry out an exhaustive analysis that covered the following: Validation of the Business Model, Internal and External Analysis and the Development of the Strategic Plan. All the analysis was done with the aim of validating the viability and sustainability of this project.
Trabajo de investigación
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Armstrong, Holly. "Natural Flow." VCU Scholars Compass, 2006. http://scholarscompass.vcu.edu/etd/694.
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Nature never ceases to amaze me with momentary observations of fluid energy: the purposeful curvature of a blue heron's neck; the pattern of water as it sweeps across a rock sculpted by that very motion; the changing light and shadows created as wind blows through tall grasses. The spark of beauty in these moments lies in the energy that causes this constant change. To capture this energy, either potential or kinetic, and embody it through textures and flow of mass, is my essential goal as an artist.
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Vick, Jeffrey A. "Natural Selection." VCU Scholars Compass, 2006. http://scholarscompass.vcu.edu/etd/1254.
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My thesis work is about imagination. I use the collaborative efforts of the viewer's mind and my sculptures, or specimens, to make associations of real life animals. I feel this engages the viewer and in turn invites them to inspect the work on closer level. This is my ultimate goal in the work, to take hold of the viewer's curiosity and have them examine the work on a closer level.
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Siler, Chrischele M. "Natural courses." Morgantown, W. Va. : [West Virginia University Libraries], 2000. http://etd.wvu.edu/templates/showETD.cfm?recnum=1408.
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Baker, Adam William John. "Natural Habitat." Thesis, Baker, Adam William John (2007) Natural Habitat. PhD thesis, Murdoch University, 2007. https://researchrepository.murdoch.edu.au/id/eprint/2949/.
Full textAbstract:
The research herein relates to the development and ideology behind the creative piece Natural Habitat, and is concerned with exploring effective narrative techniques. The goal of this research is to provide a methodology towards creating effective narrative in the medium of hypertext by developing a better understanding of how narrative functions.
The research explores the social and cognitive elements of narrative, and the manner in which structure impacts the understanding and development of narrative. The genre boundaries of medium and content are explored to gain an understanding of reader preference and expectation. The concept of reader expectation is then applied to multiform narrative in order to understand its functionality, before the question of effective combination of these elements is raised in regards to the medium of hypertext. This methodology is then implemented in the piece Natural Habitat, testing the merit of this approach in the resulting work of fiction.
Natural Habitat is a story describing the journey four friends make through the Amazon jungle after surviving a plane crash. Isolated and in a hostile environment, the four survivors find themselves slipping into surreal worlds that seem futuristic, fantastic, horrific, and tinged with noir. Some begin to question their sanity, while others adapt to their environs readily, but each faces their darker side as the fears in their minds begin to play out on the landscape around them. Fighting to survive, their only chance is to find each other and to conquer their inner demons.
The story is both the exploration and implementation of the arguments of the thesis, with the research guiding the construction of the story from planning, through initial writings and up to the final presentation. Natural Habitat itself is presented as a traditional novel and a piece of hypertext, facilitating comparative analysis between the two mediums.
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Angulo, Geng José Luis, Cotrina Eric Jesús Quiroz, García David Anthony Pazos, and Mateo Alberto Aldo Valverde. "Natural Cake." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2018. http://hdl.handle.net/10757/625996.
Full textAbstract:
El presente trabajo tiene como finalidad desarrollar la viabilidad en la creación de un producto natural hecho con insumos orgánicos oriundos del Perú, aprovechando la tendencia de alimentarse saludablemente, con la intención de llevar un estilo de vida saludable, ya sea por mantener una buena salud, hábito de consumo o simplemente por el hecho de querer verse bien.
Natural Cake es un muffin hecho a base de ingredientes naturales nativos del Perú como la harina de tarwi que contiene un valor nutricional excepcional, pues presenta un alto porcentaje de proteínas, vitaminas y minerales; también está hecho con harina de quinua, rica en fibra y proteínas; cacao, rico en antioxidantes y vitaminas; todo esto endulzado con miel de caña, gran proporcionador de energía. Estos insumos, de calidad, son comercializados por comunidades campesinas del Perú quienes serán nuestros principales proveedores. El propósito es desarrollar y contribuir con el progreso de estas comunidades y servir como ejemplo de responsabilidad social.
Nuestro producto es una alternativa ideal para aquellas personas que no solo quieran una cultura light, también buscan consumir productos naturales y beneficiosos para su salud. Nuestro público objetivo son personas de edades entre 18 y 45 años del NSE A y B que gracias a nuestra investigación de mercado pudimos observar sus características y necesidades. En conclusión, Natural Cake busca, en nuestros consumidores, no solo ofrecer un producto delicioso, sino contribuir a conservar la buena salud y mejorar la calidad de vida de las personas.This study aims to develop the feasibility in the creation of a natural product made from organic inputs of Peru, taking advantage of the tendency to eat healthy, with the intention of putting a style of healthy lifestyle, either by maintaining a good health, habit of consumption or simply by the fact of wanting to look good. Natural Cake is a muffin made of native natural ingredients of Peru like flour tarwi containing exceptional nutritional value, because it has a high percentage of protein, vitamins and minerals; It is also made with quinoa, riched in fiber and protein meal; cocoa, rich in antioxidants and vitamins; all of this was sweetened with honey, great energy proportioner. Of quality, these inputs are marketed by the Peru communities who will be our main suppliers. The purpose is to develop and contribute to the progress of these communities, and serve as an example of social responsibility. Our product is an alternative for those who not only want a light culture, also seek to consume natural and beneficial for your health products. Our target audience are people aged between 18 and 45 of the NSE A and B which, thanks to our market research we could observe their characteristics and needs. In conclusion, Natural Cake search, our consumers, not only offer a delicious product, but contribute to maintaining good health and improve the quality of people's lives.
Trabajo de investigación
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Martínez, Fernández Francisca. "Fuerza natural." Tesis, Universidad de Chile, 2017. http://repositorio.uchile.cl/handle/2250/159477.
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Magíster en artes, mención artes visualesFuerza Natural es el título de esta tesis que se compone de tres capítulos: Guijarros, Paisaje y Naturaleza, recorriendo el escrito desde la especificidad de una piedra de río (que se reconoce como la estructura mínima del paisaje), pasando por el concepto de paisaje (que es manifestación de la intervención del hombre en la naturaleza, al seleccionar, limitar y encuadrar) para culminar con el sentido prístino que tiene la naturaleza atendiendo a su noción visible e invisible. Esta investigación está centrada en representaciones pictóricas que brotan y se desprenden de un “llamado de naturaleza”, guardando estrecha relación con desembrollar misterios y afectarse por estados contemplativos que finalmente se materializan en obras. Surgen así poéticas, análisis y búsquedas existenciales, conceptuales y materiales, transformadas en visualidad, en las que la responsabilidad del color y la forma son acompañadas por la intención e intuición de la pintura.
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Woolford, Thomas. "Natural theology and natural philosophy in the late Renaissance." Thesis, University of Cambridge, 2012. https://www.repository.cam.ac.uk/handle/1810/242394.
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Scholars have become increasingly aware of the need to understand the religious context of early modern natural philosophy. Despite some great strides in relating certain areas of Christian doctrine to the study of the natural world, the category ‘natural theology’ has often been subject to anachronism and misunderstanding. The term itself is difficult to define; it is most fruitful to think of natural theology as the answer to the question, ‘what can be known about God and religion from the contemplation of the natural world?’ There have been several erroneous assumptions about natural theology – in particular that it only consisted of rational proofs for the existence of God, that it was ecumenical in outlook, and that it was defined as strictly separate from Scriptural revelation. These assumptions are shown to be uncharacteristic of the late-sixteenth and early-seventeenth century. The study of natural theology needs to be better integrated into three contexts – the doctrinal, confessional, and chronological. Doctrinally, natural theology does not stand alone but needs to be understood within the context of the theology of revelation, justification, and the effects of the Fall. These doctrines make such a material difference that scholars always ought to delineate clearly between the threefold state of man (original innocence, state of sin, state of grace) when approaching the topic of ‘natural’ knowledge of God. Confessionally, scholars need to recognise that the doctrine of natural theology received different treatments on either side of the sectarian divide. In Catholicism, for instance, there were considerable spiritual benefits of natural theology for the non-Christian, while in Protestantism its benefits were restricted to those saved Christians who possessed Scriptural insight. Chronologically, natural theology does not remain uniform throughout the history of Christian theology but, being subject to changes occasioned by philosophical and theological faddism and development, needs to be considered within a particular locus. Research here focuses on late sixteenth-century orthodoxy as defined in confessional and catechismal literature (which has been generally understudied), and demonstrates its application in a number of case-studies. This thesis begins the work of putting natural theology into these three contexts. An improved understanding of natural theology, with more rigorous and accurate terminology and better nuanced appreciation of confessional differences, makes for a better framework in which to consider the theological context of early modern natural philosophy.
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Oldfield, Nigel Leigh. "Thiazole-containing natural and non-natural metal-complexing agents." Thesis, University of Nottingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.311763.
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Sequeira, André Assunção. "Ventilação natural (estudo de um caso de ventilação natural)." Master's thesis, Faculdade de Ciências e Tecnologia, 2010. http://hdl.handle.net/10362/4116.
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Dissertação apresentada à Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa para obtenção do grau de Mestre em Engenharia MecânicaO presente estudo teve como objectivo analisar a ventilação natural, recorrendo à simulação numérica. Aborda-se o problema da ventilação natural de um edifício em comunicação com o exterior através de duas aberturas de ventilação. Isto é, para a representação numérica do escoamento tridimensional assumiu-se um edifício de forma cúbica 5x5x5 m, em comunicação com o exterior através de duas aberturas de ventilação. Apesar dos escoamentos no interior dos edifícios serem promovidos pela acção conjunta do vento natural e da libertação de calor, para o referido estudo o escoamento só será promovido pela acção do vento natural. Por fim, com os resultados das várias simulações, teve-se como objectivo caracterizar as perdas de carga nas aberturas de ventilação, e nomeadamente, a influência da porosidade na perda de carga.
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Costello, Graham John. "Natural Law and Natural Rights in Nineteenth Century Britain." Thesis, The University of Sydney, 2013. http://hdl.handle.net/2123/10168.
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This thesis challenges the view of many historians that the natural law and natural rights tradition, while flourishing in the Enlightenment period, disappeared in nineteenth-century Britain with the expansion of the role of positive law, only to reappear post-World War II in human rights discourse. The focus of historians of political thought on canonical figures, Jeremy Bentham, John Austin, and John Stuart Mill, all of whom were antagonistic to the natural law and rights tradition has led them to fail to appreciate not only the continued role of natural law and rights but its development of a post-Enlightenment accommodation with positive law, resulting in a more pragmatic understanding of natural law. The examination of non-canonical figures who were nevertheless important in their time reveals the continued role of natural law as positive law expanded. The thesis is developed through the analysis of figures in areas where natural law was significant: Jurisprudence; the Law of Nations or International Law; and Spiritual Life. Jurisprudence was the area in which theorists of natural law mounted direct opposition to the theories of Jeremy Bentham, John Austin, and John Stuart Mill. The writers investigated include Charles Foster, an early nineteenth century proponent of natural law through his writings and lectures; the Scotsman, James Lorimer, writer and lecturer on jurisprudence and law of nations; and the Irish Catholic lawyer Denis Caufeild Heron. In International Law the advocates of natural law theory were Robert Phillimore, judge of the High Court of Admiralty; Travers Twiss and George Bowyer as civil lawyers; and James Lorimer. Writers on Natural Law in Spiritual Life, included Henry Drummond, lecturer and ecclesiast; George Combe, phrenologist; and John Seeley, historian; who were in conflict with churchmen over the church’s exclusive right to interpret religious teaching and the appropriate relationship between natural law and religion.
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Wong, Tak-ming Humphrey. "Dwelling in nature : an ecological reserve Ping Chau /." Hong Kong : University of Hong Kong, 1996. http://sunzi.lib.hku.hk/hkuto/record.jsp?B25955226.
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Puniani, Evaloni Takavaha. "Novel natural product based anti-anxiety therapy and natural insecticides." Thesis, University of Ottawa (Canada), 2004. http://hdl.handle.net/10393/29155.
Full textAbstract:
The EtOH extracts of the leaves of Margraviaceae, a relatively rare Central American vine for which ethnobotanical reports suggested possible anti-anxiety properties, showed significant anti-anxiety activity in animal models for anxiety. Subsequent bioassay-guided fractionation of these extracts yielded an EtOAc active fraction (f1). Further bioassay-directed chromatography of (f1), led to the isolation of betulinic acid (3) as the bioactive constituent in 0.01% of dry weight. Six known pentacyclic triterpenoids [( 1a), (1b), (2a), (2b), ( 4), (5a)], six known flavonoids [(6), ( 7), (8a), (8b), (9), ( 10)], chondrillasterol (11), linolenic acid (12 ) and a porphyrin type compound (13) were also isolated.
When (3) was administered at 0.5 mg per kg (possibly less) in a variety of rat and mouse model assays, the activity of (3) was comparable to that of Valium, the most famous member of the benzodiazepines family.
Synthetic derivatives of (3) were prepared and evaluated for anti-anxiety activity. Several of the simple esters appear to have ideal properties as new drug Candidates. In particular, betulinic acid methyl ester or methyl betulinate (3a) exhibited anti-anxiety activity superior to (3). The activity profile of (3a) is such that (3a) can be considered a viable drug candidate.
An excellent relay synthesis of (3) from another closely related natural product betulin (14), that is abundantly available in Eastern Ontario, was developed.
Radioactive 3H-labelled betulinic acid methyl ester ( 3a″) was also prepared in order to facilitate identification of relevant anti-anxiety receptors and the mechanism of action of the compound. This is important since (3) showed no significant binding to any of the 40 anti-anxiety receptors currently implicated in anxiety. Therefore, it appears to act as an anti-anxiety agent via a new mode of action.*
In a second project, the active components of a member of the Piperaceae or Pepper family (P. tuberculatum) from Costa Rica, were isolated and their structures characterized as 5,6-dihydropiperlonguminine (25), 5,6-dihydropiperine (26), piperine ( 27) and piperlonguminine (28).
Extracts from this neotropical plant had been previously demonstrated by our biology collaborators, Professor Arnason's group, to be strongly insecticidal towards a variety of pests including mosquitoes, earwigs and white grubs. Moreover, the P. tuberculatum extracts were as effective as the well-documented Asian (P. nigrum) and African ( P. guineense) Piper species.
Piperamides (25)--(28) were synthesized in sufficient amounts to allow extensive evaluation of their insecticidal properties. Experiments with these piperamides showed that the tertiary and quaternary mixtures have greater-than-additive toxicity compared to single compounds or binary mixtures. That is, these piperamides synergize each other. Compound (25) was the most acutely toxic in mosquito larvae bioassays. The field trials to date indicate a high potential for the development of an effective, relatively inexpensive botanically based insecticide.
Radioactive 3H-labelled piperine (27″ ) was also synthesized for toxicokinetic studies.
*Please refer to dissertation for diagrams.
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Vaclavik, Casey. "Attracting Applicants Naturally| The Effects of Natural Elements in the Workplace." Thesis, Southern Illinois University at Edwardsville, 2018. http://pqdtopen.proquest.com/#viewpdf?dispub=10789893.
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The purpose of this study was to examine if natural elements would act as identity markers and affect workplace attitudes. Specifically, the study hypothesized that a workplace environment that possessed natural elements such as natural lighting, potted plants and pictures of nature, would cause job applicants to report higher levels of organizational attractiveness and job pursuit intentions after a workplace tour of the organization. It was also hypothesized that enjoyment of nature would moderate the effect of the natural elements on these workplace attitudes. When tested with a 2x2 MANOVA, one hypothesis was supported and showed natural elements in the workplace can affect a job applicant’s organizational attraction. Implications, limitations and future research are discussed.
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Nelson, Andrew Wyatt. "Naturally occurring radioactive materials associated with unconventional drilling for natural gas." Diss., University of Iowa, 2016. https://ir.uiowa.edu/etd/5579.
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As unconventional drilling has emerged as a major industry in the US and around the world, many environmental health and pollution risks have surfaced. One emerging concern is the risk of environmental contamination arising from unconventional wastes that are enriched in naturally-occurring radioactive materials (NORM). Although NORM has been a well-documented contaminant of oil and gas wastes for decades, there are new challenges associated with unconventional drilling. This thesis discusses several of these challenges, focusing on NORM from black shale formations. Chapter 1 provides background information on environmental radioactivity and unconventional drilling. Chapter 2 describes the potential for NORM to migrate into groundwater around unconventional drilling operations. Chapters 3 and 4 describe radiochemical methods developed for the analysis of Marcellus Shale unconventional drilling wastes. Chapter 5 describes environmental partitioning of Marcellus Shale unconventional drilling wastes. Collectively, this thesis attempts to broaden the scientific understanding of NORM in unconventional drilling wastes so that potential environmental impacts may be mitigated.
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Byrd, Lawrence Allen. "The public land manager in collaborative conservation planing: a comparative analysis of three case studies in Montana." Diss., [Missoula, Mont.] : The University of Montana, 2009. http://etd.lib.umt.edu/theses/available/etd-06122009-134838.
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Svensson, Filip. "Tolkien's Natural Pathos." Thesis, Linnéuniversitetet, Institutionen för språk och litteratur, SOL, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-6585.
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Bobick, Aaron F. "Natural Object Categorization." Thesis, Massachusetts Institute of Technology, 1987. http://hdl.handle.net/1721.1/6964.
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This thesis addresses the problem of categorizing natural objects. To provide a criteria for categorization we propose that the purpose of a categorization is to support the inference of unobserved properties of objects from the observed properties. Because no such set of categories can be constructed in an arbitrary world, we present the Principle of Natural Modes as a claim about the structure of the world. We first define an evaluation function that measures how well a set of categories supports the inference goals of the observer. Entropy measures for property uncertainty and category uncertainty are combined through a free parameter that reflects the goals of the observer. Natural categorizations are shown to be those that are stable with respect to this free parameter. The evaluation function is tested in the domain of leaves and is found to be sensitive to the structure of the natural categories corresponding to the different species. We next develop a categorization paradigm that utilizes the categorization evaluation function in recovering natural categories. A statistical hypothesis generation algorithm is presented that is shown to be an effective categorization procedure. Examples drawn from several natural domains are presented, including data known to be a difficult test case for numerical categorization techniques. We next extend the categorization paradigm such that multiple levels of natural categories are recovered; by means of recursively invoking the categorization procedure both the genera and species are recovered in a population of anaerobic bacteria. Finally, a method is presented for evaluating the utility of features in recovering natural categories. This method also provides a mechanism for determining which features are constrained by the different processes present in a multiple modal world.
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Marquez, Jessica. "A natural history /." Online version of thesis, 2008. http://hdl.handle.net/1850/6249.
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Woods, Katherine B. "Bioactive natural products." Thesis, University of British Columbia, 2010. http://hdl.handle.net/2429/26234.
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Montbretins A-E were isolated from the corms of Crocosmia sp., an invasive perennial
plant. The montbretins are inhibitors of human pancreatic α-amylase (HPA). Montbretin A (2-
30) is a competitive inhibitor of HPA with a K₁ of 1.3 nM. The activity of the other family
members varied significantly and provided structure-activity information. Saturation Transfer
Difference (STD) NMR spectroscopy was used to determine that the caffeic acid region of the
montbretins is important for binding. HPA is involved in the breakdown of complex
carbohydrates; inhibition of this enzyme could help with regulation of blood sugar levels after a
meal.
In the lungs of cystic fibrosis patients, the activation of Toll-Like Receptor 5 (TLR5) in
the presence of flagellin leads to inflammation and obstruction. Girolline (3-1), a known
alkaloid, was isolated from a Phonpeian sponge following potent inhibition of the flagellin
initiated TLR5 activation. No activity was observed in any synthetic analogues of girolline. The massacreones are a new family of ecdysteroids isolated from an unidentified Dominican
cnidarian. The extract of the cnidarian had good TLR5 activity, but the massacreones – namely
massacreone A (3-25) and massacreone B (3-26) have only moderate activity and a small
window of activity before they are toxic.
The algal pigment caulerpin (4-29) was isolated from Caulerpa sp. as a compound
showing good activity in a yeast growth restoration assay designed to identify inhibitors ofhuman indoleamine-2,3-dioxygenase (IDO). Caulerpin did not show any activity in a free enzyme IDO assay. IDO is involved in immune escape, which prevents the immunological rejection of tumors.
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Wallaker, Mark. "Unconventional Natural Resources." Thesis, Uppsala universitet, Geofysik, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-226068.
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Li, I. C. K. "Natural product syntheses." Thesis, University of Southampton, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.375675.
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Craske, Simon. "Natural image segmentation." Thesis, University of Bristol, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266990.
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Aravena, M. Claudia, V. Álvaro Ovando, and C. Eduardo Ramírez. "Pastora cerveza natural." Tesis, Universidad de Chile, 2009. http://www.repositorio.uchile.cl/handle/2250/111558.
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Plan de Marketing para optar al grado de Magíster en MarketingNo disponible a texto completo
Podemos afirmar que en la industria de las cervezas artesanales en Chile se presenta una oportunidad de negocios que no ha sido considerada hasta este momento por los actores participantes. Logramos identificar que por razones económicas, culturales, de salud, de hábitos y preferencias de consumo de bebidas alcohólicas, las mujeres profesionales tienen un interesante potencial de crecimiento y que no cuenta con un producto diseñado especialmente para cubrir sus necesidades especificas. Las marcas que se consideraron como competidoras, dirigen en general todos sus esfuerzos de marketing al segmento masculino. Y las variables que diferencian las marcas tienen relación con conceptos de lo “Puro” y lo “Gourmet”. En este escenario irrumpe nuestro producto que, diseñado a partir de información obtenida de testeo ciego, focus group, encuestas y prueba de concepto, es el primero en atender la categoría de las cervezas artesanales en el segmento femenino. Es decir, logra incorporar una nueva variable que denominamos “Feminidad” y que dará a nuestra marca una posición única en la mente de los consumidores. Como marca hemos optado por Pastora. Este nombre logra asociaciones con lo femenino, lo natural (que se deriva del propio nombre) y combina perfectamente lo tradicional con la sofisticación de quienes buscan productos diferentes. Asociado a la marca se encuentra el slogan “Cerveza Natural” que reafirma las características de pureza y salud que buscaremos transmitir a través de nuestra comunicación. Existen dos variedades del producto. Pastora Rubia, cerveza lager de tipo Pilsner, que destaca por su frescura y aroma. Pastora Negra, cerveza tipo Stout que destaca por su mayor cuerpo y sabores achocolatados. Ambas cervezas son aptas para el maridaje y se comercializarán en botellas individuales de 330 cc. En cuanto a la distribución del producto, luego de analizar los hábitos del segmento objetivo y el posicionamiento buscado por la marca, se optó por los siguientes canales: bares y pubs (Pastora para momentos de relajo y esparcimiento); restaurantes (Pastora gourmet, para maridar); hoteles (busca posicionar a Pastora como una cerveza de calidad en un público en tránsito, pero conocedores de cerveza); emporios (podrán ser adquiridas y consumida en casa como un producto de calidad, certificado implícitamente) e Internet (canal de comunicación y distribución directa). Para establecer el precio del producto, nos basamos en los estudios realizados a los potenciales consumidores, en los precios establecidos por los competidores, en nuestra estrategia de posicionamiento y, por ende, en la imagen que buscamos transmitir de Pastora. Diferenciamos precios, dependiendo del canal de distribución. El consumidor final enfrentará precios más altos (que fluctuarán entre $2.000 y $2.500) en restaurantes, bares, pubs y hoteles, un precio intermedio de $1.500 en emporios y un precio unitario de $1.190 más los gastos de envío en el canal web, donde adicionalmente se incluirán ciertos descuentos por volumen. También se realizarán promociones a los distintos canales para gestionar la estacionalidad del consumo. En la promoción de nuestro producto, se realizarán distintas acciones de comunicación buscando como objetivo lograr conciencia del producto, conocimiento, recordación y agrado. Aunque el objetivo principal es llegar a un nivel de conocimiento de 60% en el target en un plazo de 6 meses desde el lanzamiento del producto. Para lograr estos objetivos se incluirán avisos en revistas femeninas y revistas especializadas en temas gourmet. Además recurriremos a Internet, a través de distintas iniciativas como: la utilización del sitio web de Pastora para una comunicación bidireccional con los clientes, la utilización de Facebook de la marca, de Newsletter a través de e-mailing, el uso de banners, AdSense y blogs especializados. Las relaciones públicas serán de nuestro especial interés porque buscamos generar un poderoso boca a boca, por lo que se desarrollarán diversas actividades entre las que destaca un importante lanzamiento, un circuito de catas, kit de prensa y entrevistas. Por último, el merchandising también será considerado al momento de comunicar nuestra marca.
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Costa, Francisco Pedro de Carvalho Santos. "A infraestrutura natural." Master's thesis, Universidade de Lisboa, Faculdade de Arquitetura, 2018. http://hdl.handle.net/10400.5/17498.
Full textAbstract:
Dissertação de Mestrado Integrado em Arquitetura, com a especialização em Arquitetura apresentada na Faculdade de Arquitetura da Universidade de Lisboa para obtenção do grau de Mestre.O presente trabalho propõe uma reflexão crítica acerca do rio Arade, na região do Algarve, e sua relação com as populações envolventes. Um rio que outrora serviu como o principal eixo de ligação e comunicação de pessoas e produtos entre a foz e Silves, revê-se hoje relegado ao esquecimento. Perante uma paisagem algo negligenciada, procurou-se lançar bases para um reconhecimento e reactivação do território. Ao longo do rio podem ser encontradas estruturas vernáculas que representam memórias de tempos em que o rio era um dos meios de sustento da região. Estruturas estas ligadas às diferentes actividades de produção que marcavam o quotidiano das populações. A infraestrutura natural - O rio Arade como estrutura de (re) conexão e dinamização do território -, ganha forma como proposta de reactivação do eixo de outrora, onde o desenho arquitectónico abre o caminho para a reinterpretação do território, através da criação de percursos que o relacionam com a margem, ao passo que unem a paisagem e o património, celebrando e preservando a sua história.
ABSTRACT: The present work proposes a critical reflection over the Arade River, in the Algarve region, and its relationship with the surrounding populations. A river that once served as the main axis of connection and communication for people and products between the river mouth and Silves, is today relegated to oblivion. Standing before a somewhat neglected landscape, comes an attempt to lay a basis for the recognition and reactivation of the territory. Following the river we can find vernacular structures that mirror past time memories, of when the river was one of the livelihoods of the region. These structures are linked to the different production activities that punctuated the daily lives of the populations. The natural infrastructure - the Arade river as a structure of (re)connection and invigoration of the territory -, takes shape as a proposal to reactivate the axis of yesteryear, where the architectural design opens the way for the reinterpretation of the territory, through the creation of paths that relate it to its margin, while uniting the landscape and the heritage, celebrating and preserving its history.
N/A
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Rivera, H. Marcelo. "Isotónico deportivo natural." Tesis, Universidad de Chile, 2011. http://www.repositorio.uchile.cl/handle/2250/113685.
Full textAbstract:
Tesis para optar al grado de Magíster en MarketingNo disponible a texto completo
Sé que la Industria de los Bebestibles y la Industria de los Isotónicos es Chile, es una Industria atractiva y muy competitiva, que se encuentra en pleno crecimiento, lo cual la hace más dinámica y competitiva aún, es esa industria donde propongo un plan de marketing estricto que permita efectuar con éxito un lanzamiento de un nuevo producto, pero no es menos cierto que para introducir este nuevo producto se debe contar con un plan creativo, pero por sobre todo efectivo en todas las variables del marketing mix. Para poder conocer el resultado de este plan es que los invito a conocer los objetivos que he propuesto y el desarrollo del Marketing Mix, con énfasis en el punto comunicacional.
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Pipes, Todd David. "A Natural History." Thesis, University of North Texas, 1994. https://digital.library.unt.edu/ark:/67531/metadc500317/.
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A Natural History is a collection of original poetry written over the past three years. This project represents a period of learning and growth, as well as a concentrated effort to develop an individual writing style and voice grounded in the most enduring poetic values of the past.
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Hilton-Hagemann, Brandi L. "Natural born enemies?" Laramie, Wyo. : University of Wyoming, 2008. http://proquest.umi.com/pqdweb?did=1594498531&sid=1&Fmt=2&clientId=18949&RQT=309&VName=PQD.
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MacCartney, Bill. "Natural language inference /." May be available electronically:, 2009. http://proquest.umi.com/login?COPT=REJTPTU1MTUmSU5UPTAmVkVSPTI=&clientId=12498.
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Cerrate, Paredes Julio Andre Joseph, Barzola Cinthia Sandy Hidalgo, Lazo Carol Lorena Llerena, and Quiliche Jessica Mendoza. "Cosmética Natural Care." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2019. http://hdl.handle.net/10757/626328.
Full textAbstract:
El presente trabajo de investigación trata acerca de la viabilidad del modelo de negocio Natural Care que es una línea de cosmética natural compuesto por jabón líquido, tónico exfoliante, crema facial y crema corporal para el cuidado de la piel que son elaboradas a base de plantas, frutos y cereales oriundos del Perú, que contienen propiedades: antioxidante, colágeno y omega, libre de parabenos.
Por tal motivo, se realizó un estudio de mercado en el segmento de consumidores que son mujeres de la generación Millennial de 25 a 39 años de edad del NSE A, B y C que residen en los distritos de la zona 7 de Lima Metropolitana, quienes afirmaron que la cosmética convencional tiene componentes químicos, por ello, si estarían dispuestas a usar cosmética 100% natural porque les genera mayor confianza para el cuidado y salud de su piel.
Además, según los resultados de la investigación se obtuvo que el mercado meta es de 8,533 mujeres dispuesta a comprar los productos Natural Care con una frecuencia de 2 veces al mes, lo cual, indica que el negocio tiene oportunidades de desarrollo y crecimiento a nivel local y regional, ya que en Latinoamérica está en crecimiento la tendencia de consumo de productos naturales para el cuidado de la piel.
Por tal motivo, se necesita una inversión de 78,556 soles para el financiamiento del proyecto, lo cual, se tiene planificado financiar el 50% con capital propio y el otro 50% apalancarse con deuda proveniente de un capital externo.This research paper is about the viability of Natural Care’s business model. Natural Care is a line of natural cosmetics that offers products such as liquid soap, exfoliating tonic, face and body cream for skin care; every product is made from plants, fruits and cereals native to Peru, which contain antioxidant properties, collagen and omega, free from parabens. Due to the research, a market study was conducted in a segment of consumers who are Millennial women from 25 to 39 years, A, B and C socioeconomic status, who reside in districts of zone 7 Metropolitan Lima. They affirmed that conventional cosmetics have chemical components, therefore, they would be willing to use 100% natural cosmetics, because they would feel more confident about these products for skin care and health. In addition, according to the results of this research, it was found that the target market is 8,533 women willing to buy Natural Care products twice a month, which indicates that the business has opportunities for development and growth at local and regional levels, since in Latin America the trend of consumption of natural products for skin care. For that reason, an investment of 78,556 soles is needed to the project, which is planned to be financed by 50% of its own capital and the other 50% will be leveraged with debt from external capital.
Trabajo de investigación
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Pereira, Diana Garcia. "Coexistir." Master's thesis, Universidade de Lisboa, Faculdade de Arquitetura, 2018. http://hdl.handle.net/10400.5/16771.
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Dissertação de Mestrado Integrado em Arquitetura, com a especialização em Arquitetura apresentada na Faculdade de Arquitetura da Universidade de Lisboa para obtenção do grau de Mestre.O presente exercício parte da inquietação e reflexão de como o ser humano, ao longo dos tempos, se foi distanciando e elevando sobre todos os outros seres vivos e elementos naturais que compõem o nosso planeta. É a partir desta preocupação e elucidando o comprometimento das gerações futuras, que, com base num pensamento filosófico, se procura dar a perceber que a Natureza está em toda a parte e que nós, os humanos, somos uma parte ínfima de um enorme sistema vivo com o qual necessitamos e devemos coexistir. Conscientes daquilo que somos, é a partir da condição topográfica de vale, no sítio de Xabregas, onde encaixa um plano de fundo pós-industrial, que a proposta, tanto à escala urbana como à escala do edificado, partirá da coesão entre nós e todos os outros elementos que compõem intrinsecamente o território. É nesta linha de pensamento que se propõe a aplicação dos cincos pontos da sustentabilidade – a localização, o desenho passivo, a água, os materiais e a energia. A ideia de poder coexistir, numa área tão perto de centro de Lisboa, em articulação com a introdução de novos usos, que nascem para complementar as já existentes atividades do lugar, permitirão, a diferentes escalas, redesenhar coerentemente o território, dinamizando novas vivências que atraiam a população a viver o exterior, apelando, ao mesmo tempo, ao funcionamento natural do lugar.
ABSTRACT: The exercise put forth arises from the restlessness and thinking of how, throughout the passage of time, the human being was able to stand apart from all the other living beings and natural elements that make up our planet. It is from the concern surrounding this subject, and clarifying the commitment of future generations, that, with grounds on philosophical thinking, it is sought to convey that Nature is everywhere and that us, the human beings, are an insignificant part of an overwhelming living system, with which we need and ought to coexist. Being aware of what we are as human beings, it is from the topographical condition of valley in the site of Xabregas, where it is present a post-industrial background, that the proposal, both at the urban and the built scale, will arise from the cohesion between us human beings and all the other elements that intrinsically form the territory. It is through this line of thought that the application of the five sustainability points is proposed – the localization, the passive design, the water, the materials and the energy. The idea of being able to coexist, in an area so close to the Lisbon centre, in articulation with the introduction of new uses, born to complement the site’s already existing activities, will allow to coherently redesign the territory at different levels, dynamizing new experiences that attract the population to make the most of the outdoors, while at the same time appealing to the natural functioning of the site.
N/A
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Bringans, Scott D. "Studies on natural product derivatives : HIV therapies incorporating marine natural products." Thesis, University of Canterbury. Chemistry, 2001. http://hdl.handle.net/10092/6699.
Full textAbstract:
CV-N is an 11 kDa, anti-HIV protein that binds strongly to the envelope glycoprotein, gp120, expressed on the outer surface of the free virion and also on HIV-infected cells. As such, it represents an important lead for development of anti-HIV therapeutics. Marine toxins such as the halichondrins have potent in vivo cytotoxicities and are lethal to cells. The combination of this potency of the marine toxins with the unique targeting capability of CV-N has been harnessed to produce conjugates that have the potential to selectively target and eliminate HIV-infected cells.
Three forms of the protein were developed; the native protein itself, a derivative recombinantly produced in E. coli with an extra cysteine at the C-terminal (CV-N-Cys) and CV-N with the lysine side chain amines converted into thiols (thiolated-CV-N).
To facilitate release of the toxin within infected cells an enzymatically-cleavable pHdependent biolinker was incorporated separating the toxin from the protein. The chemistry required for incorporation of protein, biolinker, and toxin, was established through synthesis of fluorescently labelled conjugates capable of reaction with CV-N. Biological testing of these derivatives showed no interference with the anti-HIV activity of the CV-N when conjugated in these model compounds. Synthetic strategies were developed to produce two derivatives of norhomohalichondrin B amine, both containing the cleavable biolinker, but with activation from succinimidyl esters and maleimido groups respectively.
Native CV-N was reacted with the succinimidyl ester derived toxin construct to produce a CV-N-biolinker-toxin conjugate. The maleimido derivative toxin construct was reacted with both CV-N-Cys and thiolated-CV -N to produce closely related CV-N-toxin conjugates. Investigations into the binding properties and cell toxicities of these conjugates is currently underway.
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Jensen, Mari N. "UA Licenses Patent for Natural Fungicide: Natural Product Fights Plant Diseases." College of Agriculture and Life Sciences, University of Arizona (Tucson, AZ), 2005. http://hdl.handle.net/10150/622198.
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Ting, Hung Yun, and 洪韵婷. "Natural Naturally Exist." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/49915399914226870350.
Full textAbstract:
碩士國立臺灣藝術大學
造形藝術研究所
94
In this assignment, it will present you the development of my practical work and the understanding from the readings, which is related to my project. From the point of view of going through the world that we can see, it mainly focuses on the thing, which exists in our daily life and the imagination, which exists in our mind. For me, artwork is the representation coming from the wonderful illusion and imagination, in that order, artwork will go into the field of itself to realize the power of “retentir”, and especially escape the influence from the mainstream issues. Artwork will have its own dialogue with the audience directly and it will show you the condition of nature and natural existence in a simple way without any explanations.
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DI, GIACOMO SILVIA. "Natural and naturally-derived compounds as new chemopreventive agents." Doctoral thesis, 2014. http://hdl.handle.net/11573/538397.
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Chemoprevention is an approach based on the use of natural or synthetic compounds to inhibit, suppress or reverse the development and progression of cancer. In order to overcome the cancer disease, the identification of chemopreventive compounds is of particular interest. Among them, antimutagens prevent the mutagen-induced DNA-injury or promote the repair and/or the reversion of damage. In addition to antimutagenicity, some agents also act as chemosensitizers, by increasing the effectiveness of cancer chemotherapy and radiotherapy, when used in combination with chemotherapeutical agents. This approach is very interesting to prevent the development of multidrug resistance (MDR), which makes cancer cells not-sensitive to a broad range of drugs. In this context, present study was aimed at evaluating the potential chemopreventive properties of some natural and naturally-derived compounds, particularly the sesquiterpenes β-caryophyllene (CRY) and β-caryophyllene oxide (CRYO), and the aldehyde α-hexylcinnamal (HCA). The antimutagenic activity was evaluated by the reverse bacterial mutation assay (Ames test), on different strains of Salmonella typhimurium and Escherichia coli, both in absence and presence of the S9-metabolic activation system. As mutagens, 2- nitrofluorene (2NF), sodium azide (SA), methyl methanesulfonate (MMS), 2-aminoanthracene (2AA), benzo[a]pyrene (BaP), 4-nitroquinoline N-oxide (4NQO), 1-nitropyrene (1NP), 1,8-dinitropyrene (1,8-DNP) and a sample of condensed smoke (CSC) from standard 3R4F cigarette were used. In addition to antimutagenicity studies, the potential chemosensitizing properties of CRY, CRYO and HCA and their ability to interfere with ABC-transporter function were evaluated, in Caco-2, CEM/ADR5000 and CCRF/CEM human cancer cells. For each compound, low concentrations (IC10 and IC20) were assayed in order to verify their potential additive, synergistic or antagonistic effects with the anticancer doxorubicin. The nature and the extent of the interaction were evaluated by the combination index (CI) and the isobologram analysis, respectively; conversely, the potential enhancement of drug effectiveness was quantified by cytotoxicity enhancement ratio (RR). The interaction between test compounds and ABC-transporters was studied by the rhodamine 123 assay. HCA exhibited an antimutagenic activity against different nitro-compounds and in various experimental protocols, suggesting the involvement of both desmutagenic and bioantimutagenic mechanisms. The sesquiterpenes CRY and CRYO resulted able to inhibit the mutagenicity of CSC, although with different potency and specificity: CRYO was the most potent compound, acting at concentrations about ten-times lower than CRY. The antimutagenicity was highlighted in different strains and in all experimental protocols, suggesting the overlapping of various protective mechanisms; the inhibition of CSC-induced oxidative stress seems to be likely and deserves further investigations. In human cancer cells, the substances produced cytotoxic effects at high concentrations both in resistant and in sensitive cell lines: HCA was the most effective substance, especially in the sensitive CCRF-CEM cells. All the compounds synergistically acted with doxorubicin, although HCA was the most potent: IC20 HCA increased the doxorubicin cytotoxicity of about six, seven and fourthy-seven folds, in Caco-2, CEM/ADR5000, and CCRF-CEM, respectively. In addition, a remarkable inhibition of ABCtrasporter was produced by HCA in the cancer cells tested: the effect was higher than that of the standard inhibitior verapamil. Also CRY and CRYO inhibited the ABC transporters but with lower potency than verapamil. The antimutagenic and chemosensitizing properties of β-caryophyllene, β-caryophyllene oxide and the α-hexylcinnamaldehyde deserves attention and represent a starting point to better evaluate their potential applications in the field of chemoprevention.
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Quan, Line Zhao, and 林召荃. "Natural Ecological Activities Involved In Natural Music Preference." Thesis, 2014. http://ndltd.ncl.edu.tw/handle/36798841308123617838.
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碩士國立臺南大學
生態科學與技術學系生態旅遊碩士班
102
The music with nature soundscapes has become rather popular recent years. Therefore, the purpose of this research was to explore how natural-environment-related activities determine individuals’ music preference. Taking factors such as wildlife-and-nature activities, information, group-activities, as well as travelling engagement in natural surroundings into consideration, this study applied McIntire and Pigram (1992) involvement theory and its assessment scale to verify the cause-and-effect relationship between involvement of outdoor activities and the music preference. Based on the references, this study provided a hypothesis. Participants of this research, which was conducted by using Internet questionnaires with au audio attachment, were all Internet users, and 476 snowball samples. This paper utilized Structure Equation Models (SEM) for statistical analysis method to verify the hypothesis. According to the analysis result, it turned out that there is a cause-and-effect relationship between the centrality aspect of activity involvement theory and the music preference, and centrality aspect is with a connotation that life style is associated with wildlife-and-nature activities such as sharing with friends about wildlife-and-nature activities or enjoyment of visiting natural surroundings, etc. On the other hand, this study showed that aspects of attraction and self-expression have no impact on music of nature. This research was an advocate of Cross & Morley (2006) theory of music behavior, that is, music behavior is associated with individuals’ social functioning.
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Bailey, Thomas. "Natural history." Thesis, 2020. https://hdl.handle.net/2144/41850.
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Please note: creative writing theses are permanently embargoed in OpenBU. No public access is forecasted for these. To request private access, please click on the lock icon and fill out the appropriate web form.2031-01-01T00:00:00Z