Journal articles on the topic 'National Health and Medical Research Council (Australia)'
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Mccloskey, Ian. "Funding of medical research in Australia by the National Health & Medical Research Council." Higher Education 28, no. 1 (July 1994): 137–46. http://dx.doi.org/10.1007/bf01383578.
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Grogan, P. "Bowel Cancer Screening in Australia: Research and Tactics to Achieve an Advocacy Goal." Journal of Global Oncology 4, Supplement 2 (October 1, 2018): 145s. http://dx.doi.org/10.1200/jgo.18.14500.
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Background and context: Bowel cancer is the second leading cause of cancer death in Australia, yet survival is above 90% if it is detected at stage one. Cancer Council Australia has advocated since 1997 (when RCT evidence was published) for a national government-run screening program—a challenge to any government, given the costs and changes across the health system, irrespective of the health benefits. Cancer Council Australia has advocated at every step in the program’s development, from pilot studies to securing bipartisan political support for the program´s introduction to funding allocations linked to our budget submissions. Yet cost pressures restricted the Australian Government in 2013 to implementation by 2034 - an unacceptable timeframe in view of preventable deaths over that period. To find a peer-reviewed “big number” to convince candidates in Australia´s 2013 federal election to support full implementation by 2020, Cancer Council commissioned a study of multiple screening scenarios submitted to a leading medical journal, showing our implementation plan would prevent 35,000 bowel cancer deaths by 2040. The incoming government, despite campaigning on national debt-reduction, allocated almost $100 million dollars—the centrepiece of its first health budget—to Cancer Council Australia´s plan, attributing the decision to our advice. Subsequent Cancer Council Australia research has shown the program´s life-saving benefits to be even greater if participation can be increased, and that it would achieve net savings. We continue to push for program promotion, with our peer-reviewed research showing 60% participation would prevent 84,000 bowel cancer deaths by 2040. Aim: To highlight how political advocacy and scientific research can work together by ensuring the advocacy is based on the best available evidence, with that evidence collected through a peer-reviewed study designed to deliver major policy reform. Strategy/Tactics: The key strategy/tactics were basic but often overlooked: collect the most compelling evidence of benefit, thereby making it difficult for politicians to dismiss the advocacy. The example of bowel cancer screening advocacy in Australia since 2012-13 has been presented in Australian research institutes to highlight how studies can be designed expressly to translate to a major policy outcome. Program/Policy process: Cancer Council Australia adhered to all government processes within its advocacy remit (budget submissions, being appointed to government committees, producing clinical practice guidelines) while working independently to drive the research and public policy agenda. Outcomes: The accelerated implementation of a landmark national screening program. What was learned: That even politicians obsessed with budget cuts can´t always argue with the best evidence—and that researchers can design studies that change policy and practice, if guided by political pragmatists.
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Bagatini, Simone Radavelli, Marc Sim, Lauren Blekkenhorst, Nicola Bondonno, Catherine Bondonno, Richard Woodman, Joanne Dickson, et al. "Associations of Specific Types of Fruit and Vegetables with Perceived Stress in Adults: The AusDiab Study." Current Developments in Nutrition 6, Supplement_1 (June 2022): 943. http://dx.doi.org/10.1093/cdn/nzac067.063.
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Abstract Objectives Prolonged exposure to stress is a risk factor for mental and physical health problems (i.e., depression, cardiovascular disease). Although higher consumption of fruit and vegetables (FV) has been associated with lower perceived stress (PS), the relationship between specific FV types and PS remains uncertain. The aim of this cross-sectional study was to explore the relationship between consumption of specific FV types with PS in a cohort of men and women aged 25–92 years who took part in the Australian Diabetes, Obesity and Lifestyle (AusDiab) Study. Methods A validated Food Frequency Questionnaire was used to assess dietary intake (n = 8,640). A validated questionnaire was used to assess PS (high PS cut-offs were obtained from the highest quartile of PS for each sex). Multivariable-adjusted logistic regression was performed to investigate the associations. Results The mean age of participants (50.1% females) was 47.8 (SD 15) years. Those in the highest quartiles of apples and pears, orange and other citrus, and banana intakes had a significantly lower odds (24–31%) of having high PS, compared to lowest. Similarly, those with higher intakes of cruciferous, yellow/orange/red, and legume vegetables had significantly lower odds (25–27%) of having high PS. Conclusions In Australian adults, a higher consumption of different types of FV may alleviate stress and potentially improve mental and physical wellbeing. Funding Sources This study received no specific grant from any funding agency in the public, commercial or not-for-profit sectors. The salary of MS and CPB is supported by a Royal Perth Hospital Research Foundation Career Advancement Fellowship. The salary of LCB is supported by a National Health and Medical Research Council (NHMRC) of Australia Emerging Leadership Investigator Grant and a National Heart Foundation of Australia Post-Doctoral Research Fellowship. The salary of JRL is supported by a National Heart Foundation of Australia Future Leader Fellowship. The salary of JMH is supported by a National Health and Medical Research Council of Australia Senior Research Fellowship. The salary of JES is supported by a National Health and Medical Research Council Investigator Grant. None of the funding agencies had any role in any aspects of the manuscript.
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KIDD, Timothy J., Guy B. MARKS, Peter T. P. BYE, Claire E. WAINWRIGHT, Philip J. ROBINSON, Barbara R. ROSE, Colin HARBOUR, and Scott C. BELL. "Multi-centre research in Australia: Analysis of a recent National Health and Medical Research Council-funded project." Respirology 14, no. 7 (September 2009): 1051–55. http://dx.doi.org/10.1111/j.1440-1843.2009.01595.x.
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Henderson, A. S. "The NH & MRC Social Psychiatry Research Unit, at the Australian National University, Canberra, 1975–90." Psychological Medicine 21, no. 1 (February 1991): 245–54. http://dx.doi.org/10.1017/s0033291700014835.
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In 1974, the National Health and Medical Research Council (NH & MRC) in Australia reviewed what initiatives might be undertaken to promote medical research relevant to the needs of the population. It noted that Australia had contributed with distinction in some areas, such as the neurosciences and immunology, whereas fields such as epidemiology and psychiatry were much less developed scientifically. As the principal source of funding for medical research, the NH & MRC had hitherto supported projects, individuals and a small number of institutions (e.g. the Walter and Eliza Hall, the Florey and the Baker Institutes). The initiative adopted in 1974, as an additional commitment, was to establish some research units in areas of major relevance for public health. These were intended to become centres of excellence in fields where more expertise was needed at a national level.
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Kirkman, Noreen. "Article processing charges and fully open access journals: National Health and Medical Research Council funded articles." Journal of Health Information and Libraries Australasia 2, no. 3 (December 20, 2021): 39–56. http://dx.doi.org/10.55999/johila.v2i3.85.
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Introduction: The National Health and Medical Research Council, Australia’s largest medical research funder, mandates open access for journal articles published from funded research. Publishing articles in fully open access journals is an acceptable route to achieve compliance. However, the total cost of article processing charges and the extent to which Council funds contribute to payment are unknown.Objectives: The main objectives of this study were to calculate the cost of article processing charges and determine the extent of acknowledgement of payment for Council-funded articles published in fully open access journals during 2019.Methods: The funding acknowledgement fields of Web of Science provided the list of Council-funded articles. The Directory of Open Access Journals identified fully open access journal titles and their article processing charges. Data analysisinvolved bibliometric research methods, principally descriptive statistics.Results: The cost of article processing charges for 2,261 articles published in 2019 was over US$5,000,000. Charges ranged from zero to US$5,200, with the median being US$1,900. The acknowledgement of payment of article processing chargeswas extremely low (1.72%).Discussion: The insufficient acknowledgement of the considerable expenditure on article processing charges is concerning. The “Australian Code for the Responsible Conduct of Research” underscores the principles of transparency in declaringinterests. Required is greater disclosure of expenditure on article processing charges and accountability for public-funded research.Conclusion: The disclosure of article processing charge payments should be mandated by the Council and included in the publication metadata deposited in repositories under the National Health and Medical Research Council’s OpenAccess Policy. Acknowledgements and disclosures are essential in recognising professional contributions and ensuring the responsible conduct of research.
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Mitchell, Heather. "The price of guidelines: revising the national guidelines for managing Australian women with abnormal Pap smears." Sexual Health 3, no. 1 (2006): 53. http://dx.doi.org/10.1071/sh05027.
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Australia utilises nationally approved guidelines for managing women with abnormal Pap smears. The guidelines were recently revised using the process designated by the National Health and Medical Research Council. Revising the guidelines was protracted and controversial. This paper explores the reasons for the difficulties encountered and queries the cost of undertaking such work.
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Crowe, B. L., and I. G. Mcdonald. "Telemedicine in Australia. Recent developments." Journal of Telemedicine and Telecare 3, no. 4 (December 1, 1997): 188–93. http://dx.doi.org/10.1258/1357633971931147.
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There have been a number of important developments in Australia in the area of telemedicine. At the national level, the House of Representatives' Standing Committee on Family and Community Affairs has been conducting the Inquiry into Health Information Management and Telemedicine. The Australian Health Ministers' Advisory Council has supported the establishment of a working party convened by the South Australian Health Commission to prepare a detailed report on issues relating to telemedicine. State governments have begun a number of telemedicine projects, including major initiatives in New South Wales and Victoria and the extensive development of telepsychiatry services in Queensland. Research activities in high-speed image transmission have been undertaken by the Australian Computing and Communications Institute and Telstra, and by the Australian Navy. The matter of the funding of both capital and recurrent costs of telemedicine services has not been resolved, and issues of security and privacy of medical information are subject to discussion. The use of the Internet as a universal communications medium may provide opportunities for the expansion of telemedicine services, particularly in the area of continuing medical education. A need has been recognized for the coordinated evaluation of telemedicine services as cost-benefit considerations are seen to be very important.
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Taylor-Sands, Michelle, Malcolm Smith, Michelle King, and Harriet Fraser. "Non-Medical Sex Selection in Australia: Public Views and Bioethical Concerns." QUT Law Review 18, no. 2 (January 25, 2019): 44. http://dx.doi.org/10.5204/qutlr.v18i2.759.
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In 2017, following an extensive review of its ethical guidelines on assisted reproductive technology (ART), the Australian National Health and Medical Research Council (NHMRC) upheld its moratorium on non-medical sex selection (NMSS) pending further public debate. Interestingly, the public consultation conducted by the NHMRC revealed a majority of submissions supported a permissive approach to NMSS, suggesting a potential shift in attitudes about NMSS in Australia. Historically, public consultation on NMSS both internationally and in Australia has revealed general opposition to this practice. This has reinforced concerns raised against NMSS in bioethical debates and been reflected in a restrictive regulatory approach to NMSS in many countries. The NHMRC public consultation highlights a potential disconnect between the concerns raised about NMSS in scholarly literature and more liberal community views. This paper reviews the submissions made to the NHMRC on NMSS and argues that the current moratorium should be revisited with a view to exploring a more nuanced approach to regulating NMSS in the future.
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Tiller, KG. "Urban soil contamination in Australia." Soil Research 30, no. 6 (1992): 937. http://dx.doi.org/10.1071/sr9920937.
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The current knowledge of the pollution of Australian urban soils was reviewed with special reference to heavy metals. Increased community concern in recent years has resulted m a major upsurge in the investigation and rehabilitation of contaminated soils. This has led to a concomitant reassessment and development of regulatory procedures, and the establishment of some new environmental agencies. This review considers sources and extent of contamination, and approaches to the establishment of reference background levels in urban and rural areas. Assessment of contaminated sites has been largely based on overseas experience but site specific approaches relevant to Australian soils and climates are needed and are being developed by State authorities in collaboration with the Australian and New Zealand Environmental and Conservation Council and the National Health and Medical Research Council. The need for soil-based research and for standardized soil sampling procedures for site evaluation and action is stressed. Many opportunities exist for soil scientists in solving problems of soil contamination and rehabilitation.
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Robinson, Jo, and Jane Pirkis. "Research priorities in suicide prevention: an examination of Australian-based research 2007–11." Australian Health Review 38, no. 1 (2014): 18. http://dx.doi.org/10.1071/ah13058.
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Objective Suicide prevention, including among youth, has been a national priority in Australia for some time. Yet despite this, rates of suicide, and related behaviour, remain high. The aim of this study was to review all suicide-prevention research that had been conducted in Australia between January 2007 and December 2011, with a specific emphasis on studies relating to young people, in order to determine whether or not we are prioritising the sort of research that can adequately inform policy development and guide ‘best practice’. Methods Data were collected from two sources. First, several electronic databases were searched in October 2012 in order to identify published journal articles relating to suicide, written by Australian authors. Second, summary data obtained from the National Health and Medical Research Council, the Australian Rotary Health Research Fund and the Australian Research Council were examined in order to identify currently funded studies that relate to suicide. Studies were then classified according to whether or not they had a focus on youth, and according to research type, type of suicide-related behaviour under investigation and method of suicide. Results There were 224 articles published and 12 grants funded that specifically focussed on suicide-related behaviour over the period January 2007 to December 2011. Of these, 47 articles (21%) and five funded grants (42%) focussed on young people. Youth studies, in particular those reported in the published articles, tended to be epidemiological in nature and only six of the published articles (13%) and two of the funded grants related to intervention studies. Conclusions Although the focus on youth is welcome, the lack of intervention studies is disappointing. Given that rates of suicide and related behaviour remain high, there is a clear need for a stronger body of intervention research that can inform national policy, if we are to successfully develop effective approaches to reducing suicide risk. What is known about the topic? Although the prevention of youth suicide has been a national priority for some time, rates of suicide and suicide-related behaviour remain high among young Australians. Much is known about the epidemiology of suicide; however, relatively little is known about which interventions may be effective in reducing this risk. Previous research suggests that although youth receive a reasonable amount of research attention in Australia, the majority of studies focus on epidemiological as opposed to intervention research. What does this paper add? This paper reviews all suicide research that has been conducted in Australia between 2007 and 2011 in order to examine how much attention is currently given to studies relating to youth, and the relative priority given to intervention and epidemiological studies. Our findings support those reported previously, which suggest that although a significant proportion of suicide research focuses on youth, relatively little attention continues to be given to intervention studies. What are the implications for practitioners? This paper argues that further intervention research is needed if we are to build a sufficiently strong evidence base that can effectively inform policy development and guide best practice when it comes to preventing youth suicide in Australia.
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Budd, Alison C., and Christine J. Sturrock. "Cytology and cervical cancer surveillance in an era of human papillomavirus vaccination." Sexual Health 7, no. 3 (2010): 328. http://dx.doi.org/10.1071/sh09133.
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Cytological and cancer surveillance will provide the most effective indications of short-term effects and long-term outcomes of the introduction of the human papillomavirus (HPV) vaccine in Australia. This article outlines how this surveillance is proposed to occur through the established national monitoring mechanisms of the National Cervical Screening Program in the annual Australian Institute of Health and Welfare (AIHW) publication ‘Cervical screening in Australia’. Cytological surveillance will be possible principally through cytology data provided annually by the state and territory cervical cytology registers, and it is expected that these data will provide the earliest and most comprehensive indications of effects from the HPV vaccine. Some potential issues in interpreting these data are also discussed, including the potentially confounding effects of the introduction of new National Health and Medical Research Council guidelines ‘Screening to prevent cervical cancer: guidelines for the management of asymptomatic women with screen-detected abnormalities’ some 9 months before the introduction of the vaccine. Cancer surveillance over the long term will be possible using cervical cancer incidence data reported annually for the National Cervical Screening Program in ‘Cervical screening in Australia’ using data sourced from the Australian Cancer Database. In a final discourse, the HPV vaccine and cervical screening are discussed concurrently, and the importance of continued cervical screening in the HPV vaccine era emphasised.
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Shea, A., J. Poon, and S. Williamson. "Microbial risk assessment of drinking water to set health-based performance targets to improve water quality and treatment plant operations." Water Practice and Technology 11, no. 2 (June 1, 2016): 495–502. http://dx.doi.org/10.2166/wpt.2016.006.
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Western Water (WW) provides water, recycled water and wastewater services to almost 150,000 people whilst continuously striving to improve processes to provide its customers with safe, cost effective and reliable drinking water, recycled water and treatment services. Under this framework of continuous improvement, WW has reviewed the effectiveness of its drinking water treatment systems using quantitative microbial risk assessment (QMRA) techniques described by the World Health Organization (WHO). The microbial-related water quality targets in the Australian Drinking Water Guidelines Paper 6 National Water Quality Management Strategy (2011) National Health and Medical Research Council, National Resource Management Ministerial Council, Commonwealth of Australia, Canberra are simply ‘to ensure that drinking water is free of microorganisms that can cause disease’. Whereas, the Australian Guidelines for Water Recycling adopted the WHO QMRA approach for setting health-based microbial targets to manage health risk to customers. WW has investigated adopting the AGWR methodology for drinking water risk management, and invested in the development of a convenient and practical QMRA tool for rapid assessment and reporting of the microbial safety of its drinking water systems. This action resulted in the identification of several drinking water system performance deficiencies, and recommendations for system improvements and optimization to improve health risk management to customers.
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Thom, Ogilvie, Kym Roberts, Peter A. Leggat, Susan Devine, Amy E. Peden, and Richard Charles Franklin. "Addressing gaps in our understanding of the drowning patient: a protocol for the retrospective development of an Utstein style database and multicentre collaboration." BMJ Open 13, no. 2 (February 2023): e068380. http://dx.doi.org/10.1136/bmjopen-2022-068380.
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IntroductionThis retrospective observational study aims to create a comprehensive database of the circumstances of drowning (including care provided and outcomes of care) to report against the Utstein style for drowning (USFD) for patients presenting to the emergency department (ED). Four areas will be examined: a feasibility study of the USFD; a comparison of classification and prognostication systems; examination of indications and efficacy of different ventilation strategies; and differences in the circumstances, severity, treatment and outcomes of drowning by sex and gender.Methods and analysisThis protocol outlines retrospective data collection for all patients presenting to EDs of the Sunshine Coast Hospital and Health Service in Queensland, Australia with the presenting problem or discharge diagnosis of drowning or immersion between 2015 and 2022. Patients computerised health records (emergency medical service record, pathology, radiology results, medical and nursing notes for ED, inpatient units and intensive care units) will be used to extract data for entry into an USFD database. Descriptive (eg, median, IQR) and inferential statistical analyses (eg, analysis of variance) will be used to answer the separate research questions. Development of an International Drowning Registry using the USFD dataset and the Research Electronic Data Capture (REDCap) web application is discussed.Ethics and disseminationThis study has been approved by Metro North Human Research and Ethics Committee (Project No: 49754) and James Cook University Human Research Ethics Committee (H8014). It has been endorsed by national drowning prevention organisations Royal Life Saving Society Australia (RLSSA) and Surf Life Saving Australia (SLSA). Study findings will provide data to better inform clinical management of drowning patients and provide an evidence base on sex and gender differences in drowning. Results will be disseminated through peer review publications, conference presentations and media releases. Results will also be disseminated through RLSSA and SLSA membership of the Australian and New Zealand Resuscitation Council and the Australian Water Safety Council.
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Antioch, Kathryn M., and Michael K. Walsh. "A new ambulatory classification and funding model for radiation oncology:Non-admitted patients in Victorian hospitals." Australian Health Review 21, no. 1 (1998): 62. http://dx.doi.org/10.1071/ah980062.
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62The Victorian Department of Human Services has developed a classification andfunding model for non-admitted radiation oncology patients. Agencies were previouslyfunded on an historical cost input basis. For 1996?97, payments were made accordingto the new Non-admitted Radiation Oncology Classification System and include fourkey components. Fixed grants are based on Weighted Radiation Therapy Servicestargets for megavoltage courses, planning procedures (dosimetry and simulation) andconsultations. The additional throughput pool covers additional Weighted RadiationTherapy Services once targets are reached, with access conditional on the utilisationof a minimum number of megavoltage fields by each hospital. Block grants coverspecialised treatments, such as brachytherapy, allied health payments and other supportservices. Compensation grants were available to bring payments up to the level of theprevious year. There is potential to provide incentives to promote best practice inAustralia through linking appropriate practice to funding models. Key Australian andinternational developments should be monitored, including economic evaluationstudies, classification and funding models, and the deliberations of the AmericanCollege of Radiology, the American Society for Therapeutic Radiology and Oncology,the Trans-Tasman Radiation Oncology Group and the Council of Oncology Societiesof Australia. National impact on clinical practice guidelines in Australia can beachieved through the Quality of Care and Health Outcomes Committee of theNational Health and Medical Research Council.
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McGrath, Pam, and Hamish Holewa. "End-of-life Care of Aboriginal Peoples in Remote Locations: Language Issues." Australian Journal of Primary Health 13, no. 1 (2007): 18. http://dx.doi.org/10.1071/py07003.
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To date, there is scant research literature that explores the provision of end-of-life care to Aboriginal peoples in Australia. In particular, there is a lack of published research available on issues at the interface of Aboriginal languages and English during palliative care. The complexity and importance of the issue for palliative care provision, however, is demonstrated by the fact that in Australia, Aboriginality is itself a very broad category, containing many distinct language groups and subcultures. Thus, although to date there is some mention of the problems associated with language in the literature, there is scant research on the topic of the provision of palliative care to Aboriginal peoples in remote areas. The following findings from a recent two-year National Health and Medical Research Council (NHMRC) study are provided to address this hiatus. The findings provide insights on the impact of language difference on palliative care practice for Aboriginal peoples in the Northern Territory of Australia.
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Pilowsky, I. "Australian Psychiatry and the Tradition of Aubrey Lewis. Edited by D. Copolov. (Pp. 70.) National Health and Medical Research Council, Schizophrenia Research Unit: Melbourne, Australia. 1991." Psychological Medicine 22, no. 4 (November 1992): 1063–64. http://dx.doi.org/10.1017/s0033291700038642.
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Thoumi, Andrew, Gerald B. Fogarty, Elizabeth J. Paton, and Stephen Shumack. "Is the contribution of Australian research to the national 2019 clinical practice guidelines for keratinocyte cancer adequate? A simple analysis." International Journal of Radiology & Radiation Therapy 8, no. 4 (October 12, 2021): 144–54. http://dx.doi.org/10.15406/ijrrt.2021.08.00307.
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Introduction: The Australian 2002 National Health and Medical Research Council (NHMRC) treatment guidelines for non-melanoma skin cancer (NMSC) were updated in 2008. At this time, the lack of high-quality Australian research conducted between 2002 to 2008 was noted. The primary aim of the present study was to assess the improvement in the quantity and quality of Australian research in the 2019 keratinocyte cancer guidelines. Secondary aims included an assessment of the quantity and quality of Australian research in comparison to the guidelines provided by the other selected countries, and an evaluation of the improvements in the Australian contribution since 2008. Method: Surgical (Sx) and radiotherapy (RT) treatment sections were interrogated. The analysis was simple. Each reference was counted as one unit. The quantity assessment was carried out by categorizing the references according to their country of origin: Australia, United Kingdom (UK), United States (US) and European Union (EU) countries, which were grouped as one country (EU) for the purpose of this study. The number of references from each country were then added up. To assess for quality, all references were ranked according to the American Society of Plastic Surgeons (ASPS) rating scale. A quality ratio for each country was then calculated by dividing the total number of prospective trials (i.e., levels I and II) by the number of retrospective studies (level III and lower) from each country if the numbers were sufficient. To evaluate the Australian improvement since 2008, Australian references were first categorized according to their year of publication (2002 to 2017), and then allocated to one of four bins of class intervals representing time periods. Results: Twenty-five of the 133 Sx references in the 2019 guidelines were Australian, which was less than the US (58) and EU (37), but better than the UK (12). Quality ratios were: Australia 0.8, UK 1.4, US 0.31, and EU 0.48. Of the 238 RT references, Australia contributed 53, US 107, EU 62, and UK 16. Quality ratios were: Australia 0.06, UK 0.3, US 0.18, and EU 0.34. Australia’s contribution to the UK and US RT guidelines were evaluated. For the UK RT guidelines (11 references), Australia contributed 3, UK 1, US 2 and EU 5. For the US ASTRO guidelines (101 references), Australia contributed 20, UK 1, US 44 and EU 36. Quality ratios were Australia 0.11, US 0.19 and EU 0.2. For Australian research overtime (2002-2017), the quantity and quality of Sx papers are decreasing; whereas for RT, the quantity is increasing but the quality remains poor. Conclusion: The contribution of Australian research to Australia’s own keratinocyte cancer guidelines is not the highest and did not improve over the period of evaluation. The same can be stated for Australia’s research contribution to the UK and US RT guidelines. Australia needs to do more high-quality research.
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Renzaho, Andre, Michael Polonsky, David Mellor, and Sheila Cyril. "Addressing migration-related social and health inequalities in Australia: call for research funding priorities to recognise the needs of migrant populations." Australian Health Review 40, no. 1 (2016): 3. http://dx.doi.org/10.1071/ah14132.
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Objective Migrants constitute 26% of the total Australian population and, although disproportionately affected by chronic diseases, they are under-represented in health research. The aim of the present study was to describe trends in Australian Research Council (ARC)- and National Health and Medical Research Council (NHMRC)-funded initiatives from 2002 to 2011 with a key focus on migration-related research funding. Methods Data on all NHMRC- and ARC-funded initiatives between 2002 and 2011 were collected from the research funding statistics and national competitive grants program data systems, respectively. The research funding expenditures within these two schemes were categorised into two major groups: (1) people focused (migrant-related and mainstream-related); and (2) basic science focused. Descriptive statistics were used to summarise the data and report the trends in NHMRC and ARC funding over the 10-year period. Results Over 10 years, the ARC funded 15 354 initiatives worth A$5.5 billion, with 897 (5.8%) people-focused projects funded, worth A$254.4 million. Migrant-related research constituted 7.8% of all people-focused research. The NHMRC funded 12 399 initiatives worth A$5.6 billion, with 447 (3.6%) people-focused projects funded, worth A$207.2 million. Migrant-related research accounted for 6.2% of all people-focused initiatives. Conclusions Although migrant groups are disproportionately affected by social and health inequalities, the findings of the present study show that migrant-related research is inadequately funded compared with mainstream-related research. Unless equitable research funding is achieved, it will be impossible to build a strong evidence base for planning effective measures to reduce these inequalities among migrants. What is known about the topic? Immigration is on the rise in most developing countries, including Australia, and most migrants come from low- and middle-income countries. In Australia, migrants constitute 26% of the total Australian population and include refugee and asylum seeker population groups. Migrants are disproportionately affected by disease, yet they have been found to be under-represented in health research and public health interventions. What does this paper add? This paper highlights the disproportions in research funding for research among migrants. Despite migrants being disproportionately affected by disease burden, research into their health conditions and risk factors is grossly underfunded compared with the mainstream population. What are the implications for practitioners? Migrants represent a significant proportion of the Australian population and hence are capable of incurring high costs to the Australian health system. There are two major implications for practitioners. First, the migrant population is constantly growing, therefore integrating the needs of migrants into the development of health policy is important in ensuring equity across health service delivery and utilisation in Australia. Second, the health needs of migrants will only be uncovered when a clear picture of their true health status and other determinants of health, such as psychological, economic, social and cultural, are identified through empirical research studies. Unless equitable research funding is achieved, it will be impossible to build a strong evidence base for planning effective measures to reduce health and social inequalities among migrant communities.
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Gillespie, Nathan A., Anjali K. Henders, Tracy A. Davenport, Daniel F. Hermens, Margie J. Wright, Nicholas G. Martin, and Ian B. Hickie. "The Brisbane Longitudinal Twin Study: Pathways to Cannabis Use, Abuse, and Dependence Project—Current Status, Preliminary Results, and Future Directions." Twin Research and Human Genetics 16, no. 1 (November 28, 2012): 21–33. http://dx.doi.org/10.1017/thg.2012.111.
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We describe the data being collected from the Brisbane Longitudinal Twin Study in Australia as part of the US National Institute on Drug Abuse (NIDA)-funded project, Pathways to Cannabis Use, Abuse and Dependence. The history, recruitment, assessment, and retention of twin families in this project are described in detail, along with preliminary findings and plans for future research. The goal of this NIDA project is to make a significant contribution to the discovery of quantitative trait loci influencing cannabis use disorders. Although the focus is cannabis use, abuse, and dependence in young adults, measures of comorbid illicit drug use disorders are also being collected. In addition, a variety of internalizing and externalizing disorders are being assessed, funded by support from the Australian National Health and Medical Research Council. Because these same twins have participated in numerous twin studies since 1992, future plans will include linking different phenotypes to investigate relationships between drug use, psychiatric disorders, and psychological phenotypes within cross-sectional and longitudinal or developmental frameworks.
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Carey, Marion. "What is the evidence for potential health impacts from wind power?" Proceedings of the Royal Society of Victoria 126, no. 2 (2014): 35. http://dx.doi.org/10.1071/rs14034.
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Wind power is a major renewable energy source without most of the environmental pollution associated with the fossil fuel industries. It therefore has great potential to protect and improve health through reducing ambient air pollution, maintaining healthy ecosystems and reducing the risks of climate change. Climate change is in itself a major threat to human health, so a rapid transition to renewable energy is vital. In recent years in Australia, however, anti-wind groups have claimed that wind turbines can cause a wide array of health impacts including ‘wind turbine syndrome’. These claims and anecdotal reports are commonly found on internet searches and reported in the media. The focus of these claims has been primarily on suggested impacts from low frequency sound, particularly infrasound1. The issue has become highly politicised, so separating out the facts from the hyperbole can be difficult. Despite arguments being played out in the media and in the courts, and an Australian Senate Inquiry, there is a paucity of high quality research in the peer-reviewed literature directly on the health impacts of wind turbines. Nevertheless, there is some published evidence, primarily relating to perception and impacts of noise, and what relevant scientific evidence exists has been extensively reviewed. Over a dozen reviews of the literature have been undertaken over the last decade internationally,3 and in Australia a review has been undertaken by both the National Health and Medical Research Council (NHMRC) and the Victorian Department of Health.
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Hancock, Andrew D., and David M. de Kretser. "The axonemal ultrastructure of spermatozoa from men with asthenospermia**Supported by a project grant from the National Health and Medical Research Council of Australia, Canberra, Australian Capital Territory, Australia." Fertility and Sterility 57, no. 3 (March 1992): 661–64. http://dx.doi.org/10.1016/s0015-0282(16)54917-6.
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Langhorne, Peter, Olivia Wu, Helen Rodgers, Ann Ashburn, and Julie Bernhardt. "A Very Early Rehabilitation Trial after stroke (AVERT): a Phase III, multicentre, randomised controlled trial." Health Technology Assessment 21, no. 54 (September 2017): 1–120. http://dx.doi.org/10.3310/hta21540.
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BackgroundMobilising patients early after stroke [early mobilisation (EM)] is thought to contribute to the beneficial effects of stroke unit care but it is poorly defined and lacks direct evidence of benefit.ObjectivesWe assessed the effectiveness of frequent higher dose very early mobilisation (VEM) after stroke.DesignWe conducted a parallel-group, single-blind, prospective randomised controlled trial with blinded end-point assessment using a web-based computer-generated stratified randomisation.SettingThe trial took place in 56 acute stroke units in five countries.ParticipantsWe included adult patients with a first or recurrent stroke who met physiological inclusion criteria.InterventionsPatients received either usual stroke unit care (UC) or UC plus VEM commencing within 24 hours of stroke.Main outcome measuresThe primary outcome was good recovery [modified Rankin scale (mRS) score of 0–2] 3 months after stroke. Secondary outcomes at 3 months were the mRS, time to achieve walking 50 m, serious adverse events, quality of life (QoL) and costs at 12 months. Tertiary outcomes included a dose–response analysis.Data sourcesPatients, outcome assessors and investigators involved in the trial were blinded to treatment allocation.ResultsWe recruited 2104 (UK,n = 610; Australasia,n = 1494) patients: 1054 allocated to VEM and 1050 to UC. Intervention protocol targets were achieved. Compared with UC, VEM patients mobilised 4.8 hours [95% confidence interval (CI) 4.1 to 5.7 hours;p < 0.0001] earlier, with an additional three (95% CI 3.0 to 3.5;p < 0.0001) mobilisation sessions per day. Fewer patients in the VEM group (n = 480, 46%) had a favourable outcome than in the UC group (n = 525, 50%) (adjusted odds ratio 0.73, 95% CI 0.59 to 0.90;p = 0.004). Results were consistent between Australasian and UK settings. There were no statistically significant differences in secondary outcomes at 3 months and QoL at 12 months. Dose–response analysis found a consistent pattern of an improved odds of efficacy and safety outcomes in association with increased daily frequency of out-of-bed sessions but a reduced odds with an increased amount of mobilisation (minutes per day).LimitationsUC clinicians started mobilisation earlier each year altering the context of the trial. Other potential confounding factors included staff patient interaction.ConclusionsPatients in the VEM group were mobilised earlier and with a higher dose of therapy than those in the UC group, which was already early. This VEM protocol was associated with reduced odds of favourable outcome at 3 months cautioning against very early high-dose mobilisation. At 12 months, health-related QoL was similar regardless of group. Shorter, more frequent mobilisation early after stroke may be associated with a more favourable outcome.Future workThese results informed a new trial proposal [A Very Early Rehabilitation Trial – DOSE (AVERT–DOSE)] aiming to determine the optimal frequency and dose of EM.Trial registrationThe trial is registered with the Australian New Zealand Clinical Trials Registry number ACTRN12606000185561, Current Controlled Trials ISRCTN98129255 and ISRCTN98129255.FundingThis project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme and will be published in full inHealth Technology Assessment; Vol. 21, No. 54. See the NIHR Journals Library website for further project information. Funding was also received from the National Health and Medical Research Council Australia, Singapore Health, Chest Heart and Stroke Scotland, Northern Ireland Chest Heart and Stroke, and the Stroke Association. In addition, National Health and Medical Research Council fellowship funding was provided to Julie Bernhardt (1058635), who also received fellowship funding from the Australia Research Council (0991086) and the National Heart Foundation (G04M1571). The Florey Institute of Neuroscience and Mental Health, which hosted the trial, acknowledges the support received from the Victorian Government via the Operational Infrastructure Support Scheme.
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Kennedy, Michelle, Amanual Getnet Mersha, Raglan Maddox, Catherine Chamberlain, Sian Maidment, Peter O'Mara, Cathy Segan, et al. "Koori Quit Pack mailout smoking cessation support for Aboriginal and Torres Strait Islander people who smoke: a feasibility study protocol." BMJ Open 12, no. 10 (October 2022): e065316. http://dx.doi.org/10.1136/bmjopen-2022-065316.
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IntroductionSmoking remains the leading preventable cause of death for Aboriginal and Torres Strait Islander people in Australia. Aboriginal and Torres Strait Islander people who smoke are more likely to make a quit attempt than their non-Aboriginal counterparts but less likely to sustain the quit attempt. There is little available evidence specifically for and by Indigenous peoples to inform best practice smoking cessation care.The provision of a free Koori Quit Pack with optional nicotine replacement therapy sent by mail may be a feasible, acceptable and effective way to access stop smoking support for Aboriginal and Torres Strait Islander peoples.Methods and analysisAn Aboriginal-led, multisite non-randomised single-group, pre–post feasibility study across three states in Australia will be conducted. Participants will be recruited via service-targeted social media advertising and during usual care at their Aboriginal Community Controlled Health Services. Through a process of self-referral, Aboriginal and Torres Strait Islander people who smoke daily will complete a survey and receive mailout smoking cessation support. Data will be collected over the phone by an Aboriginal Research Assistant. This pilot study will inform the development of a larger, powered trial.Ethics and disseminationEthics approval has been obtained from the Aboriginal Health & Medical Research Council Ethics Committee of New South Wales (NSW) (#1894/21) and the University of Newcastle (#H-2022-0174). Findings will be reported through peer-reviewed journals and presentations at relevant local, national and international conferences. The findings will be shared with the NSW and Victoria Quitline, Aboriginal Health and Medical Research Council and Victorian Aboriginal Community Controlled Organisation and the National Heart Foundation.Trial registration numberACTRN12622000654752.
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Teichtahl, Harry, Peter D. Temple-Smith, Jacqueline L. Johnson, Graeme J. Southwick, and David M. de Kretser. "Obstructive azoospermia and chronic sinobronchial disease (Young’s syndrome) in identical twins**Supported by the National Health and Medical Research Council of Australia." Fertility and Sterility 47, no. 5 (May 1987): 879–81. http://dx.doi.org/10.1016/s0015-0282(16)59186-9.
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Schofield, Deborah, Michelle M. Cunich, and Lucio Naccarella. "An evaluation of the quality of evidence underpinning diabetes management models: a review of the literature." Australian Health Review 38, no. 5 (2014): 495. http://dx.doi.org/10.1071/ah14018.
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Objective There is a paucity of research on the quality of evidence relating to primary care workforce models. Thus, the aim of the present study was to evaluate the quality of evidence on diabetes primary care workforce models in Australia. Methods The National Health and Medical Research Council of Australia’s (National Health and Medical Reseach Council; 2000, 2001) frameworks for evaluating scientific evidence and economic evaluations were used to assess the quality of studies involving primary care workforce models for diabetes care involving Australian adults. A search of medical databases (MEDLINE, AMED, RURAL, Australian Indigenous HealthInfoNet and The Cochrane Institute), journals for diabetes care (Diabetes Research and Clinical Practice, Diabetes Care, Diabetic Medicine, Population Health Management, Rural and Remote Health, Australian Journal of Primary Health, PLoS Medicine, Medical Journal of Australia, BMC Health Services Research, BMC Public Health, BMC Family Practice) and Commonwealth and state government health websites was undertaken to acquire Australian studies of diabetes workforce models published 2005–13. Various diabetes workforce models were examined, including ‘one-stop shops’, pharmacy care, Aboriginal services and telephone-delivered interventions. The quality of evidence was evaluated against several criteria, including relevance and replication, strength of evidence, effect size, transferability and representativeness, and value for money. Results Of the14 studies found, four were randomised controlled trials and one was a systematic review (i.e. Level II and I (best) evidence). Only three provided a replicable protocol or detailed intervention delivery. Eleven lacked a theoretical framework. Twelve reported significant improvements in clinical (patient) outcomes, commonly HbA1c, cholesterol and blood pressure; only four reported changes in short- and long-term outcomes (e.g. quality of life). Most studies used a small or targeted population. Only two studies assessed both benefits and costs of their intervention compared with usual care and cost effectiveness. Conclusions More rigorous studies of diabetes workforce models are needed to determine whether these interventions improve patient outcomes and, if they do, represent value for money. What is known about the topic? Although health systems with strong primary care orientations have been associated with enhanced access, equity and population health, the primary care workforce is facing several challenges. These include a mal-distribution of resources (supply side) and health outcomes (demand side), inconsistent support for teamwork care models, and a lack of enhanced clinical inter-professional education and/or training opportunities. These challenges are exacerbated by an ageing health workforce and general population, as well as a population that has increased prevalence of chronic conditions and multi-morbidity. Although several policy directions have been advocated to address these challenges, there is a lack of high-quality evidence about which primary care workforce models are best (and which models represent better value for money than current practice) and what the health effects are for patients. What does this paper add? This study demonstrated several strengths and weaknesses of Australian diabetes models of care studies. In particular, only five of the 14 studies assessed were designed in a way that enabled them to achieve a Level II or I rating (and hence the ‘best’ level of evidence), based on the NHMRC’s (2000, 2001) frameworks for assessing scientific evidence. The majority of studies risked the introduction of bias and thus may have incorrect conclusions. Only a few studies described clearly what the intervention and the comparator were and thus could be easily replicated. Only two studies included cost-effectiveness studies of their interventions compared with usual care. What are the implications for practitioners? Although there has been an increase in the number of primary care workforce models implemented in Australia, there is a need for more rigorous research to assess whether these interventions are effective in producing improved health outcomes and represent better value for money than current practice. Researchers and policymakers need to make decisions based on high-quality evidence; it is not obvious what effect the evidence is having on primary care workforce reform.
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Markus, JA, and AB Mcbratney. "An urban soil study: heavy metals in Glebe, Australia." Soil Research 34, no. 3 (1996): 453. http://dx.doi.org/10.1071/sr9960453.
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This study investigated the occurrence of Pb, Zn, Cu, and Cd in the topsoil of an inner-city suburb of Sydney, Australia. The total heavy metal concentrations in the topsoil of Glebe were determined along with their spatial distribution. These concentrations were compared with environmental investigation limits. Stratified random sampling was conducted within 1-ha square areas taking a samples at 1 m separation from each stratum as a means to investigating spatial variation. Total metal concentrations were determined on an aqua regia extract analysed using atomic absorption spectroscopy. Fifty percent of total Pb, Zn, and Cu concentrations and 2.5% of Cd concentrations were above the ANZECC and NH&MRC (Australia & New Zealand Environment Conservation Council and National Health & Medical Research Council) guidelines of 300, 200, 60, and 3 mg/kg, respectively. Some spatial clustering was evident and a geostatistical analysis showed some large high-risk areas. Fuzzy clustering showed 5 groups of increasing contamination. Soil disturbance and distance from road explained 24% of the variation in total Pb concentration, 15% in total Zn and Cu concentrations, and 13% in total Cd concentration.
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Hopper, John L., Debra L. Foley, Paul A. White, and Vincent Pollaers. "Australian Twin Registry: 30 Years of Progress." Twin Research and Human Genetics 16, no. 1 (December 3, 2012): 34–42. http://dx.doi.org/10.1017/thg.2012.121.
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The Australian Twin Registry (ATR) is a national volunteer resource of twin pairs and higher-order multiples willing to consider participating in health, medical, and scientific research. The vision of the ATR is ‘to realize the full potential of research involving twins to improve the health and well-being of all Australians’. The ATR has been funded continuously by the National Health and Medical Council for more than 30 years. Its core functions entail the recruitment and retention of twin members, the maintenance of an up-to-date database containing members’ contact details and baseline information, and the promotion and provision of open access to researchers from all institutes in Australia, and their collaborators, in a fair and equitable manner. The ATR is administered by The University of Melbourne, which acts as custodian. Since the late 1970s the ATR has enrolled more than 40,000 twin pairs of all zygosities and facilitated more than 500 studies that have produced at least 700 peer-reviewed publications from classical twin studies, co-twin control studies, within-pair comparisons, twin family studies, longitudinal twin studies, randomized controlled trials, and epigenetics studies, as well as studies of issues specific to twins. New initiatives include: a Health and Life Style Questionnaire; data collection, management, and archiving using a secure online software program (The Ark); and the International Network of Twin Registries. The ATR's expertise and 30 years of experience in providing services to national and international twin studies has made it an important resource for research across a broad range of disciplines.
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Norman, Robert J., Stacey Masters, and William Hague. "Hyperinsulinemia is common in family members of women with polycystic ovary syndrome**Supported by the National Health and Medical Research Council, Canberra, Australian Capital Territory, Australia." Fertility and Sterility 66, no. 6 (December 1996): 942–47. http://dx.doi.org/10.1016/s0015-0282(16)58687-7.
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Allman-Farinelli, Margaret, Annette Byron, Clare Collins, Janelle Gifford, and Peter Williams. "Challenges and lessons from systematic literature reviews for the Australian dietary guidelines." Australian Journal of Primary Health 20, no. 3 (2014): 236. http://dx.doi.org/10.1071/py13016.
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In 2009–10 the Dietitians Association of Australia conducted a series of systematic reviews for the National Health and Medical Research Council to generate evidence statements to inform the revision of the Dietary Guidelines for Australians. In total 202 body of evidence statements were constructed and assigned a grading detailing the certainty with which each could be used to inform policy. This paper describes some of the challenges and insights gained from the process, specifically related to: study type, study quality assessment, the lack of quantified data, diet exposure, definition of a healthy population, generalisability and applicability, and resource allocation. It is clear that there is still a need for further refinement of the methods for evaluating evidence for nutrition policy, but the current dietary guidelines are now much more robustly evidence informed than ever before.
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Gallo, Linda, Karen Moritz, and Lisa Akison. "Nutrient Intake, Physical Activity Levels, and Metabolic Status in Australian University Biomedical Students." Current Developments in Nutrition 4, Supplement_2 (May 29, 2020): 1404. http://dx.doi.org/10.1093/cdn/nzaa061_032.
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Abstract Objectives This study aimed to assess nutritional intake, physical activity levels and their association to metabolic health in a cohort of university biomedical science students. Methods This study followed a cross-sectional design. Participants were recruited from a third-year endocrinology practical class from The University of Queensland (2018–2019), with complete data obtained from 324 students, aged 19–25 years (n = 196 females and 128 males of which 57% were Caucasian, 28% Asian, 7% Subcontinental Asian, 6% of mixed race or other, and 2% not disclosed). Nutritional intake was quantified using the Automated 24 h dietary assessment Tool (ASA24-Australia) and physical activity levels quantified using the Active Australia Survey. Results Mean height and body mass (±SD) was 164.36 cm (±6.85) and 60.0 kg (±10.6) in females and 178.1 cm (±7.41) and 73.4 kg (±11.5) in males. Median daily energy intake was 6760 kJ in females and 10,338 kJ in males. The following nutrients had a low percentage of female and/or male students meeting the minimum recommendations: fibre (24% of females and 30% of males), calcium (16% of females and 32% of males), folate (32% of females, 59% of males), iron (6% of females, 80% of males), and potassium (33% of females and 32% of males). In females, median daily intake was well below recommendations for calcium (621 vs 1000 mg) and iron (8.8 vs 18 mg). Sufficient level of physical activity, defined as at least 150 minutes over at least five sessions in one week, was met in 82% of females and 85% of males. Conclusions These results suggest that undergraduate biomedical science students in Australia have inadequate intakes of fibre, calcium, folate, and potassium, with a particular concern regarding the very low intake of calcium and iron among young adult females. Associations to metabolic health, including blood glucose control, insulin sensitivity, advanced glycation end products, and body composition are currently being analysed. Funding Sources The study was funded by institutional support from School of Biomedical Sciences, The University of Queensland, Australia. L.A.G. was supported by an Early Career Fellowship from the National Health and Medical Research Council and Heart Foundation (Australia), and a UQ Amplify Fellowship. K.M.M was supported by a Senior Research Fellowship from the National Health and Medical Research Council.
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Marklund, Matti, Miaobing Zheng, J. Lennert Veerman, and Jason H. Y. Wu. "Estimated Health Benefits, Costs, and Cost-Effectiveness of Eliminating Industrial Trans-Fatty acids in Australia." Current Developments in Nutrition 4, Supplement_2 (May 29, 2020): 1720. http://dx.doi.org/10.1093/cdn/nzaa064_010.
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Abstract Objectives To assess the potential cost-effectiveness, health gains, and effects on health equality of eliminating industrial trans-fatty acids (TFAs) from the Australian food supply. Methods Markov cohort models were used to estimate the cost-effectiveness and policy impact on (ischemic heart disease) IHD burden and health equity of a national ban of industrial TFAs in Australia. Intake of TFA was assessed using the 2011–2012 Australian National Nutrition and Physical Activity Survey. The IHD burden attributable to TFA was calculated by comparing the current level of TFA intake to a counterfactual setting (0.5% energy per day from TFA; corresponding to TFA intake only from non-industrial sources, e.g., dairy foods). Policy costs, avoided IHD events and deaths, health-adjusted life years (HALYs) gained, and IHD-related healthcare costs saved were estimated over 10 years and lifetime of the adult Australian population. Cost-effectiveness was assessed by calculation of incremental cost-effectiveness ratios (ICER) using net policy cost and HALYs gained. Health benefits and health care cost changes were also assessed in subgroups based on socioeconomic status and remoteness. Results Elimination of industrial TFA was estimated to prevent 2,294 (95% uncertainty interval [UI]: 1,765; 2,851) IHD deaths and 9,931 (95% UI: 8,429; 11,532) IHD events over the first 10 years. The greatest health benefits were accrued to the most socioeconomically disadvantaged quintiles and among Australians living outside of major cities. The intervention was estimated to be cost-saving or cost-effective (i.e., ICER < 169,361 AUD/HALY) regardless of the time horizon, with ICERs of 1,073 (95% UI: dominant; 3,503) and 1,956 (95% UI: 1,010; 2,750) AUD/HALY over 10 years and life time, respectively. The TFA ban was estimated to be cost-saving or highly cost-effective in sensitivity analyses altering assumptions of post-intervention TFA intake, abundance of TFA-containing products, or discount rate. Conclusions A ban of industrial TFAs could avert substantial numbers of IHD events and deaths in Australia and will likely be a highly cost-effective strategy to reduce social-economic and urban-rural inequalities in health. Funding Sources National Health and Medical Research Council; and UNSW.
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Rathore, Vatsna, Amy E. Mitchell, Alina Morawska, and Santosh Kumar Tadakamadla. "Online Parenting Intervention for Children’s Eating and Mealtime Behaviors: Protocol of a Randomized Controlled Trial." Healthcare 10, no. 5 (May 17, 2022): 924. http://dx.doi.org/10.3390/healthcare10050924.
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Introduction: Obesity and overweight are significant health problems among Australian children. Parents play a vital role in establishing healthy eating behaviors in their children. However, parents often experience difficulties in implementing effective parenting practices and lack confidence in their ability to help children adopt these behaviors. This trial will evaluate the efficacy of an online program, Healthy Habits Triple P, in improving children’s snacking and mealtime behaviors and related parenting practices. Methods and analysis: This is a single-blinded, randomized controlled trial for parents of young Australian children aged 2–6 years. Participants will be recruited through childcare centers, social media, online parent forums and existing networks. The participants in the intervention arm will receive access to a web-based parenting intervention in addition to nutrition-related information for parents published by the National Health and Medical Research Council of Australia; those in the control arm will receive nutrition-related information only. After the completion of the study, the parenting intervention will be offered to the control arm. The primary outcome will be improvement in children’s eating habits. The secondary outcomes include parents’ self-efficacy, confidence, children’s mealtime behaviors and mealtime parenting strategies. Both primary and secondary outcomes will be evaluated through online-administered, validated parent-reported questionnaires. We will also undertake a quantitative and qualitative evaluation of the practicality and acceptability of the intervention.
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Tuffaha, Haitham W., Najwan El Saifi, Suzanne K. Chambers, and Paul A. Scuffham. "Directing research funds to the right research projects: a review of criteria used by research organisations in Australia in prioritising health research projects for funding." BMJ Open 8, no. 12 (December 2018): e026207. http://dx.doi.org/10.1136/bmjopen-2018-026207.
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ObjectivesHealthcare budgets are limited, and therefore, research funds should be wisely allocated to ensure high-quality, useful and cost-effective research. We aimed to critically review the criteria considered by major Australian organisations in prioritising and selecting health research projects for funding.MethodsWe reviewed all grant schemes listed on the Australian Competitive Grants Register that were health-related, active in 2017 and with publicly available selection criteria on the funders’ websites. Data extracted included scheme name, funding organisation, selection criteria and the relative weight assigned to each criterion. Selection criteria were grouped into five representative domains: relevance, appropriateness, significance, feasibility (including team quality) and cost-effectiveness (ie, value for money).ResultsThirty-six schemes were included from 158 identified. One-half of the schemes were under the National Health and Medical Research Council. The most commonly used criteria were research team quality and capability (94%), research plan clarity (94%), scientific quality (92%) and research impact (92%). Criteria considered less commonly were existing knowledge (22%), fostering collaboration (22%), research environment (19%), value for money (14%), disease burden (8%) and ethical/moral considerations (3%). In terms of representative domains, relevance was considered in 72% of the schemes, appropriateness in 92%, significance in 94%, feasibility in 100% and cost-effectiveness in 17%. The relative weights for the selection criteria varied across schemes with 5%–30% for relevance, 20%–60% for each appropriateness and significance, 20%–75% for feasibility and 15%–33% for cost-effectiveness.ConclusionsIn selecting research projects for funding, Australian research organisations focus largely on research appropriateness, significance and feasibility; however, value for money is most often overlooked. Research funding decisions should include an assessment of value for money in order to maximise return on research investment.
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Hopper, John L., Susan A. Treloar, Nicholas H. de Klerk, and Ruth Morley. "Australian Twin Registry: A Nationally Funded Resource for Medical and Scientific Research, Incorporating match and WATCH." Twin Research and Human Genetics 9, no. 6 (December 1, 2006): 707–11. http://dx.doi.org/10.1375/twin.9.6.707.
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AbstractThe Australian Twin Registry (ATR) has, since the late 1970s, enrolled more than 30,000 pairs of all zygosity types and ages willing to consider participation in approved research studies. Its core functions are the recruitment to, and maintenance of, an up-to-date database containing contact details and baseline information, and the management of fair and equitable access so as to enhance medical and scientific research. The ATR has facilitated more than 430 studies producing 525 peer-reviewed publications using a variety of designs including classic biometrical twin and twin family studies, co-twin control studies, intervention studies, longitudinal studies, and studies of issues relevant specifically to twins. The ATR is supported for 2004 to 2009 by an Australian National Health and Medical Research Council (NHMRC) Enabling Grant, a new form of funding which recognizes the importance of long-term support for shared national resources. New initiatives include: integration with the Western Australian Twin Child Health (WATCH) cohort and the new Western Australian Twin Registry (WATR); foundation of a cohort of mothers and their twin children recruited from the time of diagnosis of the multiple gestation (match); a national Twins Festival run in collaboration with the Australian Multiple Birth Association (AMBA); promotion of the ATR at medical conferences; and fostering an active network of researchers from a range of disciplines and providing financial support for new researchers to attend international twin research workshops. Consistent with its mission statement, the long-term goal of the ATR is to make twin studies a standard component of medical and scientific research.
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Doran, Christopher M., Rod Ling, Andrew Searles, and Peter Hill. "Does evidence influence policy? Resource allocation and the Indigenous Burden of Disease study." Australian Health Review 40, no. 6 (2016): 705. http://dx.doi.org/10.1071/ah15105.
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Objective The Indigenous Burden of Disease (IBoD) report is the most comprehensive assessment of Indigenous disease burden in Australia. The aim of the present study was to investigate the potential effect of the IBoD report on Australian Indigenous health policy, service expenditure and research funding. Findings have significance for understanding factors that may influence Indigenous health policy. Methods The potential effect of the IBoD report was considered by: (1) conducting a text search of pertinent documents published by the federal government, Council of Australian Governments and the National Health and Medical Research Council of Australia (NHMRC) and observing the quantity and quality of references to IBoD; (2) examining data on government Indigenous healthcare expenditure for trends consistent with the findings and policy implications of the IBoD report; and (3) examining NHMRC Indigenous grant allocation trends consistent with the findings and policy implications of the IBoD report. Results Of 110 government and NHMRC documents found, IBoD was cited in 27. Immediately after publication of the IBoD report, federal and state governments increased Indigenous health spending (relative to non-Indigenous), notably for community health and public health at the state level. Expenditure on Indigenous hospital separations for chronic diseases also increased. These changes are broadly consistent with the findings of the IBoD report on the significance of chronic disease and the need to address certain risk factors. However, there is no evidence that such changes had a causal connection with the IBoD study. After publication of the IBoD report, changes in NHMRC Indigenous research funding showed little consistency with the findings of the IBoD report. Conclusions The present study found only indirect and inconsistent correlational evidence of the potential influence of the IBoD report on Indigenous health expenditure and research funding. Further assessment of the potential influence of the IBoD report on Indigenous health policy will require more targeted research, including interviews with key informants involved in developing health policy. What is known about the topic? There are currently no publications that consider the potential effed of the IBoD study on Indigenous health expenditure and research funding. What does this paper add? This paper offers the first consideration of the potential effect of the IBoD report. It contains analyses of data from readily available sources, examining national expenditures on Indigenous health and NHMRC Indigenous research, before and after the publication of the IBoD report. What are the implications for practitioners? The paper is relevant to analysts interested in drivers of Indigenous health policy. Although it finds correlations between the release of the IBoD report and some subsequent health spending decisions, other factors should be investigated to better understand the complexity of processes that drive government efforts to improve Indigenous health.
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Markus, JA, and AB Mcbratney. "Corrigendum — An urban soil study: heavy metals in Glebe, Australia." Soil Research 34, no. 3 (1996): 466. http://dx.doi.org/10.1071/sr9960453c.
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This study investigated the occurrence of Pb, Zn, Cu, and Cd in the topsoil of an inner-city suburb of Sydney, Australia. The total heavy metal concentrations in the topsoil of Glebe were determined along with their spatial distribution. These concentrations were compared with environmental investigation limits. Stratified random sampling was conducted within 1-ha square areas taking 2 samples at 1 m separation from each stratum as a means to investigating spatial variation. Total metal concentrations were determined on an aqua regia extract analysed using atomic absorption spectroscopy. Fifty percent of total Pb, Zn, and Cu concentrations and 2.5% of Cd concentrations were above the ANZECC and NH&MRC (Australia & New Zealand Environment Conservation Council and National Health & Medical Research Council) guidelines of 300, 200, 60, and 3 mg/kg, respectively. Some spatial clustering was evident and a geostatistical analysis showed some large high-risk areas. Fuzzy clustering showed 5 groups of increasing contamination. Soil disturbance and distance from road explained 24% of the variation in total Pb concentration, 15% in total Zn and Cu concentrations, and 13% in total Cd concentration.
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Whop, Lisa J., Tamara L. Butler, Julia M. L. Brotherton, Kate Anderson, Joan Cunningham, Allison Tong, and Gail Garvey. "Study protocol: Yarning about HPV Vaccination: a qualitative study of factors influencing HPV vaccination among Aboriginal and Torres Strait Islander adolescents in Australia." BMJ Open 11, no. 8 (August 2021): e047890. http://dx.doi.org/10.1136/bmjopen-2020-047890.
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IntroductionAboriginal and Torres Strait Islander women experience a higher burden of cervical cancer than non-Indigenous women in Australia. Cervical cancer is preventable partly through human papillomavirus (HPV) vaccination; in Australia, this is delivered through the national school-based immunisation programme. While HPV vaccination uptake is high among Australian adolescents, there remain gaps in uptake and completion among Aboriginal and Torres Strait Islander adolescents. This study aims to gain a comprehensive understanding of the barriers and facilitators to HPV vaccination uptake and completion among Aboriginal and Torres Strait Islander adolescents in Queensland, Australia.Methods and analysisThe study will be guided by an Indigenist research approach and an ecological model for health promotion. Yarning, a qualitative Indigenous research method, will be conducted in up to 10 schools. Participants will include Year 7 (12/13 years old) Aboriginal and Torres Strait Islander adolescents; parents/caregivers; and local key informants and immunisation programme partners involved in the delivery of school-based HPV immunisation programme. Participants will be recruited through school representatives and investigator networks using purposive and snowball sampling and samples of convenience. Field notes, HPV vaccination clinic observations and sequential diagramming of the HPV vaccination process will be conducted. Thematic analysis of data will be led by Aboriginal and Torres Strait Islander researchers. Synthesised sequential diagrams of the process of HPV vaccination and qualitative themes summarising key findings will be produced.Ethics and disseminationThe Aboriginal Health and Medical Research Council of New South Wales Ethics Committee (1646/20), the Australian National University Human Research Ethics Committee (HREC, 2020/478), the HREC of the Northern Territory Department of Health and Menzies School of Health Research (19-3484) and the Townsville Hospital and Health Service HREC (HREC/QTHS/73789) have approved the study. Dissemination will occur via conferences and peer-reviewed publications. Further dissemination will be determined in partnership with the Aboriginal and Torres Strait Islander Steering Committee, including Youth Representatives and Consultation Network.
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Lai, Chi-Wan. "Experiences of Accreditation of Medical Education in Taiwan." Journal of Educational Evaluation for Health Professions 6 (December 20, 2009): 2. http://dx.doi.org/10.3352/jeehp.2009.6.2.
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This review aims to introduce the Taiwanese Medical Accreditation System: its history, role and future goals. In 1999, the Ministry of Education, Taiwanese Government commissioned the non-profit National Health Research Institutes (NHRI) to develop a new medical accreditation system. According to that policy, the Taiwan Medical Accreditation Council (TMAC) was established in the same year. The council serves a similar function to that of the Liaison Committee on Medical Education (LCME) of the United States and the Australian Medical Council (AMC). The accreditation process consists of a self-assessment plus a four-day site visit by a team of eight medical educators that are headed by one of the council members of the TMAC. The first cycle of initial visits was completed from 2001 to 2004. Subsequent follow-up visits were arranged according to the results of the survey with smaller-sized teams and shorter periods. There is evidence to suggest that the majority (seven of eleven) of the medical schools in Taiwan have made good progress. TMAC?占퐏 next step will be to monitor the progress and raise the standard of medical education in individual schools with a homogenous, superior standard of medical education.
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Yuen, Joshua, Antony Clark, Jonathon Q. Ng, Nigel Morlet, Jill Keeffe, Hugh R. Taylor, and David B. Preen. "Further survey of Australian ophthalmologist's diabetic retinopathy management: did practice adhere to National Health and Medical Research Council guidelines?" Clinical & Experimental Ophthalmology 38, no. 6 (May 10, 2010): 613–19. http://dx.doi.org/10.1111/j.1442-9071.2010.02326.x.
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Goyen, Judith. "Learning Difficulties in Children and Adolescents National Health and Medical Research Council (1990). Canberra: Australian Government Publishing Service (30pp.)." Australasian Journal of Special Education 16, no. 2 (1992): 49. http://dx.doi.org/10.1017/s1030011200024015.
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Perez Chacon, Gladymar, Marie J. Estcourt, James Totterdell, Dianne E. Campbell, Kirsten P. Perrett, Julie A. Marsh, Peter C. Richmond, et al. "OPTIMUM study protocol: an adaptive randomised controlled trial of a mixed whole-cell/acellular pertussis vaccine schedule." BMJ Open 10, no. 12 (December 2020): e042838. http://dx.doi.org/10.1136/bmjopen-2020-042838.
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IntroductionCombination vaccines containing whole-cell pertussis antigens were phased out from the Australian national immunisation programme between 1997 and 1999 and replaced by the less reactogenic acellular pertussis (aP) antigens. In a large case–control study of Australian children born during the transition period, those with allergist diagnosed IgE-mediated food allergy were less likely to have received whole-cell vaccine in early infancy than matched population controls (OR: 0.77 (95% CI, 0.62 to 0.95)). We hypothesise that a single dose of whole-cell vaccine in early infancy is protective against IgE-mediated food allergy.Methods and analysisThis adaptive double-blind randomised controlled trial is investigating whether a mixed whole-cell/aP vaccine schedule prevents allergic disease in the first year of life. The primary outcome is IgE-mediated food allergy by 12 months of age. Secondary outcomes include new onset of atopic dermatitis by 6 or 12 months of age; sensitisation to at least one allergen by 12 months of age; seroconversion in anti-pertussis toxin IgG titres after vaccination with aP booster at 18 months of age; and solicited systemic and local adverse events following immunisation with pertussis-containing vaccines. Analyses will be performed using a Bayesian group sequential design.Ethics and disseminationThis study has been approved by the Child and Adolescent Health Service Human Research Ethics Committee, Perth, Western Australia (RGS 00019). The investigators will ensure that this trial is conducted in accordance with the principles of the Declaration of Helsinki and with the International Conference on Harmonisation Guidelines for Good Clinical Practice. Individual consent will be requested. Parents will be reimbursed reasonable travel and parking costs to attend the study visits. The dissemination of these research findings will follow the National Health and Medical Research Council of Australia Open Access Policy.Trial registration numberACTRN12617000065392p.
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Giles, Glenn, Merridy Malin, and Peter Harvey. "The Centre of Clinical Research Excellence in Aboriginal and Torres Strait Islander Health: An Operational Rationale and Some Reflections on Progress so far." Australian Journal of Primary Health 12, no. 2 (2006): 97. http://dx.doi.org/10.1071/py06028.
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The Centre of Clinical Research Excellence (CCRE) in Aboriginal and Torres Strait Islander Health was established in late 2003 through a major National Health and Medical Research Council (NHMRC) grant involving collaboration between the Aboriginal Health Council of South Australia (AHCSA), Flinders University, and Aboriginal Health Services. Our foundation research communities are the Aboriginal communities served by these Aboriginal Health Services in the Spencer Gulf / Eyre Peninsula region. In recent years a number of collaborative research programs involving chronic illness management, self-management and coordinated care have been implemented in these communities and this work is the basis of the initial CCRE activities. Key objectives of the CCRE are to improve the health status of Indigenous people through conducting relevant and meaningful Aboriginal controlled health research, providing formal training for Indigenous health researchers and developing innovative approaches to health care that can be readily translated and applied to support communities. The inclusion, empowerment and engagement of Indigenous people in the process of managing community health represent tangible strategies for achieving more equitable health outcomes for Aboriginal people. This paper outlines the CCRE operational rationale and presents early activities and outcomes across the three strategic areas of CCRE operations: research, education and training, and translation. Some critical reflections are offered on the progress and experience of the CCRE thus far. A common obstacle this CCRE has encountered is that the limited (especially staff) resources available to the Aboriginal Health Services with which we are collaborating make it difficult for them to engage with and progress the projects we are pursuing.
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Harrison, Kristie H., KS Kylie Lee, Timothy Dobbins, Scott Wilson, Noel Hayman, Rowena Ivers, Paul S. Haber, et al. "Supporting Aboriginal Community Controlled Health Services to deliver alcohol care: protocol for a cluster randomised controlled trial." BMJ Open 9, no. 11 (November 2019): e030909. http://dx.doi.org/10.1136/bmjopen-2019-030909.
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IntroductionIndigenous peoples who have experienced colonisation or oppression can have a higher prevalence of alcohol-related harms. In Australia, Aboriginal Community Controlled Health Services (ACCHSs) offer culturally accessible care to Aboriginal and Torres Strait Islander (Indigenous) peoples. However there are many competing health, socioeconomic and cultural client needs.Methods and analysisA randomised cluster wait-control trial will test the effectiveness of a model of tailored and collaborative support for ACCHSs in increasing use of alcohol screening (with Alcohol Use Disorders Identification Test-Consumption (AUDIT-C)) and of treatment provision (brief intervention, counselling or relapse prevention medicines).SettingTwenty-two ACCHSs across Australia.RandomisationServices will be stratified by remoteness, then randomised into two groups. Half receive support soon after the trial starts (intervention or ‘early support’); half receive support 2 years later (wait-control or ‘late support’).The supportCore support elements will be tailored to local needs and include: support to nominate two staff as champions for increasing alcohol care; a national training workshop and bimonthly teleconferences for service champions to share knowledge; onsite training, and bimonthly feedback on routinely collected data on screening and treatment provision.Outcomes and analysisPrimary outcome is use of screening using AUDIT-C as routinely recorded on practice software. Secondary outcomes are recording of brief intervention, counselling, relapse prevention medicines; and blood pressure, gamma glutamyltransferase and HbA1c. Multi-level logistic regression will be used to test the effectiveness of support.Ethics and disseminationEthical approval has been obtained from eight ethics committees: the Aboriginal Health and Medical Research Council of New South Wales (1217/16); Central Australian Human Research Ethics Committee (CA-17-2842); Northern Territory Department of Health and Menzies School of Health Research (2017-2737); Central Queensland Hospital and Health Service (17/QCQ/9); Far North Queensland (17/QCH/45-1143); Aboriginal Health Research Ethics Committee, South Australia (04-16-694); St Vincent’s Hospital (Melbourne) Human Research Ethics Committee (LRR 036/17); and Western Australian Aboriginal Health Ethics Committee (779).Trial registration numberACTRN12618001892202; Pre-results.
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Zion, Deborah, and Richard Matthews. "Can research ethics codes be a conduit for justice? An examination of Aboriginal and Torres Strait Islander guidelines in Australia." Research Ethics 18, no. 1 (October 25, 2021): 51–63. http://dx.doi.org/10.1177/17470161211053199.
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Aboriginal and Torres Strait Islander peoples in Australia, have historically experienced research as another means of colonialization and oppression. Although there are existing frameworks, guidelines and policies in place that respond to this history, the risk of exploitation and oppression arising from research still raises challenging ethical questions. Since the 1990s the National Health and Medical Research Council in Australia has developed specific sets of guidelines that govern research with these populations in an attempt to redress injustices of the past. The current guidelines: Ethical Conduct in Research with Aboriginal and Torres Strait Islander Peoples and Communities: Guidelines for Researchers and Stakeholders, 2018, emphasis six core values which are bound together by “spirit and integrity.” The values are reflected through respect for cultural inheritance, and genuine negotiation of partnerships between researchers, other stakeholders, and communities. We examine whether these guidelines can lead to research and research practices that redress some of the ongoing traumas of colonialization and racism. We draw upon Margaret Urban Walker’s formulation of restorative justice, based upon her “pragmatics of repair” which relies upon “voice, validation and vindication” and at its core, the restoration of relationships.
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Gete, Dereje, Michael Waller, and Gita Mishra. "The Role of Child Diets in the Association between Pre-pregnancy Diets and Childhood Behavioral Problems: A Mediation Analysis." Current Developments in Nutrition 6, Supplement_1 (June 2022): 902. http://dx.doi.org/10.1093/cdn/nzac067.022.
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Abstract Objectives To quantify the mediating role of childhood diets in the association between maternal diets before pregnancy and offspring behavioral problems. Methods This study included 1448 mother-child pairs from the Australian longitudinal study on women's health and its sub-study mothers and their children's health. The healthy eating index score was constructed using a semi-quantitative and validated 101-item food-frequency questionnaire. Childhood behavioral problems were assessed using the strengths and difficulties questionnaire. Three dietary patterns were identified using principal component analysis to explore childhood dietary patterns (high fats and sugar; prudent diets; and diary). A causal inference framework for mediation analysis was used to quantify the mediating role of childhood diets in the association between pre-pregnancy diets and the risk of offspring behavioral problems. Results We found a 20% of the total effect of the poor adherence to pre-pregnancy diet quality on the risk of offspring behavioral problems was mediated through childhood high consumptions of fats and sugar. No clear mediating effect through prudent, and diary childhood diets was observed. Conclusions This study suggests that childhood high fats and sugar consumption may contribute to the total effects of the pre-pregnancy diets on the risk of childhood behavioral problems. Funding Sources The ALSWH is funded by the Australian Government Department of Health. MatCH is funded by the National Health and Medical Research Council (NHMRC) project grant. Dereje Gete is supported by the University of Queensland Research Training Scholarship. Gita Mishra holds the Australian Health and Medical Research Council Principal Research Fellowship.
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St John, Winsome, Heather James, and Shona McKenzie. "Health Service Provision for Community-Dwelling People Suffering Urinary Incontinence: A Case Study of Neglect." Australian Journal of Primary Health 7, no. 3 (2001): 31. http://dx.doi.org/10.1071/py01043.
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Access to health services for common health problems is a fundamental principle of primary health care. Although there have been few Australian prevalence studies, it is estimated that about 900,000 adult Australians suffer from incontinence (National Health and Medical Research Council, 1994). The purpose of this study was to investigate urinary continence services for community-dwelling people in the Gold Coast region of Australia, prior to implementing new services. A case study design was used, including: a survey of general medical practitioners, specialist medical practitioners, physiotherapists, hospitals, and home visiting agencies in the region; a focus group with key stakeholders; and a critical review of the literature in relation to prevalence, treatment-seeking behaviour and service provision. Health practitioners were asked about services provided, policies, clinical pathways, referrals, and their views on what services they would like to see offered in the region. Results showed that while there were some existing continence-specific services in the region, they were inadequate to provide for the numbers of people in need. Many generalist health practitioners demonstrated a lack of interest in and knowledge of the plight of those suffering from incontinence. Links between services were found to be ad hoc, with inconsistent referral patterns between health professionals. These findings are consistent with international studies. It was concluded that, in general, community-dwelling people suffering incontinence were poorly served by health professionals due an inability of available services to meet demand, and a lack of knowledge and/or interest by many generalist health practitioners.
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Duncan, Bob. "Men and Mental HealthA.F. Jorm (Editor) National Health and Medical Research Council Canberra: Australian Government Publishing Service (1995) 163pp: $16.95." Behaviour Change 12, no. 4 (December 1995): 246–47. http://dx.doi.org/10.1017/s0813483900004204.
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Walker, Ruth, Danielle Mazza, Michelle Blumfield, Christie Bennett, and Helen Truby. "Maternal gestational weight gain during pregnancy: prioritising the conversation." Australian Journal of Primary Health 24, no. 1 (2018): 4. http://dx.doi.org/10.1071/py17111.
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Pregnancy is a critical stage of life requiring urgent attention when taking a lifespan approach to obesity prevention. Excessive gestational weight gain (GWG) is highly predictive of overweight and obesity later in life for women and their offspring. This discussion describes the challenges faced by health professionals (general practitioners, midwives, allied health) in primary care in Australia when addressing GWG, presents evidence that supports re-prioritising GWG and highlights strategies that can be used to address GWG. The revised National Health and Medical Research Council antenatal care guidelines (to be formally released in early 2018) indicate it will be the responsibility of health professionals in antenatal care to initiate conversations about GWG with women. Women are open to discussing this sensitive topic and health professionals in primary care have an opportunity to be proactive in addressing barriers that have hindered conversations about GWG in the past so that women are supported to manage their weight during pregnancy.
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Hayward, Christopher S., Wally V. Kalnins, Peter Rogers, Michael P. Feneley, Peter S. Macdonald, and Raymond P. Kelly. "Effect of Inhaled Nitric Oxide on Normal Human Left Ventricular Function fn1fn1Dr. Hayward is a recipient of a Postgraduate Medical Research Scholarship from the National Health and Medical Research Council of Australia, Canberra, Australia. This work was supported by a Research Project Grant to Dr. Kelly from the National Heart Foundation of Australia, Canberra, Australia." Journal of the American College of Cardiology 30, no. 1 (July 1997): 49–56. http://dx.doi.org/10.1016/s0735-1097(97)00143-5.
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