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Journal articles on the topic 'Nanofibrous materials'

Author: Grafiati

Published: 28 June 2021

Last updated: 1 February 2022

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1

Zhong, Wen, Malcolm M. Q. Xing, and Howard I. Maibach. "Nanofibrous materials for wound care." Cutaneous and Ocular Toxicology 29, no. 3 (June 2, 2010): 143–52. http://dx.doi.org/10.3109/15569527.2010.489307.

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2

Burger, Christian, Benjamin S. Hsiao, and Benjamin Chu. "NANOFIBROUS MATERIALS AND THEIR APPLICATIONS." Annual Review of Materials Research 36, no. 1 (August 2006): 333–68. http://dx.doi.org/10.1146/annurev.matsci.36.011205.123537.

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3

GÜLER, BUKET, and FUNDA CENGİZ ÇALLIOĞLU. "Comparative analysis of superabsorbent properties of PVP and PAA nanofibres." Industria Textila 72, no. 04 (September 1, 2021): 460–66. http://dx.doi.org/10.35530/it.072.04.1806.

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This study presents the comparative analysis of production, characterization and absorption properties of Polyvinylpyrrolidone (PVP) and Polyacrylic acid (PAA) nanofibres. Firstly, optimization studies about polymer (PVP and PAA), superabsorbent additive (waterlock)(WL) and crosslinker agent (sodium persulfate and glutaraldehyde)concentrations were achieved. Then solution properties such as conductivity, surface tension and viscosity were determined. Electrospinning was carried out under the optimum process parameters (voltage, distance between the electrodes, solution feed rate etc.) to obtain superabsorbent nanofibrous surfaces. Surface and fibre morphologies were analysed with Scanning Electron Microscopy (SEM) and thickness of nanoweb and weight in grams of nanofibres were also measured. Lastly, optimized PVP and PAA nanofibres were compared in terms of absorption properties with water and synthetic urine with various times from 5 to 86400 seconds. According to the results, generally fine, smooth and uniform nanofibres were obtained. It was observed that the solution viscosity, conductivity, and average fibre diameter increase with waterlock (WL) and cross-linker additions while surface tension was not change. In addition, PAA nanofibres’ absorption capacity with water and synthetic urine was higher than PVP nanofibres, while PVP nanofibres’ absorption rate is higher. It is possible to say that electrospun nanofibrous surfaces that are ultra-thin, light, porous and with high specific surface area to volume ratio are promising for new superabsorbent materials.

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4

Ungur, Ganna. "Nanofibrous Filtering Materials With Catalytic Activity." Advanced Materials Letters 5, no. 8 (August 1, 2014): 422–28. http://dx.doi.org/10.5185/amlett.2014.amwc1025.

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5

Dong, Yuping, Yuqi Zheng, Keyan Zhang, Yueming Yao, Lihuan Wang, Xiaoran Li, Jianyong Yu, and Bin Ding. "Electrospun Nanofibrous Materials for Wound Healing." Advanced Fiber Materials 2, no. 4 (March 21, 2020): 212–27. http://dx.doi.org/10.1007/s42765-020-00034-y.

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6

Sinha, M. K., B. R. Das, D. Bharathi, N. E. Prasad, B. Kishore, P. Raj, and K. Kumar. "Electrospun Nanofibrous Materials for Biomedical Textiles." Materials Today: Proceedings 21 (2020): 1818–26. http://dx.doi.org/10.1016/j.matpr.2020.01.236.

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7

Zhou, Shufei, and Wen Zhong. "Adhesion and Binding in Nanofibrous Materials." Journal of Adhesion Science and Technology 24, no. 1 (January 2010): 35–44. http://dx.doi.org/10.1163/016942409x12538865055953.

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8

Zhang, Zhanpeng, and Peter X. Ma. "From Nanofibrous Hollow Microspheres to Nanofibrous Hollow Discs and Nanofibrous Shells." Macromolecular Rapid Communications 36, no. 19 (August 6, 2015): 1735–41. http://dx.doi.org/10.1002/marc.201500342.

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9

Venugopal, J., Molamma P. Prabhakaran, Yanzhong Zhang, Sharon Low, Aw Tar Choon, and S. Ramakrishna. "Biomimetic hydroxyapatite-containing composite nanofibrous substrates for bone tissue engineering." Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 368, no. 1917 (April 28, 2010): 2065–81. http://dx.doi.org/10.1098/rsta.2010.0012.

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The fracture of bones and large bone defects owing to various traumas or natural ageing is a typical type of tissue malfunction. Surgical treatment frequently requires implantation of a temporary or permanent prosthesis, which is still a challenge for orthopaedic surgeons, especially in the case of large bone defects. Mimicking nanotopography of natural extracellular matrix (ECM) is advantageous for the successful regeneration of damaged tissues or organs. Electrospun nanofibre-based synthetic and natural polymer scaffolds are being explored as a scaffold similar to natural ECM for tissue engineering applications. Nanostructured materials are smaller in size falling, in the 1–100 nm range, and have specific properties and functions related to the size of the natural materials (e.g. hydroxyapatite (HA)). The development of nanofibres with nano-HA has enhanced the scope of fabricating scaffolds to mimic the architecture of natural bone tissue. Nanofibrous substrates supporting adhesion, proliferation, differentiation of cells and HA induce the cells to secrete ECM for mineralization to form bone in bone tissue engineering. Our laboratory (NUSNNI, NUS) has been fabricating a variety of synthetic and natural polymer-based nanofibrous substrates and synthesizing HA for blending and spraying on nanofibres for generating artificial ECM for bone tissue regeneration. The present review is intended to direct the reader’s attention to the important subjects of synthetic and natural polymers with HA for bone tissue engineering.

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10

Yousefzadeh, Maryam, Masoud Latifi, Mohammad Amani-Tehran, Wee-Eong Teo, and Seeram Ramakrishna. "A Note on the 3D Structural Design of Electrospun Nanofibers." Journal of Engineered Fibers and Fabrics 7, no. 2 (June 2012): 155892501200700. http://dx.doi.org/10.1177/155892501200700204.

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In this paper, various three-dimensional (3D) nanofibrous structures were constructed based on liquid support systems and alteration of the solution charge property. Structures fabricated from the liquid support system include a nanofibrous ring and spindle-shaped nanofibrous ones. The ease of fabricating fluffy, randomly organized nanofibrous structure by altering the charge capacity of the electrospun solution is also demonstrated. The set-up conditions for the design of the nanofibrous structures using these techniques are discussed.

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11

Magiera, Anna, Jarosław Markowski, Elzbieta Menaszek, Jan Pilch, and Stanislaw Blazewicz. "PLA-Based Hybrid and Composite Electrospun Fibrous Scaffolds as Potential Materials for Tissue Engineering." Journal of Nanomaterials 2017 (2017): 1–11. http://dx.doi.org/10.1155/2017/9246802.

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The aim of the study was to manufacture poly(lactic acid)- (PLA-) based nanofibrous nonwovens that were modified using two types of modifiers, namely, gelatin- (GEL-) based nanofibres and carbon nanotubes (CNT). Hybrid nonwovens consisting of PLA and GEL nanofibres (PLA/GEL), as well as CNT-modified PLA nanofibres with GEL nanofibres (PLA + CNT/GEL), in the form of mats, were manufactured using concurrent-electrospinning technique (co-ES). The ability of such hybrid structures as potential scaffolds for tissue engineering was studied. Both types of hybrid samples and one-component PLA and CNTs-modified PLA mats were investigated using scanning electron microscopy (SEM), water contact angle measurements, and biological and mechanical tests. The morphology, microstructure, and selected properties of the materials were analyzed. Biocompatibility and bioactivity in contact with normal human osteoblasts (NHOst) were studied. The coelectrospun PLA and GEL nanofibres retained their structures in hybrid samples. Both types of hybrid nonwovens were not cytotoxic and showed better osteoinductivity in comparison to scaffolds made from pure PLA. These samples also showed significantly reduced hydrophobicity compared to one-component PLA nonwovens. The CNT-contained PLA nanofibres improved mechanical properties of hybrid samples and such a 3D system appears to be interesting for potential application as a tissue engineering scaffold.

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12

Mao, Xue, Ying Bai, Jianyong Yu, and Bin Ding. "Insights into the flexibility of ZrMxOy (M = Na, Mg, Al) nanofibrous membranes as promising infrared stealth materials." Dalton Transactions 45, no. 15 (2016): 6660–66. http://dx.doi.org/10.1039/c6dt00319b.

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An undersized dopant dependent brittle to flexible transition in ZrM_xO_y (M = Na, Mg, Al) nanofibrous membranes was revealed. Al doped zirconia nanofibrous membranes with an ultra-flexibility of 23 mN exhibit low infrared emissivity.

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13

Kopeć, Kamil, Michał Wojasiński, and Tomasz Ciach. "Superhydrophilic Polyurethane/Polydopamine Nanofibrous Materials Enhancing Cell Adhesion for Application in Tissue Engineering." International Journal of Molecular Sciences 21, no. 18 (September 16, 2020): 6798. http://dx.doi.org/10.3390/ijms21186798.

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The use of nanofibrous materials in the field of tissue engineering requires a fast, efficient, scalable production method and excellent wettability of the obtained materials, leading to enhanced cell adhesion. We proposed the production method of superhydrophilic nanofibrous materials in a two-step process. The process is designed to increase the wettability of resulting scaffolds and to enhance the rate of fibroblast cell adhesion. Polyurethane (PU) nanofibrous material was produced in the solution blow spinning process. Then the PU fibers surface was modified by dopamine polymerization in water solution. Two variants of the modification were examined: dopamine polymerization under atmospheric oxygen (V-I) and using sodium periodate as an oxidative agent (V-II). Hydrophobic PU materials after the treatment became highly hydrophilic, regardless of the modification variant. This effect originates from polydopamine (PDA) coating properties and nanoscale surface structures. The modification improved the mechanical properties of the materials. Materials obtained in the V-II process exhibit superior properties over those from the V-I, and require shorter modification time (less than 30 min). Modifications significantly improved fibroblasts adhesion. The cells spread after 2 h on both PDA-modified PU nanofibrous materials, which was not observed for unmodified PU. Proposed technology could be beneficial in applications like scaffolds for tissue engineering.

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14

Tsai, Shiao-Wen, Chun-Chiang Huang, Lih-Rou Rau, and Fu-Yin Hsu. "Fabrication of Aligned Carbon Nanotube/Polycaprolactone/Gelatin Nanofibrous Matrices for Schwann Cell Immobilization." Journal of Nanomaterials 2014 (2014): 1–8. http://dx.doi.org/10.1155/2014/498131.

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In this study, we utilized a mandrel rotating collector consisting of two parallel, electrically conductive pieces of tape to fabricate aligned electrospun polycaprolactone/gelatin (PG) and carbon nanotube/polycaprolactone/gelatin (PGC) nanofibrous matrices. Furthermore, we examined the biological performance of the PGC nanofibrous and film matrices using anin vitroculture of RT4-D6P2T rat Schwann cells. Using cell adhesion tests, we found that carbon nanotube inhibited Schwann cell attachment on PGC nanofibrous and film matrices. However, the proliferation rates of Schwann cells were higher when they were immobilized on PGC nanofibrous matrices compared to PGC film matrices. Using western blot analysis, we found that NRG1 and P0 protein expression levels were higher for cells immobilized on PGC nanofibrous matrices compared to PG nanofibrous matrices. However, the carbon nanotube inhibited NRG1 and P0 protein expression in cells immobilized on PGC film matrices. Moreover, the NRG1 and P0 protein expression levels were higher for cells immobilized on PGC nanofibrous matrices compared to PGC film matrices. We found that the matrix topography and composition influenced Schwann cell behavior.

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15

Balakrishnan, Suganya Bharathi, Manawwer Alam, Naushad Ahmad, Manikandan Govindasamy, Sakthivelu Kuppu, and Stalin Thambusamy. "Electrospinning nanofibrous graft preparation and wound healing studies using ZnO nanoparticles and glucosamine loaded with poly(methyl methacrylate)/polyethylene glycol." New Journal of Chemistry 45, no. 18 (2021): 7987–98. http://dx.doi.org/10.1039/d0nj05409g.

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As wound dressing materials, electrospun nanofibrous scaffolds have a lot of promise. Electrospun nanofibrous scaffolds in combination with ZnO nanoparticles have antimicrobial and antioxidant properties, making electrospinning a successful technique for wound dressings.

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16

Lee, Yee-Shuan, and Treena Livingston Arinzeh. "Electrospun Nanofibrous Materials for Neural Tissue Engineering." Polymers 3, no. 1 (February 9, 2011): 413–26. http://dx.doi.org/10.3390/polym3010413.

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17

MATSUMOTO, HIDETOSHI. "Endeavors towards Function Exploration of Nanofibrous Materials." Sen'i Gakkaishi 74, no. 1 (2018): P—39—P—43. http://dx.doi.org/10.2115/fiber.74.p-39.

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18

Kalinova, Klara. "Sound absorptive light comprising nanofibrous resonant membrane applicable in room acoustics." Building Services Engineering Research and Technology 39, no. 3 (September 29, 2017): 362–70. http://dx.doi.org/10.1177/0143624417733404.

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Room acoustic solutions are based on measurements of the acoustic power of the room and acoustic elements with different functions (absorption tiles, absorption ceilings, absorption bodies, diffusers, barriers). This work is focused only on absorption elements with an emphasis on addressing lower-middle frequencies. The design of the material is based on broad band noise. Damping of lower frequencies is restricted to a certain extent by the final thickness of the acoustic material. Nanofibrous resonant membranes will be used in the design to achieve higher sound absorption at lower frequencies in comparison with commercially available materials. The principle of the acoustic system is to use combination of a perforated sheet covered by a nanofibrous resonant membrane, which is brought into forced vibration upon impact of sound waves of low frequency. Practical application:To absorb sounds of high frequencies, porous materials are used. To absorb sounds of low frequencies, resonant membranes are employed. However, these structures absorb only sounds of certain frequency. Nanofibrous layers have unique acoustic properties due to the large specific surface area of the nanofibres, where viscous losses may occur, and also the ability to resonate at its own frequency. The advantage of this technology is the space between the acoustic element with a thickness of 1–2 mm and the wall/ceiling, which can be used for the installation of lighting/audio speakers, etc. The acoustic light prototype has been made.

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19

Ramamoorthy, Rajalakshmi, Muthumanickkam Andiappan, and Murugesan Muthalagu. "Characterization of polyherbal-incorporated polycaprolactone nanofibrous mat for biomedical applications." Journal of Bioactive and Compatible Polymers 34, no. 4-5 (July 2019): 401–11. http://dx.doi.org/10.1177/0883911519876065.

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The polyherbal-loaded polycaprolactone nanofibrous mat was prepared by electrospinning technique, and physical and chemical characteristics of nanofibrous mats were studied using scanning electron microscopy, x-ray diffraction, thermogravimetric analyzer, and Fourier transform infrared spectroscopy. The presence of various phytochemicals in the crude monoherbal and polyherbal extracts was analyzed. The antimicrobial activity and biocompatibility of the polyherbal-loaded nanofibrous mats were studied. The drug release pattern of the polyherbal-loaded nanofibrous mats was studied at different time intervals. The 5% drug-loaded nanofibrous mat shows higher sustainable drug release rate than 1% and 3% drug-loaded nanofibrous mats. The cell viability was found to be 98.91%, 98.77%, 98.5%, and 98.22% for polycaprolactone and 1%, 3%, and 5% for polyherbal-loaded nanofibrous mats, respectively.

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20

Ding, Fuyuan, Hongbing Deng, Yumin Du, Xiaowen Shi, and Qun Wang. "Emerging chitin and chitosan nanofibrous materials for biomedical applications." Nanoscale 6, no. 16 (2014): 9477–93. http://dx.doi.org/10.1039/c4nr02814g.

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21

Yong, Hsin Nam Ernest, Kim Yeow Tshai, and Siew Shee Lim. "Aqueous Stability of Cross-Linked Thermal Responsive Tissue Engineering Scaffold Produced by Electrospinning Technique." Key Engineering Materials 897 (August 17, 2021): 39–44. http://dx.doi.org/10.4028/www.scientific.net/kem.897.39.

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Poly (N-isopropylacrylamide) (PNIPAm) has been one of the most widely studied thermal responsive polymer in tissue engineering owing to its reversible hydrophilic-hydrophobic phase transition across its lower critical solution temperature (~32°C) that is close to human physiological temperatures. Among tissue engineering constructs, nanofibrous scaffolds offer an added advantage in mimicking the morphology of the native extracellular matrix (ECM). Electrospinning has been reported as one of the most facile method to produce PNIPAm nanofibres and neat electrospun nanofibres scaffold is known to possess poor aqueous stability, limiting its use in tissue engineering applications. In contrast, numerous studies on PNIPAm hydrogels have shown relatively good aqueous stability owing to the hydrophilic 3D crosslinked structure of the hydrogel which resist instant dissolution but rather swell to a greater or lesser extent. However, the presence of crosslinkages in PNIPAm hydrogels causes it to be hardly electrospinnable into nanofibres. In the present work, crosslinker free PNIPAm was radical polymerized to a high molecular weight of 385 kDa. To produce nanofibers, electrospinning was carried out on a dedicated %wt of PNIPAm solution containing octaglycidyl polyhedral oligomeric silsesquioxane (OpePOSS) and 2-ethyl-4-methylimidazole (EMI). Resulting PNIPAm nanofibrous network was found to strongly resemble the ECM morphology with fiber diameter of 436.35 ± 187.04 nm, pore size 1.24 ± 1.27 μm and 63.6% total porosity. Aqueous stability was studied in cell culture media over the course of 28 days. The current result shows significant improvement with a gradual mass loss up to a maximum of 35% instead of the near immediate dissolution observed in the case of electrospun neat PNIPAm scaffold without crosslinks.

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Vyslouzilova, Lucie, Martin Seidl, Jakub Hruza, Jiri Bobek, David Lukas, and Petr Lenfeld. "Nanofibrous Filters for Respirators." Advanced Materials Research 1119 (July 2015): 126–31. http://dx.doi.org/10.4028/www.scientific.net/amr.1119.126.

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This article deals with a development of new filtration materials for respirators. Contemporary used filters with charged microfibers are not sufficiently stable in all conditions and not efficient for all types of particles and that is the reason why the requirement for new generation of filtration materials is rising up. The research was focused on the development of nanofibrous filters that have a great precondition to be used as filters for respirators. The filtering material was designed as a multilayer sandwich consisting of spundbound, meltblown and nanofibrous layers. For the evaluation of final properties and filtering performances different 3D structures were also created.

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23

Liu, Xia, Adham Ahmed, Zhenxin Wang, and Haifei Zhang. "Nanofibrous microspheres via emulsion gelation and carbonization." Chemical Communications 51, no. 94 (2015): 16864–67. http://dx.doi.org/10.1039/c5cc07535a.

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Nanofibrous hydrogel microspheres are formed by pH gelation in emulsion droplets, which can then be freeze-dried and carbonized to produce nanofibrous carbon microspheres, showing high performance as electrode materials for supercapacitors.

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24

Qian, Yong Fang, Lai Jiu Zheng, Ruo Yuan Song, and Bing Du. "Electrospinning of Pullulan Nanofibers for Food Package Materials." Advanced Materials Research 821-822 (September 2013): 1321–25. http://dx.doi.org/10.4028/www.scientific.net/amr.821-822.1321.

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Electrospinning is a process that fabricates continuous fibers with diameters in the nanoto micron range. Pullulan with different concentrations were successfully electrospun into nanofibers with water as solvent in this study. We have evaluated the effects of solution concentration on the morphology of the fibers. The morphologies of the nanofibrous mats were examined by Scanning Electron Microscopy (SEM). With increasing the solution concentration, the electrospun nanofibers changed from beaded nanofibers to smooth nanofibers, meanwhile, the average diameters of electrospun pullulan nanofibers increased from 44nm, 89nm, 136nm, 172nm to 219nm when the solution concentration changed from 12, 15, 20, 25 to 30 wt%. The distribution of electrospun fibers is normal distribution. The electrospun nanofibrous mats will be a promising food package material.

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Daelemans, Lode, Iline Steyaert, Ella Schoolaert, Camille Goudenhooft, Hubert Rahier, and Karen De Clerck. "Nanostructured Hydrogels by Blend Electrospinning of Polycaprolactone/Gelatin Nanofibers." Nanomaterials 8, no. 7 (July 20, 2018): 551. http://dx.doi.org/10.3390/nano8070551.

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Nanofibrous membranes based on polycaprolactone (PCL) have a large potential for use in biomedical applications but are limited by the hydrophobicity of PCL. Blend electrospinning of PCL with other biomedical suited materials, such as gelatin (Gt) allows for the design of better and new materials. This study investigates the possibility of blend electrospinning PCL/Gt nanofibrous membranes which can be used to design a range of novel materials better suited for biomedical applications. The electrospinnability and stability of PCL/Gt blend nanofibers from a non-toxic acid solvent system are investigated. The solvent system developed in this work allows good electrospinnable emulsions for the whole PCL/Gt composition range. Uniform bead-free nanofibers can easily be produced, and the resulting fiber diameter can be tuned by altering the total polymer concentration. Addition of small amounts of water stabilizes the electrospinning emulsions, allowing the electrospinning of large and homogeneous nanofibrous structures over a prolonged period. The resulting blend nanofibrous membranes are analyzed for their composition, morphology, and homogeneity. Cold-gelling experiments on these novel membranes show the possibility of obtaining water-stable PCL/Gt nanofibrous membranes, as well as nanostructured hydrogels reinforced with nanofibers. Both material classes provide a high potential for designing new material applications.

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Llusar, Mario, and Clément Sanchez. "Inorganic and Hybrid Nanofibrous Materials Templated with Organogelators†." Chemistry of Materials 20, no. 3 (February 2008): 782–820. http://dx.doi.org/10.1021/cm702141e.

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Carrera, Diego, Fabio Manganini, Giacomo Boracchi, and Ettore Lanzarone. "Defect Detection in SEM Images of Nanofibrous Materials." IEEE Transactions on Industrial Informatics 13, no. 2 (April 2017): 551–61. http://dx.doi.org/10.1109/tii.2016.2641472.

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Jahan, Kazi I., Alexander Goponenko, and Yuris Dzenis. "Electrospun Nanofibrous Materials as Stimuli-Responsive Polymerized Hydrogels." Macromolecular Symposia 365, no. 1 (July 2016): 118–27. http://dx.doi.org/10.1002/masy.201650027.

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Sinha, Mukesh Kumar, and Biswa Ranjan Das. "Chitosan nanofibrous materials for chemical and biological protection." Journal of Textiles and Fibrous Materials 1 (January 1, 2018): 251522111878837. http://dx.doi.org/10.1177/2515221118788370.

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Chitosan derivatives are difficult to electrospun because they have poor flexibility of their polyelectrolyte chains. Based on extensive trails, we have successfully electrospun chitosan polymer and, subsequently, coated on non-woven polypropylene utilizing Nanospider technology. This experimentally developed nanofibrous webs of various densities were coated on non-woven fabric and, subsequently, stitched with activated carbon sphere (ACS) adhered composite fabric. Biological filtration and chemical protection were evaluated and the optimized density offering the highest value with meeting specified comfort was assessed. Results showed that optimized web morphology of 0.43 g m−2 is the best for integration with nuclear, biological and chemical absorbent layer of low ACS add-on in all aspects of comfort and protective behaviours. This will be meeting stringent defence protective requirements and lowering down the weight of suit by approximately 25%. An attempt has also been made in this research to protect from sulphur mustard chemical warfare agent by using both theories: (a) barrier techniques and (b) disintegrating the trapped molecules via functionalization of the web. Result shows that first molecules get trapped by in web layer (barrier effect) and subsequently destroyed by hydrolysis mechanism. Scanning microscopic image shows web is acting as barrier layer by trapping sulphur mustard particles. Optimized web of 0.43 g m−2 was functionalized with zinc (Zn) oxide and the presence of Zn particles was confirmed by imaging techniques. Crystalline and thermal analysis depicts that structural changes were found in sulphur mustard spotted functionalized web. Raman spectra show chemically disintegrated hydrolysed products of sulphur mustard. Bacterial filtration efficiency, antimicrobial and comfort properties were measured for assessing the introduction of nanowebs for biological protection and chemical protection in newly created multilayered fabric structure with low ACS add-on (180 g m−2). The initial encouraging outcome of this research expects whether the multilayered fabric could be introduced in the suit.

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Li, Xiao-Tao, Yan Zhang, and Guo-Qiang Chen. "Nanofibrous polyhydroxyalkanoate matrices as cell growth supporting materials." Biomaterials 29, no. 27 (September 2008): 3720–28. http://dx.doi.org/10.1016/j.biomaterials.2008.06.004.

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Zheng, Wenfu, Wei Zhang, and Xingyu Jiang. "Biomimetic Collagen Nanofibrous Materials for Bone Tissue Engineering." Advanced Engineering Materials 12, no. 9 (September 2010): B451—B466. http://dx.doi.org/10.1002/adem.200980087.

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Zhu, Jingxian, Xin Zhang, Zhenxing Shao, Linghui Dai, La Li, Xiaoqing Hu, Xiaokun Wang, Chunyan Zhou, and Yingfang Ao. "In VivoStudy of Ligament-Bone Healing after Anterior Cruciate Ligament Reconstruction Using Autologous Tendons with Mesenchymal Stem Cells Affinity Peptide Conjugated Electrospun Nanofibrous Scaffold." Journal of Nanomaterials 2013 (2013): 1–11. http://dx.doi.org/10.1155/2013/831873.

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Electrospinning nanofibrous scaffold was commonly used in tissue regeneration recently. Nanofibers with specific topological characteristics were reported to be able to induce osteogenic differentiation of MSCs. In thisin vivostudy, autologous tendon grafts with lattice-like nanofibrous scaffold wrapping at two ends of autologous tendon were used to promote early stage of ligament-bone healing after rabbit ACL reconstruction. To utilize native MSCs from bone marrow, an MSCs specific affinity peptide E7 was conjugated to nanofibrous meshes. After 3 months, H-E assessment and specific staining of collagen type I, II, and III showed direct ligament-bone insertion with typical four zones (bone, calcified fibrocartilage, fibrocartilage, and ligament) in bioactive scaffold reconstruction group. Diameters of bone tunnel were smaller in nanofibrous scaffold conjugated E7 peptide group than those in control group. The failure load of substitution complex also indicated a stronger ligament-bone insertion healing using bioactive scaffold. In conclusion, lattice-like nanofibrous scaffold with specific MSCs affinity peptide has great potential in promoting early stage of ligament-bone healing after ACL reconstruction.

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Ko, Sung Won, Ji Yeon Lee, Joshua Lee, Byeong Cheol Son, Se Rim Jang, Ludwig Erik Aguilar, Young Min Oh, Chan Hee Park, and Cheol Sang Kim. "Analysis of Drug Release Behavior Utilizing the Swelling Characteristics of Cellulosic Nanofibers." Polymers 11, no. 9 (August 21, 2019): 1376. http://dx.doi.org/10.3390/polym11091376.

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It is known that the behavior of a drug released from a supporting carrier is influenced by the surrounding environment and the carrier. In this study, we investigated the drug behavior of a swellable electrospun nanofibrous membrane. Nanofibrous mats with different swelling ratios were prepared by mixing cellulose acetate (CA) and polyurethane (PU). CA has excellent biocompatibility and is capable of high water uptake, while PU has excellent mechanical properties. Paclitaxel (PTX) was the drug of choice for observing drug release behavior, which was characterized by UV-spectroscopy. FE-SEM was used to confirm the morphology of the nanofibrous mats and to measure the average fiber diameters. We observed a noticeable increase in the total volume of the nanofibrous membrane when it was immersed in water. Also, the drug release behavior increased proportionally with increasing swelling rate of the composite nanofibrous mat. Biocompatibility testing of nanofiber materials was confirmed by CCK-8 assay and cell morphology was observed. Based on these results, we propose nanofibrous mats as promising candidates in wound dressing and other drug carrier applications.

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Zheng, Fuyin, Shige Wang, Wenxiu Hou, Yunchao Xiao, Pengchao Liu, Xiangyang Shi, and Mingwu Shen. "Comparative study of resazurin reduction and MTT assays for cytocompatibility evaluation of nanofibrous materials." Analytical Methods 11, no. 4 (2019): 483–89. http://dx.doi.org/10.1039/c8ay02310g.

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You, Yaying, Feng Chen, Junchao Qian, Qianyu Yan, and Zhigang Chen. "Nonhazardous Electrospun Biopolymer Nanofibrous Membrane for Antibacterial Filter." Nano 15, no. 07 (July 2020): 2050085. http://dx.doi.org/10.1142/s179329202050085x.

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Respiratory disease caused by the presence of bacteria in the atmosphere seriously threatens human health. Air pollution as harmful suspended particles, like haze, is conducive to bacterial spread and growth; it must be prevented to avoid harming the respiratory tract. Herein, filtration membranes possessing superior antibacterial activity are considered as an effective means to protect humans from atmospheres contaminated with bacteria. The aim of this study is to prepare an environmentally friendly and biodegradable multifunctional biopolymer composite nanofibrous membrane, which can be used as a candidate material for air filtration applications. Since traditional air filtration materials do not degrade in the natural environment, we synthesized a nanofibrous membrane composed of gelatin (GT) and silk fibroin (SF), in which antibacterial agent can anchor via electrostatic spinning. Also, both GT and SF can break down in the natural environment, which avoids secondary pollution of the atmosphere. Preliminary experiments show that GS nanofibrous membranes are excellent carriers of antibacterial agent for antibacterial applications. Several characterizations and testing measurements indicate that resultant nanofibrous membranes are effective against Gram-positive and Gram-negative bacteria. Moreover, a water vapor transmission rate test shows the excellent filtration performance of the materials.

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Fras Zemljič, Lidija, Uroš Maver, Tjaša Kraševac Glaser, Urban Bren, Maša Knez Hrnčič, Gabrijela Petek, and Zdenka Peršin. "Electrospun Composite Nanofibrous Materials Based on (Poly)-Phenol-Polysaccharide Formulations for Potential Wound Treatment." Materials 13, no. 11 (June 9, 2020): 2631. http://dx.doi.org/10.3390/ma13112631.

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In this paper, we focus on the preparation of electrospun composite nanofibrous materials based on (poly)-phenol-polysaccharide formulation. The prepared composite nanofibres are ideally suited as a controlled drug delivery system, especially for local treatment of different wounds, owing to their high surface and volume porosity and small fibre diameter. To evaluate the formulations, catechin and resveratrol were used as antioxidants. Both substances were embedded into chitosan particles, and further subjected to electrospinning. Formulations were characterized by determination of the particle size, encapsulation efficiency, as well as antioxidant and antimicrobial properties. The electrospinning process was optimised through fine-tuning of the electrospinning solution and the electrospinning parameters. Scanning electron microscopy was used to evaluate the (nano)fibrous structure, while the successful incorporation of bio substances was assessed by X-ray Photoelectron Spectroscopy and Fourier transform infrared spectroscopy. The bioactive properties of the formed nanofibre -mats were evaluated by measuring the antioxidative efficiency and antimicrobial properties, followed by in vitro substance release tests. The prepared materials are bioactive, have antimicrobial and antioxidative properties and at the same time allow the release of the incorporated substances, which assures a promising use in medical applications, especially in wound care.

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Dou, Hao, Kun-Bin Kuang, Yun-Yu Li, Wei Fan, Yue Shen, Hong-Yan Liu, and Ji-Huan He. "Effect of solution concentrations on the structure and properties of nanofibrous yarns by blown bubble-spinning." Thermal Science 25, no. 3 Part B (2021): 2155–60. http://dx.doi.org/10.2298/tsci200301101d.

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Solution properties play a critical role in manufacturing of nanofibrous materials. In this paper, solution concentrations were explored for the effective fabrication of nanofibrous yarns by the blown bubble-spinning. The surface tension and rheological property of spun solutions were investigated, and the product?s thermal and mechanical properties were characterized.

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Milašius, Rimvydas, Dzmitry Ryklin, Natallia Yasinskaya, Aliaksandr Yeutushenka, Audrone Ragaišiene, Žaneta Rukuižiene, and Daiva Mikučioniené. "Development of an Electrospun Nanofibrous Web with Hyaluronic Acid." Fibres and Textiles in Eastern Europe 25 (October 31, 2017): 8–12. http://dx.doi.org/10.5604/01.3001.0010.4620.

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Textile materials with an electrospun nanofibrous web can be used fo ar wide range of applications, including medicine and health care. In this research, polyamide-6 and hyaluronic acid were used for the development of a nanofibrous web via electrospinning. Hyaluronic acid is one of the most interesting ingredients used in skin care. It is very important that the electrospun polyamide-6 nanofibrous structure binds nanoparticles of hyaluronic acid not covering the surface of these particles. The main goal of this work was to develop an electrospun nanofibrous polyamide-6 web with hyaluronic acid which can be used for health care and/or cosmetology A. polyamide-6 nanofibrous web with hyaluronic acid was successfully developed via electrospinning. The presence of hyaluronic acid in the nanoweb was confirmed after web treatment with hot (95%) water. Hyaluronic acid was transported from the spinning solution to the electrospun web, was not isolated from the environment by polyamide-6, and could interact with human skin.

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Locilento, Danilo A., Luiza A. Mercante, Rafaela S. Andre, Luiz H. C. Mattoso, Genoveva L. F. Luna, Patricia Brassolatti, Fernanda de F. Anibal, and Daniel S. Correa. "Biocompatible and Biodegradable Electrospun Nanofibrous Membranes Loaded with Grape Seed Extract for Wound Dressing Application." Journal of Nanomaterials 2019 (March 6, 2019): 1–11. http://dx.doi.org/10.1155/2019/2472964.

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The development of nanofibrous membranes with tunable wettability, degradation, and biocompatibility is highly keen for biomedical applications, including drug delivery and wound dressing. In this study, biocompatible and biodegradable nanofibrous membranes with antioxidant properties were successfully prepared by the electrospinning technique. The membranes were developed using polylactic acid (PLA) and polyethylene oxide (PEO) as the matrix, with the addition of grape seed extract (GSE), a rich source of natural antioxidants. The nanofibrous membranes were thoroughly characterized both from the materials and from the biocompatibility point of view. PLA and PLA/PEO nanofibers showed high encapsulation efficiency, close to 90%, while the encapsulated GSE retained its antioxidant capacity in the membranes. In vitro release studies showed that GSE diffuses from PLA/GSE and PLA/PEO/GSE membranes in a Fickian diffusion manner, whose experimental data were well fitted using the Korsmeyer-Peppas model. Furthermore, a higher controlled release of GSE was observed for the PLA/PEO/GSE membrane. Moreover, culturing experiments with human foreskin fibroblast (HFF1) cells demonstrated that all samples are biocompatible and showed that the GSE-loaded PLA/PEO nanofibrous membranes support better cell attachment and proliferation compared to the PLA/GSE nanofibrous membranes, owing to the superior hydrophilicity. In summary, the results suggested that the GSE-loaded membranes are a promising topical drug delivery system and have a great potential for wound dressing applications.

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Lee, Ji Yeon, Deockhee Yoon, Byeong Cheol Son, Abdelrahman I. Rezk, Chan Hee Park, and Cheol Sang Kim. "Antimicrobial Electrospun Nanofibrous Mat Based on Essential Oils for Biomedical Applications." Journal of Nanoscience and Nanotechnology 20, no. 9 (September 1, 2020): 5376–80. http://dx.doi.org/10.1166/jnn.2020.17669.

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Polyurethane (PU) nanofibers containing three different essential oils (teatree, cinnamon bark, clove) were produced by electrospinning method. Morphology of the electrospun nanofibrous was studied using Field Emission Scanning Electron Microscope (FE-SEM). We were studying to reveal that different concentration of essential oil display different mechanical properties for the nanofibrous mat. The antibacterial properties of the nanofibrous loaded with the essential oil were studied quantitatively and qualitatively using three strains (Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa). The antibacterial evaluation showed higher antibacterial activity for nanofibrous loaded with essential oil compares to control sample. In vitro cell culture were proceed to confirm biocompatibility of the nanofibrous contained essential oils. In this study, we present a comparison of the samples for each of the experiment based on the derived test items and test methods. The results of this study demonstrate that the proposed nanofibrous mat loaded with essential oil will be a promising future material for different biomedical applications.

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Li, Zhen, Shunqi Mei, Yajie Dong, Fenghua She, Yongzhen Li, Puwang Li, and Lingxue Kong. "Functional Nanofibrous Biomaterials of Tailored Structures for Drug Delivery—A Critical Review." Pharmaceutics 12, no. 6 (June 8, 2020): 522. http://dx.doi.org/10.3390/pharmaceutics12060522.

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Nanofibrous biomaterials have huge potential for drug delivery, due to their structural features and functions that are similar to the native extracellular matrix (ECM). A wide range of natural and polymeric materials can be employed to produce nanofibrous biomaterials. This review introduces the major natural and synthetic biomaterials for production of nanofibers that are biocompatible and biodegradable. Different technologies and their corresponding advantages and disadvantages for manufacturing nanofibrous biomaterials for drug delivery were also reported. The morphologies and structures of nanofibers can be tailor-designed and processed by carefully selecting suitable biomaterials and fabrication methods, while the functionality of nanofibrous biomaterials can be improved by modifying the surface. The loading and releasing of drug molecules, which play a significant role in the effectiveness of drug delivery, are also surveyed. This review provides insight into the fabrication of functional polymeric nanofibers for drug delivery.

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Peer, Petra, Jana Sedlaříková, Magda Janalíková, Liliana Kučerová, and Pavel Pleva. "Novel Polyvinyl Butyral/Monoacylglycerol Nanofibrous Membrane with Antifouling Activity." Materials 13, no. 17 (August 19, 2020): 3662. http://dx.doi.org/10.3390/ma13173662.

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Monoacylglycerols (MAGs) have proven of great interest to the foodstuffs industry due to the promising antibacterial activity they show for controlling microbial contamination. Prior to this paper, this antibacterial agent had not been incorporated in a nanofibrous membrane. This study details convenient fabrication of nanofibrous membranes based on polyvinyl butyral (PVB) containing various concentrations of monocaprin (MAG 10) by an electrospinning process. Increasing the concentration of MAG 10 caused differences to appear in the shape of the nanofibers, in addition to which the level of wettability was heightened. Besides exhibiting antibacterial properties, the functional membranes demonstrated especially good antifouling activity. The novel and efficient nanofibrous membranes described have the potential to find eventual application in medical or environmental fields.

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Miszuk, Jacob M., Jue Hu, and Hongli Sun. "Biomimetic Nanofibrous 3D Materials for Craniofacial Bone Tissue Engineering." ACS Applied Bio Materials 3, no. 10 (September 2, 2020): 6538–45. http://dx.doi.org/10.1021/acsabm.0c00946.

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SI, Yang, XueQin WANG, FeiFei HONG, ChengCheng YAN, JianYong YU, and Bin DING. "Three-dimensional electrospun nanofibrous materials: Fabrication, properties, and applications." Chinese Science Bulletin 60, no. 21 (July 1, 2015): 1992–2002. http://dx.doi.org/10.1360/n972015-00340.

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Cui, Wenguo, Yue Zhou, and Jiang Chang. "Electrospun nanofibrous materials for tissue engineering and drug delivery." Science and Technology of Advanced Materials 11, no. 1 (February 2010): 014108. http://dx.doi.org/10.1088/1468-6996/11/1/014108.

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Paneva, Dilyana, Nevena Manolova, Mariana Argirova, and Iliya Rashkov. "Antibacterial electrospun poly(ɛ-caprolactone)/ascorbyl palmitate nanofibrous materials." International Journal of Pharmaceutics 416, no. 1 (September 2011): 346–55. http://dx.doi.org/10.1016/j.ijpharm.2011.06.032.

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Durán-Guerrero, J. G., M. A. Martínez-Rodríguez, M. A. Garza-Navarro, V. A. González-González, A. Torres-Castro, and Javier Rivera De La Rosa. "Magnetic nanofibrous materials based on CMC/PVA polymeric blends." Carbohydrate Polymers 200 (November 2018): 289–96. http://dx.doi.org/10.1016/j.carbpol.2018.08.015.

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Akduman, Çiğdem, Işık Özgüney, and E. Perrin Akçakoca Kumbasar. "Electrospun Thermoplastic Polyurethane Mats Containing Naproxen– Cyclodextrin Inclusion Complex." Autex Research Journal 14, no. 4 (December 1, 2014): 239–46. http://dx.doi.org/10.2478/aut-2014-0024.

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Abstract Incorporation of cyclodextrins (CDs) into electrospun nanofibrous materials can be considered as potential candidates for functional medical textile applications. Naproxen (NAP) is a type of non-steroidal anti-inflammatory drug commonly administered for the treatment of pain, inflammation and fever. Drug-inclusion complex formation with CDs is an approach to improve the aqueous solubility via molecular encapsulation of the drug within the cavity of the more soluble CD molecule. In this study, NAP or different NAP-CD inclusion complexes loaded nanofibres were successfully produced through electrospinning and characterised. The inclusion complex loaded mats exhibited significantly faster release profiles than NAP-loaded thermoplastic polyurethane (TPU) mats. Overall, NAP-inclusion complex loaded TPU electrospun nanofibres could be used as drug delivery systems for acute pain treatments since they possess a highly porous structure that can release the drug immediately.

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Lyu, Chenxin, Peng Zhao, Jun Xie, Shuyuan Dong, Jiawei Liu, Chengchen Rao, and Jianzhong Fu. "Electrospinning of Nanofibrous Membrane and Its Applications in Air Filtration: A Review." Nanomaterials 11, no. 6 (June 6, 2021): 1501. http://dx.doi.org/10.3390/nano11061501.

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Air pollution caused by particulate matter and toxic gases is violating individual’s health and safety. Nanofibrous membrane, being a reliable filter medium for particulate matter, has been extensively studied and applied in the field of air purification. Among the different fabrication approaches of nanofibrous membrane, electrospinning is considered as the most favorable and effective due to its advantages of controllable process, high production efficiency, and low cost. The electrospun membranes, made of different materials and unique structures, exhibit good PM2.5 filtration performance and multi-functions, and are used as masks and filters against PM2.5. This review presents a brief overview of electrospinning techniques, different structures of electrospun nanofibrous membranes, unique characteristics and functions of the fabricated membranes, and summarization of the outdoor and indoor applications in PM filtration.

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Pabjańczyk-Wlazło, Ewelina, Izabella Krucińska, Michał Chrzanowski, Grzegorz Szparaga, Agata Chaberska, Beata Kolesińska, Agnieszka Komisarczyk, and Maciej Boguń. "Fabrication of Pure Electrospun Materials from Hyaluronic Acid." Fibres and Textiles in Eastern Europe 25 (June 30, 2017): 45–52. http://dx.doi.org/10.5604/01.3001.0010.1688.

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The aim of the research was to develop optimal conditions for manufacturing materials based on hyaluronic acid by the electrospun method. The studies were composed of three stages: the process of selection of the optimal solvent (mixture of solvents), the molecular weight of hyaluronic acid, and the concentration of biopolymer in the spinning solution. The influence of variable parameters on the rheological properties of the spinning solutions and electrospinning trails was tested. Depending on the electrospinning regime applied, the fibers obtained were characterised by a diameter of the order of 20 to 400 nm. As a result of the development works presented, an optimal molecular weight of the polymer, its concentration and system of solvents were determined, together with process parameters, ensuring a stable electrospinning process and relatively homogeneous nanofibers. Additionally studies on the residues of solvents used during electrosun formation were done and parameters of drying of the final materials were examined. This approach (verification of the presence oforganic solvent residue in the nanofibrous formed) is important for the suitability of nanofibres as scaffolds for regenerative medicine. This study provides an opportunity for the understanding and identification of process parameters, allowing for predictable manufacturing nanofibers based on natural biopolymers, which makes it tremendously beneficial in terms of customisation.

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