Academic literature on the topic 'Nanofibres of chitosan'

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Journal articles on the topic "Nanofibres of chitosan":

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Cheng, Tong, Rolf-Dieter Hund, Dilibaier Aibibu, Jana Horakova, and Chokri Cherif. "Pure Chitosan and Chitsoan/Chitosan Lactate Blended Nanofibres made by Single Step Electrospinning." Autex Research Journal 13, no. 4 (December 31, 2013): 128–33. http://dx.doi.org/10.2478/v10304-012-0040-6.

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Abstract A single step electrospinning of chitosan and chitosan derivative-chitosan lactate nanofibres was studied in this paper. Chitosan was dissolved into acetic acid to produce structure-stable nanofibres. The effect of chitosan concentration and the content of acetic acid on the fibre diameter and morphology of nanofibres were studied in detail. The dynamic viscosity and surface tension of the electrospinning chitosan solutions were systematically studied as well. Based on the fundamental study on electrospinning chitosan in acetic acid, a chitosan derivative, chitosan lactate, was added to produce nanofibre in a pH-friendly aqueous environment. Chemical and morphological analyses demonstrated that chitosan lactate will positively influence the formation of nanofibres in higher pH condition although the morphology should be improved.
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Che, Ai-Fu, Xiao-Jun Huang, Zhen-Gang Wang, and Zhi-Kang Xu. "Preparation and Surface Modification of Poly(acrylonitrile-co-acrylic acid) Electrospun Nanofibrous Membranes." Australian Journal of Chemistry 61, no. 6 (2008): 446. http://dx.doi.org/10.1071/ch07226.

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Poly(acrylonitrile-co-acrylic acid) (PANCAA) was synthesized and fabricated into nanofibrous membranes by an electrospinning technique. Scanning electron microscopy revealed that membranes composed of uniformly thin and smooth nanofibres were obtained under optimized processing parameters. Surface modification with chitosan on these nanofibrous membranes was accomplished by a coupling reaction between the carboxylic groups of PANCAA and the primary amino groups of chitosan. Fluorescent labelling, weight measurement, FT-IR/ATR spectroscopy, and X-ray photoelectron spectroscopy (XPS) were used to confirm the modification process and determine the immobilization degree of chitosan. Platelet adhesion experiments were further carried out to evaluate the hemocompatibility of the studied nanofibrous membranes. Preliminary results indicated that the immobilization of chitosan on the PANCAA nanofibrous membranes was favourable for platelet adhesion.
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Korniienko, Viktoriia, Yevheniia Husak, Anna Yanovska, Şahin Altundal, Kateryna Diedkova, Yevhen Samokhin, Yuliia Varava, Viktoriia Holubnycha, Roman Viter, and Maksym Pogorielov. "BIOLOGICAL BEHAVIOUR OF CHITOSAN ELECTROSPUN NANOFIBROUS MEMBRANES AFTER DIFFERENT NEUTRALISATION METHODS." Progress on Chemistry and Application of Chitin and its Derivatives 27 (September 30, 2022): 135–53. http://dx.doi.org/10.15259/pcacd.27.010.

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Chitosan electrospun nanofibres were synthesised in two different trifluoroacetic acid (TFA)/dichloromethane (DCM) solvent ratios and then neutralised in aqueous and ethanol sodium-based solutions (NaOH and Na2CO3) to produce insoluble materials with enhanced biological properties for regenerative and tissue engineering applications. Structural, electronic, and optical properties and the swelling capacity of the prepared nanofibre membrane were studied by scanning electron microscopy, Fourier-transform infrared spectroscopy, and photoluminescence. Cell viability (with the U2OS cell line) and antibacterial properties (against Staphylococcus aureus and Escherichia coli) assays were used to assess the biomedical potential of the neutralised chitosan nanofibrous membranes. A 7:3 TFA/DCM ratio allows for an elaborate nanofibrous membrane with a more uniform fibre size distribution. Neutralisation in aqueous NaOH only maintains a partial fibrous structure. At the same time, neutralisation in NaOH ethanol-water maintains the structure during 1 month of degradation in phosphate-buffered saline and distilled water. All membranes demonstrate high biocompatibility, but neutralisation in ethanol solutions affects cell proliferation on materials made with 9:1 TFA/DCM. The prepared nanofibrous mats could constrain the growth of both gram-positive and gram-negative microorganisms, but 7:3 TFA/DCM membranes inhibited bacterial growth more efficiently. Based on structural, degradation, and biological properties, 7:3 TFA/DCM chitosan nanofibrous membranes neutralised by 70% ethanol/30% aqueous NaOH exhibit potential for biomedical and tissue engineering applications.
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Hild, Martin, Mohammed Fayez Al Rez, Dilbar Aibibu, Georgios Toskas, Tong Cheng, Ezzedine Laourine, and Chokri Cherif. "Pcl/Chitosan Blended Nanofibrous Tubes Made by Dual Syringe Electrospinning." Autex Research Journal 15, no. 1 (March 1, 2015): 54–59. http://dx.doi.org/10.1515/aut-2015-0016.

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Abstract 3D tubular scaffolds made from Poly-(Ɛ-caprolactone) (PCL)/chitosan (CS) nanofibres are very promising candidate as vascular grafts in the field of tissue engineering. In this work, the fabrication of PCL/CS-blended nanofibrous tubes with small diameters by electrospinning from separate PCL and CS solutions is studied. The influence of different CS solutions (CS/polyethylene glycol (PEO)/glacial acetic acid (AcOH), CS/trifluoroacetic acid (TFA), CS/ AcOH) on fibre formation and producibility of nanofibrous tubes is investigated. Attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR) is used to verify the presence of CS in the blended samples. Tensile testing and pore size measurements are done to underline the good prerequisites of the fabricated blended PCL/ CS nanofibrous tubes as potential scaffolds for vascular grafts. Tubes fabricated from the combination of PCL and CS dissolved in AcOH possesses properties, which are favourable for future cell culture studies.
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Nthunya, Lebea N., Monaheng L. Masheane, Soraya P. Malinga, Tobias G. Barnard, Edward N. Nxumalo, Bhekie B. Mamba, and Sabelo D. Mhlanga. "UV-assisted reduction of in situ electrospun antibacterial chitosan-based nanofibres for removal of bacteria from water." RSC Advances 6, no. 98 (2016): 95936–43. http://dx.doi.org/10.1039/c6ra19472a.

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Jacobs, Valencia, Asis Patanaik, Rajesh D. Anandjiwala, and Malik Maaza. "Optimization of Electrospinning Parameters for Chitosan Nanofibres." Current Nanoscience 7, no. 3 (June 1, 2011): 396–401. http://dx.doi.org/10.2174/157341311795542570.

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PROKOPCHUK, N. R., ZH S. SHASHOK, D. V. PRISHСHEPENK, and V. D. MELAMED. "NANOFIBRES ELECTROSPINNING FROM CHITOSAN SOLUTIONS (A REVIEW)." Polymer materials and technologies 1, no. 2 (2015): 36–56. http://dx.doi.org/10.32864/polymmattech-2015-1-2-36-56.

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Salehi, Majid, Saeed Farzamfar, Arian Ehterami, Zahrasadat Paknejad, Farshid Bastami, Sadegh Shirian, Hamid Vahedi, Gholamreza Savari Koehkonan, and Arash Goodarzi. "Kaolin-loaded chitosan/polyvinyl alcohol electrospun scaffold as a wound dressing material: in vitro and in vivo studies." Journal of Wound Care 29, no. 5 (May 2, 2020): 270–80. http://dx.doi.org/10.12968/jowc.2020.29.5.270.

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Objective: To evaluate the application of a fabricated dressing containing kaolin for skin regeneration in a rat model of excisional wounds. Method: In the present study, kaolin was loaded into electrospun polyvinyl alcohol (PVA)/chitosan polymer blend to develop a composite nanofibrous dressing. To make the yarns, kaolin with weight ratio of 5% was added to PVA/chitosan polymer blend and subsequently formed into nanofibres using the electrospinning method. Scaffolds were evaluated for to their microstructure, mechanical properties, surface wettability, water vapour transmission rate, water-uptake capacity, blood uptake capacity, blood compatibility, microbial penetration test, the number of colonies, and cellular response with the L929 cell line. Rats with full-thickness excisional wounds were treated with kaolin-containing and kaolin-free dressings. Results: The study showed that rats treated with the kaolin-incorporated mats demonstrated a significant closure to nearly 97.62±4.81% after 14 days compared with PVA/chitosan and the sterile gauze, which showed 86.15±8.11% and 78.50±4.22% of wound closure, respectively. The histopathological studies showed that in the PVA/chitosan/kaolin group, dense and regular collagen fibres were formed, while wounds treated with sterile gauze or PVA/chitosan scaffolds had random and loose collagen fibres. Conclusion: Our results show the potential applicability of PVA/chitosan/kaolin scaffolds as a wound care material.
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Abdelgawad, Abdelrahman M., Mehrez E. El-Naggar, Samuel M. Hudson, and Orlando J. Rojas. "Fabrication and characterization of bactericidal thiol-chitosan and chitosan iodoacetamide nanofibres." International Journal of Biological Macromolecules 94 (January 2017): 96–105. http://dx.doi.org/10.1016/j.ijbiomac.2016.07.061.

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Fras Zemljič, Lidija, Uroš Maver, Tjaša Kraševac Glaser, Urban Bren, Maša Knez Hrnčič, Gabrijela Petek, and Zdenka Peršin. "Electrospun Composite Nanofibrous Materials Based on (Poly)-Phenol-Polysaccharide Formulations for Potential Wound Treatment." Materials 13, no. 11 (June 9, 2020): 2631. http://dx.doi.org/10.3390/ma13112631.

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In this paper, we focus on the preparation of electrospun composite nanofibrous materials based on (poly)-phenol-polysaccharide formulation. The prepared composite nanofibres are ideally suited as a controlled drug delivery system, especially for local treatment of different wounds, owing to their high surface and volume porosity and small fibre diameter. To evaluate the formulations, catechin and resveratrol were used as antioxidants. Both substances were embedded into chitosan particles, and further subjected to electrospinning. Formulations were characterized by determination of the particle size, encapsulation efficiency, as well as antioxidant and antimicrobial properties. The electrospinning process was optimised through fine-tuning of the electrospinning solution and the electrospinning parameters. Scanning electron microscopy was used to evaluate the (nano)fibrous structure, while the successful incorporation of bio substances was assessed by X-ray Photoelectron Spectroscopy and Fourier transform infrared spectroscopy. The bioactive properties of the formed nanofibre -mats were evaluated by measuring the antioxidative efficiency and antimicrobial properties, followed by in vitro substance release tests. The prepared materials are bioactive, have antimicrobial and antioxidative properties and at the same time allow the release of the incorporated substances, which assures a promising use in medical applications, especially in wound care.

Dissertations / Theses on the topic "Nanofibres of chitosan":

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Mafuma, Tendai Simbarashe. "Immobilisation of electric eel acetylcholinesterase on nanofibres electrospun from a nylon and chitosan blend." Thesis, Rhodes University, 2013. http://hdl.handle.net/10962/d1001620.

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Organophosphates and carbamates are potent inhibitors of the neurotransmitter acetylcholinesterase. This inhibition results in the blocking of nerve signal transference into the post synaptic neuron leading to loss of muscle action and death. Because of the universal mechanisms of signal transduction in animals, these inhibitors have been widely used as agricultural pesticides as well as chemical warfare agents (nerve agents). Health issues associated with pesticide usage result from the fact that both the pesticides and their breakdown products often end up in water and food sources as well as in the soil. As a result, there has been an increase in the number of studies aimed at the detection of these pesticides in the environment. One popular research area is enzyme based biosensor construction. Some important criteria for consideration during the construction of biosensors are the importance of a suitable solid support as well as the enzyme immobilisation method. Recently, there has been increased interest in using nano-scale material e.g. using nanoparticles as enzyme support material. This is largely due to their advantages such as large surface area to volume ratio as well as reduced mass transfer resistance. Electrospinning is a straight forward and cost effective method for producing nanofibres from any soluble polymer(s). The applications of electrospun nanofibres have been reported in clinical studies, biofuel production as well as bioremediation. In this study two polymers were selected: nylon for its mechanical stability and chitosan for its biocompatibility and hydrophilicity, for the fabrication of electrospun nanofibres which would function as immobilisation support material for acetylcholinesterase. The first objective of this study was to electrospin nanofibres from a nylon-6 and chitosan blend solution. A binary solvent system consisting of formic acid and acetic acid (50:50) successfully dissolved and blended the polymers which were subsequently electrospun. Scanning electron microscopy characterisation of the nanofibres showed that (i) a nylon-6: chitosan ratio of 16%: 3% resulted in the formation of bead free nanofibres and (ii) the fibres were collected in non-woven mats characterised by different size nanofibres with average diameters of 250 nm for the main fibres and 40 nm for the smaller nanofibres. Fourier transform infra-red (FT-IR) analysis of the nanofibres indicated that a new product had been formed during the blending of the two polymers. The second aim of the study was to carry out a facile immobilisation of electric eel acetylcholinesterase via glutaraldehyde (GA) cross-linking. Glutaraldehyde solution 5% (v/v) resulted in the immobilisation of 0.334 mg/cm² of acetylcholinesterase onto the nanofibres. The immobilisation procedure was optimised with reference to acetylcholinestease and crosslinker concentrations, incubation time and the cross-linking method. A comparative investigation into the optimum pH and temperature conditions, pH and thermal stabilities, substrate and inhibition kinetics was then carried out on free and immobilised acetylcholinesterase. The final objective of this study was to determine the storage stabilities of the immobilised and free enzymes as well as the reusability characteristics of the immobilised acetylcholinesterase. Several conclusions were drawn from this study. Acetylcholinesterase was successfully immobilised onto the surface of nylon-6:chitosan nanofibres with retention of its activity. There was a shift in the pH optimum of the immobilised acetylcholineseterase by 0.5 units towards a neutral pH. Although both free and immobilised acetylcholinesterase exhibited the same optimum temperature, immobilised acetylcholinesterase showed enhanced thermal stability. In terms of pH stability, immobilised acetylcholinesterase showed greater stability at acidic pH whilst free acetylcholinesterase was more stable under alkaline pH conditions. Relative to free acetylcholinesterase, the immobilised enzyme showed considerable storage stability retaining ~50% of its activity when stored for 49 days at 4°C. Immobilised acetylcholinesterase also retained > 20% of its initial activity after 9 consecutive reuse cycles. When exposed to fixed concentrations of carbofuran or demeton-S-methyl sulfone, immobilised acetylcholinesterase showed similar inhibition characteristics to that of the free enzyme. The decrease in enzyme activity observed after immobilisation to the nanofibres may have been due to several reasons which include some enzyme molecules being immobilised in structural conformations which reduced substrate access to the catalytic site, participation of the catalytic residues in immobilisation and enzyme denaturation due to the reaction conditions used for acetylcholinesterase immobilisation. Similar observations have been widely reported in literature and this is one of the major drawbacks of enzyme immobilisation. In conclusion, nylon-6:chitosan electrospun nanofibres were shown to be suitable supports for facile acetylcholinesterase immobilisation and the immobilised enzyme has potential for use in pesticide detection. Future recommendations for this study include a comparative study of the GA cross-linking method for AChE immobilisation which will lead to more intensely bound enzyme molecules to prevent non-specific binding. An investigation into the effect of inhibitors on stored immobilised AChE, as well as reactivation and reuse studies, may also be useful for determining the cost-effectiveness of reusing immobilised AChE for pesticide detection in environmental water samples. Several models have been designed for the determination of the kinetic parameters for immobilised enzymes. These take into account the mass transfer resistance as well as the overall charge of the immobilisation matrix. The use of these models to analyse experimental data will give a clear understanding of the effects of immobilisation on enzyme activity
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Ouerghemmi, Safa. "Electrospinning du chitosan pour l’élaboration de réseaux de nanofibres à activités antibactérienne et antithrombotique." Thesis, Lille 1, 2016. http://www.theses.fr/2016LIL10199.

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Les biomatériaux sont très largement utilisés dans le soin de maladies, de brûlures ou de blessures. Ils sont utilisés sous la forme de dispositifs médicaux destinés à des applications extra ou intra corporelles : pansement, prothèses vasculaire, filet de réparation de hernie, ligament artificiel etc.. Ils se doivent donc notamment d’être biocompatibles et hémocompatibles, mais la recherche vise actuellement à leur apporter des propriétés bioactives supplémentaires (antibactérienne, anti inflammatoire, anti-thrombotique, régénérative etc.). Le chitosan (CHT) est un polymère cationique biosourcé couramment utilisé en tant que biomatériau pour ses propriétés biologiques intrinsèques (biocompatible, bio résorbable, antibactérien, hémostatique, pro-cicatrisant). Dans ce contexte, nous avons élaboré deux types de membranes bioactives (antibactérienne et anti thrombotique) constituées d’enchevêtrements de nanofibres (NFs) à base de chitosan grâce à la technologie innovante de l’electrospinning. Premièrement, des NF antibactériennes ont été élaborées par association du CHT avec un polymère anionique de cyclodextrine (PCD), molécule cage connue pour piéger puis libérer de façon ralentie des molécules bioactives. Deux types de NFs chargées en triclosan (TCL) choisi comme principe actif antibactérien ont été préparées : 1) par mélange homogène CHT+PCD/TCL, ou en structure cœur-peau avec [PCD/TCL] en cœur, et [CHT] en peau. Deuxièmement, des NFs à activité anti-thrombotiques ont été obtenues en modifiant chimiquement le CHT par des fonctions sulfonates qui ont apporté des propriétés anticoagulantes similaires à celles de l’héparine (heparin-like), suivi de l’étape d’électrofilage
Biomaterials are designed to cure people suffering from chronic diseases or suffer injuries or burns. They are developed for intra or extra bodily applications (wound dressings, vascular prostheses, inguinal meshes artificial ligaments etc.). Thus, they must be biocompatible and hemocompatible at first, but research presently aims to give them additional properties (antibacterial, anti-thrombotic, regenerative). Chitosan (CHT) is a cationic biosourced polymer commonly used for these applications thanks to its intrinsic biological properties (biocompatible, bioresorbable, antibacterial, hemostatic, healing)In this context, we developed two kinds of bioactive membranes based on chitosan nanofibers by using the innovative electrospinning technology. Firtsly antibacterial NF have been obtaines by associating CHT with a anionic cyclodextrin polymer (PCD), known to trap and slowly release some bioactive compounds. Twotwo kinds of NFs loaded with triclosan (TCL) have been prepared: mixed CHT+PCD/TCL and core-sheath with PCD/TCL in core, and [CHT] as sheath. Secondly, antithrombotic NFs have been elaborated by chemically modifying CHT with sulfonate groups giving heparin-like properties to the NFs after electrospinning
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Dimassi, Syrine. "Membranes bioactives à propriétés antithrombotiques ou ostéoinductrices élaborées par electrospinning." Electronic Thesis or Diss., Université de Lille (2018-2021), 2018. http://www.theses.fr/2018LILUR072.

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Les textiles sont utilisés dans le domaine biomédical, notamment pour le soin des plaies ou pour la conception de prothèses de substitution ou de régénération d’organes endommagés par la maladie ou par cause accidentelle. Le cahier des charges des textiles médicaux évolue vers l’élaboration de biomatériaux biorésorbables et bioactifs capables d’interagir spécifiquement avec les tissus vivants en fonction de leur nature. Dans ce contexte, le projet de recherche consiste à concevoir, par electrospinning, deux types de membranes nanofibreuses bioactives à base de chitosane. Dans une première approche, des nanofibres de chitosane à ont été fonctionnalisées par la polydopamine qui contient des groupements catéchols capables d’induire la biominéralisation in vitro dans un milieu riche en ions calcium et phosphate. Ces membranes à propriétés ostéoinductrices pourraient être utilisées comme scaffolds pour la régénération tissulaire guidée en parodontologie. Dans une deuxième approche, l’élaboration de nanofibres à propriétés anticoagulantes à base de chitosane a été menée. Le chitosane a été d’abord chimiquement modifié par des groupements sulfonates. Les paramètres de synthèse ont permis de contrôler le degré de sulfonation du chitosane et ses nouvelles propriétés caractéristiques d’un polyampholyte ont été observées. Les essais biologiques effectués ont montré que ces dérivés sulfoniques sont non hémolytiques et bénéficient de propriétés anticoagulantes. Puis, des nanofibres de chitosane sulfoné ont été obtenues par electrospinning conduisant à des membranes à propriétés antithrombotiques, ce qui en fait des candidats de choix pour la fonctionnalisation de stents vasculaires
Textiles are widely used in the biomedical field, in particular for the care of wounds or the design of prostheses for strengthening or regenerating organs damages by the disease of by accidental cause. The specifications for medical textile are evolving towards the development of bioresorable and bioactive biomaterials that are capable of interacting with living tissues according to their nature. In this context, the research project consists of generating, by electrospinning, two types of biomimetic and bioactive nanofibrous membranes based on chitosan. In a first approach, nanofibres of chitosan have been functionalized by polydopamine that contains catechol groups capable of inducing the in vitro biomineralization in a medium rich in calcium and phosphate ions. Thus, these nanofibrous membranes with osteoinductive properties could be used as scaffolds for guided tissue engineering in periodontology. In a second approach, the development of chitosan-based nanofibers with anticoagulant properties was conducted. Chitosan was initially chemically modified by sulfonate groups. The synthesis parameters allowed to control the degree of sulfonation of chitosan and its new polyampholyte specific character was observed. The different biological assays carried out have shown that these sulfonic derivatives are non-hemolytic and benefit from anticoagulant properties. Then, sulfonated chitosan-based nanofibres were obtained by electrospinning leading to membranes with antithrombotic properties, make them suitable candidates for the functionalization of vascular stents
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Prokopchuk, N. R., Zh S. Shashok, K. V. Vishnevskii, and D. V. Prishchepenko. "Formation of Chitosan Nanofibers by Electrospinning Method." Thesis, Sumy State University, 2015. http://essuir.sumdu.edu.ua/handle/123456789/42652.

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The paper presents the results of the preparation of the nanofiber coatings from chitosan biopolymer by electro-spinning. Structure and uniformity distribution of the fibers in the resulting coatings are investigated by a scanning electron microscope JEOL JSM-5610 LV. The optimum concentration of the chitosan solution in the mold, which provide forming nanofibers with fewer defects, was determinated. The obtained data are used for the development of the technology for production of hemostatic and wound-healing dressings for medical purposes in order to organize their production at OJSC "Mineral Wax Plant".
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Scheidt, Desiree Tamara. "Eletrofiação da quitosana e sua aplicação como curativo para feridas." Universidade Estadual do Oeste do Paraná, 2018. http://tede.unioeste.br/handle/tede/4018.

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Fundação Araucária de Apoio ao Desenvolvimento Científico e Tecnológico do Estado do Paraná (FA)
Nanofibers generated using polymers are generally produced by the electrospinning method. It is a simple, economical and versatile technique that uses an electric force to generate ultrafine fibers. Chitosan is a non-toxic, biodegradable, biocompatible polymer obtained from renewable natural sources that attracts the interest of researchers. However, due to the difficulty of electrospinning pure chitosan, it has been tried to ally the poly (ethylene oxide) PEO to the polymeric matrix of chitosan, in order to facilitate the process of obtaining fibers. In this context, the initial objective of this work was to obtain a polymeric blends containing chitosan and PEO capable of generating nanofibers when subjected to the electrospinning process. The poly (ethylene oxide) was excellent as a helper in chitosan spinning, allowing the obtaining of fibers with up to 90% of the same and the average diameter obtained was of 320nm. The process parameters were evaluated and the ones that showed the best result were a concentration of 4% of chitosan and 2% of PEO, applied tension of 18kv and distance between the collector and needle of 20cm. The incorporation of PEO into the polymeric matrix of chitosan proved to be an effective strategy for obtaining nanofibers by the electrophilic process. The study was then carried out for the incorporation of the drug neomycin sulfate into the electrophilic matrix. Membranes in the ratio of 90/10 (v / v) chitosan / 4% PEO / 4% (m / v), as well as membranes in the ratio 80/20 (v / v) chitosan / PEO (4% / 2%) were studied as support for the incorporation of the drug. When the neomycin sulfate was incorporated together with the solution and subjected to electrospinning, the diameter of the fibers obtained were even smaller, with a mean of 258nm. The obtained membranes were subjected to physico-chemical analysis, which proved the miscibility of the polymers chitosan and PEO as well as confirmed the incorporation of the neomycin sulfate to the blend. The antimicrobial activity for the drug and non-drug membranes was investigated against Gram positive and Gram negative bacteria and the registered inhibition halos were larger or near the control. The neomycin sulfate release test indicated that it had a rapid release profile, and with only 120 minutes, much of the drug had already been released from the polymer film. In view of this, the membranes developed in this study suggest to be promising candidates for the application as a biomaterial in wound healing.
Nanofibras poliméricas podem ser produzidas utilizando o método de eletrofiação. Trata-se de uma técnica simples, econômica e versátil que utiliza um potencial elétrico para gerar fibras em escala nanométrica. Dentre os polímeros eletrofiados, pode-se destacar a quitosana, a qual é um polímero atóxico, biodegradável, biocompatível, obtido por meio de fontes naturais renováveis, que vem despertando o interesse de pesquisadores. No entanto, devido à dificuldade de eletrofiação desse material puro, tem-se buscado aliar o poli (óxido de etileno) PEO à matriz polimérica da quitosana, a fim de se facilitar o processo de obtenção de fibras. Nesse contexto, o objetivo inicial deste trabalho foi a obtenção de uma blenda polimérica contento quitosana e PEO capaz de gerar nanofibras quando sujeitas ao processo de eletrofiação. O poli (óxido de etileno) mostrou-se excelente como auxiliador na fiação da quitosana, permitindo a obtenção de fibras com até 90% da mesma e o diâmetro médio obtido foi de 320nm. Os parâmetros de processo foram avaliados e os que mostraram melhor resultado foi uma concentração de 4% (m/v) de quitosana em ácido acético 90% (v/v) e 2% (m/v) de PEO em ácido acético 50% (v/v), tensão aplicada foi de 18kV e distância entre o coletor e agulha de 20cm. A incorporação do PEO à matriz polimérica de quitosana se mostrou, então, uma estratégia eficaz para a obtenção de nanofibras por meio do processo de eletrofiação. Seguiu-se então o estudo para a incorporação do fármaco sulfato de neomicina à matriz eletrofiada, com a finalidade de ampliar a atividade antimicrobiana do filme obtido. Membranas na proporção 90/10 (v/v) de quitosana/PEO 4%/4% (m/v), assim como membranas na proporção 80/20 (v/v) quitosana/PEO 4%/2% (m/v) foram estudadas como suporte para a incorporação do fármaco. Quando o sulfato de neomicina foi incorporado junto a solução e submetido a eletrofiação, o diâmetro das fibras obtidas foram ainda menores, com média de 258nm. As membranas obtidas foram sujeitas a análises físico-químicas, as quais comprovarem a miscibilidade dos polímeros quitosana e PEO assim como confirmaram a incorporação do sulfato de neomicina à blenda. A atividade antimicrobiana para as membranas com fármaco e sem fármaco foi investigada contra bactérias Gram positivas e Gram negativas e os halos de inibição registrados foram maiores ou próximo ao controle, demonstrando uma alta capacidade antimicrobiana. O teste de liberação do sulfato de neomicina indicou que o mesmo apresenta um perfil de liberação rápido, sendo que com apenas 120 minutos grande parte do fármaco já havia se desprendido do filme polimérico. Diante disso, as membranas desenvolvidas nesse estudo sugerem ser promissoras candidatas para a aplicação como um biomaterial na cicatrização de feridas, sendo ainda necessários estudos de viabilidade celular.
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Ridolfi, Daniela Missiani 1985. "Produção e caracterização de nanofibras de quitosana com nanocristais de celulose para aplicações biomédicas." [s.n.], 2014. http://repositorio.unicamp.br/jspui/handle/REPOSIP/248938.

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Orientador: Nelson Eduardo Durán Caballero
Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Química
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Resumo: Neste trabalho nanofibras de quitosana/poli (óxido de etileno) (PEO) (5:1) com nanocristais de celulose (NCC) foram produzidas com sucesso por eletrofiação e foi verificado o efeito da adição dos NCC nas propriedades das nanofibras obtidas. Os ensaios de eletrofiação foram realizados com amostras de NCC obtidas por hidrólise ácida. A eletrofiação de soluções de quitosana, sem e com NCC, resultaram na formação de muitas gotas (beads). Portanto, foi necessário adicionar o PEO nas soluções. Embora a adição de PEO tenha favorecido a formação de fibras, as soluções de quitosana/PEO sem NCC geraram também gotas enquanto que as soluções de quitosana/PEO contendo NCC resultaram em fibras uniformes. As soluções de quitosana/PEO com NCC apresentaram maior viscosidade em relação à solução sem NCC, o que pode ter favorecido a formação de fibras uniformes. As soluções de quitosana/PEO contendo 10% (m/m) de NCC produziram fibras mais finas em relação às soluções com 5% (m/m) de NCC provavelmente devido à maior condutividade da solução. Análises termogravimétricas mostraram que os NCC interferem na decomposição do PEO, mas sem prejudicar o desempenho do material. As nanofibras de quitosana/PEO contendo NCC apresentaram menor cristalinidade em relação às nanofibras sem NCC. Resultados de ensaios com células em culturas de fibroblastos 3T3 mostraram que as nanofibras de quitosana/PEO (com 10% de NCC) promoveram a adesão celular e mantiveram a morfologia celular característica o que sugere um potencial dessas nanofibras para aplicações em engenharia de tecidos
Abstract: In this work chitosan/ poly (ethylene oxide) (PEO) (5:1) nanofibers with cellulose nanocrystals (CNC) were successfully produced by the electrospinning technique and the effect of the addition of CNC on the nanofibers properties was evaluated. The electrospinning assays were performed with samples of CNC obtained by acid hydrolysis. The electrospinning of chitosan solutions, with and without CNC, resulted in the formation of many drops (beads). Therefore, it was necessary to add PEO on solutions. Although the PEO addition has favored the fiber formation, the chitosan/PEO solutions without CNC showed beads while chitosan/PEO solutions with CNC resulted in uniform fibers. The chitosan/PEO solutions with CNC showed higher viscosity compared to the solution without CNC, which may have favored the formation of uniform fibers. Solutions of chitosan/PEO containing 10% (w/w) of CNC produced thinner fibers compared to solutions containing 5% (w/w) of CNC probably due the higher solution conductivity. Thermogravimetric analysis (TGA) showed that the CNC has an effect on the PEO decomposition, however, it does not impair the performance of the material. The chitosan/PEO nanofibers with CNC showed lower crystallinity compared the nanofibers without CNC. Results from cell assay in cultures of 3T3 fibroblasts showed that the chitosana/PEO nanofibers (with 10% of CNC) promoted cell attachment and maintained the characteristic cell morphology which suggests potential applications of these nanofibers in cell tissue engineering
Doutorado
Físico-Química
Doutora em Ciências
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Sato, Tabata Do Prado. "Desenvolvimento de biomateriais à base de quitosana : matriz de fibras eletrofiadas para regeneração tecidual e de hidrogel coacervado para entrega controlada de fármaco /." São José dos Campos, 2019. http://hdl.handle.net/11449/191168.

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Orientador: Alexandre Luiz Souto Borges
Coorientador: Artur José Monteiro Valente
Banca: Bruno Vinícius Manzolli Rodrigues
Banca: Fernanda Alves Feitosa
Banca: Lafayette Nogueira Júnior
Banca: Eduardo Shigueyuki Uemura
Resumo: Os atuais avanços no desenvolvimento de biomateriais caminham para 2 áreas promissoras: a de regeneração tecidual e a de entrega controlada de fármacos. Assim, o presente estudo objetivou a síntese e caracterização de diferentes matrizes (fibras e hidrogel) à base de quitosana, a fim de se obter materiais biomiméticos para atuação em ambas áreas. Para regeneração, delineou-se a síntese de um arcabouço de fibras de quitosana com e sem cristais de nanohidroxiapatita onde, para isso, foram eletrofiadas soluções de quitosana (Ch) e de quitosana com nanohidroxiapatita (ChHa). Os espécimes de Ch apresentaram maior homogeneidade e maior diâmetro médio de fibras (690 ± 102 nm) que ChHa (358 ± 49 nm). No teste de viabilidade celular e na atividade da fosfatase alcalina não houve diferença estatística entre os grupos experimentais (Ch e ChHa), porém ambos diferiram do grupo controle (p < 0,001). Para o âmbito de liberação de fármacos, sintetizou-se, pela técnica de emulsão, dois tipos de hidrogéis: o primeiro, uma mistura da fase aquosa da solução de Ch (1 mL) e da solução de DNA (1 mL) (1:1) e o segundo, mistura da fase aquosa da solução de Ch (1 mL) e solução de Pectina (1 mL) (1:1). Ambas misturas foram realizadas em álcool benzílico (5 mL) com instrumento de dispersão de alto desempenho (31-34000 rpm min-1 por 5 min). Após a obtenção dos géis, 20mg de cada grupo foram imersos em uma solução aquosa de Própolis Verde (PV), na concentração de 70 μg/mL por 2 h e a cinética de liberação... (Resumo completo, clicar acesso eletrônico abaixo)
Current advances in biomaterial development are moving to 2 promising areas: tissue regeneration and controlled drug delivery. Thus, the present study aimed the synthesis and characterization of different matrices (fibers and hydrogel) based on chitosan, in order to obtain biomimetic materials for performance in both areas. For regeneration, the synthesis of a scaffold of chitosan fibers with and without nanohydroxyapatite crystals was delineated, where chitosan (Ch) and chitosan with hydroxyapatite (ChHa) solutions were electrospun. Ch specimens presented higher homogeneity and larger mean fiber diameter (690±102nm) than ChHa (358 ± 49nm). In the cell viability test and alkaline phosphatase activity there was no statistical difference between the experimental groups. (Ch and ChHa), but both differed from the control group (p < 0,001). For the drug release scope, two types of hydrogels were synthesized by the emulsion technique: the first, a mixture of the aqueous phase of Ch solution (1 mL) and DNA solution (1 mL) (1:1) and the second, mixture of the aqueous phase of the Ch solution (1mL) and Pectin solution (1 mL) (1:1). Both mixtures were performed in benzyl alcohol (5 mL) with high performance dispersion instrument (31-34000 rpm min-1 for 5 min). After obtaining the gels, 20mg from each group were immersed in an aqueous solution of Propolis Green (PV), at a concentration of 70 µg/mL for 2 h and the release kinetics of PV were analyzed at 25 and 37oC in water and artificial saliva. The obtained specimens were lyophilized and then physically-chemically characterized. The presence of pectin and DNA was confirmed by FTIR. PV sorption induced a significant modification of the gel surface. A phase separation was found between chitosan and DNA. Encapsulation efficiency did not change significantly between 25 and 37oC. The release kinetics in water or saliva presented a two-step mechanism. And the biological results...
Doutor
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Paraboon, Jirapun. "Biomedical Application of Nanofiber." University of Akron / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=akron1280928465.

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Tung, Wing-tai, and 董永泰. "Preparation of electrospun chitosan fibres for Schwann cell-guided axonal growth." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/208170.

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Schwann cell-seeded guidance channels have been exploited to bridge and guide axonal re-growth across gaps in lesioned nerves. Mis-orientation of Schwann cells in the channels can however distort axonal growth within the lesion. We therefore propose to orient the growth of Schwann cells on aligned nanofibers such that axonal growth can be guided along the designated direction towards the target. Chitosan was the choice scaffold material given its biocompatibility and the tunable susceptibility to biodegradation. To be suitable for electrospinning, chitosan was dissolved in trifluoroacetic acid/methylene chloride solution. By replacing the grounded plate collector of the conventional electrospinning setup with parallel collector plates placed 1.6 cm apart, the positively charged chitosan fibersbecame alternately attracted to the parallel plates and ended up uniaxially aligned as fiber suspension across the plates. Stability of the chitosan fibers in aqueous, physiological environment was achieved with the use of sodium carbonate to neutralize residual acidity in the chitosan fiber preparation. Schwann cells seeded onto these stabilized aligned chitosan nanofibers aligned uniaxially with the chitosan nanofibers. In addition, by seeding dissociated cells of dorsal root ganglia (DRG, E14/15 rats) onto the uniaxially aligned nanofibers, both neurons and Schwann cells were aligned with uniaxial arrangement of nanofibers, and the Schwann cells showed myelination ofthe axons. A model of the chitosan nerve conduit was constructed with a core nanofiberbundle, and seeding of Schwann cells. Thesein vitro results provide proof-of-principle for pursuing improvement in post-traumatic recovery from nerve injury with use of uniaxially aligned chitosan nanofibers in Schwann cell-seeded nerve guidance channels.
published_or_final_version
Biochemistry
Master
Master of Philosophy
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Bizarria, Maria Trindade Marques. "Montagem de equipamento, desenvolvimento, caracterização e aplicações médico-farmacológicas de nanofibras eletrofiadas à base de blendas de quitosana." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/266809.

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Orientadores: Lucia Helena Innocentini Mei, Marcos Akira D'Ávila
Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Engenharia Química
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Resumo: A obtenção de nanofibras de polímeros biocompatíveis, baseadas em quitosana, bem como a montagem de equipamento capaz de produzi-las, foi o principal objeto deste trabalho. Com este propósito, buscou-se de início reunir os dispositivos eletrônicos e mecânicos indispensáveis à prática da eletrofiação e um equipamento básico, de baixo custo, mas funcional foi construído. Com base na literatura, o ácido acético glacial a 90% em água deionizada foi o solvente utilizado para preparo das soluções de quitosana. Para viabilizar o processo da produção das nanofibras pela técnica da eletrofiação utilizaram-se blendas de soluções de quitosana com soluções de outros polímeros biocompatíveis em vez de soluções de quitosana pura. Assim, blendas de soluções de quitosana com soluções aquosas do poli(óxido de etileno) - PEO , bem como, com soluções aquosas de Poli(álcool vinílico) - PVA, em diversas proporções, foram eletrofiadas. O Poli(óxido de etileno) mostrou superior desempenho, como auxiliar na fiação da quitosana, permitindo a obtenção de fibras com até 80% de quitosana, e com diâmetros inferiores àqueles obtidos com as blendas de soluções de quitosana/PVA. A adição de um eletrólito (NaCl) às soluções blendas de quitosana/PEO proporcionou um processo fácil ininterrupto, sendo assim, buscou-se um melhor entendimento sobre as propriedades das soluções da quitosana e do PEO que norteiam comportamentos mais ou menos favoráveis ao processo da eletrofiação, caracterizando-se essas soluções através de estudos de viscosidade, de medidas de tensão superficial e de condutividade elétrica. A morfologia das fibras obtidas foi caracterizada por microscopia eletrônica de varredura (MEV) e, as propriedades térmicas, das membranas nanoestruturadas resultantes da eletrofiação das soluções de Quitosana/PEO, foram avaliadas por análise termogravimétrica (TGA) e calorimetria diferencial exploratória (DSC). A biocompatibilidade das membranas com teor de quitosana mais elevado (80% quitosana/20% PEO) foi avaliada através de testes de citotoxicidade in vitro, biocompatibilidade in vivo e adesão e crescimento celular in vitro. Adicionalmente, foram conduzidos experimentos visando avaliar o desempenho destas mesmas membranas como carreadoras de fármacos sendo que, a incorporação de nanopartículas de prata (AgNPs), bem como de digluconato de clorexidina apresentaram resultados promissores
Abstract: The development of biocompatible polymer nanofibers based on chitosan and the design and assembly of equipment capable of producing them were the main objectives of this work. For this purpose, the basic electronic and mechanical devices were obtained and a low-cost functional electrospinning setup was built. Based on the literature, glacial acetic acid with concentration of 90% in deionized water was the solvent used to prepare the chitosan solutions. In order to enable the nanofiber production by electrospinning, blends of chitosan solutions with other biocompatible polymers were used instead of pure chitosan solutions. Thus, blends of chitosan solutions with aqueous solutions of poly (ethylene oxide) PEO as well as with aqueous solutions of poly (vinyl alcohol) PVA, in various proportions, were electrospun. The PEO presented superior performance as an aid to obtain chitosan fibers, resulting in fibers with up to 80% of chitosan, and with smaller diameters than those obtained with solutions of blends of chitosan / PVA. The addition of an electrolyte (NaCl) to the chitosan/PEO solution blends has provided an easy and uninterrupted process. Thus, to obtain a better understanding about the properties of chitosan and PEO solutions that lead to more or less favorable behaviors to the electrospinning process, these solutions were characterized by performing viscosity studies and measurements of surface tension and electrical conductivity. The morphology of the fibers was evaluated by scanning electron microscopy (SEM) and the thermal properties of nanostructured membranes resulting from electrospinning of chitosan/PEO solutions were evaluated by thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC).The biocompatibility of the higher-content-chitosan membranes (80%chitosan /20% PEO) was evaluated by tests of in vitro cytotoxicity, in vivo biocompatibility and in vitro cell adhesion and growth. In addition, experiments were conducted to evaluate the performance of the same membrane as a carrier of drugs. In this way, the incorporation of silver nanoparticles (AgNPs) and chlorhexidine digluconate showed promising results
Doutorado
Ciencia e Tecnologia de Materiais
Doutor em Engenharia Química

Book chapters on the topic "Nanofibres of chitosan":

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Gadkari, Rahul, Wazed Ali, Apurba Das, and R. Alagirusamy. "Scope of Electrospun Chitosan Nanofibrous Web for its Potential Application in Water Filtration." In Chitosan, 431–51. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2017. http://dx.doi.org/10.1002/9781119364849.ch16.

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Murali, Vishnu Priya, and Priyadarshan Sundararaju. "Chitosan Nanofibers in Regenerative Medicine." In Advances in Polymer Science, 29–86. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/12_2021_91.

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Ifuku, Shinsuke, Makoto Anraku, and Kazuo Azuma. "Preparation of Chitin Nanofiber and Its Derivatives from Crab Shell and Their Efficient Biological Properties." In Chitosan for Biomaterials III, 301–18. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/12_2021_87.

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Kossovich, L. Y., Y. Salkovskiy, and I. V. Kirillova. "Electrospun Chitosan Nanofiber Materials as Burn Dressing." In IFMBE Proceedings, 1212–14. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-14515-5_307.

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Rošic, R., P. Kocbek, S. Baumgartner, and J. Kristl. "Electrospun Chitosan/Peo Nanofibers and Their Relevance in Biomedical Application." In IFMBE Proceedings, 1296–99. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-23508-5_335.

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Pervez, Md Nahid, George K. Stylios, Yingjie Cai, Shadi Wajih Hasan, Tiziano Zarra, Vincenzo Belgiorno, and Vincenzo Naddeo. "Water-Soluble Chitosan Nanofibrous Membranes for Efficient Dye Removal." In Advances in Science, Technology & Innovation, 213–15. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-00808-5_49.

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Shariatinia, Zahra, and Iraj Kohsari. "Fabrication of Antibacterial Electrospun Chitosan-Polyethylene Oxide Nanocomposite Nanofibrous Mats." In Eco-friendly and Smart Polymer Systems, 19–22. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-45085-4_5.

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Qurashi, Ahsanulhaq. "Chitin and Chitosan Polymer Nanofibrous Membranes and Their Biological Applications." In Handbook of Bioplastics and Biocomposites Engineering Applications, 357–70. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2011. http://dx.doi.org/10.1002/9781118203699.ch13.

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Kurashina, Masashi, Daiki Kato, Haoyuan Li, Keita Shiba, Yuta Morishita, Kazuki Shibata, Ho Hong Quyen, and Mikito Yasuzawa. "Synthesis of N-Methyl-D-Glucamine Modified Chitosan Nanofibers for Boron Adsorption." In Springer Proceedings in Physics, 31–35. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-7153-4_4.

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Sofi, Hasham S., Nisar Ahmad Khan, and Faheem A. Sheikh. "Smart Biomaterials from Electrospun Chitosan Nanofibers by Functionalization and Blending in Biomedical Applications." In Application of Nanotechnology in Biomedical Sciences, 51–73. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-5622-7_4.

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Conference papers on the topic "Nanofibres of chitosan":

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Rijal, Nava P., Udhab Adhikari, and Narayan Bhattarai. "Magnesium Incorporated Polycaprolactone-Based Composite Nanofibers." In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-53090.

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Recent advances in developing composite nanofibers are of great interest for scientific community due to their wide range of potential applications in biomedical engineering such as drug delivery, wound healing, tissue engineering and implant coatings. Here, we present a fabrication of Mg incorporated polycaprolactone/low molecular weight chitosan (PCL/LMW-CS) composite nanofiber via an electrospinning technique. PCL, a synthetic polymer, has good mechanical properties, whereas, chitosan, a natural polymer, has good bio-functional properties and good cell adhesion properties. Furthermore, magnesium is the second most abundant intracellular cation in the body and is important to metabolism. These nanofibers were characterized by using Scanning Electron Microscopy (SEM), ImageJ, and Instron Universal Testing Machine.
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Tayerani, Ehsan, Seyyed Mohammad Ghoreishi, Neda Habibi, Laura Pastorino, and Carmelina Ruggiero. "Electrospun chitosan nanofibers for tissue engineering." In 2014 IEEE 14th International Conference on Nanotechnology (IEEE-NANO). IEEE, 2014. http://dx.doi.org/10.1109/nano.2014.6968179.

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Rupiasih, Ni Nyoman, Ria Yuliani, Dewa Ayu Pranastia, Made Sumadiyasa, Wayan Supardi, I. Made Sukadana, and Maykel Manawan. "PVA/Chitosan Composite Electrospun Nanofiber Membranes for Wound Dressing and Antibacterial Efficacy." In The 4th International Conference on Science and Technology Applications. Switzerland: Trans Tech Publications Ltd, 2023. http://dx.doi.org/10.4028/p-64xk11.

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A Research has been carried out on the manufacture and characterization of Polyvinyl Alcohol (PVA)/Chitosan composite nanofiber membranes using electrospinning technique which addressed for wound dressing and antibacterial efficacy. The electrospun composite nanofiber membranes were made with various volume ratios of PVA:Chitosan, namely 1:9, 2:8, and 3:7, which were named P9K1, P8K2, and P7K3 respectively. The electrospinning was performed at a voltage of 10 kV, the distance between the nozzle tip to the collector was 10 cm, a flow rate of 1 µl/h, at room temperature, a relative humidity (RH) of around 63%, and the spinning time was 3 h. Their physical and chemical were characterized by FTIR, SEM, DMA (dynamic analytical analysis), and antibacterial activity. These characterization results indicated that adding chitosan greatly affects the quality of the nanofiber membranes formed and their potential applications. The addition of chitosan produced nanofiber membranes with a larger diameter, shorter fibers, and more beads and droplets. The functional groups in the nanofiber membranes experienced a wavenumber shifting and increased transmittance which was relatively high compared to pure PVA nanofiber membrane (P10K0). Only the P8K2 met the standard for medical materials, with UTS and PTP of 2.73 MPa and 19.03% respectively. Also, it had antibacterial efficacy against E.coli and S. aureus of 16.90% and 8.87% respectively.
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Mak, Eva Yi-Wah, and Wallace Woon-Fong Leung. "Novel Nanofibrous Scaffold to Improve Wound Healing." In ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-64223.

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An antibacterial and biocompatible scaffold for fibroblasts proliferation based on chitosan has been developed. Chitosan solution is electrospun into uniform fibers of 100–200 nm in diameter that mimic the extracellular matrix of human skin. The fibrous mats are successfully cross-linked to be stable in acidic solution, which can be used to treat acute wounds. The crosslinked fibrous mats display antibacterial properties toward Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli. The mechanical properties of fibrous mats are shown to be comparable to native skin dermis which protects the skin wound.
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Riwu, Yonas Ferdinand, Fames Humala Putra Loi, Ahmad Kusumaatmaja, Roto, and Kuwat Triyana. "Effect of Chitosan concentration and heat treatment on electrospun PVA/Chitosan nanofibers." In TECHNOLOGIES AND MATERIALS FOR RENEWABLE ENERGY, ENVIRONMENT AND SUSTAINABILITY: TMREES. Author(s), 2016. http://dx.doi.org/10.1063/1.4958585.

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Kang, Yun Mi, Jae Hoon Ko, E. Sle Kim, Gyeong Hae Kim, Goh Woon Park, Young Hwan Park, Byoung Hyun Min, Bong Lee, Jae Ho Kim, and Moon Suk Kim. "Electrospun chitosan nanofiber for tissue engineering." In 2010 IEEE 3rd International Nanoelectronics Conference (INEC). IEEE, 2010. http://dx.doi.org/10.1109/inec.2010.5425166.

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Bezir, Nalan Çiçek, Bilal Bozkurt, Atilla Evcin, Burcu Özcan, Esengül Kır, Gökhan Akarca, and Ozan Ceylan. "Enhanced antibacterial activity of silver-doped chitosan nanofibers." In TURKISH PHYSICAL SOCIETY 35TH INTERNATIONAL PHYSICS CONGRESS (TPS35). AIP Publishing, 2019. http://dx.doi.org/10.1063/1.5135401.

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Mahatmanti, F. Widhi, Ella Kusumastuti, and Nanik Wijayati. "Electrospinning of chitosan/PVA nanofibers: Preparation and characterization." In INTERNATIONAL CONFERENCE ON APPLIED COMPUTATIONAL INTELLIGENCE AND ANALYTICS (ACIA-2022). AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0125932.

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Cin, Gunseli Turgut, Seda Demirel Topel, Neslihan Nohut Maslakci, Esin Eren, and Aysegul Uygun Oksuz. "Plasma modified chitosan/N-acetyl-2-pyrazoline derivative nanofibers." In 2015 IEEE International Conference on Plasma Sciences (ICOPS). IEEE, 2015. http://dx.doi.org/10.1109/plasma.2015.7179648.

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Liang, J. I., H. C. Hsu, Y. H. Nien, F. C. Su, H. W. Wu, J. P. Chen, and M. L. Yeh. "Cell response to Electrospun PVA and PVA/Chitosan nanofibers." In 2009 IEEE 35th Annual Northeast Bioengineering Conference. IEEE, 2009. http://dx.doi.org/10.1109/nebc.2009.4967779.

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Reports on the topic "Nanofibres of chitosan":

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Cabrera, Anahi Maldonado, Blayra Maldonado Cabrera, Dalia Isabel Sánchez Machado, and Jaime López Cervantes. Wound healing therapeutic effect of chitosan nanofibers: a systematic review and meta- analysis of animal studies. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, October 2022. http://dx.doi.org/10.37766/inplasy2022.10.0121.

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Abstract:
Review question / Objective: Review question: Does chitosan base nanofibers has significant wound healing therapeutics effects in animal models? A preclinical systematic review of intervention will be carried out to evaluate the therapeutic effects of chitosan nanofibers on animal skin lesions. The PICO (Population, Intervention, Comparator, Outcome) scheme will be used: Intervention: full-thickness skin lesions, and the application of chitosan nanofibers as treatment for animal skin lesions. Regardless of the concentration of chitosan or other added compounds used. Comparison: No intervention, topical placebo agents and standard skin lesions treatments will be included. Outcome: wound healing area, wound closure, type of wound closure (first, second or third intention), healing time, infectious processes (antibacterial/antifungal properties), blood loss (hemostatic properties) and adverse effects.

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