Academic literature on the topic '(Na+,K+)-dependent ATPase'
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Journal articles on the topic "(Na+,K+)-dependent ATPase"
Aizman, R. I., G. Celsi, L. Grahnquist, Z. M. Wang, Y. Finkel, and A. Aperia. "Ontogeny of K+ transport in rat distal colon." American Journal of Physiology-Gastrointestinal and Liver Physiology 271, no. 2 (August 1, 1996): G268—G274. http://dx.doi.org/10.1152/ajpgi.1996.271.2.g268.
Full textBenders, A. A., J. A. Timmermans, A. Oosterhof, H. J. Ter Laak, T. H. M. S. M. van Kuppevelt, R. A. Wevers, and J. H. Veerkamp. "Deficiency of Na+/K+-ATPase and sarcoplasmic reticulum Ca2+-ATPase in skeletal muscle and cultured muscle cells of myotonic dystrophy patients." Biochemical Journal 293, no. 1 (July 1, 1993): 269–74. http://dx.doi.org/10.1042/bj2930269.
Full textMathews, P. M., D. Claeys, F. Jaisser, K. Geering, J. D. Horisberger, J. P. Kraehenbuhl, and B. C. Rossier. "Primary structure and functional expression of the mouse and frog alpha-subunit of the gastric H(+)-K(+)-ATPase." American Journal of Physiology-Cell Physiology 268, no. 5 (May 1, 1995): C1207—C1214. http://dx.doi.org/10.1152/ajpcell.1995.268.5.c1207.
Full textMissiaen, L., F. Wuytack, H. De Smedt, M. Vrolix, and R. Casteels. "AlF4- reversibly inhibits ‘P’-type cation-transport ATPases, possibly by interacting with the phosphate-binding site of the ATPase." Biochemical Journal 253, no. 3 (August 1, 1988): 827–33. http://dx.doi.org/10.1042/bj2530827.
Full textAsano, Shinji, Satomi Hoshina, Yumi Nakaie, Toshiyuki Watanabe, Michihiko Sato, Yuichi Suzuki, and Noriaki Takeguchi. "Functional expression of putative H+-K+-ATPase from guinea pig distal colon." American Journal of Physiology-Cell Physiology 275, no. 3 (September 1, 1998): C669—C674. http://dx.doi.org/10.1152/ajpcell.1998.275.3.c669.
Full textKraut, J. A., F. Starr, G. Sachs, and M. Reuben. "Expression of gastric and colonic H(+)-K(+)-ATPase in the rat kidney." American Journal of Physiology-Renal Physiology 268, no. 4 (April 1, 1995): F581—F587. http://dx.doi.org/10.1152/ajprenal.1995.268.4.f581.
Full textCrambert, Gilles, Ciming Li, Dirk Claeys, and Käthi Geering. "FXYD3 (Mat-8), a New Regulator of Na,K-ATPase." Molecular Biology of the Cell 16, no. 5 (May 2005): 2363–71. http://dx.doi.org/10.1091/mbc.e04-10-0878.
Full textOno, S., J. Guntupalli, and T. D. DuBose. "Role of H(+)-K(+)-ATPase in pHi regulation in inner medullary collecting duct cells in culture." American Journal of Physiology-Renal Physiology 270, no. 5 (May 1, 1996): F852—F861. http://dx.doi.org/10.1152/ajprenal.1996.270.5.f852.
Full textVujisic, Ljubica, Danijela Krstic, and Jovan Vucetic. "Chemical aspect of the influence of cobalt ions on atpase activity." Journal of the Serbian Chemical Society 65, no. 7 (2000): 507–15. http://dx.doi.org/10.2298/jsc0007507v.
Full textReinhardt, J., M. Kosch, M. Lerner, H. Bertram, D. Lemke, and H. Oberleithner. "Stimulation of protein kinase C pathway mediates endocytosis of human nongastric H+-K+-ATPase, ATP1AL1." American Journal of Physiology-Renal Physiology 283, no. 2 (August 1, 2002): F335—F343. http://dx.doi.org/10.1152/ajprenal.00226.2001.
Full textDissertations / Theses on the topic "(Na+,K+)-dependent ATPase"
Hao, Jingping. "The electrical properties of Bufo marinus Na⁺, K⁺-ATPase." Ohio : Ohio University, 2009. http://www.ohiolink.edu/etd/view.cgi?ohiou1258151062.
Full textCheng, Sam Xian Jun. "Functional significance of phosphorylation of rat renal Na+,K+-ATPase by PKA and PKC /." Stockholm, 1998. http://diss.kib.ki.se/1998/91-628-2971-8.
Full textNguyen, Khoa Thuy Diem. "Energy metabolism in the brain and rapid distribution of glutamate transporter GLAST in astrocytes." Thesis, The University of Sydney, 2008. http://hdl.handle.net/2123/3996.
Full textNguyen, Khoa Thuy Diem. "Energy metabolism in the brain and rapid distribution of glutamate transporter GLAST in astrocytes." University of Sydney, 2008. http://hdl.handle.net/2123/3996.
Full textGlutamate transporters play a role in removing extracellular excitatory neurotransmitter, L-glutamate into the cells. The rate of the uptake depends on the density of the transporters at the membrane. Some studies claimed that glutamate transporters could transit between the cytoplasm and the membrane on a time-scale of minutes. The present study examined the distribution of glutamate transporter GLAST predominantly expressed in rat cortical cultured astrocytes between the membrane and the cytoplasm by using deconvolution microscopy and then analyzing the images. The regulation of the distribution of GLAST was studied in the presence of glutamate transporter substrate (D-aspartate), purinergic receptor activators (α,β-methylene ATP, adenosine), neuroleptic drugs (clozapine, haloperidol), ammonia (hyperammonia) and Na+/K+-ATPase inhibitors (ouabain, digoxin and FCCP). It was demonstrated that the translocation of GLAST towards the plasma membrane was induced by D-aspartate, α,β-methylene ATP, adenosine, clozapine and ammonia (at 100 μM and very high concentrations of 10 mM). However, the inhibition of Na+/K+-ATPase activity had an opposite effect, resulting in redistribution of GLAST away from the membrane. It has previously been claimed that the membrane-cytoplasm trafficking of GLAST was regulated by phosphorylation catalysed by protein kinase C delta (PKC-delta). Involvement of this mechanism has, however, been put to doubt when rottlerin, a PKC-delta inhibitor, used to test the hypothesis showed to inhibit Na+/K+-ATPase-mediated uptake of Rb+, suggesting that rottlerin influenced the activity of Na+/K+-ATPase. As Na+/K+-ATPase converts ATP to energy and pumps Na+, K+ ions, thus helping to maintain normal electrochemical and ionic gradients across the cell membrane. Its inhibition also reduced D-aspartate transport and could impact on the cytoplasm-to-membrane traffic of GLAST molecules. Furthermore, rottlerin decreased the activity of Na+/K+-ATPase by acting as a mitochondrial inhibitor. The present study has focused on the inhibition of Na+/K+-ATPase activity by rottlerin, ouabain and digoxin in homogenates prepared from rat kidney and cultured astrocytes. The activity of Na+/K+-ATPase was measured by the absorption of inorganic phosphate product generated from the hydrolysis of ATP and the fluorescent transition of the dye RH421 induced by the movement of Na+/K+-ATPase. This approach has a potential to test whether the rottlerin effect on Na+/K+-ATPase is a direct inhibition of the enzyme activity. Rottlerin has been found to block the activity of Na+/K+-ATPase in a dose-dependent manner in both rat kidney and astrocyte homogenates. Therefore, rottlerin inhibited the activity of Na+/K+-ATPase directly in a cell-free preparation, thus strongly indicating that the effect was direct on the enzyme. In parallel experiments, ouabain and digoxin produced similar inhibitions of Na+/K+-ATPase activity in rat kidney while digoxin blocked the activity of Na+/K+-ATPase to a greater extent than ouabain in rat cortical cultured astrocytes. In a separate set of experiments, Na+/K+-ATPase in the astrocytic membrane was found to be unsaturated in E1(Na+)3 conformation in the presence of Na+ ions and this could explain the differences between the effects of digoxin and ouabain on the activity of Na+/K+-ATPase in rat astrocytes. In addition, it was found that at low concentrations of rottlerin, the activity of Na+/K+-ATPase was increased rather than inhibited. This effect was further investigated by studying rottlerin interactions with membrane lipids. The activity of Na+/K+-ATPase has been reported to be regulated by membrane lipids. The enzyme activity can be enhanced by increasing fluidity of the lipid membrane. I have, therefore, proposed that rottlerin binds to the membrane lipids and the effects of rottlerin on Na+/K+-ATPase are mediated by changes in the properties (fluidity) of the membrane. The hypothesis was tested by comparing rottlerin and a detergent, DOC (sodium deoxycholate), for their binding to the lipids by using a DMPC (1,2-Dimyristoyl-sn-Glycero-3-Phosphocholine) monolayer technique. DOC has been shown to both increase and inhibit activity of Na+/K+-ATPase in a manner similar to that displayed by rottlerin. The effects of rottlerin and DOC on the DMPC monolayers were studied by measuring the surface pressure of DMPC monolayers and surface area per DMPC molecule. I established that both rottlerin and DOC decreased the surface pressure of DMPC monolayers and increased the surface area per DMPC molecule. This indicates that both rottlerin and DOC penetrated into the DMPC monolayers. If rottlerin can interact with the lipids, changes in fluidity of the lipid membrane cannot be ruled out and should be considered as a possible factor contributing to the effects of rottlerin on the activity of Na+/K+-ATPase. Overall, the study demonstrates that rottlerin is not only a PKC-delta inhibitor but can have additional effects, both on the enzyme activities (Na+/K+-ATPase) and/or on lipid-containing biological structures such as membranes. The findings have implication not only for studies where rottlerin was used as a supposedly specific PKC-delta inhibitor but also for mechanisms of its toxicity.
Kuznetsova, Irina [Verfasser]. "Inhibition of the influenza A virus-induced, tubulin-dependent apical mislocalization of the Na+,K+-ATPase in infected cells: Improving vectorial water transport and pulmonary edema clearance / Irina Kuznetsova." Gießen : Universitätsbibliothek, 2020. http://d-nb.info/1216143633/34.
Full textSchneeberger, Anne. "Ionenbindung an die Na, K-ATPase." [S.l. : s.n.], 2000. http://deposit.ddb.de/cgi-bin/dokserv?idn=959955968.
Full textLiang, Man. "Na/K ATPase : signaling versus pumping." Toledo, Ohio : University of Toledo, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=mco1173803261.
Full text"In partial fulfillment of the requirements for the degree of Doctor of Philosophy in Biomedical Sciences." Major advisor: Zi-Jian Xie. Includes abstract. Document formatted into pages: iii, 156 p. Title from title page of PDF document. Bibliography: pages 64-67, 97-100, 116-117, 125-155.
Tian, Jiang. "Na/K-ATPase : a signaling receptor." Connect to Online Resource-OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=mco1175177603.
Full text"In partial fulfillment of the requirements for the degree of Doctor of Philosophy in Biomedical Sciences." Major advisor: Zi-Jian Xie. Includes abstract. Title from title page of PDF document. Bibliography: pages 64-70, 104-108, 121-158.
Aizman, Oleg. "Novel aspects of Na⁺,K⁺-ATPase /." Stockholm, 2002. http://diss.kib.ki.se/2002/91-7349-311-2.
Full textCarradus, Maria. "Structural studies of Na'+K'+-ATPase." Thesis, Imperial College London, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342323.
Full textBooks on the topic "(Na+,K+)-dependent ATPase"
Chakraborti, Sajal, and Naranjan S. Dhalla, eds. Regulation of Membrane Na+-K+ ATPase. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-24750-2.
Full textHorisberger, Jean-Daniel. The Na,K-ATPase: Structure-function relationship. Austin: R.G. Landes, 1994.
Find full textInternational Conference on the Na/K-ATPase and Related ATPases (9th 1999 Sapporo, Japan). Na/K-ATPase and related ATPases: Proceedings of the 9th International Conference on the Na/K-ATPase and Related ATPases, Sapporo, Japan, 18-23 August 1999. Edited by Kaya Shunji and Taniguchi Kazuya 1966-. Amsterdam: Elsevier, 2000.
Find full textJ, Shearer M., and Seghatchian M. J, eds. Vitamin K and vitamin K-dependent proteins: Analytical, physiological, and clinical aspects. Boca Raton, Fla: CRC Press, 1993.
Find full textGaretz, Susan Lynn. Variation in expression of Na+K+ATPase ł and ø subunit mRNAs in rat tissues and nervous system cell lines. [New Haven: s.n.], 1989.
Find full textInternational, Conference on Na K.-ATPase. The sodium pump: Proceedings of the Fourth International Conference on Na, K-ATPase held at the Physiological Laboratory, Cambridge, in August 1984. Cambridge: Company of Biologists, 1985.
Find full textIan, Glynn, Ellory J. C, and Company of Biologists, eds. The sodium pump: Proceedings of the Fourth International Conference on Na, K-ATPase, held at the Physiological Laboratory, Cambridge, in August 1984. Cambridge, U.K: Company of Biologists, 1985.
Find full textYasunobu, Suketa, and Excerpta Medica (Firm), eds. Control and diseases of sodium dependent transport proteins and ion channels: Proceedings of the First International Conference held in Shizuoka, Japan, 24-28th August 1999. Amsterdam: Elsevier, 2000.
Find full textDhalla, Naranjan S., and Sajal Chakraborti. Regulation of Membrane Na+-K+ ATPase. Springer, 2015.
Find full textChakraborti, Sajal, and Naranjan S. Dhalla. Regulation of Membrane Na+-K+ ATPase. Springer, 2015.
Find full textBook chapters on the topic "(Na+,K+)-dependent ATPase"
Spieker, C., K. H. Rahn, and W. Zidek. "Age-dependent secretion of a Na+ K+ ATPase inhibitor in spontaneously hypertensive rats." In Arteriosklerotische Gefäßerkrankungen, 410–16. Wiesbaden: Vieweg+Teubner Verlag, 1992. http://dx.doi.org/10.1007/978-3-663-19646-4_47.
Full textObradovic, Milan, Julijana Stanimirovic, Anastasija Panic, Bozidarka Zaric, and Esma R. Isenovic. "Na+/K+-ATPase." In Encyclopedia of Signaling Molecules, 3338–43. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_101543.
Full textObradovic, Milan, Julijana Stanimirovic, Anastasija Panic, Bozidarka Zaric, and Esma R. Isenovic. "Na +/K+-ATPase." In Encyclopedia of Signaling Molecules, 1–6. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4614-6438-9_101543-1.
Full textScheiner-Bobis, G. "Na+/K+-ATPase." In Encyclopedia of Molecular Pharmacology, 1–10. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-21573-6_267-1.
Full textScheiner-Bobis, G. "Na+/K+-ATPase." In Encyclopedia of Molecular Pharmacology, 1062–71. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-57401-7_267.
Full textLee, Chin Ok, and David C. Gadsby. "PKA Activation in Cardiac Myocytes Affects the Voltage Dependence of Na-K ATPase Pump and Na-Ca Exchange Currents Differently." In The Primo Vascular System, 271–83. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4614-0601-3_37.
Full textDelamere, Nicholas A., and Shigeo Tamiya. "Lens Na+, K+-ATPase." In Ocular Transporters In Ophthalmic Diseases And Drug Delivery, 111–23. Totowa, NJ: Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-375-2_6.
Full textde Pont, Jan Joep H. H. M., Jan B. Koenderink, Herman G. P. Swarts, and Peter H. G. M. Willems. "Structure-Activity Relationships of Na,K-ATPase and H,K-ATPase." In Mechanisms and Consequences of Proton Transport, 71–82. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0971-4_7.
Full textSachs, George, and Björn Wallmark. "The gastric H, K ATPase." In Proton Pump Inhibitors, 23–45. Basel: Birkhäuser Basel, 1999. http://dx.doi.org/10.1007/978-3-0348-8795-3_2.
Full textChakraborti, Sajal, Sayed Modinur Rahaman, Md Nur Alam, Amritlal Mandal, Biswarup Ghosh, Kuntal Dey, and Tapati Chakraborti. "Na+/K+-ATPase: A Perspective." In Regulation of Membrane Na+-K+ ATPase, 3–30. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-24750-2_1.
Full textConference papers on the topic "(Na+,K+)-dependent ATPase"
Grzesik, Benno, Ramona Ruhl, Nieves Gabrielli, Werner Seeger, Wolfgang Kummer, Uwe Pfeil, and Istvan Vadasz. "Intermedin Enhances Alveolar Edema Clearance By Promoting Na,K-ATPase Exocytosis In A Protein Kinase A-Dependent But CAMP-Independent Manner." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a3521.
Full textGusarova, GA, LA Dada, A. Briva, H. Trejo, and JI Sznajder. "Hypoxia Leads to Ca2+/Calmodulin-Dependent Kinase Kinase β (CaMKKβ) Activation/AMPK Phosphorylation, Na,K-ATPase Endocytosis and Impaired Alveolar Epithelial Reabsorbtion." In American Thoracic Society 2009 International Conference, May 15-20, 2009 • San Diego, California. American Thoracic Society, 2009. http://dx.doi.org/10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a1927.
Full textHack, N., J. M. Wilkinson, and N. Crawford. "A MONOCLONAL ANTIBODY (PL/IM 430) THAT BLOCKS THE ACTIVE TRANSL0CATI0N OF Ca2+ INTO HUMAN PLATELET INTRACELLULAR MEMBRANE (ER) VESICLES." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644678.
Full textFujimoto, T., B. Djuricic, K. Tanoue, Y. Fukushima, and H. Yamazaki. "CHANGES IN ENZYMATIC ACTIVITIES IN BRAIN CAPILLARY ENDOTHELIAL CELLS INJURED BY PLATELET AGGREGATION IN VIVO." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643368.
Full textLestari, Silvia W., Aucky Hinting, Hamdani Lunardi, Debby Aditya, Dessy Noor Miati, and Meidika Dara Rizki. "Sperm Na+,K+-ATPase and dynein ATPase activity: A study of embryo development in in vitro fertilization (IVF)." In SECOND INTERNATIONAL CONFERENCE OF MATHEMATICS (SICME2019). Author(s), 2019. http://dx.doi.org/10.1063/1.5096752.
Full textOnken, Horst. "V-ATPase and Na+/K+-ATPase energize postprandial fluid absorption from the isolated midgut of female yellow fever mosquitoes (Aedes aegypti)." In 2016 International Congress of Entomology. Entomological Society of America, 2016. http://dx.doi.org/10.1603/ice.2016.93236.
Full textKrastev, Dragomir, Shudong Li, Yilun Sun, Yves Pommier, Kristijan Ramadan, and Christopher J. Lord. "Abstract P057: The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin." In Abstracts: AACR-NCI-EORTC Virtual International Conference on Molecular Targets and Cancer Therapeutics; October 7-10, 2021. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1535-7163.targ-21-p057.
Full textYang, Liqun, Olga Lopina, Daniel McStay, A. A. Boldyrev, Alan J. Rogers, and Peter J. Quinn. "Time-resolved phosphorescence measurement of conformational transitions in cation transport Na+, K+-ATPase." In OE/LASE'93: Optics, Electro-Optics, & Laser Applications in Science& Engineering, edited by Laurence A. Nafie and Henry H. Mantsch. SPIE, 1993. http://dx.doi.org/10.1117/12.145246.
Full textLi, Zhiqin, Alisa Litan, Seung Joon Lee, Bruce Graves, Sonali P. Barwe, and Sigrid A. Langhans. "Abstract 707: Distinct roles of Na,K-ATPase function and expression in medulloblastoma." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-707.
Full textLestari, Silvia W., Manggiasih D. Larasati, Asmarinah, and Indra G. Mansur. "Sperm Na+, K+-ATPase and Ca2+-ATPase activity: A preliminary study of comparison of swim up and density gradient centrifugation methods for sperm preparation." In 2ND BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, AND MEDICAL DEVICES: Proceedings of the International Symposium of Biomedical Engineering (ISBE) 2017. Author(s), 2018. http://dx.doi.org/10.1063/1.5023963.
Full textReports on the topic "(Na+,K+)-dependent ATPase"
Colton, Joel S., Sara C. Gilman, and Carol A. Colton. Effect of the Thiol-Oxidizing Agent, Diamide, on Cerebral Cortical Na(+) -K(+) ATPase. Fort Belvoir, VA: Defense Technical Information Center, September 1988. http://dx.doi.org/10.21236/ada205311.
Full textAubert, B. Measurement of Time-Dependent CP-Violating Asymmetries in B0 ->K*0 gamma (K*0->K0{sub S} pi0) Decays. Office of Scientific and Technical Information (OSTI), June 2004. http://dx.doi.org/10.2172/826956.
Full textAubert, B. Measurements of Branching Fractions and Time-Dependent CP-Violating Asymmetries in B to eta' K Decays. Office of Scientific and Technical Information (OSTI), February 2005. http://dx.doi.org/10.2172/839753.
Full textGronau, M. Interpreting the Time-Dependent CP Asymmetry in B{sup 0} {yields} {pi}{sup 0} K{sub S}. Office of Scientific and Technical Information (OSTI), November 2003. http://dx.doi.org/10.2172/826518.
Full textIlic, J. Time-dependent Dalitz-Plot Analysis of the Charmless Decay B^0 -> K^0S Pi Pi- at BABAR. Office of Scientific and Technical Information (OSTI), October 2009. http://dx.doi.org/10.2172/968531.
Full textPalombo, F. Measurement of Time-Dependent CP-Violating Asymmetries in B{sup 0} Meson Decays to eta' K{sup 0}. Office of Scientific and Technical Information (OSTI), August 2004. http://dx.doi.org/10.2172/829746.
Full textAubert, B. Ambiguity-Free Measurement of cos2beta: Time-Intergrated and Time-Dependent Angular Analyses of B to J/psi K pi. Office of Scientific and Technical Information (OSTI), November 2004. http://dx.doi.org/10.2172/839607.
Full textT'Jampens, Stephane. Study of CP Symmetry Violation in the Charmonium-K*(892) Channel By a Complete Time Dependent Angular Analysis (BaBar Experiment). Office of Scientific and Technical Information (OSTI), September 2006. http://dx.doi.org/10.2172/891862.
Full textJoseph Marion Tuggle IV. Radiative B Meson Decay as a Probe of Physics Beyond the Standard Model: Time-Dependent CP Violation in B0 → K0S π0 γ and the B → Φ K γ Branching Fraction. Office of Scientific and Technical Information (OSTI), January 2009. http://dx.doi.org/10.2172/946450.
Full textBiassoni, Pietro. Measurements of Time-Dependent CP-Asymmetry Parameters in B Meson Decays to η' K0 and of Branching Fractions of SU(3) Related Modes with BaBar Experiment at SLAC. Office of Scientific and Technical Information (OSTI), January 2009. http://dx.doi.org/10.2172/946451.
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