Journal articles on the topic 'N-desmethyl imatinib'
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Wang, Zhe, Li Wang, Meng-ming Xia, Wei Sun, Cheng-ke Huang, Xiao Cui, Guo-xin Hu, Qing-quan Lian, and Zeng-shou Wang. "Pharmacokinetics Interaction between Imatinib and Genistein in Rats." BioMed Research International 2015 (2015): 1–7. http://dx.doi.org/10.1155/2015/368976.
Full textLiu, Xian-yun, Tao Xu, Wan-shu Li, Jun Luo, Pei-wu Geng, Li Wang, Meng-ming Xia, Meng-chun Chen, Lei Yu, and Guo-xin Hu. "The Effect of Apigenin on Pharmacokinetics of Imatinib and Its Metabolite N-Desmethyl Imatinib in Rats." BioMed Research International 2013 (2013): 1–6. http://dx.doi.org/10.1155/2013/789184.
Full textBornhäuser, Martin, Stefan Pursche, Malte Bonin, Jens Freiberg-Richter, Andreas Jenke, Thomas Illmer, Gerhard Ehninger, and Eberhard Schleyer. "Elimination of Imatinib Mesylate and Its Metabolite N-Desmethyl-Imatinib." Journal of Clinical Oncology 23, no. 16 (June 1, 2005): 3855–56. http://dx.doi.org/10.1200/jco.2005.05.246.
Full textSchleyer, E., O. G. Ottmann, T. Illmer, S. Pursche, T. Leopold, M. Bonin, J. Freiberg-Richter, et al. "Pharmacokinetics of Imatinib and its Main Metabolite N-desmethyl-imatinib." TumorDiagnostik & Therapie 25, no. 04 (August 2004): 192–96. http://dx.doi.org/10.1055/s-2004-813484.
Full textKhan, Muhammad Suleman, Daniel T. Barratt, and Andrew A. Somogyi. "Impact ofCYP2C8*3polymorphism onin vitrometabolism of imatinib to N-desmethyl imatinib." Xenobiotica 46, no. 3 (July 10, 2015): 278–87. http://dx.doi.org/10.3109/00498254.2015.1060649.
Full textZhang, Y., S. Qiang, Z. Yu, W. Zhang, Z. Xu, L. Yang, A. Wen, and T. Hang. "LC-MS-MS Determination of Imatinib and N-Desmethyl Imatinib in Human Plasma." Journal of Chromatographic Science 52, no. 4 (April 10, 2013): 344–50. http://dx.doi.org/10.1093/chromsci/bmt037.
Full textRao, Zhi, Bo-xia Li, Yong-Wen Jin, Wen-Kou, Yan-rong Ma, Guo-qiang Zhang, Fan Zhang, Yan Zhou, and Xin-an Wu. "Simultaneous Determination of Imatinib and N-Desmethyl Imatinib in Rat Plasma and Tissues Using LC-MS/MS." Current Pharmaceutical Analysis 15, no. 2 (January 4, 2019): 121–29. http://dx.doi.org/10.2174/1573412913666170821124952.
Full textMlejnek, Petr, Petr Dolezel, Edgar Faber, and Petr Kosztyu. "Interactions of N-desmethyl imatinib, an active metabolite of imatinib, with P-glycoprotein in human leukemia cells." Annals of Hematology 90, no. 7 (January 12, 2011): 837–42. http://dx.doi.org/10.1007/s00277-010-1142-7.
Full textSolassol, I., F. Bressolle, L. Philibert, V. Charasson, C. Astre, and F. Pinguet. "Liquid Chromatography‐Electrospray Mass Spectrometry Determination of Imatinib and Its Main Metabolite, N‐Desmethyl‐Imatinib in Human Plasma." Journal of Liquid Chromatography & Related Technologies 29, no. 20 (December 2006): 2957–74. http://dx.doi.org/10.1080/10826070600981058.
Full textZhang, Mei, Grant A. Moore, Liam J. Fernyhough, Murray L. Barclay, and Evan J. Begg. "Determination of imatinib and its active metabolite N-desmethyl imatinib in human plasma by liquid chromatography/tandem mass spectrometry." Analytical and Bioanalytical Chemistry 404, no. 6-7 (August 3, 2012): 2091–96. http://dx.doi.org/10.1007/s00216-012-6284-0.
Full textMarangon, Elena, Marco Citterio, Federica Sala, Elena Barisone, Alma Augusta Lippi, Carmelo Rizzari, Andrea Biondi, Maurizio D’Incalci, and Massimo Zucchetti. "Pharmacokinetic profile of imatinib mesylate and N-desmethyl-imatinib (CGP 74588) in children with newly diagnosed Ph+ acute leukemias." Cancer Chemotherapy and Pharmacology 63, no. 3 (June 3, 2008): 563–66. http://dx.doi.org/10.1007/s00280-008-0764-0.
Full textArellano, Cécile, Peggy Gandia, Thierry Lafont, Rutchanna Jongejan, and Etienne Chatelut. "Determination of unbound fraction of imatinib and N-desmethyl imatinib, validation of an UPLC–MS/MS assay and ultrafiltration method." Journal of Chromatography B 907 (October 2012): 94–100. http://dx.doi.org/10.1016/j.jchromb.2012.09.007.
Full textGandia, Peggy, Cécile Arellano, Thierry Lafont, Françoise Huguet, Laurence Malard, and Etienne Chatelut. "Should therapeutic drug monitoring of the unbound fraction of imatinib and its main active metabolite N-desmethyl-imatinib be developed?" Cancer Chemotherapy and Pharmacology 71, no. 2 (November 27, 2012): 531–36. http://dx.doi.org/10.1007/s00280-012-2035-3.
Full textMokosch, Annika S., Stefanie Gerbig, Christoph G. Grevelding, Simone Haeberlein, and Bernhard Spengler. "High-resolution AP-SMALDI MSI as a tool for drug imaging in Schistosoma mansoni." Analytical and Bioanalytical Chemistry 413, no. 10 (March 15, 2021): 2755–66. http://dx.doi.org/10.1007/s00216-021-03230-w.
Full textTan, Ka Liong, Ravindran Ankathil, and Siew Hua Gan. "Method development and validation for the simultaneous determination of imatinib mesylate and N-desmethyl imatinib using rapid resolution high performance liquid chromatography coupled with UV-detection." Journal of Chromatography B 879, no. 30 (November 2011): 3583–91. http://dx.doi.org/10.1016/j.jchromb.2011.09.048.
Full textBauer, Sebastian, Ralf A. Hilger, Florian Grabellus, James Nagarajah, Mathias Hoiczyk, Annette Reichardt, Marit Ahrens, et al. "Phase I trial of panobinostat (P) and imatinib (IM) in patients with treatment-refractory gastrointestinal stromal tumors (GIST)." Journal of Clinical Oncology 30, no. 15_suppl (May 20, 2012): 10032. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.10032.
Full textDarweesh, Ruba S., Tamam El-Elimat, Aref Zayed, Tareq N. Khamis, Wahby M. Babaresh, Tawfiq Arafat, and Ahmed H. Al Sharie. "The effect of grape seed and green tea extracts on the pharmacokinetics of imatinib and its main metabolite, N-desmethyl imatinib, in rats." BMC Pharmacology and Toxicology 21, no. 1 (November 16, 2020). http://dx.doi.org/10.1186/s40360-020-00456-9.
Full textSabri, Alaa, Mervat M. Omran, S. Abdel Azim, Raafat Abdelfattah, Rasha Mahmoud Allam, and Samia A. Shouman. "A Study to Explore the Role of IDH1 (R132) Mutation on Imatinib Toxicity and Effect of ABCG2/OCT1 Expression on N-Desmethyl Imatinib Plasma Level in Egyptian Chronic Myeloid Leukemia Patients." Drug Research, January 11, 2023. http://dx.doi.org/10.1055/a-1924-7746.
Full textRahimi Kakavandi, Nader, Tayebeh Asadi, Behrouz Jannat, Khosrou Abdi, Mahmoud Ghazi‐Khansari, Hossein Shahali, and Karim Naraki. "Method development for determination of imatinib and its major metabolite, N ‐desmethyl imatinib, in biological and environmental samples by SA–SHS–LPME and HPLC." Biomedical Chromatography 35, no. 7 (February 25, 2021). http://dx.doi.org/10.1002/bmc.5088.
Full textMorawietz, Carolin M., Hicham Houhou, Oliver Puckelwaldt, Laura Hehr, Domenic Dreisbach, Annika Mokosch, Elke Roeb, Martin Roderfeld, Bernhard Spengler, and Simone Haeberlein. "Targeting Kinases in Fasciola hepatica: Anthelminthic Effects and Tissue Distribution of Selected Kinase Inhibitors." Frontiers in Veterinary Science 7 (December 21, 2020). http://dx.doi.org/10.3389/fvets.2020.611270.
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