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Duchateau, Marie-Emmanuelle. "La personnalité et l'identité des divinités polythéistes d'Europos-Doura des successeurs d'Alexandre à l'attaque Sassanide (~301 av. N. È-256 de N. È. )." Paris 1, 2009. http://www.theses.fr/2009PA010648.
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Cette thèse porte sur l'étude de l'évolution de la personnalité et de l'identité des divinités polythéistes d'Europos-Doura, depuis sa création vers 300 av. N. è. , a sa chute, en 256 de n. E. , à la lumière du renouvellement des données archéologiques actuelles. Nous disposons pour cela d'une petite centaine d''inscriptions grecques et sémitiques, de sculptures et de peintures majoritairement d'époque romaine. Notre démarche est comparatiste et philologique, permettant de réévaluer les différentes origines des divinités et leur personnalité propre à Europos-Doura, seule cité de cette époque -mis à part Hatra- à avoir accueilli trois civilisations différentes: grecque, parthomésopotamienne et romaine. L'enjeu de ce travail est de connaître les raisons pour lesquelles telle divinité indigène a été rapprochée de telle divinité grecque, l'identité d'un dieu n'étant jamais fixée. L'interaction culturelle entre des habitants d'origine différente au sein même de la cité influe également sur les choix d'une interprétation entre une divinité et une autre. Un dieu grec est-il honoré pour ses aspects grecs ou pour ceux du dieu avec qui il est assimilé? Quel est l'impact réel d'une interpretatio graeca ou romana sur les cultes indigènes? Nous cherchons donc à analyser tous les facteurs susceptibles d'être à l'origine d'un changement dans l'identité de telle ou telle divinité et à savoir si un facteur type provoque un changement type. Cela nous permet ainsi de discerner, aux différentes époques de la cité, les tendances culturelles propres à Europos-Doura, -originalité, conformisme ou les deux ?- et leur relation avec les tendances religieuses directrices de ces époques.
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Ferreira, Ana Carolina Franco. "Avaliação das alterações causadas pelo câncer sobre a produção de melatonina na glândula pineal." Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/42/42134/tde-30012008-123952/.
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O objetivo desse trabalho foi estudar os mecanismos que alteram a produção de melatonina na glândula pineal durante o processo de caquexia associada ao câncer e o papel de citocinas neste contexto. Os resultados mostraram um aumento da produção de melatonina no grupo inoculado com o Tumor de Walker 256 (GT) junto com uma maior atividade e expressão gênica da enzima AA-NAT, principal enzima reguladora da síntese de melatonina. O estudo in vitro mostrou que a glândula do GT produziu menos melatonina que a glândula do grupo controle (GC) após estimulação com noradrenalina (NOR). Além disso, o TNF-a foi capaz de modular a síntese de melatonina em cultura, promovendo um efeito estimulatório 2h após o inicio da estimulação com NOR, e um inibitório 4h após essa estimulação. Dessa forma, os resultados indicam que produtos na circulação do rato do GT estão envolvidos na modulação encontrada in vivo e que o TNFa- é um forte candidato a participar dessa modulação promovida pelo estabelecimento da síndrome da caquexia sobre a produção de melatonina na glândula pineal.The purpose of this work was to investigate the mechanisms that modify melatonin synthesis in pineal gland during cancer related cachexia and the involvement of cytokines in this context. The results showed an increment of melatonin production in the group inoculated with Walker 256 Tumor (GT) together with a higher activity and gene expression of AA-NAT enzyme, main enzyme that regulates melatonin synthesis. The in vitro study showed that glands from GT produced less melatonin than glands of the control group (GC) after noradrenalin (NOR) stimulation. Besides, TNF-a was capable to modulate melatonin synthesis in pineal gland culture, promoting a stimulatory effect 2 hours after NOR stimulation and an inhibitory effect 4 hours after this stimulation. Therefore, the results indicate that products from tumor bearing rat\'s circulation are probably involved in the modulation found in vivo and that TNF-a is a strong candidate to participate in cachexia-related modulation of melatonin production in pineal gland.
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Kuczek, Agnieszka. "Wpływ benzoannulacji na równowagi tautometryczne w roztworach pochodnych N-salicylidenoanilin i ich orto-COX pochodnych (X = NH2, CH3, OCH3)." Rozprawa doktorska, [Nakł.aut.], 2008. http://dlibra.utp.edu.pl/Content/256.
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Oliveira, Magali Glaucia Fávaro de. "Usurpação estatal da autonomia da mulher e/ou efetivação do direito fundamental à igualdade de gêneros? Um estudo bourdieusiano das modificações feitas à Lei Maria da Penha pela ação direta de inconstitucionalidade n° 4424." Faculdade de Direito de Vitoria, 2013. http://191.252.194.60:8080/handle/fdv/256.
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Esta pesquisa tem por escopo central estudar as modificações advindas da ADI 4424 e suas implicações na Lei Maria da Penha. Desta forma, o presente estudo intenciona verificar se o novo posicionamento do STF é necessário para a efetivação do direito fundamental à igualdade de gêneros, ante o machismo arraigado na sociedade brasileira ou se é uma usurpação da autonomia da mulher e seu direito de escolha? Como objetivo final, pretende-se demonstrar que a queixa é um forte capital simbólico na mão das mulheres e que a impossibilidade de retratação da representação feita contra o companheiro, talvez, sob a ótica da vítima, não seja benéfica para a supressão da violência doméstica, até porque, é por meio dela que a mulher tem tentado sucumbir a sua hipossuficiência perante o homem ou colocando-se em igual patamar ao dele. O método utilizado é o fenomenológico. Para tanto, utiliza-se a pesquisa bibliográfica, documental e de campo, coletando-se os dados por meio de entrevistas, com roteiro semiestruturado, bem como por meio de trabalho de campo observacional na Vara Especializada em Violência Doméstica e Familiar contra a Mulher de Vila Velha/ES. A pesquisa se divide em quatro capítulos. O primeiro versa acerca da tramitação, procedência, efeitos e argumentos utilizados pelo proponente na ADI 4424 e a fundamentação do voto de cada Ministro em seu julgamento. No segundo, analisa-se, a partir da teoria de Pierre Bourdieu, a questão de gênero como relação entre dominadores e dominados e os efeitos dessas construções. No terceiro capítulo, verificar-se-á a dominação masculina na sociedade brasileira, perfazendo uma breve passagem histórica da mulher na legislação, bem como expondo dados estatísticos, analisando algumas causas influenciadoras que levam os homens a agredir, bem sopesando acerca da luta existente entre a mulher e a queixa. O último capítulo apresenta entrevistas com algumas mulheres que foram impedidas de se retratarem da representação feita contra o parceiro, a fim de averiguar os motivos que a levaram a requerer a extinção do processo, bem como o sentimento vivido por estas ante a negativa judicial, avaliando-se de forma exemplificativa alguns aspectos discutidos teoricamente.
Scope of this research is central to study the changes arising from the ADI 4424 and its implications for Maria da Penha Law. Thus, this study intends to verify that the new positioning of the STF is necessary for the realization of the fundamental right to gender equality, against sexism ingrained in Brazilian society, or whether it is a usurpation of women's autonomy and their right to choose? As a final goal, we intend to demonstrate that the complaint is a strong symbolic capital in the hands of women and the inability to retract the representation made against fellow, perhaps, from the perspective of the victim, is not beneficial for the suppression of domestic violence, because it is through it that the woman has tried to succumb to his inferiority before man or placed on a level equal to his. The method used is phenomenological. For this, we use the literature, documentary and field, collecting data through interviews with semi-structured, and through observational fieldwork in stick Specializing in Family and Domestic Violence against Women Vila Velha/ES. The research is divided into four chapters. The first one deals about the procedure, origin, purpose and arguments used by the bidder in ADI 4424 and the reasons for the vote of each Minister in his trial. In the second, we analyze, from the theory of Pierre Bourdieu, the gender issue as the relationship between rulers and ruled and the effects of these constructions. The third chapter will examine male dominance in Brazilian society, giving a brief history of women in law, as well as exposing statistical date, analyzing causes some influencers that lead men to attack and weighing about the struggle between women and abuse. The last chapter features interviews with some women who were prevented from portraying the representation made against the partner in order to ascertain the reasons which led it to request the dismissal of the case as well as the feeling experienced by these negative before the court, evaluating to form some exemplary aspects discussed theoretically.
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Ganoza, Luna Roberto Antonio. "Informe para la sustentación de expedientes: N° 258-2014/PS1 ARBITRAJE AD HOC S/N." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2021. http://hdl.handle.net/10757/656651.
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Este trabajo de suficiencia profesional, busca sustentar dos expedientes pertenecientes a las dos principales ramas del derecho. Por un lado, un expediente de derecho público, correspondiente a una controversia de protección al consumidor y, por otro lado, un expediente derecho privado, que busca determinar la naturaleza de un acto jurídico celebrado en el marco del derecho civil.
El primero de los expedientes, se trata de la controversia iniciada por la señora Denise Marissa Buckley Soto contra Lan Perú S.A. por la presunta infracción al deber de idoneidad del servicio, el cual habría sido afectado debido al retraso en el vuelo LA 2706 en la ruta Lima-Madrid.
El segundo caso bajo análisis, es la controversia entre José Luna García y su cónyuge, y la empresa Organización Peruana de Exportaciones Industriales S.A. – OPIESA, sobre de la naturaleza del acto jurídico que celebraron de forma verbal durante el primer trimestre el año 1997.
La posición de los señores Luna es que el acto jurídico celebrado fue un contrato de compraventa del Inmueble, mientras que la empresa Organización Peruana de Exportaciones Industriales S.A. – OPIESA, considera que se celebró un contrato de naturaleza asociativa, en el que los señores José Luna y su cónyuge, participaron en una asociación para el desarrollo de un proyecto inmobiliario.This work of professional sufficiency seeks to support two files belonging to the two main branches of law. On one hand, a public law file, that corresponds to a consumer protection dispute and, on the other hand, a private law file, which seeks to determine the nature of a legal act executed within the framework of civil law. The first of the files is the controversy initiated by Mrs. Denise Marissa Buckley Soto against Lan Perú S.A. for the alleged violation of the duty of suitability of the service, which would have been affected due to the delay in flight LA 2706 on the Lima-Madrid route. The second case under analysis is the controversy between José Luna García and his spouse, and the company Organización Peruana de Exportaciones Industriales S.A. – OPIESA, about the nature of the legal act that they celebrated verbally during the first quarter of 1997. The position of Mr. Luna is that the legal act was a contract for the sale of the property, while the company Organización Peruana de Exportaciones Industriales S.A. – OPIESA, considers that an agreement of an associative nature was executed, in which Mr. José Luna and his spouse participated in an association for the development of a real estate project.
Trabajo de suficiencia profesional
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Alves, Nathalia Novaes. "Elixir dos Gnósticos: a existência da alma humana em Mullā Ṣadrā." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/8/8159/tde-12052015-101441/.
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Figura-chave da chamada \"Escola de Isfahān\", Mullā Ṣadrā (979 H. / 1571-2 d.C ) ocupou papel de destaque durante a renascença safávida do reinado de Abbās I (d. 1039/1629). Acredita-se ter sido ele o principal responsável por revitalizar a filosofia da iluminação de Sūhrawardi naquele contexto, além de consolidar a junção entre sufismo e neoplatonismo. Foi responsável, ainda, pela elaboração de metodologia própria para a compreensão da realidade, tendo por base fontes filosóficas, teológicas e místicas, além de mesclar raciocínio lógico, inspiração espiritual e meditação profunda. Ṣadrā aplicou tal metodologia às principais obras da tradição xiita duodécima. Do ponto de vista filosófico, Ṣadrā percebe o conceito aristotélico de \"substância\" como processo, em constante mudança; nesse aspecto, o filósofo aproxima-se da leitura de traço neoplatônico, já presente em al-Fārābī e Ibn Sīnā. O modo como Ṣadrā relaciona as noções de \"essência\" e \"existência\" deu novas feições à discussão metafísica de tradição árabe-islâmica. Em sua doutrina, Ṣadrā acaba por transformar a metafísica construída a partir da primazia das substâncias, como elemento primordial da existência, em outra, fundada e movida por atos de existência. Apesar de perpassar esses e outros temas, a principal contribuição d\'O Elixir dos Gnósticos diz respeito à ênfase do autor no autoconhecimento. Como Ibn Ἁrabī, Ṣadrā acredita que o conhecimento da alma / nafs - ou seja, o conhecimento de si mesmo - e o conhecimento de Deus estão interligados. Por esse motivo, o presente trabalho se preocupou principalmente em analisar a relação entre os existentes, a alma e a inteligência primeira, pois é a partir dessa relação que se tornar possível vislumbrar e compreender as questões fundamentais da origem e do retorno à fonte doadora de existência. Do ponto de vista histórico, vale destacar que à fundação do império safávida acompanhou-se a conversão em massa da população ao xiismo. Para responder à demanda por instrução da multidão de novos convertidos - e igualmente firmar as bases da nova religião oficial -, grande número de religiosos foi trazido de áreas xiitas respeitadas pela doutrina e pela ortodoxia, tais como Líbano e Iraque. Esse clero árabe recém chegado, que teve Ṣadrā como herdeiro, foi responsável por incorporar novos elementos ao pensamento religioso vigente em terras persas e, assim, conformar ambiente propício para o desenvolvimento do pensamento filosófico de Ṣadrā.Prominent figure of the \"Isfahān School\", Mullā Ṣadrā (979 H. / 1571-2 AD) had an important role during the Safavid renaissance in the reign of Abbās I (d. 1039/1629). He is believed to be the main responsible for the revitalization of the philosophy of illumination of Sūhrawardi in that context, as well as for the consolidation of the junction between Sufism and Neoplatonism. He also developed his own methodology for the comprehension of the reality, based on philosophical, theological and mystics\' sources, and which puts together logical reasoning, spiritual inspiration and deep meditation. Ṣadrā applied his methodology to the then major works of the Twelver Shi\'ism tradition. From the philosophical point of view Ṣadrā perceives the Aristotelian concept of \"substance\" as a process in constant change; in this regard the philosopher comes nearer to the Neoplatonic ideas instead, as did al-Fārābī and Ibn Sīnā. The way Ṣadrā relates the notion of \"essence\" and \"existence\" added new features to the metaphysical discussions in Arabic and Islamic philosophical tradition. In his doctrine, Ṣadrā ends up transforming the metaphysics built upon the primacy of substances as the primordial element of existence, in another one based on and moved by acts of existence. The most important contribution of The Elixir of the Gnostics however is the emphasis of the author on self-knowledge. As Ibn Ἁrabī, Ṣadrā believes that the knowledge of the soul / nafs - in other words, the knowledge of the self - and the knowledge of God are interconnected. For this reason the present work is more concerned in analyzing the relation between existents, soul, and the first intelligence, from which it is possible to comprehend the fundamental issues of the origin and the return to the donor source of existence. From the historical point of view, it is worthy to highlight that the establishment of the Safavid Empire resulted in the mass conversion of the Persians into Shi\'ism. In order to respond to the increasing demand for religious instruction - and also to stabilize the basis for the new official religion - a great number of clerics was brought from Shiite areas recognized for their doctrine and orthodoxy, such as Lebanon and Iraq. This newcomer Arab clergy was responsible for incorporating new elements to the existing religious thought in Persian lands, and for creating a propitious context for the development of Ṣadrā\'s philosophical thought.
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ALTAMIRA, Asociación Peruana de Bibliotecas Académicas. "Boletín diario de información científica N° 25." Asociación Peruana de Bibliotecas Académicas ALTAMIRA, 2020. http://hdl.handle.net/10757/651908.
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Goldstein, Elon. "Ethics and Religion in a Classic of Sanskrit Drama: Harṣa's Nāgānanda." Thesis, Harvard University, 2013. http://dissertations.umi.com/gsas.harvard:11099.
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Secco, Pedro Ivo Dias. "Rumo ao pavilhão da eternidade: Nūruddīn e Šamsunnahār na literatura amorosa abássida." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/8/8159/tde-31072017-171238/.
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O Livro das Mil e Uma Noites, na forma como se encontra em seu grupo de manuscritos mais antigo, o chamado ramo sírio, configura-se como um grande compêndio de narrativas árabes de cunho erótico, em sua maioria. As cenas encontradas nessas narrativas, quase sempre explícitas, revelam mulheres sensualíssimas, donas de corpos desejados, e homens desejosos desses corpos e, na maioria das vezes, traídos por suas mulheres. Porém, uma narrativa em especial se destaca fortemente nesse universo carnal das Noites: a história de \"Nūruddīn ͨ Alī Bin Bakkār e Šamsunnahār\". O amor que tem lugar nessa narrativa beira o divino e inefável, e suas descrições, sempre imprecisas, revelam a dificuldade em se descrever um amor tão distante da carne e de seus desejos. Mas não é só no livro em questão que tal narrativa se destaca: dentro de toda a tradição amorosa da época a que pertence (entre os séculos IX e XI, no apogeu do Califado Abássida), tal como a conhecemos hoje, essa história de amor se mostra como única. O presente trabalho tem como objetivo analisar justamente esse destaque da narrativa de \"Nūruddīn ͨ Alī Bin Bakkār e Šamsunnahār\" dentro de seus contextos: primeiramente dentro do Livro das Mil e Uma Noites e, posteriormente, dentro da literatura amorosa abássida. Busca-se comparar a narrativa dos dois amantes com todas as outras narrativas erótico-amorosas das Mil e Uma Noites, demonstrando suas diferenças substanciais. Além disso, busca-se mapear a tradição literária amorosa abássida, demonstrando como Nūruddīn e Šamsunnahār nada têm que ver com os amantes das narrativas de amor da época. Ao final do trabalho, enumerando-se e analisando-se pormenorizadamente essas características de destaque, aproximamos a narrativa dos dois amantes a outras obras, contemporâneas a ela, que se declaram platonizantes. Assim, situamos a história de Nūruddīn e Šamsunnahār num pequeno e pouco estudado grupo de obras árabes medievais: o grupo que compartilha características que se assemelham às das obras platônicas e neoplatônicas.The Book of the Thousand and One Nights, in the way it is written in its oldest group of manuscripts, the Syrian branch, is composed as a big compendium of erotic Arabic stories, in its majority. The scenes found in those stories, which are almost always explicit, reveal very sensual women, owners of desired bodies, and men who desire those bodies, and who are, almost always, betrayed by those women. However, one story in special contrasts from the others in this carnal universe of the Nights: the story of \"Nūruddīn ͨ Alī Bin Bakkār and Šamsunnahār\". The love described in this narrative approaches the divine and ineffable love, and its descriptions, always imprecise, reveal the difficulty of describing a love, which is so distant from the body and its desires. But, the narrative of the two lovers is not a highlight only in this book: in the whole erotic tradition to which it belongs (the Abbasid love, between the IX and X centuries), this story shows itself as a unique one. The present dissertation aims to analyse these highlights of the narrative of \"Nūruddīn ͨ Alī Bin Bakkār and Šamsunnahār\" in its contexts: first, inside the Book of the Thousand and One Nights and, after that, inside the erotic Abbasid literature. We do it by comparing the story of the two lovers to all the other erotic narratives of the Nights, demonstrating all the substantial differences among them. Besides that, we draw a map of the whole erotic Abbasid literary tradition, demonstrating how Nūruddīn and Šamsunnahār have nothing in common with the other Abbasid lovers, described in the erotic stories of that time. At the end of the dissertation, by enumerating and analysing carefully those characteristics of highlight, we approach the narrative of the two lovers to other works, contemporary to it, which declare themselves to be platonic. By doing that, we situate the story of Nūruddīn and Šamsunnahār in a very small and not studied group of Arabic medieval works: the group, which shares similar characteristics with the platonic and neoplatonic works.
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Ribeiro, André Oswaldo Valença. "A relação entre nāḇî\' e miṯnabbê na Bíblia Hebraica." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/8/8158/tde-22012015-164817/.
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A heterogeneidade do profetismo israelita pode ser abordada de diversas maneiras. Na presente pesquisa, elegemos o binômio nāḇî\' e miṯnabbê como janela de observação para um estudo interdisciplinar dos fenômenos proféticos na Bíblia Hebraica, utilizando contribuições de diversas disciplinas. Nosso objetivo foi o de discutir uma questão que está sobre a mesa de debates dos pesquisadores, possuindo uma bibliografia que é vasta, porém inconclusiva A dificuldade dos scholars em afirmar em que medida o binômio nāḇî\'/miṯnabbê descreve ou não fenômenos distintos torna a questão complexa e instigante. Os capítulos do trabalho acompanham o recorte do estudo, que é composto por quatro narrativas: Nm 11, 1 Sm 10, Ez 13 e Mq 3. A forma participial miṯnabbê descreve o comportamento dos anciãos em face do nāḇî\' Moisés (Nm 11), a performance de Saul diante de um ḥeḇel neḇiʼim (grupo de profetas) em êxtase e ao som de música (1 Sm 10), bem como a atividade das profetisas-miṯnabb ͤ ʼōṯ, cuja racionalidade (designada pelo termo lêḇ, \"coração\") obstinada (šrr) é criticada pelo nāḇî\' Ezequiel (Ez 13). A condição profética dos anciãos e de Saul se relaciona com a vinda do ruaḥ (sopro, espírito) divino. O substantivo nāḇî\' está em questão também na crítica ao pagamento do profeta ávido por enganar (šeqer) e \"morder\" (nōšek) lucros e benefícios(Mq 3). Por meio do exame dessas passagens, levantamos discussões que resultaram em um comentário crítico sobre o profetismo israelita, que destaca a abertura de possibilidades de pesquisa suscitada pelo binômio nāḇî\'/miṯnabbêThe heterogeneity of the Israelite prophecy can be approached from several ways. In this study, we chose the binomial nāḇî\' and miṯnabbê as an observation window to an interdisciplinary study of the prophetic phenomena in the Hebrew Bible, using input from several disciplines. Our goal was to discuss an issue that is present in the current discussions of researchers, having a bibliography that is extensive but inconclusive. The difficulty researchers have to state to which extent the binomial nāḇî\'/miṯnabbê describes or not distinct phenomena makes the issue complex and instigating. The chapters of this work follow the scope of the study, which consists of four narratives: Nu 11, 1 Sa 10, Eze 13 and Mic 3. The participial form miṯnabbê describes the behavior of elders in the face of nāḇî\' Moses (Nu 11), the performance of Saul before a ḥeḇel neḇiʼim (group of prophets) in ecstasy and at the sound of music (1 Sa 10), as well as the activity of the prophetesses - miṯnabb ͤ ʼōṯ, whose obstinate (šrr) rationality (designated by the term lêḇ,\"heart\") is criticized by the nāḇî\' Ezekiel (Eze 13). The prophetic condition of the elders and Saul relates to the coming of the divine ruaḥ (blow, spirit). The noun nāḇî\' is emphasized also in the criticism about the payment of the prophet eager to cheat (šeqer) and to \"bite\" (nōšek) profitsand benefits(Mic 3). Through the examination of these passages, we raised discussions that resulted in a critical commentary on the Israelite prophecy, which highlights the opening of research possibilities raised by the binomial nāḇî\'/miṯnabbê
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Souza, Emily Fonseca de. "A unificação da Síria e o jihād de Nūr ad-Dīn na crônica Kitāb al-Kāmil fi l-ta\'rīkh, de Ibn al-Athīr." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/8/8138/tde-25102016-115357/.
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Em nossa dissertação, estudamos o excerto da crônica Kitāb al-Kāmil fi l-ta\'rīkh, de Ibn al-Athīr, que relata os anos de governo de Nūr ad-Dīn. Nossa pesquisa é dividida em três partes. Na primeira, apresentamos o autor e sua obra, a origem e a composição da crônica, além do debate historiográfico sobre a obra. Na segunda, abordamos os gêneros retóricos da Retórica de Aristóteles e a aplicação de dois destes gêneros, epidítico e deliberativo, na composição do discurso de Ibn al-Athīr. Na terceira, realizamos uma síntese das definições de jihād tanto no Alcorão quanto nos tratados jurídicos muçulmanos e mostramos como o nosso autor se apropria deles para legitimar as ações de Nūr ad-Dīn e construir, por meio de seu discurso, a figura do biografado como um exemplo de governante.In our dissertation, we study the extract of Ibn al-Athīr\'s chronicle, Kitāb al-Kāmil fi l-ta\'rīkh, reporting the years of Nūr ad-Dīn\'s governmet. Our research is divided into three parts. The first presents the author and his work, the chronicles origin and the composition, besides presenting the historiographical debate on the work. The second approachs the rhetoric genres of Aristotles Rhetoric and the use of two of these genres, epideictic and deliberative, at the construction of Ibn al-Athīr\'s discourse. The third discusses the definitions of jihād both at Coran and at muslims juridical treatises, indicating how our author uses them to legitimate Nūr ad-Dīn\'s action in order to elaborate him, through his discourse, as an example of ruler.
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Tuazon, Allen L. "“Understanding” in Revelation: the root ‘-Q-L in the Qur’ān." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1306868259.
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Müller, Stefan. "Überkompensatorische Schmerzensgeldbemessung? : ein Beitrag zu den Grundlagen des Paragraph 253 Abs. 2 BGB n. F. /." Karlsruhe : VVW, 2007. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=015725938&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
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Girolametto, Agnese <1995>. "Le Informazioni non finanziarie e il Decreto Legislativo n. 254/2016 nel sistema di bilancio." Master's Degree Thesis, Università Ca' Foscari Venezia, 2019. http://hdl.handle.net/10579/15334.
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In questa tesi vengono approfonditi i contenuti della relazione sulla gestione e della dichiarazione non finanziaria, con particolare attenzione alle informazioni sul personale e sull'ambiente. Dopo qualche nozione generale sulla relazione sulla gestione, ho approfondito i contenuti previsti dall'articolo 2428 del Codice Civile. In seguito all'emanazione del Decreto Legislativo numero 254 del 30/12/2016 (che recepisce la direttiva europea 2014/95/UE), gli enti di interesse pubblico rilevanti sono tenuti a presentare una dichiarazione non finanziaria. Ho analizzato tutti i dodici articoli di tale decreto e le disposizioni del regolamento attuativo emanato il 18/01/2018 dalla commissione nazionale per le società e la borsa. Le società sono libere di presentare la dichiarazione non finanziaria seguendo lo standard di rendicontazione che preferiscono o adottando una metodologia autonoma di rendicontazione. In questo elaborato vengono approfonditi solo gli standard emanati dal Global Reporting Initiative e dall’International Integrated Reporting Council. In seguito all'integrazione delle informazioni non finanziarie con le informazioni finanziarie contenute nel bilancio d'esercizio, ci si sta orientando sempre più verso il bilancio integrato. Nell’ultimo capitolo vengono analizzate le implicazioni dell’integrated thinking ed i vantaggi che scaturiscono dall’uso della reportistica integrata.
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Milani, Nicolo' <1994>. "Le "operazioni baciate" nel contesto del d.l. 25 giugno 2017, n. 99." Master's Degree Thesis, Università Ca' Foscari Venezia, 2019. http://hdl.handle.net/10579/15525.
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Il presente lavoro mira nella prima parte ad esaminare le c.d. "operazioni baciate" poste in essere dalla Banca Popolare di Vicenza e da Veneto Banca in relazione a due recenti ordinanze del Tribunale di Venezia. Nella seconda parte invece, si cercheranno di capire le possibili conseguenze di tali operazioni alla luce della messa in liquidazione delle due banche venete e del loro acquisto da parte di Banca Intesa, in attuazione di quanto previsto dal d.l. 25 giugno 2017, n. 99 e del relativo contratto di cessione da esso richiamato.
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GUYOT, PASCALE. "Interet de l'echographie cardiaque dans un service d'urgence : a propos des 258 dossiers du pavillon n 1." Lyon 1, 1993. http://www.theses.fr/1993LYO1M264.
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Jaeger, Michael. "Die Einfangreaktion 22 Ne(Alpha,n) 25 Mg - die Hauptneutronenquelle in massiven Sternen /." [S.l. : s.n.], 2001. http://www.bsz-bw.de/cgi-bin/xvms.cgi?SWB9918596.
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Kubala, Ricardo Lobo. "A escrita para viola nas sonatas com piano Op.11 N.4 e Op.25 N.4 de Paul Hindemith : aspectos idiomaticos, estilisticos e interpretativos." [s.n.], 2004. http://repositorio.unicamp.br/jspui/handle/REPOSIP/284851.
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Orientador: Emerson Luiz de BiaggiDissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Artes
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Resumo: O surgimento de repertório de maior relevância para viola foi resultado de procura por identidade do instrumento, da qual participaram compositores e intérpretes. Paul Hindemith foi figura marcante nessa busca. Compôs várias obras de importância para viola, como as sonatas Op.11 NQ 4 (1919) e Op.25 NQ 4 (1922), as quais, apesar de cronologicamente próximas, apresentam acentuada diferenciação estilística. São examinadas as causas desse contraste e suas conseqüências no âmbito da prática interpretativa. Buscando subsídios para o estudo das sonatas, inicialmente é traçado um relato sobre vida, obra e idéias de Hindemith, com enfoque em sua faceta multi-instrumentista e a variedade estilística de sua produção. Segue-se uma reflexão sobre a evolução de uma escrita para viola com maior preponderância de aspectos idiomáticos, que fornece dados relativos a aspectos específicos da prática instrumental da viola. A investigação de ambas as sonatas é realizada, então, por meio da observação de características estilísticas, associadas, por sua vez, a aspectos concernentes à prática interpretativa. A pesquisa visa fornecer conhecimento que contribua para uma execução eficiente em sua comunicação com o público
Abstract: A more relevant repertoire for the viola emerged as a result of the search by composers and interpreters for the instrument's identity. Along with other composers and performers such movement showed Paul Hindemith as an important figure. He wrote several major works for viola including the sonatas Op.11 NA (1919) and Op.25 NA (1922). In spite of their chronological proximity these sonatas show clearly distinct styles. The present study examines the causes of that contrast and its consequences to practical interpretation. In order to investigate thoroughly the sonatas, Hindemith's life, work and ideas are also described. The composer's ability and interest in playing several instruments as well as a variety of styles within his work are also highlighted. In addition, the present work discusses the evolution of the writing for the viola that is rich in idiomatic elements demonstrating very specific aspects of the viola playing. The study of the sonatas is based on the analysis of their stylistic features associated with aspects of performance practice. The purpose of the present research is to offer musicians data that may contribute to an efficient performance in the communication with the audience
Mestrado
Musica
Mestre em Música
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Pasini, Andrea <1994>. "Il decreto legge n.91 del 25 luglio 2018: una correzione alla riforma delle BCC." Master's Degree Thesis, Università Ca' Foscari Venezia, 2020. http://hdl.handle.net/10579/16336.
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Il 25 luglio 2018 è stato emanato il decreto legge n.91 (entrato poi in vigore il 26 luglio con la pubblicazione sulla Gazzetta Ufficiale), definito in gergo politico-giornalistico “decreto Milleproroghe”. Questo decreto legge è stato poi convertito dal Parlamento con legge di conversione il 21 settembre 2018 (n.108). Il provvedimento del 25 luglio 2018 è composto da 14 articoli, i quali vanno a toccare diverse materie dall’istruzione al finanziamento degli investimenti, dalla cultura allo sport, dalla salute ai gruppi bancari assicurativi. In tutti questi argomenti compaiono modifiche, integrazioni e sostituzioni, sia di contenuto temporale che di contenuto concettuale. Attraverso l’elaborazione di questa tesi il mio intento non sarà quello di affrontare tutti i punti del provvedimento, ma sarà quello di analizzare l’articolo 11 del provvedimento, ovvero “Proroga di termini in materia di banche popolari e gruppi bancari cooperativi”.
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Canet, Patrick. "La vérification et l'admission des créances dans la loi n° 85-98 du 25 janvier 1985." Paris 1, 1989. http://www.theses.fr/1989PA010258.
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La loi no 85-98 du 25 janvier 1985 relative au redressement et a la liquidation judiciaires des entreprises a modifie le s regles de verification et d'admission des creances. La these examine le role des organes de la procedure (le representant des creanciers, l'administrateur judiciaire, le ju ge commissaire, etc. . . ); elle decrit les operations de verification tant en redressement judiciaire qu'en liquidation ju diciaire; dans un deuxieme temps est etudie le contentieux ne de la verification ou de l'admission : - contestation des creances par le representant des creanciers, - creances declarees hors delais, - recours contre les decisions du juge commissaire. La these aboutit a des propositions de modifications legislativesThe law no 85-98 of january 25th, 1985 relating to the redressing and winding up businesses has modified the rules of au diting and acceptance of claims. The thesis examines the role of the organs of the procedure (the representative of the creditors, the official receiver, the judge setting in bankruptcy cases, etc. . . ); it describes the operations of auditing in judicial redressing as well as in winding up; it then goes on to study the litigation that has come out the auditing or acceptance of claims : - contesting of claims by the creditors' representative - claims declared beyond deadline - recourse against the decisions of the judge setting in bankryptcy cases the thesis concludes with some legislative modification proposals
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Midy, Carole. "Pour une réhabilitation de l'article L. 182 de la loi n°85-98 du 25 janvier 1985." Paris 5, 2001. http://www.theses.fr/2001PA05D016.
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L'article L. 182 de la loi sur les procédures collectives du 25 janvier 1985 est une disposition souvent méconnue et diversement appréciée. Ce texte organise un mécanisme de répression d'actes considérés comme illicites, commis par les dirigeants sociaux dans l'exercice de leurs fonctions, au sein d'une ou plusieurs entreprises. L'article L. 182 trouve sa richesse en ce qu'il regroupe les notions essentielles du droit des procédures collectives, puisqu'il a pour vocation première d'étendre au dirigeant fautif la procédure de redressement (ou de liquidation) judiciaire prononcée à l'encontre de la société qu'il dirigeait. Il envisage donc de sanctionner patrimonialement le dirigeant fautif, avec une mesure d'une particulière gravité puisque celui-ci subit directement et personnellement l'ensemble des conséquences inhérentes au prononcé d'une telle procédure collective. Mais l'article L. 182 appréhende aussi tant certains éléments substantiels du droit des sociétés en général, que certaines infractions majeures relevant du droit pénal des affaires. Abus de biens sociaux et délit de banqueroute pourront donc se superposer au prononcé d'une procédure collective pour le diregeant social, dont les agissements étaient susceptibles d'un concours de qualifications et donc d'un cumul de sanctions. Ce texte organise ainsi un système de responsabilité unique en son genre puisqu'un dirigeant social peut, sur ce même fondement, encourir des sanctions tant civiles, personnelles que pénales. Pèse donc sur le dirigeant social la menace des représailles prévues par l'article L. 182, dont le champ d'application est ellement vaste qu'il met en exergue la gravit des responsabilités ainsi encourues, et dont il faudra apprécier la légitimité et lopportunité des critères d'application. Disposition originale et d'une effficacité redoutable, l'article L. 182 cristallise nombres d'interrogations contemporaines posées par le droit des sociétés en général et appréhende les difficultés à venir dans l'optique d'une réforme de toutes les branches du droit relatives aux entreprises et aux commerçantsThe content L. 182 enclosed with the law which organize the insolvency hereby a proceeding for judicial reorganization designed to assure the preservation of the enterprise, the continuation of its activity and the use and discharge of its liabilities. The judicial reorganization is effected according to a plan ordered by a judicial decision following a period of observation. This plan provides either for the continuation of the enterprise or for its sale. If weither of these solutions appears feasible, judicial liquidation is commenced. (Law. No. 85-98 of January. 25, 1985. Art. 1). Judicial reorganization is applicable to every merchant, every artisan and every legal person of private law ( Law. No. 85-98 of January. 25, 1985. Art. 2). But the insolvency is also applicable to every person considered as the eader, managing the company in law and in fact. The insolvency’s “extension “ is applicable to the leader of the company, if he has committed one or several acts aimed at the article L. 182. This extension is possible to the leader who exercises the powers conferred upon the shareholder’s meeting. He assumes and takes responsibility for the general management of the corporation. He represents the company in its relations with third parties. In fact, during the judicial reorganization, the leader of the company can be liable for the faults he used to do in past, if he has contributed to deteriorate the company’s situation. The leader is responsible for the pecuniary and non-pecuniary less he has caused, not only by his acts, but also by his neglect or impudence. The content of the “article L. 182 “organizes the mechanics of his liability and the leader may incur in criminal and civil liabilities. If the leader has done one more unlawful acts when he was in office, the article L. 182 makes him be condamned to bear a personnal judicial reorganization, as if he was a legal person of private law. More than that, the other punishments in question can be criminal, by imprisonment and by a fine. The article L. 182 is a wealth concept, between commercial law and criminal law. It is one of a kind very attractive, which is unfairly appreciated. This is why its needs our “rehabilitation”
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Han, Liang. "Exploring two-phase hydrothermal circulation at a seafloor pressure of 25 MPa: Application for EPR 9°50′N." Thesis, Virginia Tech, 2011. http://hdl.handle.net/10919/45440.
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We present 2-D numerical simulations of two phase flow in seafloor hydrothermal systems using the finite control volume numerical scheme FISHES. The FISHES code solves the coupled non-linear equations for mass, momentum, energy, and salt conservation in a NaCl-H2O fluid to model the seafloor hydrothermal processes. These simulations use homogeneous box geometries at a fixed seafloor pressure of 25 MPa with constant bottom temperature boundary conditions that represent a sub-axial magma chamber to explore the effects of permeability, maximum bottom temperature and system depth on the evolution of vent fluid temperature and salinity, and heat output. We also study the temporal and spatial variability in hydrothermal circulation. The two-phase simulation results show that permeability plays an important role in plume structure and heat output of hydrothermal systems, but it has little effect on vent fluid temperature and salinity, given the same bottom temperature. For some permeability values, multiple plumes can vent at the seafloor above the simulated magma chamber. Temporal variability of vent fluid temperature and salinity and the complexity of phase separation suggest that pressure and temperature conditions at the top of the axial magma chamber cannot be easily inferred from vent fluid temperature and salinity alone. Vapor and brine derived fluids can vent at the seafloor simultaneously, even from neighboring locations that are fed by the same plume.Master of Science
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Kernan, Thomas J. "The Percussion Group Cincinnati: A History of Collaboration between Ensemble and Composer." University of Cincinnati / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1275918212.
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Acioli, José Adelmy da Silva. "A possibilidade da prisão civil do depositário judicial infiel : revisitando a súmula vincunlante n. 25 do Supremo Tribunal Federal." Universidade Católica de Pernambuco, 2011. http://www.unicap.br/tede//tde_busca/arquivo.php?codArquivo=593.
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Objetiva-se demonstrar que a prisão civil do depositário judicial infiel continua sendo possível no Brasil, mesmo em face da ratificação da Convenção Americana de Direitos
Humanos de 1969. Busca-se estudar a natureza jurídica de cada espécie de depósito e, a partir desse referencial teórico, aferir-se que a hipótese do depositário judicial não possui índole contratual, mas de direito público, não se envolvendo com a dívida em execução, nem com nenhum outro elemento de direito privado, podendo o encargo recair sobre o próprio credor ou sobre terceiro. Nesse sentido, a prisão do depositário judicial infiel não seria por dívida, mas como decorrência do desacato (contempt) revelado pelo descumprimento dos encargos processuais de direito público por si assumidos perante o juiz da execução, não estando
abrangida pela proscrição estabelecida por aquela norma internacional. Por outro lado, analisa-se o conflito de direitos fundamentais envolvendo a liberdade individual e as garantias
de acesso à justiça e da efetividade da tutela jurisdicional, concluindo-se que os velhos critérios hermenêuticos de solução de antinomias são insuficientes ao exame da questão,
devendo ser dada uma interpretação constitucional adequada em cada caso concreto com supedâneo no princípio da proporcionalidade. Analisa-se, também, hermenêutica e
linguisticamente, a referência legislativa e cada um dos precedentes judiciais da súmula vinculante n. 25 do Supremo Tribunal Federal, verificando-se que o conflito foi apreciado
jurisprudencialmente apenas sob o âmago do confronto entre os direitos de liberdade e de propriedade, turvando-se o olhar investigativo sobre a tensão que aquela decisão sumular, tal
como redigida, enseja em relação às garantias de acesso à justiça e de efetividade da tutela jurisdicional. Desse modo, conclui-se que a súmula vinculante n. 25 precisa ser revisada pelo STF, e, até que isso aconteça, impõe-se que seja dada uma interpretação constitucional adequada à sua redação, a fim de se restringir sua destinação apenas aos depositários
contratuais, não alcançando os depositários judiciais
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Wehbe, Nimer. "Émission ionique des solides à l'impact d'agrégats Aun+ (n=1-9) accélérés entre 0. 15 et 1. 25 MeV." Lyon 1, 2006. http://tel.archives-ouvertes.fr/docs/00/09/76/71/PDF/Thesewehbe.pdf.
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Ce travail expérimental est consacré à l'étude de l'émission ionique des solides à l'impact d'agrégats d'or d'énergie variant entre 0,15 et 1,25 MeV. La physique des collisions ion-solide et les modèles théoriques de la pulvérisation des solides par bombardement ionique sont présentés dans le chapitre 1. Le chapitre 2 est consacré à la description du dispositif expérimental. L'étude d'une cible d'or, présentée dans le chapitre 3, a permis de montrer le rôle de la taille et de l'énergie des agrégats sur l'intensité de l'émission et la distribution de masse des ions. Le chapitre 4 présente l'étude de l'iodure de césium dans laquelle l'intense émission des agrégats de CsI a pu être quantifiée grâce à des mesures de la multiplicité de l'émission. Le chapitre 5 est consacré à l'étude d'une molécule biologique, la phénylalanine, et d'une molécule de pesticide, le chlorsulfuron. Ce travail met en évidence l'intérêt des agrégats en analyse de surface par spectrométrie de masseThis experimental work is devoted to the study of the ion emission of solids under the impact of gold clusters of energy ranging between 0. 15 and 1. 25 MeV. The physics of ion-solid collisions and the theoretical models of solid sputtering by ion bombardment are presented in chapter 1. Chapter 2 is devoted to the description of the experimental setup. The study of a gold target, presented in chapter 3, allows us to show the role of the size and the energy of the clusters on the intensity of the emission and on the mass distribution of the ions. Chapter 4 presents the study of cesium iodide in which the intense emission of CsI clusters has been quantified from measurements of the emission multiplicity. Chapter 5 is devoted to a study of a biological molecule, phenylalanine, and a molecule of pesticide, the chlorsulfuron. This work points out the interest of clusters for surface analysis by mass spectrometry
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Michua, Corona María Guadalupe, and Figueroa Jonathan Ramirez. "Manejo de heridas crónicas con terapia de presión negativa ambulatoria por profesionales de enfermería en el servicio de clínica de heridas del H.G.R N° 251." Tesis de Licenciatura, Universidad Autónoma del Estado de México, 2016. http://hdl.handle.net/20.500.11799/67972.
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El empleo de la terapia de presión negativa es una opción ampliamente extendida
para el manejo de heridas crónicas, promueve la curación mediante la aplicación
de presión negativa, de manera que el uso de niveles controlados de presión subatmosférica
y succión controlada, acelera la resolución de las mismas
favoreciendo la vascularización y el desbridamiento. Actualmente, este sistema se
considera una intervención fundamental en el tratamiento de las heridas
complejas, las cuales suponen un reto terapéutico importante y muchas veces
generan un largo y costoso egreso hospitalario. Gracias a la terapia de vacío se
puede disminuir el tamaño de dichas heridas a la par que se protegen de la
infección, haciendo innecesario el uso prioritario de colgajos libres y grandes
intervenciones. La terapia de presión negativa se remonta a miles de años atrás,
se utilizó por primera vez como tratamiento complementario; a nivel básico, la
presión negativa constituye un apósito sofisticado, estéril y cerrado con
propiedades que hacen que el entorno para la cicatrización de la herida sea
húmedo.
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Abdel-Khalek, F. [Verfasser]. "Untersuchung der Reaktion π⁻p-->π⁰eta⁰n bei Pionimpulsen von 25 und 40 GeV/c / F. Abdel-Khalek." Karlsruhe : KIT-Bibliothek, 2012. http://d-nb.info/1190100312/34.
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Lima, Rodrigo Ot?vio Souza. "Lei geral de concursos p?blicos: an?lise do Projeto de Lei n? 252/2003 e suas implica??es nos concursos p?blicos para o magist?rio federal da Universidade Federal do Rio Grande do Norte." PROGRAMA DE P?S-GRADUA??O EM GEST?O DE PROCESSOS INSTITUCIONAIS, 2016. https://repositorio.ufrn.br/jspui/handle/123456789/22311.
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O presente trabalho analisa o Projeto de Lei n? 252/2003, conforme texto substitutivo apresentado em 09/10/2013 pela Comiss?o de Constitui??o e Justi?a e de Cidadania da C?mara dos Deputados, o qual se prop?e a regulamentar as normas gerais relativas a concursos p?blicos de provas ou de provas e t?tulos no ?mbito da Administra??o Direta e Indireta da Uni?o, nos termos do art. 37, inciso II, da Constitui??o Federal de 1988, e as suas implica??es nos certames para o ingresso em cargo efetivo nas carreiras do Magist?rio Superior e do Magist?rio do Ensino B?sico, T?cnico e Tecnol?gico, realizados pela Universidade Federal do Rio Grande do Norte ? UFRN. A aus?ncia de regulamenta??o espec?fica e detalhada desse instituto gera inseguran?a jur?dica e delega ao Poder Judici?rio o papel normativo. Neste sentido, o Projeto de Lei n? 252/2003 visa tornar mais clara as rela??es jur?dicas e os procedimentos de investidura no servi?o p?blico por meio do concurso p?blico. Busca-se com este estudo a apresenta??o de uma proposta de interven??o, tendo como produto uma minuta de nova resolu??o, tendente a aprimorar e atualizar o normativo interno vigente sobre a mat?ria, a saber, Resolu??o n? 108/2013-CONSEPE, de 2 de julho de 2013, deixando-a mais transparente e coesa com os princ?pios constitucionais e a jurisprud?ncia dominante. Para tanto, a pesquisa vale-se do m?todo dedutivo-indutivo de abordagem, servindo-se dos procedimentos hist?rico e comparativo para uma an?lise sistem?tica e teleol?gica dos concursos p?blicos, especificamente ?queles voltados para o provimento em cargo efetivo do Magist?rio Federal, aplicando a jurimetria como crit?rio de avalia??o de adequa??o da proposta, ante a natureza do objeto em estudo.
The present study analyzes the Bill n?. 252/2003, according to the replacement text presented in 10/9/2013 by the Committee on Constitution and Justice and Citizenship of the Chamber of Deputies, which proposes to regulate the general rules of civil service examinations of tests, or tests and professional qualifications evaluation under the Direct and Indirect Administration of the Union, in accordance with article 37, II, of the 1988 Federal Constitution, and its implications in competitions for entry into effective position in the career of Federal Magisterium (Magisterium Higher and Basic Education, Technical and Technological) conducted by the Universidade Federal do Rio Grande do Norte - UFRN. The lack of specific and detailed regulations of this institute creates legal uncertainty and delegates to the Judiciary the normative role. In this sense, the Bill Project n?. 252/2003 aims to clarify the legal relations and investiture procedures in the public service through public examinations. We seek with this study to present an intervention proposal, having as a product a draft of a new normative, aimed at improving and updating the current internal regulations on the matter, namely, Normative Resolution n? 108/2013-CONSEPE, July 2, 2013, making them more transparent and cohesive with the constitutional principles and the prevailing jurisprudence. Therefore, the research uses the deductive - inductive approach, making use of historical and comparative procedures for systematic and teleological analysis of public examinations, specifically geared to the provision in the effective charge of the federal teaching, applying jurimetrics as criteria for evaluating the adequacy of the proposal, given the nature of the object under study.
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Guo, Zheng. "The effects of protective or risk factors on suboptimal health status evaluated by subjective or objective measures." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 2023. https://ro.ecu.edu.au/theses/2651.
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Background
Suboptimal health status (SHS) is an intermediate and reversible stage between health and disease and has become a major public health concern worldwide. SHS is characterised by chronic fatigue, perception of health complaints, general weakness, and a cluster of lasting physical symptoms. Therefore, it is warranted to comprehensively investigate the potential protective or risk factors for SHS and the possible measures to evaluate SHS to inform the prevention for SHS and subsequent diseases.
Objectives
Study I. To explore the effects of tourism-related characteristics on SHS in a cross-sectional study.
Study II. To determine whether 2-week severe physical activity restriction induces pro-inflammatory alterations in immunoglobulin G (IgG) N-glycosylation profiles.
Study III. To translate the Suboptimal Health Status Questionnaire-25 (SHSQ-25) from its English version into the Korean language and to evaluate the validity and reliability of the Korean version of SHSQ-25 (K-SHSQ-25) in a Korean population.
Methods
Study I. A cross-sectional study was conducted between October and December 2021 in Shandong Province, China. Individuals were recruited via convenience sampling; all potential respondents were approached at random. SHSQ-25 was used to identify the SHS of the participants. Modified Poisson regression was the primary method to evaluate associations between tourism-related characteristics on SHS.
Study II. A quasi-experimental study was conducted within the parental clinical trial, Nutrition and Exercise Training (NExT) Study, with a sample of 79 healthy female participants from 40 to 60 years old. The participants were directed to exert their maximum effort towards reducing their daily step count monitored and recorded by a pedometer. The IgG N-glycosylation profile, which is an objective marker for SHS, was compared before and after physical activity restriction.
Study III. This study was carried out to translate SHSQ-25 from English into Korean according to international guidelines set forth by the World Health Organization (WHO) for health instrument translation between different languages. A subsequent cross-sectional study was conducted to evaluate the validity and reliability of K-SHSQ-25 in a Korean sample.
Results
In Study I, 360 participants were included in the final analysis. The prevalence of SHS in the participants was 36.4% (131/310), with 67.2% for females and 32.8% for males. Poisson regression analysis with SHS as the dependent variable indicated that tourism expenditure during one’s prior trip (1,001-5,000 RMB; P = 0.006) was a risk factor significantly associated with SHS. Conversely, preference for domestic travel (Group tour, P = 0.006) was a significantly protective factor for SHS.
In Study II, during the 2-week activity restriction period, the daily step count was reduced by 76.8% to 1830 ± 680 steps per day. After physical activity restriction, the abundances of monogalactosylated and digalactosylated IgG N-glycans were reduced by 0.41 (95% CI -0.95 to -0.20; P = 0.045) and 0.53 (95% CI -0.88 to -0.18; P = 0.041), respectively.
In Study III, the K-SHSQ-25 achieved linguistic, cultural, and conceptual equivalence to the English version. The intraclass correlation coefficient of test-retest reliability for individual items ranged from 0.88 to 0.99. Reliability estimated based on internal consistency reached a Cronbach’s α of 0.953. The confirmatory factor analysis revealed that the root-mean-square error of approximation (RMSEA), goodness-of-fit index (GFI) and adjusted goodness of fit index (AGFI) were excellent (RMSEA = 0.069 < 0.08, GFI = 0.929 > 0.90, AGFI = 0.907 > 0.90). Regarding convergent validity, the five domains of the K-SHSQ-25 showed significant correlations with each other (r: 0.59-0.81, P < 0.001).
Conclusions
Study I. Findings suggested that tourism activities may serve as ideal interventions for leveraging SHS. In addition, tourism may present a new avenue for contributing to global health studies.
Study II. Short periods of enforced activity restriction, including those resulting from COVID lock-down or isolation, can trigger pro-inflammatory changes in IgG N-glycosylation profiles.
Study III. Results indicated that the Korean version of SHSQ-25, K-SHSQ-25 is a transcultural equivalent, robust, valid, and reliable assessment tool for evaluating SHS in the Korean-speaking population.
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Cutcher, Lauren M. "Human Rights Policy After the Dirty War: State and Civil Society in Argentina (1983-1989)." Ohio : Ohio University, 2009. http://www.ohiolink.edu/etd/view.cgi?ohiou1243883552.
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Ramos, Rafaela. "Associa????o entre os polimorfismos BsmI e FokI do gene VDR, n??veis s??ricos de 25(OH)D e susceptibilidade ?? osteoporose em idosas." Universidade Cat??lica de Bras??lia, 2016. https://bdtd.ucb.br:8443/jspui/handle/tede/2171.
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Osteoporosis (OP) is a common osteometabolic disease among the elderly and may be associated with genetic components that influence bone metabolism. Due to regulatory action of vitamin D in osteomineral physiology, the expression of the vitamin D receptor gene (VDR) in bone tissue, it is able to influence the genetic determinants of bone mineral density (BMD) and the OP. Studies report the existence of polymorphisms related to the pathogenesis of OP, which can lead to changes in the mechanisms of the action of vitamin D. The BsmI and FokI polymorphisms were associated with changes in BMD suggesting thus a higher incidence and prevalence of fractures due to bone fragility. The objective of this study was to associate the presence of BsmI and FokI polymorphisms located in VDR gene, serum levels of 25(OH)D and susceptibility to OP for elderly women. It was observed that 58% of the study sample had levels of 25(OH)D below the threshold considered sufficient and 62% showed changes in BMD values consistent with the diagnosis of osteopenia or osteoporosis. For elderly women, vitamin D levels are not related to the reduction of BMD and presence of polymorphisms. In the evaluation of polymorphic sites it was found that, in this sample, 28% were positive for FokI polymorphism and 10% were positive for BsmI. The described results show that in elderly women, the BsmI polymorphisms FokI and are not related to vitamin D and osteoporosis.
A osteoporose (OP) ?? uma afec????o osteometab??lica comum em idosos, associada ou n??o a componentes gen??ticos que influenciam no metabolismo ??sseo. Devido ?? a????o reguladora da vitamina D na fisiologia osteomineral, a express??o do gene receptor da vitamina D (VDR) no tecido ??sseo ?? capaz de exercer influ??ncia na determina????o gen??tica da densidade mineral ??ssea (DMO) e OP. Estudos reportam a exist??ncia de polimorfismos relacionados com a etiopatogenia da OP os quais podem determinar altera????es nos mecanismos de a????o da vitamina D. Os polimorfismos BsmI e FokI foram associados com varia????es na DMO sugerindo uma maior incid??ncia e preval??ncia de fraturas por fragilidade ??ssea. Desta forma, o objetivo deste estudo foi associar a presen??a dos polimorfismos BsmI e FokI localizados no gene VDR, as concentra????es s??ricas de 25-hidroxivitamina D (25(OH)D) e a susceptibilidade ?? osteoporose em idosas. Para tanto, foram inclu??das 50 idosas com m??dia de idade de 71,74 ?? 7,80 anos (60 ??? 94 anos). Os polimorfismos BsmI e FokI foram pesquisados e os dados sobre os n??veis de 25(OH)D e DMO foram coletados mediante acompanhamento ambulatorial. Observou-se que 58% da amostra estudada possui n??veis de 25(OH)D abaixo do limiar considerado suficiente e 62% apresentaram altera????es nos valores de DMO compat??veis com o diagn??stico de osteopenia ou osteoporose. Nas idosas avaliadas os n??veis de vitamina D n??o est??o relacionados com a redu????o da DMO e presen??a dos polimorfismos. Na avalia????o dos s??tios polim??rficos verificou-se que, nessa amostra, 28% apresentaram resultado positivo para o polimorfismo FokI e 10% apresentaram positividade para BsmI. Os resultados descritos evidenciam que, nas idosas avaliadas, os polimorfismos BsmI e FokI n??o se encontram relacionados com os n??veis de vitamina D e osteoporose.
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Rioseco, Marcelo A. "Elementos lúdicos en la poesía de Juan Luis Martínez, Diego Maquieira y Rodrigo Lira." University of Cincinnati / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1226449391.
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Gomez, Leonardo Ph D. Massachusetts Institute of Technology. "Electron transport in ultrathin-body fully depleted n-MOSFETS fabricated on strained silicon directly on insulator with body thickness ranging from 22nm to 25 nm." Thesis, Massachusetts Institute of Technology, 2006. http://hdl.handle.net/1721.1/38671.
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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, February 2007.Includes bibliographical references (leaves 49-53).
The electron effective mobility in ultrathin-body (UTB) n-MOSFETs fabricated on Ge-free 30% strained-Si directly on insulator (SSDOI) is mapped as the body thickness is scaled. Effective mobility and device body thickness were extracted using current-voltage and gate-to-channel capacitance-voltage measurements as well as cross section transmission electron microscopy. Devices with body thicknesses ranging from 2 nm to 25 nm are studied. Significant electron mobility enhancements ([approx] 1.8x) are observed in SSDOI compared to unstrained SOI for body thicknesses above 3.5 nm. The mobility exhibits a sharp drop as the body thickness is scaled below 3.5 nm.
by Leonardo Gomez.
S.M.
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Oliveira, Glaucio Araújo de. "Dificuldades na implantação da lei de modernização dos portos no Brasil : o caso do Porto de Paranaguá / Glaucio Araújo de Oliveira ; orientação, Carlos Frederico Marés de Souza Filho." reponame:Biblioteca Digital de Teses e Dissertações da PUC_PR, 2001. http://www.biblioteca.pucpr.br/tede/tde_busca/arquivo.php?codArquivo=16.
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Dissertação (mestrado) - Pontifícia Universidade Católica do Paraná, 2001Inclui bibligrafias
Aborda as dificuldades na implantação da Lei de Modernização dos Portos, como tema central. O método utilizado para o desenvolvimento da pesquisa esta afeto a situação fática da Administração dos Portos de Paranaguá e Antonina (APPA), imiscuindo-se, inclu
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Martinez, Derek Luberli. "Palmitoylation and Oxidation of the Cysteine Rich Region of SNAP-25 and their Effects on Protein Interactions." BYU ScholarsArchive, 2007. https://scholarsarchive.byu.edu/etd/985.
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Neurons depend upon neurotransmitter release through regulated exocytosis to accomplish the immense processing performed within the central nervous system. The SNARE hypothesis points to a family of proteins that are thought to enable the membrane fusion that leads to exocytosis. The secondary structure of SNAP-25 is unique among SNARE proteins in that it has two alpha helical SNARE motifs and a cysteine rich (C85, C88, C90, C92) membrane interacting region but notransmembrane domain. The cysteines may be modified by palmitoylation or oxidation but the role of these modifications in vivo is not well understood. Our goal is to elucidate possible regulatory roles of SNAP-25 that relate to its unique structure and these reversible modifications. However, the study of SNAP-25 in reconstituted systems is hampered by a lack of readily available palmitoylated SNAP-25. A method for in vitro palmitoylation of SNAP-25 by HIP14, a neuronal acyltransferase, is described along with the application of a biotinylation streptavidin assay to verify palmitoylation. Palmitoylation increases the extent to which SNAP-25 interacts with lipids as observed with an environment sensitive trpytophan fluorescence assay. Palmitoylation also alters the phase transition of DPPC lipids differently than unpalmitoylated SNAP-25.This effect on the membrane may influence fusion events. Oxidation of the cysteine residues may be responsible for the sensitivity of SNAP-25 to reactive oxygen species. Our data suggests that, when oxidized, SNAP-25 does not interact with membranes to the same extent as palmitoylated SNAP-25. This may provide a mechanism for reducing exocytosis during oxidative stress. Also, oxidized SNAP-25 is not susceptible to Botulinum Neurotoxin E. The effects of oxidation and palmitoylation on the protein interactions of SNAP-25 may shed light on its role in the SNARE complex and membrane fusion.
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Kiprop, Ambrose Kipchumba. "Synthèse et caractérisation des acides fulviques dans des systèmes C-H-O, C-H-O-N et C-H-O-N-S : Etude spectroscopique UV-visible des complexes uranyle (VI)-fulvate en fonction du pH, à 25 degrés C et 1 bar." Thesis, Nancy 1, 2009. http://www.theses.fr/2009NAN10094/document.
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Des acides fulviques contenant éléments (1) C,H,O, (2) C,H,O,N et (3) C,H,O,N,S chimiques ont été synthétisés à partir de réactions dans quatre mélanges de composés chimiques purs : (1) C6H4(OH)2 + NaOH, (2) C6H4(OH)2 + CH3COOH +NaOH, (3) C6H4(OH)2 + NH2CH2COOH + NaOH et (4) C6H4(OH) 2 + NH2CH(CH2SH)COOH + NaOH, à pH = 10,0, à l’abri de la lumière et dans des conditions expérimentales proches de celles de la nature (température ambiante, f et f O2 ( g ) CO2 ( g ) atmosphériques). Des analyses qualitatives et semi-quantitatives des acides fulviques de synthèse (AFS) à l’aide d’une combinaison de techniques d'analyse en microscopie électronique, en spectrométrie moléculaire (FTIR-ATR, UV-visible, ESI-MS, APCI-MS) et en diffraction des rayons X ont permis d'obtenir les résultats suivants: - les quatre mélanges réactionnels ont produit un nombre important d'acides fulviques individuels, dont les rapports m/z pouvant atteindre une valeur maximale de 943 et sont amorphes; - les AFS comportent groupements fonctionnels: alcool, éther et carboxylate. L’introduction de composés tels que CH3COOH, NH2CH2COOH et NH2CH(CH2SH)COOH se traduit par d´acides fulviques contenant respectivement des groupements fonctionnels ester, amine et thiol. Enfin, une étude systématique des interactions entre l´ion U(VI) et des ligands fulvate contenant trois éléments (C,H,O) en fonction du pH (4 – 10) a été développée à l'aide de la spectroscopie UV-visible. Deux types de complexes U(VI)-fulvate ont été formés à pH = 4 - 7 et trois types de complexes à pH = 10. La présenc e de bandes d'absorption larges montrent que des ions polyuranyle (VI) participent à ces complexes U(VI) - fulvateFulvic acids containing chemical elements (1) C,H,O, (2) C,H,O,N and (3) C,H,O,N,S have been synthesized from reactions in four mixtures of pure chemical reactants: (1) C6H4(OH)2 + NaOH, (2) C6H4(OH)2 + CH3COOH +NaOH, (3) C6H4(OH)2 + NH2CH2COOH + NaOH and (4) C6H4(OH)2 + NH2CH(CH2SH)COOH + NaOH, at pH = 10.0, in the dark and under oxidative conditions close to those encountered in the nature (ambient temperature and atmospheric conditions, f and f ) O2 ( g ) CO2( g ). Qualitative and semi-quantitative analysis of synthesized fulvic acids (SFA) using a combination of analytical techniques in electron microscopy, molecular spectrometry (ATR-FTIR, UV-visible, ESI-MS, APCI-MS), and X-ray diffraction have allowed to obtain the following results : - all four reaction mixtures have produced a large number of individual fulvic acids, whose m/z ratios can be as high as 943 and are amorphous; - the SFA contain functional groups: alcohol, ether and carboxylate. The addition of compounds such as CH3COOH, NH2CH2COOH and NH2CH(CH2SH)COOH led to fulvic acids containing respectively ester, amine and thiol functional groups. Finally, a systematic study of the interactions between the U(VI) ion and fulvate ligands containing three elements (C,H,O) as a function of pH (4 – 10) has been developed using UV-visible spectroscopy. Two types of U(VI)-fulvate complexes have been identified in pH range 4 – 7 and three types of complexes at pH = 10. The presence of absorption broadbands indicates that polyuranyl (VI) ions are part of constituents of the U(VI) - fulvate complexes
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GANGEMI, Nelson Luiz. "N??vel de ader??ncia das pr??ticas cont??beis dos passivos contingentes ao CPC 25: uma an??lise das empresas sucroalcooleiras do estado de S??o Paulo." FECAP, 2016. http://tede.fecap.br:8080/jspui/handle/jspui/714.
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The adherence to the rules of recognition, measurement and disclosure of information in the explanatory notes, provides greater reliability in the presentation of financial statements to users for analysis and decision making. The accounting rules, correlated to international Standards, were issued by the CPC and one of them was the Technical pronouncement, the CPC 25, which deals with the provisions and contingent liabilities and contingent assets. The contingent liability is an obligation of accounting difficult to recognition and measurement in view of the factors of uncertainty about the confirmation or not of their existence. In this context, this work had as main objective to know and analyze the criteria for the recognition, measurement and disclosure of information in the explanatory notes of the contingent liabilities (CPC 25), through a sample 17 companies corporations, capital opened and closed the sugarcane-ethanol sector in the State of S??o Paulo. The line of research was descriptive with qualitative and quantitative approach. The procedure used for data collection was the documentary research of primary and secondary sources and was motivated by its accessibility. Was analyzed a set of financial statements published annual with explanatory notes and published without explanatory notes, in the period between 2011 and 2015. The results obtained with the sample suggest that companies since segment not yet follow fully to what is required by the legislation in relation to criteria for recognition and disclosure of contingent natures and their respective content, demonstrating weakness in the context of dissemination of contingent information. These results are consistent with national and international studies conducted in other segments, which revealed low practice of disclosure and disclosure of contingent liabilities, especially the environmental.
A ader??ncia pelas normas de reconhecimento, mensura????o e divulga????o das informa????es em notas explicativas, possibilita maior confiabilidade na apresenta????o das demonstra????es cont??beis aos usu??rios para an??lise e tomada decis??o. As normas cont??beis, correlacionadas ??s normas internacionais, foram emitidas pelo CPC e uma delas foi o Pronunciamento T??cnico, o CPC 25, que disp??e sobre as provis??es e passivos e ativos contingentes. O passivo contingente ?? uma obriga????o cont??bil de dif??cil reconhecimento e mensura????o tendo em vista os fatores de incertezas sobre a confirma????o ou n??o de sua exist??ncia. Neste contexto, este trabalho teve como principal objetivo conhecer e analisar os crit??rios de reconhecimento, mensura????o e divulga????o das informa????es em notas explicativas dos passivos contingentes (CPC 25), mediante uma amostra 17 empresas sociedades an??nimas, de capital aberto e fechado do segmento sucroalcooleiro do Estado de S??o Paulo. A linha da pesquisa teve car??ter descritivo com abordagem qualitativa e quantitativa. O procedimento utilizado para coleta de dados foi pela pesquisa documental de fontes prim??rias e secund??rias e foi motivada pela sua acessibilidade. Foi analisado um conjunto de demonstra????es cont??beis anuais publicadas com notas explicativas e publicadas sem notas explicativas, no per??odo entre 2011 e 2015. Os resultados alcan??ados com a amostra sugerem que as empresas desde segmento ainda n??o seguem plenamente ao que ?? exigido pela normativa frente aos crit??rios de reconhecimento e divulga????o das naturezas contingentes e seus respectivos conte??dos, demonstrando fragilidade no contexto da divulga????o das informa????es contingentes. Estes resultados v??o de encontro com estudos nacionais e internacionais realizados em outros segmentos, que revelou baixa pratica de evidencia????o e divulga????o dos passivos contingentes, principalmente os ambientais.
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Khmeleva, Elena A. "El tríptico tolstoyano de Doña Emilia Pardo Bazán." Miami University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=miami1242252787.
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White, Carolyn R. "Dominicanidad: raza, religión, y poder en una isla dividida." Ohio University Honors Tutorial College / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ouhonors1276733973.
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Romero, Ccarhuarupay Mari Carmen, Salgado Ridson Warthon, Blanco Felmar Nimrod Secca, Aquino Ribert Cristhian Payva, and Valer Ruben Vera. "Beneficios de Construir Edificaciones multifamiliares con Certificación EDGE en la zona 3 del distrito de Cusco, en base a los bonos de la Ordenanza Municipal N° 25-2019-MPC." Master's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2020. http://hdl.handle.net/10757/655679.
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En la actualidad y desde hace algunos años, se viene tomando más conciencia por el cuidado del medio ambiente, esto debido a los efectos adversos que generan sobre la humanidad y por sobre todo debido a que representa a su vez una oportunidad de mejora y con ello una oportunidad de negocio también. Es así como existen diversas iniciativas, normativas públicas y privadas, que promueven la disminución del impacto ambiental en diferentes rubros que van desde lomas simple como reutilizar papel en una oficina, hasta inclusive realizar elaboradas construcciones o edificios sostenibles.
En ese sentido, en el sector Construcción en nuestro país existen diversas normativas estatales que ayudan al control ambiental desde la concepción de un proyecto, y sobre todo en la etapa de construcción, pero no se enfocan en el cuidado ambiental a futuro, es decir durante la operación, debido entonces a estas ausencias estatales, existen también iniciativas privadas como las Certificaciones que promueven la Construcción de edificios Sostenibles (EDGE, LEEG, BREAM, entre otras).
Estas Certificaciones no solo promueven el uso de materiales y equipos que, en primera instancia sean de bajo impacto ambiental, sino que también durante su operación permitan un uso moderado del consumo de agua y energía, lo cual si bien es cierto puede elevar el costo de construcción, a su vez es claro que permite reducir los costos operativos; justamente el objetivo del presente trabajo de investigación es analizar el costo - beneficio de una edificación sostenible en la ciudad del Cusco, específicamente usando parámetros de la Certificación EDGE respecto a una edificación de concepción tradicional.
Parte importante para fomentar el desarrollo de proyectos sostenible radica en iniciativas locales, las cuales y mediante Ordenanzas Municipales promueven la Construcción de Edificios sostenibles, claro está que logren obtener una certificación, otorgando bonificaciones de altura a los promotores inmobiliarios, de tal forma se tenga un mayor área vendible, este es el caso de ordenanza Municipal N° 025-2019-MPC de la Municipalidad Provincial de Cusco, donde se ubica nuestro caso de Estudio Edificio multifamiliar Amauta III.Nowadays and for some years, more awareness has been taken about caring for the environment, this due to the adverse effects that generated on humanity and above all because it represents in turn an opportunity for improvement and also with it a business opportunity too. There are various initiatives and regulations even public and privates that promote the reduction of environmental impact, some of them can be as simple as reusing paper in an-office, some others can be to even making elaborate constructions or sustainable buildings. In this sense, in the construction sector in our country there are various laws and regulations that help environmental control from the conception of a project, and especially in the construction process, but almost all of them are not focused on future environmental care, that is, during The operation, then due to these state absences, there are also private initiatives such as Certifications that promote the Construction of Sustainable buildings such us EDGE, LEEG, BREAM, among others These Certifications not only promote the use of materials and equipment that, in the first instance, have low environmental impact, but also during their operation stage allow a moderate use of water and energy consumption, which, although it is true, can raise the cost of construction, in turn, it is clear that it allows reducing operating costs; precisely the objective of this research work is analyze the cost - benefit of a sustainable building in the city of Cusco, specifically using parameters of the EDGE Certification with respect to a building of traditional conception. An important part to promote the development of sustainable buildings lies in local initiatives, which and through Municipal Ordinances promote the Construction of Sustainable Buildings, of course they manage to obtain a certification, granting height bonuses to real estate developers, in such a way that they have a largest salable area, this is the case of Municipal Order No. 025-2019-MPC of the Provincial Municipality of Cusco, where our case of Study Amauta III multifamily building is located.
Tesis
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HEDHILI, MOHAMED NEJIB. "Dynamique de desorption d'ions stimulee par impact d'electrons de basse energie (0 - 25 ev) sur les molecules o 2, n 2o et cf 4 condensees sur des substrats metalliques." Paris 6, 1998. http://www.theses.fr/1998PA066733.
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L'interaction d'electrons de basse energie (0 - 25 ev) avec des molecules condensees conduit a la desorption d'ions negatifs et positifs dont les spectres de rendement et les distributions d'energie cinetique permettent de decrire les mecanismes et la dynamique des processus en jeu. Des etudes sur les molecules o 2, n 2o et cf 4 condensees sur un metal (pt) montrent que les mecanismes (l'attachement dissociatif et la dissociation dipolaire) et la dynamique de desorption dependent des conditions de condensation. - en multicouches de molecules d'oxygene o 2, la formation de resonances o - * 2 de symetrie +, interdites en phase gazeuse, contribue a la desorption d'ions o - et que la predissociation d'etats de rydberg o * 2 est responsable de la desorption d'ions o - et o + via le processus de dissociation dipolaire. - en monocouche ou submonocouche de o 2, un processus de desorption d'ions o - tres energetiques impliquant un transfert de charge du substrat metallique vers des fragments neutres o formes par excitation dissociative par impacts d'electrons sur o 2 condense est mis en evidence. - des distributions d'energie cinetique d'ions o - montrent que la dynamique de desorption depend de l'environnement dans lequel les molecules o 2 sont condensees et qu'en plus des collisions multiples des electrons incidents et des ions, les phenomenes de fluctuation de l'energie de polarisation et de creation de phonons dans le substrat et le milieu condense jouent un role important. - enfin l'interaction d'electrons avec l'oxygene moleculaire condense conduit a la production d'ozone o 3 en surface et en volume de l'adosorbat via des reactions atomes-molecules, avec un seuil a 3. 5 ev d'energie incidente.
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Lee, Ann-Gee. "Female Fabrications: An Examination of the Public and Private Aspects of Nüshu." Bowling Green State University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1225660015.
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Zimmer, Karine Rigon. "Atividade antibiofilme e antibiótica da cera dos ovos e de metabólitos produzidos por bactérias associadas ao carrapato Rhipicephalus (Boophilus) microplus." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2012. http://hdl.handle.net/10183/69694.
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A oviposição é um estágio vulnerável do ciclo de vida de carrapatos. Rhipicephalus microplus, como todos Ixodidae e Argasidae, possui uma glândula especializada, o órgão de Gené, que produz uma cera que é depositada na superfície do ovo durante a oviposição. Além de restringir a perda excessiva de água, a cera atua como uma barreira contra o ataque de organismos invasores. Em R.microplus, como em outros carrapatos, há poucos estudos demonstrando atividade antimicrobiana em ovos. Ainda mais, não há na literatura relato de atividade antibiofilme em ovos de carrapatos e nem mesmo em qualquer outro artrópode. O objetivo do presente trabalho foi avaliar a hipótese da existência de mecanismos de defesa em ovos de R. microplus contra biofilmes bacterianos. O extrato água/metanol da cera dos ovos apresentou atividade contra o biofilme de Pseudomonas aeruginosa sem afetar a sua viabilidade. Esse extrato também demonstrou efeito antibiótico contra Staphylococcus epidermidis. Nós identificamos a molécula com ambas atividades (antibiofilme e antibiótica) como N-(3-sulfooxy-25-cholest-5-en-26-oyl)-L-isoleucina (boophiline). Na busca por possíveis mecanismos responsáveis pelo efeito antibiofilme de boophiline contra P. aeruginosa, 14 genes foram analisados por qRT-PCR. Boophiline inibe a expressão de fliC (flagelo) e cdrA (componente estrutural da matriz), cujos produtos são necessários para a formação do biofilme de P. aeruginosa. Monosfosfato de guanosina dimérico cíclico (c-di-GMP) é um importante segundo mensageiro característico de bactérias Gram-negativas. Altos níveis intracelulares de c-di-GMP promovem o estilo de vida séssil enquanto baixos níveis induzem o comportamento móvel. De acordo com essa afirmação, nós encontramos que boophiline aumenta a motilidade swarming de P. aeruginosa. Desta forma, nos questionamos se o mecanismo de ação de boophiline estaria envolvido com c-di-GMP já que o sistema quorum sensing não foi afetado pela molécula. Interessantemente, quando os níveis de c-di-GMP foram aumentados pela superexpressão de uma diguanilato ciclase, boophiline não inibiu efetivamente a formação de biofilme. Uma explicação para esse resultado é que boophiline interfere em uma via específica regulada por c-di-GMP, o que explicaria não termos obtido um decréscimo no nível total deste segundo mensageiro. Contrariamente, boophiline foi bactericida contra S. epidermidis. Mudanças morfológicas significativas foram observadas em células tratadas com a molécula, as quais foram severamente danificadas. Boophiline levou a formação anormal de septo, rompimento da membrana bacteriana e extravasamento do material intracelular. Adicionalmente avaliamos o potencial antibiofilme e anti-protozoário de filtrados de cultura obtidos de bactérias isoladas de tecidos de R. microplus. Quatorze filtrados de cultura bacteriano apresentaram notável atividade contra o biofilme de P. aeruginosa e S. epidermidis e foram citotóxicos contra Tritrichomonas foetus. Nosso trabalho é pioneiro em demonstrar a existência de proteção contra biofilmes em ovos de carrapatos bem como de bactérias associadas a carrapatos como produtoras de moléculas bioativas. Além disso, nós demonstramos que boophiline é uma nova molécula antibiofilme, sendo a primeira vez relatado na literatura que um composto age inibindo cdrA. Os dados obtidos em nosso estudo poderiam estimular novas abordagens em áreas como fisiologia e controle de artrópodes, genética e fisiologia de microrganismos e controle de biofilmes.The oviposition is a vulnerable stage of the tick life cycle. Rhipicephalus microplus, as all Ixodidae and Argasidae, has a specialized gland, the Gene’s organ, which produce a wax that is smeared on egg surface during oviposition. In addition to restricting excessive water loss, wax acts as a barrier to attack by invading organisms. In R. microplus, as in other ticks, there are few studies showing antimicrobial activity in eggs. Moreover, there is no report of antibiofilm activity in tick eggs nor in any other arthropod. The objective of our study was to evaluate the hypothesis of the existence of defense mechanisms against bacterial biofilms in R. microplus eggs. The eggs wax water/methanol extract showed activity against Pseudomonas aeruginosa biofilm without affecting its viability. This extract also presented an antibiotic effect against Staphylococcus epidermidis. We have identified the molecule anti-biofilm and antibiotic as N-(3-sulfooxy-25-cholest-5-en-26-oyl)-L-isoleucine (boophiline). In the search for possible mechanisms responsible by antibiofilm effect of boophiline against P. aeruginosa, 14 genes were evaluated by qRT-PCR. We showed that boophiline inhibits the expression of fliC (flagellum) and cdrA (matrix structural component), whose products are necessary for biofilm formation in P. aeruginosa. Bis-(3’–5’)-cyclic dimeric guanosine monophosphate (c-di-GMP) is an important second messenger, characteristic of Gram-negative bacteria. High intracellular levels of c-di-GMP promote a sessile mode of growth, while low levels promote motile behavior. In line with this, we found that boophiline increases swarming motility, which raised the question whether it acts by altering c-di-GMP levels. Interestingly, when c-di-GMP levels were increased by overexpression of a diguanilate cyclase, boophiline no longer inhibited biofilm formation. One explanation for these results is that boophiline interferes with a specific c-di-GMP-regulated pathway, which would explain we have not obtained a decrease in the total level of this second messenger. Conversely, boophiline had a bactericidal effect against S. epidermidis. Significant morphological changes were observed in the boophiline-treated cells, which appeared to be severely damaged. Boophiline was found to cause abnormal septum formation, bacterial membrane disruption, and extravasation of intracellular material. Additionally, our work also aimed to evaluate the potential antibiofilm and anti-protozoa of culture filtrates obtained from bacteria isolated of R. microplus tissues. Fourteen bacterial culture filtrates showed remarkable activity against of P. aeruginosa and S. epidermidis biofilms, and were cytotoxic against Tritrichomonas foetus. Our work is pioneer in demonstrating the existence of protection mechanisms in tick eggs against biofilms, and ticks-associated bacteria as producers of bioactive molecules. Furthermore, we demonstrated that boophiline is a new antibiofilm molecule, and is the first reported in the literature that a molecule inhibits cdrA. The data obtained in our study could stimulate new approaches in areas such as the physiology and control of arthropods, the genetics and physiology of microorganisms, and biofilm control.
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Veyrat-Durebex, François Pierre. "Influences economiques sur le droit des successions dans son elaboration depuis 1804 : analyse comparative des metasources économiques et non-économiques." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSE3015.
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Au commencement, il y a le constat, en ce début de XXIe siècle, de l'influence de la sphère économique sur la refonte de la matière successorale. Certes, cela n'est pas officiel. Dans le cadre de l'élaboration de la loi n° 2006-728 du 23 juin 2006 réformant le droit des successions et des libéralités, le législateur préfère mettre en exergue des objectifs généraux ; il est question de « simplifier », d’« accélérer » et de « sécuriser » les règlements successoraux. Si tout cela semble bien transparent de prime abord, en réalité, derrière cette « profession de foi un peu courte », se cachent des objectifs de nature économique qui traversent l'ensemble de la réforme. On peut immédiatement en citer un à titre d’exemple : celui de la survie de l’entreprise au décès de son exploitant. Cet objectif transparaît sans difficulté ; il suppose de faciliter la transmission de l’unité économique, […], mais également d'assurer la continuité de la gestion de celle-ci, […].[…] Plus avant, la dialectique suivie par le législateur du XXIe siècle n'est pas seulement celle d'une adaptation des normes juridiques aux réalités économiques contemporaines ; elle est aussi celle d'une promotion de ces normes comme instruments de compétitivité de l'économie nationale. La légistique est désormais conçue comme un vecteur dopant de la conjoncture. […] Multiplier les échanges, relancer la croissance, mettre en valeur le patrimoine économique français : ce sont là certaines des nouvelles valeurs du droit des successions, au sens de la loi du 23 juin 2006. Pour autant, cette influence de la sphère économique est-elle complètement nouvelle ? Ne sommes-nous pas en présence de l'aboutissement, ou du prolongement, d'un phénomène ancien ? On peut en effet songer que les codificateurs étaient déjà soucieux d'adapter notre ancien droit français à l'avènement de la proto-industrie, ainsi qu’au développement d'une économie d'échanges ; dans le même sens, on doit bien constater que la loi n° 71-523 du 3 juillet 1971 ne réalise, pour l'essentiel, qu’une adaptation des règles liquidatives aux fluctuations monétaires de l'après-guerre. Sans entrer plus avant dans les détails, on perçoit immédiatement en quoi ces interrogations nous portent vers la présente étude : une analyse comparative des métasources « économiques » et « non économiques », sur le thème de l'influence de la sphère économique sur le droit des successions dans son élaboration depuis 1804To start with, we can notice that at the beginning of the twenty-first century, the economic sphere is already clearly influencing the inheritance rules modification process. Admittedly, this is not an official statement. Writing the law n ° 2006-728 of June 23, 2006 which aims to reform the inheritances and liberalities regulations, the legislator prefers to highlight general objectives. This is a question of "simplifying", "speeding up" and "securing" the inheritance law. If all of this may seem very transparent at first glance, in reality, behind this "a little short profession of faith", there are some hidden economic objectives that cross the whole reform. The simplest example to cite is the survival of a company at the death of its manager. This objective is easily visible; it helps to facilitate the transmission of the economic unit, [...], but also to ensure its management continuity [...]. [...] Further, the dialectics followed by the legislator of the twenty-first century are not only for adaptation of legal norms to contemporary economic realities, but also for promoting these standards as instruments to increase the national economy's competitiveness. Legislation is now conceived as a driving force for the economic situation. [...] Multiplying trade, relaunching growth, enhancing French economic patrimony: these are some of the new values of inheritance regulations, as defined by the law of 23 June 2006. However, is this influence of the economic sphere entirely new or not ? Perhaps, we are dealing with culmination or prolongation of an old phenomenon ? We may indeed think that the legislators have already been concerned with adapting our old French law to the advent of proto-industry, as well as to the development of the trading economy ; in the same sense, it should be noted that, for the most part, the law n° 71-523 of July 3d, 1971 has done nothing more than making an adjustment of the liquidation rules to the monetary fluctuations of the post-war period. Without going further into the details, we can immediately notice how these questions lead us to the present study : a comparative analysis of "economic" and "non-economic" metasources, on the subject of influence of the economic sphere on the inheritance rights in its development since 1804
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Bejarano, Roberto Villa. "An Investigation Into| I) Active Flow Control for Cold-Start Performance Enhancement of a Pump-Assisted, Capillary-Driven, Two-Phase Cooling Loop II) Surface Tension of n-Pentanol + Water, a Self-Rewetting Working Fluid, From 25 ?C to 85 ?C." Thesis, University of Nevada, Reno, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=1565813.
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Cold-start performance enhancement of a pump-assisted, capillary-driven, two-phase cooling loop was attained using proportional integral and fuzzy logic controls to manage the boiling condition inside the evaporator. The surface tension of aqueous solutions of n-Pentanol, a self-rewetting fluid, was also investigated for enhancing heat transfer performance of capillary driven (passive) thermal devices was also studied. A proportional-integral control algorithm was used to regulate the boiling condition (from pool boiling to thin-film boiling) and backpressure in the evaporator during cold-start and low heat input conditions. Active flow control improved the thermal resistance at low heat inputs by 50% compared to the baseline (constant flow rate) case, while realizing a total pumping power savings of 56%. Temperature overshoot at start-up was mitigated combining fuzzy-logic with a proportional-integral controller. A constant evaporator surface temperature of 60°C with a variation of ±8°C during start-up was attained with evaporator thermal resistances as low as 0.10 cm2–K/W. The surface tension of aqueous solutions of n-Pentanol, a self-rewetting working fluid, as a function of concentration and temperature were also investigated. Self-rewetting working fluids are promising in two-phase heat transfer applications because they have the ability to passively drive additional working fluid towards the heated surface; thereby increasing the dryout limitations of the thermal device. Very little data is available in literature regarding the surface tension of these fluids due to the complexity involved in fluid handling, heating, and experimentation. Careful experiments were performed to investigate the surface tension of n-Pentanol + water. The concentration and temperature range investigated were from 0.25%wt. to1.8%wt and 25°C to 85°C, respectively.
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Maturrano, Ascencio Christian Joseph. "Valor diagnóstico del radiorrenograma con DTPA-TC99m para la estimación de tasa de filtración glomerular en relación a la ecuación de cockroft gault en pacientes mayores de 25 años con enfermedad renal crónica hospital Central PNP Luis N. Sáenz en el periodo marzo – mayo 2015." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2015. https://hdl.handle.net/20.500.12672/4326.
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I Objetivos.- Determinar el valor diagnostico del estudio de Radiorrenograma con Dtpa – Tc99m para estimar la tasa de filtración glomerular en pacientes con enfermedad renal crónica en el Hospital Central de la Policía Nacional del Perú “Luis N. Sáenz. Diseño: Estudio observacional, descriptivo, prospectivo y de corte transversal. Institución:”; Lima, Perú. Materiales: Historias Clínicas.
II Intervenciones.- estudio de historias clínicas de pacientes con una muestra poblacional, no probabilístico. De los cuales por no cumplir con los criterios de inclusión quedaron un total de 34 historias clínicas, siendo estos 20 de sexo masculino y 14 de sexo femenino los cuales se encuentran dentro de un rango de edad, de 25 años a más. La muestra se obtuvo revisando cada historia clínica, estos presentaban un informe de laboratorio con la filtración glomerular y la orden de estudio de Radiorrenograma con DTPA-Tc99m entre el periodo marzo-mayo del 2015.
III Principales medidas de resultados.- Sensibilidad, especificidad, valor predictivo positivo y negativo del Radiorrenograma con DTPA-Tc99m para la estimación de filtración glomerular. Resultados: con los datos recabados, se calculó el valor diagnostico del Radiorrenograma con DTPA-Tc99m para la estimación de filtración glomerular. La sensibilidad del Radiorrenograma con DTPA-Tc99m es de 69.23% (IC 95%,40.30% al 98.17%); una especificidad de 90.48% (IC 95%, 75.54% al 100%); un valor predictivo positivo de 81.82%( IC 95%,54.48% al 100%) y un valor predictivo negativo de 82.61% (IC 95%,64.94% al100%) para la estimación de filtrado glomerular.
IV Conclusiones.- El Radiorrenograma con DTPA-Tc99m es el estudio isotópico adecuado para la estimación de filtración glomerular en la enfermedad renal crónica.I. Purpose -. To determine the diagnostic value of Radiorrenograma with DTPA-Tc99m studying, to estimate glomerular filtration rate in patients with chronic kidney disease at Central Hospital of the National Police of Peru " Luis N. Sáenz. Design: Observational, descritptive, porspective and cross-sectioanl study. Institution: Central Hospital of the National Police of Peru "Luis N. Sáenz, Lima, Peru. Materials: Medical Records II. interventions.- study of medical records of patients with a sample population, which no probabilistic. Of which not meet the inclusion criteria were a total of 34 medical records, and these 20 males and 14 females who are within an age range of 25 years more The sample was obtained bye reviewing medical recods each, they presented a report of the laboratory test with glomerular flitration and the order of study of Radiorrenograma with DTPA-Tc99m between the period March – may 2015 III. Main outcome measures-. Sentitivity, specificity, positive an negative predictive value of Radiorrenograma with DTPA-Tc99m for estimating glomerular filtration. Results: With the data collected; the diagnostic value of Radiorrenograma with DTPA-Tc99m for estimating glomerular filtration was calculated.Radiorrenograma with DTPA-Tc99m sensitivy is 69.23 % (95% CI, 40.30% to 98.17%); a specificity of 90.48 % (95% CI, 75.54% to 100%); a positive predictive value of 81.82 % (95% CI, 54.48% to 100%) and negative predictive value of 82.61 % (95% CI, 64.94 % al 100%) for estimating glomerular filtration. IV. Conclusions -. The Radiorrenograma with DTPA - Tc99m is right isotopic study for estimating GFR in chronic renal disease. Keywords: Radiorrenograma; DTPA – Tc99m; glomerular filtration; Chronic kidney diseas
Tesis
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Gazda, Emily. "Los niños que se quedan atrás: la doble moral sobre el bilingüismo de los niños de lengua minoritaria en las escuelas públicas estadounidenses = The children left behind: the double standard of bilingualism for minority language c." Oberlin College Honors Theses / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=oberlin1336696910.
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Pinto, Veas Diego Alfonso. "Estado y pobladores en la configuración del territorio: — del campamento Nueva Habana a Población Nuevo Amanecer : territorialidad de los habitantes y configuración espacial generada por las políticas habitacionales implementadas por el Estado de Chile 1970-2009 : Unidad Vecinal N° 25 (Nuevo Amanecer), Comuna de La Florida." Tesis, Universidad de Chile, 2012. http://www.repositorio.uchile.cl/handle/2250/100484.
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Tang, Ling-Xiang. "Link discovery for Chinese/English cross-language web information retrieval." Thesis, Queensland University of Technology, 2012. https://eprints.qut.edu.au/58416/1/Ling-Xiang_Tang_Thesis.pdf.
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Nowadays people heavily rely on the Internet for information and knowledge. Wikipedia is an online multilingual encyclopaedia that contains a very large number of detailed articles covering most written languages. It is often considered to be a treasury of human knowledge. It includes extensive hypertext links between documents of the same language for easy navigation.
However, the pages in different languages are rarely cross-linked except for direct equivalent pages on the same subject in different languages. This could pose serious difficulties to users seeking information or knowledge from different lingual sources, or where there is no equivalent page in one language or another.
In this thesis, a new information retrieval task—cross-lingual link discovery (CLLD) is proposed to tackle the problem of the lack of cross-lingual anchored links in a knowledge base such as Wikipedia. In contrast to traditional information retrieval tasks, cross language link discovery algorithms actively recommend a set of meaningful anchors in a source document and establish links to documents in an alternative language. In other words, cross-lingual link discovery is a way of automatically finding hypertext links between documents in different languages, which is particularly helpful for knowledge discovery in different language domains.
This study is specifically focused on Chinese / English link discovery (C/ELD). Chinese / English link discovery is a special case of cross-lingual link discovery task. It involves tasks including natural language processing (NLP), cross-lingual information retrieval (CLIR) and cross-lingual link discovery.
To justify the effectiveness of CLLD, a standard evaluation framework is also proposed. The evaluation framework includes topics, document collections, a gold standard dataset, evaluation metrics, and toolkits for run pooling, link assessment and system evaluation. With the evaluation framework, performance of CLLD approaches and systems can be quantified.
This thesis contributes to the research on natural language processing and cross-lingual information retrieval in CLLD: 1) a new simple, but effective Chinese segmentation method, n-gram mutual information, is presented for determining the boundaries of Chinese text; 2) a voting mechanism of name entity translation is demonstrated for achieving a high precision of English / Chinese machine translation; 3) a link mining approach that mines the existing link structure for anchor probabilities achieves encouraging results in suggesting cross-lingual Chinese / English links in Wikipedia. This approach was examined in the experiments for better, automatic generation of cross-lingual links that were carried out as part of the study.
The overall major contribution of this thesis is the provision of a standard evaluation framework for cross-lingual link discovery research. It is important in CLLD evaluation to have this framework which helps in benchmarking the performance of various CLLD systems and in identifying good CLLD realisation approaches. The evaluation methods and the evaluation framework described in this thesis have been utilised to quantify the system performance in the NTCIR-9 Crosslink task which is the first information retrieval track of this kind.
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Chen, Ying-Shung, and 陳盈璇. "Characterization of proteins that interact with the N-terminal 1-252 amino acids of Cdc13p." Thesis, 2002. http://ndltd.ncl.edu.tw/handle/47545636228514471574.
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碩士國立陽明大學
生物藥學研究所
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Telomeres are guanine-rich, simple repeat sequences that constitute the physical ends of eukaryotic chromosomes. They are essential for the maintenance of chromosome integrity and protect chromosomes from degradation by nucleases. Also, they protect chromosomes from end-to-end fusions and allow their complete replication by providing a substrate for the enzyme telomerase. In addition, in Saccharomyces cerevisiae, telomeres are a specialized site for gene expression because transcription of genes near telomeres is reversibly repressed, a phenomenon called telomere position effect (TPE). Loss of telomeres could lead to cell death. In S. cerevisiae, the telomere sequence is composed of a ~350 bp of C1-3A/TG1-3 repeats plus a short single-stranded TG1-3 tail. Cdc13p is a single strand TG1-3 telomeric DNA-binding protein. It protects telomeres and regulates telomere length. Analysis of CDC13 deletion mutants found that the N-terminal 1-252 amino acids of Cdc13p are involved in telomere maintenance, cell growth, and telomere position effect. In a yeast two-hybrid screening, we found that Cdc13(1-252)p interacted with Imp4p, a catalytic subunit of DNA polymerase (Pol1p), Sir4p, and Zds2p. Sir4p is coiled-coil protein involved in maintenance of silencing of HMR, HML, and telomeres. Zds2p involved in regulation of transcriptional silencing and life span. Using in vitro protein-binding assay, we showed the direct interactions between these proteins. Moreover, co-immunoprecipitation demonstrated that endogenous Cdc13p interacted with Zds2p in vivo. Thus, it appears that telomere forms a telosomic protein-DNA complex mediated by Cdc13p. The function of Cdc13p in telomere maintenance, cell growth, and telomere position effect might through its interaction with Pol1p, Imp4p, Sir4p, and/or Zds2p.