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Academic literature on the topic 'N-022'

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Published: 25 July 2024
Last updated: 26 July 2024

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Journal articles on the topic "N-022"

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Bridge, Erica, Simron Singh, Amanda Murdoch, Mindaugas Mozuraitis, Brett Nicholls, and Lesley Moody. "Examining patient and visit characteristics associated with the cancer patient experience." Journal of Clinical Oncology 37, no. 27_suppl (September 20, 2019): 204. http://dx.doi.org/10.1200/jco.2019.37.27_suppl.204.

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204 Background: Your Voice Matters (YVM) is a 28-item patient experience survey for adult cancer outpatients undergoing treatment in Ontario.The purpose was to examine patient and visit characteristics associated with YVM responses. Methods: YVM was administered to eligible patients (n=8,704) at 14 centres in 2017.Respondents answered items on a five-point Likert scale (4 or 5 = positive response). A multivariable logistic regression (MLR) was undertaken for each YVM item.Variables (reference group) included: disease site (heamatology), age group (65+), sex (female), rurality (urban), last visit type (consult), income quintile(highest) and immigration tercile (lowest). Significant results ( p<.05) vary by MLR model. Therefore a p-value range is provided for all significant variables for all MLR models. Results: Patients were more likely to have a less positive experience if they had central nervous system ( p =.000-.013), gastrointestinal ( p =.004-.026), head and neck ( p =.002-.025), or lung cancer ( p =.017-.049); were between the ages of 18-39 years ( p = <.0001-.048); were female ( p =.0001-.022); received chemotherapy( p =.0001-.047); lived in a rural location ( p =.042); from a mid-( p =.027-.045) and mid-high income quartile ( p =.021); and in the high- ( p =.002-.043) and middle-immigrant terciles ( p =.028-.047), when compared to the reference group. Patient were more likely to have a more positive experience if they had skin cancer ( p =.004-.032); were between the ages of 40-64 years ( p =.003-.033); receiving radiation ( p =.0001-.041) or a minor procedure ( p =.015); and were from the mid-low ( p =.003-.042) and low income quartile ( p =.001-.032), when compared to the reference group. Conclusions: The cancer patient experience varies by patient and visit characteristics. Future initiatives should examine these characteristics to better understand their populations to create a more tailored approaches to cancer care.
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Myroslava I, Vovk, Pukach Petro Ya, and Prykarpatski Anatolij K. "A remark on a perturbed Benjamin-Bona-Mahony type equation and its complete integrability." Annals of Mathematics and Physics 6, no. 1 (February 14, 2023): 021–25. http://dx.doi.org/10.17352/amp.000071.

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vv 022 Citation: Vovk MI, Pukach PY, Prykarpatski AK (2023) A remark on a perturbed Benjamin-Bona-Mahony type equation and its complete integrability. Ann Math Phys 6(1): 021-025. DOI: https://dx.doi.org/10.17352/amp.000071 https://dx.doi.org/10.17352/ampDOI: M A T H E M A T I C S A N D P H Y S I C S G R O U P 2689-7636ISSN: ABSTRACT IN THE LETTER, WE STUDY A PERTURBED BENJAMIN-BONA-MAHONY NONLINEAR EQUATION, WHICH WAS DERIVED FOR DESCRIBING SHALLOW WATER WAVES AND POSSESSING A RICH LIE SYMMETRY STRUCTURE. BASED ON THE GRADIENT-HOLONOMIC INTEGRABILITY CHECKING SCHEME APPLIED TO THIS EQUATION, WE HAVE ANALYTICALLY CONSTRUCTED ITS INFINITE HIERARCHY OF CONSERVATION LAWS, DERIVED TWO COMPATIBLE POISSON STRUCTURE AND STATED ITS COMPLETE INTEGRABILITY.
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Hayhoe, Richard P. G., Marleen A. H. Lentjes, Angela A. Mulligan, Robert N. Luben, Kay-Tee Khaw, and Ailsa A. Welch. "Carotenoid dietary intakes and plasma concentrations are associated with heel bone ultrasound attenuation and osteoporotic fracture risk in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk cohort." British Journal of Nutrition 117, no. 10 (May 28, 2017): 1439–53. http://dx.doi.org/10.1017/s0007114517001180.

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AbstractCarotenoids are found in abundance in fruit and vegetables, and may be involved in the positive association of these foods with bone health. This study aimed to explore the associations of dietary carotenoid intakes and plasma concentrations with bone density status and osteoporotic fracture risk in a European population. Cross-sectional analyses (n 14 803) of bone density status, using calcaneal broadband ultrasound attenuation (BUA) and longitudinal analyses (n 25 439) of fracture cases were conducted on data from the prospective European Prospective Investigation into Cancer and Nutrition-Norfolk cohort of middle-aged and older men and women. Health and lifestyle questionnaires were completed, and dietary nutrient intakes were derived from 7-d food diaries. Multiple regression demonstrated significant positive trends in BUA for women across quintiles of dietary α-carotene intake (P=0·029), β-carotene intake (P=0·003), β-cryptoxanthin intake (P=0·031), combined lutein and zeaxanthin intake (P=0·010) and lycopene intake (P=0·005). No significant trends across plasma carotenoid concentration quintiles were apparent (n 4570). The Prentice-weighted Cox regression showed no trends in fracture risk across dietary carotenoid intake quintiles (mean follow-up time 12·5 years), except for a lower risk for wrist fracture in women with higher lutein and zeaxanthin intake (P=0·022); nevertheless, inter-quintile differences in fracture risk were found for both sexes. Analysis of plasma carotenoid data (mean follow-up time 11·9 years) showed lower hip fracture risk in men across higher plasma α-carotene (P=0·026) and β-carotene (P=0·027) quintiles. This study provides novel evidence that dietary carotenoid intake is relevant to bone health in men and women, demonstrating that associations with bone density status and fracture risk exist for dietary intake of specific carotenoids and their plasma concentrations.
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Ju, Hyerim, Shailashree Pachhapure, Amila Mufida, Aryun Kim, David R. Elmaleh, Sungwoon Choi, and Byeong-Churl Jang. "2-Aryl Propionic Acid Amide Modification of Naproxen and Ibuprofen Dimers for Anti-neuroinflammatory Activity in BV2 mouse Microglial Cells." Keimyung Medical Journal 41, no. 2 (December 15, 2022): 56–66. http://dx.doi.org/10.46308/kmj.2022.00199.

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Inflammation is a common link in the pathophysiology of many neurological illnesses, including Alzheimer’s disease. Activated glial cells contribute to neuroinflammation by producing pro-inflammatory mediators. Naproxen and ibuprofen are nonsteroidal anti-inflammatory drugs with 2-aryl(s) propionic acid as a common pharmacophore. Here we designed a small series of naproxen and ibuprofen amide dimers and tested their effects on the expression of inducible nitric oxide synthase (iNOS), a neuroinflammatory enzyme in lipopolysaccharide (LPS)-stimulated BV2 mouse microglial cells. Of note, treatment with CNU 019, 020, 021, 023, 024, and 027 at 10 M markedly inhibited the LPS-induced iNOS expression in BV2 cells. CNU 024 was tested further at different concentrations to regulate the LPS-induced iNOS expression in BV2 cells. Treatment with CNU 024 at 5, 10, or 20 M dose-dependently suppressed the LPS-induced iNOS protein and mRNA expression levels in BV2 cells, in which maximal inhibition was seen at 20 M. CNU 024 treatment at doses tested further led to a concentration-dependent inhibition of the LPS-induced phosphorylation (activation) of p38 mitogen-activated protein kinase (MAPK) without influencing its total protein expression in BV2 cells, but it did not affect the LPS-induced activation of c-jun N-terminal kinase-1/2 and extracellular signal-regulated kinases-1/2 in these cells. In summary, our results demonstrate that CNU 024 inhibits the LPS-induced iNOS expression in BV2 cells, partly mediated by the inhibition of p38 MAPK. This work shows that CNU 024 could be a valuable ligand for further development as a potential drug candidate for treating neuroinflammatory pathologies.
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Tristão Parra, Maíra, Naghmeh Esmeaeli, Jordan Kohn, Brook L. Henry, Stephen Klagholz, Shamini Jain, Christopher Pruitt, Daniel Vicario, Wayne Jonas, and Paul J. Mills. "Greater Well-Being in More Physically Active Cancer Patients Who Are Enrolled in Supportive Care Services." Integrative Cancer Therapies 19 (January 2020): 153473542092143. http://dx.doi.org/10.1177/1534735420921439.

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Background: Cancers are one of the leading causes of mortality worldwide. Cancer patients are increasingly seeking integrative care clinics to promote their health and well-being during and after treatment. Aim: To examine relationships between physical activity (PA) and quality of life (QoL) in a sample of cancer patients enrolling in integrative care in a supportive care clinic. Also, to explore circulating inflammatory biomarkers and heart rate variability (HRV) in relationship to PA and QoL. Methods: A cross-sectional design of adult patients who sought care in the InspireHealth clinic, Vancouver, British Columbia, Canada. Patients with complete PA data (n = 118) answered psychosocial questionnaires, provided blood samples, and received HRV recordings before enrollment. Patients were stratified into “less” versus “more” active groups according to PA guidelines (150 minutes of moderate or 75 minutes of vigorous PA or an equivalent combination). Results: Breast (33.1%) and prostate (10.2%) cancers were the most prevalent primary diagnoses. Patients engaging in more PA reported better physical ( U = 1265.5, P = .013), functional ( U = 1306.5, P = .024), and general QoL ( U = 1341, P = .039), less fatigue ( U = 1268, P = .014), fewer physical cancer-related symptoms ( U = 2.338, P = .021), and less general distress ( U = 2.061, P = .021). Between PA groups, type of primary cancer diagnosis differed (χ2 = 41.79, P = .014), while stages of cancer did not (χ2 = 3.95, P = .412). Fewer patients reported depressed mood within the more active group (χ2 = 6.131, P = .047). More active patients were also less likely to have ever used tobacco (χ2 = 7.41, P = .025) and used fewer nutritional supplements (χ2 = 39.74, P ≤ .001). An inflammatory biomarker index was negatively correlated with vigorous PA ( rs = −0.215, P = .022). Multivariable linear regression ( R2 = 0.71) revealed that age (β = 0.22; P = .001), fatigue (β = −0.43; P ≤ .001), anxiety (β = −0.14; P = .048), and social support (β = 0.38; P = .001) were significant correlates of QoL.
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Carré, Typhanie, Caroline Gaudy-Marqueste, Frédérique Albarel, Sandrine Monestier, Stéphanie Mallet, Thierry Brue, Marie-Aleth Richard, and Jean Jacques Grob. "Ipilimumab-induced hypophysitis in melanoma patients." Journal of Clinical Oncology 30, no. 15_suppl (May 20, 2012): 8568. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.8568.

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8568 Background: Ipilimumab (Ipi) is a human monoclonal antibody directed against cytotoxic T-lymphocyte antigene-4 (CTLA-4) recently approved for the treatment of metastatic melanoma (MM) and currently under investigation in the adjuvant setting. Methods: Retrospective analysis of patients treated with ipi between June 2006 and September 2011 in our department in Marseille. As some patients are still blinded in trials, the exact number of patient under ipi is unknown. We present a minimal percentage (>%) assuming that the 120 patients received ipi. Results: A total of 120 patients were treated: 76 stages IV MM, from which 16 in the BMS clinical trials (CA184-022, -024, and-025 and MDX 010-20) and 44 stages III MM (in the BMS CA184-029 trial). Stage IV MM were administered 0.3, 3 or 10mg/kg IV dosage, while stages III MM were randomly assigned to receive 10 mg/ kg or placebo (1:1 ratio). Hypophysitis was diagnosed in 12 patients (>10%): 2/76 patients with stage IV MM (>2. 6 %) and 10/44 patients with stage III MM (>22.7). Diagnosis was performed at the 1st, 3rd and 4th administration in respectively 2 (1.6%), 6 (50%) and 4 patients (33.3%). Clinical symptoms included headaches (n=11; 91.6%), asthenia (n=7; 58.3%) and decreased libido (n=2; 1.6%). Adrenal, thyroidal and gonadal axis were affected in respectively 6 (50%), 9 (75%) and 7 patients (58.3%). MRI changes were observed in 7 patients (58.3%): pituitary swelling in 5 patients (41.6%) and heterogeneous enhancement in 4 patients (33.3%) including 2 patients with normal biology. Corticosteroids supplementation was required in 11 patients and thyroidian supplementation in 4 patients. Clinical symptoms regressed within one week in 8 patients (66.6%). Conclusions: Ipi-induced hypophysitis is detectable only if clinicians are aware of these unspecific signs. Only MRI can make diagnosis in some patients without clinical and/or biological signs. Our data suggest that it develops especially for 10mg/kg dosage, after the third administration, and that the rate could be higher in patients with a normal immune system (adjuvant treatment), than in metastatic ones. Hormonal supplementation usually controls the disease.
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O’Brien, Eileen C., Goiuri Alberdi, Aisling A. Geraghty, and Fionnuala M. McAuliffe. "Lower education predicts poor response to dietary intervention in pregnancy, regardless of neighbourhood affluence: secondary analysis from the ROLO randomised control trial." Public Health Nutrition 20, no. 16 (August 15, 2017): 2959–69. http://dx.doi.org/10.1017/s1368980017001951.

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AbstractObjectiveTo determine if response to a low glycaemic index (GI) dietary intervention, measured by changes in dietary intake and gestational weight gain, differed across women of varying socio-economic status (SES).DesignSecondary data analysis of the ROLO randomised control trial. The intervention consisted of a two-hour low-GI dietary education session in early pregnancy. Change in GI was measured using 3 d food diaries pre- and post-intervention. Gestational weight gain was categorised as per the 2009 Institute of Medicine guidelines. SES was measured using education and neighbourhood deprivation.SettingThe National Maternity Hospital, Dublin, Ireland.SubjectsWomen (n 625) recruited to the ROLO randomised control trial.ResultsThe intervention significantly reduced GI and excess gestational weight gain (EGWG) among women with third level education residing in both disadvantaged (GI, mean (sd), intervention v. control: −3·30 (5·15) v. −0·32 (4·22), P=0·024; EGWG, n (%), intervention v. control: 7 (33·6) v. 22 (67·9); P=0·022) and advantaged areas (GI: −1·13 (3·88) v. 0·06 (3·75), P=0·020; EGWG: 41 (34·1) v. 58 (52·6); P=0·006). Neither GI nor gestational weight gain differed between the intervention and control group among women with less than third level education, regardless of neighbourhood deprivation.ConclusionsA single dietary education session was not effective in reducing GI or gestational weight gain among less educated women. Multifaceted, appropriate and practical approaches are required in pregnancy interventions to improve pregnancy outcomes for less educated women.
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Sharara-Chami, Rana, Zavi Lakissian, Randa Farha, Hani Tamim, and Nicholas Batley. "In-situ simulation-based intervention for enhancing teamwork in the emergency department." BMJ Simulation and Technology Enhanced Learning 6, no. 3 (August 19, 2019): 175–77. http://dx.doi.org/10.1136/bmjstel-2019-000473.

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Simulation-based learning activities in the emergency department (ED) improve communication and teamwork and familiarise personnel with existing protocols. The authors’ objective was to develop standardised in-situ simulations and to assess their effects on team performance during simulated patient care. The study was a prospective, single-centre pre-in-situ and post-in-situ simulation-based intervention in the ED of an academic hospital between March 2017 and February 2018. Teams of three to five participants (n=46) were in two simulation interventions 2 weeks apart; each simulation was followed by debriefing with good judgement. The adapted Simulation Team Assessment Tool (STAT) Score was the primary measure for team performance. Skills are measured on a scale of 2–0 based on the complete and timely performance of tasks for a total (adapted) score of 171. Overall STAT scores improved significantly between simulations I (60.5 (28.3)) and II (81.1 (24.6)), p=029; notably in airway and teamwork domains, p=022 and p=023, respectively. A sub-analysis showed that participants performed significantly better when treating adult versus paediatric simulated patients (87.9 (20.1)), p=003, particularly in teamwork, p=01. The study yielded statistically significant improvement in clinical management, teamwork and resource management skills among ED personnel.
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Galvão, Daniel A., Dennis R. Taaffe, Nigel Spry, David Joseph, and Robert U. Newton. "Combined Resistance and Aerobic Exercise Program Reverses Muscle Loss in Men Undergoing Androgen Suppression Therapy for Prostate Cancer Without Bone Metastases: A Randomized Controlled Trial." Journal of Clinical Oncology 28, no. 2 (January 10, 2010): 340–47. http://dx.doi.org/10.1200/jco.2009.23.2488.

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Purpose Androgen suppression therapy (AST) results in musculoskeletal toxicity that reduces physical function and quality of life. This study examined the impact of a combined resistance and aerobic exercise program as a countermeasure to these AST-related toxicities. Patients and Methods Between 2007 and 2008, 57 patients with prostate cancer undergoing AST (commenced > 2 months prior) were randomly assigned to a program of resistance and aerobic exercise (n = 29) or usual care (n = 28) for 12 weeks. Primary end points were whole body and regional lean mass. Secondary end points were muscle strength and function, cardiorespiratory capacity, blood biomarkers, and quality of life. Results Analysis of covariance was used to compare outcomes for groups at 12 weeks adjusted for baseline values and potential confounders. Patients undergoing exercise showed an increase in lean mass compared with usual care (total body, P = .047; upper limb, P < .001; lower limb, P = .019) and similarly better muscle strength (P < .01), 6-meter walk time (P = .024), and 6-meter backward walk time (P = .039). Exercise also improved several aspects of quality of life including general health (P = .022) and reduced fatigue (P = .021) and decreased levels of C-reactive protein (P = .008). There were no adverse events during the testing or exercise intervention program. Conclusion A relatively brief exposure to exercise significantly improved muscle mass, strength, physical function, and balance in hypogonadal men compared with normal care. The exercise regimen was well tolerated and could be recommended for patients undergoing AST as an effective countermeasure to these common treatment-related adverse effects.
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Ohanian, Maro, Hagop M. Kantarjian, Farhad Ravandi, Gautam Borthakur, Guillermo Garcia-Manero, Michael Andreeff, Elias Jabbour, et al. "Safety, Pharmacokinetics, and Efficacy of BP-100-1.01 (Liposomal Grb-2 Antisense Oligonucleotide) in Patients with Refractory or Relapsed Acute Myeloid Leukemia (AML), Philadelphia Chromosome Positive Chronic Myelogenous Leukemia (CML), Acute Lymphoblastic Leukemia (ALL), and Myelodysplastic Syndrome (MDS)." Blood 126, no. 23 (December 3, 2015): 3801. http://dx.doi.org/10.1182/blood.v126.23.3801.3801.

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Abstract Background: Essential to cancer cell signaling, the growth receptor bound protein-2 (Grb-2) is evolutionarily conserved and utilized by oncogenic tyrosine kinases including Bcr-Abl to activate Ras, ERK, and AKT. BP-100-1.01is a neutrally-charged, liposome-incorporated antisense designed to inhibit Grb-2 expression. Aim: To define the safety, maximum tolerated dose (MTD), optimal biologically active dose, pharmacokinetics and anti-leukemia activity of BP-100-1.01 in patients (pts) with hematologic malignancies. Methods: This is a standard 3+3 phase I dose-finding study in pts with relapsed or refractory acute myeloid leukemia (AML), chronic myeloid leukemia in blast phase (CML-BP), acute lymphoblastic leukemia (ALL) and myelodysplastic syndrome (MDS). The starting dose was 5 mg/m2 twice weekly, IV over 2-3 hours for 28 days. Dose escalation proceeded through 5, 10, 20, 40, 60, and 90 mg/m2.Uponcompletion of single agent phase 1, combination of cytarabine 20 mg SubQ BID x 10 days + 60 mg/m2 of BP-100-1.01 was studied (Cohort 1B). Flow cytometric analysis was performed on peripheral blood samples from cohorts 3, 4, 5, 6 and 1B collected at baseline, on day 15 and at end-of-treatment (EOT). Fluorescent-labeled antibodies specific for Grb-2 or phosphorylated Erk (pErk) were utilized to determine Grb-2 protein levels and pErk levels in CD33-expressing cells. Results: A total of33 pts were included (13 in Cohort 1, 6 in Cohort 2, 3 each in Cohorts 3, 4, 5, and 4 in cohort 6). One patient has been treated in cohort 1B. The median age was 64 yrs (range, 32-89) and diagnoses were AML (n=24), CML-BP (n=5) and MDS (n=4). The median number of prior therapies was 4 (range, 1- 8). Of 33 pts, 21 were evaluable and 11 failed completion of a full 28-Day cycle due to disease progression (with no toxicity) and were replaced, per protocol. Only one pt (treated at 5 mg/m2) experienced dose limiting toxicity (DLT), grade 3 mucositis and hand-foot syndrome, while receiving concurrent hydroxyurea for proliferative CML-BP. The patient had a previous history of hydroxyurea-induced mucositis. Being the first patient to receive BP-100-1.01, these toxicities were considered possibly related to BP-100-1.01. The cohort was expanded to a total of 6 pts. No other DLTs have been noted in any pt. Among 21 evaluable pts, 11 experienced at least a 50% reduction in peripheral or bone marrow blasts from baseline. Additionally 2 pts with improvement in leukemia cutis lesions received 1 cycle each. Furthermore, 6 pts demonstrated transient improvement (n=3) and/or stable disease (n=3). Among the 21 evaluable pts, a median of 1 cycle was administered (1-5): Four pts received 2 cycles, 3 pts received 5 cycles, and all others received 1 cycle. Notably one pt (treated at 5 mg/m2)with CML-BP showed a significant reduction in blasts from 81% to 5%. Due to leptomeningeal disease progression therapy was discontinued before a full cycle. The 1st patient treated in cohort 1B achieved CR after 1 cycle. The patient did not experience any DLTs, but came off study due to failure to thrive in the context of dementia. The levels of Grb-2 and pErk proteins were indicated by their respective median fluorescent signals and are shown in the table. Median fluorescent signals of Grb-2 and pErk on days 15 and EOT were compared to baseline. On day 15 Grb-2 levels decreased by >25% in 7 out of 12 samples tested, and pErk levels by >25% in 6 out of 12 samples. The average decrease in Grb-2 levels was 61% (range: 47 to 85%) and in pErk levels 52% (range: 28 to 82%). On the last measured sample (EOT or day 22), BP-100-1.01 decreased >25% Grb-2 levels in 11 out of 13 samples, and >25% pErk levels in 7 out of 13 samples. The average decrease in Grb-2 levels was 49% (range: 28 to 91%) and in pErk levels was 52% (range: 27 to 91%). Table 1. Patient Number Grb-2 decrease (Day 15) pErk decrease (Day 15) Grb-2 decrease (Day 22 or EOT) pErk decrease (Day 22 or EOT) 022 0 0 57 0 023 0 3 28 45 024 56 28 47 35 025 63 82 54 91 026 47 0 0 0 027 NS NS 34 27 028 0 0 30 54 029 57 51 65a 0a 030 54 55 43 47 031 0 0 0 0 032 85 54 91 63 033 6 13 53 2 034 63 42 40 0 NS = no sample collected aFewer cells were used in the analysis of this sample than other samples, because this sample had less cells than other samples Conclusions: BP-100-1.01, at dose range 5 mg/m2 to 90 mg/m2 is well tolerated with no MTD yet identified. There is suggestion of Grb-2 target protein down-regulation, and possible anti-leukemia activity. Disclosures Konopleva: Novartis: Research Funding; AbbVie: Research Funding; Stemline: Research Funding; Calithera: Research Funding; Threshold: Research Funding. Tari:Bopath Holdings: Employment. Cortes:BerGenBio AS: Research Funding; Teva: Research Funding; Novartis: Consultancy, Research Funding; Pfizer: Consultancy, Research Funding; Ariad: Consultancy, Research Funding; BMS: Consultancy, Research Funding; Astellas: Consultancy, Research Funding; Ambit: Consultancy, Research Funding; Arog: Research Funding; Celator: Research Funding; Jenssen: Consultancy.
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Dissertations / Theses on the topic "N-022"

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Diaz, Nuñez Indira Mariaeugenia. "Resolución N° 021-2014-OEFA-TFA-SEP1." Bachelor's thesis, Pontificia Universidad Católica del Perú, 2021. http://hdl.handle.net/20.500.12404/19942.

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El objetivo general del trabajo es identificar los vacíos normativos que identificamos en procedimientos administrativos sancionadores, y como ante dicho contexto, la Administración Pública puede incurrir en vicios que vulneren los derechos a los administrados sujetos a su competencia. Pero, este análisis no solo tiene por objetivo identificar dichas falencias y vacíos normativos, sino también plantear soluciones que permiten contribuir de mejor manera en la actuación de la Administración Pública. Los instrumentos que se ha utilizado en presente trabajo es el marco normativo que aplica al sector ambiental dentro un procedimiento administrativo sancionador, la jurisprudencia que aborda los principios del procedimiento administrativo y la doctrina que aborda temas no solo de principios sino también temas como procedente vinculantes en materia administrativa. En ese sentido, entre las principales conclusiones en que llega en el análisis de un caso surgido entre la Empresa Administradora Chungar y el Organismo de Evaluación y Fiscalización Ambiental, es que, se ha vulnerado claramente los principios que rigen el procedimiento administrativo sancionador, y que, por ende, correspondía a uno de los órganos que se interviene dentro del procedimiento que declare la nulidad de lo actuado, pero al no pasar esto, tiene por resultado emitir un precedente vinculante que contraviene el marco normativo aplicable.
The general objective of the work is to identify the regulatory gaps that we identify in administrative sanctioning procedures, and as in this context, the Public Administration may incur in vices that violate the rights of the administrations subject to its competence. However, this analysis is not only intended to identify these gaps and regulatory gaps, but also to propose solutions that allow a better contribution to the performance of the Public Administration. The instruments that have been used in this work are the normative framework that applies to the environmental sector within an administrative sanctioning procedure, the jurisprudence that addresses the principles of the administrative procedure and the doctrine that addresses issues not only of principles but also issues such as binding in administrative matter. In this sense, among the main conclusions reached in the analysis of a case that arose between the Chungar Administrative Company and the Environmental Assessment and Enforcement Agency, is that the principles that govern the administrative sanctioning procedure have been clearly violated, and that Therefore, it corresponded to one of the bodies that intervenes within the procedure to declare the nullity of the action, but when this does not happen, the result is to issue a binding precedent that contravenes the applicable regulatory framework.
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Torres, Meza Eveling Miyarely. "Informe sobre Expediente N° 02-2009-CLC." Bachelor's thesis, Pontificia Universidad Católica del Perú, 2020. http://hdl.handle.net/20.500.12404/17298.

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El presente trabajo desarrolla el primer pronunciamiento de la Autoridad de la Competencia del Indecopi en el que se reconoce que las actividades sindicales se encuentran exentas del control antitrust. Así, desde el análisis interdisciplinario del Derecho Colectivo de Trabajo y del Derecho de Libre competencia se cuestiona: i) si los sindicatos constituyen agentes económicos, ii) si las actividades sindicales se encuentran exentas de la aplicación del Decreto Legislativo No. 1034 y iii) si en el procedimiento administrativo en concreto se configuraron las prácticas colusorias horizontales imputadas por el órgano administrativo. Del análisis de lo anterior, se concluye, en primer lugar, que los sindicatos no son agentes económicos, en tanto los fines para los cuales fueron constituidos distan de la calificación de agente económico que desarrollan las normas de libre competencia. En segundo lugar, se señala que nuestro ordenamiento jurídico garantiza la vigencia de los derechos sindicales y, en este sentido, resulta necesario el reconocimiento de una exención en favor de las actividades sindicales respecto del control antitrust. Finalmente, se refiere que tal exención no supone que se admita el abuso de derecho por parte de los sindicatos o el ejercicio irregular de sus derechos sindicales (situaciones que deberán ser analizadas por las autoridades laborales correspondientes) y que- de advertirse que los sindicatos se comporten en la práctica como agentes económicos en sí mismos, estos sí puedan ser considerados pasibles de sanción por las normas que rigen la libre competencia.
Trabajo de suficiencia profesional
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Barboza, Patrícia de Mello. "Pregão: procedimento à luz da Lei n. 10.520/02." Pontifícia Universidade Católica de São Paulo, 2011. https://tede2.pucsp.br/handle/handle/5537.

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This thesis analyzes the bidding method, introduced in the legal system by Law No. 10.520/02, with regard specifically to a differential procedure addressing, first, to the characteristics that draw its lines and then examine each of the phases that compose it, by giving prominence to certain aspects that are deemed most relevant
Esta dissertação analisa o pregão, modalidade de licitação introduzida no ordenamento jurídico pela Lei n. 10.520/02, no que diz respeito especificamente ao seu rito diferenciado, abordando, primeiro, as características que lhe traçam o figurino, para depois examinar cada qual das fases que o compõem, dando-se destaque a certos aspectos que se julgou de maior relevância, a exemplo do momento do recebimento e da análise de amostra
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Canado, Vanessa Rahal. "As regras-matrizes de incidência tributária da Contribuição para o Financiamento da Seguridade Social (COFINS) nos regimes "cumulativo", "não-cumulativo", de "incidência monofásica" e de "substituição tributária", previstos na Lei Complementar n. 70/91 e nas leis n. 9.718/98, n. 10.147/00, n. 10.485/02, n. 10.560/02 e n. 10.833/03." Pontifícia Universidade Católica de São Paulo, 2008. https://tede2.pucsp.br/handle/handle/8022.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
The main objective of this dissertation is to construct the essential rules connected to the levy ( regras matrizes de incidência tributária ) of the COFINS tax, based on provisions contained under specific laws which govern the four main collection regimes of said contribution: cumulative , noncumulative , single-phase taxation and tax substitution . Based on the provisions of Complementary Law n. 70/91 and of Law n. 9.718/98, we have constructed, besides the generic rule of levy of the COFINS in the cumulative regime , other 6 (six) specific rules, referred to herein as differentiated treatments in the cumulative regime . Essentially, from the provisions under Law n. 10.833/03, besides the generic rule of levy of the COFINS in the non-cumulative regime , we identified 12 (twelve) more specific rules of levy, also referred to as "differentiated treatments in the non-cumulative regime." In turn, with regard to the tax substitution COFINS regime, solely the manufacturers and wholesale sellers of cigarettes remained, according to the provisions under Article 3 of Complementary Law n. 70/91 and Article 29 of Law n. 10.865/04. Finally, based on the provisions of Laws n. 9.718/98 (Articles 4, 5 and 6), n. 10.147/00, n. 10.485/02, n. 10.560/02 and n. 10.833/03 (Article 49), we could identify 12 (twelve) rules of the levy of the COFINS in the so-called single-phase taxation regime. Besides the aforementioned legislation, specific provisions under Provisional Measure n. 2.158-35/01 and Laws n. 10.684/03, n. 10.865/04, n. 10.925/04, n. 11.051/04 and 11.196/05 were also necessary for the analysis and description of the rules of levy of the COFINS which were constructed herein
Esta dissertação tem como principal objetivo construir as normas tributárias de incidência (regras-matrizes de incidência tributária) da COFINS, a partir de enunciados prescritivos contidos em leis específicas que regem os quatro principais regimes de apuração da referida contribuição: cumulativo , não-cumulativo , de incidência monofásica e de substituição tributária . Tomando-se por base os enunciados da Lei Complementar n. 70/91 e da Lei n. 9.718/98, foi possível construirmos, além da regra-matriz de incidência tributária genérica , para apuração da COFINS no regime cumulativo , outras 6 (seis) regras específicas, que denominamos de tratamentos diferenciados no regime cumulativo . A partir, essencialmente, dos enunciados da Lei n. 10.833/03, além da regra de incidência genérica da COFINS no regime não-cumulativo , pudemos construir mais 12 (doze) normas específicas de incidência, que denominamos, também, de tratamentos diferenciados no regime nãocumulativo . No regime de substituição tributária , restaram apenas os fabricantes e comerciantes atacadistas de cigarros, conforme disposições do artigo 3º, da Lei Complementar n. 70/91 e do artigo 29, da Lei n. 10.865/04. Por fim, descrevendo acerca dos enunciados das Leis n. 9.718/98 (artigos 4º, 5º e 6º), n. 10.147/00, n. 10.485/02, n. 10.560/02 e n. 10.833/03 (artigo 49), pudemos construir 12 (doze) regras-matrizes de incidência tributária da COFINS no regime denominado de incidência monofásica . Além das leis acima citadas, também prescrições específicas da Medida Provisória n. 2.158-35/01 e das Leis n. 10.684/03, n. 10.865/04, n. 10.925/04, n. 11.051/04 e n. 11.196/05 foram necessárias para a delimitação das normas construídas
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Hernandez, Eduardo Arturo Vantini [UNESP]. "Inovações do Código de Processo Civil e seus reflexos no Direito Processual do Trabalho: uma análise crítica das leis n.10352/01, n.10358/01, n.10444/02, n.11187/05, 11232/05, n.11276/06, n.11277/06, n.11280/06 e n.11382/06." Universidade Estadual Paulista (UNESP), 2007. http://hdl.handle.net/11449/89879.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
O Direito é uma ciência em constante evolução e adaptação aos anseios sociais em determinado local em certo momento histórico, por isso podemos dizer que estamos falando de uma ciência em construção. Nesse sentido, o Direito não se encontra pronto e acabado, especialmente em países de tradição legiferante como o Brasil, mas se faz renovado a cada dia, com a implementação de novas normas nos mais variados assuntos. No presente trabalho veremos um estudo das recentes alterações legislativas ocorridas no Direito Processual Civil e seus principais reflexos no Direito Processual do Trabalho, através da análise crítica das Leis n.º 10.352/01, n.º 10.358/01, n.º 10.444/02, n.º 11.187/05, n.º 11.232/05, n.º 11.276/06, n.º 11.277/06, n.º 11.280/06 e n.º 11.382/06. No primeiro capítulo, deste estudo, tem-se uma abordagem sobre os princípios e fontes do direito do trabalho como premissas hermenêuticas a nortear e fundamentar os demais capítulos da pesquisa. Na seqüência, encontra-se um capítulo que trata do ordenamento jurídico de maneira genérica, sua autonomia, a noção de sistema e a relação existente entre as disciplinas estudadas; de forma especifica verifica-se a abordagem de questões hermenêuticas, para fundamentação e aplicação das normas do processo civil ao processo do trabalho. Superados as questões propedêuticas dos primeiros capítulos, passa-se a explorar especificamente as alterações efetuadas no Direito Processual Civil, procurando de forma prática e conclusiva demonstrar sua co-relação e eventual utilização no Direito Processual do Trabalho. O estudo nesse capítulo é complementado com referências jurisprudenciais a fim de confrontar o entendimento empossado com a tendência do judiciário ao decidir o caso concreto. O desenvolvimento da presente pesquisa, não procura atender a um único objetivo, mas de maneira geral...
The Law is a science in a constant evolution and adaptation to the social cravings in a certain place and in a certain historic moment, because of that we can say we are talking about a science under construction. With that meaning, the Law is not ready and done, especially in countries of legislative tradition like Brazil, but it is renewed at every single day with implementation of new norms about the most varied subjects. This paper shows a study of the recent legislative alterations occurred in the Civil Procedural Law and its main reflexes in the Work Procedure Law through the critical analysis of the Laws nº 10.352/01, nº 10.358/01, nº 10.444/02, nº 11.187/05, nº 11.232/05, nº 11.276/06, nº 11.277/06, nº 11.280/06 and nº 11.382/06. In the study performed in the first chapter, there is an approach about the principles and sources of the labor law as hermeneutic premises to lead and ground the other chapters of the research. In the sequence, there is a chapter about the legal system in a generic way, its autonomy, the notion of system and the relation found in the studied disciplines; in a specific way, an approach of hermeneutic matters is checked to foundation and implementation of the norms of the civil procedure to the labor procedure. Solved the propaedeutic matters of the first chapters, an exploration, specifically in the alterations performed in the Civil Procedural Law, starts to be done; trying to show, in a practical and conclusive way, its correlation and possible use in the Work Procedural Law. The study in this chapter is concluded with jurisprudential references in order to confront the understanding installed with the tendency of the judiciary when deciding the concrete case. The development of the present research does not try to serve an only objective, but in a general way, to show the complexity and the incompleteness of the legal system, in a way... (Complete abstract, click electronic access below)
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Hernandez, Eduardo Arturo Vantini. "Inovações do Código de Processo Civil e seus reflexos no Direito Processual do Trabalho : uma análise crítica das leis n.10352/01, n.10358/01, n.10444/02, n.11187/05, 11232/05, n.11276/06, n.11277/06, n.11280/06 e n.11382/06 /." Franca : [s.n.], 2007. http://hdl.handle.net/11449/89879.

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Orientador: Enoque Ribeiro dos Santos
Banca: Ronaldo Lima dos Santos
Banca: Elisabete Maniglia
Resumo: O Direito é uma ciência em constante evolução e adaptação aos anseios sociais em determinado local em certo momento histórico, por isso podemos dizer que estamos falando de uma ciência em construção. Nesse sentido, o Direito não se encontra pronto e acabado, especialmente em países de tradição legiferante como o Brasil, mas se faz renovado a cada dia, com a implementação de novas normas nos mais variados assuntos. No presente trabalho veremos um estudo das recentes alterações legislativas ocorridas no Direito Processual Civil e seus principais reflexos no Direito Processual do Trabalho, através da análise crítica das Leis n.º 10.352/01, n.º 10.358/01, n.º 10.444/02, n.º 11.187/05, n.º 11.232/05, n.º 11.276/06, n.º 11.277/06, n.º 11.280/06 e n.º 11.382/06. No primeiro capítulo, deste estudo, tem-se uma abordagem sobre os princípios e fontes do direito do trabalho como premissas hermenêuticas a nortear e fundamentar os demais capítulos da pesquisa. Na seqüência, encontra-se um capítulo que trata do ordenamento jurídico de maneira genérica, sua autonomia, a noção de sistema e a relação existente entre as disciplinas estudadas; de forma especifica verifica-se a abordagem de questões hermenêuticas, para fundamentação e aplicação das normas do processo civil ao processo do trabalho. Superados as questões propedêuticas dos primeiros capítulos, passa-se a explorar especificamente as alterações efetuadas no Direito Processual Civil, procurando de forma prática e conclusiva demonstrar sua co-relação e eventual utilização no Direito Processual do Trabalho. O estudo nesse capítulo é complementado com referências jurisprudenciais a fim de confrontar o entendimento empossado com a tendência do judiciário ao decidir o caso concreto. O desenvolvimento da presente pesquisa, não procura atender a um único objetivo, mas de maneira geral... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: The Law is a science in a constant evolution and adaptation to the social cravings in a certain place and in a certain historic moment, because of that we can say we are talking about a science under construction. With that meaning, the Law is not ready and done, especially in countries of legislative tradition like Brazil, but it is renewed at every single day with implementation of new norms about the most varied subjects. This paper shows a study of the recent legislative alterations occurred in the Civil Procedural Law and its main reflexes in the Work Procedure Law through the critical analysis of the Laws nº 10.352/01, nº 10.358/01, nº 10.444/02, nº 11.187/05, nº 11.232/05, nº 11.276/06, nº 11.277/06, nº 11.280/06 and nº 11.382/06. In the study performed in the first chapter, there is an approach about the principles and sources of the labor law as hermeneutic premises to lead and ground the other chapters of the research. In the sequence, there is a chapter about the legal system in a generic way, its autonomy, the notion of system and the relation found in the studied disciplines; in a specific way, an approach of hermeneutic matters is checked to foundation and implementation of the norms of the civil procedure to the labor procedure. Solved the propaedeutic matters of the first chapters, an exploration, specifically in the alterations performed in the Civil Procedural Law, starts to be done; trying to show, in a practical and conclusive way, its correlation and possible use in the Work Procedural Law. The study in this chapter is concluded with jurisprudential references in order to confront the understanding installed with the tendency of the judiciary when deciding the concrete case. The development of the present research does not try to serve an only objective, but in a general way, to show the complexity and the incompleteness of the legal system, in a way... (Complete abstract, click electronic access below)
Mestre
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7

Alcalá, Quevedo Angelina Andrea. "Informe para la sustentación de expedientes: N° 00881-2008-0-1801-JR-FC-02 / N° 131-2015/CPC-INDECOPI-PIU." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2021. http://hdl.handle.net/10757/656441.

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El expediente privado seleccionado para optar por el título profesional de Abogado, corresponde a una demanda de divorcio por causal de separación de hecho interpuesta ante el Segundo Juzgado de Familia de Lima y que posteriormente fue elevado hasta la Sala Civil Permanente de la Corte Suprema de Justicia de la República. La relevancia del expediente privado escogido radica en verificar si se ha cumplido con los elementos de la causal invocada, en especial el referente al tiempo de separación (elemento temporal) o si de lo contrario el plazo se ha interrumpido; ya que es este elemento el que jugará un papel relevante en el sentido de la posición de los jueces en las distintas instancias del proceso. Asimismo, de acreditarse que se ha cumplido con el elemento temporal, es necesario determinar si conforme a la reconvención formulada por la demandada, corresponde declarársele como cónyuge perjudicada y por ende indemnizarla; razón por la cual se tendrán que analizar los criterios establecidos en el Tercer Pleno Casatorio Civil.
Trabajo de suficiencia profesional
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Torres, Castillo Alfredo Junior. "Informe sobre Expediente N° 003-2013-PI/TC, Nº 004-2013-PI/TC y Nº 023-2013-PI/TC." Bachelor's thesis, Pontificia Universidad Católica del Perú, 2020. http://hdl.handle.net/20.500.12404/17865.

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El expediente jurídico versa sobre un tema actual, complejo y muy desafiante, cuya investigación permitirá una visión panorámica y realista del derecho laboral peruano respecto al sector público. De esta manera, la hipótesis del presente informe radica en que los trabajadores públicos tienen el derecho a la negociación colectiva en materia económica, basados en un análisis de los principales instrumentos relacionados a los derechos fundamentales de la persona. La conclusión del presente informe evidenció a raíz de una interpretación sistemática de los cuerpos jurídicos nacionales e internacionales (entre ellos, los Tratados Internacionales de Derechos Humanos, Convenios de la Organización Internacional de Trabajo, Comité Libertad Sindical, Comisión de Expertos para la Aplicación de Convenios y Recomendaciones), que se debe regular a nivel legal la negociación colectiva en el sector público a través de un diálogo social que procure el respeto de otros principios constitucionales como el presupuestario.
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Salvato, M. "Performance of wetland systems in reducing agricultural nitrogen pollution." Doctoral thesis, Università degli studi di Padova, 2010. http://hdl.handle.net/11577/3426572.

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The thesis is about the performance of wetland systems in reducing agricultural nitrogen pollution. It takes into account two experiments at different scale: a 3200 m2 pilot surface wetland and a mesocosm trial. In the first case the aim was to evaluate the performance of the wetland, located at the experimental farm of the University of Padova (Italy), in abating nitrogen coming from 5 ha of surrounding fields. Overall, for the entire period (2.5 years), the basin performed well in abating both nitrate and total nitrogen with a removal efficiency of about 90%. The major quantity of removed nitrogen was stored in vegetation and soil and only 6% was estimated as being lost with denitrification. In the mesocosm experiment the aim was to compare five different species in abating nitrogen coming from a reconstructed wastewater. The experimental setup consisted of plastic tanks, filled with gravel and vegetated with Carex elata All., Juncus effusus L., Typhoides arundinacea (L.) Moench var. picta, Phragmites australis (Cav.) Trin. and Typha latifolia L.. There was also a control without vegetation. A solution of increasing concentrations of NH4-N and NO3-N was applied to the tanks, over 31 cycles of differing lengths. At the end of each cycle exiting water was analysed to determine the two nitrogen forms. All water volumes entering and exiting the tanks were measured in order to evaluate evapotranspiration. At the end of the trials T. latifolia had removed 82% of the entering nitrogen, followed by T. arundinacea (76%), C. elata (75%), Ph. australis (72%) and J. effusus (64%). The control removed 45% of the entering nitrogen. The fate of the two forms of nitrogen differed as NH4-N disappeared almost completely and in short time in all the treatments while NO3-N showed different removal efficiency depending on season and considered species. The major quantity of entering nitrogen was stored in plant tissues with different percentages depending on species. The calculated denitrification varied from 18% for J. effusus to 37% for T. arundinacea.
Il lavoro è consistito nello studio dell’efficienza delle zone umide costruite nel ridurre l’azoto proveniente dall’inquinamento di origine agricola. La tesi prende in considerazione due prove sperimentali a diversa scala nel triennio 2007-2009: una zona umida a flusso superficiale di 3200 m2 e una prova a scala di mesocosmo. Nel primo caso l’obiettivo era di valutare l’efficienza della zona umida sita presso l’azienda agraria sperimentale dell’Università degli Studi di Padova, nell’abbattere azoto proveniente da 5 ha di circostante terreno coltivato. Alla fine del periodo considerato (2.5 anni) il bacino ha dimostrato di abbattere molto bene sia l’azoto nitrico che totale con efficienze di rimozione introno al 90%. La maggior parte dell’azoto in entrata è stata immagazzinata nel comprato suolo/vegetazione mentre la denitrificazione è stata stimata pari al 6%. Nella prova a scala di mesocosmo l’obiettivo era di comparare l’efficienza di rimozione dell’azoto di cinque diverse specie. L’impianto sperimentale era costituito da vasche in plastica riempite di ghiaia e vegetate con Carex elata All., Juncus effusus L., Typhoides arundinacea (L.) Moench var. picta, Phragmites australis (Cav.) Trin., and Typha latifolia L.. Era presente anche un controllo non vegetato. Una soluzione con concentrazioni crescenti di NH4-N and NO3-N è stata applicata alle vasche effettuando 31 cicli di diversa durata. Alla fine di ogni ciclo l’acqua in uscita dalle vasche è stata analizzata per azoto nitrico e ammoniacale. I volumi di acqua in entrata e uscita sono stati misurati al fine di calcolare l’evapotraspirazione. Considerando tutti e tre gli anni di prova, Typha latifolia L. ha rimosso l’82% dell’azoto in entrata seguita da Typhoides arundinacea (L.) Moench (76%), var. picta, Carex elata All. (75%), Phragmites australis (Cav.) Trin., (72%) e Juncus effusus L. (64%). Il controllo non vegetato ha rimosso invece il 45%. Azoto ammoniacale e nitrico hanno presentato diverse dinamiche di scomparsa. Il primo è stato abbattuto quasi completamente e in breve tempo in tutti i trattamenti, il secondo invece è stato rimosso in maniera diversa a seconda della stagione e della specie considerata. La maggior quantità di azoto in entrata è stata immagazzinata nei tessuti con percentuali diverse secondo le specie. La denitrificazione calcolata varia dal 18% in Juncus effusus L. al 37% in Typhoides arundinacea (L.) Moench var.picta.
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Corrêa, Inésio Antônio Marinho. "Efeito do distanciamento da BR-020 na produtividade primária líquida, concentração de N e S na serapilheira foliar e eficiência no uso de N e S de uma comunidade vegetal da Estação Ecológica de Águas Emendadas." reponame:Repositório Institucional da UnB, 2017. http://repositorio.unb.br/handle/10482/24606.

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Dissertação (mestrado)—Universidade de Brasília, Faculdade UnB Planaltina, Programa de Pós-Graduação em Meio Ambiente e Desenvolvimento Rural, 2017.
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As emissões de dióxido de enxofre (SO2) e dióxido de nitrogênio (NO2) provenientes da queima de combustíveis fósseis podem estar contribuindo para a alteração do metabolismo das comunidades vegetais, influenciando na ciclagem de nutrientes em ecossistemas terrestres e aquáticos. Como várias unidades de conservação, a Estação Ecológica Águas Emendadas (ESECAE) tem seu perímetro poligonal conectado a rodovias e significativa expansão urbana. Considerando que sulfato e nitrato podem ser absorvidos via estômatos, as comunidades vegetais , principalmente, as localizados na borda, estão expostas, a efeitos resultantes da emissão de gases de veículos automotores. Sendo assim, o objetivo da presente pesquisa foi verificar o efeito da distância da rodovia federal BR-020 na produtividade primária líquida, concentração de N e S na serapilheira foliar e eficiência no uso de N e S em uma comunidade vegetal localizada na parte sul da ESECAE. O delineamento experimental foi instalado em uma área de seis ha e foi composto de seis tratamentos (60, 80, 110, 170, 290 e 350 m de distância da rodovia), onde foram instalados coletores de serapilheira (0,25 m2 a 50 cm do solo), com cinco repetições por tratamento. A serapilheira foi coletada mensalmente e, bimensalmente, a fração folha foi submetida à análise para determinação da concentração de N e S. Considerando os valores mensais, foi possível identificar efeito da distância da rodovia somente nos padrões de concentração e eficiência no uso de S. Observamos que ocorreu maior constância nos valores destes parâmetros com maior concentração da S na serapilheira e menores valores até 60 em relação às faixas mais internas. Considerando os valores anuais, houve diminuição na EUS e maior concentração e fluxo de S na serapilheira foliar até 60m em relação às distâncias mais internas da comunidade (80-350). Não se observou diferenças significativas na produção primária líquida, na concentração e eficiência no uso de N. Concluímos que o efeito do distanciamento da rodovia BR-020 ocorre até 60m e só é significativo quando as variáveis PPL e concentração de S são analisadas conjuntamente. Assim, mudança nos padrões de ciclagem de S em comunidades vegetais em contato com rodovias deve ser considerada na criação e elaboração de planos de manejo das unidades de conservação nacionais e internacionais.
Sulfur dioxide (SO2) and nitrogen dioxide (NO2) emissions derived from fossil fuels’ burning may be altering plant communities’ metabolism and as well as the terrestrial and the aquatic ecosystems’ nutrient cycling. The Estação Ecológica de Águas Emendadas (ESECAE), like many conservation units, has its perimeter connected to highways and urban expansion areas. Considering that stomata can absorb sulfate and nitrate, plant communities, mainly those located nearby the boarders, are exposed to the effects of motor vehicle gas emissions. Therefore, the purpose of this research was to evaluate the distance from the BR-020 federal highway on the primary net productivity, the leaf litter N and S concentrations and the N and S usage efficiency on the South part of the ESECAE reserve. The experimental design was placed in a six-hectare area, composed by six treatments (60, 80, 110, 170, 290 and 350 m away from the highway), using litter collectors (0,25 m2 litter collector at 50 cm above ground), with 5 replicates per treatment. Litter was collected monthly and every other month, the N and S concentrations from the litter leaf fractions were measured. Considering the monthly values, we only identified the effect of the distance on the S concentration patterns and its usage efficiency. We noticed a higher uniformity on these parameter’s values with higher S concentration on the litter and lower values until 60 m in comparison to the internal bands. Considering the annual values, the EUS reduced and the S flux and concentrations were higher on the foliar litter until 60 m when compared to the innermost community distances (80-350). We didn’t notice any significant differences on the primary net production nor on the N concentration and its usage efficiency. We concluded that the distance from the BR-020 highway effect occurred up to 60 m and was only significant when the PPL and S concentrations were analyzed together. Thus, S cycling pattern changes in plant communities nearby highways must be taken into consideration on the management planning of national and international conservation units.
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Books on the topic "N-022"

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Janowska, Maria. Opis bibliograficzny wydawnictw ciągłych: Interpretacja postanowień PN-N-01152-02. Warszawa: Biblioteka Narodowa, 1996.

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United States. Bureau of Labor Statistics., ed. Employee Benefits In Small Private Establishments, 1996, Bulletin 2507, April 1999, S/N 029-001-03319-2. [S.l: s.n., 1999.

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Egidio, Albanese, ed. La responsabilità del medico per colpa professionale alla luce della sentenza n. 30328/02 delle S.U. della cassazione. Bari: Adriatica, 2003.

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Kleeschulte, Michael J. Stratigraphy and vertical hydraulic conductivity of the St. Francois confining unit in townships 25-27 N. and ranges 01-02 W., southeastern Missouri. Rolla, Mo. (1400 Independence Rd., Mail stop 100, Rolla 65401): U.S. Dept. of the Interior, U.S. Geological Survey, 2001.

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1954-, Meyer Lidwina, ed. Wie kann Gestern morgen besser werden?: Jüdisch-christlich-muslimische Geschichte(n) ; 4. Interreligiöse Sommeruniversität ; [Dokumentation einer Tagung der Evangelischen Akademie Loccum vom 02. bis 09. Juli 2003]. Rehburg-Loccum: Evangelische Akademie Loccum, Protokollstelle, 2005.

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Clark, Mary Higgins. I'll walk alone. Waterville, Me: Thorndike Press, 2011.

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Clark, Mary Higgins. I'll walk alone. New York: Pocket Books, 2012.

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Clark, Mary Higgins. Quand reviendras-tu? [Paris]: Albin Michel, 2011.

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Federal Interagency Forum on Aging-Related Statistics. Older Americans 2000: Key Indicators of Well-Being (S/N 017-022-01504-8). US Government Printing Office, 2001.

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Health, United States, 1998 : Socioeconomic Status and Health Chartbook (s/n 017-022-01422-0). U.S. Government Printing Office, 1998.

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Book chapters on the topic "N-022"

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Halstrøm, J., and K. Kovcás. "IMPROVED PREPARATION OF CRYSTALLINE N-(9-XANTHYL) AMINO ACID N-CARBOXYANHYDRIDES FOR PEPTIDE SYNTHESIS." In Porto Carras, Chalkidiki, Greece, Aug. 31–Sept. 5, 1986, edited by Dimitrios Theodoropoulos, 111–14. Berlin, Boston: De Gruyter, 1987. http://dx.doi.org/10.1515/9783110864243-022.

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Azadi, Parastoo, and Christian Heiss. "Mass Spectrometry of N-Linked Glycans." In Glycomics, 37–51. Totowa, NJ: Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-022-5_3.

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Kawasaki, Nana, Satsuki Itoh, and Teruhide Yamaguchi. "LC/MS n for Glycoprotein Analysis: N-Linked Glycosylation Analysis and Peptide Sequencing of Glycopeptides." In Glycomics, 239–48. Totowa, NJ: Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-022-5_18.

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Ng, L. K., and J. R. Dillon. "The utility of serological, biological and molecular typing schemes to differentiate N. gonorrhoeae isolates requiring proline, citrulline and uracil (PCU) for growth." In Neisseriae 1990, edited by Mark Achtman, Peter Kohl, Christian Marchal, Giovanna Morelli, Andrea Seiler, and Burghard Thiesen, 111–16. Berlin, Boston: De Gruyter, 1991. http://dx.doi.org/10.1515/9783110867787-022.

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Adachi, Seiji, Patrick Laffez, H. Yamauchi, Shoji Tanaka, and Nobuo Môri. "(Sr,Ca)-Cu-O Superconductors of “02(n-1)n” Structure." In Advances in Superconductivity VI, 297–300. Tokyo: Springer Japan, 1994. http://dx.doi.org/10.1007/978-4-431-68266-0_62.

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Morelle, Willy, Valegh Faid, Frédéric Chirat, and Jean-Claude Michalski. "Analysis of N- and O-Linked Glycans from Glycoproteins Using MALDI-TOF Mass Spectrometry." In Glycomics, 3–21. Totowa, NJ: Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-022-5_1.

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Wood, Michael. "Ein Dialog mit einigen Toten." In Heiner Müllers KüstenLANDSCHAFTEN, 403–20. Bielefeld, Germany: transcript Verlag, 2021. http://dx.doi.org/10.14361/9783839455630-022.

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In diesem Aufsatz untersucht Michael Wood einen scheinbaren Widerspruch im Werk und Denken Müllers, indem er den Zusammenhang zwischen offenem Dialog und literarischen Tradition dabei näher hinsieht. Für Müller bildet der »Dialog mit den Toten« eine zentrale Stütze sowohl in seiner literarischen und dramaturgischen Praxis als auch im »universale[n] Diskurs, der nichts ausläßt und niemanden ausschließt«. Als Teil dieses Dialogs nimmt das Werk Müllers viele Bezüge auf die Ideen und Werke diverser anderen Dichter und Denker aus mannigfaltigen literarischen und intellektuellen Traditionen. Müllers Wahl ist aber selektiv. Hier erörtere ich Müllers Weiberkomödie (1969), die dank ihrer Abweichungen von unseren Erwartungen von den Werken Heiner Müllers selten besprochen wird. Anhand einer Analyse dieses Stücks neben Bürgermeister Anna von Friedrich Wolf (1950) behaupte ich, dass Weiberkomödie eine Ausgrenzung Wolfs und seiner Nachkommen aus einer Geschichte der zukunftsgestaltenden Literatur inszeniert.
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Lewandrowski, Urs, and Albert Sickmann. "N-Glycosylation Site Analysis of Human Platelet Proteins by Hydrazide Affinity Capturing and LC-MS/MS." In Glycomics, 225–38. Totowa, NJ: Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-022-5_17.

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Gong, Bing, Michael Cukan, Richard Fisher, Huijuan Li, Terrance A. Stadheim, and Tillman Gerngross. "Characterization of N-Linked Glycosylation on Recombinant Glycoproteins Produced in Pichia pastoris Using ESI-MS and MALDI-TOF." In Glycomics, 213–23. Totowa, NJ: Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-022-5_16.

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Guelachvili, G., and N. Picqué. "Table 27. D2 16O (D16OD): Spectroscopic parameters for the (400), (301), (202), (221), (122), and (023) interacting vibrational states belonging to the n = 4 polyad." In Non-linear Triatomic Molecules, 132–33. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-41449-7_29.

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Conference papers on the topic "N-022"

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King, Shelby, Sterling Hubbard, and Jenni Teeters. "An Interactive Personalized Feedback and Text-Messaging Intervention is Associated with Reductions in Substance-Impaired Driving." In 2020 Virtual Scientific Meeting of the Research Society on Marijuana. Research Society on Marijuana, 2021. http://dx.doi.org/10.26828/cannabis.2021.01.000.38.

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Background: Substance-impaired driving continues to be a national public health concern and data suggests that up to one-third of college students report driving after drinking and/or cannabis use in the past year. To date, little research has investigated whether brief, technology-based interventions can be used to reduce substance-impaired driving among young adults. Recent research indicates that interventions that incorporate personal contact lead to larger effect sizes than fully automated interventions. The present study compared an interactive text-messaging intervention to an automated text-messaging intervention in the context of a brief, mobile-phone based substance-impaired driving intervention. Method: Participants were recruited through the university’s subject pool (n = 46) and completed measures that assessed impaired driving at baseline and three-month follow-up. In order to be eligible, students had to be at least 18 years or older, have access to a motor vehicle, and report driving after drinking two or more drinks and/or driving after cannabis use at least three times in the past three months. Participants were randomly assigned into four conditions: personalized feedback plus text-messaging (n = 12), personalized feedback plus automated text messaging (n = 11), an active control condition- (substance use information, n = 12), and an assessment only control condition (n = 11). Results: Repeated measures ANOVAs were run to compare the number of times driving while impaired over time across conditions. Analyses revealed the personalized feedback plus text-messaging led to significantly greater reductions over time in the number of times driving while impaired compared to participants in the assessment-only condition (p = .022). Additionally, participants in the personalized feedback plus text-messaging condition reported a greater reduction over time in the number of times driving while impaired than those in the personalized feedback plus automated text messaging condition, though this difference was not significantly significant (p = .066). Surprisingly, the text-messaging conditions did not result in significantly greater reductions in substance-impaired driving compared to the active control condition (p = .227). Discussion: Overall, these findings provide preliminary support for the short-term efficacy of a mobile-delivered personalized feedback intervention with interactive text-messaging in reducing substance-impaired driving among young adults. Due to Covid-19, three-month follow-up data could not be collected from half of the originally enrolled sample, resulting in underpowered analyses. Additional data will be collected as part of this pilot trial in the coming year.
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Sadeghi, Ayla, Kyra Farrelly, and Jeffrey Wardell. "Motives and Consequences Associated with Solitary Alcohol and Cannabis Use among Co-Users during the COVID-19 Pandemic." In 2022 Annual Scientific Meeting of the Research Society on Marijuana. Research Society on Marijuana, 2022. http://dx.doi.org/10.26828/cannabis.2022.02.000.07.

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Background: The COVID-19 pandemic resulted in lockdowns that had an impact on alcohol and cannabis use behavior. During the height of the early lockdowns, many individuals shifted to using alcohol and cannabis in solitary contexts (e.g., Wardell et al., 2020). Solitary drinking is a non-normative behaviour that can predict severe alcohol problems and is associated with coping-motivated drinking (Keough et al. 2018; Skrzynski & Creswell, 2020). Similarly, solitary cannabis use is associated with cannabis use disorder and using cannabis to cope (Spinella et al., 2019). Further, co-use of alcohol and cannabis is related to negative consequences such as alcohol use disorder, depressive symptoms, and impaired driving (Yurasek et al., 2017). As there has been limited research on solitary alcohol and cannabis co-use, this study examined substance use motives and consequences associated with solitary use of both alcohol and cannabis among co-users during the pandemic. Methods: Canadians (N=149; 46% female; mean age = 31 years old) who reported co-use of alcohol and cannabis completed an online survey approximately 6-8 weeks into the first COVID-19 lockdown. Participants reported on past 30-day alcohol and cannabis use, solitary use, motives, and problems (i.e., Short Inventory of Problems and Marijuana Problems Scale). Participants were divided into two groups: those reporting predominantly solitary use of both alcohol and cannabis during the lockdown (solitary co-users; n=61) and those reporting predominantly social use of one or both substances during the lockdown (social co-users; n=88). Logistic regression was used to examine the unique associations of drinking motives and cannabis motives with co-use group (solitary vs. social), and to examine if the solitary co-use group was more likely to report alcohol and cannabis problems (controlling for alcohol and cannabis use). Results: Coping motives for drinking were associated with greater likelihood of being in the solitary vs. social co-use group after controlling for other drinking motives and alcohol use (OR=2.02, p=.023). Conversely, none of the cannabis use motives were significantly associated with membership in the solitary vs. social co-use group. Additionally, compared to social co-users, solitary co-users had higher odds of reporting alcohol problems, including one or more physical problems (OR=2.37, p=.033), intrapersonal problems (OR=3.95, p=.002), and social problems (OR=2.79, p=.022), after controlling for alcohol use. Cannabis-related problems did not differ between solitary and social co-users. Conclusions: Findings provide insight into the motives and consequences of solitary alcohol and cannabis use among co-users during the early stages of the COVID-19 pandemic. These findings suggest that interventions should target co-users who are using both alcohol and cannabis in a solitary context during the pandemic as they appear to be at higher risk for alcohol-related problems. Future research should examine the long-term outcomes of solitary co-use throughout the COVID-19 pandemic. Given that it is not known if the solitary co-users in this study were engaging in simultaneous use of cannabis and alcohol (i.e., using both substances on the same occasion), future ecological momentary assessment (EMA) studies should focus on understanding solitary simultaneous use during the pandemic.
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Čekse, Ireta, and Reinis Alksnis. "Is there a Relationship Between School Factors and Students’ Citizenship Education? The Cases of Latvia and Finland Based on IEA ICCS 2016 Data." In 79th International Scientific Conference of University of Latvia. University of Latvia, 2021. http://dx.doi.org/10.22364/htqe.2021.18.

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In this research, the aim was to determine teacher- and school-level factors that are associated with students’ civic knowledge, future engagement in society as a citizen, opinions about future global issues and sense of belonging to their country. For that purpose, the research took IEA International Civic and Citizenship Education Study (ICCS 2016) questionnaire data from Latvian and Finnish students (Latvia n = 3224, Finland n = 3173), teachers (Latvia n = 1933, Finland n = 2097) and schools (Latvia n = 137, Finland n = 174). The study used a subset of the teacher dataset that corresponds only to those teachers who teach civic and citizenship education lessons in school (Latvia n = 131, Finland n = 165). The research shows that there are some significant relationships with teacher- and school-level factors and four student factors: civic knowledge, future engagement, sense of belonging to their country and global problems (sustainability, violence and economy). The research supported by research application no. 1.1.1.2/VIAA/1/16/020.
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Grévy, S., F. Rotaru, F. Negoita, C. Borcea, R. Borcea, A. Buta, S. Calinescu, et al. "Shape coexistence at N=20 and N=28: Study of 02+ states in 34Si and 44S." In FRONTIERS IN GAMMA-RAY SPECTROSCOPY 2012 - FIG12. AIP Publishing LLC, 2014. http://dx.doi.org/10.1063/1.4893271.

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Aguiar, Caio Henrique Gomes de. "TERRITÓRIO COMO PALCO CULTURAL: ESTUDO DA APROPRIAÇÃO CULTURAL DA COMUNIDADE REMANESCENTE QUILOMBOLA PARATIBE EM JOÃO PESSOA – PB." In Fórum Nacional de Publicações Acadêmicas-Anais-Vol. 03, n. 02, 2024. Home Editora, 2024. http://dx.doi.org/10.46898/home.eb149d7a-9794-431d-83f3-251cc8c2b13c.

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Alves, Luis Carlos. "UMA ANÁLISE SOBRE O COMBATE AO CRIME NO AMBIENTE RURAL PELA POLICIA MILITAR DO PARANÁ: CONSIDERAÇÕES E APERFEIÇOAMENTO." In Fórum Nacional de Publicações Acadêmicas-Anais-Vol. 03, n. 02, 2024. Home Editora, 2024. http://dx.doi.org/10.46898/home.1dc14177-6cd1-468d-a268-6cfd2e6d5ecd.

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Sousa, Ronaldo Costa. "REMINISCÊNCIA, IDENTIDADE E HISTÓRIA: UM ESTUDO DA ESCOLA ESTADUAL VIDAL DE NEGREIROS ATRAVÉS DA FOTOGRAFIA." In Fórum Nacional de Publicações Acadêmicas-Anais-Vol. 03, n. 02, 2024. Home Editora, 2024. http://dx.doi.org/10.46898/home.737b944d-c044-49d1-97ff-b6fcf9e6dd41.

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Souza, Paulo César de. "TRAFICANTES LABORAM NA PREFEITURA E CÂMARA DE VEREADORES OU INÉRCIA DO PODER PÚBLICO EM IBIRITÉ/MG?: breves digressões." In Fórum Nacional de Publicações Acadêmicas-Anais-Vol. 03, n. 02, 2024. Home Editora, 2024. http://dx.doi.org/10.46898/home.3c33e9a0-7523-45e6-9dfe-cfd52c2b059b.

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Sousa, Ronaldo Costa. "A EDUCAÇÃO NO TERRITÓRIO DO AMAPÁ: DESAFIOS E PERSPECTIVAS PARA O DESENVOLVIMENTO." In Fórum Nacional de Publicações Acadêmicas-Anais-Vol. 03, n. 02, 2024. Home Editora, 2024. http://dx.doi.org/10.46898/home.6e7199d3-1bb0-4175-94c5-c4beaa5d26b8.

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Leme, Maicon Douglas. "O PODER JUDICIÁRIO VERSUS A SEGURANÇA PÚBLICA: COMO O ATIVISMO JUDICIAL INTERFERE NO TRABALHO DA POLÍCIA MILITAR." In Fórum Nacional de Publicações Acadêmicas-Anais-Vol. 03, n. 02, 2024. Home Editora, 2024. http://dx.doi.org/10.46898/home.a22afa44-e287-47bf-9d99-3b8eab2d0936.

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Reports on the topic "N-022"

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Ndoye, Aissatou, Khadim Dia, and Racine Ly. The AAgWa Crop Production Forecasts Brief Series - Issue N.02. AKADEMIYA2063, February 2023. http://dx.doi.org/10.54067/acpf.02.

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The Africa Agriculture Watch (AAgWa) Crop Production Brief 2, produced by AKADEMIYA2063, aims to provide more accurate and timely statistics on millet production in Gambia using the Africa Food Crop Production (AfCP) model. The AfCP developed at AKADEMIYA2063 is an artificial intelligence (AI) based forecasting model used to produce yield and harvest forecasts at the beginning of each growing season for nine crops in 47 African countries.
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Ndoye, Aïssatou, Khadim Dia, and Racine Ly. AAgWa Crop Production Forecasts Brief Series - Issue N.02/FR. AKADEMIYA2063, April 2023. http://dx.doi.org/10.54067/acpf.02/fr.

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La Joie, Chad, and Russell Tokuyama. Trusted Delegation of Privileges in an N-Tier Environment (DRAFT 02). Internet2, July 2002. http://dx.doi.org/10.26869/ti.19.1.

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Fortin, R., M. Coyle, J. Buckle, S. W. Hefford, and G. Delaney. Geophysical Series, airborne geophysical survey of the northwestern Athabasca Basin, Saskatchewan, NTS 74 N/02 Cantara Bay. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 2011. http://dx.doi.org/10.4095/289485.

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Camargo Gómez, Fabiola, Carolina Paola Martínez Bernal, Carlos Iván Romero García, and Eduardo Patiño Guerrero. Documentos de Investigación N° 02. Fuerzas Militares de Colombia. Ejército Nacional II División. El conflicto Armado en las Regiones. Claudia Luque Molano, 2017. http://dx.doi.org/10.12804/issne.2590-5260_10336.14124_dicsh.

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Issler, D. R., M. Obermajer, J. Reyes, and M. Li. Integrated analysis of vitrinite reflectance, Rock-Eval 6, gas chromatography, and gas chromatography-mass spectrometry data for the Mallik A-06, Parsons N-10 and Kugaluk N-02 wells, Beaufort-Mackenzie Basin, northern Canada. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 2012. http://dx.doi.org/10.4095/289672.

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Dougherty, B. J., H. J. Abercrombie, A. Achab, R. Bertrand, F. Goodarzi, L. R. Snowdon, and J. Utting. Correlation of Thermal Maturity Indicators For the Tenlen a - 73, Crossley Lake South K - 60, and Kugaluk N - 02 Wells in the northern District of Mackenzie, Northwest Territories. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1991. http://dx.doi.org/10.4095/132644.

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Kabanov, P. B. Revisiting legacy core and cross sections from the sub-Imperial Devonian of Mackenzie River Corridor with emphasis on formation boundaries. Part 1. Wells Kugaluk N-02, Norman Wells P32X, Imperial Bear Island R34X, Maida Creek F57, and Devo Creek P45. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 2013. http://dx.doi.org/10.4095/292866.

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Particle size analysis of core chips from the N. Cook Inlet Unit #A-02 well. Alaska Division of Geological & Geophysical Surveys, December 2014. http://dx.doi.org/10.14509/29171.

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Stratigraphy and vertical hydraulic conductivity of the St. Francois confining unit in townships 25-27 N. and ranges 01-02 W., southeastern Missouri. US Geological Survey, 2001. http://dx.doi.org/10.3133/wri014270.

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