Dissertations / Theses: 'Myogenic'

1

Murnane, Owen D. "Vestibular Evoked Myogenic Potentials." Digital Commons @ East Tennessee State University, 2011. https://dc.etsu.edu/etsu-works/1933.

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Murnane, Owen D. "Vestibular Evoked Myogenic Potentials." Digital Commons @ East Tennessee State University, 2004. https://dc.etsu.edu/etsu-works/1948.

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Murnane, Owen D. "Vestibular Evoked Myogenic Potentials." Digital Commons @ East Tennessee State University, 2005. https://dc.etsu.edu/etsu-works/1947.

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Murnane, Owen D. "Vestibular Evoked Myogenic Potentials." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etsu-works/1932.

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Akin, Faith W. "Vestibular Evoked Myogenic Potentials." Digital Commons @ East Tennessee State University, 2006. https://dc.etsu.edu/etsu-works/2452.

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Akin, Faith W., and Owen D. Murnane. "Vestibular Evoked Myogenic Potentials." Digital Commons @ East Tennessee State University, 2008. https://dc.etsu.edu/etsu-works/1939.

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Murnane, Owen D., and Faith W. Akin. "Vestibular-Evoked Myogenic Potentials." Digital Commons @ East Tennessee State University, 2009. https://dc.etsu.edu/etsu-works/1795.

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Cervical vestibular-evoked myogenic potentials (cVEMPs) are recorded from the sternocleidomastoid muscle using air conduction or bone conduction acoustic stimuli, skull taps, or transmastoid current. The diagnostic usefulness of the cVEMP has been examined for various peripheral and central vestibulopathies. Recent reports indicate that it is possible to record short-latency ocular vestibular-evoked myogenic potentials (oVEMPs) from surface electrodes below the eyes in response to air conduction and bone conduction stimuli. Both methods provide diagnostic information about otolith function. This article provides an overview of each method and highlights the similarities and differences. Several cases are presented to illustrate the relation between the results for cVEMPs and oVEMPs in patients with well-defined audiovestibular disorders.

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Akin, Faith W., and Owen D. Murnane. "Vestibular Evoked Myogenic Potentials." Digital Commons @ East Tennessee State University, 2001. https://dc.etsu.edu/etsu-works/1916.

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Akin, Faith W., and Owen D. Murnane. "Vestibular Evoked Myogenic Potentials." Digital Commons @ East Tennessee State University, 2007. https://dc.etsu.edu/etsu-works/1944.

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Akin, Faith W. "Vestibular Evoked Myogenic Potentials." Digital Commons @ East Tennessee State University, 2007. https://dc.etsu.edu/etsu-works/2450.

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Akin, Faith W., and Owen D. Murnane. "Vestibular Evoked Myogenic Potentials." Digital Commons @ East Tennessee State University, 2000. https://dc.etsu.edu/etsu-works/1920.

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Akin, Faith W., and Owen D. Murnane. "Vestibular Evoked Myogenic Potentials." Digital Commons @ East Tennessee State University, 2006. https://dc.etsu.edu/etsu-works/1945.

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Akin, Faith W., and Owen D. Murnane. "Vestibular Evoked Myogenic Potentials (VEMP)." Digital Commons @ East Tennessee State University, 2004. https://dc.etsu.edu/etsu-works/1797.

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Murnane, Owen D., Faith W. Akin, and T. Medley. "Tone-Evoked Vestibular Myogenic Potentials." Digital Commons @ East Tennessee State University, 2002. https://dc.etsu.edu/etsu-works/1911.

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15

Murnane, Owen D., Faith W. Akin, J. K. Kelly, and J. Tampas. "Ocular Vestibular Evoked Myogenic Potentials." Digital Commons @ East Tennessee State University, 2009. https://dc.etsu.edu/etsu-works/1894.

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16

Akin, Faith W., and Owen D. Murnane. "Vestibular Evoked Myogenic Potentials: Stimulus Parameters." Digital Commons @ East Tennessee State University, 2002. https://dc.etsu.edu/etsu-works/1913.

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17

Murnane, Owen D., Faith W. Akin, J. K. Kelly, and Stephanie M. Byrd. "The Ocular Vestibular Evoked Myogenic Potential." Digital Commons @ East Tennessee State University, 2010. https://dc.etsu.edu/etsu-works/1938.

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18

Akin, Faith W., and Owen Murnane. "Vestibular Evoked Myogenic Potentials: Preliminary Report." Digital Commons @ East Tennessee State University, 2001. https://dc.etsu.edu/etsu-works/1792.

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Vestibular evoked myogenic potentials (VEMPs) are short-latency electromyograms evoked by high-level acoustic stimuli recorded from surface electrodes over the tonically contracted sternocleidomastoid (SCM) muscle. These responses are presumed to originate in the saccule. The purpose of this preliminary report is to provide an overview of our initial experience with the VEMP by describing the responses obtained in five subjects. Click-evoked VEMPs were present at short latencies in two normal-hearing subjects, one patient with profound congenital sensorineural hearing loss, and one patient with a severe sensorineural hearing loss due to Meniere's disease. Additionally, VEMPs were absent in a patient with profound sensorineural hearing loss following removal of a cerebellopontine angle tumor. The amplitude of the VEMP was influenced by the amount of background activity of the SCM muscle, stimulus level, and stimulus frequency. Tone-burst evoked responses showed an inverse relationship between stimulus frequency and response latency. VEMPs may prove to be a reliable technique in the clinical assessment of vestibular function.

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Murnane, Owen D., Faith W. Akin, J. K. Kelly, Stephanie M. Byrd, and A. Pearson. "The Ocular Vestibular Evoked Myogenic Potential." Digital Commons @ East Tennessee State University, 2011. https://dc.etsu.edu/etsu-works/1934.

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Murnane, Owen D., Faith W. Akin, J. K. Kelly, Stephanie M. Byrd, and A. Pearson. "The Ocular Vestibular Evoked Myogenic Potential." Digital Commons @ East Tennessee State University, 2010. https://dc.etsu.edu/etsu-works/1935.

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21

Murnane, Owen D., and Faith W. Akin. "Vestibular Evoked Myogenic Potentials: Recording Methods." Digital Commons @ East Tennessee State University, 2002. https://dc.etsu.edu/etsu-works/1912.

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22

Vaughn, Mathew Alan. "Characterization of intra-litter variation on myogenic development and myogenic progenitor cell response to growth promoting stimuli." Diss., Kansas State University, 2016. http://hdl.handle.net/2097/34595.

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Doctor of Philosophy
Department of Animal Sciences and Industry
John M. Gonzalez
This series of studies focuses on the impact of intra-litter variation on fetal myogenesis, and the ability of porcine progenitor cells to respond to growth promoting stimuli. In study 1, the smallest (SM), median (ME), and largest (LG) male fetuses from each litter were selected for muscle morphometric analysis from gilts at d-60 ± 2 and 95 ± 2 of gestation. On d-60 and 95 of gestation LG fetuses had greater whole muscle cross-sectional area (CSA) than ME and SM fetuses, and ME fetuses had greater whole muscle CSA than SM fetuses. Indicating that SM and ME fetuses are on a delayed trajectory for myogenesis compared to LG fetuses. At d-60 the advanced trajectory of LG compared to ME fetuses was due to increased development of secondary muscle fibers; whereas, the advanced myogenic development of LG and ME fetuses compared to SM fetuses was due to the presence of fewer primary and secondary muscle fibers. At d-95 of gestation the advanced myogenic development of LG and ME was due to increased hypertrophy of secondary muscle fibers. For study 2, porcine fetal myoblasts (PFM) were isolated from SM, ME, and LG fetuses from d-60 ± 2 of gestation fetuses and for study 3, porcine satellite cells (PSC) were isolated from the piglet nearest the average body weight of the litter. Both myogenic cell types were utilized to evaluate effects of porcine plasma on proliferation, differentiation, and indications of protein synthesis. For the proliferation assay, cells were exposed to one of three treatments: high serum which consisted high-glucose Dulbecco's Modified Eagle Medium supplemented with 10% (vol/vol) fetal bovine serum, 2% (vol/vol) porcine serum, 100 U penicillan/mL, 100 µg of strepmycin/mL, and 20 µg of gentamicin/mL (HS), low serum which consisted of HS without 10% FBS (LS), and LS supplemented with 10% (wt/vol) porcine plasma (PP). Treatments for the differentiation and protein synthesis assays consisted of either HS or LS media that either contained porcine plasma at 10% (wt/vol; PPP) or 0% (wt/vol; PPN). The HS-PFM had a greater proliferation rate compared to the LS and PP-PFM, and PP-PFM had a greater proliferation rate compared to LS-PFM. The LG fetuses’ PFM had a reduced proliferation rate compared to SM and ME fetuses’ PFM, which were similar. The PPP-PFM had a decreased myotube diameter compared to PPN-PFM. Small fetuses’ PFM had a greater myotube diameter compared to ME and LG fetuses’ PFM, and ME fetuses’ PFM had a greater myotube diameter compared to LG fetuses’ PFM. The proliferation rate of PP-PSC was decreased compared to the HS- and LS-PSC, and HS-PSC had a greater proliferation rate compared to LS-PSC. The PPP-PSC had greater differentiation capacity and myotube diameter than PPN-PSC. In conjunction these results indicate divergent myogenic development among different fetal sizes within a litter and suggest that porcine plasma supplementation stimulates myogenic progenitor cell activity in an age specific manner.

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Ostrovska, Alexsandra. "Vestibular evoked myogenic potentials in clinical applications." Thesis, McGill University, 2004. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=80345.

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It is uncertain whether clinically useful information of otolith function can be well characterized by vestibular-evoked-myogenic-potentials (VEMPs), i.e., electromyogenic activity recorded from sternomastoid muscles in response to brief loud auditory clicks. We aimed to assess the utility of VEMP testing in the differential diagnosis of dizziness (81 dizzy patients, 12 normals). We found that: (1) VEMP was reliably elicited from all controls and from 96% of patients without loss of vestibular function; (2) in patients with documented unilateral peripheral vestibular disorders, VEMP could reveal loss of otolith function that usefully facilitated diagnoses; and (3) such otolith function loss was independent of canal function loss revealed by caloric testing. We conclude that the VEMP-test is clinically useful to assess vestibular (otolith and/or inferior vestibular nerve) function, providing information complementary to that obtained from caloric testing (horizontal semicircular canal and/or superior vestibular nerve function).

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Murnane, Owen D., Faith W. Akin, J. K. Kelly, Stephanie M. Byrd, and A. Pearson. "Bone Conduction Ocular Vestibular Evoked Myogenic Potentials." Digital Commons @ East Tennessee State University, 2011. https://dc.etsu.edu/etsu-works/1890.

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25

Murnane, Owen D., and Faith W. Akin. "Vestibular Evoked Myogenic Potentials: I. Recording Methods." Digital Commons @ East Tennessee State University, 2001. https://dc.etsu.edu/etsu-works/1917.

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26

Akin, Faith W., Owen D. Murnane, and T. Medley. "Clinical Application of Vestibular Evoked Myogenic Potentials." Digital Commons @ East Tennessee State University, 2002. https://dc.etsu.edu/etsu-works/1910.

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27

Akin, Faith W., Owen D. Murnane, and T. Medley. "Vestibular Evoked Myogenic Potentials Using Tonal Stimuli." Digital Commons @ East Tennessee State University, 2002. https://dc.etsu.edu/etsu-works/1914.

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Akin, Faith W., Owen D. Murnane, and T. Medley. "Vestibular Evoked Myogenic Thresholds Using Tonal Stimuli." Digital Commons @ East Tennessee State University, 2002. https://dc.etsu.edu/etsu-works/2469.

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29

Jullian, Estelle. "Myogenic fate choice in the cardiopharyngeal mesoderm." Thesis, Aix-Marseille, 2019. http://www.theses.fr/2019AIXM0363.

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Le mésoderme cardiopharyngé (CPM) est localisé au niveau crânial de l’embryon de souris, et contribue aux muscles de la tête et du cou, dérivés des arcs pharyngés, et aux cellules progénitrices du second champ cardiaque qui donne naissance au muscle cardiaque. L’étude du CPM permet de comprendre les malformations congénitales cardiaques et crâniofaciales, comme celles observées chez les patients atteints du syndrome de microdélétion 22q11.2. Chez la souris, une analyse de clonale rétrospective a établi qu’il existe une relation clonale entre certaines parties du cœur, dérivant du second champ cardiaque et certains muscles branchiomériques. Bien que, chez le protochordé Ciona, une cellule progénitrice du CPM a été identifiée, capable de contribuer au cœur et aux muscles squelettiques pharyngés, les cellules progénitrices communes entre le cœur et les muscles de la tête n’ont pas été localisées dans l’embryon de souris. L’objectif de ma thèse consiste à étudier le destin du cœur contre celui des muscles de la tête dans le CPM. Le premier chapitre des résultats adresse la localisation spatiotemporelle des potentielles cellules progénitrices bipotentes du cœur et des muscles de la tête dans le CPM murin et comment elles sont régulées. Les résultats démontrent que bien que les composants conservés soient présents, leur régulation diffère entre la souris et Ciona. Le second et le troisième chapitres de résultats présentent une analyse de l’hétérogénéité à l’intérieur du CPM et entre les arcs pharyngés. Des domains ont été déterminés dans les arcs, et le destin cellulaire reste à explorer
Cardiopharyngeal mesoderm is localized at the cranial level of the mouse embryo, and contributes to head and neck muscles, derived from pharyngeal arches, and cardiac muscle. Study cardiopharyngeal mesoderm allows to understand some congenital abnormalities, which have cardiac and craniofacial defects, like DiGeorge syndrome. In mouse, retrospective clonal analysis allows to determinate a relationship between second heart field and specific branchiomeric muscles. Each pharyngeal arch gives rise to a specific branchiomeric muscles group which is linked to a part of the heart. Indeed, it has been showed in Chordates, a progenitor cell which is able to contribute to the heart and head muscles. My thesis objective is to investigate heart versus head muscles fate in cardiopharyngeal mesoderm. I wanted to understand the mechanism underlying heart and head muscles specification. The first part of the thesis will undercover the localization and the timeline of the potential bipotent myogenic progenitor cells present in cardiopharyngeal mesoderm and how they are regulated. The results showed that the conserved components are present but the regulation between each component seemed to be different in the mouse compared to Ciona. The second part and the three part of the thesis will undercover the heterogeneity intra- and inter-pharyngeal arches. Domains through the core of the arches could be observed and the fate of each domain needs to be explored

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30

Meyer, Christopher. "Mathematical models for vasomotion and the myogenic response." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ59847.pdf.

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31

Maguire, Richard John. "Identifying targets of MyoD in myogenic stem cells." Thesis, University of York, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.516609.

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32

Hamed, Munerah. "Effect of p300 HAT Activity on Myogenic Differentiation." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/23707.

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Skeletal muscle specification and differentiation programs are regulated by the myogenic regulatory factors which include Myf5, MyoD, myogenin and Mrf4. Upstream of the MRFs, the transcription co-activators and other intracellular and extracellular signals play crucial roles in regulating skeletal myogenesis. Histone acetyltransferase activity of p300 is required for Myf5 and MyoD expression. Furthermore, the MyoD core enhancer region is indispensable for MyoD expression. However, the mechanism by which p300 activates MyoD gene expression is to be determined. The histone acetyltransferase activity of p300 can be inhibited by small molecule inhibitors such as curcumin. Thus, using the inhibitor approach on stem cells is useful to investigate the role of p300 in activating MyoD expression during myogenesis. We here show that curcumin was able to inhibit stem cell determination and differentiation into skeletal myocytes. We also show that p300 is present, and histone acetylation is high at the core enhancer region. Therefore, we provide evidence that p300 is directly involved in MyoD gene expression during skeletal myogenesis.

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33

Antoni, Laurent Paul. "The regulation of myogenic differentiation by WNT signalling." Thesis, King's College London (University of London), 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.414996.

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34

Akin, Faith W., Owen D. Murnane, J. Tampas, and C. Clinard. "Air and Bone-Conducted Vestibular Evoked Myogenic Potentials." Digital Commons @ East Tennessee State University, 2005. https://dc.etsu.edu/etsu-works/1906.

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35

Khilji, Saadia. "Dissecting the Epigenetic Signaling Underlying Early Myogenic Differentiation." Thesis, Université d'Ottawa / University of Ottawa, 2021. http://hdl.handle.net/10393/42092.

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36

Zainalabidin, Satirah. "The role of adventitia in pressure-dependent myogenic tone." Thesis, University of Strathclyde, 2011. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=15577.

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37

Anakwe, Kelly Uzoaru. "The role of Wnt signalling in limb myogenic differentiation." Thesis, King's College London (University of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271610.

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Wang, Kepeng. "The involvement of JAK2/STAT2/STAT3 in myogenic differentiation /." View abstract or full-text, 2008. http://library.ust.hk/cgi/db/thesis.pl?BICH%202008%20WANGK.

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39

Akin, Faith W., and Owen D. Murnane. "The Clinical Application of the Vestibular Evoked Myogenic Potentials." Digital Commons @ East Tennessee State University, 2005. https://dc.etsu.edu/etsu-works/1946.

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40

Akin, Faith W. "Clinical Perspectives in Audiology: Cervical Vestibular Evoked Myogenic Potentials." Digital Commons @ East Tennessee State University, 2010. https://dc.etsu.edu/etsu-works/2442.

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This session was developed by Special Interest Division #6: Hearing & Hearing Disorders. Cervical vestibular evoked myogenic potentials (cVEMP) supplement the current vestibular test battery by providing diagnostic information about saccular and/ or inferior vestibular nerve function. The session will provide background, recording method, and clinical application of the cVEMP

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41

Prakash, Srinivasamurthy Ravi. "Vestibular Evoked Myogenic Potentials : physiology, variability, and statistical characteristics." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/54587.

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Thesis (Ph. D.)--Harvard-MIT Division of Health Sciences and Technology, 2009.
Cataloged from PDF version of thesis.
Includes bibliographical references.
Vestibular Evoked Myogenic Potentials (VEMPs) are electrical signals recorded from the skin overlying skeletal muscles of the head and neck in response to high-intensity acoustic stimuli. VEMPs have been observed in stimulus locked averages of the electromyogram in a majority of human subjects, and are thought to originate in the otolith organs of the inner ear, which are balance organs responsible for sensing acceleration and orientation with respect to gravity. Otolith reflexes interact with the motor drive to a contracted muscle to give rise to the VEMP signal. In the last few years these signals have been used in the clinic as an indicator of peripheral vestibular function and a test based on VEMP from neck muscles (cervical, or cVEMP) is currently the only clinically feasible means of assessing the functioning of the saccule and its innervation. However, the usefulness of the test is limited by the inter-subject and test-retest variability of the response, and the unclear relationship between specific response features and vestibular pathophysiology. In this thesis, our goal is to measure VEMP variability, assess the influence of non-vestibular factors on the VEMP, and to develop a signal processing strategy to estimate response parameters that are both statistically stable, and physiologically meaningful. In the first part of the thesis, we systematically measure VEMPs from a small clinically normal population, and quantify the variability of the response, particularly the dependence on contraction effort. We also assess approaches to normalizing the response by estimates of the effort.
(cont.) In the second part of the thesis, we develop a computational model of VEMP physiology, and use the model to separate external sources of variability from internal noise. The model outputs are also used to define a statistical measure, the inverse coefficient of variation (iCOV), which correlates with altered vestibular sensitivity, but is relatively robust to other changes. When applied to the experimental data, the iCOV is found to yield estimates of vestibular sensitivity that are more stable than the conventional VEMP amplitude. This measure also reveals a diversity of response threshold and growth characteristics within the clinically normal population. These findings suggest that the proposed approach could lead to the development of an improved clinical tool, but could also yield new insights into the physiological mechanisms of vestibular pathology.
by Srinivasamurthy Ravi Prakash.
Ph.D.

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42

Hamed, Munerah. "Characterization of the Epigenetic Signature Underlying Early Myogenic Differentiation." Thesis, Université d'Ottawa / University of Ottawa, 2019. http://hdl.handle.net/10393/39559.

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Although skeletal myogenesis is largely controlled by myogenic regulatory factors, epigenetic modifications have recently emerged as an essential regulatory mechanism of gene expression. Molecular regulation of stem cell differentiation is exerted through both genetic and epigenetic factors over distal enhancer regions. Understanding the mechanistic action of active or poised enhancers is therefore, imperative for the control of stem cell differentiation. Based on the genome-wide co-occurrence of different epigenetic marks in proliferating myoblasts, we have generated a chromatin state model to profile differentiation- and rexinoid-responsive histone acetylation in early myoblast differentiation. Here, we delineate the functional mode of transcription regulators during early myogenic differentiation using genome-wide chromatin state association. We define a role of transcriptional coactivator p300, when recruited by muscle master regulator MyoD, in the establishment and regulation of myogenic loci at the onset of myoblast differentiation. In addition, we reveal an enrichment of loci-specific histone acetylation at p300 associated active or poised enhancers, mainly when enlisted by MyoD. We have previously established that bexarotene, a clinically approved agonist of retinoid X receptor (RXR), promotes the specification and differentiation of skeletal muscle lineage. Hence, we investigated the genome-wide impact of rexinoids on myogenic differentiation and uncovered a new mechanism of rexinoid action, which is mediated by the nuclear receptor and largely reconciled through direct regulation of MyoD gene expression. In addition, we determined rexinoid-responsive residue-specific histone acetylation at a distinct chromatin state associated with MyoD and myogenin. Finally, through ChIP-seq and RNA-seq analyses, we have identified dystroglycan (Dag1) as a differentiation-dependent and a rexinoid-responsive model target, and we revealed a possible co-regulation of Dag1 by p300 and MyoD accompanied by enrichment of loci-specific histone acetylation. Taken together, we provide novel molecular insights into the regulation of myogenic enhancers by p300 in concert with MyoD. Furthermore, we provide novel mechanistic perceptions into the interplay between RXR signaling and chromatin states pertinent to myogenic programs in early myoblast differentiation. Our studies present a valuable insight for driving condition-specific chromatin state or enhancers pharmacologically to treat muscle-related diseases and for the identification of additional myogenic targets and molecular interactions for therapeutic development.

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43

Raina, Hema, and hemaraina@yahoo com. "Functional significance of sodium calcium exchange in arteriolar myogenic zone." RMIT University. Medical Sciences, 2006. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20080812.155348.

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To determine a possible role for NCX in myogenically active smooth muscle arterioles, studies were conducted by manipulation of extracellular Na+ levels and inhibition of the exchanger. Western blotting was performed for the identification of the NCX protein. Real-time PCR was performed to demonstrate the level of expression of mRNA, for the NCX isoforms. Antisense oligonucleotides against NCX mRNA were introduced in an isolated cremaster arteriole followed by functional studies after 24 hours. Level of expression of NCX was determined by western blotting. The data are consistent with the presence of NCX1 in the cremaster arterioles.

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44

Osborn, Dan. "Regulation of myogenic bHLH proteins during zebrafish slow muscle development." Thesis, King's College London (University of London), 2008. https://kclpure.kcl.ac.uk/portal/en/theses/regulation-of-myogenic-bhlh-proteins-during-zebrafish-slow-muscle-development(80efc981-2fb8-47c3-a63b-8fd433f7f487).html.

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45

Colegrave, Melanie. "Expression of #beta#-cardiac myosin in a myogenic cell line." Thesis, King's College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.342254.

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46

Akin, Faith W., and Owen D. Murnane. "Update on the Clinical Utility of Vestibular Evoked Myogenic Potentials." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etsu-works/1881.

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Vestibular-evoked myogenic potentials (VEMPs) supplement the vestibular test battery by providing diagnostic information about otolith organ function. The purpose of this presentation is to provide an update on the clinical use of the cervical VEMP and ocular VEMP as clinical tests of otolith function

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47

Murnane, Owen D., Faith W. Akin, J. K. Kelly, Stephanie M. Byrd, and A. Pearson. "Comparative Properties of Cervical and Ocular Vestibular Evoked Myogenic Potentials." Digital Commons @ East Tennessee State University, 2012. https://dc.etsu.edu/etsu-works/1886.

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48

Fillon, S., Faith W. Akin, and Owen D. Murnane. "A Comparison of Recording Techniques for Vestibular Evoked Myogenic Potentials." Digital Commons @ East Tennessee State University, 2004. https://dc.etsu.edu/etsu-works/1909.

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49

Furutani, Yuma. "Effects of Magnesium Deficiency on Expression of Myogenic Regulatory Factors." Kyoto University, 2011. http://hdl.handle.net/2433/142329.

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Kyoto University (京都大学)
0048
新制・課程博士
博士(農学)
甲第16131号
農博第1867号
新制||農||989(附属図書館)
学位論文||H23||N4601(農学部図書室)
28710
京都大学大学院農学研究科応用生物科学専攻
(主査)教授松井徹, 教授祝前博明, 教授今井裕
学位規則第4条第1項該当

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50

Fife, Terry D., James G. Colebatch, Kevin A. Kerber, Krister Brantberg, Michael Strupp, Hyung Lee, Mark F. Walker, et al. "Practice guideline: Cervical and ocular vestibular evoked myogenic potential testing." LIPPINCOTT WILLIAMS & WILKINS, 2017. http://hdl.handle.net/10150/626461.

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Objective: To systematically review the evidence and make recommendations with regard to diagnostic utility of cervical and ocular vestibular evoked myogenic potentials (cVEMP and oVEMP, respectively). Four questions were asked: Does cVEMP accurately identify superior canal dehiscence syndrome (SCDS)? Does oVEMP accurately identify SCDS? For suspected vestibular symptoms, does cVEMP/oVEMP accurately identify vestibular dysfunction related to the saccule/utricle? For vestibular symptoms, does cVEMP/oVEMP accurately and substantively aid diagnosis of any specific vestibular disorder besides SCDS? Methods: The guideline panel identified and classified relevant published studies (January 1980-December 2016) according to the 2004 American Academy of Neurology process. Results and Recommendations: Level C positive: Clinicians may use cVEMP stimulus threshold values to distinguish SCDS from controls (2 Class III studies) (sensitivity 86%-91%, specificity 90%-96%). Corrected cVEMP amplitude may be used to distinguish SCDS from controls (2 Class III studies) (sensitivity 100%, specificity 93%). Clinicians may use oVEMP amplitude to distinguish SCDS from normal controls (3 Class III studies) (sensitivity 77%-100%, specificity 98%-100%). oVEMP threshold may be used to aid in distinguishing SCDS from controls (3 Class III studies) (sensitivity 70%-100%, specificity 77%-100%). Level U: Evidence is insufficient to determine whether cVEMP and oVEMP can accurately identify vestibular function specifically related to the saccule/utricle, or whether cVEMP or oVEMP is useful in diagnosing vestibular neuritis or Meniere disease. Level C negative: It has not been demonstrated that cVEMP substantively aids in diagnosing benign paroxysmal positional vertigo, or that cVEMP or oVEMP aids in diagnosing/managing vestibular migraine.

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Dissertations / Theses on the topic 'Myogenic'

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