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1

Maros, Kathleen. "Myalgic encephalomyelitis?" Medical Journal of Australia 148, no. 8 (April 1988): 424. http://dx.doi.org/10.5694/j.1326-5377.1988.tb115981.x.

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2

Lev, M. "Myalgic Encephalomyelitis." Journal of the Royal Society of Medicine 82, no. 11 (November 1989): 693–94. http://dx.doi.org/10.1177/014107688908201127.

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3

Rosen, S. D., J. C. King, and P. G. F. Nixon. "Myalgic Encephalomyelitis." Journal of the Royal Society of Medicine 83, no. 3 (March 1990): 199. http://dx.doi.org/10.1177/014107689008300336.

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4

Hodson, A. D. "Myalgic Encephalomyelitis." Journal of the Royal Society of Medicine 83, no. 3 (March 1990): 199–200. http://dx.doi.org/10.1177/014107689008300337.

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5

Wessely, S. "Myalgic Encephalomyelitis." Journal of the Royal Society of Medicine 84, no. 3 (March 1991): 182–83. http://dx.doi.org/10.1177/014107689108400338.

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6

Gordon, Neil. "Myalgic Encephalomyelitis." Developmental Medicine & Child Neurology 30, no. 5 (November 12, 2008): 677–82. http://dx.doi.org/10.1111/j.1469-8749.1988.tb04808.x.

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7

Hartnell, L. "Myalgic encephalomyelitis." BMJ 298, no. 6687 (June 10, 1989): 1577–78. http://dx.doi.org/10.1136/bmj.298.6687.1577-b.

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8

Wookey, C. "Myalgic encephalomyelitis." BMJ 298, no. 6687 (June 10, 1989): 1578. http://dx.doi.org/10.1136/bmj.298.6687.1578.

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9

Walker, R. G. "Myalgic encephalomyelitis." BMJ 298, no. 6687 (June 10, 1989): 1578. http://dx.doi.org/10.1136/bmj.298.6687.1578-a.

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10

Staines, Donald. "Myalgic encephalomyelitis hypothesis." Medical Journal of Australia 143, no. 2 (July 1985): 91. http://dx.doi.org/10.5694/j.1326-5377.1985.tb122819.x.

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11

Marshall-Gradisnik, Sonya, and Natalie Eaton-Fitch. "Understanding myalgic encephalomyelitis." Science 377, no. 6611 (September 9, 2022): 1150–51. http://dx.doi.org/10.1126/science.abo1261.

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12

Byrne, Edward. "In Reply: Myalgic encephalomyelitis?" Medical Journal of Australia 148, no. 8 (April 1988): 424. http://dx.doi.org/10.5694/j.1326-5377.1988.tb115982.x.

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13

Holborow, P. L., and Edward Byrne. "Pathophysiology of myalgic encephalomyelitis." Medical Journal of Australia 148, no. 11 (June 1988): 598. http://dx.doi.org/10.5694/j.1326-5377.1988.tb93822.x.

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14

Jason, Leonard A., Dylan Damrongvachiraphan, Jessica Hunnell, Lindsey Bartgis, Abigail Brown, Meredyth Evans, and Molly Brown. "Myalgic Encephalomyelitis Case Definitions." Automatic Control of Physiological State and Function 1 (2012): 1–14. http://dx.doi.org/10.4303/acpsf/k110601.

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15

Lynch, Sean, and Ram Seth. "Depression and Myalgic Encephalomyelitis." Journal of the Royal Society of Medicine 83, no. 5 (May 1990): 341. http://dx.doi.org/10.1177/014107689008300528.

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16

Page, Margaret. "Myalgic Encephalomyelitis — Physiotherapy Treatments." Physiotherapy 74, no. 7 (July 1988): 329. http://dx.doi.org/10.1016/s0031-9406(10)63233-6.

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17

Bass, Christopher. "Does myalgic encephalomyelitis exist?" Lancet 357, no. 9271 (June 2001): 1889. http://dx.doi.org/10.1016/s0140-6736(00)05001-7.

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18

van Houdenhove, Boudewijn. "Does myalgic encephalomyelitis exist?" Lancet 357, no. 9271 (June 2001): 1889. http://dx.doi.org/10.1016/s0140-6736(00)05002-9.

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19

Grossman, Elmer R. "Does myalgic encephalomyelitis exist?" Lancet 357, no. 9271 (June 2001): 1889–90. http://dx.doi.org/10.1016/s0140-6736(00)05003-0.

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20

Speight, Nigel, and Alan Franklin. "Does myalgic encephalomyelitis exist?" Lancet 357, no. 9271 (June 2001): 1890. http://dx.doi.org/10.1016/s0140-6736(00)05004-2.

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21

Ramsey, A. Melvin, AnthonyS David, Simon Wessely, AnthonyJ Pelosi, and E. G. Dowsett. "MYALGIC ENCEPHALOMYELITIS, OR WHAT?" Lancet 332, no. 8602 (July 1988): 100–101. http://dx.doi.org/10.1016/s0140-6736(88)90028-1.

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22

Lloyd, Andrew, David Abi Hanna, and Denis Wakefield. "INTERFERON AND MYALGIC ENCEPHALOMYELITIS." Lancet 331, no. 8583 (February 1988): 471. http://dx.doi.org/10.1016/s0140-6736(88)91259-7.

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23

Lloyd, A. R., D. Wakefield, C. Boughton, and J. Dwyer. "WHAT IS MYALGIC ENCEPHALOMYELITIS?" Lancet 331, no. 8597 (June 1988): 1286–87. http://dx.doi.org/10.1016/s0140-6736(88)92107-1.

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24

Mouterde, Olivier. "Myalgic encephalomyelitis in children." Lancet 357, no. 9255 (February 2001): 562. http://dx.doi.org/10.1016/s0140-6736(05)71716-5.

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25

Shepherd, C. "Myalgic encephalomyelitis by proxy." BMJ 299, no. 6706 (October 21, 1989): 1030–31. http://dx.doi.org/10.1136/bmj.299.6706.1030-c.

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26

MURDOCH, J. C. "The Myalgic Encephalomyelitis Syndrome." Family Practice 5, no. 4 (1988): 302–6. http://dx.doi.org/10.1093/fampra/5.4.302.

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27

Williams, Ashley Mai, Gary Christopher, and Elizabeth Jenkinson. "The psychological impact of dependency in adults with chronic fatigue syndrome/myalgic encephalomyelitis: A qualitative exploration." Journal of Health Psychology 24, no. 2 (April 19, 2016): 264–75. http://dx.doi.org/10.1177/1359105316643376.

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Chronic fatigue syndrome/myalgic encephalomyelitis can limit functional capacity, producing various degrees of disability and psychological distress. Semi-structured interviews explored the experiences of adults with chronic fatigue syndrome/myalgic encephalomyelitis being physically dependent on other people for help in daily life, and whether physical dependency affects their psychological well-being. Thematic analysis generated six themes: loss of independence and self-identity, an invisible illness, anxieties of today and the future, catch-22, internalised anger, and acceptance of the condition. The findings provide insight into the psychological impact of dependency. Implications for intervention include better education relating to chronic fatigue syndrome/myalgic encephalomyelitis for family members, carers, and friends; ways to communicate their needs to others who may not understand chronic fatigue syndrome/myalgic encephalomyelitis; and awareness that acceptance of the condition could improve psychological well-being.
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28

A. Jason, Leonard, Marcie L. Zinn, and Mark A. Zinn. "Myalgic Encephalomyelitis: Symptoms and Biomarkers." Current Neuropharmacology 13, no. 5 (October 13, 2015): 701–34. http://dx.doi.org/10.2174/1570159x13666150928105725.

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29

Speight, Nigel. "Myalgic Encephalomyelitis‐Time to repent." Acta Paediatrica 109, no. 4 (February 22, 2020): 862. http://dx.doi.org/10.1111/apa.15181.

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30

HOYEN, D. "MYALGIC ENCEPHALOMYELITIS AND ALPHA-INTERFERON." Lancet 331, no. 8577 (January 1988): 125. http://dx.doi.org/10.1016/s0140-6736(88)90329-7.

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31

Goudsmit, E. M., B. Stouten, and S. Howes. "Illness Intrusiveness in Myalgic Encephalomyelitis." Journal of Health Psychology 14, no. 2 (March 2009): 215–21. http://dx.doi.org/10.1177/1359105308100205.

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32

Carruthers, Bruce M., Anil Kumar Jain, Kenny L. De Meirleir, Daniel L. Peterson, Nancy G. Klimas, A. Martin Lerner, Alison C. Bested, et al. "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome." Journal of Chronic Fatigue Syndrome 11, no. 1 (January 2003): 7–115. http://dx.doi.org/10.1300/j092v11n01_02.

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33

Shepherd, C. "Intravenous immunoglobulin and myalgic encephalomyelitis." BMJ 303, no. 6804 (September 21, 1991): 716. http://dx.doi.org/10.1136/bmj.303.6804.716-c.

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34

Coakley, J. H. "Myalgic encephalomyelitis and muscle fatigue." BMJ 298, no. 6689 (June 24, 1989): 1711–12. http://dx.doi.org/10.1136/bmj.298.6689.1711-c.

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35

Carruthers, B. M., M. I. van de Sande, K. L. De Meirleir, N. G. Klimas, G. Broderick, T. Mitchell, D. Staines, et al. "Myalgic encephalomyelitis: International Consensus Criteria." Journal of Internal Medicine 270, no. 4 (August 22, 2011): 327–38. http://dx.doi.org/10.1111/j.1365-2796.2011.02428.x.

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36

Devendorf, Andrew R., Carly T. Jackson, Madison Sunnquist, and Leonard A. Jason. "Approaching recovery from myalgic encephalomyelitis and chronic fatigue syndrome: Challenges to consider in research and practice." Journal of Health Psychology 24, no. 10 (November 28, 2017): 1412–24. http://dx.doi.org/10.1177/1359105317742195.

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There are unique methodological challenges to studying and assessing recovery in myalgic encephalomyelitis and chronic fatigue syndrome. This study explored these challenges through interviewing 13 physicians who treat myalgic encephalomyelitis and chronic fatigue syndrome. Our deductive thematic analysis produced four themes to consider when approaching recovery: lifespan differences in the illness experience; the heterogeneity of myalgic encephalomyelitis and chronic fatigue syndrome—case definitions, etiological stance, and misdiagnosis; patient follow-up and selection bias; and assessment logistics. We discuss how researchers and clinicians can use these considerations when working with patients, drafting recovery criteria, and interpreting treatment outcomes.
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37

Brown, Abigail, and Leonard A. Jason. "Meta-analysis investigating post-exertional malaise between patients and controls." Journal of Health Psychology 25, no. 13-14 (July 5, 2018): 2053–71. http://dx.doi.org/10.1177/1359105318784161.

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Post-exertional malaise is either required or included in many previously proposed case definitions of myalgic encephalomyelitis/chronic fatigue syndrome. A meta-analysis of odds ratios (ORs; association between patient status and post-exertional malaise status) and a number of potential moderators (i.e. study-level characteristics) of effect size were conducted. Post-exertional malaise was found to be 10.4 times more likely to be associated with a myalgic encephalomyelitis/chronic fatigue syndrome diagnosis than with control status. Significant moderators of effect size included patient recruitment strategy and control selection. These findings suggest that post-exertional malaise should be considered a cardinal symptom of myalgic encephalomyelitis/chronic fatigue syndrome.
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38

Jason, Leonard A., Abigail Brown, Erin Clyne, Lindsey Bartgis, Meredyth Evans, and Molly Brown. "Contrasting Case Definitions for Chronic Fatigue Syndrome, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Myalgic Encephalomyelitis." Evaluation & the Health Professions 35, no. 3 (December 7, 2011): 280–304. http://dx.doi.org/10.1177/0163278711424281.

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39

O’connor, Kelly, Madison Sunnquist, Laura Nicholson, Leonard A. Jason, Julia L. Newton, and Elin B. Strand. "Energy envelope maintenance among patients with myalgic encephalomyelitis and chronic fatigue syndrome: Implications of limited energy reserves." Chronic Illness 15, no. 1 (December 12, 2017): 51–60. http://dx.doi.org/10.1177/1742395317746470.

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Objective The Energy Envelope Theory of myalgic encephalomyelitis and chronic fatigue syndrome postulates that individuals with myalgic encephalomyelitis and chronic fatigue syndrome may experience some increase in functioning if their level of exertion consistently remains within the limits of their available energy. Findings of several studies support this theory; however, the current study is the first to explore how an individual’s initial level of available energy may influence the relation between energy envelope maintenance and level of functioning. Method The functioning, activity, and symptomatology of six groups of individuals with myalgic encephalomyelitis and chronic fatigue syndrome were compared. Groups were created based upon level of available energy (higher or lower) and energy envelope adherence (underextended, within, overextended). Results Results indicate that, as expected, individuals with myalgic encephalomyelitis and chronic fatigue syndrome who had higher available energy also had better functioning than individuals with lower available energy; however, this relation was less pronounced for individuals who were overexerting themselves. Discussion These results are consistent with the Energy Envelope Theory, and they suggest that overexertion was particularly impactful for individuals with higher levels of available energy.
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40

Jason, Leonard, Kristen Barker, and Abigail Brown. "Pediatric Myalgic Encephalomyelitis/Chronic Fatigue Syndrome." Reviews in Health Care 3, no. 4 (October 12, 2012): 257. http://dx.doi.org/10.7175/rhc.28034257-270.

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Research on pediatric Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is reviewed in this article. Many recent articles in this area highlight the existence of key differences between the adult and pediatric forms of the illness. This review article provides an overview of pediatric ME/ CFS, including epidemiology, diagnostic criteria, treatment, and prognosis. Challenges to the field are identified with the hope that in the future pediatric cases of ME/CFS can be more accurately diagnosed and successfully managed.
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41

Jason, Leonard, Kristen Barker, and Abigail Brown. "Pediatric Myalgic Encephalomyelitis/Chronic Fatigue Syndrome." Reviews in Health Care 3, no. 4 (October 12, 2012): 257–70. http://dx.doi.org/10.7175/rhc.v3i4.280.

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Research on pediatric Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is reviewed in this article. Many recent articles in this area highlight the existence of key differences between the adult and pediatric forms of the illness. This review article provides an overview of pediatric ME/ CFS, including epidemiology, diagnostic criteria, treatment, and prognosis. Challenges to the field are identified with the hope that in the future pediatric cases of ME/CFS can be more accurately diagnosed and successfully managed.
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42

Crowhurst, Greg. "Supporting people with severe myalgic encephalomyelitis." Nursing Standard 19, no. 21 (February 2, 2005): 38–43. http://dx.doi.org/10.7748/ns.19.21.38.s50.

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43

Crowhurst, Greg. "Supporting people with severe myalgic encephalomyelitis." Nursing Standard 19, no. 21 (February 2, 2005): 38–43. http://dx.doi.org/10.7748/ns2005.02.19.21.38.c3796.

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44

Muirhead, Nina, John Muirhead, Grace Lavery, and Ben Marsh. "Medical School Education on Myalgic Encephalomyelitis." Medicina 57, no. 6 (May 28, 2021): 542. http://dx.doi.org/10.3390/medicina57060542.

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Background and objectives: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex multi-system disease with a significant impact on the quality of life of patients and their families, yet the majority of ME/CFS patients go unrecognised or undiagnosed. For two decades, the medical education establishment in the UK has been challenged to remedy these failings, but little has changed. Meanwhile, there has been an exponential increase in biomedical research and an international paradigm shift in the literature, which defines ME/CFS as a multisystem disease, replacing the psychogenic narrative. This study was designed to explore the current UK medical school education on ME/CFS and to identify challenges and opportunities relating to future ME/CFS medical education. Materials and methods: A questionnaire, developed under the guidance of the Medical Schools Council, was sent to all 34 UK medical schools to collect data for the academic year 2018–2019. Results: Responses were provided by 22 out of a total of 34 medical schools (65%); of these 13/22 (59%) taught ME/CFS, and teaching was led by lecturers from ten medical specialties. Teaching delivery was usually by lecture; discussion, case studies and e-learning were also used. Questions on ME/CFS were included by seven schools in their examinations and three schools reported likely clinical exposure to ME/CFS patients. Two-thirds of respondents were interested in receiving further teaching aids in ME/CFS. None of the schools shared details of their teaching syllabus, so it was not possible to ascertain what the students were being taught. Conclusions: This exploratory study reveals inadequacies in medical school teaching on ME/CFS. Many medical schools (64% of respondents) acknowledge the need to update ME/CFS education by expressing an appetite for further educational materials. The General Medical Council (GMC) and Medical Schools Council (MSC) are called upon to use their considerable influence to bring about the appropriate changes to medical school curricula so future doctors can recognise, diagnose and treat ME/CFS. The GMC is urged to consider creating a registered specialty encompassing ME/CFS, post-viral fatigue and long Covid.
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45

Burns, Dianne, Collette Bennett, and Amanda McGough. "Chronic fatigue syndrome or myalgic encephalomyelitis." Nursing Standard 26, no. 25 (February 22, 2012): 48–56. http://dx.doi.org/10.7748/ns2012.02.26.25.48.c8950.

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46

Bell, E. J., R. A. McCartney, and M. H. Riding. "Coxsackie B Viruses and Myalgic Encephalomyelitis." Journal of the Royal Society of Medicine 81, no. 6 (June 1988): 329–31. http://dx.doi.org/10.1177/014107688808100609.

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Data collected over the past 6 years suggest that Coxsackie B viruses (CBV) play an important role in myalgic encephalomyelitis (ME). Since psychological upset is a feature of this illness, 247 patients, recently admitted to a psychiatric hospital, were tested for neutralizing antibodies to CBV. A total of 12.5% had significantly raised CBV titres compared with 4–5% of ‘well’ control groups; the percentage positive was greatest (21%) in those aged 30–39 years. During 1985 and 1986 sera from 290 adults with ME were tested using the newly developed CBV IgM ELISA test; 37% were CBV IgM positive compared with 9% of 500 ‘well’ adult controls. Forty-seven children, with ME were similarly tested during this period; 38% were positive, implying recent or active CBV infection. The combined use of this ELISA test and the virus probe techniques now available should further help to elucidate the exact role of CBV in this disabling illness.
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47

Wessely, S. "Myalgic Encephalomyelitis — A Warning: Discussion Paper." Journal of the Royal Society of Medicine 82, no. 4 (April 1989): 215–17. http://dx.doi.org/10.1177/014107688908200411.

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48

White, Peter, Maurice Murphy, Jill Moss, George Armstrong, and Sir Peter Spencer. "Chronic fatigue syndrome or myalgic encephalomyelitis." BMJ 335, no. 7617 (August 30, 2007): 411–12. http://dx.doi.org/10.1136/bmj.39316.472361.80.

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49

Hanson, Maureen R., and Ludovic Giloteaux. "The gut microbiome in Myalgic Encephalomyelitis." Biochemist 39, no. 2 (April 1, 2017): 10–13. http://dx.doi.org/10.1042/bio03902010.

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Over the last dozen years, increasingly powerful DNA sequencing methods have allowed characterization of the microbes residing on and in humans in much greater detail than ever possible before. Abnormalities present in the gut microbiome--those microbial communities residing in our intestines--have now been observed in a number of diseases. One such illness is Myalgic Encephalomyelitis (ME), also known as Chronic Fatigue Syndrome (CFS). CFS was a name coined by the US Centers for Disease Control (CDC) in 1988, and reviled by patients for the resultant trivializing of this serious illness. Recently, the US National Academy of Medicine (NAM) recommended a new name: Systemic Exertion Intolerance Disease, though this name is not yet widely used. In ME, as in other diseases, the diversity of the bacterial species in the gut microbiome is lower than in healthy individuals. Furthermore, the abundances of different bacterial residents of the gut, which influence health both favourably and negatively, differ between ME patients and healthy controls. Bacteria translocate into the blood in greater amount in ME, leading to inflammation. Dysbiosis in the gut likely contributes to symptoms in this life-limiting disease.
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50

Wakefield, Denis, Andrew Lloyd, John Dwyer, S. Zaki Salahuddin, and D. V. Ablashi. "HUMAN HERPESVIRUS 6 AND MYALGIC ENCEPHALOMYELITIS." Lancet 331, no. 8593 (May 1988): 1059. http://dx.doi.org/10.1016/s0140-6736(88)91885-5.

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