Dissertations / Theses on the topic 'Music I.C.T'
To see the other types of publications on this topic, follow the link: Music I.C.T.
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 dissertations / theses for your research on the topic 'Music I.C.T.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.
1
Silva, Israel Victor Lopes da. "Aspectos t?cnico-interpretativos no quarteto de cordas n? 2 de Guerra-Peixe." Universidade Federal do Rio Grande do Norte, 2015. http://repositorio.ufrn.br/handle/123456789/20978.
Full textAbstract:
Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2016-07-11T18:12:27Z
No. of bitstreams: 1
IsraelVictorLopesDaSilva_DISSERT.pdf: 3474996 bytes, checksum: 38a532757104280f013a42a0750f78dd (MD5)Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2016-07-19T18:11:29Z (GMT) No. of bitstreams: 1 IsraelVictorLopesDaSilva_DISSERT.pdf: 3474996 bytes, checksum: 38a532757104280f013a42a0750f78dd (MD5)
Made available in DSpace on 2016-07-19T18:11:29Z (GMT). No. of bitstreams: 1 IsraelVictorLopesDaSilva_DISSERT.pdf: 3474996 bytes, checksum: 38a532757104280f013a42a0750f78dd (MD5) Previous issue date: 2015-12-16
Aspectos t?cnico-interpretativos no Quarteto de Cordas N? 2 de Guerra-Peixe vai abordar essa obra de um compositor, considerado um dos grandes expoentes da m?sica brasileira do s?culo XX, que desenvolveu v?rias vertentes em sua carreira, como music?logo, int?rprete, compositor, arranjador de r?dio e cinema, entre outras. Nesse trabalho, procuraremos visualizar na obra em quest?o seus estilos composicionais, apontando fontes que ele tenha bebido e oferecendo os elementos que subsidiar?o escolhas t?cnico-interpretativas para os futuros int?rpretes dessa obra. Com esse fim, foi realizada umaan?lise fonogr?fica comparativa entre grava??es de importantes quartetos brasileiros, entrevistas com m?sicos de relev?ncia no cen?rio nacional e experimenta??es em ensaios e recitais, sempre fazendo uma ponte do Quartetocom outras obras do compositor. Concomitantemente, foi realizada an?lise musicogr?fica entre edi??es manuscritas pelo pr?prio compositor, culminando com uma pr?pria edi??o revista.
Technical and interpretative aspects of the String Quartet No. 2 Guerra-Peixe will approach this work of a composer who is considered one of the greatest exponents of Brazilian music of the twentieth century, who developed several strands in his career as a musicologist, performer, composer, arranger radio and cinema, among others. In this work, we will see in the work in question their compositional styles, pointing sources that he has been drinking and offering elements that will subsidize technical and interpretive choices for future interpreters. After the historical context and esthetics, we will make some brief remarks about the terms performance and interpretation, to support the objective of the work, which will be the interpretation of the work. For that purpose, a comparative analysis was performed between recording of important Brazilian quartets, interviews with relevant players on the national scene and trials in rehearsals and recitals, always making a Quartet bridge with other works by the composer. Concomitantly, it was held analysis of handwritten edits by the composer, culminating with its own revised edition.
2
Bogiages, Christina Marie. "Explorando a execu??o de t?cnicas estendidas no obo? encontradas em quatro pe?as contempor?neas." Universidade Federal do Rio Grande do Norte, 2014. http://repositorio.ufrn.br/handle/123456789/20081.
Full textAbstract:
Submitted by Automa??o e Estat?stica (sst@bczm.ufrn.br) on 2016-03-18T21:55:10Z
No. of bitstreams: 1
ChristinaMarieBogiages_DISSERT.pdf: 6037377 bytes, checksum: a84cd83b8fb5234d4404581803968c7f (MD5)Approved for entry into archive by Arlan Eloi Leite Silva (eloihistoriador@yahoo.com.br) on 2016-03-18T23:07:38Z (GMT) No. of bitstreams: 1 ChristinaMarieBogiages_DISSERT.pdf: 6037377 bytes, checksum: a84cd83b8fb5234d4404581803968c7f (MD5)
Made available in DSpace on 2016-03-18T23:07:38Z (GMT). No. of bitstreams: 1 ChristinaMarieBogiages_DISSERT.pdf: 6037377 bytes, checksum: a84cd83b8fb5234d4404581803968c7f (MD5) Previous issue date: 2014-12-04
Essa disserta??o apresenta uma investiga??o do processo evolutivo das t?cnicas estendidas do obo?, atrav?s de uma analise da literatura e de pesquisa em pr?tica. O intuito deste trabalho ? facilitar a aprendizagem dos obo?stas interessados em estudar essas t?cnicas. Al?m disso, atrav?s da experimenta??o, o aluno ? encorajada ? explorar as perguntas subsequentes sobre a est?tica do som, o conceito de gesto como elemento visual e sonoro adicional, e os processos de colabora??o e cria??o em ?tempo real?. No decorrer do trabalho, s?o discutidas a rela??o entre o instrumento (o obo?) e as t?cnicas estendidas, e duas defini??es poss?veis de t?cnicas estendidas, oferecidas por Luk Vaes (2009) e Gardner Read (1993). S?o abordados a forma e o motivo pelos quais alguns compositores t?m utilizado t?cnicas estendidas em suas obras, incluindo breves discuss?es sobre t?cnicas estendidas na composi??o em tempo real (improvisa??o), t?cnicas estendidas e recursos tecnol?gicas, gesto c?nico como t?cnica estendida e sugest?es para o m?sico querendo abordar gestos c?nicos na performance. Quatro pe?as foram analisadas: ?I Know This Room So Well? ? Lisa Bielawa (2007-9); ?Four Pieces for Oboe and Piano? ? Ernst Krenek (1966); ?In Freundschaft? ? Karlheinz Stockhausen (1978); ?Atem? ? Mauricio Kagel (1969-70) e foram investigadas as dificuldades e solu??es associadas a cada t?cnica estendida encontrada nas pe?as. As seguintes fontes sobre t?cnicas estendidas foram utilizadas como base de pesquisa: livros - Heinz Holliger?s Pro Musica Nova (1972); Gardner Read?s Compendium of Modern Instrumental Techniques (1993); Peter Veale & ClausSteffen Mahnkopf?s The Techniques of Oboe Playing (1994); e Libby Van Cleve?s Oboe Unbound: Contemporary Techniques (2004); e artigos Nora Post?s ?Monophonic sound resources for the oboe: Part I ? Timbre? (1984), ?Part II- Pitch and other techniques? (1984), and ?Multiphonics for the oboe? (1982).
This dissertation presents an investigation of the evolutionary process of extended oboe techniques, through literary analysis and practical research. The objective of this work is to provide assistance to oboists interested in learning these techniques. Additionally, this work encourages the student, through the process of experimentation, to explore the questions that may arise around the aesthetics of sound, the concept of gesture as an additional visual and aural element in music, and the collaboration and ?real-time? creation processes. Discussed within the work, are the relationship between the instrument (the oboe) and extended techniques, and two possible definitions of extended techniques, provided by Luk Vaes (2009) and Gardner Read (1993). Also explored are the how and why some composers have utilized extended techniques in their compositions, including brief discussions relating to extended techniques in real-time composition (improvisation), extended techniques and technological resources, theatrical gesture as an extended technique, and suggestions of how musicians might approach theatrical gestures in performance. Four works were visited: ?I Know This Room So Well? ? Lisa Bielawa (2007-9); ?Four Pieces for Oboe and Piano? ? Ernst Krenek (1966); ?In Freundschaft? ? Karlheinz Stockhausen (1978); ?Atem? ? Mauricio Kagel (1969-70); and an exploration of the difficulties and solutions associated with each extended technique found within these pieces, was carried out. The following founding works on extended oboe techniques were used, as a basis for research: books - Heinz Holliger?s Pro Musica Nova (1972); Gardner Read?s Compendium of Modern Instrumental Techniques (1993); Peter Veale & Claus-Steffen Mahnkopf?s The Techniques of Oboe Playing (1994); and Libby Van Cleve?s Oboe Unbound: Contemporary Techniques (2004); and articles - Nora Post?s ?Monophonic sound resources for the oboe: Part I ? Timbre? (1984), ?Part II- Pitch and other techniques? (1984), and ?Multiphonics for the oboe? (1982).
3
Lewis, Michael E. (Michael Edward) 1952. "Solo Trombone Performances at the Gewandhaus in the Nineteenth Century: a Lecture Recital, Together with Three Recitals of Selected Works of G. Jacobs, S. Sulek, E. Bloch, C. Wagenseil, W. Ross, G. Pergolesi, T. George, F. Hidas, J. Albrechtsberger and Others." Thesis, University of North Texas, 1989. https://digital.library.unt.edu/ark:/67531/metadc331410/.
Full textAbstract:
This study investigates and documents tenor/bass trombone solo performances at the Gewandhaus, Leipzig, East Germany, between 1821 and 1876. Included is the discussion of a newly discovered composition, the Concertino fur Bassposaune und Orchester, by Carl Heinrlch Meyer, which is the earliest concerto for the tenor/bass trombone. Its performance at the Gewandhaus in 1821 marked the beginning of the solo tradition for the tenor/bass trombone, and the Leipzig Gewandhaus became one of the leading centers of solo trombone performance for the next fifty years.
The study includes background information on the rise of the virtuoso soloist in nineteenth-century Germany. It specifically focuses on Friedrlch August Belcke and Carl Traugott Queisser and their performances at the Gewandhaus. All solo trombone performances at the Gewandhaus in the nineteenth century have been documented, and specific information has been provided regarding the soloists, dates of performances and repertoire performed on the concerts. The paper includes a discussion of performance reviews from the Allgemeine Musfkalische Zeitung.
The conclusion discusses the importance of solo trombone performance at the Gewandhaus, and the reason for its sudden decline after 1876.
4
Kulkarni, Aditya Umesh. "Approximating Deterministic Changes to Ph(t)/Ph(t)/1/c and Ph(t)/M(t)/s/c Queueing Models." Thesis, Virginia Tech, 2012. http://hdl.handle.net/10919/33460.
Full textAbstract:
A deterministic change to a time-varying queueing model is described as either changing the number of entities, the queue capacity, or the number of servers in the system at selected times. We use a surrogate distribution for N(t), the number of entities in the system at time t, to approximate deterministic changes to the Ph(t)/Ph(t)/1/c and the Ph(t)/M(t)/s/c queueing models. We develop a solution technique to minimize the number of state probabilities to be approximated.Master of Science
5
Luyten, Marcel Andre. "Zur Synthese von (c,c,c,t)-[5.5.5.5]Fenestran /." [S.l : s.n.], 1985. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.
Full text
6
Coleman, Cal. "M Y T H I C." Digital Commons at Loyola Marymount University and Loyola Law School, 2021. https://digitalcommons.lmu.edu/etd/990.
Full textAbstract:
Mythic is an animated family series that will collide the worlds of the beloved Disney style musical feature, with everyday children’s programming. Based on 8 public domain works by Hans Christian Andersen, the series will follow Princess Viv, Farmhand Penelope, Pit-Pocket Leina, and a hopelessly romantic Prince Agner, as they travel through magical kingdoms in hopes of retrieving 8 mythical relics. Together, the four will learn about the meaning of love, the danger of greed, and the joy of being selfless as they fight to keep Leina from becoming a true villain.
7
Sclover, Nathalie. "Le marché O. T. C. Français." Paris 5, 1988. http://www.theses.fr/1988PA05P174.
Full text
8
Rueda, Javier Eduardo. "The Ph(t)/Ph(t)/s/c Queueing Model and Approximation." Thesis, Virginia Tech, 2003. http://hdl.handle.net/10919/9637.
Full textAbstract:
Time-dependent queueing models are important since most of real-life problems are time-dependent. We develop a numerical approximation algorithm for the mean, variance and higher-order moments of the number of entities in the system at time t for the Ph(t)/Ph(t)/s/c queueing model. This model can be thought as a reparameterization to the G(t)/GI(t)/s. Our approach is to partition the state space into known and identifiable structures, such as the M(t)/M(t)/s/c or M(t)/M(t)/1 queueing models. We then use the Polya-Eggenberger distribution to approximate certain unknown probabilities via a two-moment matching algorithm. We describe the necessary steps to validate the approximation and measure the accuracy of the model.Master of Science
9
Miserandino-Gaherty, Cathryn J. "The rastrology of English music manuscripts, c. 1575-c. 1642." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.670220.
Full text
10
Benfield, Judith. "Music in Verona, c.1480-1530." Thesis, University of Cambridge, 1986. https://www.repository.cam.ac.uk/handle/1810/250888.
Full text
11
Winkler, Kristin. "Aspekte mehrkriterieller Optimierung C(T)-wertiger Abbildungen." [S.l. : s.n.], 2003. http://deposit.ddb.de/cgi-bin/dokserv?idn=969923899.
Full text
12
Poul, Radek. "Analýza alternací vlny T v jazyce C." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2008. http://www.nusl.cz/ntk/nusl-217172.
Full textAbstract:
The thesis deals with detection of T-wave alternans. The presence of T-wave in surface ECG is recognized as a marker of electrical instability of heart in stage his repolarization, arise increased risk of emergence ventricular fibrillation and sudden cardiac death. The goal of our project is familiarize with methods of detection T-wave alternans. In particular spectral method and spectral method which was realized in variant for running reading values in time (“sliding window”). To suggest a QRS complex detector, localize the T-wave and to make TWA detection using spectral method and modified spectral method. This project is to be made in C language in appropriate user interface.
13
Lang, Frederick David. "The Anglican organist in Victorian and Edwardian England (c.1800 - c.1910)." Thesis, University of Hull, 2004. http://hydra.hull.ac.uk/resources/hull:5589.
Full text
14
Hoare, Matthew. "T-lymphocyte senescence and hepatitis C virus infection." Thesis, University of Cambridge, 2010. https://www.repository.cam.ac.uk/handle/1810/226746.
Full textAbstract:
Hepatitis C virus (HCV) infection is a leading cause of cirrhosis and hepatocellular carcinoma. The degree of fibrosis progression and treatment-related outcomes are critically dependent on the age of the infected individual. Progressive ageing is associated with a decline in the efficacy of adaptive immune system function. T-lymphocytes from aged subjects demonstrate multiple phenotypic and functional changes, including telomere shortening. Short telomeres are associated with poor proliferative capacity, pro-inflammatory responses and increased mortality in clinical studies. This research aimed to study telomere length changes in T-lymphocytes in chronic HCV infection and its relationship to clinical endpoints. Further, the intracellular signalling changes in T-lymphocytes with short telomeres were studied in subjects with chronic HCV. Short CD4+ T-lymphocyte telomeres were associated with the presence of severe hepatic fibrosis independent of other known factors. Telomere length was associated with blood markers of hepatic damage and dysfunction as well as histological markers of inflammation and fibrosis. Further, on prospective follow-up, short CD4+ telomere length at enrolment predicted progression to clinical endpoints of hepatic decompensation, development of hepatocellular carcinoma and death. Short CD4+ telomere length predicted a failure to respond to anti-viral treatment for HCV infection. Unexpectedly, subjects with non-viraemic HCV had short CD8+ telomere length. Liver biopsy tissue from a cohort of subjects with non-viraemic HCV was studied and demonstrated significant inflammation or fibrosis in most. To study the IFN-α signalling pathway in cells with short telomeres, I utilised the phospho-histone γ-H2AX, a downstream signal from short telomeres. CD8+ T-lymphocytes expressing γ-H2AX had the form and function of cells with end-stage differentiation. γ-H2AX+ cells had a pro-inflammatory cytokine secretion profile with high expression of IFN-γ and low IL-2. Further γ-H2AX+ cells were unable to respond to exogenous IFN-α by phosphorylating Stat1. This failure was attributable to a post-receptor defect. T-lymphocyte telomere length changes in HCV may underpin the effect of age on clinical and treatment-related outcome. Short telomeres are associated with intracellular signalling defects which may explain the failure to respond to anti-viral therapy.
15
Amin, Sharifzadeh Mohammad H. "Vertices and vortices in high-T¦c superconductors." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape9/PQDD_0020/NQ46309.pdf.
Full text
16
Cranmer, John Leonard. "Concert life and the music trade in Edinburgh c. 1780-c.1830." Thesis, University of Edinburgh, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.508785.
Full text
17
Grimshaw, Julian Roscoe. "Imitative counterpoint in English music, c.1500-1575." Thesis, University of Oxford, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.365451.
Full text
18
Colton, Lisa Marie. "Music and sanctity in England, c1260-c.1400." Thesis, University of York, 2003. http://etheses.whiterose.ac.uk/9839/.
Full text
19
Johnson, Kevin William. "A[gamma] measurement for ¹³C([pi]⁺/⁻, [pi]⁺/⁻)¹³C* at T[subscript pi]=162 MeV /." Digital version accessible at:, 1998. http://wwwlib.umi.com/cr/utexas/main.
Full text
20
Argent-Katwala, Mary Joan Grace. "The role of c Myb during T cell activation." Thesis, Institute of Cancer Research (University Of London), 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.289866.
Full text
21
Tupayachi, Serrano Erika Pamela. "C. M. T. I. Centro Médico de Terapia Integral." Bachelor's thesis, Universidad Peruana de Ciencias Aplicadas (UPC), 2019. http://hdl.handle.net/10757/625783.
Full textAbstract:
La presente investigación propone, con su planteamiento crítico, una tipología arquitectónica con énfasis en la luz natural para un centro de terapia no convencional en el distrito de Pachacámac, Lima-Perú. En esa línea, se procura mostrar cómo por medio del diseño arquitectónico y el trabajo con la luz natural se podría llegar a complementar, enriquecer y potenciar, con un enfoque preventivo, las experiencias de los pacientes que llevan a cabo tratamientos médicos orientados desde las terapias tradicionales, de enfoque reactivo. La tesis consta de seis capítulos. El primero introduce los presupuestos básicos para comprender la problemática que sirve de base a nuestros objetivos, así como los alcances y las limitaciones de la presente investigación. El segundo capítulo desarrolla el marco teórico-referencial y abunda sobre las diferencias entre la medicina tradicional, centrada en la enfermedad, y la medicina integral, centrada en la persona, aproximándose críticamente a sus ventajas y desventajas mediante el empleo de términos no arquitectónicos. El capítulo tercero describe el marco conceptual arquitectónico teniendo a la vista algunos proyectos referenciales. En los capítulos cuarto y quinto se trata sobre las características del lugar y el perfil del usuario: ambos capítulos aportan elementos críticos para elaborar, en el capítulo sexto, el programa arquitectónico. En suma, se plantea un Centro Médico de Terapia Integral ubicado en Pachacámac, que cuente con todos los beneficios de diseño tipológico analizado y descrito y que, por consiguiente, incorpore como elemento fundamental, ineludible, el aspecto emocional-sensitivo de la persona humana en la implementación del tratamiento clínico.This research proposes, with its critical approach, an architectural typology with an emphasis on natural light for an unconventional therapy center in the district of Pachacámac, Lima-Peru. In this line, we try to show how, through architectural design and work with natural light, we could complement, enrich and enhance, with a preventive approach, the experiences of patients who carry out medical treatments guided by traditional therapies, with a reactive approach. In this line, this thesis consists of six chapters. The first introduces the basic assumptions to understand the problem that serves as the basis for our objectives, as well as the scope and limitations of this research. The second chapter develops the theoretical-referential framework and abounds on the differences between traditional medicine, focused on the disease, and holistic medicine, focused on the person, critically approaching its advantages and disadvantages through the use of non-architectural terms. The third chapter describes the architectural conceptual framework with some referential projects in view. The fourth and fifth chapters deal with the characteristics of the place and the profile of the user: both chapters provide critical elements to elaborate, in the sixth chapter, the architectural program with seven functional modules for a total area constructed of 5,536 m2. In short, a Medical Center of Integral Therapy is located in Pachacámac, which has all the benefits of typological design analyzed and described and, therefore, incorporates as a fundamental element, inescapable, the emotional-sensitive aspect of the human person in the implementation of clinical treatment.
Tesis
22
Catherwood, Carolyn Paulette. "English polyphonic carol manuscripts, c. 1420-1450." Thesis, University of Oxford, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.338979.
Full text
23
Ersoy, Tunc Faik [Verfasser]. "Magnetresonanz-tomographische Merkmale der Telomerase-Reverse-Transkriptase-Promotermutationen –126 C>T und –146 C>T in primären Glioblastomen / Tunc Faik Ersoy." Bonn : Universitäts- und Landesbibliothek Bonn, 2019. http://d-nb.info/1200112520/34.
Full text
24
Maito, F?bio Luiz Dal Moro. "Ativa??o de c?lulas dendr?ticas na gera??o de c?lulas T CD8+ e T CD4+ anti-tumorais de mem?ria." Pontif?cia Universidade Cat?lica do Rio Grande do Sul, 2008. http://tede2.pucrs.br/tede2/handle/tede/5331.
Full textAbstract:
Made available in DSpace on 2015-04-14T14:50:54Z (GMT). No. of bitstreams: 1
408802.pdf: 1288333 bytes, checksum: fed9a5577936cc05fba85f19708101ee (MD5)
Previous issue date: 2008-12-18De acordo com a hip?tese da vigil?ncia imunol?gica, o sistema imune ? relevante no controle do crescimento tumoral. Entretanto, a resposta imune n?o ? capaz de barrar a progress?o de todos os tumores. Uma poss?vel explica??o para isso ? a toleriza??o das c?lulas imunes proporcionada pelo ambiente imunossupressor gerado por tumores, favorecendo seu desenvolvimento e diminuindo a efic?cia da resposta imune contra o tumor. O presente estudo visou analisar a forma??o de respostas imunes anti-tumorais in vivo, bem como identificar mecanismos capazes de reverter a toler?ncia induzida pelo tumor ? resposta imune. Para realizar este trabalho foram usados tr?s sistemas experimentais: (1) inje??o subcut?nea de tumor B16F10 para an?lise da resposta imune policlonal, (2) inje??o subcut?nea de B16OVA (OVA257-264 SIINFEKL) com transfer?ncia adotiva de c?lulas OT-I para o estudo da gera??o de resposta de c?lulas T CD8+ e (3) constru??o e inje??o subcut?nea de uma linhagem de B16F10 expressando um ant?geno restrito ao MHC classe II (B16EaRFP) com transfer?ncia adotiva de c?lulas TEa para o estudo da gera??o de resposta anti-tumoral de c?lulas T CD4+. Com estes modelos experimentais foi observada diminui??o de c?lulas no infiltrado peritumoral e da celularidade nos linfonodos drenantes (LND) ? medida que o tumor B16F10 cresce, sugerindo uma interrup??o do tr?nsito de c?lulas imunes do s?tio tumoral para o LND. A express?o de CD86 nas c?lulas dendr?ticas (DCs) nos linfonodos diminui com o crescimento tumoral. Com a eleva??o da freq??ncia precursora de c?lulas T CD8+ anti-tumorais no sistema B16OVA, o crescimento tumoral foi retardado mas n?o barrado por completo. A melhora significante da resposta contra o tumor foi obtida com a inje??o intratumoral de um ligante de TLR-4, o lipopolissacarideo de E.coli (LPS), mas apenas quando foi injetado via intratumoral, ap?s o estabelecimento do tumor in vivo. O sistema B16EaRFP revelou que a acessibilidade do ant?geno ?s c?lulas dendr?ticas ? importante na estimula??o da resposta T CD4+ anti-tumoral, resultando em maior prolifera??o de c?lulas TEa em resposta ao tumor lisado versus o tumor vivo. Quando as c?lulas tumorais foram induzidas a necrose e apoptose e injetadas subcutaneamente, houve maior porcentagem de c?lulas CD11c +YAe+ CD86+. Observou-se maior prolifera??o de c?lulas TEa nos linfonodos drenantes no grupo de camundongos injetados com c?lulas tumorais mortas por necrose, com um pico nove dias ap?s a inje??o tumoral, mas j? apresentando contra??o ap?s tr?s dias. A divis?o das c?lulas TEa tamb?m diminui gradualmente ao longo do tempo, sugerindo que nos tr?s casos h? apresenta??o limitada de ant?geno. A diferencia??o das c?lulas TEa em fen?tipo de mem?ria foi observada nos tr?s tratamentos, com mais ?nfase nos animais que receberam tumor induzido a necrose e apoptose. Contudo, as c?lulas TEa n?o foram capazes de fornecer ajuda para interromper o crescimento tumoral quando o B16EaRED foi injetado vivo. Em conjunto, os resultados sugerem que a diminui??o da apresenta??o de ant?geno e de co-estimula??o ao longo do tempo impedem a diferencia??o das c?lulas T em c?lulas de mem?ria eficazes. Os resultados indicam que o tumor intacto n?o fornece sinais suficientes para a gera??o de c?lulas T de mem?ria anti-tumoral para impedir o crescimento tumoral. Ao contr?rio, o tumor parece gerar um ambiente que n?o favorece a resposta imune, impedindo o tr?nsito de c?lulas imunes entre o LND e o sitio tumoral, diminuindo a express?o de CD86 em DCs no LND. Ainda, sinais fornecidos por c?lulas induzidas a apoptose ou necrose aumentam a apresenta??o de ant?genos tumorais e os n?veis de co-estimula??o, embora n?o substituam os sinais fornecidos pelo LPS, capazes de reverter o quadro imunossupressor
25
Perito, Carl C. "T.S. Eliot and music." Thesis, Hong Kong : Unviersity of Hong Kong, 2003. http://sunzi.lib.hku.hk/hkuto/record/B31953803.
Full text
26
Hanson, Bradley Everett William A. "T Bone Burnett, roots music, and the O Brother phenomenon." Diss., UMK access, 2005.
Find full textAbstract:
Thesis (M.M.)--Conservatory of Music. University of Missouri--Kansas City, 2005."A thesis in music history and literature." Typescript. Advisor: William Everett. Vita. Title from "catalog record" of the print edition Description based on contents viewed June 23, 2006. Includes bibliographical references (leaves 151-160). Online version of the print edition.
27
Sumner, Lott Marie. "Audience and style in nineteenth-century chamber music, c. 1830 to 1880 /." Digitized version, 2008. http://hdl.handle.net/1802/7668.
Full textAbstract:
Thesis (Ph. D)--University of Rochester, 2008.Includes abstract and vita. Includes bibliographical references. Digitized version available online via the Sibley Music Library, Eastman School of Music http://hdl.handle.net/1802/7668
28
Miroux, Céline. "Lymphocytes T régulateurs et Transplantation hépatique : modulation de l'activité des lymphocytes T régulateurs CD4+CD25+ par les drogues immunosuppressives." Phd thesis, Université du Droit et de la Santé - Lille II, 2011. http://tel.archives-ouvertes.fr/tel-00632785.
Full textAbstract:
Lorsque l'hépatite chronique C a occasionné une cirrhose et que, du fait de ses complications, le pronostic vital est en jeu au terme de quelques mois, la transplantation hépatique (TH) représente l'unique traitement efficace,. Malheureusement, la récidive quasi-systématique de la cirrhose C, après la transplantation hépatique, est la principale barrière à la survie du greffon. De nombreux facteurs ont été associés à la sévérité des récidives, et une implication des lymphocytes T régulateurs CD4+CD25+ (Treg) et de certains immunosuppresseurs a été suggérée. Par ailleurs, le patient transplanté peut également être confronté au problème du rejet aigu d'allogreffe, qui est partiellement contrôlé par les Treg et par une thérapie immunosuppressive rigoureuse. Paradoxalement, plusieurs études ont suggéré que certains immunosuppresseurs sont moins efficaces que d'autres dans la prophylaxie du rejet d'allogreffe et peuvent même être associés à des épisodes de rejet plus fréquents. Il existait donc un besoin urgent d'évaluer le rôle joué par les immunosuppresseurs sur les Treg dans la récidive de la fibrose C et dans le rejet du greffon. Dans un premier temps, nous avons confirmé l'implication des Treg dans la progression de la récidive de l'hépatite C. En effet, les marqueurs associés à cette population sont surexprimés dans le foie et dans le sérum de patients, 1 an et 5 ans après la TH, et ce proportionnellement à la sévérité de la récidive. Dans un deuxième temps, nous avons évalué l'effet d'immunosuppresseurs utilisés après la TH (cyclosporine A (CsA), tacrolimus, rapamycine et mycophénolate mofétif) sur l'activité des Treg. Nous avons ainsi montré que seule la CsA a une action inhibitrice sur l'activité des Treg, et ce, uniquement aux doses thérapeutiques de 20 et 40 ng/mL (doses administrées au long terme, 5 ans après la TH). Cette inhibition de l'activité des Treg par la CsA ne modifie pas leur phénotype (expression protéique ou génique), mais conduit à la sécrétion d'IL-2 et d'IFN-γ par les Treg, cytokines de la voie Th1. Le mécanisme immunosuppresseur de la CsA étant d'inhiber la transcription de l'IL-2, via la voie calcineurine/N-FAT, nous avons tenté d'identifier si elle agissait sur les Treg par cette voie ou par une voie indépendante de la calcineurine. Deux observations ont renforcé l'hypothèse d'un mode d'action calcineurine/N-FAT - indépendant : (i) le fait que le tacrolimus, qui a le même mécanisme immunosuppresseur que la CsA, n'inhibe pas l'activité des Treg et (ii) le fait que NIM811, un analogue de la CsA n'agissant pas sur la voie de la calcineurine, inhibe l'activité des Treg aux mêmes doses que la CsA. Cette hypothèse a par ailleurs été directement confirmée par l'absence de modification du profil de déphosphorylation du facteur de transcription N-FAT, en présence de CsA. Enfin, bien que les corticoïdes soient connus pour préserver l'activité des Treg et induisent leur prolifération in vitro, ils sont incapables de reverser l'effet inhibiteur de la CsA sur les Treg. Nos résultats suggèrent donc qu'une dose thérapeutique de CsA inhiberait l'activité des Treg CD4+CD25+. Les cellules T régulatrices jouent un rôle important dans la tolérance du greffon et dans la sévérité des récidives après la TH, leur inhibition par la CsA pourrait alors favoriser le rejet du greffon et diminuer la sévérité des récidives. Ces résultats sont importants dans la mesure où la transplantation hépatique est à l'heure actuelle la seule alternative de survie au stade du carcinome hépatocellulaire, et qu'il n'existe aucun traitement efficace contre le rejet du greffon ou la récidive de l'hépatite C. Le traitement immunosuppresseur idéal n'existe pas, cependant il ne devrait pas augmenter l'activité suppressive des Treg, au risque de favoriser la récidive de l'hépatite C, ni inhiber cette activité, au risque de favoriser le rejet du greffon.
29
Miller, Stephanie Joanne Dolskaya-Ackerly Olga. "An experiment in music romantic music aesthetics through the writings of C.S. Lewis /." Diss., UMK access, 2004.
Find full textAbstract:
Thesis (M.M.)--Conservatory of Music. University of Missouri--Kansas City, 2004."A thesis in music history and literature. Typescript. Advisor: Olga Dolskaya-Ackerly. Vita. Title from "catalog record" of the print edition Description based on contents viewed Feb. 27, 2006. Includes bibliographical references (leaves 66-68). Online version of the print edition.
30
Golby, David J. "The violin in England c.1750-c.1850 : a case-study in music education." Thesis, University of Oxford, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323864.
Full text
31
Sweetman, Lauren E. "Ng? waiata o T?ne Whakapiripiri (The music of T?ne Whakapiripiri)| Cultural expression, transformation, and healing in a M?ori forensic psychiatric unit." Thesis, New York University, 2017. http://pqdtopen.proquest.com/#viewpdf?dispub=10243485.
Full textAbstract:
In Aotearoa New Zealand, M?ori are overrepresented in criminal and mental health contexts, comprising only 14.9% of the nation, yet over 50% of institutional populations. These figures are not unique, but represent a broader struggle to overcome the legacy of colonization affecting indigenous communities worldwide. In response to these issues, I examine the impacts of M?ori cultural expression in forensic mental health through an ethnography of the kapa haka r?p? (group) in the Kaupapa M?ori forensic psychaitric unit, Te Papak?inga O T?ne Whakapiripiri. This unit reconceptualizes Western frameworks for mental health service provision, incorporating cultural education as an integral aspect of treatment, such as M?ori performing arts (i.e., kapa haka). The unit also imbues M?ori cultural values, practices, and forms of expression into daily life, an act that transforms the experience of institutionalization for t?ngata whai i te ora (patients) and the practice of forensic mental health more broadly. In this dissertation, I first unpack the collaborative methodology developed in this research, providing a set of recommendations for a more ?codetermined? research process. I then explain the research?s broader academic and social contexts, tracing the history of M?ori music scholarship, and then the history of New Zealand?s cultural and political transformation from 1840 to the present. This culminates in an ethnography of T?ne Whakapiripiri, where I examine the impacts of the kapa haka program and the unit?s broader musical activities on t?ngata whai i te ora and the clinical environment in four domains: te taha wairua (the spirit), te taha hinengaro (the mind), te taha tinana (the body), and te taha wh?nau (the community). Overall, this research illustrates that embedding forms of cultural expression such as kapa haka into the clinical model positively impacts t?ngata whai i te ora, improving their understanding and experiences of themselves, their illnesses, and their environment. Such cultural expression also shows how a Kaupapa M?ori framework transforms the institutional environment from a Western model emphasizing individualism, hierarchy, and isolation toward a more holistic, collective, and wh?nau-centered model that holds the potential to shift our understanding of what forensic mental health is and can be.
32
Fleming, Michael. "Viol-making in England, c.1580-1660." Thesis, Open University, 2001. http://eprints.hud.ac.uk/30793/.
Full textAbstract:
Viols made in England c.1580-1660 held a leading reputation, yet few survive and little is known about their makers. This study describes a new protocol for gathering information from such instruments. Images of thirty-eight viols, and data collected from them by applying the protocol, are discussed, showing that antique viols provide unreliable evidence about their original state. On top of the effects of wear, damage and alteration, changes in the structural wood of viols over time mean they cannot retain their precise original shape or dimensions. These viols, therefore, are not amenable to the sort of geometric-proportional analysis of shape which is widely considered to describe their makers’ intentions. It is also shown to be highly unlikely that either viol-makers or their clients would have mathematically-sophisticated predilections or capabilities, so such techniques would not be employed. Images of viols in a range of media are shown to give an unreliable record of the viols that were played in England, and to provide good evidence of the shapes and decoration that were familiar to those who made and used viols. The commercial organisation of viol-making is examined, demonstrating that although apprenticeship was important, it was not essential for instrument-making. Viols are shown to have been made in other places besides London, and by non-specialist woodworkers, typically described as joiners. Viol-makers are investigated by replacing conventional ideas of ‘schools’ of making with a detailed consideration of makers’ place in society. The five viol-makers praised by Thomas Mace (1676) are discussed in detail along with others, some of whom are identified for the first time. This characterisation of viol-makers and consideration of extant instruments suggests reforms for our understanding of the nature of viol-making, and calls into question traditional attributions of viols to particular makers.
33
Miles, Natasha Frances. "Approaches to accompaniment on the Baroque guitar, c.1590-c.1730." Thesis, University of Birmingham, 2014. http://etheses.bham.ac.uk//id/eprint/5149/.
Full textAbstract:
The five-course guitar was used as an instrument of accompaniment from the mid-sixteenth to the late-eighteenth century, yet its importance in this role has largely been overlooked in scholarship to date. While there are some isolated studies of individual sources, this is the first comprehensive study of the substantial body of extant guidelines with a view to understanding the styles of accompaniment on the instrument and how their practices developed during this period. This thesis documents the chronological development of the performance practices in such a way that parallels may be drawn between these sources and treatises for other instruments of accompaniment. Guitar accompaniments were, however, also strongly influenced by the performance practices associated with alfabeto chord symbols. Thus, to enable an understanding of the more idiomatic characteristics of guitar accompaniment stemming from alfabeto practices, a detailed evaluation of the true sophistication of the language of alfabeto is provided for the first time. This study provides a complete re-evaluation of the five-course guitar as an instrument of accompaniment; it challenges the past relegation of the instrument to ‘light’ or ‘frivolous’ musical repertoires; and it highlights the various approaches that were adopted in diverse performance contexts.
34
Brookes, Virginia Sheila. "The sources of British keyboard music to c 1660." Thesis, University of London, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.267092.
Full text
35
Hauge, Peter. "English music theory c.1590-c.1690 : the modal systems, changing concepts, and the development of new classification systems." Thesis, City University London, 1997. http://openaccess.city.ac.uk/8383/.
Full textAbstract:
The thesis examines the modal classification systems and the changes which lead to the development of new systems during the period c.1590 to c.1690 with particular reference to English music theory. It consists of three parts the first of which considers the English writings on music, their readership, their sources, and the basic ideas for the understanding of the traditional Gamut, solmisation system and hexachordal theory. PART 2 examines the methods employed by theorists wishing to categorise music either according to the 8-mode system or the 12-mode system. By studying Italian and German sources referred to in English writings on music, it is seen that the English theorists deal with the modal classification systems in a similar way. Furthermore, the differences between Morley's popular tract (1597), adhering to the 12-mode system, and Dowland's translation (1609) of the small tract by Ornithoparchus, promoting the 8-mode system, are also discussed. PART 3 begins by tracing the development of a new interpretation and definition of the octave as a circular principle. This leads to the theoretical recognition of the invertibility of intervals. In England, in particular the growing circle of natural philosophers and the Royal Society of London seem to play an important role by asking inquisitive questions. Seeing the octave as a circle (and hence also the Gamut), together with a stronger emphasis on the bass as the fundamental part of a composition, encouraged a new interpretation of triads and inversions. The increasing use of fixed pitches versus relative pitches also influenced the interpretation of transposition. The distinctions essential for a modal classification disappeared because of many of these new concepts. Because of the irregularities of the traditional 8-mode system and the determination to adapt it more closely to musical practice, new 8-mode systems were proposed. However, simpler classification systems were also employed as can be seen in many indices in MSS. These systems indicate the final note either together with the transpositional system (i.e. cantus mollis or durus) or with the third above (major or minor). Albeit the invertibility of intervals was acknowledged in the beginning of the seventeenth century, theorists still adhered to the concept of the senario, strongly promoted by Zarlino (1558). The senario argument led to the pairing of major imperfect consonances in opposition to minor imperfect consonances (i.e. two scale types), thus suggesting that the invertibility of intervals was not recognised. The argument was still used by English theorists and natural philosophers at the end of the seventeenth century. However, the two scales were now not only distinguished by the imperfect consonances but also by whether the seventh degree of the scale was major or minor. Thus the theoretical recognition of the major and minor keys was established.
36
Seetharamakrishnan, Devasenapathi P. 1970. "C@t : a language for programming massively distributed embedded systems." Thesis, Massachusetts Institute of Technology, 2002. http://hdl.handle.net/1721.1/62372.
Full textAbstract:
Thesis (S.M.)--Massachusetts Institute of Technology, School of Architecture and Planning, Program in Media Arts and Sciences, 2002.Includes bibliographical references (p. 67-69).
This thesis presents c@t, a language for programming distributed embedded systems that are composed of thousands (even millions) of interacting computing devices. Due to the improvements in fabricating technologies, it is becoming possible to build tiny single-chip devices equipped with logic circuits, sensors, actuators and communication components. A large number of these devices can be networked together to build Massively Distributed Embedded Systems (MDES). A wide variety of embedded control applications are envisioned for MDES: responsive environments, smart buildings, wildlife monitoring, precision agriculture, inventory tracking, etc. These examples are compelling, however, developing applications for MDES remains complex due to the following issues: MDES consist of large number of resource constrained devices and the number of potential interactions between them can be combinatorially explosive. Systems with the combined issues of such scale complexity, interaction complexity and resource constraints are unprecedented and cannot be programmed using conventional technologies. Accordingly, this thesis presents cut, a language that employs the following techniques to address the issues of MDES: 1. To address the scale complexity, c@t provides tools for programming the system as a unit. 2. c@t offers a declarative style network programming interface so that network interactions can be implemented without writing any low-level networking code. 3. The applications developed using c@t are vertically integrated. That is, the compiler customizes the runtime environment to the suit the application needs. Using this integrated approach, efficient applications can be developed to fit the available resources. This thesis describes the design, features and implementation of c@t in detail. A sample application developed using c@t is also presented.
y Devasenapathi P. Seetharamakrishnan.
S.M.
37
Norris, Rebecca L. (Rebecca Lynn) 1977. "Acquisition of the T and C system in clausal complements." Thesis, Massachusetts Institute of Technology, 2003. http://hdl.handle.net/1721.1/28344.
Full textAbstract:
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Linguistics and Philosophy, February 2004.Includes bibliographical references (leaf 48).
In order to discover how children acquire the T(ense) and C(omplementizer) system, finite and nonfinite embedded clauses produced by children in the CHILDES database were studied. It was discovered that young children often delete to in nonfinite embedded clauses, and that they use that in the C position of finite imbedded clauses far less often than adults do. By adapting Wexler's (1998) theory of optional infinitives to a Pesetsky and Torrego (2001, 2002) framework, I show that the facts about both finite and nonfinite embedded clauses are due to three conflicting constraints: a modified Unique Checking Constraint based on that in Wexler (1998), a conceptual constraint requiring both T and C to appear in every full clause, and a constraint which tells children to use phonological closeness to decide which goal to move when two goals are equally close to a probe. Children cannot avoid violation of at least one constraint, so they are required to violate as few as possible. This results in different possible derivations, each one of which produces results which are seen in child speech.
by Rebecca L. Norris.
S.M.
38
Costa, Grace Soares. "Difusão de C&T: desafios de uma comunicação integradora." Universidade Federal do Amazonas, 2009. http://tede.ufam.edu.br/handle/tede/2262.
Full textAbstract:
Made available in DSpace on 2015-04-11T13:40:39Z (GMT). No. of bitstreams: 1
grace.pdf: 1296206 bytes, checksum: 09ed183871c1bd23e84590c105b07ba1 (MD5)
Previous issue date: 2009-03-06The scientific information is a requirement in many ways. Learn what is happening is a right and a gradual awakening of the conquest of power - be informed of and fully responsible. This work aims to, through quantitative analysis, identify all the scientific events held in the state, between 2003 and 2008, and known scientific journals related to the Graduate Programs of educational institutions and local search, with the objectives of : analyzing the participation of researchers ahead of events, from the possibility of state and federal funding for this and identify the educational institutions and most active research areas and the poor, raise and analyze the major magazines aimed at dissemination of science and technology within the academic and scientific environment.
A divulgação científica é uma exigência sob vários aspectos. Saber o que está acontecendo é um direito e um despertar gradativo sobre a conquista desse poder ser informado de forma plena e responsável. Este trabalho propõe-se, por meio de análise quantitativa, identificar todos os eventos científicos realizados no Estado, entre 2003 e 2008, e conhecer as Revistas Científicas vinculadas aos Programas de Pós-Graduação das Instituições de Ensino e Pesquisa (IEPs) locais, com os objetivos de: analisar a participação dos pesquisadores frente à organização de eventos, a partir da possibilidade de financiamento estadual e federal para esse fim e identificar quais as IEPs mais atuantes e as áreas mais carentes; levantar e analisar as principais Revistas voltadas para a difusão de C&T dentro do ambiente acadêmico e científico.
39
Zajíc, Josef. "Plynofikace uhelného kotle 210 t/h; 13,63 MPa; 540 °C." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2013. http://www.nusl.cz/ntk/nusl-230871.
Full textAbstract:
This thesis aims to gas installation of the coal boiler and its thermal recount. In the first part, there is implemented calculation of the combusting chamber. After that follows the recalculation of heat exchange surfaces and proposal tube air heater, which will replace the existing air heater Ljungström. The emphasis is placed on the preservation of the exsiting steam parametrs and keeps emission limit of NOx.
40
Hanson, Frank E. III. "Trumpet Timbre: A Comparative Investigation of the Tone Quality of Two Professional C Trumpets." The Ohio State University, 1988. http://rave.ohiolink.edu/etdc/view?acc_num=osu1391686077.
Full text
41
Costa, Priscilla Ramos. "Avaliação do perfil de ativação de células T nas fases recente e estabelecida de infecções por subtipos C e não C do vírus HIV-1." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/5/5146/tde-11052017-161346/.
Full textAbstract:
A pandemia Hiv/ Aids já resultou em mais de 34 milhões de pessoas infectadas pelo vírus no mundo até o momento. Causada pelo HIV, de caráter crônico que evolui para um quadro clínico de imunodeficiência (Aids), pode tornar o indivíduo susceptível a infecções oportunistas potencialmente letais. Diferentes fatores foram identificados por ativar o sistema imune, incluindo genótipos do hospedeiro (HLAB-27, HLA-B57, CCR5delta32), co-infecções (GBV-C) e alguns fatores virais como a capacidade de replicação (fitness) e tropismo celular. O HIV-1 possui diversidade genética extensa e dinâmica. Considerando a variabilidade genética dentro do cenário da epidemia no Brasil, as clades do HIV-1 predominantes são B, F e C, além de formas recombinantes. Contudo, ainda não foi completamente estabelecido se essa diversidade genética possa influenciar o curso clínico da doença. O objetivo deste trabalho foi avaliar o perfil de ativação celular induzido encontrado em indivíduos infectados por subtipos virais C e Não- C do HIV-1, durante o primeiro ano de infecção (analisando as fases recente e estabelecida). A análise comparativa dos dois grupos (subtipos C vs. Não-C), identificou no grupo do subtipo-C uma maior frequência de células T CD4+ totais ativadas, como também uma maior frequência e ativação nas subpopulações de células T CD4+ de memória, principalmente memória efetora e efetora terminal, na fase estabelecida. Em relação às células T CD8+, deparamos na fase estabelecida com uma maior frequência de células T CD8+ de memória efetora e ativação das mesmas no grupo do subtipo-C em relação ao grupo do subtipo Não-C. Investigamos também a presença de células T CD4+ que se diferenciaram em células T reguladoras, e foi encontrada uma frequência diminuída dessas células no grupo do subtipo C em relação ao Não- C tanto na fase recente como na fase estabelecida. Na análise comparativa das fases recente e estabelecida, o grupo do subtipo Não-C apresentou um declínio tanto na quantidade de células T CD4+ como na frequência de células T CD8+ ativadas após um ano de infecção. Com base nos resultados encontrados, os dois grupos apresentaram perfis de ativação e diferenciação celular diferentes no primeiro ano de infecção pelo HIV-1, o que aponta para diferentes histórias naturais quando comparamos infecção por clades virais distintasThe Hiv/ Aids pandemic has affected more than 34 million people worldwide, reaching men, women and children. Caused by the HIV virus, a chronic infection that develops into a clinical picture of immunodeficiency (Aids), it can make the individual susceptible to opportunistic infections and result in death. Different factors were identified by activating the immune system, including host genotypes (HLAB-27, HLA-B57, CCR5delta32), co-infections (GBV-C) and some viral factors such as fitness and cellular tropism. The HIV-1 presents an extensive and dynamic genetic diversity, favoring the production of variants with molecular differences. Considering the genetic variability within the scenario of the epidemic in Brazil, the predominant subtypes of HIV-1 are B, F and C. However, it has not yet been completely established if this genetic diversity can impact the clinical course of the disease. The objective of this study was to evaluate the induced cellular activation profile found in HIV-1 C and non-C viral subtypes groups in the first year of infection (analyzing the recent and established phases). The comparative analysis of the two groups (subtypes C vs. Non-C) identified a higher frequency of activated CD4+ T cells in the C-subtype group, as well as a higher frequency and activation in CD4+ T-cell subsets of memory, mainly effector memory and terminal effector on the established phase. About CD8+ T cells, we found in the established phase a higher frequency and activation in the effector memory subset in the C- subtype group compared to the non- C subtype group. We also investigated the presence of CD4+ T cells differentiated into regulators T cells, and a decreased frequency of these cells was found in the subtype C group over non- C in both the recent and established phases. In the recent and established phase comparative analysis evidenced that the non-C subtype group presented a decline in both the number of CD4+ T cells and the CD8+ T-cell activated frequency after 1 year of infection, however, it presented a positive correlation between the viral load and frequency of activated CD4+ and CD8+ T cells in both phases. Based on the results found, the two groups presented different activation and differentiation profiles in the first year of HIV-1 infection, which points to different natural histories when comparing infection with different viral clades
42
Freitag-Sweeley, Sandra. "The F/C family of saxophones its history, future and literature /." Cincinnati, Ohio : University of Cincinnati, 2005. http://www.ohiolink.edu/etd/view.cgi?acc%5Fnum=ucin1121711234.
Full text
43
Harrod, Neal A. "You are [T]HERE: Architecture and the detachable aspect." University of Cincinnati / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1277139857.
Full text
44
Giret, Maria Teresa Maidana [UNIFESP]. "Infecção pelo vírus GB-C (GBV-C) em recém infectados pelo vírus da imunodeficiência humana tipo 1 (HIV-1): prevalência, incidência e modulação da ativação celular." Universidade Federal de São Paulo (UNIFESP), 2009. http://repositorio.unifesp.br/handle/11600/9671.
Full textAbstract:
Made available in DSpace on 2015-07-22T20:50:16Z (GMT). No. of bitstreams: 0
Previous issue date: 2009-04-29. Added 1 bitstream(s) on 2015-08-11T03:25:40Z : No. of bitstreams: 1
Publico-062a.pdf: 992519 bytes, checksum: 41750ff4e6e38ad6517d6c7541049844 (MD5). Added 1 bitstream(s) on 2015-08-11T03:25:40Z : No. of bitstreams: 2
Publico-062a.pdf: 992519 bytes, checksum: 41750ff4e6e38ad6517d6c7541049844 (MD5)
Publico-062b.pdf: 1669897 bytes, checksum: 5ca81b8b1f9a75f45902de9ce4bc36f7 (MD5)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
O GB vírus C (GBV-C) está constituído por uma fita única de RNA de polaridade positiva e pertence à família Flaviviridae. Possui uma seqüência e organização genómica parecida ao vírus da hepatite C, (HCV). A infecção pelo GBV-C não foi associada a nenhuma patologia, embora, na co infecção com o HIV, tenha sido associada a uma sobrevida maior e retardo no desenvolvimento da imunodeficiência. O efeito benéfico do GBV-C parece ser mediado por alterações na resposta imune celular; contudo, os possíveis mecanismos para explicar esse efeito ainda não foram esclarecidos. Neste trabalho investigamos a freqüência e características genotípicas assim como o impacto da infecção pelo GBV-C nos indivíduos infectados pelo HIV-1. No primeiro manuscrito examinamos os conhecimentos descritos na literatura referentes à coinfecção e propusemos algumas hipóteses para explicar esses efeitos. Posteriormente, descrevemos a taxa de infecção, a prevalência, incidência e características genotípicas do GBV-C nesta população. Assim, uma considerável freqüência de infecção pelo GBV-C foi observada e a análise filogenética dos isolados de GBV-C mostraram ser do genótipo 1 e 2. Foi observada também uma correlação inversa entre a carga viral do GBV-C e a carga viral do HIV na inclusão e um ano depois, assim como uma correlação positiva, mas não significativa, entre a carga viral do GBV-C e a contagem de linfócitos T CD4+. Finalmente, avaliamos o efeito da viremia pelo GBV-C na ativação celular em recém infectados pelo HIV-1. Os pacientes foram agrupados em GBV-C viremicos e não virémicos e foram avaliados para a contagem de linfócitos T, marcadores de ativação celular e carga viral do GBV-C e HIV-1. Foram realizadas análises de univariada e multivariada para identificar variáveis associadas com ativação celular. Demonstramos que a viremia pelo GBV-C foi correlacionada com uma diminuição da ativação celular nos indivíduos HIV positivos e este efeito mostrou se independente da carga viral do HIV. Assim, esta associação entre a replicação do GBV-C e menor ativação celular pode explicar, pelo menos em parte, a proteção conferida pelo GBV-C na progressão da doença nos indivíduos infectados pelo HIV-1.
GB virus C (GBV-C) is a single stranded positive sense RNA virus, which is a member of the Flaviviridae. It has a close sequence homology and genomic organization to hepatitis C virus (HCV). No disease has been associated with GBV-C infection but coinfection with human immunodeficiency virus (HIV) leads to improved morbidity and mortality for the HIV infected subjects. The mechanism of the beneficial effect of GBV-C appears to be mediated by alterations in the cellular immune response. In this study we investigated the frequency and genotyping characteristics as well as the impact of the GBV-C infection among recently HIV-1 infected individuals. In the first manuscript we examined the current knowledge concerning this co-infection and developed hypotheses to explain its effects. Subsequently, we described the rate of infection, the prevalence, incidence and genotypic GBV-C characteristics in this population. In that regard, a considerable frequency of GBV-C infection was observed and the phylogenetic analysis of the GBVC isolates revealed the predominance of genotypes 1 and 2. Also, it was observed an inverse correlation between GBV-C load and HIV-1 load at the enrollment and after one year of follow-up, and a positive, but not statistically significant, correlation between GBV-C load and CD4+ T lymphocyte counts. Finally, we have investigated the effect of GBV-C viremia on T cell activation in early HIV-1-infection. The volunteers were enrolled into two groups: GBV-C viremic and non viremic, all co-infected with HIV-1. They were evaluated for T cell counts, cellular activation markers, GBV-C RNA detection, and HIV-1 viral load. Non-parametric univariate and multivariate analyses were carried out to identify the variables associated with cellular activation. We demonstrated that the GBV-C viremia is correlated with a lower T cell activation in HIV-1-infected individuals and this effect was independent of HIV-1 viral load. The association between GBV-C replication and lower T-cell activation may explain, at least in part, the protection conferred by this virus against disease progression to immunodeficiency in HIV-1-infected patients.
TEDE
BV UNIFESP: Teses e dissertações
45
Conto, Emily de. "Avaliação da frequência de polimorfismos dos genes GDF-9 (c.398-39C>G, c.436C>T, c.447C>T, c.546G>A, c.557C>A e c.646G>A), AMH (p.Ile49Ser) E AMHR2 (–482A>G) em mulheres inférteis com endometriose." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2013. http://hdl.handle.net/10183/97170.
Full text
46
Thaxton, Amber E. "The scarlet "C" media portrayal of the Christian music industry /." Morgantown, W. Va. : [West Virginia University Libraries], 2003. http://etd.wvu.edu/templates/showETD.cfm?recnum=3246.
Full text
47
Jenkins, Kyle Joseph. "S-C Complications in Nineteenth-Century Sonata Movements." Diss., The University of Arizona, 2014. http://hdl.handle.net/10150/333483.
Full textAbstract:
Many have noted nineteenth-century composers' tendency to undermine crucial formal boundaries normally found in eighteenth-century sonata forms. This dissertation examines phenomena that undermine the demarcation between the expositional secondary theme and closing section. In this document I refer to such events as "S-C Complications." In their Elements of Sonata Theory: Norms, Types, and Deformations in the Late-Eighteenth-Century Sonata (2006), James Hepokoski and Warren Darcy argued that this point of articulation plays a much more crucial role than that of merely forming a boundary between S- and C-space. Rather, it serves as the goal for the entire expositional trajectory, a goal whose presence is felt from the very outset of the movement. The authors refer to this moment as "essential expositional closure," or EEC. In this dissertation I attempt to show what role EEC in Hepokoski and Darcy's sense plays in nineteenth-century movements featuring S-C Complications. I conclude that nineteenth-century composers were very likely aware of the EEC's genre-defining status since they consistently and systematically undermined it. Further, whereas in the late-eighteenth-century repertoire S-C complications were rarely employed, in the nineteenth century they became more normative, and thus non-deformational. In addition to discussing the phenomena's dialogic relationship with eighteenth-century norms, I also address their effect on tonal structure and formal syntax, concluding that S-C Complications frequently have the effect of expanding closure beyond the scope of one cadence. For practical reasons I have limited the scope of this study to non-concerto movements written primarily by Schubert, Mendelssohn, and Brahms.
48
Ghazal, Khaldoun. "Le rôle des cellules T régulatrices en transplantation hépatique." Thesis, Paris 6, 2014. http://www.theses.fr/2014PA066225/document.
Full textAbstract:
Les résultats de la transplantation hépatique (TH) se sont considérablement améliorés mais la survie à long terme est une préoccupation des transplanteurs. Elle dépend de la survenue d’un rejet, de la récidive de l’hépatite C, du traitement immunosuppresseur et de ses complications. Après une TH suite à une complication de l’hépatite C, l'infection du greffon par le virus de l’hépatite C (VHC) est constante, et l'évolution de l'hépatite chronique est plus rapide et agressive que chez les non transplantés. L’implication des cellules T régulatrices (Treg) a été suggérée dans l’induction de tolérance après transplantation et dans la persistance de l’infection par le VHC. Le nombre et la fonction des Treg seraient influencés par le traitement immunosuppresseur (IS). Dans ce contexte, je me suis intéressé au rôle des Treg dans l’évolution de la TH, et les effets des différents traitements utilisés (IS et anti-VHC) sur ces cellules. Les résultats montrent que les Treg, en particulier les cellules régulatrices de type 1 (Tr1), seraient prédictifs de la réponse au traitement antiviral C, et aussi que les Treg pourraient être impliquées dans l’évolution de la récidive virale C après TH. JE montre aussi que les inhibiteurs de mTor induisent une augmentation de taux des Treg chez les patients transplantés hépatiques après changement du traitement d’un anticalcineurine, et que les anticalcinurines réagissent différemment sur l’activité suppressive des Treg in vitro. En conclusion, je précise le rôle majeur des Treg à la fois dans l’évolution de la récidive virale C sur le greffon hépatique, mais également quels sont les IS qui auraient un effet favorable sur le développement des TregThe results of liver transplantation (LT) have improved significantly, but long-term graft survival is still a major concern for doctors. It depends on the rejection rates, the recurrence of hepatitis C, and the immunosuppressive treatment and its complications. After LT, the graft reinfection with HCV is constant, and the evolution of chronic hepatitis is faster and more aggressive when compared to the time course before transplantation. It has been suggested the regulatory T cells (Treg) are involved in the induction of tolerance after organ transplantation, and in the persistence of HCV infection by suppressing the HCV-specific T responses. Furthermore, the number and function of Treg are very likely influenced by the immunosuppressive therapy used after transplantation. In this context, my work focuses on the role of Treg cells in the evolution of liver transplantation, and the effects of different treatments used after LT (immunosuppressive and anti-HCV) on this population. The results of my thesis show that the Treg cells (Type-1 regulatory cells, Tr1, in particular) are predictive of the response to the anti-HCV treatment after LT, and that Treg cells are associated with severe evolution of recurrent hepatitis C. I show that mTOR inhibitors have a positive impact on the number of circulating Treg cells in patients who underwent a conversion of therapy from Tacrolimus to a mTOR inhibitor, and that calcinurine inhibitors have different effects on Treg suppressive activity in vitro. In conclusion, we bring evidences on the involvement of Treg cells in HCV recurrence and treatment failure after liver transplantation and in their interaction with immunosuppressive drugs
49
Reyes, Mandujano Ivonne Fanny. "Asociación del polimorfismo genético de las IL-1A C(889)T Y IL-1B C(+3953/4)T en un grupo de adultos con periodontitis crónica." Master's thesis, Universidad Nacional Mayor de San Marcos, 2015. https://hdl.handle.net/20.500.12672/4633.
Full textAbstract:
La periodontitis crónica es la causa más común de pérdida de dientes en el mundo y muchos factores de riesgo tales como las infecciones, la respuesta inflamatoria, la higiene oral, la edad, los hábitos de fumar y las características genéticas individuales están involucrados en el desarrollo de esta enfermedad. La identificación de los factores genéticos que condicionan la inflamación oral puede ayudarnos a comprender la predisposición a desarrollar periodontitis. Las interleuquinas, en especial la IL-1, tienen mucha importancia en la evolución de la enfermedad periodontal, debido a que son proteínas solubles que median interacciones complejas entre los linfocitos, las células inflamatorias y otros elementos celulares del tejido conectivo. Por tal motivo, el propósito de este estudio fue determinar la asociación de los polimorfismos genéticos de la IL-1A C(-889)T, IL-1B C(+3953/4)T, con la periodontitis crónica en un grupo de peruanos. Para ello se reclutaron 94 personas con periodontitis crónica y 96 personas periodontalmente sanas, a quienes se les extrajo una muestra de sangre para obtener el ADN y realizar la genotipificación de la IL-1A e IL-1B, con la técnica de PCR-RFLP. Los datos fueron analizados con el test de 2, 2de tendencia lineal y regresión logística, con un 95% de intervalo de confianza. Los resultados muestran una asociación estadísticamente significativa entre el genotipo positivo de la IL-1B y el genotipo compuesto positivo, con la periodontitis crónica. Palabras clave: Interleuquinas, Citoquinas, Periodontitis Crónica, Polimorfismo
Genético, PCR- RFLP.--- Chronic periodontitis is the most common cause of tooth loss in the world and many risk factors such as infections, inflammatory response, oral hygiene, age, smoking habits and individual genetic characteristics are involved in the development of this disease. The identification of genetic factors that influence oral inflammation may help us understand the predisposition to developing periodontitis. Interleukins, in particular IL-1, are very important in the development of periodontal disease because they are soluble proteins that mediate complex interactions among cells, inflammatory cells and other cellular elements of connective tissue. Therefore the purpose of this study was to determine the association of genetic polymorphisms of the IL-1A C (-889) T, IL-1B C (+3953/4) T, with chronic periodontitis in a group of Peruvians. For this purpose, 94 people with chronic periodontitis and 96 periodontally healthy people were recruits and blood for DNA and perform genotyping of IL-1A and IL-1B, with the PCR-RFLP was extracted to them. Data were analyzed with the test 2, 2 of linear trend and logistic regression with 95% confidence interval. The results show a statistically significant association between positive genotype of the IL-1B and the positive composite genotype with chronic periodontitis. Keywords: Interleukins, cytokines, Chronic Periodontitis, Genetic Polymorphism, PCR-RFLP.
Tesis
50
Gerber, Casey Lynn. "Ear training and music reading methods used by Philip C. Hayden : music literacy through rhythm forms /." Full text available from ProQuest UM Digital Dissertations, 2008. http://0-proquest.umi.com.umiss.lib.olemiss.edu/pqdweb?index=0&did=1850417161&SrchMode=1&sid=1&Fmt=2&VInst=PROD&VType=PQD&RQT=309&VName=PQD&TS=1279215869&clientId=22256.
Full textAbstract:
Thesis (Ph.D.)--University of Mississippi, 2008.Typescript. Vita. "May 2008." Major professor: Alan L. Spurgeon Includes bibliographical references (leaves102-113). Also available online via ProQuest to authorized users.