Journal articles on the topic 'Musculoskeletal system Diseases Physical therapy'

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1

Begidova, Tamara P., and Ekaterina Y. Mukina. "PNF-therapy in complex rehabilitation of individuals with musculoskeletal system disorders." Tambov University Review. Series: Humanities, no. 1 (2022): 165–71. http://dx.doi.org/10.20310/1810-0201-2022-27-1-165-171.

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The subject of the study is the assessment of the integrated application of rehabilitation measures with the use of PNF-therapy in disorders of the musculoskeletal system. The analysis of the available scientific and methodological literature revealed insufficient study and practical implementation of modern rehabilitation techniques for musculoskeletal system disorders of various etiologies, showing the increasing relevance of physical rehabilitation in the modern world. Rehabilitation for chronic diseases of the musculoskeletal system is a continuous process that requires constant adaptation of the methods used to the needs of the person with disabilities. Studies of the effect of PNF-therapy should include: sensorimotor control of limbs, sitting and standing, control of movement coordination, regularity of exercise and health-related quality of life. The data obtained can be used in the practice of teaching students, undergraduates, graduate students and attendees of faculties and retraining and advanced training courses in the field of “Physical education for individuals with disabilities (adaptive physical education)”, as well as instructors in adaptive physical education in the rehabilitation of people with diseases of the musculoskeletal system. Theoretical aspects related to the use of PNF-therapy in the complex rehabilitation of persons with musculoskeletal system lesions are discovered. Forecast of the probable direction of perspective physical rehabilitation development for this contingent is given.
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Davletiyarova, K. V., V. L. Soltanova, L. V. Kapilevich, and V. I. Andreyev. "Correction of disordered equilibrium function in students through exercise therapy." Bulletin of Siberian Medicine 8, no. 3 (June 28, 2009): 23–26. http://dx.doi.org/10.20538/1682-0363-2009-3-23-26.

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The method of stabilography was used to study the equilibrium function in students with vascular heart diseases and diseases of musculoskeletal system going in for exercise therapy (ET). The organization of physical training with the use exercise therapy favors the normalization of the equilibrium function and coordination abilities, and the effect is more pronounced in the group of students with diseases of the musculoskeletal system.
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3

Davletiyarova, K. V., L. V. Kapilevich, V. L. Soltanova, Ye B. Baranova, and V. I. Andreyev. "Adaptation possibilities of students going to exercise therapy." Bulletin of Siberian Medicine 10, no. 3 (June 28, 2011): 116–19. http://dx.doi.org/10.20538/1682-0363-2011-3-116-119.

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The cardiointervalography method was used to study adaptation possibilities of students with vascular heart diseases and diseases of musculoskeletal system going to exercise therapy. The physical training organization with use exercise therapy favors the adaptation and functional reserve improvement, and the effect is more in 1st year study students with vascular heart diseases.
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4

Vallati, Carlo, Antonio Virdis, Marco Gesi, Nicola Carbonaro, and Alessandro Tognetti. "ePhysio: A Wearables-Enabled Platform for the Remote Management of Musculoskeletal Diseases." Sensors 19, no. 1 (December 20, 2018): 2. http://dx.doi.org/10.3390/s19010002.

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Technology advancements in wireless communication and embedded computing are fostering their evolution from standalone elements to smart objects seamlessly integrated in the broader context of the Internet of Things. In this context, wearable sensors represent the building block for new cyber-physical social systems, which aim at improving the well-being of people by monitoring and measuring their activities and provide an immediate feedback to the users. In this paper, we introduce ePhysio, a large-scale and flexible platform for sensor-assisted physiotherapy and remote management of musculoskeletal diseases. The system leverages networking and computing tools to provide real-time and ubiquitous monitoring of patients. We propose three use cases which differ in scale and context and are characterized by different human interactions: single-user therapy, indoor group therapy, and on-field therapy. For each use case, we identify the social interactions, e.g., between the patient and the physician and between different users and the performance requirements in terms of monitoring frequency, communication, and computation. We then propose three related deployments, highlighting the technologies that can be applied in a real system. Finally, we describe a proof-of-concept implementation, which demonstrates the feasibility of the proposed solution.
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5

Bogdanov, E. I., T. G. Sakovets, and R. A. Altunbaev. "Efficiency of intra-articular, periarticular, local intramuscular and perineural injection therapy in the treatment of nociceptive and neuropathic pain syndromes." Kazan medical journal 96, no. 4 (August 15, 2015): 571–77. http://dx.doi.org/10.17750/kmj2015-571.

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Diseases of the musculoskeletal system are accompanied by nociceptive, neuropathic pain which is, in addition to kinesitherapy, physical therapy and acupuncture, widely treated using the local injection therapy. This treatment method is commonly used by physicians of different specialties for about 100 years and includes intra-articular, periarticular, perineural, intramuscular administration of different medicines, homeopathic remedies or medical devices. Hyaluronic acid salts, nonsteroid anti-inflammatory drugs, glucocorticosteroids, local anesthetics, vitamin B12, botulinum toxin A medications are often used for the treatment of degenerative conditions, posttraumatic joint disease, delayed complications of aseptic, bacterial and viral inflammatory, rheumatic processes within and out of the joints, such as: pathology of periarticular soft tissues as a consequence of local physical overload after acute injury, chronic microtrauma, sport trauma, affected facet joints and periarticular space at patients with dorsopathy, local muscle hypertonus (myofascial pain syndrome), neuropathy. The unique medication Hyalrepair-02/10 chondroreparant® based on the solid-state modificated hyaluronic acid salts and biogenic metabolites (non-drug bioorganic depot complex consisting of hyaluronic acid, amino acids and ascorbyl phosphates) is widely used at spine diseases and diseases of the musculoskeletal system, and it has showed good safety at local injection therapy. Heterogeneity of target tissues at patients with the musculoskeletal disorders, pharmacological substances as a part of injection drugs, and dosages of medicines and medical devices as well as individual patient reactions to the local therapy depending on severity of the disease, compensatory abilities and other reasons determines the necessity of carrying out a clinical comparison between different types of local injections with various groups of preparations.
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6

Voloshyn, O. I., O. V. Glubochenko, I. V. Pankiv, V. G. Glubochenko, and I. V. Prysiazhniuk. "Rheumatic manifestations of thyroid pathology. Literature review." Clinical Endocrinology and Endocrine Surgery, no. 1 (April 6, 2022): 57–67. http://dx.doi.org/10.30978/cees-2022-1-57.

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Thyroid disease can be accompanied by a variety of rheumatic manifestations, ranging from early growth defects during infancy to adult manifestations such as arthralgias, myalgias, myopathy, acropachy, arthritis, osteoporosis. Objective — to provide a summarizing current literature on the analysis of a variety of musculoskeletal disorders in hyperthyroidism and hypothyroidism and possible mechanisms that explain this connection. Materials and methods. The authors conducted a systematic literature search for relevant Englishlanguage publications published between June 2011 and October 2021 in MedLine, PubMed, and Google Scholar. A variety of rheumatic manifestations in hyperthyroidism and hypothyroidism include: arthropathy, myopathy, adhesive shoulder capsulitis, thyroid acropachy, tunnel (carpal) syndrome, Raynaud’s phenomenon, Hoffman’s syndrome, osteoporosis. Thyroid diseases commonly cause musculoskeletal complaints and may even present with rheumatic syndromes before the nature of the underlying endocrinopathy is apparent. On occasion, thyroid disorders can mimic some rheumatic diseases and leading to diagnostic errors. On the other hand, thyroid disorders can coexist with rheumatic diseases as well as rheumatic symptoms and findings. Musculoskeletal complaints can be related to unidentified and untreated thyroid diseases. However, it is important to keep in mind that the therapy for these diseases might lead to myopathies. As a result, internists, endocrinologists, and rheumatologists should be well-versed in recognizing how thyroid illnesses influence the musculoskeletal system and must be aware of these correlations to ensure that the associated condition is not missed, or the diagnosis is not delayed. This will aid in avoiding diagnostic mistakes and provide early suspicion of thyroid pathology and correct treatment. Keywords: rheumatic manifestations, hyperthyroidism, hypothyroidism, thyroid pathology, musculoskeletal syndrome.
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7

Fedorenko, S. М., M. S. Balazh, V. V. Vitomskyi, О. B. Lazarіeva, and M. V. Vitomskа. "Economic components of the morbidity and rehabilitation of the musculoskeletal system as factors of the organization of the system of physical therapy at the ambulatory stage." Health, sport, rehabilitation 6, no. 1 (June 6, 2020): 57. http://dx.doi.org/10.34142/hsr.2020.06.01.07.

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<p><strong>The aim</strong>: to consider the economic consequences of morbidity and rehabilitation of the musculoskeletal system (MSS) among the able-bodied population to confirm the economic feasibility of using physical therapy and the development of its system in the country in order to reduce losses from MSS pathologies in Ukraine.</p><p><strong>Material and methods</strong>: the data of 63 literature sources on the prevalence of MSS diseases among the working population, their economic consequences (payments for treatment, employers' losses), the role of rehabilitation, physical therapy in reducing financial costs, and the needs of the population in rehabilitation and physical therapy were analyzed.</p><p><strong>Results.</strong> Occupational diseases of the MSS are characterized by long-term disability and a high incidence of disability. The effectiveness of rehabilitation, including economic, with injuries and diseases of the MSS was given great attention in the works of domestic and foreign authors. A significant amount of research has confirmed that the funds spent on the implementation of rehabilitation are reimbursed many times by reducing the periods of temporary and permanent loss of working capacity.</p><p><strong>Conclusion.</strong> The economic feasibility of directing the funds for rehabilitation and physical therapy in pathologies of the MSS is reflected in the short duration of disability, the period of adaptation of patients to work, and the need for rehabilitation. Therefore, channeling funds into building a rehabilitation and physical therapy system in Ukraine is appropriate in the framework of medical reform and will have long-term positive economic consequences.</p>
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8

Bas, O. A., N. O. Ivasyk, O. I. Tyravska, and A. M. Hertsyk. "Analysis of physical therapy application in children with acute lymphoblastic leukemia (literature review)." Zaporozhye Medical Journal 23, no. 3 (June 7, 2021): 425–34. http://dx.doi.org/10.14739/2310-1210.2021.3.215664.

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The aim – theoretical review of the use of physical therapy in children with acute lymphoblastic leukemia. The problem of restoring the health of children with acute lymphoblastic leukemia (GLL) is due to the increased incidence of cancer, the duration of special treatment and the development of complications and comorbidities. The main complaints are fatigue, pain, muscle weakness, decreased mobility and endurance, depression, anxiety, mood swings. Pathology of the musculoskeletal system, gastrointestinal tract and endocrine system occur with equal frequency. Today, the main expected therapeutic effect in pediatric oncology should be considered not only the clinical recovery of patients, but also their return to the previous social position in the family, school and community, the restoration of physical, psychological and social health. The problem of physical therapy of children with acute lymphoblastic leukemia was studied by many scientists. According to the literature, physical exercises reduce the fatigue associated with the tumor process, improving the functional capacity of the body and increasing metabolism. There is a positive effect of exercise on muscle strength and flexibility, but there are ambiguous conclusions from different authors on the effect of exercise on cardio-respiratory function in the course of maintenance therapy in children with GLL who have cancer fatigue. Conclusions. An important area of physical therapy in oncology is the use of dosed physical activity, which, according to many researchers, increases the effectiveness of treatment. Recently, the prevailing opinion is that regular physical activity is safe and can have potential benefits for the musculoskeletal, cardiovascular, respiratory and immune systems of pediatric patients with hematological diseases.
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9

Feng, Site, Jiahao Li, Jingjing Tian, Sheng Lu, and Yu Zhao. "Application of Single-Cell and Spatial Omics in Musculoskeletal Disorder Research." International Journal of Molecular Sciences 24, no. 3 (January 23, 2023): 2271. http://dx.doi.org/10.3390/ijms24032271.

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Musculoskeletal disorders, including fractures, scoliosis, heterotopic ossification, osteoporosis, osteoarthritis, disc degeneration, and muscular injury, etc., can occur at any stage of human life. Understanding the occurrence and development mechanism of musculoskeletal disorders, as well as the changes in tissues and cells during therapy, might help us find targeted treatment methods. Single-cell techniques provide excellent tools for studying alterations at the cellular level of disorders. However, the application of these techniques in research on musculoskeletal disorders is still limited. This review summarizes the current single-cell and spatial omics used in musculoskeletal disorders. Cell isolation, experimental methods, and feasible experimental designs for single-cell studies of musculoskeletal system diseases have been reviewed based on tissue characteristics. Then, the paper summarizes the latest findings of single-cell studies in musculoskeletal disorders from three aspects: bone and ossification, joint, and muscle and tendon disorders. Recent discoveries about the cell populations involved in these diseases are highlighted. Furthermore, the therapeutic responses of musculoskeletal disorders, especially single-cell changes after the treatments of implants, stem cell therapies, and drugs are described. Finally, the application potential and future development directions of single-cell and spatial omics in research on musculoskeletal diseases are discussed.
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10

Maduakonam, Dim Edwin, Lam Ying Lee, Ho Wai Yip Kenneth, Yau Ching Hin Raymond, and WH Shek Tony. "Tuberculous osteomyelitis of the proximal femur masquerading as bone secondary: A case report." Journal of Orthopaedics, Trauma and Rehabilitation 27, no. 1 (March 24, 2020): 72–76. http://dx.doi.org/10.1177/2210491720907492.

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Tuberculosis is a mycobacterial infection, but it can mimic many diseases including diseases of the musculoskeletal system. The need to consider it as a differential diagnosis of musculoskeletal tumours and tumour-like conditions cannot be overemphasized. The opinions of some, that tuberculosis is a disease of the undeveloped world, can no longer be sustained especially in the presence of immunodeficiency disorders, including HIV/AIDS, which have a worldwide prevalence. Traditionally, literature evidence shows that tuberculosis can mimic quite a number of diseases, including cancers. This has been found to be true, even in some technologically advanced countries. We present a case of hepatocellular cancer patient incidentally found to have concomitant hepatic tuberculosis who complained of bone lesion, with clinico-radiologic features of metastasis, but which turned out to be a tuberculous infection of the bone.
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11

Czech, Szymon, Jacek Hermanson, Piotr Rodak, Tomasz Stołtny, Łukasz Rodak, Sławomir Kasperczyk, Bogdan Koczy, and Michał Mielnik. "Sports Activity Following Cementless Metaphyseal Hip Joint Arthroplasty." Journal of Human Kinetics 60, no. 1 (December 28, 2017): 225–32. http://dx.doi.org/10.1515/hukin-2017-0112.

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Abstract An adequate level of physical activity has a substantial effect on both mental and physical human health. Physical activity is largely dependent on the function of the musculoskeletal and articular system. One of the most frequent diseases of this system is degenerative joint disease. Due to the changing and more demanding lifestyles and patients’ willingness to be involved in sports activity, the expectations of hip joint arthroplasty are becoming increasingly high. Alleviating pain ceases to be the only reason for which patients choose surgical interventions, while the expectations often include involvement in various sports. Only few studies contain recommendations concerning the frequency, type and intensity of sports activity which are acceptable after hip joint arthroplasty. The aim of the study was to evaluate function and physical activity of people following cementless short-stem hip joint arthroplasty in the observation of at least five years. The study group comprised 106 patients who underwent total hip arthroplasty due to degenerative joint diseases, chosen according to inclusion criteria. Patients underwent routine physical examinations following the Harris Hip Score protocol, responded to the UCLA scale and questionnaires concerning pre-surgical and current physical activity. Our results demonstrated that hip joint arthroplasty in people suffering from degenerative joint diseases has a beneficial effect on their level of functioning and physical activity. Although physical activity and the level of functioning obviously reduced as a person aged, the level of physical activity continued to be very high in both groups, with function of the hip joint evaluated as very good.
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12

Svetlakova, M. V., and L. E. Morozova. "Hydrorehabilitation of women aged 55-60 with a diagnosis of hernia of the lumbar spine." Scientific and educational basics in physical culture and sports, no. 2 (November 21, 2021): 49–55. http://dx.doi.org/10.57006/2782-3245-2022-6-2-49-55.

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Relevance. Vertebroneurological disorders are the most common chronic diseases. Lumbar osteochondrosis is one of the most common diseases of the peripheral nervous system, has a tendency to relapses, often causing temporary disability. At the present stage of the development of medicine, physical therapy occupies a prominent place in the process of rehabilitation with diseases of the musculoskeletal system.Purpose. Improvement of the functional state of the musculoskeletal system and cardiovascular system in 55-60-year-old women with lumbar spine hernias.Methodology and organization of the research. There were 7 women under observation, aged 55-60 years with a diagnosis of "hernia of the lumbar spine", at the polyclinic stage. According to the previous examination, all patients had characteristic complaints of intermittent pain syndrome of moderate and weak intensity. There were also complaints of rapid fatigue.The results of the research. The study of the general condition of the patients by means of the Roland-Morris questionnaire indicated the existing disorders of the patients' vital activity (11.6 points). When comparing repeated results, a decrease in the level of violations to 6.3 points was reliably noted.Conclusions. Comparison of these functional samples showed reliable dynamics of the results.
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Venâncio, Raysa Silva, Tamiris Beppler Martins, Keyla Mara Dos Santos, and Gilmar Moraes Santos. "Physical Therapy at the postoperative of hip endoprosthesis for osteosarcoma: a case report." Manual Therapy, Posturology & Rehabilitation Journal 14 (December 27, 2016): 366. http://dx.doi.org/10.17784/mtprehabjournal.2016.14.366.

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Introduction: Osteosarcoma is the most common malignancy among musculoskeletal tumors. It can be treated for preservation member or amputation. The cases treated for preservation member have improved functionality and quality of life, however, patients with oncologic diseases exhibit symptoms of anxiety and depression. The aim of this study is to describe the role of physiotherapy in the hip endoprosthesis after surgery for osteosarcoma of a patient treated at the Clinic Physiotherapy School of the University of the State of Santa Catarina (CEFID / UDESC) and verify their quality of life, functionality and symptoms of anxiety and depression. Materials and Methods: A descriptive study through case report. The subject was assessed before and after 10 sessions of physiotherapy on the quality of life, functionality and symptoms of anxiety and depression using a standardized assessment form, the Quality of Life Assessment Questionnaire (WHOQOL-BREF), the system Functional assessment (Musculoskeletal Tumor Society Rating Scale - MSTS); of Lower Limb Function Scale (EFMI) and the Hospital Anxiety and Depression Scale (Hospital Anxiety and Depression Scale - HADS); Results and Conclusions: Physical therapy treatment proposed to the patient allowed the increase of muscle strength; increased muscle tropism; improved member functionality (65% of EFMI); possible reduction of anxiety or depressive symptoms in HADS; presenting score (67.31%) of the WHOQOL-BREF and (56%) in MSTS. Thus, based on the functional, emotional and psychological outcomes, the proposed physical therapy had a positive influence on a patient's quality of life osteosarcoma at the proximal end of the left femur, underwent resection and reconstruction member with endoprosthesis.
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Rickhi, Badri, Hude Quan, Sabine Moritz, Heather L. Stuart, and Julio Arboleda-Flórez. "Mental Disorders and Reasons for Using Complementary Therapy." Canadian Journal of Psychiatry 48, no. 7 (August 2003): 475–79. http://dx.doi.org/10.1177/070674370304800708.

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Objective: To compare patients with and without mental disorders who seek services from a complementary therapy practitioner with regard to quality of life, reasons for seeking complementary therapies, complaints, and physical conditions. Method: We studied new patients who attended a complementary therapy clinic offering acupuncture treatment between July 1, 1993, and March 31, 1995. We collected data from a self-administered questionnaire and from a physician-conducted psychiatric assessment. Results: Of the 826 new patients at the clinic, 578 (70%) presented with a mental disorder. Patients with a mental disorder perceived their quality of life as poorer and reported greater levels of stress than did those without a mental disorder. However, the groups did not differ in their self-reported reasons for seeking complementary therapies, in their complaints, or in their physical conditions. Among patients with a mental disorder, the major reasons for choosing complementary therapies were personal preference, interest, or belief in complementary therapies (44.3%) and perceiving complementary therapies as a last resort (30.7%). Most patients with a mental disorder saw a complementary practitioner for musculoskeletal and connective-tissue disorders (44.1%), fatigue (26.6%), and headache (15.2%). The most frequent physical illnesses among patients with a mental disorder were diseases of the musculoskeletal system and connective tissue (42.6%). Conclusion: Like their counterparts without a mental disorder, individuals with a mental disorder use complementary therapies because of personal beliefs. The wide use of complementary therapies among individuals with a mental disorder may be ascribed to a poor quality of life and high levels of distress.
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Paula, Daniela Annanias Gimenes de, Ronaldo Alves da Cunha, and Carlos Vicente Andreoli. "HEALTH PROBLEMS OF BASKETBALL REFEREES:A PROSPECTIVE STUDY." Revista Brasileira de Medicina do Esporte 27, no. 2 (June 2021): 195–200. http://dx.doi.org/10.1590/1517-8692202127022021_0128.

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ABSTRACT Introduction: Basketball referees are the authorities responsible for ensuring that rules and regulations are followed and for making decisions. The ability of referees to respond to the physical and physiological demands imposed during the game is essential for good performance on the court. Objective: To understand the context in which health problems faced by basketball referees occur and to outline the epidemiological profile of musculoskeletal injuries. Methods: A prospective cohort study was conducted in which basketball referees were evaluated using a standardized form. The participants were monitored online weekly for 12 weeks using the Oslo Sports Trauma Research Center questionnaire to assess health problems, such as diseases (affecting the respiratory, cardiovascular, digestive or neurological systems) or musculoskeletal injuries (acute or from overuse). Results: The study sample consisted of 78 referees with a mean age of 36.5 (±9.8) years. Most referees (97.4%) found it important to implement a preventive program. In relation to the health problems reported during follow-up, there was an incidence rate of 23.7 injuries per 1000 hours of play (95% CI 19.5 - 27.9) and the mean weekly prevalence of diseases was 3.2 (95% CI 0.4 – 6.0) and of injuries was 17.4 (95% CI 16.5 – 18.3). Conclusion: Through this study, it was possible to conclude that there was an incidence rate of 23.7 injuries per 1000 hours of play (95% CI 19.5 - 27.9) and a mean prevalence of diseases of 3.2 (95% CI 0.4 - 6.0) and musculoskeletal injuries of 17.4 (95% CI 16.5 - 18.3). The most common health problems that affected basketball referees were musculoskeletal overuse injuries of the lower limbs. Level of evidence I; Prospective cohort study .
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Li, Fuzhong, K. John Fisher, Peter Harmer, and Machiko Shirai. "A Simpler Eight-Form Easy Tai Chi for Elderly Adults." Journal of Aging and Physical Activity 11, no. 2 (April 2003): 206–18. http://dx.doi.org/10.1123/japa.11.2.206.

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Low-impact exercise that appeals to elderly adults and can be done almost anywhere provides both societal and individual benefits. One such program is Tai Chi, a traditional Chinese dancelike conditioning exercise. The article presents an easily adopted and adapted 8-form Tai Chi program (Easy Tai Chi) designed for older adults or individuals with mobility challenges or physical impairments. Derived from a simplified 24-form Yang-style Tai Chi, it stresses postural control and body-limb rotational movements. Easy Tai Chi can be performed either standing or sitting, depending on the physical and functional limitations of participants. Preliminary data indicate a number of health benefits of Easy Tai Chi compared with a traditional exercise program. Although subject to further empirical evaluation, Easy Tai Chi can be applied in research settings to investigate prevention or amelioration of hypokinetic diseases and in clinical settings to treat physically frail seniors or others with functional impairments of the musculoskeletal or cardiovascular system.
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Niewiadomska, Ewa, Beata Łabuz-Roszak, Piotr Pawłowski, and Agata Wypych-Ślusarska. "The Physical and Mental Well-Being of Medical Doctors in the Silesian Voivodeship." International Journal of Environmental Research and Public Health 19, no. 20 (October 17, 2022): 13410. http://dx.doi.org/10.3390/ijerph192013410.

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Physical and mental well-being are important determinants of medical doctors’ lives, including their professional activity, which has a direct impact on the health and lives of patients. The aim of the study was to assess the health condition of medical doctors from the Silesian Voivodeship. The physical health condition, including the prevalence of chronic diseases, drug therapy, and pro-health activities, was assessed. Data on mental health according to the HADS scale (hospital anxiety and depression scale) referred to the selected socio-economic and professional aspects of life, as well as life and job satisfaction. The doctors most often reported diseases of the circulatory system and diseases of endocrine system, nutritional status and metabolic changes, allergies, and degenerative changes in the musculoskeletal system and connective tissue. Chronic diseases and anxiety or depressive disorders affected doctors aged 50–80 years more frequently, and those doctors undertook preventive pro-health activities more often. The higher risks of anxiety and depression were related to their social and professional roles, lower economic status, overweight or obesity, chronic diseases, pharmacotherapy, diets, and chronic fatigue. On the other hand, frequent physical activity, a longer sleep duration, smaller weekly workload, type of rest, a higher sense of job satisfaction, and a higher level of life satisfaction reduced the risk of disorders. The health condition of medical doctors in the Silesian Voivodeship requires decisive remedial actions in the professional and non-professional spheres.
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Tenti, Sara, Pierpaolo Correale, Sara Cheleschi, Antonella Fioravanti, and Luigi Pirtoli. "Aromatase Inhibitors—Induced Musculoskeletal Disorders: Current Knowledge on Clinical and Molecular Aspects." International Journal of Molecular Sciences 21, no. 16 (August 6, 2020): 5625. http://dx.doi.org/10.3390/ijms21165625.

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Aromatase inhibitors (AIs) have radically changed the prognosis of hormone receptor positive breast cancer (BC) in post-menopausal women, and are a mainstay of the adjuvant therapy for BC after surgery in place of, or following, Tamoxifen. However, AIs aren’t side effect-free; frequent adverse events involve the musculoskeletal system, in the form of bone loss, AI-associated arthralgia (AIA) syndrome and autoimmune rheumatic diseases. In this narrative review, we reported the main clinical features of these three detrimental conditions, their influence on therapy adherence, the possible underlying molecular mechanisms and the available pharmacological and non-pharmacological treatments. The best-known form is the AIs-induced osteoporosis, whose molecular pathway and therapeutic possibilities were extensively investigated in the last decade. AIA syndrome is a high prevalent joint pain disorder which often determines a premature discontinuation of the therapy. Several points still need to be clarified, as a universally accepted diagnostic definition, the pathogenetic mechanisms and satisfactory management strategies. The association of AIs therapy with autoimmune diseases is of the utmost interest. The related literature has been recently expanded, but many issues remain to be explored, the first being the molecular mechanisms.
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Mahindran, Elancheleyen, Jia Xian Law, Min Hwei Ng, and Fazlina Nordin. "Mesenchymal Stem Cell Transplantation for the Treatment of Age-Related Musculoskeletal Frailty." International Journal of Molecular Sciences 22, no. 19 (September 29, 2021): 10542. http://dx.doi.org/10.3390/ijms221910542.

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Projected life expectancy continues to grow worldwide owing to the advancement of new treatments and technologies leading to rapid growth of geriatric population. Thus, age-associated diseases especially in the musculoskeletal system are becoming more common. Loss of bone (osteoporosis) and muscle (sarcopenia) mass are conditions whose prevalence is increasing because of the change in population distribution in the world towards an older mean age. The deterioration in the bone and muscle functions can cause severe disability and seriously affects the patients’ quality of life. Currently, there is no treatment to prevent and reverse age-related musculoskeletal frailty. Existing interventions are mainly to slow down and control the signs and symptoms. Mesenchymal stem cell (MSC) transplantation is a promising approach to attenuate age-related musculoskeletal frailty. This review compiles the present knowledge of the causes and changes of the musculoskeletal frailty and the potential of MSC transplantation as a regenerative therapy for age-related musculoskeletal frailty.
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Futornyi, Serhii, Olena Maslova, Tetiana Kolomiiets, Liliia Vasylchenko, Tetiana Tereshchenko, and Maksym Hopei. "Methodological Aspects of Health Formation for the Practice of Adaptive Physical Education in School-Children Taking into Account the Endoecological Factors." Sport Mont 19, S2 (September 1, 2021): 207–12. http://dx.doi.org/10.26773/smj.210935.

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Purpose of the research to define and characterize the projection theory of scientific knowledge prerequisites on the concept of health-forming technologies development in the process of adaptive physical education for school-age children with hearing impairment. The study involved 236 pupils. Depending on age, gender and degree of hearing impairment, pupils were divided into 8 groups. Studied physical development, physical work capability, physical preparedness, morbidity, level of health and peculiarities of children with hearing impairments attitude`s to their own health for substantiation of methodical provisions to concept of health formation for children with hearing impairments. According to the Kettle index, none of the groups of surveyed pupils met the norm. Data showed that almost 60.00% of children were below the average for the vital index, and 40.00% are at the low level. In the morbid- ity structure of hard-hearing and deaf pupils, regardless of age and gender, the first place was occupied by infectious and parasitic diseases (86.97%), followed by diseases of the nervous system (76.54%) and musculoskeletal system (81.78%). Children with hearing impairments had below average of recovery rate of the cardiovascular system after a standard exercise (57.80%). Only 15.70% of boys and 28.40% of girls considered themselves as practically healthy. All data determine the urgent need for focusing attention on the children with hearing impairments health.
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Borodin, Sergiy, Yuriy Tuharov, Danylo Ostapchenko, Larysa Kot, and Oleksandr Korotkyi. "VIEW OF THE PATHOGENETIC MECHANISMS OF JOINT DAMAGE IN CORONAVIRUS DISEASE 2019." Bulletin of Taras Shevchenko National University of Kyiv. Series: Biology 89, no. 2 (2022): 5–9. http://dx.doi.org/10.17721/1728.2748.2022.89.5-9.

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The Сoronavirus disease 2019 (COVID-19) pandemic has had an extremely serious impact on the livelihoods of people worldwide. Despite the mainly respiratory manifestations of SARS-CoV-2 infection, its consequences can affect the functioning of most systems of organism, including the musculoskeletal, dysfunction of which is a leading factor in disability of the population. Diseases of the joints are one of the most common pathologie of modernity, which in the last decade are increasingly found in young people and even children. The musculoskeletal symptoms can be observed as isolated clinical signs and expressed regardless of the severity of the viral disease. Chronic fatigue, myalgia, swelling and joint pain may occur during the acute phase of COVID-19 and as short-term or long-term complications, but their prevalence has not been systematically studied. Considering the wide range of clinical manifestations of SARS-CoV-2 infection and the complexity of their pathogenesis, the mechanisms underlying lesions of musculoskeletal system and rheumatological complications remain unclear. Today, the main research in this direction is focused mainly on a complete understanding of the regulatory pathways of immune dysregulation and inflammation. Excessive secretion of pro-inflammatory cytokines, disruption of signal transduction and immune response are the result of the severe impact of SARS-CoV-2 infection on most organs, including joints, as well as the use of corticosteroids for the treatment of patients with COVID-19. The presented review highlights generalized information on the main pathophysiological processes that can occur in the joints as a manifestation of the impact of SARS-CoV-2 infection, and possible key mechanisms which contribute to the progression of pathological changes.
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Latoguz, S. I., and H. L. Lytvynenko. "Peculiarities of Physical Therapy in Humeroscapular Periarthritis." Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 7, no. 4 (August 30, 2022): 111–15. http://dx.doi.org/10.26693/jmbs07.04.111.

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The purpose of the study was to develop a comprehensive program of physical rehabilitation to improve the course of shoulder-scapular periarthritis in patients with the help of therapeutic massage with elements of manual therapy. Materials and methods. The paper presents the results of studying the effect of physical therapy in shoulder-scapular periarthritis. The main group included 37 patients aged 50–75 years with shoulder-scapular periarthritis who underwent a complex rehabilitation program proposed by us, including massage. The control group consisted of 33 patients in the same age category who were prescribed a standard rehabilitation program by a physical therapy doctor. Results and discussion. The term humeroscapular periarthritis was first proposed in 1872. This is how the syndrome was characterized, including stiffness and the presence of chronic pain in the area of the shoulder joint that occurs after an injury. The prevalence of humeroscapular periarthritis among the adult population is 4–7%, with age it increases (from 3–4% at the age of 40–44 years to 15–20% at the age of 60–70 years). An important condition for a faster and more effective treatment of humeroscapular periarthritis is massage. Its main task is to prevent the development of limited mobility of the joints and coarse scar tissue, prevent muscle atrophy and restore the functional affiliation of the upper limbs. As a result of the treatment, significant improvement was noted in 26 patients, improvement – in 9 patients, insignificant effect was noted in 2 patients. So, before the operation, pain syndrome according to visual analogue scale was on average 6.4 ± 0.39, in the early postoperative period – 5.1 ± 0.19, in the late recovery period – 1.7 ± 0.14. The effectiveness of complex treatment when affecting the affected limb was 3.4 points in dynamics before and after the massage course. Thus, the comparative characteristics of the two examined groups of patients according to functional results, even according to an incomplete list of clinical and biomechanical indicators of statics and dynamics, showed the effectiveness of conducting a comprehensive program of rehabilitation measures. Taking into account the high prevalence of diseases of the musculoskeletal system, we consider it advisable to use manual therapy methods more widely in patients with shoulder-scapular periarthritis. Conclusion. After a course of massage with elements of manual therapy, the majority of patients noted positive dynamics, elimination of pain syndrome, restoration of the function of the affected limb
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Skyba, V. V., V. F. Rybalchenko, A. V. Ivanko, and Dar Yasin Akhmed. "Epidemiology of intra-abdominal infiltrates and abscesses in patients with concomitant diseases and diabetes mellitus." Clinical Endocrinology and Endocrine Surgery, no. 1 (December 6, 2021): 27–36. http://dx.doi.org/10.30978/cees-2021-1-27.

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The purpose ofthe work — to study the epidemiological factors in the development of primary and secondary intra-abdominal infiltrates, abscesses and fluid formations in patients with concomitant diseases and diabetes. Material and methods. In the clinic of the Department of Surgical Diseases No. 1, on the basis of the Center of Surgery of the Kiev City Clinical Hospital No. 1 from 2006 to 2019,218patients with primary and secondary intra-abdominal infiltrates, abscesses and fluid formations were treated. The patients’ age ranged from 16 to 85 years. There were 107 male patients (49.08 %), 111 female patients (50.92 %). X-ray examination was performed in 112 (51.38 %) patients, computed tomography (CT) in 25 (11.48 %),ultrasound examination of the abdominal organs for 105 (4816 %) patients. Anterior abdominal wall thermometry was performed in 76 (34.86 %) patients. Resultsand discussion. Depending on the cause of the development of intra-abdominal infiltrates, abscesses and fluid formations, the patients were divided into 4 groups. Patients of the first, second and third groups had primary intra-abdominal complications, and in the fourth group patients had secondary postoperative complications. The first group included 74 (33.94 %) patients suffering from a complicated course of destructive appendicitis. The second group included 48 (22.02 %) patients suffering from perforated gastric ulcer and 12 duodenal ulcer. The third group included 69 (31.65 %) patients suffering from cholecystitis and various types of complications. The fourth group included 27 (12.39 %) patients who underwent urgent surgery due to strangulated hernias, adhesive obstruction. The study of the scales showed that: in 87 (39.91 %) the weight was within normal limits, and in 131 (60.09 %) patients were overweight and obese. It was found that 126 (57.80 %) patients wore glasses. Diseases of the cardiovascular system and arterial pressure disorders according to the data of case histories and anamnesis had 123 (56.42 %) patients. Diabetes was diagnosed in 38 (17.43 %) patients. Diseases of the musculoskeletal system were diagnosed in 27 (12.38 %) patients, and 48 (22.02 %) patients suffered from flat feet of various stages. Primary intra-abdominal complications(infiltrates and abscesses) were diagnosed in 191 (3.48 %) patients out of 5483 urgent hospitalizations and operations, of which 74 (1.35 %) with appendicitis, 69 (1.26 %), perforated gastric ulcer and 12 duodenal ulcer in 48 (0.87 %) patients. Secondary postoperative infiltrates, abscesses and fluid formations were found in 27 (18.12 %) of 149 patients who had undergone urgent abdominal surgery (adhesive obstruction, incarcerated and postoperative hernias, etc.), and in 29 (15.18 %) of 191 patients who underwent surgery for primary intra-abdominal complications of the underlying disease and urgent surgery. Diabetes mellitus was diagnosed in 38 (17.4 3%) patients, and therefore all patients who are hospitalized in an urgent and planned manner must undergo a comprehensive clinical and laboratory examination with the determination of blood sugar. The presence of established diabetes mellitus requires the consultation of an endocrinologist, and during the operation it is advisable and necessary to correct glycemic and volemic disorders, which continues until the restoration of vital functions and stabilization of the general condition of the patient. Intra-abdominal complications occurred on the background of concomitant diseases: overweight in 28.44 %, visual impairment in 57.80 %, diseases of the cardiovascular system and arterial pressure disorders in 56.42 %, diseases of the musculoskeletal system in 12.38 %, which indicates the need for an individual approach in the treatment of each patient.
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SAKOVETS, TATIANA G., ENVER I. BOGDANOV, GULNARA R. KHUZINA, and ELENA N. BARYSHEVA. "ANALYSIS OF THE SPECIFIC FEATURES OF THE USE OF PHYSIOTHERAPEUTIC METHODS IN PATIENTS WHO UNDERWENT ARTHROSCOPIC OPERATIONS ON THE KNEE JOINT IN 2018–2019 AT THE MEDICAL UNIT OF THE MINISTRY OF INTERNAL AFFAIRS OF RUSSIA IN THE REPUBLIC OF TATARSTAN." Bulletin of Contemporary Clinical Medicine 14, no. 5 (October 2021): 51–55. http://dx.doi.org/10.20969/vskm.2021.14(5).51-55.

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Background. Diseases of the musculoskeletal system are the most common cause of disability in the modern world, and the prevalence of these diseases is increasing at an alarming rate. Currently, various types of arthroscopic operations on the knee joint are performed – for meniscus damage (including meniscus suture), instability of the knee joint, damage to the cruciate complex, articular cartilage, patellar instability, free joint bodies, pathological folds, synovitis, knee arthrosis, and rheumatoid arthritis. Medical rehabilitation after arthroscopic surgery traditionally includes administration of nonsteroidal anti-inflammatory drugs, opioids, local anesthetics, therapeutic exercise using isometric active exercises, hydrokinesis therapy, and various physical therapy methods. Aim. Study of the use of physiotherapeutic methods in the treatment of patients who underwent atroscopic surgery on the knee joint in the physiotherapy department at the Ministry of Internal Affairs of Russia for the Republic of Tatarstan Clinical Hospital in 2018–2019. Material and methods. The frequency of prescription of therapeutic physical factors for patients who underwent arthroscopic surgeries on the knee joint at the physiotherapy department at the Medical Unit of Ministry of Internal Affairs of Russia for the Republic of Tatarstan Clinical Hospital in 2018–2019 was investigated. The patients were accordingly divided into two groups: in 2018, 37 patients were prescribed physiotherapeutic procedures, in 2019 there were 48 patients. The age of the patients in 2018 was (33,9±9,4) years, in 2019 it was (34,2±9,1) years. Statistica 6 software package by StatSoft was used for statistical processing. Differences were considered statistically significant at p<0,05. Results and discussion. Paraffin therapy, treatment using Nuga-Best bed, amplipulse therapy, UHF therapy, cryotherapy, oxygen cocktails containing medicinal herbs were prescribed with less frequency in the treatment of patients operated for knee joint injuries in 2018 than in 2019. Despite the proven effectiveness of whirlpool baths and darsonvalization in treating musculoskeletal disorders were not prescribed for the rehabilitation of patients who underwent atroscopic surgeries at the physiotherapy department of Medical Unit of Ministry of Internal Affairs of Russia for the Republic of Tatarstan Clinical Hospital in 2019. Conclusion. When rehabilitating patients who have undergone arthroscopic intervention on the knee joint, it is advisable to thoroughly consider the use of therapeutic physical factors to improve the operation of the physiotherapy department.
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Valaas, Helene Lindtvedt, Mari Klokkerud, Julie Hildeskår, Anne S. Hagland, Egil Kjønli, Kristin Mjøsund, Lars Øie, et al. "Associations Between Adherence to Self-Management Activities and Change in Function and Health Outcomes in the Rehabilitation of Patients with Rheumatic and Musculoskeletal Diseases." Journal of Rehabilitation Medicine 55 (January 12, 2023): jrm00362. http://dx.doi.org/10.2340/jrm.v55.2214.

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Objectives: To explore the content of, and adherence to, self-management activities reported by patients with rheumatic and musculoskeletal diseases (RMDs), and whether adherence to self-management activities is associated with changes in self-reported health and function over a 1-year period following rehabilitation in specialized healthcare.Methods: Participants (n = 523) reported function and health outcomes at admission, discharge, and 4, 8 and 12 months post-rehabilitation. Self-management activities reported at discharge were self-evaluated as adherence level at home. Self-management activity content was linked to the International Classification of Functioning, Disability and Health coding system, and summarized as high or low adherence. Associations between adherence to self-management activities and change in outcomes were investigated using a linear mixed model approach with repeated measures.Results: Self-management activities focused mainly on enhanced physical health and managing everyday routines, and seldom addressed work participation. Adherence to self-management activities was challenging with regard to structure and daily life routines, mental health, and the application of knowledge and coping strategies. Adherence to self-management activities was significantly associated with improvements in all outcomes, except for mental health and activities of daily living.Conclusion: Adherence to self-management activities, and creating structure and setting everyday routines at home, appear to be important for maintaining health and function over time. Rehabilitation should include a greater focus on mental health challengesand work participation. LAY ABSTRACTThe aim of this study is to explore the self-management plans reported by patients with rheumatic and musculoskeletal diseases, and whether these plans influenced patients’ health and function after rehabilitation. The participants were followed for 1 year after undergoing rehabilitation and into their home settings. They self-reported their self-management plans, and self-evaluated their adherence to these plans at home. The plans focused mainly on physical health and managing everyday routines. It appears that creating structure and setting routines at home are important for maintaining health and function over time. It was notable that mental health challenges and plans for work participation were seldom prioritized or improved, suggesting a need for greater focus on these issues by healthcare professionals during rehabilitation and in the community.
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Dalvand, Hamid, Leila Dehghan, Hooshang Dadgar, Saman Maroufizadeh, and Sarvin Sarmadi. "Periodontal Diseases and Dental Caries in Children With Cerebral Palsy." Iranian Rehabilitation Journal 19, no. 3 (September 1, 2021): 289–96. http://dx.doi.org/10.32598/irj.19.3.1410.1.

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Objectives: Musculoskeletal disorders in children with Cerebral Palsy (CP) affect the general health of the mouth and teeth. This study aimed to determine periodontal and dental diseases in children with CP based on gross motor function level, manual ability level, and subtypes of CP. Methods: This research was a cross-sectional study performed on 123 children (3-18 years old) with CP referred to dentistry and rehabilitation centers supervised by Tehran University of Medical Sciences in 2019-2020. They were selected by the convenience sampling method. The children were classified according to the gross motor function classification system: expanded and revised (GMFCS-E&R) for their gross motor function level, according to the manual ability function classification system (MACS) and mini-MACS for the functioning of their hands in handling objects, and according to the quality and topographical pattern of motor impairment for subtypes of CP. The periodontal status of children with CP was evaluated according to the recommendation of the World Health Organization using the community periodontal index and for caries according to the decayed, missing, filled index. All statistical analyses were done by SPSS v. 16. Results: The results showed significant differences between periodontal disease and sex, age, GMFCS-E&R, MACS, mini-MACS levels, and subtypes of CP (P<0.05). But there were no significant differences between teeth diseases and oral motor skills with sex, age, MACS and mini-MACS, GMFCS-E&R levels, and subtypes of CP (P>0.05). Discussion: Periodontal disease and decayed, missing, filled teeth are common problems in CP children, and the conditions worsen with age and level IV and V of GMFCS-E&R and MACS.
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Prusiazhnyk, Ulyana, and Andriy Vovkanych. "Methods of inspection of flat-valgus deformation of foot in the conditions of a specialized preschool institution or at home." Ukrainian Scientific Medical Youth Journal 132, no. 3 (September 28, 2022): 29–37. http://dx.doi.org/10.32345/usmyj.3(132).2022.29-37.

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during the first years of a child's life, he grows intensively, perceives and learns about the world around him, all the systems of his child's body are actively developing, in particular, it is worth noting the muscular and bone systems that form the musculoskeletal system of a person. Diseases of the musculoskeletal system (MSD) are among the most common in children of preschool and primary school age. The main factor affecting the development of ORA pathologies can be considered the weakness of the muscular system, since muscles at this age are characterized by a high ability to stretch and do not provide reliable fixation of bones. The bones themselves are characterized by less hardness and greater plasticity than the bones of adults, they are more easily deformed under the influence of external factors. As a result, we quite often have the opportunity to observe acquired pathologies of the musculoskeletal system in preschool children, such as clubfoot, x-shaped feet, flat feet, flat-valgus or varus foot deformity. In turn, diseases of the lower extremities provoke diseases of the spine, in particular, postural disorders and their varieties. In order to timely detect the manifestations of diseases of the lower extremities, it is important to be able to conduct an examination and analyze it correctly. The purpose of this article is to highlight the methods of examining the feet of preschool children, which are easy to perform, and also possible to use at home or in the conditions of a specialized preschool institution. Research methods: analysis and generalization of data from scientific and educational and methodological literature regarding the main diseases of the lower extremities, methods of their examination and methods of conducting these examinations in the conditions of specialized preschool institutions or at home. The obtained results - based on the analysis of the main methods of foot examination, those of them were selected, which, on the one hand, are quite easy to implement in practice in a specialized children's preschool or at home, which do not require the presence of complex and expensive equipment, and can also be carried out independently by employee’s institution of preschool education, and, on the other hand, ensure the proper validity of the obtained results. The practical significance of the scientific work is that the algorithm for carrying out and evaluating the obtained data is prescribed, which can be applied in the conditions of a specialized preschool institution or at home (Friedland's pedometric index using a compass and a ruler; contourography; measurement of the volume of the feet). Their application enables in digital format or visually the results of a physical therapy program for the treatment of flat-valgus deformity of the feet. It is no less important that these methods can be used in the form of a game, which is an important factor for examining children, especially preschoolers.
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Bojičić, Samir, Dijana Avdić, Bakir Katana, Amila Jaganjac, and Amra Mačak Hadžiomerović. "Efficiency of combined treatment and conventional physical treatment in bilateral knee arthrosis." Journal of Health Sciences 3, no. 1 (April 15, 2013): 70–74. http://dx.doi.org/10.17532/jhsci.2013.33.

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Introduction: Degenerative joint disease, which is standardized in Europe by the name of arthrosis or osteoarthrosis, while in the Anglo-Saxon literature is in use for a long time by the name of osteoarthritis (OA) although this is not a classical inflammation,is the most common joint disease in general and the most common cause of functional damage of the musculoskeletal system. Recently, the term osteoarthritisappears more frequently in domestic literature. Arthroses are degenerative joint diseases with progressive character, also one of the most frequent diseases in orthopedics. The disease fi rst affects the articular cartilage, then the bony edges of the articular surfaces, and then the articular lining.Methods: Retrospective analysis and evaluation of data of treated patients, with the "Praxis" physical treatment during the period of time from 2000 to the end of 2010 on a sample of 79 patients,valorized the efficacy of Praxis treatment. The correlation of these results, with valorisation of the efficacy of standard physical treatment in clinics D.Z. " Novi Grad " on a sample of 81 patients, during the period of time from 2000 to the end of 2010, a statistical analysis was performed for comparing the effi cacy of the two methods.Results: There is a functional difference after therapy of bilateral gonarthrosis in clinics D.Z. "Novi Grad" and "Praxis" with statistical reliability.Conclusion: A combined approach in the treatment of knee arthrosis has a wider range of treatment procedures, comprehensively approaches to the problem and gives better results, so we can say that this method has priority compared to the standard approach to the knee arthrosis treatment.
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Нnatiuk, V. V., and L. V. Ocheredko. "Theoretical Substantiation of the Complex Application of Vacuum Therapy and Kinesiotherapy in Chronic Wound Process." Ukraïnsʹkij žurnal medicini, bìologìï ta sportu 6, no. 5 (October 27, 2021): 342–49. http://dx.doi.org/10.26693/jmbs06.05.342.

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The purpose of the study was to substantiate theoretically the possibility of complex application of vacuum therapy and kinesiotherapy in elderly people with chronic wound healing. Materials and methods. The methodological approach was used in the study: an analysis of literary sources and Internet resources; analysis of advanced foreign and domestic experience, system analysis method, comparison method, organizational analysis. Results and discussion. Vacuum therapy of wounds is considered as an additional method of treatment in patients with chronic wounds and wounds that heal for a long time, which is especially important for the elderly people because of the slowed metabolism and reduced immunological resistance of the body. Vacuum therapy stimulates wound healing by using localized negative pressure on the surface of the wound, and helps to remove excess of exudate around and within the wound. Another method of physical therapy which has a positive effect on the processes of recovery or recuperation of motor function, reducing the risk of complications (thromboembolism, respiratory diseases, pressure ulcers, contractures) and maintaining the patient's overall physical ability is kinesiotherapy. Kinesiotherapy, the main meaning of which is physical exercise, is aimed at improving aerobic performance, muscle performance of strength and endurance, stretching and lengthening of muscles, mechanisms of neuro-muscular control of inhibition and excitation. Any exercise activates not only the musculoskeletal system, but also all body systems, including nervous, hormonal, immune, which significantly accelerates the healing process. The main meaning of physical exercise, along with the use of vacuum therapy, is the dosed performance of physical activity with a healthy limb or a segment of the body to improve trophicity in tissues to achieve a general tonic and trophic effect caused by physical exercise for a faster resorption of inflammation products, preventing the appearance of hyperproliferative processes in wounds. Conclusion. It was theoretically substantiated that the combined use of negative pressure therapy and kinesiotherapy can lead to a reduction in the time of complete wound healing and a decrease in the time of temporary disability / inability to self-care, as well as contribute to an earlier restoration of daily activity. Exercise for the elderly may include: aerobic exercise to improve endurance and recovery; body mechanics training; breathing exercises for the prevention of congestion in the lungs; exercises to develop coordination of movements; self-care skills training; ideomotor exercises; perception training; exercises for the amplitude of movements and stretching of soft tissues; relaxation exercises; exercises for general strengthening, strength and endurance
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Ferrillo, Martina, Amerigo Giudice, Nicola Marotta, Francesco Fortunato, Daniela Di Venere, Antonio Ammendolia, Pietro Fiore, and Alessandro de Sire. "Pain Management and Rehabilitation for Central Sensitization in Temporomandibular Disorders: A Comprehensive Review." International Journal of Molecular Sciences 23, no. 20 (October 12, 2022): 12164. http://dx.doi.org/10.3390/ijms232012164.

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Temporomandibular disorders (TMD) are a group of musculoskeletal diseases affecting masticatory muscles and temporomandibular joints (TMJ). In this context, the chronic TMD could be considered as a condition with chronic primary orofacial pain, presenting as myofascial TMD pain or TMJ arthralgia. In this context, myogenous TMD may present overlapping features with other disorders, such as fibromyalgia and primary headaches, characterized by chronic primary pain related to dysfunction of the central nervous system (CNS), probably through the central sensitization. This phenomenon could be defined as an amplified response of the CNS to sensory stimuli and peripheral nociceptive, characterized by hyperexcitability in the dorsal horn neurons in the spinal cord, which ascend through the spinothalamic tract. The main objectives of the management of TMD patients are: decreasing pain, increasing TMJ function, and reducing the reflex masticatory muscle spasm/pain. The first-line treatments are physical therapy, pharmacological drugs, occlusal splints, laser therapy, extracorporeal shockwave therapy, transcutaneous electrical nerve stimulation, and oxygen–ozone therapy. Although all these therapeutic approaches were shown to have a positive impact on the central sensitization of TMD pain, there is still no agreement on this topic in the scientific literature. Thus, in this comprehensive review, we aimed at evaluating the evidence on pain management and rehabilitation for the central sensitization in TMD patients.
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Tchorowska, Ewa, Iwona Wilk, and Krzysztof Kassolik. "Assessment of the effectiveness of massage for spinal pain as part of primary healthcare: a pilot study." Medical Science Pulse 15, no. 1 (June 14, 2021): 1–11. http://dx.doi.org/10.5604/01.3001.0014.9273.

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Background: Pain in the spine is one of the most common issues in the musculoskeletal system. 70–80% of the population experiences an acute spine pain incident at least once in their life, and 50% struggle with a chronic form of this health problem. Factors contributing this situation include static work, a sedentary lifestyle, a minimal amount of physical activity, stress, and poor nutrition. Massage is among the many therapeutic methods used for the treatment of back pain. This is a non-invasive method that involves manipulation of the soft tissues of the musculoskeletal system, where symptoms directly related to the disease appear. Aim of the Study: The aim of this study was to assess the effectiveness of tensegrity massage therapy for lumbar spine pain. The study presents the possibility of cooperation between the physiotherapist and primary care physician as part of primary health care. Material and Methods: The study involved 25 participants (15 women and 10 men) diagnosed with pain in the lumbar spine. The participants were aged 23–70 years with a mean age of 50 years (SD ± 14.77). Pain was assessed using the visual analogue scale (VAS) at rest and during a functional test, and functional disability was measured using the Oswestry Disability Index (ODI). Measurements were taken before and immediately after therapy. A palpation assessment was performed before each massage session. The therapy consisted of six 45-minute tensegrity massage sessions performed twice a week for three weeks. Results: Pain during the functional test and the subjective feeling of pain measured by the VAS decreased following treatment. The ODI results revealed a significant improvement from moderate to low disability. The results obtained were statistically significant (p < 0.05). Conclusions: Tensegrity massage contributed to a reduction in back pain and improved the functioning of the patient. This therapy can be a complementary method to conservative treatments for spinal diseases.
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Petrova, Maria S., and Maya A. Khan. "Health Resort Treatment for COVID-19 Patients: a Review." Bulletin of Rehabilitation Medicine 21, no. 4 (August 31, 2022): 27–32. http://dx.doi.org/10.38025/2078-1962-2022-21-4-27-32.

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INTRODUCTION. To date, one of the important tasks of Russian healthcare is the development and improvement of sanatorium treatment. The article highlights topical issues of development and improvement of sanatorium treatment of children in institutions subordinate to the Administrative Department of the President of the Russian Federation. It presents the data on the peculiarities of the functioning of the II and III stages of medical rehabilitation in the conditions of health resort institutions on the basis of the rehabilitation department of the children’s sanatorium “Polyany”, where a wide range of innovative technologies of physiotherapy and kinesiotherapy are successfully applied. The high availability of sanatorium-resort treatment for children registered at a dispensary in a Children’s medical center is shown. Data are published on the effective use of the bed capacity of health resort institutions subordinate to the Administrative Department of the Russian Federation, primarily for the treatment and medical rehabilitation of children with chronic diseases. The article describes the organization and modern technologies of medical rehabilitation of children with diseases of musculoskeletal system, respiratory organs, digestion, genitourinary system, in institutions subordinated to the Administrative Department of the President of the Russian Federation. There are data on the organization of medical rehabilitation of children who have had COVID-19. A 3-stage system of restorative treatment, indications and non-drug technologies of medical rehabilitation of such patients are shown. AIM. To assess the current state of the health resort care for children in institutions subordinate to the Administrative Department of the President of the Russian Federation. CONCLUSION. In order to further improve the sanatorium treatment of children in institutions subordinate to the Administrative Department of the President of the Russian Federation, there are of the necessity: a personalized approach to the development of sanatorium-treatment programs for children, an optimization of the II and III sanatorium stages of medical rehabilitation of children, an introduction of innovative technologies of medical rehabilitation of children in the practical activities of sanatoriums, an integration of research results into the practice of s-anatorium treatment of children and continuous professional development of specialists, working in health resorts.
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Kitaeva, J. S., E. A. Praskurnichy, and M. I. Pereginets. "Reduction of Bone Mineral Density in Patients with Lymphoproliferative Diseases." A.I. Burnasyan Federal Medical Biophysical Center Clinical Bulletin, no. 3 (October 2022): 53–60. http://dx.doi.org/10.33266/2782-6430-2022-3-53-60.

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In recent years, the incidence of hemoblastoses has not changed significantly, but the mortality rate has decreased and the life expectancy of patients has increased. The prognosis of survival with these diseases using modern methods of treatment is relatively favorable. In most patients, after the use of standard first-line polychemotherapy, a cure is possible. Autologous hematopoietic stem cell transplantation is a modern and very effective method of treatment for relapsed or refractory course, the use of which is accompanied by an increase in the number of cured patients. However, an increase in the survival rate in lymphoproliferative diseases is associated with an increase in the likelihood of complications of previous cytostatic therapy, the frequency of patient disability or death. Among the many long-term complications of polychemotherapy and autologous hematopoietic stem cell transplantation, pathology of the musculoskeletal system is revealed, which develops as a result of metabolic bone lesions – osteoporosis and associated low-energy fractures. The mechanisms of osteoporosis development in patients with lymphoproliferative diseases are not well understood, however, there are a number of literature sources in which a decrease in bone mineral density is presented as a consequence of a violation of the formation and destruction of bone tissue, increased bone resorption. In turn, the reasons for the decrease in bone mineral density are the use of cytostatic drugs, glucocorticosteroids, nutritional deficiency, physical inactivity. In this context, the problems of diagnosing and preventing osteoporosis seem to be very relevant for modern oncohematology. The purpose of this literature review is to identify the main patterns of bone tissue processes in patients with lymphoproliferative diseases.
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Saakyan, Svetlana V., Olga A. Ivanova, Syuzanna S. Revishvili, and Alexander I. Tsygankov. "Somatic state assessment of the health of patients with retinoblastoma in a long-term follow-up." Russian Pediatric Ophthalmology 16, no. 4 (December 15, 2021): 13–20. http://dx.doi.org/10.17816/rpoj83408.

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AIM: To comprehensively assess the incidence and nature of the chronic diseases in patients with retinoblastoma in the long-term follow-up MATERIAL AND METHODS: The study analyzed the long-term treatment results of 176 patients with retinoblastoma. Group 1 included 46 patients aged 18 years and Group 2 included 88 patients aged 18 and 35 years. A gynecologist and a urologist were consulted, a medical history was taken, and a physical examination with emphasis on the presence of secondary sexual characteristics and laboratory tests were performed to assess the endocrine function in surviving patients aged 18 years. Anamnestic data were used in patients aged 18 years. RESULTS: The somatic status data analysis of 46 surviving adolescents revealed that 29 (63%) have abnormalities. Chronic gastritis and gastroduodenitis, biliary dyskinesia, fatty hepatosis, and lactase deficiency predominate in gastrointestinal structure diseases. Respiratory diseases are represented by chronic nasopharyngeal diseases in 13.0% of children. Secondary immunodeficiency condition was diagnosed in 3 (6.5%) patients. Musculoskeletal system and connective tissue pathologies in deforming dorsopathies were identified in 10.9% of cases and bone and joint pain were identified in 8.7%. Chronic conditions were found in 42 (47.7%) of 88 patients in Group 2. Somatic disorders were found in 95.2%, hormonal disorders in 11.9%, psycho-emotional disorders in 9.5%, and combined pathology in 9.5% of cases. Endocrine pathology was detected in 14 patients (30.4%) aged 18 years. CONCLUSION: Retinoblastoma survivors have a high risk of somatic and endocrine disorders. The main risk factors are distance radiation therapy and alkylating agents. Regular lifelong follow-up of these patients is necessary to establish a medical rehabilitation system for children with retinoblastoma.
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de Lima, Maria do Carmo Correia, Mathieu Dallaire, Catherine Tremblay, Alexis Nicole, Émilie Fortin, Isabela Calixto Maluf, Josée Nepton, et al. "Physical and Functional Clinical Profile of Older Adults in Specialized Geriatric Rehabilitation Care Services in Saguenay-Québec: A Retrospective Study at La Baie Hospital." International Journal of Environmental Research and Public Health 19, no. 16 (August 13, 2022): 9994. http://dx.doi.org/10.3390/ijerph19169994.

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Musculoskeletal disorders, cardiovascular and neurological diseases were the most commonly debilitating conditions and risk factors associated with pain, mobility limitations, increased risk of falls and disability. Studies barely address the profile of older adults in care within a specialized geriatric rehabilitation service (SGRS) to provide subsidies for new actions within the public healthcare to reduce falls and improve management in health investments. This study aimed to establish a clinical physical and functional profile of the patients with neuromusculoskeletal and cognitive disorders and fallers in interventions within SGRS. From a retrospective study design, 127 medical records were compiled and analyzed to determine the physical and functional profile of older adults and differences according to sex, age groups and the benefits for local physical therapy intervention. The users were between 76 and 85 years of age, with diverse clinical diagnoses and debilitating conditions and impairments. A higher proportion presented gait and balance impairments and had two or more falls in 12 months. A significant effect for advanced age was observed. Overall, real benefits were reported with intervention for functional improvement, although the absence of a control group. These results have direct implications for a better understanding of a local SGRS and provide subsidies for developing new approaches for the assessment and treatment of older adults with high a risk of falls in order to reduce costs for the public health system.
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Nan, Haiyan, Chanbum Park, and Sungho Maeng. "Mucopolysaccharidoses I and II: Brief Review of Therapeutic Options and Supportive/Palliative Therapies." BioMed Research International 2020 (December 4, 2020): 1–18. http://dx.doi.org/10.1155/2020/2408402.

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Purpose. Mucopolysaccharidoses (MPS) are group of inherited lysosomal storage diseases caused by mutations of enzymes involved in catalyzing different glycosaminoglycans (GAGs). MPS I and MPS II exhibit both somatic and neurological symptoms with a relatively high disease incidence. Hematopoietic stem cell therapy (HSCT) and intravenous enzyme replacement therapy (ERT) have had a significant impact on the treatment and comprehension of disease. This review is aimed at providing a comprehensive evaluation of the pros and cons of HSCT and ERT, as well as an up-to-date knowledge of new drugs under development. In addition, multiple disease management strategies for the uncontrollable manifestations of MPS I and MPS II to improve patients’ quality of life are presented. Findings. Natural history of MPS I and MPS II shows that somatic and neurological symptoms occur earlier in severe forms of MPS I than in MPS II. ERT increases life expectancy and alleviates some of the somatic symptoms, but musculoskeletal, ophthalmological, and central nervous system (CNS) manifestations are not controlled. Additionally, life-long treatment burdens and immunogenicity restriction are unintended consequences of ERT application. HSCT, another treatment method, is effective in controlling the CNS symptoms and hence has been adopted as the standard treatment for severe types of MPS I. However, it is ineffective in MPS II, which can be explained by the relatively late diagnosis. In addition, several factors such as transplant age limits or graft-versus-host disease in HSCT have limited its application for patients. Novel therapies, including BBB-penetrable-ERT, gene therapy, and substrate reduction therapy, are under development to control currently unmanageable manifestations. BBB-penetrable-ERT is being studied comprehensively in the hopes of being used in the near future as a method to effectively control CNS symptoms. Gene therapy has the potential to “cure” the disease with a one-time treatment rather than just alleviate symptoms, which makes it an attractive treatment strategy. Several clinical studies on gene therapy reveal that delivering genes directly into the brain achieves better results than intravenous administration in patients with neurological symptoms. Considering new drugs are still in clinical stage, disease management with close monitoring and supportive/palliative therapy is of great importance for the time being. Proper rehabilitation therapy, including physical and occupational therapy, surgical intervention, or medications, can benefit patients with uncontrolled musculoskeletal, respiratory, ophthalmological, and neurological manifestations.
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Yakovlev, E. V., E. N. Gnevyshev, S. A. Zhivolupov, A. A. Smirnov, Yu A. Zhivolupova, A. I. Eriskovskaya, and A. L. Ovsepyan. "Evaluation of the therapeutic efficacy of original and generic meloxicam in the treatment of acute neck pain." Meditsinskiy sovet = Medical Council, no. 21-1 (January 6, 2022): 25–33. http://dx.doi.org/10.21518/2079-701x-2021-21-1-25-33.

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Introduction. In the structure of the global burden of diseases, back pain ranks first in the world in the list of causes of disability. Neck pain is one of the most common diseases of the musculoskeletal system. An integral part of the strategy for the treatment of acute neck pain is the use of original nonsteroidal anti-inflammatory drugs (NSAIDs) with high proven effectiveness.Objective. To conduct a comparative analysis of the therapeutic efficacy of the original drug meloxicam (Movalis) and its generic (Amelotex) in the treatment of patients with acute nonspecific musculoskeletal pain of cervical localization.Materials and methods. The article provides an assessment of the therapeutic effectiveness of the original drug meloxicam (Movalis) and its generic (Amelotex) in the treatment of patients with acute neck pain. Comparative analysis of the results of treatment of 108 patients hospitalized in the Branch of the MC JSC “Admiralteyskie Verfi” aged 18 to 60 years (58 men and 50 women) with a diagnosis of acute dorsalgia of cervical localization (M54.2 according to ICD-10). The average age of patients is 42.5 ± 11.1 years.Results. As a result of the clinical and neurological study and statistical processing of the data obtained, it was found that the use of Movalis in the treatment of patients with acute neck pain was more effective compared to the use of generic (Amelotex). In the Movalis group, the level of pain intensity and the index of disability after treatment was significantly lower than in the Amelotex group at an equivalent dose of 15 mg per day (p < 0.01). The analgesic effect in the group of patients receiving Movalis was longer. There was a significant decrease in sleep disorders associated with pain syndrome in the group (Movalis) compared with patients of the second group (Amelotex). Conclusions. The absence of therapeutic bioequivalence between Movalis and Amelotex revealed in our study determines the relevance of the choice of drugs for the complex therapy of patients of this profile. A multimodal approach to the strategy of treating neck pain, individually patient-oriented, including the use of effective and safe medicines, physical exercises, manual therapy, is optimal.>< 0.01). The analgesic effect in the group of patients receiving Movalis was longer. There was a significant decrease in sleep disorders associated with pain syndrome in the group (Movalis) compared with patients of the second group (Amelotex).Conclusions. The absence of therapeutic bioequivalence between Movalis and Amelotex revealed in our study determines the relevance of the choice of drugs for the complex therapy of patients of this profile. A multimodal approach to the strategy of treating neck pain, individually patient-oriented, including the use of effective and safe medicines, physical exercises, manual therapy, is optimal.
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Di Marcello, Francesca, Giulia Di Donato, Debora Mariarita d’Angelo, Luciana Breda, and Francesco Chiarelli. "Bone Health in Children with Rheumatic Disorders: Focus on Molecular Mechanisms, Diagnosis, and Management." International Journal of Molecular Sciences 23, no. 10 (May 20, 2022): 5725. http://dx.doi.org/10.3390/ijms23105725.

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Bone is an extremely dynamic and adaptive tissue, whose metabolism and homeostasis is influenced by many different hormonal, mechanical, nutritional, immunological and pharmacological stimuli. Genetic factors significantly affect bone health, through their influence on bone cells function, cartilage quality, calcium and vitamin D homeostasis, sex hormone metabolism and pubertal timing. In addition, optimal nutrition and physical activity contribute to bone mass acquisition in the growing age. All these factors influence the attainment of peak bone mass, a critical determinant of bone health and fracture risk in adulthood. Secondary osteoporosis is an important issue of clinical care in children with acute and chronic diseases. Systemic autoimmune disorders, like juvenile idiopathic arthritis, can affect the skeletal system, causing reduced bone mineral density and high risk of fragility fractures during childhood. In these patients, multiple factors contribute to reduce bone strength, including systemic inflammation with elevated cytokines, reduced physical activity, malabsorption and nutritional deficiency, inadequate daily calcium and vitamin D intake, use of glucocorticoids, poor growth and pubertal delay. In juvenile arthritis, osteoporosis is more prominent at the femoral neck and radius compared to the lumbar spine. Nevertheless, vertebral fractures are an important, often asymptomatic manifestation, especially in glucocorticoid-treated patients. A standardized diagnostic approach to the musculoskeletal system, including prophylaxis, therapy and follow up, is therefore mandatory in at risk children. Here we discuss the molecular mechanisms involved in skeletal homeostasis and the influence of inflammation and chronic disease on bone metabolism.
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Skotnikova, Yu V., A. N. Arkhangel’skaya, K. G. Gurevich, D. A. Pustovalov, and M. V. Ivkina. "Methods of physiotherapy in the treatment of obesity." Russian Journal of Physiotherapy, Balneology and Rehabilitation 19, no. 2 (December 27, 2020): 132–36. http://dx.doi.org/10.17816/1681-3456-2020-19-2-10.

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Currently, there is a significant increase in the prevalence of obesity among children and adolescents of the world population. Overweight and obesity are a global epidemic of humanity. In economically developed countries, including Russia, on average, every third inhabitant has a weight that exceeds the maximum allowed. Russia ranks 15th in the world in the prevalence of overweight and obesity among children and adolescents. Obesity is now considered as a chronic, relapsing disease associated with the development of a number of diseases that reduce life expectancy and reduce its quality. An important factor in demonstrating the urgency of the problem of child and adolescent obesity is its prognostically adverse effect on obesity in adulthood. The lack of targeted detection of overweight and obesity in children and adolescents in Russia accounts for its late diagnosis specialists. Complications of obesity affect the cardio vascular, reproductive, respiratory, nervous system, digestive organs, musculoskeletal system. In connection with the rise of obesity than the early detection of issues and preventive measures to prevent its further progression. Obesity in the early diagnosis and early treatment is a reversible condition. Important role in the treatment of obesity play a non-drug methods - diet, exercise stress, a variety of physical therapy, taking into account individual tolerance and comorbidity. Physiotherapy treatments have not only symptomatic but also the pathogenic effects, eliminating the primary metabolic and neuroendocrine disorders.
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Jurecka, Alicja, Maciej Papież, Paulina Skucińska, and Artur Gądek. "Evaluating the Effectiveness of Soft Tissue Therapy in the Treatment of Disorders and Postoperative Conditions of the Knee Joint—A Systematic Review." Journal of Clinical Medicine 10, no. 24 (December 18, 2021): 5944. http://dx.doi.org/10.3390/jcm10245944.

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The term “soft tissue therapy” (STT) refers to mechanical methods of treatment involving passive kneading, pressing and stretching of pathologically tense tissues in supporting the process of recovery after surgery or trauma to the musculoskeletal system. The objective of this study was to review current scientific reports evaluating the effectiveness of the use of STT in patients with diseases or after surgical procedures of the knee joint. A systematic search of the popular scientific databases PubMed, Scopus and Embase was performed from inception to 15 October 2021. Eight articles met eligibility criteria and were included in the review. Six papers were related to disorders of the knee joint, while the remaining two studies were related to dysfunctions associated with the conditions after surgical intervention. The findings presented confirmed the effectiveness of STT in orthopaedic patients who showed an increase in lower limb functional parameters. The research has shown that the use of various methods of STT has a significant impact on increasing muscle activity and flexibility as well as increasing the range of motion in the knee joint. The physiotherapeutic methods used had a significant impact on reducing pain and increasing physical function and quality of life. The techniques used reduced the time to descend stairs in patients with knee osteoarthritis. This review summarises the effectiveness of STT as an important form of treatment for orthopaedic patients with various knee joint dysfunctions.
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Dmitrenko, Olga, Andrey Chaplin, Anna Balbutskaya, Tamara Pkhakadze, and Sergey Alkhovsky. "In Silico Genome-Scale Analysis of Molecular Mechanisms Contributing to the Development of a Persistent Infection with Methicillin-Resistant Staphylococcus aureus (MRSA) ST239." International Journal of Molecular Sciences 23, no. 24 (December 16, 2022): 16086. http://dx.doi.org/10.3390/ijms232416086.

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The increasing frequency of isolation of methicillin-resistant Staphylococcus aureus (MRSA) limits the chances for the effective antibacterial therapy of staphylococcal diseases and results in the development of persistent infection such as bacteremia and osteomyelitis. The aim of this study was to identify features of the MRSAST239 0943-1505-2016 (SA943) genome that contribute to the formation of both acute and chronic musculoskeletal infections. The analysis was performed using comparative genomics data of the dominant epidemic S. aureus lineages, namely ST1, ST8, ST30, ST36, and ST239. The SA943 genome encodes proteins that provide resistance to the host’s immune system, suppress immunological memory, and form biofilms. The molecular mechanisms of adaptation responsible for the development of persistent infection were as follows: amino acid substitution in PBP2 and PBP2a, providing resistance to ceftaroline; loss of a large part of prophage DNA and restoration of the nucleotide sequence of beta-hemolysin, that greatly facilitates the escape of phagocytosed bacteria from the phagosome and formation of biofilms; dysfunction of the AgrA system due to the presence of psm-mec and several amino acid substitutions in the AgrC; partial deletion of the nucleotide sequence in genomic island vSAβ resulting in the loss of two proteases of Spl—operon; and deletion of SD repeats in the SdrE amino acid sequence.
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Lazetic, Aleksandar, Mirka Lukic-Sarkanovic, Dragan Savic, Oliver Dulic, Srdjan Radic, and Mirko Obradovic. "Knee osteoarthritis and arthroplasty of the knee joint." Medical review 69, suppl. 1 (2016): 41–45. http://dx.doi.org/10.2298/mpns16s1041l.

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According to the Public Health Institute of Vojvodina one of the main causes of morbidity, invalidity and absence from work in Vojvodina are musculoskeletal diseases. Osteoarthritis is a multifactorial joint disease, with catabolism and inflammation in its background. For radiological classification of knee osteoarthritis stage Kellgren-Lawrence scale is used. It consists of five levels, from stage ?0? to stage ?4?. The goal of osteoarthritis treatment is to reduce pain and muscle spasms, improve limb function, prevent joint contractures and train patients to function in everyday life and professional activities. The therapy is divided into conservative (medical and physical) and surgical. Arthroplasty is a surgical procedure that involves destruction of articular surfaces and replacement of degenerative joints with endoprostheses, which result in increased general and working ability. Modern endoprostheses enable a high success rate of the procedure. At the Department of Orthopedics and Traumatology, Clinical Center of Vojvodina in Novi Sad, the first knee aloarthroplasty was performed in 1989. Since then, more than 3000 knee aloarthro?plasties have been done. Clinical patient evaluation was obtained through subjective status, functional evaluation and use of scoring systems. More than 80% of patients had a good or a great score.
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43

Boroday, Aleksandra A., Dar’ya A. Tyapkina, Al’fiya R. Tyapayeva, Ol’ga N. Semenova, and Elizaveta A. Naumova. "Manifestations of a New Coronavirus Infection in Patients with Cardiovascular Diseases Undergoing Outpatient Treatment." NAUKA MOLODYKH (ERUDITIO JUVENIUM) 10, no. 1 (March 31, 2022): 33–44. http://dx.doi.org/10.23888/hmj202210133-44.

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BACKGROUND: SARS-CoV-2 virus, which induces COVID-19, not only affects the lungs, but also negatively affects the cardiovascular system, causing decompensation of the existing cardiovascular diseases (CVD). AIM: Тo find out the peculiarities of the course and treatment of the new coronavirus infection COVID-19 in patients with cardiovascular diseases (CVD). MATERIALS AND METHODS: A survey was conducted among patients with CVD undergoing outpatient treatment for COVID-19. A special questionnaire was developed containing 48 questions about the symptoms of COVID-19 and the prescribed therapy. The respondents were ill with a new coronavirus infection between August 2020 and January 2021. The survey involved 54 patients aged 43–82 years, among them 36 (66.7%) women and 18 (33.3%) men. Patients of age groups 61–70 years and 51–60 years prevailed (33.3% and 29.6%, respectively). The respondents had the following CVD: arterial hypertension — 54 (100%) and coronary heart disease (exertion angina) — 16 (29.6%). RESULTS. COVID-19 was manifested by cough — in 32 (59.3%) patients, shortness of breath — in 34 (63%). There was marked weakness (44 (81.5%)), limitation of physical activity (48 (88.9%)). Of the skin manifestations, patients described itching (14 (25.9%)). Myalgia was present in 40 (74.1%) patients and joint pain — in 36 (66.7%). Of the classic manifestations of COVID-19 infection, 34 (40.7%) and 22 (50%) patients had reduction or loss of olfaction and gustatory sensations. On the part of the gastrointestinal tract, the following symptoms were present: lack of appetite (6 (11.1%)), nausea (6 (11.1%)) and diarrhea (2 (3.7%)). Neurological manifestations of COVID-19, such as episodes of dizziness, disorientation in space and time, and feelings of fear and anxiety, were observed in 38 (70.6%) respondents. There were also unusual manifestations of the disease: increased blood pressure, decreased blood pressure, weakness in the legs, disorders in urination, ring-shaped granuloma, conjunctivitis, tickling in throat. Treatment: most patients with mild and moderate course of the disease took drugs that are not specified in the recommendations of the Ministry of Health of the Russian Federation for COVID-19. CONCLUSIONS: The majority of patients with CVD had manifestations of COVID-19 on the part of the respiratory, musculoskeletal systems, as well as neurological manifestations of the disease. Skin manifestations and manifestations on the part of the gastrointestinal tract were present only in a small part of the respondents.
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Savchuk, O., O. Korotkyi, and L. Коt. "Level of middle molecular peptides in the articular cartilage of rats under experimental osteoarthritis and administration of probiotic composition." Bulletin of Taras Shevchenko National University of Kyiv. Series: Biology, no. 87 (2021): 38–44. http://dx.doi.org/10.17721/1728.2748.2021.87.38-44.

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The question regarding clarification the mechanisms that link changes in the musculoskeletal system with changes in the microbiome, in recent few years has become particularly relevant. The investigation of the biological effect of probiotics on cartilage metabolism under osteoarthritis (OA) opens the perspectives for their use in complex therapy and prevention of joint pathology. The aim of the research was to analyze the quantitative and qualitative composition of the peptide component of the middle-mass molecules (MMM) of different fractions in the articular cartilage of rats with experimental OA under the introduction of multiprobiotic (PB) composition. The experiments were conducted on white male non-linear rats weighing 180-200 g. Experimental osteoarthritis in rats was induced by a single injection of sodium monoiodacetate (MIA; Sigma, USA) in the knee patellar ligament. The animals of therapeutic group received oral administration of live probiotic composition Multiprobiotic Simbiter® acidophilic concentrated ("O.D. Prolisok", Ukraine) at a dose of 140 mg/kg daily for 14 days. Euthanasia of animals was performed on the 30th day of the experiment. The level of MMM was assessed spectrophotometrically. Fractionation at the peptide level was performed using the method of chromatography, which is separated by size on Sephadex G 15 column. Our findings showed an increase in the MMM content of all studied fractions in cartilage tissue of rats with experimental OA and changes in the qualitative and quantitative composition of their the peptide component, that could indicate the development of endogenous intoxication, as a result of impaired cartilage metabolism, inflammation and destructive processes in the knee joint during the pathology. Administration to animals with MIA-induced OA PB composition had a favorable effect on the studied parameters, which was expressed in a decrease of MMM content and restored redistribution of the peptide pool of cartilage tissue. The obtained results provide grounds for further research aimed at studying the biological effect of PB on cartilage metabolism, which may contribute to the development of new strategies for the treatment and prevention of joint diseases.
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Yakovlev, E. V., S. A. Zhivolupov, E. N. Gnevyshev, and T. V. Vetrova. "General characteristics and features of the use of nonsteroidal anti-inflammatory drugs in the treatment of dorsopathies in clinical practice (literature review)." Meditsinskiy sovet = Medical Council, no. 23 (January 18, 2023): 68–77. http://dx.doi.org/10.21518/2079-701x-2022-16-23-68-77.

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Back pain ranks first among all non-communicable diseases in terms of the number of years of life lost due to poor health. At the same time, the choice of tactics for the treatment of dorsopathies presents certain difficulties, in particular, the choice of a nonsteroidal anti-inflammatory drug (NSAID), which depends on a number of factors. NSAIDs are effectively used in the treatment of musculoskeletal pain, but they have side effects, which determines the individual characteristics of their use. The article presents an overview of scientific data published in the sources MEDLINE, PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure, Clinical Trials.gov, services for the exchange of research information on the clinical practice of NSAID use. The general characteristics and side effects of NSAIDs in clinical practice are analyzed in order to choose an effective and safe trajectory of their use in the treatment of dorsopathies. In the acute period of dorsopathy, the therapeutic effect should be aimed primarily at reducing pain. At the same time, the use of NSAIDs is necessary and justified, should include a detailed assessment of side effects, duration of use, alternative trajectories of drug and non-drug treatment. Numerous side effects of NSAIDs from the gastrointestinal tract, liver, cardiovascular system, allergic reactions, congenital anomalies in the fetus when using NSAIDs during pregnancy and other undesirable consequences, make it necessary to take the maximum possible measures to minimize adverse reactions and long-term undesirable consequences for the patient. Combined therapeutic effects, including, along with the use of NSAIDs, physiotherapy, physical therapy, massage, reflexotherapy, optimization of motor activity, optimization of posture under static loads, the use of cognitive behavioral therapy methods, is optimal from the standpoint of risk stratification and the expected clinical effect in patients with dorsopathy.
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Czarkowska, Magdalena, Tomasz Saran, Anna Mazur, Andrzej Horoch, and Lech Panasiuk. "Impact of the comprehensive outpatient rehabilitation on reducing intensification of depressive symptoms in people over 60 years of age." Polish Journal of Public Health 128, no. 4 (December 1, 2018): 148–51. http://dx.doi.org/10.2478/pjph-2018-0029.

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Abstract Introduction. As a result of involution processes and diseases, changes occur in the human body, as a result of which, psychophysical fitness declines with age. Comprehensive rehabilitation is the way of improving and maintaining health condition, including, among others, the appropriate level of physical activity and the quality of affective functioning. This type of program was carried out as part of the Outpatient Healthcare Home (DDOM) at the Witold Chodźko Institute of Rural Health in Lublin. Aim. The objective of the present study was to assess the impact of comprehensive ambulatory rehabilitation, including tailored endurance training preceded by an ergospirometry test, on indicators demonstrating the level of involvement in daily physical activities and the severity of depressive symptoms of patients over 60 years of age receiving health services at DDOM. Material and methods. The study involved 60 seniors participating in the rehabilitation cycle implemented as part of the services provided to patients at DDOM of the Witold Chodźko Institute of Rural Health in Lublin. The tests were carried out in the test-retest model on the first and last day of the kinesiotherapy cycle. The tests were performed with use of International Physical Activity Questionnaire IPAQ and Geriatric Depression Scale GDS. The patient rehabilitation program included adapted systemic kinesiotherapy (endurance training with a load determined according to individual exercise capacity, as determined on the basis of the ergospirometry test) and local kinesiotherapy and physical therapy adapted to the needs resulting from the condition of the musculoskeletal system. Results. After the completion of the rehabilitation cycle we compared the tests carried out before it, and the patients received higher scores in the scales of IPAQ questionnaire for measuring weekly, intensive and mode-rate physical activity and time required for walking and were less likely to spend their time sitting or lying down. There were also lower scores of the respondents in GDS scale used to assess the severity of depressive symptoms. Conclusions. As a result of the rehabilitation program applied, DDOM patients simultaneously obtained the desired changes in the level of involvement in physical activity and minimization of the intensity of depressive symptoms.
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Kravtsova, Anna V., Volodymyr O. Pyatikop, and Yuliya G. Sergiyenko. "DUROPLASTY: REVIEW OF MATERIALS AND TECHNIQUES." Eastern Ukrainian Medical Journal 10, no. 1 (2022): 1–16. http://dx.doi.org/10.21272/eumj.2022;10(1):1-16.

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Introduction. Degenerative disc disease is one of the most common diseases of the musculoskeletal system, characterized by dystrophic changes in the intervertebral disc and vertebral bodies adjacent to it. The main symptoms of this disease are pain and sensory and motor disorders, which, according to various authors, occur in 50–80% of adults. The main objective of the study was to find and implement the optimal set of treatment measures for degenerative disc disease depending on the age of a patient. Materials and Methods. The medical records of inpatients who were treated in the Neurosurgical Department of the Sumy Regional Clinical Hospital in 2019–2020 were analyzed. The course of treatment of 93 patients (61 men and 32 women) was studied. The patients were divided into groups according to their age: young age (under 25) – 13 men and 8 women; middle age (under 60) – 24 men and 19 women; and elderly age (over 60 years) – 18 men and 11 women. The combined use of pathogenetically justified physiotherapeutic measures in the treatment complex is gaining more and more interest. Their distinctive features are physiologic nature, absence of allergic manifestations, the ability to influence most of the pathogenesis of the disease, and the organic combination with other therapeutic factors. Unfortunately, there is an increase in the incidence of temporary incapacitation and progressive course, which often leads to disability and significant financial costs associated with expensive modern methods of diagnosis, treatment, and further provision of employment to patients. The results of our study show that complex treatment including pathogenetic drug therapy, complex paravertebral block, therapeutic physical exercise, and physiotherapy treatment methods provides adequate recovery of spinal function regardless of dystrophic and degenerative changes severity and patient's age. Treatment of degenerative disc disease should be comprehensive and directed at the various symptoms and links of the pathological process.
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Potapov, Oleksandr O., Oleksiy P. Kmyta, Oleksandr O. Tsyndrenko, Maryna V. Pavlova, and Dmytro A. Zaporozhets. "COMPREHENSIVE TREATMENT OF DISCOPATHIES OF THE LUMBAR SPINE." Eastern Ukrainian Medical Journal 9, no. 4 (2021): 318–24. http://dx.doi.org/10.21272/eumj.2021;9(4):318-324.

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Introduction. Degenerative disc disease is one of the most common diseases of the musculoskeletal system, characterized by dystrophic changes in the intervertebral disc and vertebral bodies adjacent to it. The main symptoms of this disease are pain and sensory and motor disorders, which, according to various authors, occur in 50–80% of adults. The main objective of the study was to find and implement the optimal set of treatment measures for degenerative disc disease depending on the age of a patient. Materials and Methods. The medical records of inpatients who were treated in the Neurosurgical Department of the Sumy Regional Clinical Hospital in 2019–2020 were analyzed. The course of treatment of 93 patients (61 men and 32 women) was studied. The patients were divided into groups according to their age: young age (under 25) – 13 men and 8 women; middle age (under 60) – 24 men and 19 women; and elderly age (over 60 years) – 18 men and 11 women. The combined use of pathogenetically justified physiotherapeutic measures in the treatment complex is gaining more and more interest. Their distinctive features are physiologic nature, absence of allergic manifestations, the ability to influence most of the pathogenesis of the disease, and the organic combination with other therapeutic factors. Unfortunately, there is an increase in the incidence of temporary incapacitation and progressive course, which often leads to disability and significant financial costs associated with expensive modern methods of diagnosis, treatment, and further provision of employment to patients. The results of our study show that complex treatment including pathogenetic drug therapy, complex paravertebral block, therapeutic physical exercise, and physiotherapy treatment methods provides adequate recovery of spinal function regardless of dystrophic and degenerative changes severity and patient's age. Treatment of degenerative disc disease should be comprehensive and directed at the various symptoms and links of the pathological process.
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Hertsyk, Andrii. "System resources of physical rehabilitation / physical therapy in musculoskeletal disorders." Слобожанський науково-спортивний вісник 5, no. 55 (October 31, 2016): 22–27. http://dx.doi.org/10.15391/snsv.2016-5.004.

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Sultan, Nasir, Kiran Khushnood, and Waqar Ahmed Awan. "A Lesson / An Eye Opener." Rehabilitation Journal 6, no. 1 (March 31, 2022): 268–69. http://dx.doi.org/10.52567/trj.v6i01.149.

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The pandemic of Coronavirus disease 2019 (COVID-19) has led to serious implications throughout the globe ranging from finance, education, social support to health. There is hardly any aspect left untouched by this fatality. It has also opened our eyes about unequal and unjust distribution of resources among the world where the deprived have seen the worse scenarios. The developed nations tried to cope this situation with their assets while the rest have either suffered or have emerged even stronger. The major burden was definitely on the health services delivery and provision, where the scares means from equipment to space and man power have all played their role. The pandemic has opened the eyes of health policy makers and service providers who were living in deception and have never been ready for certain contagion. We have come to know that the medical services are never enough to deal with similar situation. COVID-19 has taught us the skill of how to be prepared and fight in a worse situation but unfortunately, we have learned this after losing many precious lives. The changes in healthcare practices have also been modified. The infection control (IC) system which should have been a focus prior became a highlight after pandemic. The IC practices in hospitals (public and private sector) were not sufficient and adherence to them wasn’t observed either. Even the majority of services providers and heath care professionals weren’t aware of use of personal protective equipment (PPE); their use and sequences of donning and doffing, except for those working in intensive care units and isolation areas. Thanks to COVID-19 who taught us to be familiar with these things whether their use is un-common. COVID-19 has also been a guide for people in rehabilitation who are prime part of recovery from all illnesses including this pandemic. COVID-19 was found to be a cause of multiple complications i.e. pulmonary, cardiac, neurological, musculoskeletal, psychological and social. Attention was also diverted to recovery in all the mentioned aspects which led to provision and improvements in tertiary care setups with focus on rehabilitation as a mode of full recovery. The stakeholders have started to be more focused on improving the mental and physical aspects of disease along with the physiological. The rehabilitation and physical therapy services have not been spared from the pandemic. Where the physical therapy professionals were not ready and well trained to deal with contagious diseases and safety measures it put us in a bigger challenge. Many clinics and hospitals had scares availability of personnel protective equipment (PPE) which also lead to seriousness of situation. As for provision of physical therapy care direct contact with patients cannot be limited, and lack of knowledge on unavailability of PPE could put therapist’s or the patient’s life in danger. Covid-19 opened the eyes and importance of teaching safety measures and donning and doffing of PPEs was learned with appropriate sequence. Although the well-organized hospitals were also working as per global standard protocols had least difficulty dealing with such issues. The physical therapists are trained to deal with such emergencies and critical situations but not being exposed to a pandemic and emergency like this has made the suppression of such reflexes in practice. The therapist learned to manage patients with optimum precautions making sure that the quality of care is not compromised. Several tele-rehabilitation models have also been develop and practiced to encounter the issue.1, 2 Hence we would take COVID-19 as an eye opener and as taught to be fair in the division of global resources and be prepared for a disaster that doesn’t discriminate among developed and undeveloped nations. The efficient use of services and being aware of emergency and safe healthcare practices can save us from unpredictable disasters like COVID-19.
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