Journal articles on the topic 'Musculoskeletal system Diseases Diagnosis'
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1
F. Fasanelo Gomes, Luanna, and Stefano C. Filippo Hagen. "Ultrasonography diagnosis of joint diseases in dogs – review." Clínica Veterinária XXIV, no. 139 (March 1, 2019): 54–65. http://dx.doi.org/10.46958/rcv.2019.xxiv.n.139.p.54-65.
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Ultrasonography is not frequently used in the evaluation of the musculoskeletal system of dogs. During the last three decades this imaging technique has been shown to be valuable in the diagnosis and monitoring the musculoskeletal disorders of human patients. Ultrasonography allows recognitions of different anatomical joint structures and enables detection of lesions in tendons, ligaments, joint capsule, cartilage, meniscus and bone surfaces. The diagnostic value of the technique is highly operator-dependent, and can be influenced by the difficult to access to some anatomical structures. In spite of its limitations, the availability and low cost of the ultrasonography can make it an important tool in the assessment of musculoskeletal disorders in dogs.
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Tang, Xiaoyi, Mengxin Zhao, Wei Li, and Jiaqi Zhao. "Nanoscale Contrast Agents for Ultrasound Imaging of Musculoskeletal System." Diagnostics 12, no. 11 (October 25, 2022): 2582. http://dx.doi.org/10.3390/diagnostics12112582.
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Musculoskeletal ultrasound (MSKUS) has been recognized as an important method for the evaluation of diseases of the musculoskeletal system, and contrast-enhanced ultrasound (CEUS) technology is becoming an important branch of it. The development of novel materials and tiny nano-formulations has further expanded ultrasound contrast agents (UCAs) into the field of nanotechnology. Over the years, nanoscale contrast agents have been found to play an unexpected role in the integration of precise imaging for diagnosis and treatment of numerous diseases. It has been demonstrated that nanoscale UCAs (nUCAs) have advantages in imaging over conventional contrast agents, including superior biocompatibility, serum stability, and longer lifetime. The potential value of nUCAs in the musculoskeletal system is that they provide more reliable and clinically valuable guidance for the diagnosis, treatment, and follow-up of related diseases. The frontier of advances in nUCAs, their applications, and insights in MSKUS are reviewed in this paper.
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Matveeva, Natalia Yu, Ekaterina V. Makarova, Nikolay A. Eskin, and Tatiana V. Sokolova. "Consequences of COVID-19 for the musculoskeletal and peripheral nervous systems. Diagnosis of complications (literature review)." N.N. Priorov Journal of Traumatology and Orthopedics 29, no. 1 (October 4, 2022): 65–77. http://dx.doi.org/10.17816/vto105957.
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COVID-19 disease does not only lead to impaired respiratory function. Post-COVID complications are multiple with the involvement of many body systems, including the musculoskeletal system and the peripheral nervous system. Diseases of the musculoskeletal system include myalgia, myositis, rhabdomyolysis, acute arthralgia, arthritis, bone osteoporosis. Damage to the peripheral nervous system caused by coronavirus infection includes plexopathy due to lying down, poly-neuropathy, GuillainBarre syndrome. This descriptive literature review discusses the effects of COVID-19 on the musculoskeletal system and the peripheral nervous system of patients. Data are presented on the use of diagnostic tools such as computed tomography, magnetic resonance imaging, and ultrasound scans to detect pathology.
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Vinderlikh, M. E., and N. B. Schekolova. "Use of thermal imager in complex diagnosis and treatment of musculoskeletal system diseases: literature review." Perm Medical Journal 37, no. 4 (November 6, 2020): 54–61. http://dx.doi.org/10.17816/pmj37454-61.
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The experience of using thermal imager in diagnosis and treatment of musculoskeletal system diseases based on review of domestic and foreign literature is presented in the paper. Bibliographical method was applied. A short history of using thermovision in foreign and domestic practice is considered, the problem aspects of the offered technology are accentuated, the use of thermal imager in diagnosis and treatment of musculoskeletal system diseases is analyzed. The possible prospects for development of thermovision in domestic medical practice are determined.
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Kozhevnikov, Aleksei Nikolaevich, Nina Anatolievna Pozdeeva, Mikhail Aleksandrovich Konev, Vladimir Vasilievich Selizov, Evgenii Vladimirovich Prokopovich, Maksim Sergeevich Nikitin, Aleksei Vitalievich Moskalenko, and Konstantin Alexandrovich Afonichev. "JUVENILE ARTHRITIS: CLINICAL MANIFESTATIONS AND DIFFERENTIAL DIAGNOSIS AND DIFFERENTIAL DIAGNOSIS." Pediatric Traumatology, Orthopaedics and Reconstructive Surgery 2, no. 4 (December 15, 2014): 66–73. http://dx.doi.org/10.17816/ptors2466-73.
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The diagnosis and treatment of inflammatory joint diseases is the pressing problem of pediatric rheumatology and orthopedics. Juvenile arthritis is the most frequent chronic inflammatory disease of the musculoskeletal system in children and adolescents. Still juvenile arthritis is often misdiagnosed. The article provides current knowledge on juvenile arthritis, its clinical manifestations, as well as diagnostic and treatment strategies, and differential diagnosis.
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Palczewski, Piotr. "Imaging diagnosis of osteoarthritis." Polish Journal of Sports Medicine 37, no. 2 (June 30, 2021): 103–15. http://dx.doi.org/10.5604/01.3001.0015.0449.
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Osteoarthritis (OA) is currently one of the most common diseases of the musculoskeletal system in the population. Establishing a proper diagnosis usually requires a lot of imaging examinations. The aim of the article is to present the diagnostic possibilities of individual tests and to analyze their place in the modern diagnosis of this common disease.
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Piróg, Katarzyna A., and Michael D. Briggs. "Skeletal Dysplasias Associated with Mild Myopathy—A Clinical and Molecular Review." Journal of Biomedicine and Biotechnology 2010 (2010): 1–13. http://dx.doi.org/10.1155/2010/686457.
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Musculoskeletal system is a complex assembly of tissues which acts as scaffold for the body and enables locomotion. It is often overlooked that different components of this system may biomechanically interact and affect each other. Skeletal dysplasias are diseases predominantly affecting the development of the osseous skeleton. However, in some cases skeletal dysplasia patients are referred to neuromuscular clinics prior to the correct skeletal diagnosis. The muscular complications seen in these cases are usually mild and may stem directly from the muscle defect and/or from the altered interactions between the individual components of the musculoskeletal system. A correct early diagnosis may enable better management of the patients and a better quality of life. This paper attempts to summarise the different components of the musculoskeletal system which are affected in skeletal dysplasias and lists several interesting examples of such diseases in order to enable better understanding of the complexity of human musculoskeletal system.
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Abdrakhmanova, R. Sh. "Current problems of diagnosis and treatment of rheumatic diseases." Kazan medical journal 68, no. 1 (February 15, 1987): 5–9. http://dx.doi.org/10.17816/kazmj95887.
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In recent years, rheumatology has clearly defined itself as an independent field of medicine, which studies a large group of diseases of the musculoskeletal system and connective tissue with the most characteristic inflammatory or degenerative joint involvement. Despite the advances in treatment, rheumatic diseases remain an extremely urgent problem of medical science. Their significant prevalence, frequent development in persons of mature working age, a clear tendency to a chronic course also determine the socio-economic significance of these diseases.
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Drozd, Małgorzata, Adrianna Gorecka, Bartłomiej Zaremba, and Violetta Opoka-Winiarska. "Differential diagnosis in children with musculoskeletal pain in Emergency Department." Journal of Education, Health and Sport 12, no. 11 (October 28, 2022): 143–53. http://dx.doi.org/10.12775/jehs.2022.12.11.019.
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Objective: The study was aimed to analyze the diagnostic approach to a child with a non-traumatic musculoskeletal pain registered in the pediatric Hospital Emergency Department (HED). Since the pandemic COVID-19 affects patient health and the healthcare system, we also evaluated the impact of pandemic on type of musculoskeletal symptoms.
Study design: A retrospective cross-sectional study was conducted by statistical analysis of data of patients with non-traumatic musculoskeletal pain registered in HED between January 2018 and December 2020. Data of patients referred and not referred to hospital ward and admitted to HED before and during COVID-19 pandemic have been compared.
Results: Majority of patients presented acute, non-trauma related, single-site pain, usually localized in the hip, the knee and the spine. 21,49% of patients were referred to a hospital ward, usually rheumatological, neurological or orthopedic. Final diagnoses in almost ¾ patients belong to the group of musculoskeletal system and connective tissue disorders. During the pandemic significantly less patients with musculoskeletal pain reported to our HED. The duration of symptoms before admission was not significantly longer than in previous years, but the problem in children and the impact of the pandemic on the musculoskeletal system in children is complex.
Conclusions: Our study provides detailed information on patterns of pediatric musculoskeletal consultations in HED. A positive history of trauma preceding musculoskeletal pain in a child may only be accidentally related to the final cause. Musculoskeletal pain can be also a symptom of a lot of various systemic conditions, not only diseases of the musculoskeletal system. The still ongoing COVID-19 pandemic may require changes in the organization of the HED. We believe that the presented results can help in organizing and planning care in pediatric HEDs, develop diagnostic algorithms and training for HED staff.
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Shundryk, Marina A., Iryna Y. Marchenko, Iryna M. Tkachenko, Viktor V. Boiko, Valeriy Y. Marchenko, and Olga V. Sheshukova. "THE VALUE OF DENTAL EXAMINATION FOR EARLY DIAGNOSIS OF THE MUSCULOSKELETAL SYSTEM DISEASES." Wiadomości Lekarskie 73, no. 9 (2020): 2017–19. http://dx.doi.org/10.36740/wlek202009223.
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The aim: The purpose of the study was to determine the correspondence between the location of the tongue median line and the degree of distortion of the vertebral column at different levels in children with scoliosis. Materials and methods: Totally 56 children (30 girls, 26 boys) aged 11-14 years were examined, with a duration of musculoskeletal disorders 1-3 years. For each participant an oral cavity examination was performed, the position of the middle line of the tongue was determined. X-ray images of vertebral column of the patients from investigated groups were analyzed. Results: In the group with 1year duration of the disease 25.02% patients had a violation of the medial line of the tongue, in the group with 2 years of duration of the disease - 65,52% participants had the deviation of the medial line of the tongue, in the group with 3 years of duration of the disease 86.66% of patients had the deviation of the medial line of the tongue. Conclusions: This research allows us to recommend paying attention not only to the size, color, state of the papillae of the tongue, but also to the position of the middle line, which distortion may significate the deviation of the vertebral column in different portions.
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Johnson, Justine, Connie Austin, and Gert Breur. "Incidence of Canine Appendicular Musculoskeletal Disorders in 16 Veterinary Teaching Hospitals from 1980 through 1989." Veterinary and Comparative Orthopaedics and Traumatology 07, no. 02 (1994): 56–69. http://dx.doi.org/10.1055/s-0038-1633097.
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SummaryThe goal of this study was to determine the incidence of musculoskeletal disorders in a large canine population. Patient information was obtained from clinical cases contributed to the Veterinary Medical Data Base (VMDB) by 16 veterinary teaching hospitals during the ten year period of 1980 through 1989. The relative contribution of bone diseases, joint diseases, and muscle-tendon-unit diseases was determined, and the incidence of each musculoskeletal disease reported.Nearly 24% of all patients in the source population had been affected by a disorder of the musculoskeletal system, and over 70% of those diagnoses involved appendicular structures. Diseases of joints, ligaments, and related structures contributed more cases (47%) to this study than diseases of bones (39%) or muscle-tendon-units (14%). Fractures made up the largest disease category, with pelvic fractures most common, followed by femoral fractures, and fractures of the radius and/or ulna. Joint instability and degenerative joint dis-ease were also common diagnosis categories, affecting primarily the hip and stifle joints. Common specific dis-ease entities included hip dysplasia, cruciate ligament rupture, traumatic hip luxation and patellar luxation.In this study we provided a comprehensive analysis of the canine musculoskeletal system. The relative importance of joint disorders compared to those of bones and muscle-tendon-units was illustrated. The incidence of most of the disorders described in this report had not been well documented previously.Patient information was obtained from the clinical cases of 16 veterinary teaching hospitals during a 10-year period. The number of dogs with musculoskeletal disorders was determined. The absolute and relative contribution of bone diseases, joint diseases, and muscle-tendon-unit diseases is reported as well as the incidence of the specific disease entities affecting the canine appendicular musculoskeletal system.
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Kamosko, Mikhail Mikhailovich, and Mahmoud Stanislavovich Poznovich. "Radiological diagnosis of hip joint abnormalities in children." Pediatric Traumatology, Orthopaedics and Reconstructive Surgery 3, no. 2 (June 15, 2015): 32–41. http://dx.doi.org/10.17816/ptors3232-41.
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Abnormalities of the hip joint in children covers a wide range of diseases, including both congenital and acquired ones. Hip dysplasia, Legg-Calve-Perthes disease and juvenile slipped capital femoral epiphysis account for up to 25 % of all diseases of the musculoskeletal system in pediatric patients. Early diagnosis of these disorders and timely treatment are of paramount importance in the prevention of childhood disability.
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Cadner, P., and E. R. Mattis. "Some principles of organizing orthopedic care in Germany." N.N. Priorov Journal of Traumatology and Orthopedics 2, no. 1-2 (December 28, 1995): 79–82. http://dx.doi.org/10.17816/vto99608.
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Orthopedic care in Germany provides for the prevention, diagnosis and treatment of congenital and acquired functional disorders, diseases, injuries and consequences of injuries of the musculoskeletal system, as well as rehabilitation treatment (rehabilitation) of patients with pathology of the musculoskeletal system, i.e. in its content, orthopedics as a discipline in Germany corresponds to traumatology and orthopedics in Russia.
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Quin, Kai, and Hareth M. Madhoun. "Ultrasound as a Biomarker in Rheumatic Diseases." Diagnostics 10, no. 11 (November 10, 2020): 933. http://dx.doi.org/10.3390/diagnostics10110933.
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Rheumatic diseases are a heterogeneous group of disorders which often affect the musculoskeletal system. Given the lack of definitive testing, there are limited diagnostic tools at clinicians’ disposal. Over the recent decades, ultrasonography has gained widespread use within rheumatology due to its accessibility, safety, and relatively low cost. This review describes the clinical utility of ultrasound as a biomarker in the diagnosis and management of several rheumatic diseases.
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O. V. Hlubochenko, V. H. Hlubochenko, K. O. Bobkovych, L. V. Mykulets, and N. B. Reshetilova. "CLINICAL-ANATOMICAL AND ULTRASOUND PARALLELS IN THE DIAGNOSIS OF MUSCULO-SKELETAL SYSTEM DISEASES (LITERATURE REVIEW)." Clinical anatomy and operative surgery 15, no. 4 (November 24, 2016): 96–102. http://dx.doi.org/10.24061/1727-0847.15.4.2016.107.
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The article presents a review of literature dealing with clinical application of ultrasound method in rheumatology. Clinical- anatomical and ultrasound parallels in the diagnosis of various diseases of the musculoskeletal system are analyzed. Advantages and disadvantages of ultrasound imaging method in the examination of joints, muscles, ligaments and soft tissues are presented. The modern data of the ultrasound changes in rheumatoid arthritis, psoriatic arthritis, reactive arthritis, rheumatic polymyalgia are provided, diagnostic evaluation of this method in rheumatic diseases and comparative analysis with other methods of examination are presented.
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Fedotova, A. S., N. N. Molitvoslovova, L. I. Alekseeva, L. Ya Rozhinskaya, A. S. Fedotova, N. N. Molitvoslovova, L. I. Alexeeva, and L. Y. Rozhinskaya. "CONDITION OF THE MUSCULOSKELETAL SYSTEM IN PATIENTSWITH ACROMEGALY." Osteoporosis and Bone Diseases 13, no. 1 (April 15, 2010): 19–27. http://dx.doi.org/10.14341/osteo2010119-27.
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Despite the relatively low incidence of acromegaly (60-70 cases per I million inhabitants), this disease has a special place among the heterogeneous group of diseases that lead to the defeat of the locomotor apparatus. The slow growth of the clinical manifestations of acromegaly and as a consequence, late diagnosis, the cause of early disability and premature death of patients. In order to improve the quality of life and social adaptation of patients to date is an obvious need to identify groups of patients with acromegaly, requiring additional therapy for osteoporosis and osteoarthritis. We performed the search in bibliographic bases MEDLINE and Cochrane Collaboration from 2000 on 2009. Key words were the following: acromegaly, acromegaly and arthropathy, osteoporosis and acromegaly, the bone mineral density and acromegaly, fractures and acromegaly. In this article the data about role of risk factors for the defeat ofosteoarticular apparatus, the dynamics of the articular syndrome and the state of bone tissue in acromegaly.
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Svetlakova, M. V., and L. E. Morozova. "Hydrorehabilitation of women aged 55-60 with a diagnosis of hernia of the lumbar spine." Scientific and educational basics in physical culture and sports, no. 2 (November 21, 2021): 49–55. http://dx.doi.org/10.57006/2782-3245-2022-6-2-49-55.
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Relevance. Vertebroneurological disorders are the most common chronic diseases. Lumbar osteochondrosis is one of the most common diseases of the peripheral nervous system, has a tendency to relapses, often causing temporary disability. At the present stage of the development of medicine, physical therapy occupies a prominent place in the process of rehabilitation with diseases of the musculoskeletal system.Purpose. Improvement of the functional state of the musculoskeletal system and cardiovascular system in 55-60-year-old women with lumbar spine hernias.Methodology and organization of the research. There were 7 women under observation, aged 55-60 years with a diagnosis of "hernia of the lumbar spine", at the polyclinic stage. According to the previous examination, all patients had characteristic complaints of intermittent pain syndrome of moderate and weak intensity. There were also complaints of rapid fatigue.The results of the research. The study of the general condition of the patients by means of the Roland-Morris questionnaire indicated the existing disorders of the patients' vital activity (11.6 points). When comparing repeated results, a decrease in the level of violations to 6.3 points was reliably noted.Conclusions. Comparison of these functional samples showed reliable dynamics of the results.
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Vilanova, Joan C., Roberto García-Figueiras, Antonio Luna, Sandra Baleato-González, Xavier Tomás, and José A. Narváez. "Update on Whole-body MRI in Musculoskeletal Applications." Seminars in Musculoskeletal Radiology 23, no. 03 (June 2019): 312–23. http://dx.doi.org/10.1055/s-0039-1685540.
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AbstractWhole-body magnetic resonance imaging (WB-MRI) is a powerful tool increasingly used to assess oncologic and nononcologic diseases. WB-MRI provides information about diffuse multifocal pathologies with excellent anatomical definition through high soft tissue contrast and spatial resolution as well as valuable functional information from diffusion-weighted images. In addition to its roles in establishing the diagnosis and assessing the extent and severity of disease, WB-MRI is also useful for monitoring the response to treatment for malignant and benign systemic diseases affecting the musculoskeletal system. This article reviews and updates the applications of WB-MRI in current practice, discussing the role of this helpful tool in various conditions involving the musculoskeletal system including bone metastases, hematologic cancers, inflammatory processes, infections, and multisystemic-multifocal bone, nerve, vascular, and muscle/soft tissue disorders, as well as other idiopathic conditions.
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Demmler, Joanne C., Mark D. Atkinson, Emma J. Reinhold, Ernest Choy, Ronan A. Lyons, and Sinead T. Brophy. "Diagnosed prevalence of Ehlers-Danlos syndrome and hypermobility spectrum disorder in Wales, UK: a national electronic cohort study and case–control comparison." BMJ Open 9, no. 11 (November 2019): e031365. http://dx.doi.org/10.1136/bmjopen-2019-031365.
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ObjectivesTo describe the epidemiology of diagnosed hypermobility spectrum disorder (HSD) and Ehlers-Danlos syndromes (EDS) using linked electronic medical records. To examine whether these conditions remain rare and primarily affect the musculoskeletal system.DesignNationwide linked electronic cohort and nested case–control study.SettingRoutinely collected data from primary care and hospital admissions in Wales, UK.ParticipantsPeople within the primary care or hospital data systems with a coded diagnosis of EDS or joint hypermobility syndrome (JHS) between 1 July 1990 and 30 June 2017.Main outcome measuresCombined prevalence of JHS and EDS in Wales. Additional diagnosis and prescription data in those diagnosed with EDS or JHS compared with matched controls.ResultsWe found 6021 individuals (men: 30%, women: 70%) with a diagnostic code of either EDS or JHS. This gives a diagnosed point prevalence of 194.2 per 100 000 in 2016/2017 or roughly 10 cases in a practice of 5000 patients. There was a pronounced gender difference of 8.5 years (95% CI: 7.70 to 9.22) in the mean age at diagnosis. EDS or JHS was not only associated with high odds for other musculoskeletal diagnoses and drug prescriptions but also with significantly higher odds of a diagnosis in other disease categories (eg, mental health, nervous and digestive systems) and higher odds of a prescription in most disease categories (eg, gastrointestinal and cardiovascular drugs) within the 12 months before and after the first recorded diagnosis.ConclusionsEDS and JHS (since March 2017 classified as EDS or HSD) have historically been considered rare diseases only affecting the musculoskeletal system and soft tissues. These data demonstrate that both these assertions should be reconsidered.
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Kurnikova, A. A., Yu P. Potekhina, A. A. Filatov, E. A. Kalinina, and E. S. Pervushkin. "The role of the musculoskeletal system in maintaining postural balance: literature review." Russian Osteopathic Journal, no. 3-4 (February 11, 2020): 135–49. http://dx.doi.org/10.32885/2220-0975-2019-3-4-135-149.
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The article aims to consider the role of the musculoskeletal system in maintaining the postural balance. It describes two postural strategies (ankle one and hip one). The postural balance is assessed taking into account the «cone of economy». The article considers segmental anatomical and physiological characteristics of the spinal column and joints of the lower extremities participating in maintaining the vertical posture. It also shows the possibilities of non-radiological assessment methods of balance in the diagnosis and correction of postural disorders and diseases of the joints and spine.
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Makungu, Modesta. "Anatomy of the Red Panda (Ailurus fulgens)." Journal of Biology and Life Science 10, no. 1 (October 24, 2018): 13. http://dx.doi.org/10.5296/jbls.v10i1.13677.
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The red panda (Ailurus fulgens) is an endangered species primarily distributed in the southern China and Himalayas. It lives in mountain forests with bamboo understory. This review outlines the normal anatomy of the red panda in terms of its musculoskeletal system, respiratory system, circulatory system, digestive system and urogenital system. Knowledge of the normal anatomy of individual animal species is important for species identification and accurate interpretation and diagnosis of diseases.
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Quereza e Silva Faria, T., S. Ribeiro, G. Araújo, J. Simão, A. Vieira, L. Praciano, and A. P. Narciso Resk Maklouf. "AB1204 MUSCULOSKELETAL MANIFESTATIONS IN PATIENTS WITH ENDOCRINE DISORDERS IN AN AMAZON OUTPATIENT CLINIC." Annals of the Rheumatic Diseases 81, Suppl 1 (May 23, 2022): 1716.2–1717. http://dx.doi.org/10.1136/annrheumdis-2022-eular.3305.
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BackgroundChronic pain is frequently associated with these conditions and is an important cause of care in the health service. This pain is among the main manifestations of the musculoskeletal system, and 40% of individuals can manifest this type of pain at some point in their lives. That is why it is important to have doctors prepared to make an adequate approach to the symptomatology and especially to the underlying diseases. Rheumatic manifestations are part of the manifestation of systemic diseases, in which include diseases of the endocrine system, which can mimic rheumatic conditions. Despite the ignorance of some, endocrine diseases are underlying diseases linked to musculoskeletal manifestations. Thus, secondary arthropathies of non-rheumatologic origin or osteoarticular complaints that simulate or show rheumatic diseases can be found in patients with endocrine diseases during their evolution or in the initial phase along with other systemic symptoms. Based on this concept, we carried out the follow-up and evaluation of musculoskeletal manifestations presented by patients with endocrine disorders in a tertiary health service.ObjectivesThe aim of this study is to characterize the musculoskeletal manifestations in patients with endocrine diseases: type 1 and type 2 Diabetes Mellitus; hypothyroidism; hyperthyroidism and pituitary diseases and to clinically classify the patients based on physical examination and imaging findings.MethodsA cross-sectional and descriptive study, where clinical screening was performed at the endocrinology outpatient clinic, in which patients with musculoskeletal complaints were identified. These patients were referred for evaluation with a rheumatologist with clinical, laboratory and imaging investigation for the diagnosis of rheumatic disease. A questionnaire with epidemiological and clinical data was applied.ResultsTo date, 466 patients diagnosed with endocrine diseases have been interviewed, 53.4 ± 14.7 years old, 371 (79.6%) were female and 95 (20.4%) were male. Of the patients interviewed, 326 (70.1%) reported musculoskeletal pain. In relation to endocrine diseases, the most frequent one was type 2 DM with 212 patients (45.5%), and 77.25% of these people have chronic musculoskeletal pain, most of them 5 to 7 times a week, showing an intrinsic character of this disease with pain complaints from a great part of this population. The prevalence of 27.3% of hypothyroidism, 10.7% of DM type 1, 7.1% of hyperthyroidism, and less expressive amounts of other endocrine diseases such as acromegaly (1.7%), giantism (0.4%), and the like were also identified. About 59.6% of those who have pains are not followed up in the rheumatology service, 41.3% of these have already indicated these pains to their endocrinologist, however they did not have their complaint properly signaled. Of those interviewed, 94 (37.5%) take antihypertensives and 32.7% oral anti-diabetics. The most commonly found diagnoses in rheumatic diseases: Rheumatoid Arthritis (39%); Osteoarthritis 22.9% and Fibromyalgia 20%; Osteoporosis 19%, Tendinitis calcaria, Psoriatic Arthritis and GOTA with 5.7%. The main joints affected were: Hands (54.4%); Knees (45.3%) and feet (41.8%).ConclusionOur research with pre liminal results has demonstrated the mutuality between endocrine diseases and musculoskeletal manifestations and, therefore, that rheumatologic diagnoses are increasingly frequent in this population. The high prevalence of these symptoms secondary to endocrine diseases raises serious questions to improve the quality of life of these patients, and also to increase the number of investigations in this field, because the pathophysiological mechanisms of this association are not well elucidated and, from there, to expand this information to professionals who may not be aware of this relationship.References[1]FERREIRA GD. Prevalence and associated factors of back pain in adults from southern Brazil: population-based study. Rev Bras Fisioter. 2011;15(1):31-6.Disclosure of InterestsNone declared
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Maduakonam, Dim Edwin, Lam Ying Lee, Ho Wai Yip Kenneth, Yau Ching Hin Raymond, and WH Shek Tony. "Tuberculous osteomyelitis of the proximal femur masquerading as bone secondary: A case report." Journal of Orthopaedics, Trauma and Rehabilitation 27, no. 1 (March 24, 2020): 72–76. http://dx.doi.org/10.1177/2210491720907492.
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Tuberculosis is a mycobacterial infection, but it can mimic many diseases including diseases of the musculoskeletal system. The need to consider it as a differential diagnosis of musculoskeletal tumours and tumour-like conditions cannot be overemphasized. The opinions of some, that tuberculosis is a disease of the undeveloped world, can no longer be sustained especially in the presence of immunodeficiency disorders, including HIV/AIDS, which have a worldwide prevalence. Traditionally, literature evidence shows that tuberculosis can mimic quite a number of diseases, including cancers. This has been found to be true, even in some technologically advanced countries. We present a case of hepatocellular cancer patient incidentally found to have concomitant hepatic tuberculosis who complained of bone lesion, with clinico-radiologic features of metastasis, but which turned out to be a tuberculous infection of the bone.
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Seed, Lydia, Natasha G, Sarah Prentice, and Prathiba Chandershekar. "Early diagnosis of Malan syndrome in an infant presenting with macrocephaly." BMJ Case Reports 15, no. 11 (November 2022): e249391. http://dx.doi.org/10.1136/bcr-2022-249391.
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We present an infant with persistent macrocephaly and developmental delay. There is a wide range of differential diagnoses for this presentation, including many rare genetic conditions. Here, a diagnosis of Malan syndrome was made—a rare overgrowth syndrome caused by haploinsufficiency ofNFIXand features affecting the neurological and musculoskeletal systems. Improvements in genomic medicine technologies and clinical services have revolutionised the way clinicians diagnose rare diseases. We highlight the importance of early genetic testing, particularly if there are red flag features such as developmental delay, and the need for a coordinated strategy to improve the management of rare diseases like Malan syndrome.
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Beers-Tas, Marian van, Markus MJ Nielen, Jos W. R. Twisk, Joke Korevaar, and D. van Schaardenburg. "Increased primary care use for musculoskeletal symptoms, infections and comorbidities in the years before the diagnosis of inflammatory arthritis." RMD Open 6, no. 2 (July 2020): e001163. http://dx.doi.org/10.1136/rmdopen-2019-001163.
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ObjectivesLittle is known about relevant events in the at-risk phase of rheumatoid arthritis before the development of clinically apparent inflammatory arthritis (IA). The present study assessed musculoskeletal symptoms, infections and comorbidity in future IA patients.MethodsIn a nested case–control study using electronic health records of general practitioners, the frequency and timing of 192 symptoms or diseases were evaluated before a diagnosis of IA, using the International Classification of Primary Care coding system. Cases were 2314 adults with a new diagnosis IA between 2012 and 2016; controls were matched 1:2. The frequency of primary care visits was compared using logistic regression.ResultsThe frequency of visits for musculoskeletal symptoms (mostly of shoulders, wrists, fingers and knees) and carpal tunnel syndrome was significantly higher in IA patients vs controls within the final 1.5 years before diagnosis, with ORs of 3.2 (95% CI 2.8 to 3.5), 2.8 (95% CI 2.5 to 3.1) and 2.5 (95% CI 2.2 to 2.8) at 6, 12 and 18 months before diagnosis, respectively. Also, infections (notably of the genital and urinary tracts), IA-comorbidities and chronic diseases were more prevalent in cases than controls, but more evenly spread out over the whole 6-year period before IA. A decision tree was created including all symptoms and diseases.ConclusionThere was an increased frequency of primary care visits for musculoskeletal symptoms, infections and comorbidities prior to the diagnosis of IA. This diverging trend is present for 4–6 years, but becomes statistically significant 1.5 years before the diagnosis. Validation of these results is warranted.
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De Maio, Fernando, Alessandro Fichera, Vincenzo De Luna, Federico Mancini, and Roberto Caterini. "Orthopaedic Aspects of Marfan Syndrome: The Experience of a Referral Center for Diagnosis of Rare Diseases." Advances in Orthopedics 2016 (2016): 1–6. http://dx.doi.org/10.1155/2016/8275391.
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Marfan syndrome is caused by mutations in the fibrillin-1 gene (FBN1). The most important features affect the cardiovascular system, eyes, and skeleton. The aim of this study was to report the most frequent musculoskeletal alterations observed in 146 patients affected by Marfan syndrome. Fifty-four patients (37%) underwent cardiac surgery and 11 of them received emergent surgery for acute aortic dissection. Ectopia lentis was found in 68 patients (47%) whereas myopia above 3D occurred in 46 patients (32%). Musculoskeletal anomalies were observed in all patients with Marfan syndrome. In 88 patients (60.2%), the associated “wrist and thumb sign” was present; in 58 patients (39.7%), pectus carinatum deformity; in 44 patients (30.1%), pectus excavatum; in 49 patients (33.5%), severe flatfoot; in 31 patients (21.2%), hindfoot deformity; in 54 patients (36.9%), reduced US/LS ratio or increased arm span-height ratio; in 37 patients (25.3%), scoliosis or thoracolumbar kyphosis; in 22 patients (15%), reduced elbow extension (170° or less). Acetabular protrusion was ascertained on radiographs in 27 patients (18.4%). Orthopaedic aspects of the disease are very important for an early diagnosis; however, we have not observed definite correlations between the extent of orthopaedic involvement and aortic complications.
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Titova, E. V., and A. Yu Zakharov. "COMPARE THE DEGREE OF INFORMATION OF MODERN METHODS OF DIAGNOSTICS OF SPORT HORSES." International Journal of Veterinary Medicine, no. 3 (October 18, 2022): 279–84. http://dx.doi.org/10.52419/issn2072-2419.2022.3.279.
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In connection with the development of equestrian sports, the proportion of traumatic injuries of the musculoskeletal system of sports horses is also increasing. In the working activity of a modern veterinary specialist, visual research methods should have certain qualities, namely: they should be small in size for ease of transportation to various points in the city or region, easy to apply in practice, and also qualitatively visualize the location of the pathological focus. That is why the search for the most effective method of visual diagnosis of diseases accompanied by injuries of the musculoskeletal system is an important direction in scientific research. To conduct this study, 10 dressage horses with traumatic injuries of the superficial flexor of the thoracic limbs were examined in the conditions of equestrian complexes in the Leningrad Region. Conducted a study on the information content of various diagnostic methods, in particular thermographic, ultrasound and radiological. Comparing the degree of information content of modern methods, we can conclude that for an accurate diagnosis and a complete analysis of traumatic injuries, it is necessary to use various methods of visual diagnostics. Improvement of known methods, in particular, such as infrared thermography, will make it possible to identify injuries of the musculoskeletal system of horses at the early stages of the development of the disease, immediately before the onset of clinical signs, and to monitor changes in dynamics for the selected treatment regimen. Accordingly, timely diagnosis and prognosis of injuries remains an open topic for research in the scientific activities of veterinarians, therefore, we consider the search for new methods that meet the criteria used to identify several groups of diseases at once is relevant and significant.
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Voloshyn, O. I., O. V. Glubochenko, I. V. Pankiv, V. G. Glubochenko, and I. V. Prysiazhniuk. "Rheumatic manifestations of thyroid pathology. Literature review." Clinical Endocrinology and Endocrine Surgery, no. 1 (April 6, 2022): 57–67. http://dx.doi.org/10.30978/cees-2022-1-57.
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Thyroid disease can be accompanied by a variety of rheumatic manifestations, ranging from early growth defects during infancy to adult manifestations such as arthralgias, myalgias, myopathy, acropachy, arthritis, osteoporosis. Objective — to provide a summarizing current literature on the analysis of a variety of musculoskeletal disorders in hyperthyroidism and hypothyroidism and possible mechanisms that explain this connection. Materials and methods. The authors conducted a systematic literature search for relevant Englishlanguage publications published between June 2011 and October 2021 in MedLine, PubMed, and Google Scholar. A variety of rheumatic manifestations in hyperthyroidism and hypothyroidism include: arthropathy, myopathy, adhesive shoulder capsulitis, thyroid acropachy, tunnel (carpal) syndrome, Raynaud’s phenomenon, Hoffman’s syndrome, osteoporosis. Thyroid diseases commonly cause musculoskeletal complaints and may even present with rheumatic syndromes before the nature of the underlying endocrinopathy is apparent. On occasion, thyroid disorders can mimic some rheumatic diseases and leading to diagnostic errors. On the other hand, thyroid disorders can coexist with rheumatic diseases as well as rheumatic symptoms and findings. Musculoskeletal complaints can be related to unidentified and untreated thyroid diseases. However, it is important to keep in mind that the therapy for these diseases might lead to myopathies. As a result, internists, endocrinologists, and rheumatologists should be well-versed in recognizing how thyroid illnesses influence the musculoskeletal system and must be aware of these correlations to ensure that the associated condition is not missed, or the diagnosis is not delayed. This will aid in avoiding diagnostic mistakes and provide early suspicion of thyroid pathology and correct treatment. Keywords: rheumatic manifestations, hyperthyroidism, hypothyroidism, thyroid pathology, musculoskeletal syndrome.
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Aygun, Emre, Sibel Tugce Aygun, Taciser Uysal, Fatih Aygun, Hasan Dursun, and Ahmet Irdem. "Aetiological evaluation of chest pain in childhood and adolescence." Cardiology in the Young 30, no. 5 (May 2020): 617–23. http://dx.doi.org/10.1017/s1047951120000621.
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AbstractBackground:Chest pain, as a common cause of hospital admissions in childhood, necessitates detailed investigations due to a wide range of differential diagnoses. In this study, we aimed to determine the distribution of diseases causing chest pain in children and investigate the clinical characteristics of children with chest pain.Methods:This study included 782 patients aged between 3 and 18 years who presented to a paediatric cardiology outpatient clinic with chest pain between April 2017 and March 2018. Aetiological causes and demographic features of the patients were analysed.Results:Most prevalent causes of chest pain were musculoskeletal system (33%) and psychogenic (28.4%) causes. Chest pain due to cardiac reasons was seen in eight patients (1%). Diseases of musculoskeletal and gastrointestinal systems and psychogenic disorders were significantly more common in male and female patients, respectively (p < 0.001 for all). In winter, patients’ age and the number of patients with ≥12 years were higher than those in other seasons (p < 0.001). Most of the parents (70.8%) and patients (90.2%) thought that chest pain in their children was caused by cardiac causes.Conclusion:Most of the diagnoses for chest pain in childhood period are benign and include the musculoskeletal system and psychogenic diseases. Although chest pain due to cardiac diseases is rare, a comprehensive analysis of medical history, detailed physical examination and cardiac imaging with echocardiography is needed to reach more accurate diagnoses.
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a Gallyamova, Svetlana Anifovna, Elmira Radikovna Shaykhlislamova, Liliya Fillurovna Gareeva, and Alfiya Dinislamovna Volgareva. "Clinical and diagnostic features of occupational polyneuropathy in combination with damage to the locomotor apparatus in workers of harmful professions." Terapevt (General Physician), no. 3 (March 20, 2022): 53–64. http://dx.doi.org/10.33920/med-12-2203-07.
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An urgent task for the occupational pathology service of the country is the search for objective methods for the early diagnosis of occupational diseases of the peripheral nervous system, in combination with the pathology of the musculoskeletal system, often occurring among workers of hazardous industries. Based on the analysis of electroneuromyographic and radiological research methods in 60 workers performing work with the impact of local vibration and physical overload, the degree of impairment of the peripheral nervous system and the musculoskeletal system of the upper limbs was studied in comparison with persons whose labor activity excluded contact with these labor factors. A relationship has been established between the severity of clinical and instrumental data obtained with the duration of exposure to harmful factors. Identification of lesions of the peripheral nervous system and the locomotor apparatus will ensure timely prevention and adequate therapeutic measures.
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Lehto, Mika, Kaisu Pitkälä, Ossi Rahkonen, Merja K. Laine, Marko Raina, and Timo Kauppila. "Do electronic reminders alter recorded diagnoses in primary care office-hours practices of health centers: A register-based study in a Finnish city." SAGE Open Medicine 9 (January 2021): 205031212110361. http://dx.doi.org/10.1177/20503121211036117.
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Objectives: One purpose of electronic reminders is improvement of the quality of documentation in office-hours primary care. The aim of this study was to evaluate how implementation of electronic reminders alters the rate and/or content of diagnostic data recorded by primary care physicians in office-hours practices in primary care health centers. Methods: The present work is a register-based longitudinal follow-up study with a before-and-after design. An electronic reminder was installed in the electronic health record system of the primary health care of a Finnish city to remind physicians to include the diagnosis code of the visit in the health record. The report generator of the electronic health record system provided monthly figures for the number of various recorded diagnoses by using the International Classification of Diseases, 10th edition, and the total number of visits to primary care physicians, thus allowing the calculation of the recording rate of diagnoses on a monthly basis. The distribution of diagnoses before and after implementing ERs was also compared. Results: After the introduction of the electronic reminder, the rate of diagnosis recording by primary care physicians increased clearly from 39.7% to 87.2% (p < 0.001). The intervention enhanced the recording rate of symptomatic diagnoses (group R) and some chronic diseases such as hypertension, type 2 diabetes and other soft tissue disorders. Recording rate of diagnoses related to diseases of the respiratory system (group J), injuries, poisoning and certain other consequences of external causes (group S), and diseases of single body region of the musculoskeletal system and connective tissue (group M) decreased after the implementation of electronic reminders. Conclusion: Electronic reminders may alter the contents and extent of recorded diagnosis data in office-hours practices of the primary care health centers. They were found to have an influence on the recording rates of diagnoses related to chronic diseases. Electronic reminders may be a useful tool in primary health care when attempting to change the behavior of primary care physicians.
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Carrillo-Castrillo, Jesús Antonio, Ventura Pérez-Mira, María del Carmen Pardo-Ferreira, and Juan Carlos Rubio-Romero. "Analysis of Required Investigations of Work-Related Musculoskeletal Disorders in Spain." International Journal of Environmental Research and Public Health 16, no. 10 (May 14, 2019): 1682. http://dx.doi.org/10.3390/ijerph16101682.
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Musculoskeletal disorders (MSD) are the most common source of occupational health problems in Western countries. In Spain, musculoskeletal disorders (MSDs) can be reported either as accidents or occupational diseases. When reported as an occupational disease, a full diagnosis is performed, as the compensation system needs the approval of the social security authority and a mandatory investigation has to be performed. Although many methods are available for investigating the causes of occupational accidents, occupational diseases have not been analysed with the same depth, and there is a lack of investigation methods. This paper aims to analyse the role of 43 occupational investigations of causes of musculoskeletal diseases in the prevention cycle. This study is based on the occupational investigations performed by workplaces’ occupational health and safety specialists when musculoskeletal diseases are reported. The analysis of the data involves descriptive statistics and the Φ coefficient. Based on administrative data, 68 workplaces employing 15,260 workers were surveyed and 41 workplaces with 13,201 workers submitted valid questionnaires to be analysed. The most frequent cause of reported musculoskeletal disease, in terms of primary risk, is repetitive movement. The only proposed measure with a significant association to the exposure by repetitive movements is job rotation (alternating workers between tasks within a job or between activities as a means to vary different levels of exposure). The investigation of occupational diseases has been useful in most of the cases for proposing preventive measures. Most of the workplaces surveyed have performed investigations and adopted preventive measures, but the managers of some workplaces were not aware of any disease notification regarding their workers when surveyed. More research is needed to provide tools for this important task.
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Aleksanin, S. S., V. Yu Rybnikov, Yu V. Gudz’, K. K. Rogalyov, G. Yu Sokurenko, S. V. Dudarenko, and M. V. Savel’yeva. "Specialized Medical Care for Victims of Chernobyl Accident: Specifics of Organization, Types and Volumes, Leading Classes of Diseases." Disaster Medicine, no. 4 (December 2020): 5–12. http://dx.doi.org/10.33266/2070-1004-2020-4-5-12.
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The purpose of the study is to summarize the experience and identify the features of the organization and provision of specialized medical care (SpMP) to victims of the Chernobyl accident on the basis of the A. M. Nikiforov All-Russian centre of emergency and radiation medicine of EMERCOM of Russia. Materials and methods of research. Materials of the study were the data on types and volume of specialized medical assistance in 2014-2020 on the basis of the Centre; on the leading classes of diseases demanding specialized medical care in remote period to those affected by the Chernobyl accident. Research results and their analysis. 1. The system of organization of specialized medical care for victims of the Chernobyl accident in the framework of the Union State of Russia – Belarus includes 5 main stages: planning, coordination, information and analytical, hospital and final – analytical stages. 2. The main reasons for hospitalization of victims of the Chernobyl accident were diseases of the circulatory system, of the digestive system and of the musculoskeletal system and connective tissue. 3. When providing therapeutic SpMP, special attention was paid to the diagnosis and correction of comorbid pathology; when providing surgical SpMP, to individual selection of anesthetic aids, the use of minimally invasive endoscopic surgical interventions and prevention of postoperative complications. 4. The main reasons for medical rehabilitation were diseases of the Central nervous system and sensory organs, diseases of the cardiovascular system, musculoskeletal system and peripheral nervous system.
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Barkova, A., I. Mil'shteyn, and E. Shurmanova. "Assessment of the condition of the musculoskeletal system sports horses in the Middle Urals." Agrarian Bulletin of the, no. 14 (February 3, 2021): 10–18. http://dx.doi.org/10.32417/1997-4868-2021-14-10-18.
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Abstract. Purpose. Evaluation of the effectiveness methods of visual diagnostics of diseases of the musculoskeletal system sports horses and the spread of diseases in equestrian clubs in the Middle Urals. Methods. The analysis of the diagnostic capabilities of X-ray and ultrasound research 31 sports horses of different age categories was carried out. Some of the animals had pronounced clinical signs of pathologies. The results obtained showed that 65 different pathologies were detected in 30 out of 31 examined horses, that is, in 96.7 % of animals. Disorders of the toe axis, fractures and cracks, convergence of spinous processes, end hoof, tendinitis, arthrosis of 2nd, 3rd, 4th degrees, including 1st degree, clinically not expressed were most often recorded. In young animals under the age of 1 year, such pathologies as violation of the finger axis and cracks in the bones prevail, from 1 to 3 years of age, fractures of the coffin bone were recorded, the appearance of the end hoof and a violation of the finger axis predominated, while in these groups of animals no pathologies were recorded during ultrasound. Thus, according to the results of visual diagnostics in the age groups from 0 to 3 years, there are on average 1.6 pathologies per horse, and in the age groups from 3 years and older, there are 2.3 pathologies per horse. Based on the above, we can conclude that the complex use of visual diagnostic methods has shown high efficiency in assessing the state of the musculoskeletal system in animals of all age groups. Scientific novelty. In the conditions of equestrian clubs in the Middle Urals, the most common diseases of the musculoskeletal system in sports horses have been identified and the most effective methods for their diagnosis have been determined.
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Bennett, Jackson, James W. Suliburk, and Fanny E. Morón. "Osseous Manifestations of Primary Hyperparathyroidism: Imaging Findings." International Journal of Endocrinology 2020 (February 21, 2020): 1–10. http://dx.doi.org/10.1155/2020/3146535.
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Primary hyperparathyroidism is a systemic endocrine disease that has significant effects on bone remodeling through the action of parathyroid hormone on the musculoskeletal system. These findings are important as they can aid in distinguishing primary hyperparathyroidism from other forms of metabolic bone diseases and inform physicians regarding disease severity and complications. This pictorial essay compiles bone-imaging features with the aim of improving the diagnosis of skeletal involvement of primary hyperthyroidism.
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Astrakhantseva, Maria A., Pavel F. Kiku, Sergey V. Voronin, and Anna V. Sukhova. "Prevention and diagnosis of congenital malformations." HEALTH CARE OF THE RUSSIAN FEDERATION 65, no. 3 (July 12, 2021): 230–37. http://dx.doi.org/10.47470/0044-197x-2021-65-3-230-237.
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The problem of inherited pathology remains relevant, gaining in recent decades and medical and biological and acute socio-economic importance. Purpose. To analyse statistical data on prevention and diagnosis of congenital malformations in Primorsky Krai. Material and methods. As a material of the study, the data of medical-genetic consultation and medical-genetic assistance were used. Information Federal State Statistics Service for the Primorsky Territory on the birth rate. The data were processed using descriptive statistics. Results. According to the study, during 2015-2017, within the framework of the budget 5561 (2015), 5537 (2016), and 5418 (2018), patients visited reception for the medical and genetic consultation and received the corresponding assistance. Most congenital malformation of compulsory registration was recorded in large urban districts (34.1-5.7%), and the remaining municipalities accounted for 0.2-3%. Diseases of the circulatory system, deformations of the musculoskeletal system, diseases of the urogenital system (frequency of occurrence 36.5%, 13.8%, 11.3%, respectively) dominated the structure of congenital malformations. The most common congenital malformations of mandatory registration identified during the prenatal screening - hypospadias and Down syndrome were identified. The most common congenital malformations identified during mass neonatal screening included hypothyroidism, phenylketonuria, cystic fibrosis. Conclusion. Possible reasons for the high level of congenital malformations in some areas of Primorsky Krai are lack of public awareness of the problem, environmental conditions, distance from the regional medical and genetic centre, lack of qualified specialists and modern equipment for research in municipal hospitals. However, proper medical and genetic counselling, prenatal diagnosis and monitoring play a critical role in the prevention of congenital malformations.
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Baraliakos, X., I. Redeker, M. Zacharopoulou, S. Tsiami, and J. Braun. "AB1419 PERFORMANCE OF AN EARLY TRIAGE SYSTEM FOR IDENTIFICATION OF PATIENTS WITH INFLAMMATORY RHEUMATIC DISEASES." Annals of the Rheumatic Diseases 81, Suppl 1 (May 23, 2022): 1815.1–1815. http://dx.doi.org/10.1136/annrheumdis-2022-eular.5124.
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BackgroundThe preselection of patients with suspicion of an inflammatory rheumatic disease is not easy for general practitioners and orthopedists. In countries with a limited number of practicing rheumatologists waiting lists are often long, since a full rheumatologic examination often needs a long consultation time.ObjectivesTo test the performance of an early triage strategy for early identification of patients with inflammatory rheumatic diseases.MethodsPrior to the SARS-CoV 2 pandemic, physicians caring for patients contacting a tertiary rheumatologic cente were first contacted by a health-care professional (HPR) who offered an appointment the timing of which was based on the symptoms reported (Step 1). Patients were then seen by a rheumatologist who, within a 10-minute consultation (Step 2), shortly examined the patient to determine the urgency of a planned full work up. The main outcome of the study was the comparison between the initial assessment and the final expert diagnosis (Step 3).ResultsWithin 9 months, physicians caring for 1.180 patients contacted the hospital, 972 of whom kept their appointment (82.4%). Most patients were transferred by GPs (73.1%) and orthopedists (22.1%). The mean time between Step 1 and Step 2 was 10.4 days, while 6.2% of patients were seen within 4 days, 24.4% within 7 days and 69.3% within 12 weeks. Only 36 patients (3.7%) of patients had an already established rheumatic disease. Complaints lasting between 0-4 weeks were reported by 69 (7.1%), of > 4-12 weeks by 100 (10.3%), and of > 12 weeks by 973 (82.6%) patients. Almost 90% of patients reported a pain intensity >4/10 (NRS) for < 2 weeks. An elevated CRP was found in 207 patients (24.5%). Prior treatment with glucocorticoids was reported in 163 (16.8%) and with NSAIDs in 730 (75.1% of) patients. The confirmed diagnosis at Step 3 was rheumatoid arthritis in 127 (13.1%), spondyloarthritis including psoriatic arthritis in 72 (7.4%), systemic diseases including connective tissue diseases in 112 (11.5%), vasculitides in 41 (4.2%), and crystal arthropathy in 38 (3.9%) patients, while 38 (3.9%) had an infection, a malignancy or a differential diagnosis such as Raynaud’s phenomenon or sicca syndrome. Degenerative joint diseases (n=254; 26.1%) and non-inflammatory soft tissue syndromes such as fibromyalgia (n=369; 38%) accounted for more than half of the patients.ConclusionThis study describes the performance of a standardized triage system hereby confirming the need for an early identification and preselection of patients with rheumatic musculoskeletal symptoms, including involvement of HPRs in the initial phase of contact. Based on the results, three patients with musculoskeletal complaints had to be examined in order to identify one patient with an inflammatory rheumatic disease.Disclosure of InterestsNone declared
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Løppenthin, Katrine, Bente Appel Esbensen, Mikkel Østergaard, Rikke Ibsen, Jakob Kjellberg, and Poul Jennum. "Morbidity and mortality in patients with rheumatoid arthritis compared with an age- and sex-matched control population: A nationwide register study." Journal of Comorbidity 9 (January 1, 2019): 2235042X1985348. http://dx.doi.org/10.1177/2235042x19853484.
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Objective: The aim of this study was to examine the prevalence of morbidity and mortality in patients with seropositive rheumatoid arthritis (RA). Methods: Data were obtained from national population-based registries in the period 1998–2009. Prior to the seropositive RA diagnosis (International Classification of Disorders 10th revision M05), we identified a total of 21,558 patients and 87,384 age- and sex-matched control subjects. Odds for morbidity were calculated before and after the RA diagnosis. We estimated the overall survival based on the Kaplan–Meier method. Results: Patients with RA had statistically significantly higher odds for a number of co-morbidities prior to the onset of RA including diseases of the musculoskeletal system (odds ratio (OR) 3.10, 95% confidence interval (CI) 3.00–3.21), diseases involving the immune system (OR 1.45, 95% CI 1.29–1.64), endocrine diseases (OR 1.09, 95% CI 1.01–1.17), diseases of the circulatory system (OR 1.08, 95% CI 1.03–1.14) and diseases of the respiratory system (OR 1.30, 95% CI 1.22–1.38), compared with age- and sex-matched control subjects. After the RA diagnosis, the same trend was seen with higher odds for the same co-morbidities. We found a 5-year survival of 80% (95% CI 78–81%) for patients with RA, while for control subjects it was 88% (95% CI 88–89%). Conclusion: Compared with age- and sex-matched controls, patients with seropositive RA have higher odds for several co-morbidities prior to and, particularly, after the diagnosis of RA. Furthermore, patients with RA have a lower overall survival compared with age- and sex-matched controls.
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ŁOJSZCZYK-SZCZEPANIAK, ANNA, KLAUDIUSZ O. SZCZEPANIAK, MACIEJ GRZYBEK, and BARBARA LISIAK. "Causes of consultations and results of radiological and ultrasound methods in lizard diseases (2006-2014)." Medycyna Weterynaryjna 74, no. 1 (2018): 65–69. http://dx.doi.org/10.21521/mw.5830.
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Reptiles are becoming increasingly popular animals in amateur husbandry in Poland and worldwide. The world literature, however, does not provide data on the actual causes of radiological and ultrasound consultations in certain groups of animals, including reptiles. The aim of the study was the analysis of causes and results of diagnostic imaging examinations. The study was based on the data of 75 lizards which were patients of the university diagnostic imaging service in the years 2006-2014. The most common clinical signs in those animals were visible body deformations (33.33%), loss of body weight (30.67%) and loss of appetite (26.67%). In cases in which a preliminary diagnosis had been made, the largest proportion of animals were referred with suspected post-traumatic changes (12%), dystocia (10.67%) and ileus (9.33%). In diagnostic imaging tests, musculoskeletal (29.33%) and coelomic abnormalities (40.33%) were most commonly confirmed. Coelomic changes affected mainly the liver, reproductive system and gastrointestinal tract. For the musculoskeletal system, the most frequently identified causes were the presence of post-traumatic changes, malformations of the vertebral column, as well as metabolic bone disease. Cardiorespiratory and urinary problems were observed only sporadically. In twenty-two animals (29.33%), radiographic and ultrasound examinations failed to establish a diagnosis. The results of this study provide valuable data on the cross-section of the most common problems leading to diagnostic imaging evaluation in lizards. This research demonstrates that, despite the growing popularity of exotic animals, most of the problems diagnosed in such animals still arise from inappropriate breeding and housing conditions. In most cases, diagnostic imaging provides valuable information, making it possible to implement further steps....
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Kalaycı, Defne, Mehmet Erdem Alagüney, and Ali Naci Yıldız. "The Estimated Number of Occupational Diseases and Work-Related Diseases in Turkey." Acta Medica 50, no. 3 (September 30, 2019): 17–24. http://dx.doi.org/10.32552/2019.actamedica.358.
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Objective: The number of occupational diseases are lower than expected in Turkey. We aimed to estimate the number of occupational diseases, work-related diseases, and deaths due to occupational exposures by using international estimations of attribution of workplace in this descriptive study.
Methods: The attributable fraction values to occupation for selected diseases and deaths were compiled from the literature. Information on these diseases and deaths in Turkey was obtained from national burden of disease studies and statistics of Turkish Statistical Institute. The estimated number of occupational diseases, work-related diseases and deaths due to occupational exposures were calculated by using the number of diseases and deaths in Turkey and by the fraction of occupational exposures by using literature.
Results: Based on the data of national burden of disease studies in Turkey; 321,868 musculoskeletal disorders, 79,232 to 95,845 circulatory system diseases, 38,994 to 56,992 chronic obstructive pulmonary diseases, 14,563 to 19,858 asthma cases, 29,550 hearing losses, and 4,902 to 16,341 cancer cases are estimated to be work-related. According to the Turkish Statistical Institute data, the number of deaths due to occupational causes was estimated to be 8,143 in circulatory system diseases; 1,913 in malignant tumors; and 2,130 in respiratory system diseases. However, the lowest and the highest number of occupational diseases announced by the Social Security Institution between 2007 and 2016 is 371 and 1,208, respectively.
Conclusion: There are deficiencies in the diagnosis and reporting of occupational diseases. In order to plan and implement preventive actions, data should be reported in a large scale and reliable manner.
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Aparisi Gómez, Maria Pilar, Francisco Aparisi, Alessio Giuseppe Morganti, Stefano Fanti, and Alberto Bazzocchi. "Effects of Radiation Therapy and Chemotherapy on the Musculoskeletal System." Seminars in Musculoskeletal Radiology 26, no. 03 (June 2022): 338–53. http://dx.doi.org/10.1055/s-0041-1740995.
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AbstractThe effects of radiation and chemotherapy on the musculoskeletal (MSK) system are diverse, and interpretation may be challenging. The different lines of treatment have effects on diseased and normal marrow, and they may lead to complications that must be differentiated from recurrence or progression. This review analyzes the changes induced by radiotherapy and chemotherapy in the MSK system in the adult and pediatric population, and the expected associated imaging findings. Treatments are often combined, so the effects may blend. Awareness of the spectrum of changes, complications, and their imaging appearances is paramount for the correct diagnosis. The assessment of body composition during and after treatment allows potential interventions to implement long-term outcomes and personalize treatments. Imaging techniques such as computed tomography or magnetic resonance imaging provide information on body composition that can be incorporated into clinical pathways. We also address future perspectives in posttreatment assessment.
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Greben’Kov, Sergey V., N. Yu Mal’Kova, E. V. Milutka, and O. A. Kochetova. "Clinical and hygienic evaluation of patients with occupational polyneuropathy of upper extremities." Hygiene and sanitation 99, no. 6 (July 29, 2020): 581–85. http://dx.doi.org/10.47470/0016-9900-2020-99-6-581-585.
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Introduction. The article presents the results of a study of working conditions and the health status of patients with occupational polyneuropathy (PNP) of the upper limbs. Such a clinical and hygienic assessment of people with occupational PNP contributes to the optimal examination and treatment of patients with the preliminary diagnosis who are referred to occupational pathology centers.Material and methods. The study included 236 patients of two main occupations (painters-plasterers and miners): 113 women and 123 men. Results. The average age of patients at the time of the examination was: for painters-plasterers (women) - 55.5 ± 5.7 years, for miners (men) - 53.9 ± 6.3 years. Work experience of patients with physical overload at the time of diagnosis of occupational PNP accounted for plasterers - 25.1 ± 8.0 years, for miners - 20.4 ± 6.7 years. Working conditions of plasterers and miners were revealed to contribute to the development of occupational diseases of the peripheral nervous system and musculoskeletal system from the effects of physical overload and functional overstrain of the muscles of the upper extremities. Most often occupational PNP of the upper limbs is accompanied by the parallel development of professional chronic shoulder-scapular periarthrosis, epicondylosis, myofibrosis of the forearms, and shoulder girdle (a complex of occupational pathology of the «working hand»); radiculopathy of the cervical and lumbosacral levels.Conclusions. The main common harmful factor in the examined patients is the severity of the labor process. In less than one-fourth of the examined patients (15,7%) occupational PNP of the upper limbs was the only occupational disease. In other cases, its development was accompanied by the appearance of other occupational diseases of the peripheral nervous system and the musculoskeletal system. Patients referred to the examination in occupational pathology centers with a diagnosis of “PNP of the upper extremities” need a comprehensive examination to verify a possible complex of occupational pathology.
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Cerovic, Olivera, Besir Ljuskovic, and Vladan Kovacevic. "Periodontal disease in relation to some systemic diseases." Serbian Dental Journal 50, no. 4 (2003): 197–201. http://dx.doi.org/10.2298/sgs0304197c.
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Periodontal disease is closely related to the general state of the body because it significantly influences periodontal health, as periodontal health can have an influence on the state of the body. It is known that some systemic diseases can represent a risk factor for periodontal disease such as diabetes, blood disorders and immunodefficient disorders. Reducing defensive efficiency of the body, these diseases enable the onset and the development of periodontal disease. On the other hand, concerning the role of microorganisms in the onset and the development of periodontal disease there is justified suspicion that periodontal infection might endanger general state of the body and cause some systemic diseases, such as cardiovascular, respiratory, eye, renal, skin disease and the diseases of the musculoskeletal system. The awareness of connection between periodontal disease and some systemic diseases is of great significance for the diagnosis and the therapy of periodntal disease and the disorders it may cause.
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Baraliakos, X., I. Redeker, M. Zacharopoulou, S. Tsiami, K. Tsiaousi, D. Morzeck, and J. Braun. "AB1144 DAILY CLINICAL CARE OF PATIENTS WITH MUSCULOSKELETAL COMPLAINTS – HOW HELPFUL IS A TRIAGE SYSTEM FOR EARLY RECOGNITION OF INFLAMMATORY RHEUMATIC DISEASES?" Annals of the Rheumatic Diseases 79, Suppl 1 (June 2020): 1862.2–1862. http://dx.doi.org/10.1136/annrheumdis-2020-eular.6529.
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Background:Early diagnosis and treatment are important for the management of inflammatory rheumatic diseases (RMD). However, the availability of rheumatologists is limited in most European countries and selection strategies lack sensitivity and/or specificity.Objectives:To evaluate a triage strategy that offers the possibility to see patients within 4 weeks for short term appointments in order to check the probability of an inflammatory RMD and the necessity to further evaluate the patients in due time.Methods:Physician’s and patient’s information who called our tertiary rheumatology department´s outpatient clinic for a date in the triage system were included in this analysis. The time to first appointment as assessed by a nurse (Step 1), the short evaluation by a rheumatologist in the triage (Step 2) and the patient´s complaints and the diagnoses after an extensive diagnostic evaluation (Step 3) were documented.Results:In a period of 9 months in 2018, a total of 982 patients presented. A total of 62 patients (6.3%) were considered urgent (appointment within 3 days), while 240 (24.4%) were appointed within 4 weeks at Step 2. Of the former 46 (19.2%), and of the latter 151 patients (62.9%) were diagnosed with inflammatory RMD at Step 3.In total, 334 patients (34.0%) were diagnosed with inflammatory RMD at Step 3, including 126 with RA (37.7%), 71 with axSpA/PsA (21.3%), 95 with connective tissue disease/vasculitis (28.4%) and 20 with gout (6.0%). The diagnosis suspected in Step 2 was confirmed in Step 3 in 77.9% of cases. In 217 patients, the diagnosis suspected in Step 2 was not confirmed in Step 3. Of them, 34 (15.7%) had unclear findings at Step 2 but an inflammatory RMD was found at Step 3, while 148 (68.2%) had a suspected inflammatory RMD at Step 2 but this was not confirmed at Step 3.The most frequent musculoskeletal complaint at the time point of referral was pain in small peripheral joints (hands and/or feet) in 858 patients (87.4%), in large peripheral joints (knees, shoulders and/or hips) in 780 patients (79.4%) and back pain in 682 patients (69.5%). Fever, night sweats and unclear weight loss was reported by 50 patients (5.1%), while 210 patients (24.5%) presented with findings suspicious of inflammatory RMD such as elevated CRP of unclear origin, and 43 patients (4.8%) because of a threat of organ damage such as unclear elevation of creatinine, as reported by the referring physician. In addition, 167 patients (17.0%) had received glucocorticoids prior to referral, 87 (52.1%) of which finally did not receive the diagnosis of inflammatory RMD at Step 3, while 737 patients (75.1%) were receiving NSAIDs prior to referral.Conclusion:In this prospective evaluation of a triage system where all patients were pre-screened by a nurse and were seen within 4 weeks by a rheumatologist, clinical differentiation could be performed timely due to a successfully structured triage system. The initially suspected diagnosis was finally confirmed in ≥75% of cases, while ≥1/3 of patients had a definite inflammatory RMD.This work was supported by an unrestricted Grant from AbbvieDisclosure of Interests:Xenofon Baraliakos Grant/research support from: Grant/research support from: AbbVie, BMS, Celgene, Chugai, Merck, Novartis, Pfizer, UCB and Werfen, Consultant of: AbbVie, BMS, Celgene, Chugai, Merck, Novartis, Pfizer, UCB and Werfen, Speakers bureau: AbbVie, BMS, Celgene, Chugai, Merck, Novartis, Pfizer, UCB and Werfen, Imke Redeker: None declared, Maria Zacharopoulou: None declared, Styliani Tsiami: None declared, Konstantia Tsiaousi: None declared, Doris Morzeck: None declared, Juergen Braun Grant/research support from: Abbvie (Abbott), Amgen, BMS, Boehringer, Celgene, Celltrion, Centocor, Chugai, Eli Lilly and Company, Medac, MSD (Schering Plough), Mundipharma, Novartis, Pfizer (Wyeth), Roche, Sanofi- Aventis, and UCB Pharma, Consultant of: Abbvie (Abbott), Amgen, BMS, Boehringer, Celgene, Celltrion, Centocor, Chugai, EBEWE Pharma, Eli Lilly and Company, Medac, MSD (Schering-Plough), Mundipharma, Novartis, Pfizer (Wyeth), Roche, Sanofi-Aventis, and UCB Pharma, Speakers bureau: Abbvie (Abbott), Amgen, BMS, Boehringer, Celgene, Celltrion, Centocor, Chugai, EBEWE Pharma, Eli Lilly and Company, Medac, MSD (Schering-Plough), Mundipharma, Novartis, Pfizer (Wyeth), Roche, Sanofi-Aventis, and UCB Pharma
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Kolenkiewicz, Małgorzata, Andrzej Włodarczyk, and Joanna Wojtkiewicz. "Diagnosis and Incidence of Spondylosis and Cervical Disc Disorders in the University Clinical Hospital in Olsztyn, in Years 2011–2015." BioMed Research International 2018 (2018): 1–7. http://dx.doi.org/10.1155/2018/5643839.
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Background. Disorders connected with the musculoskeletal and central nervous system dysfunction are the most significant clinical problem worldwide. Our earlier research has shown that back and spinal disorders and lumbar disc disorders were most frequently diagnosed using MRI scanner at the University Clinical Hospital (UCH) in Olsztyn in years 2011–2015. We have also observed that another two diseases of spinal column, spondylosis and cervical disc disorders, were also very prevalent. The main objective of this work was to analyze the prevalence of spondylosis and cervical disc disorders in the study population diagnosed at UCH in years 2011–2015. Methods. The digital database including patients’ diagnostic and demographic information was generated based on MRI reports from years 2011–2015 and analyzed using SPSS software. Results. Within the study group (n=13298) the most frequently MRI-diagnosed diseases were musculoskeletal group (M00–M99; n=7711; 57,98%) and cervical disc disorders (M50; n=1659; 12,47%) and spondylosis (M47, n=611; 4,59%). More women (67%) than men (33%) were enrolled in the study, and the largest fraction of the study population was in the range of 51–60 years, with about 1/3 of cases of both diseases diagnosed in early age range of 31–40 years. Conclusion. Significant number of patients presenting with either of the spine disorders at the young age of 31–40 years points to the necessity of introducing methods preventing disorders of the vertebral column at younger age, preferably at school age.
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Örgüç, Sebnem, and Remide Arkun. "Tumor-like Lesions of Bone and Soft Tissues and Imaging Tips for Differential Diagnosis." Seminars in Musculoskeletal Radiology 24, no. 06 (December 2020): 613–26. http://dx.doi.org/10.1055/s-0040-1721378.
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AbstractIn the musculoskeletal system, tumor-like lesions may present similar imaging findings as bone and soft tissue tumors and can be defined as tumors on radiologic examinations. Misinterpretation of the imaging findings can lead to inappropriate clinical management of the patient.There is still some debate regarding the pathophysiology and origin of tumor-like lesions that include congenital, developmental, inflammatory, infectious, metabolic, reactive, posttraumatic, post-therapeutic changes, and some miscellaneous entities causing structural changes. Although tumor-like lesions are historically defined as non-neoplastic lesions, some of them are classified as real neoplasms.We discuss a spectrum of entities mimicking tumors of bone and soft tissues that include various non-neoplastic diseases and anatomical variants based on imaging findings.
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Gromakina, E. V., N. V. Tyunina, E. D. Egorova, and E. A. Sozurakova. "Pathogenetic aspects of cataract in comorbid conditions." Modern technologies in ophtalmology, no. 5 (September 30, 2022): 65–68. http://dx.doi.org/10.25276/2312-4911-2022-5-65-68.
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Relevance. Research by ophthalmologists, biologists, biochemists, biophysicists, physiologists have shown the significance of xeno- and endobiotic effects on the induction of cataracts and other degenerative diseases of the structures and membranes of the eye. Objective research goal was an evaluation of comorbid background in people of different ages with a diagnosis of senile cataract. Material and methods an analysis of the case histories of 173 patients of an independent sample with a diagnosis of "senile cataract" admitted for planned inpatient surgical treatment was carried out. The evaluation was carried out by decades of human life: younger than 40 years old, 41–50 years old, 51–60 years old, 61–70 years old, 71–80 years old and over 80 years old. The Charlson method was used to calculate the comorbidity index. Results patients who had senile cataract and concomitant somatic diseases, the most frequent- diseases of the cardiovascular system – 129 (74.6 %); violation of carbohydrate metabolism – 35 (20.2 %); diseases of the central nervous system – 33 (19.1 %); musculoskeletal system – 30 (17.3 %); diseases of the respiratory system – 19 (11.0 %). Conclusions. 1. A human's age of 51–60 years should be considered critical for the occurrence of senile cataract. 2. In the decade of life 51–60 years, there is an increase in persons with senile cataract by 3.3 and the frequency of concomitant somatic pathology (according to the index of comorbidity) by 2.25. Keywords: senile cataract, age, somatic diseases, index of comorbidity
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Hofmann, Sigrun R., Angela Roesen-Wolff, Gabriele Hahn, and Christian M. Hedrich. "Update: Cytokine Dysregulation in Chronic Nonbacterial Osteomyelitis (CNO)." International Journal of Rheumatology 2012 (2012): 1–7. http://dx.doi.org/10.1155/2012/310206.
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Chronic nonbacterial osteomyelitis (CNO) with its most severe form chronic recurrent multifocal osteomyelitis (CRMO) is a non-bacterial osteitis of yet unknown origin. Secondary to the absence of both high-titer autoantibodies and autoreactive T lymphocytes, and the association with other autoimmune diseases, it was recently reclassified as an autoinflammatory disorder of the musculoskeletal system. Since its etiology is largely unknown, the diagnosis is based on clinical criteria, and treatment is empiric and not always successful. In this paper, we summarize recent advances in the understanding of possible etiopathogenetic mechanisms in CNO.
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Kokolakis, Georgios, Kerstin Wolk, Sylke Schneider-Burrus, Stefanie Kalus, Sebastian Barbus, Susana Gomis-Kleindienst, and Robert Sabat. "Delayed Diagnosis of Hidradenitis Suppurativa and Its Effect on Patients and Healthcare System." Dermatology 236, no. 5 (2020): 421–30. http://dx.doi.org/10.1159/000508787.
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Background: Hidradenitis suppurativa (HS) is a neglected chronic inflammatory disease with long delay in diagnosis. Besides pain, purulent discharge, and destruction of skin architecture, HS patients experience metabolic, musculoskeletal, and psychological disorders. Objectives: To determine the delay in HS diagnosis and its consequences for patients and the healthcare system. Methods: This was a prospective, multicenter, epidemiologic, non-interventional cross-sectional trial carried out in Germany and based on self-reported questionnaires and medical examinations performed by dermatologists. In total, data of 394 adult HS patients were evaluated. Results: The average duration from manifestation of first symptoms until HS diagnosis was 10.0 ± 9.6 (mean ± SD) years. During this time, HS patients consulted on average more than 3 different physicians – most frequently general practitioners, dermatologists, surgeons, gynecologists – and faced more than 3 misdiagnoses. Diagnosis delay was longer in younger and non-smoking patients. In most cases, HS was correctly diagnosed by dermatologists. The longer the delay of diagnosis, the greater the disease severity at diagnosis. Delayed HS diagnosis was also associated with an increased number of surgically treated sites, concomitant diseases, and days of work missed. Conclusion: This study demonstrates an enormous delay in the diagnosis of HS, which results in more severe disease. It also shows for the first time that a delay in diagnosis of a chronic inflammatory disease leads to a higher number of concomitant systemic disorders. In addition to the impaired health status, delayed diagnosis of HS was associated with impairment of the professional life of affected people.
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Traudt, A. K., V. D. Zavadovskaya, T. V. Zhogina, and Ye I. Fedorova. "MAGNETIC RESONANCE IMAGING IN THE DIAGNOSIS OF JUVENILE IDIOPATHIC ARTHRITIS." Bulletin of Siberian Medicine 14, no. 1 (February 28, 2015): 110–19. http://dx.doi.org/10.20538/1682-0363-2015-1-110-119.
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Juvenile idiopathic arthritis (JIA) are a group of socially significant diseases of childhood because of the high prevalence of a chronic nature, as well as a large percentage of early disability. JIA is a collection of diseases that have different start, course and outcome, as well as various etiologies, which emphasizes the difficulties in the diagnosis process in children. When this disease is progressive in nature, leads to loss of function of the musculoskeletal system, severe disability at an early age and, therefore, needs early diagnosis and adequate therapy appointment.Significant role in identifying pathology osteoarticular system belongs radiological methods and routine radiography remains the most widely used technique included in the classification criteria of the majority of rheumatic diseases. However, it is well known that secondary structural changes in the bones precedes roentgen period, and therefore the X-rays can not be regarded as a method of early diagnosis with articular syndrome. Widely introduced in recent years, magnetic resonance imaging (MRI) has more say in the assessment of capabilities of the joints, as in addition to assessment of bone allows quantitatively and qualitatively assess changes in the synovial membrane, articular cartilage, the presence and severity of inflammatory changes in the periarticular soft tissue and bone tissue. The data obtained using MRI may be used for diagnosis, prognosis, and monitoring response to treatment, including early stage disease.Nevertheless, despite the obvious opportunities MRI, this technique is not widely used, including the lack of clear diagnostic criteria for the disease, the lack of centralized research validated, standardized protocols for conducting MRI studies of children with articular syndrome. Thus, research is warranted to address a number of clinical and diagnostic aspects in JIA, in particular the development of the scoring system assessing the severity and progression of the disease.