Academic literature on the topic 'Musculo skeletal disease'

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Journal articles on the topic "Musculo skeletal disease"

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Perry, J. David. "Electrodiagnosis in musculo-skeletal disease." Best Practice & Research Clinical Rheumatology 19, no. 3 (June 2005): 453–66. http://dx.doi.org/10.1016/j.berh.2005.01.007.

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Wright, Stephen. "Musculo-skeletal and neurological aspects of Lyme disease." International Musculoskeletal Medicine 38, no. 3-4 (October 2016): 91–94. http://dx.doi.org/10.1080/17536146.2016.1226462.

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Landau, Kurt, Regina Brauchler, Marianela Diaz-Meyer, Johannes Kiesel, Andreas Lenz, Herwig Meschke, and Angelika Presl. "Occupational stress factors and musculo-skeletal disease in patients at a rehabilitation center." Occupational Ergonomics 10, no. 4 (September 26, 2012): 139–53. http://dx.doi.org/10.3233/oer-2012-0198.

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Disorders of the musculo-skeletal system are one of the main occupational diseases occurring in industrial countries and the number of reported cases is rapidly increasing, especially among the older age groups. Musculo-skeletal diseases can be influenced by a number of stress factors arising during physical work. The aim of this study is to identify the physical work stress factors, to which persons already suffering from musculo-skeletal diseases (patients at a rehabilitation center) have been exposed in their work, and, firstly, to examine whether these data can be used to predict the probability of future musculo-skeletal disorders in workers occupying this type of job, secondly, to determine how these factors interact with each other in the development of these disorders. Trained specialists in occupational medicine using a program called Medical Job-oriented Rehabilitation (MJOR), collected data on 6668 patients by means of a standardized checklist called Bavaria Rehabilitation Assessment Method (BRA). Analysis of the recursive binary partitioning trees revealed that 19 predictor variables corresponding to age and gender, plus repetitive operations, rotation in sedentary position, degree of hand force used and forced head/neck postures were good predictors for the disorders of the hand-/arm system, the cervico-brachial syndrome and the impingement syndrome of shoulder.
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Lewith, George. "Acupuncture Points and Trigger Points: Their Use in Musculo-skeletal Disease." Journal of Orthopaedic Medicine 15, no. 1 (January 1993): 8–9. http://dx.doi.org/10.1080/1355297x.1993.11719707.

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Balogun, Rufai A., Dike C. Obalum, Suleiman O. Giwa, Thomas O. Adekoya-Cole, Chidiebere N. Ogo, and George O. Enweluzo. "Spectrum of musculo-skeletal disorders in sickle cell disease in Lagos, Nigeria." Journal of Orthopaedic Surgery and Research 5, no. 1 (2010): 2. http://dx.doi.org/10.1186/1749-799x-5-2.

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Barbieri, Enza, Giovanni Frezza, Ombretta Martelli, Stefano Neri, Mario Mercuri, Franco Gherlinzoni, Gaetano Bacci, Antonia Mancini, Carlo Putti, and Lucio Babini. "Non Conventional Fractionation in Radiotherapy of the Musculo-Skeletal Sarcomas." Tumori Journal 84, no. 2 (March 1998): 167–70. http://dx.doi.org/10.1177/030089169808400213.

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In 1989 we started an accelerated hyperfractionated schedule of radiotherapy (two 1.6 Gy daily fractions) in standard risk localized Ewing's sarcoma of bone, with the aim at reducing late effects in young patients and at improving disease control through a better integration of treatment modalities. From 1991, the same schedule was used in preoperative radiotherapy of adult soft tissue sarcomas of the extremities: the main purpose was to reduce the time to surgery and to evaluate surgical complications in comparison with a previous experience of hypofractionated radiotherapy (one 3 Gy daily fraction). From 1991 to 1997, 76 patients with Ewing's sarcoma and 24 patients with soft tissue sarcoma were treated at our Institution. Results and complication rates are analyzed in comparison with historical data. In Ewing's sarcoma, a correct evaluation of improvement in local control was difficult because of changing treatment policy (bulky disease was not included in the present series). Late effects, as evaluated in patients with a minimum follow-up of 3 years, occurred with similar incidence, but at higher total dose levels in patients treated with accelerated hyperfractionation. In patients with soft tissue sarcomas, incidence of surgical complications is reduced as compared to historical experience. Major problems of wound healing were seen in association with intraoperative brachitherapy boost.
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Burdea, G. C. "Virtual Rehabilitation – Benefits and Challenges." Methods of Information in Medicine 42, no. 05 (2003): 519–23. http://dx.doi.org/10.1055/s-0038-1634378.

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Summary Objectives: To discuss the advantages and disadvantages of rehabilitation applications of virtual reality. Methods: VR can be used as an enhancement to conventional therapy for patients with conditions ranging from musculo-skeletal problems, to stroke-induced paralysis, to cognitive deficits. This approach is called “VR-augmented rehabilitation.” Alternately, VR can replace conventional interventions altogether, in which case the rehabilitation is “VR-based.” If the intervention is done at a distance, then it is called “telerehabilitation.” Simulation exercises for post-stroke patients have been developed using a “teacher object” approach or a video game approach. Simulations for musculo-skeletal patients use virtual replicas of rehabilitation devices (such as rubber ball, power putty, peg board). Phobia-inducing virtual environments are prescribed for patients with cognitive deficits. Results: VR-augmented rehabilitation has been shown effective for stroke patients in the chronic phase of the disease. VR-based rehabilitation has been improving patients with fear of flying, Vietnam syndrome, fear of heights, and chronic stroke patients. Telerehabilitation interventions using VR have improved musculo-skeletal and post-stroke patients, however less data is available at this time. Conclusions: Virtual reality presents significant advantages when applied to rehabilitation of patients with varied conditions. These advantages include patient motivation, adaptability and variability based on patient baseline, transparent data storage, online remote data access, economy of scale, reduced medical costs. Challenges in VR use for rehabilitation relate to lack of computer skills on the part of therapists, lack of support infrastructure, expensive equipment (initially), inadequate communication infrastructure (for telerehabilitation in rural areas), and patient safety concerns.
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Kagramanova, Anna V., Oleg V. Knyazev, Oleg V. Knyazev, Oleg V. Knyazev, Dmitrii S. Kulakov, Dmitrii S. Kulakov, Dmitrii S. Kulakov, et al. "Interdisciplinary approach is a key of efficient treatment in patients with immunoinflammatory diseases. Case report." Consilium Medicum 23, no. 5 (2021): 440–43. http://dx.doi.org/10.26442/20751753.2021.5.200821.

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The article is devoted to clinical case of concomitant immune-inflammatory diseases: Crohn disease, ankylosing spondylitis, primary sclerosing cholangitis. Chronic immunoinflammatory diseases (CID) caused disability, characterized by similar genetic and immunological factors. The emergence of genetically engineered biological drugs has changed the prognosis for both musculo-skeletal diseases and inflammatory bowel disease (IBD). The intersection of the therapeutic spectrum in CID is a very important point in choosing the tactics of management of patients with these pathologies. This clinical case demonstrates the importance of early diagnosis of immunoinflammatory diseases and application of genetically engineered biological drugs, that contributes to prevention disability and enhancement of quality of life of IBD patients. It is concluded that treatment of immunoinflammatory diseases should be carried out taking into account the course of the IBD and the multidisciplinary approach, which requires close cooperation of doctors of various specialties.
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Rahman, M. A., M. A. Islam, M. A. Rahman, A. K. Talukder, M. S. Parvin, and M. T. Islam. "CLINICAL DISEASES OF RUMINANTS RECORDED AT THE PATUAKHALI SCIENCE AND TECHNOLOGY UNIVERSITY VETERINARY CLINIC." Bangladesh Journal of Veterinary Medicine 10, no. 1-2 (July 9, 2013): 63–73. http://dx.doi.org/10.3329/bjvm.v10i1-2.15648.

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This study was conducted at the Patuakhali Science and Technology University Veterinary Clinic, Babugonj, Barisal during the period from January 2008 to December 2011 to report the four years clinical diseases of ruminants. A total of 1241 clinical cases (793 cattle and 448 goats) were recorded and analyzed. Diagnosis of each of the clinical cases was made on clinical history, clinical signs, and faecal examination for parasitic cases. The clinical cases were primarily categorized into three major groups, namely, (1) Medicinal, (2) Gynaeco-obstetrical and (3) Surgical cases. Medicinal cases constituted highest percentage (cattle 84.1% and goats 81.0%) in comparison to gynaeco-obstetrical (cattle 4.7% and goats 1.1%) and surgical (cattle 11.2% and goats 17.9%) cases. Among the medicinal cases in cattle, highest percentage of cases was recorded with parasitic diseases (50.4%), followed by general systemic states (14.8%) and digestive disorders (14.2%). Other cases were respiratory disorders (5.5%), infectious diseases (4.6%), skin conditions (3.4%), eye disease (3.1%), urogenital disorders (1.5%), metabolic diseases (1.3%) and musculo-skeletal disorders (0.9%). In case of goats, the highest cases was recorded with digestive disorders (22.9%), followed by parasitic diseases (20.4%) and respiratory disorders (16.8%). Other Medicinal cases in goats were eye diseases (13.5%), infectious diseases (11.8%), general systemic states (9.6%), musculo-skeletal disorder (3.3%), skin diseases (0.8%) and nutritional deficiency diseases (0.8%). Among the gynaeco-obstetrical cases, anestrus (59.5%) in cattle and metritis (40.0%) in goats were recognized as the major gynaeco-obstetric problems. Traumatic wounds (cattle - 52.8%, goat - 28.8%) and castration (31.3%) in goats were recognized as the main disorders which required surgical interventions. It may be concluded that a number of diseases with various percentages have been occurring in the Babugonj upazila and this report will help to prioritize any control measures against major disease conditions reported in this study. However, it is required to estimate the prevalence of diseases in the population of that upazila to have more comprehensive information on the diseases of cattle and goat.DOI: http://dx.doi.org/10.3329/bjvm.v10i1-2.15648
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Dorozhkin, Sergey V. "Calcium Orthophosphate Bioceramics." Journal of Biomimetics, Biomaterials and Tissue Engineering 5 (February 2010): 57–100. http://dx.doi.org/10.4028/www.scientific.net/jbbte.5.57.

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Ceramics used for the repair and reconstruction of diseased or damaged parts of the musculo-skeletal system, termed bioceramics, can be bioinert, bioresorbable and bioactive, as well as porous for tissue ingrowth. This review is devoted to calcium orthophosphates, which belong to the categories of bioresorbable and bioactive bioceramics. There have been a number of major advances made in this field during the past 30 – 40 years. From initial work on development of bioceramics that were tolerated in the physiological environment, emphasis has now shifted towards the use of bioceramics that interact with bone tissue by forming a direct bond. By structural and compositional control, it is now possible to choose whether the bioceramics of calcium orthophosphates are biologically stable once incorporated within the skeletal structure or whether they are resorbed over time. Current biomedical applications of calcium orthophosphate bioceramics include replacements for hips, knees, teeth, tendons and ligaments, as well as repair for periodontal disease, maxillofacial reconstruction, augmentation and stabilization of the jawbone, spinal fusion and bone fillers after tumor surgery.
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Dissertations / Theses on the topic "Musculo skeletal disease"

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PISPERO, ALBERTO. "THE USE OF THE OPERATING MICROSCOPE IN DENTAL PRACTISE: POSTURAL ANALYSIS AND CLINICAL EVALUATION." Doctoral thesis, Università degli Studi di Milano, 2019. http://hdl.handle.net/2434/695210.

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THE USE OF OPERATING MICROSCOPE IN DENTAL PRACTISE: POSTURAL ANALYSIS AND CLINICAL EVALUATION Abstract Author: Alberto Pispero Dipartimento di Scienze Biomediche, Chirurgiche ed Odontoiatriche, Università degli Studi di Milano The study is in collaboration with Politecnico di Milano, Dipartimento di Ingegneria Elettronica, prof. Marco Marcon Study design: randomized controlled clinical trial. Setting of the clinical trial: Dental Clinic G. Vogel, via Beldiletto ASST Santi Carlo e Paolo Ospedale. Dr. Alberto Pispero, the surgeon for all the interventions; Prof. Giovanni Lodi is the head of research. PURPOSE The study investigates the effectiveness of microscope in dental practice in terms of posture improvement for the operator and clinical advantages for the patients. We carried out 4 studies: 1. Postural assessment in dentistry based on multiple markers tracking 2. The use of magnifying instrument for the extraction of lower third molar: Postural assessment 3. The use of magnifying instrument for the extraction of lower third molar: Clinical assessment 4. The influence of dental loupes on the quality of adhesive removal in orthodontic debonding: in vitro study. Background Attention and awareness towards MSDs in the dental profession has increased considerably in last years. From recent literature reviews, it is learned that prevalence of MSDs in dentists is 64-93%. Use of magnification systems improves the operator's visual capabilities, improves posture, and helps to prevent the onset of back and neck disorders. Moreover, the goal of dental treatment is to preserve tissues with minimally invasive prosthetics, conservatives and endodontics therapies, and to reconstruct periodontal soft and hard tissues performing microsurgery treatments in order to get the best aesthetic results and the least pain and complications. Over time, the degree of precision required immediately calls for magnification. METHODS Study 1: First, we conducted a study (study 1) on posture assessment to find an innovative method of postural analysis. In order to do that we worked with Politecnico of Milano. We presented a novel approach for upper limb posture assessment based on the tracking of a set of planar markers placed on the clothes of the worker. Thanks to this non-invasive approach, we were able to follow the 3D position and orientation of all the limbs involved in a specific activity during the job execution. Data will be evaluated through the index RULA (rapid upper limb assesment) to define whether there is a change in exposure to the risk of MSDs (Muskolo - skeletal - disease). Study 2: We used the method mentioned above in a randomized controlled three arms clinical trial where the surgeons performed 90 intervention. It was evaluated dentist posture during extraction of third lower molars depending on whether the operator performs the intervention by the use of surgical loupes or surgical microscope systems or performs a naked eyes surgery. Static and dynamic operator’s posture has been monitored by markers positioned on a slim fit t-shirt and high definition cameras acquired data in real time (study 2). Study 3: To evaluate whether the use magnifying system, could influence the postoperative course of a patient after extraction of a lower third molar. Each patient will be recalled for follow-up visits at 7 days. During this session will be carried out the removal of stitches and data will be recorded as follows: VAS pain and trismus, number of painkillers taken, control photographs, Posse Scale. These data were analyzed considering type of magnification and difficulty of extraction (study 3). Study 4: In order to investigate the effect of using different magnifying systems for removal of composite residues and in the prevention of iatrogenic enamel damage we conducted an in vitro study. 27 permanent extracted teeth were used, The teeth were randomized into 3 groups named. Each tooth was photographed and scanned with the intraoral scanner CS3600-Carestream before bracket placement (T0), post bracket positioning (T1), after removal of bracket (T2) and after debonding (T3). RESULTS Study 1: The analysis that we performed can be easily integrated into classical ergonomics assessment tools like RULA providing an objective methodology that does not involve an operator in a subjective interpretation of the monitored job. Study 2: From step 1 to step 8 in RULA worksheet, we put the same score in all cases, in the same way in steps 11, 13 and 14. By the use of magnification system, the operator’s posture didn’t change in terms of leg positioning or arm raising and wrist twist. We verified that despite the big range between neck bending, from 40 to 3 degrees, the final RULA score is the same for all interventions. Study 3: From the results obtained it is clear that the methods taken into consideration, the operating microscope, the surgical loupes with coaxial illumination and the naked eye, do not have a statistically significant influence on pain intensity (VAS), quality of life (PoSSe) or the number of painkillers taken by patients. The complexity of the magnifying system does not increase the duration of the operating time Study 4: There is a statistically significant difference between the procedures performed with the naked eye and those performed with surgical loupes. This result can be explained by greater attention and accuracy in removing the residual composite from the operator when using magnification systems. Microscope and surgical loupes were slower but got the best results in removal of composite remnants. Intraoral scanner that we used to evaluate the teeth surfaces does not appear useful to discriminate damage to the enamel. CONCLUSION We developed a new approach for posture assessment, precise and accurate, and we have had 3d data of the whole body, which can discriminate differences of one degree. We need long term studies conducted on many dentists (male and female) and a new method of posture data analysis to define the correlation between upper limbs posture and WMSDs accurately. We wanted to test magnification systems in fields of dentistry different from endodontics in which microscope is generally used. Even if data had no statistical significance, on the other hand microscope didn't affect the operating time. Despite common perceptions, the use of the microscope in oral surgery didn't slow down the intervention. We decided to test the microscope potential in debonding. In our research, the procedures performed without a magnification system are on average faster than those performed with the aid of a magnification. This result can be explained by greater attention and accuracy in removing the residual composite from the operator when using magnification systems. Microscope and surgical loupes were slower but got the best results in removal of composite remnants.
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Foxton, Ruth. "Dysferlin in skeletal muscle and skeletal muscle disease." Thesis, University of Newcastle Upon Tyne, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.268429.

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Terry, Rebecca Louise. "Modification of skeletal muscle phenotype to treat Duchenne muscular dystrophy." Thesis, Royal Veterinary College (University of London), 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618307.

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Hopkinson, Nicholas Shaun. "Skeletal muscle dysfunction in chronic obstructive pulmonary disease." Thesis, Imperial College London, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.417140.

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Swallow, Elisabeth. "Skeletal muscle dysfunction in chronic obstructive pulmonary disease." Thesis, Imperial College London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.508993.

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Torres-Palsa, Maria Jose. "ICAM-1 in Skeletal Muscle Disease and Regeneration." University of Toledo / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1461860958.

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Behnke, Bradley Jon. "Skeletal muscle oxygen exchange in health and disease /." Search for this dissertation online, 2003. http://wwwlib.umi.com/cr/ksu/main.

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Vlahovich, Nicole. "The role of cytoskeletal tropomyosins in skeletal muscle and muscle disease." Thesis, View thesis, 2007. http://handle.uws.edu.au:8081/1959.7/32176.

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Cells contain an elaborate cytoskeleton which plays a major role in a variety of cellular functions including: maintenance of cell shape and dimension, providing mechanical strength, cell motility, cytokinesis during mitosis and meiosis and intracellular transport. The cell cytoskeleton is made up of three types of protein filaments: the microtubules, the intermediate filaments and the actin cytoskeleton. These components interact with each other to allow the cell to function correctly. When functioning incorrectly, disruptions to many cellular pathway have been observed with mutations in various cytoskeletal proteins causing an assortment of human disease phenotypes. Characterization of these filament systems in different cell types is essential to the understanding of basic cellular processes and disease causation. The studies in this thesis are concerned with examining specific cytoskeletal tropomyosin-defined actin filament systems in skeletal muscle. The diversity of the actin filament system relies, in part, on the family of actin binding proteins, the tropomyosins (Tms). There are in excess of forty Tm isoforms found in mammals which are derived from four genes: α, β, γ and δTm. The role of the musclespecific Tms in striated muscle is well understood, with sarcomeric Tm isoforms functioning as part of the thin filament where it regulates actin-myosin interactions and hence muscle contraction. However, relatively little known about the roles of the many cytoskeletal Tm isoforms. Cytoskeletal Tms have been shown to compartmentalise to form functionally distinct filaments in a range of cell types including neurons (Bryce et al., 2003), fibroblasts (Percival et al., 2000) and epithelial cells (Dalby-Payne et al., 2003). Recently it has been shown that cytoskeletal Tm, Tm5NM1 defines a cytoskeletal structure in skeletal muscle called the Z-line associated cytoskeleton (Z-LAC) (Kee et al., 2004).The disruption of this structure by over-expression of an exogenous Tm in transgenic mice results in a muscular dystrophy phenotype, indicating that the Z-LAC plays an important role in maintenance of muscle structure (Kee et al., 2004). In this study, specific cytoskeletal Tms are further investigated in the context of skeletal muscle. Here, we examine the expression, localisation and potential function of cytoskeletal Tm isoforms, focussing on Tm4 (derived from the δ- gene) and Tm5NM1 (derived from the γ-gene). By western blotting and immuno-staining mouse skeletal muscle, we show that cytoskeletal Tms are expressed in a range of muscles and define separate populations of filaments. These filaments are found in association with a number of muscle structures including the myotendinous junction, neuromuscular junction, the sarcolemma, the t-tubules and the sarcoplasmic reticulum. Of particular interest, Tm4 and Tm5NM1 define cytoskeletal elements in association with the saroplasmic reticulum and T-tubules, respectively, with a separation of less than 90 nm between distinct filamentous populations. The segregation of Tm isoforms indicates a role for Tms in the specification of actin filament function at these cellular regions. Examination of muscle during development, regeneration and disease revealed that Tm4 defines a novel cytoskeletal filament system that is orientated perpendicular to the sarcomeric apparatus. Tm4 is up-regulated in both muscular dystrophy and nemaline myopathy and also during induced regeneration and focal repair in mouse muscle. Transition of the Tm4-defined filaments from a predominsnatly longitudinal to a predominantly Z-LAC orientation is observed during the course of muscle regeneration. This study shows that Tm4 is a marker of regeneration and repair, in response to disease, injury and stress in skeletal muscle. Analysis of Tm5NM1 over-expressing (Tm5/52) and null (9d89) mice revealed that compensation between Tm genes does not occur in skeletal muscle. We found that the levels of cytoskeletal Tms derived from the δ-gene are not altered to compensate for the loss or gain of Tm5NM1 and that the localisation of Tm4 is unchanged in skeletal muscle of these mice. Also, excess Tm5NM1 is sorted correctly, localising to the ZLAC. This data correlates with evidence from previous investigations which indicates that Tm isoforms are not redundant and are functionally distinct (Gunning et al., 2005). Transgenic and null mice have also allowed the further elucidation of cytoskeletal Tm function in skeletal muscle. Analyses of these mice suggest a role for Tm5NM1 in glucose regulation in both skeletal muscle and adipose tissue. Tm5NM1 is found to colocalise with members of the glucose transport p fibres and analysis of both transgenic and null mice has shown an alteration to glucose uptake in adipose tissue. Taken together these data indicate that Tm5NM1 may play a role in the translocation of the glucose transport molecule GLUT4. In addition to this Tm5NM1 may play a role in adipose tissue regulation, since over-expressing mice found to have increased white adipose tissue and an up-regulation of a transcriptional regulator of fat-cell formation, PPAR-γ.
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Vlahovich, Nicole. "The role of cytoskeletal tropomyosins in skeletal muscle and muscle disease." View thesis, 2007. http://handle.uws.edu.au:8081/1959.7/32176.

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Thesis (Ph.D.)--University of Western Sydney, 2007.
A thesis presented to the University of Western Sydney, College of Health and Science, School of Natural Sciences, in fulfilment of the requirements for the degree of Doctor of Philosophy. Includes bibliographies.
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Petrany, Michael J. "Consequences of Cell Fusion and Multinucleation for Skeletal Muscle Development and Disease." University of Cincinnati / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1595847866440328.

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Books on the topic "Musculo skeletal disease"

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Walton, John N. Skeletal muscle pathology. 2nd ed. Edinburgh: Churchill Livingstone, 1992.

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Robert, Wortmann, ed. Diseases of the skeletal muscle. Philadelphia: Lippincott Williams & Wilkins, 2000.

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R, Preedy Victor, and Peters Timothy J, eds. Skeletal muscle: Pathology, diagnosis, and management of disease. London: Greenwich Medical Media, 2002.

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G, Laing Nigel, ed. The sarcomere and skeletal muscle disease. New York, N.Y: Springer Science+Business Media, 2008.

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Laing, Nigel G., ed. The Sarcomere and Skeletal Muscle Disease. New York, NY: Springer New York, 2008. http://dx.doi.org/10.1007/978-0-387-84847-1.

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L, Mastaglia Frank, and Walton John Nicholas, eds. Skeletal muscle pathology. 2nd ed. Edinburgh: Churchill Livingstone, 1992.

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Atlas of skeletal muscle pathology. Lancaster: MTP Press, 1985.

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Pelechas, Eleftherios, Evripidis Kaltsonoudis, Paraskevi V. Voulgari, and Alexandros A. Drosos. Illustrated Handbook of Rheumatic and Musculo-Skeletal Diseases. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-03664-5.

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Watson, Ian. Aspects of homoeopathy: Musculo-skeletal problems. Kendal, Cumbria, England: Cutting Edge Publications, 1998.

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Bottinelli, Roberto, and Carlo Reggiani, eds. Skeletal Muscle Plasticity in Health and Disease. Dordrecht: Springer Netherlands, 2006. http://dx.doi.org/10.1007/1-4020-5177-8.

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Book chapters on the topic "Musculo skeletal disease"

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Streifler, M. B. "Sensory and musculo-skeletal dysfunction in Parkinson’s disease—premonitory and permanent." In Key Topics in Brain Research, 33–39. Vienna: Springer Vienna, 1989. http://dx.doi.org/10.1007/978-3-7091-8994-8_4.

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Herrero-Hernandez, Pablo, Atze J. Bergsma, and W. W. M. Pim Pijnappel. "Generation of Human iPSC-Derived Myotubes to Investigate RNA-Based Therapies In Vitro." In Methods in Molecular Biology, 235–43. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2010-6_15.

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AbstractAlternative pre-mRNAsplicing can be cell-type specific and results in the generation of different protein isoforms from a single gene. Deregulation of canonical pre-mRNAsplicing by disease-associated variants can result in genetic disorders. Antisense oligonucleotides (AONs) offer an attractive solution to modulate endogenous gene expression through alteration of pre-mRNAsplicing events. Relevant in vitro models are crucial for appropriate evaluation of splicing modifying drugs. In this chapter, we describe how to investigate the splicing modulating activity of AONs in an in vitro skeletal muscle model, applied to Pompe disease. We also provide a detailed description of methods to visualize and analyze gene expression in differentiated skeletal muscle cells for the analysis of muscledifferentiation and splicing outcome. The methodology described here is relevant to develop treatment options using AONs for other genetic muscle diseases as well, including Duchenne muscular dystrophy, myotonic dystrophy, and facioscapulohumeral muscular dystrophy.
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Evans, William J. "Skeletal Muscle Effects on the Skeleton." In Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 978–85. Ames, USA: John Wiley & Sons, Inc., 2013. http://dx.doi.org/10.1002/9781118453926.ch117.

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Caron, Marc-André, Marie-Eve Thériault, Richard Debigaré, and François Maltais. "Skeletal Muscle Dysfunction." In Chronic Obstructive Pulmonary Disease, 137–59. Totowa, NJ: Humana Press, 2011. http://dx.doi.org/10.1007/978-1-60761-673-3_9.

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Meyer, Michael Andrew. "Diseases of Skeletal Muscle." In Neurologic Disease, 177–86. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-39581-4_9.

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Lynch, Gordon S., David G. Harrison, Hanjoong Jo, Charles Searles, Philippe Connes, Christopher E. Kline, C. Castagna, et al. "Skeletal Muscle." In Encyclopedia of Exercise Medicine in Health and Disease, 789. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-540-29807-6_3038.

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Anderson, Janice R. "Motor Neuron Disease." In Atlas of Skeletal Muscle Pathology, 37–43. Dordrecht: Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-009-4866-2_4.

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Lynch, Gordon S., David G. Harrison, Hanjoong Jo, Charles Searles, Philippe Connes, Christopher E. Kline, C. Castagna, et al. "Skeletal Muscle Disorder." In Encyclopedia of Exercise Medicine in Health and Disease, 789. Berlin, Heidelberg: Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-540-29807-6_4520.

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Romero, N. B., M. Coquet, and H. Carrier. "Histopathology of Skeletal Muscle Mitochondria." In Mitochondrial Diseases, 343–55. Berlin, Heidelberg: Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/978-3-642-59884-5_26.

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Manabe, Yasuko. "Mechanism of Skeletal Muscle Contraction: Intracellular Signaling in Skeletal Muscle Contraction." In Musculoskeletal Disease Associated with Diabetes Mellitus, 139–53. Tokyo: Springer Japan, 2016. http://dx.doi.org/10.1007/978-4-431-55720-3_10.

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Conference papers on the topic "Musculo skeletal disease"

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Shimizu, K., N. Yamamura, and S. Takagi. "NUMERICAL STUDY OF CENTRAL NERVOUS SYSTEM, MUSCULO-SKELETAL SYSTEM, AND THEIR COUPLING TOWARD MOTOR DYSFUNCTION IN PARKINSON’S DISEASE." In 10th World Congress on Computational Mechanics. São Paulo: Editora Edgard Blücher, 2014. http://dx.doi.org/10.5151/meceng-wccm2012-19008.

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Wagner, Hallie, Dawn Lowe, and Victor Barocas. "Reduced Compliance in Patellar Tendons From a Mouse Model of Muscular Dystrophy." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80762.

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Muscular dystrophies are degenerative diseases that affect primarily skeletal muscles. Most studies of muscular dystrophy focus on muscles, but tendons are an important part of the musculotendon complex that transmits forces from muscles to bones. As the disease progresses, tendon shortening occurs, and some patients require tendon release or cord lengthening surgery to increase tendon length [1]. Despite the prevalence of these surgeries, very little is known about the mechanical properties of tendons in muscular dystrophy patients, or how they change as the tendon remodels or compensate in response to muscle degeneration.
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Cassino, Theresa R., Masaho Okada, Lauren M. Drowley, Joseph Feduska, Johnny Huard, and Philip R. LeDuc. "Using Mechanical Environment to Enhance Stem Cell Transplantation in Muscle Regeneration." In ASME 2007 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2007. http://dx.doi.org/10.1115/sbc2007-176545.

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Muscle-derived stem cell (MDSC) transplantation has shown potential as a therapy for cardiac and skeletal muscle dysfunction in diseases such as Duchenne muscular dystrophy (DMD). In this study we explore mechanical environment and its effects on MDSCs engraftment into cardiac and skeletal muscle in mdx mice and neoangiogenesis within the engraftment area. We first looked at transplantation of the same number of MDSCs into the heart and gastrocnemius (GN) muscle of dystrophic mice and the resulting dystrophin expression. We then explored neoangiogenesis within the engraftments through quantification of CD31 positive microvessels. This study is important to aid in determining the in vivo environmental factors leading to large graft size which may aid in determining optimum transplantation conditions for muscle repair.
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Cassino, Theresa R., Masaho Okada, Lauren Drowley, Johnny Huard, and Philip R. LeDuc. "Mechanical Stimulation Improves Muscle-Derived Stem Cell Transplantation for Cardiac Repair." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192941.

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Muscle-derived stem cells (MDSCs) have been successfully transplanted into both skeletal (1) and cardiac muscle (2) of dystrophin-deficient (mdx) mice, and show potential for improving cardiac and skeletal dysfunction in diseases like Duchenne muscular dystrophy (DMD). Our previous study explored the regeneration of dystrophin-expressing myocytes following MDSC transplantation into environments with distinct blood flow and chemical/mechanical stimulation attributes. After MDSC transplantation within left ventricular myocardium and gastrocnemius (GN) muscles of the same mdx mice, significantly more dystrophin-positive fibers were found within the myocardium than in the GN. We hypothesized that the differences in mechanical loading of the two environments influenced the transplantation and explored whether using MDSCs exposed to mechanical stimulation prior to transplantation could improve transplantation. Our study shows increased engraftment into the heart and GN muscle for cells pretreated with mechanical stretch for 24 hours. This increase was significant for transplantation into the heart. These studies have implications in a variety of applications including mechanotransduction, stem cell biology, and Duchenne muscular dystrophy.
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Neal, Devin, Mahmut Selman Sakar, and H. Harry Asada. "Bioengineered Fascicle-Like Skeletal Muscle Tissue Constructs." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80228.

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Tissue engineered skeletal muscle constructs have and will continue to be valuable in treating, and testing various muscle injuries and diseases. However a significant drawback to numerous methods of producing 3D skeletal muscle constructs grown in vitro is that muscle cell density as a fraction of total volume or mass, is often significantly lower than muscle found in vivo. Therefore a method to increase muscle cell density within a construct is needed.
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Jauhari, Arif, Kuat Prabowo, and Arfia Fridianti. "ANALYSIS OF RELATED FACTORS WITH SUBJECTIVE COMPLICATIONS MUSCULO SKELETAL DISEASES." In Proceedings of the 1st International Conference on Inter-professional Health Collaboration (ICIHC 2018). Paris, France: Atlantis Press, 2019. http://dx.doi.org/10.2991/icihc-18.2019.85.

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Abdelmoez, Alshaimaa AB, Michael Orth, and Andreas Neueder. "A25 Fiber type analysis in huntington disease skeletal muscle." In EHDN 2022 Plenary Meeting, Bologna, Italy, Abstracts. BMJ Publishing Group Ltd, 2022. http://dx.doi.org/10.1136/jnnp-2022-ehdn.25.

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Fadil, Rabie, Asenath X. A. Huether, Robert Brunnemer, Andrew P. Blaber, Jau-Shin Lou, and Kouhyar Tavakolian. "Skeletal Muscle Pump Impairment in Parkinson's Disease: Preliminary Results." In 2021 Computing in Cardiology (CinC). IEEE, 2021. http://dx.doi.org/10.23919/cinc53138.2021.9662690.

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Koppes, Ryan A., Nathan R. Schiele, and David T. Corr. "An Electromechanical Bioreactor for Scaffold-Free Skeletal Muscle Tissue Engineering." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53415.

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The loss of functional muscle from genetic disease, traumatic injury, or surgical excisions results in a physiologic deficiency that continues to remain without an effective clinical treatment [1]. Engineering functional muscle tissue in vitro for replacement in vivo may offer a potential remedy for this clinical demand. However, in vitro muscle constructs in two- and three-dimensions have yet to fully exhibit the dynamic mechanical responses of physiological muscle [2]. Furthermore, the application of mechanical and electrical stimulation in vitro has shown promise for growing contractile tissue [3], but these have been limited to 2-D and/or rely on inhibitory scaffold techniques. For these reasons, we sought a new approach to utilize both extrinsic growth and maturation cues, in addition to the myoblasts’ innate propensity to differentiate and produce functional myotubes in vitro, for the development of clinically-relevant skeletal muscle replacements.
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Poberezhets, Vitalii, Yuriy Mostovoy, and Hanna Demchuk. "Skeletal muscle dysfunction in patients with chronic obstructive pulmonary disease and coronary artery disease." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa662.

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