Relevant bibliographies by topics / Muschio

Academic literature on the topic 'Muschio'

Author: Grafiati
Published: 11 March 2023

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Journal articles on the topic "Muschio"

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Duente, Tim, Justin Schulte, Max Pfeiffer, and Michael Rohs. "MuscleIO." Proceedings of the ACM on Interactive, Mobile, Wearable and Ubiquitous Technologies 2, no. 2 (July 5, 2018): 1–21. http://dx.doi.org/10.1145/3214267.

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Kaiser, Herbert. ",,Satanische Blendung“ Ernst Barlachs apokalyptischer Humor in seinem nachgelassenen Roman Der gestohlene Mond." Literatur für Leser 37, no. 3 (January 1, 2014): 141–60. http://dx.doi.org/10.3726/90068_141.

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Nachdem Adolf Muschg Barlachs Roman zu seinem ,,Jahrhundertbuch“ erklärt und damit die Familientradition seiner Würdigung erneuert hatte1, die Walter Muschg2 und sein Schüler Heinz Schweizer schon um 1950 begründeten3, blieb die Rezeptionsgeschichte dieser letzten literarischen Arbeit Barlachs insgesamt doch mehr als verhalten. Das hat Gründe: Es gibt eine fast überbordende Literatur zu ihm als darstellendem Künstler; immerhin noch eine – mit der Zeit arg schrumpfende – Auseinandersetzung mit seinen Dramen. Seine Prosaschriften bleiben aber im Schatten dieser Wahrnehmung, nicht nur weil das Bild von Barlach, dem Plastiker und Zeichner, so dominiert, sondern auch, weil er als Erzähler den Leser mit Gedanken, Vorstellungen und Bildern, mit sprachlichen Eigenwilligkeiten konfrontiert, für die es in der zeitverwandten Literatur der 30er und 50er Jahre kaum Anknüpfungsmöglichkeiten gibt. Speziell für diesen Roman kommt dessen katastrophisches Überlebens- und Editionsschicksal hinzu. Er konnte, nach kriegsbedingter Verschüttung und Beschädigung, erst 10 Jahre nach Barlachs Tod veröffentlicht werden4. Aber bald nach dem Krieg bestimmte die Gruppe 47 das öffentliche literarische Bewusstsein. Die verdienstvollen Publikationen seiner Dramen, Briefe und Prosaschriften5, auch des Gestohlenen Monds, konnten nur den Dramen eine begrenzte Aufmerksamkeit verschaffen.
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Kita, Shunbun, Hitoshi Nishizawa, Yosuke Okuno, Masaki Tanaka, Atsutaka Yasui, Morihiro Matsuda, Yukio Yamada, and Iichiro Shimomura. "Competitive binding of musclin to natriuretic peptide receptor 3 with atrial natriuretic peptide." Journal of Endocrinology 201, no. 2 (February 20, 2009): 287–95. http://dx.doi.org/10.1677/joe-08-0551.

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Musclin is a novel skeletal muscle-derived secretory factor that was isolated by our group. Musclin contains a region homologous to natriuretic peptides (NPs). This study investigated the interaction between musclin and NP receptors (NPRs). Musclin specifically bound to NPR3, but not to NPR1 or NPR2. Musclin and atrial natriuretic peptide (ANP) competed for binding to NPR3. We conducted binding assays using various synthetic musclin peptides and mutant musclin proteins. The first NP-homologous region in musclin (88LDRL91) and the second homologous region (117MDRI120) were responsible cooperatively for high-affinity binding to NPR3. The first NP-homologous region was more importantly associated with binding to NPR3, than the second homologous region. The competitive nature of musclin with ANP for the natriuretic clearance receptor NPR3 was also confirmed in vivo. We conclude that musclin binds to NPR3 competitively with ANP and may affect ANP concentrations in a local or systemic manner.
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Lin, Jia-Wei, Cheng-Chia Tsai, Li-Jen Chen, Ho-Shan Niu, Chen Kuei Chang, and Chiang-Shan Niu. "Characterization of Musclin as a New Target for Treatment of Hypertension." BioMed Research International 2014 (2014): 1–7. http://dx.doi.org/10.1155/2014/354348.

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Musclin is a novel skeletal muscle-derived factor found in the signal sequence trap of mouse skeletal muscle cDNAs. Recently, it has been demonstrated that musclin is involved in the pathogenesis of spontaneously hypertensive rats (SHRs). However, it is known as a genetic hypertension model. In the present study, we aim to investigate the role of musclin in another animal model of hypertension and characterize the direct effect of musclin on vascular contraction. The results show that expression of musclin was increased in arterial tissues isolated from DOCA-salt induced hypertensive rats or the normal rats received repeated vasoconstriction with phenylephrine. Additionally, direct incubation with phenylephrine did not modify the expression of musclin in thein vitrostudies. Also, the direct effect of musclin on the increase of intracellular calcium was observed in a concentration-dependent manner. These results provide the evidence to support that musclin is involved in hypertension. Thus, musclin is suitable to be considered as a novel target for treatment of hypertension.
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Nishizawa, Hitoshi, Morihiro Matsuda, Yukio Yamada, Kenichiro Kawai, Emi Suzuki, Makoto Makishima, Toshio Kitamura, and Iichiro Shimomura. "Musclin, a Novel Skeletal Muscle-derived Secretory Factor." Journal of Biological Chemistry 279, no. 19 (March 24, 2004): 19391–95. http://dx.doi.org/10.1074/jbc.c400066200.

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Skeletal muscle is involved in the homeostasis of glucose and lipid metabolism. We hypothesized that the skeletal muscle produces and secretes bioactive factor(s), similar to adipocytokines secreted by fat tissue. Here, we report the identification of a novel secretory factor, musclin, by signal sequence trap of mouse skeletal muscle cDNAs. Musclin cDNA encoded 130 amino acids, including NH2-terminal 30-amino acid signal sequence. Musclin protein contained a region homologous to natriuretic peptide family, and KKKR, a putative serine protease cleavage site, similar to the natriuretic peptide family. Full-length musclin protein and KKKR-dependent cleaved form were secreted in media of musclin cDNA-transfected mammalian cell cultures. Musclin mRNA was expressed almost exclusively in the skeletal muscle of mice. Musclin mRNA levels in skeletal muscle were markedly low in fasted, increased upon re-feeding, and were low in streptozotocin-treated insulin-deficient mice. Musclin mRNA expression was induced at late stage in the differentiation of C2C12 myocytes. In myocytes, insulin increased, while epinephrine, isoproterenol, and forskolin reduced musclin mRNA, all of which are known to increase the cellular content of cyclic AMP, a counter-regulator to insulin. Pathologically, overexpression of musclin mRNA was noted in the muscles of obese insulin-resistant KKAy mice. Functionally, recombinant musclin significantly attenuated insulin-stimulated glucose uptake and glycogen synthesis in myocytes. In conclusion, we identified musclin, a novel skeletal muscle-derived secretory factor. Musclin expression level is tightly regulated by nutritional changes and its physiological role could be linked to glucose metabolism.
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Clark, Audra, Ryan M. Huebinger, Deborah L. Carlson, Steven E. Wolf, and Juquan Song. "Serum Level of Musclin Is Elevated Following Severe Burn." Journal of Burn Care & Research 40, no. 5 (June 11, 2019): 535–40. http://dx.doi.org/10.1093/jbcr/irz101.

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Abstract Muscle wasting induced by severe burn worsens clinical outcomes is associated with hyperglycemia. A novel muscle-specific secretory factor, musclin, was reported to regulate glucose metabolism with a homologous sequence of natriuretic peptides. The purpose of the study was to investigate musclin expression in response to burn injury in both human and animal models. Serum was collected from 13 adult burn patients and circulating levels of musclin protein were measured via elisa. The cytokine profile was measured by Bio-Plex multiple immunoassay. Following the clinical study, we used a burn rat model with 40% TBSA to study the time course of musclin expression till day 14. Rat serum and muscle tissue sample were harvested. Finally, an in vitro study was applied to investigate whether the muscle cell C2C12 myoblast expressed musclin under 10% burn serum stimulation. Pearson analysis showed that there was a significant positive correlation of musclin expression to total body surface area of burn in patients (P &= .038). Musclin expression was significantly positively correlated with IL-4, IL-7, IL-12, and IL-13 in burn patients’ serum (P < .05). In the animal study, we found that the musclin level evaluated at 6 hours and 1 day in burn rat serum (P < .05). In vitro, musclin mRNA expression significantly increased with burn serum stimulation at 24 hours (P < .05). In conclusion, serum level of musclin elevated both in human patients and burn animals; musclin was correlated with the severity of burn injury as well as with an elevated cytokine profile in patients; burn serum-stimulated musclin expression in vitro further identified the resource of musclin expression after burn.
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Chen, Wen-Jia, Yue Liu, Yu-Bin Sui, Bo Zhang, Xiao-Hui Zhang, and Xin-Hua Yin. "Increased circulating levels of musclin in newly diagnosed type 2 diabetic patients." Diabetes and Vascular Disease Research 14, no. 2 (February 10, 2017): 116–21. http://dx.doi.org/10.1177/1479164116675493.

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Background: Musclin is a newly identified skeletal muscle–derived secretory factor, which has been recently characterized as a stimulator that induces insulin resistance in mice. However, the pathophysiological role of musclin in humans remains poorly understood. The aim of this study was to explore the potential correlations between musclin plasma levels and various metabolic parameters in patients with type 2 diabetes mellitus. Materials and methods: In this hospital-based study, plasma samples were collected from the enrolled individuals, including 38 newly diagnosed, treatment-naive type 2 diabetes mellitus patients and 41 age- and gender-matched control subjects. Plasma musclin levels were examined by radioimmunoassay. Results: Compared with the control group, musclin plasma levels were significantly higher in untreated type 2 diabetes mellitus patients. Musclin levels in the plasma of newly diagnosed type 2 diabetes mellitus patients were positively correlated with fasting plasma glucose, haemoglobin A1c, serum insulin, triglycerides and homeostasis model assessment of insulin resistance. Furthermore, multivariate logistic regression analysis showed that the level of musclin was associated with the presence of type 2 diabetes mellitus. Receiver operating characteristic curve analysis yielded an area under the curve for musclin of 0.718 in type 2 diabetes mellitus. Conclusion: The circulating concentration of musclin was significantly increased in type 2 diabetes mellitus patients. Our results suggest that musclin has a strong relationship with insulin resistance in type 2 diabetes mellitus.
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Guo, Qian, Hailong Hu, Xiaohuan Liu, DaQian Yang, Yao Yin, Boya Zhang, Hongjuan He, et al. "C/EBPβ mediates palmitate-induced musclin expression via the regulation of PERK/ATF4 pathways in myotubes." American Journal of Physiology-Endocrinology and Metabolism 316, no. 6 (June 1, 2019): E1081—E1092. http://dx.doi.org/10.1152/ajpendo.00478.2018.

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Musclin is a muscle-secreted cytokine that disrupts glucose uptake and glycogen synthesis in type 2 diabetes. The purpose of this study was to investigate the mechanisms responsible for the regulation of musclin gene expression in response to treatment with palmitate. RNA sequencing results showed that biological processes activated by palmitate are mainly enriched in endoplasmic reticulum (ER) stress. The protein kinase RNA-like ER kinase (PERK) signaling pathway is involved in the regulation of musclin expression induced by palmitate. Chromatin immunoprecipitation data showed that activating transcription factor 4 (ATF4)—downstream of PERK—bound to the promoter of the C/EBPβ gene. Notably, C/EBPβ also contains a binding site in the region −94~−52 of the musclin gene promoter. Knockdown or knockout of PERK and ATF4 using short hairpin RNA or CRISPR-Cas9 decreased the expression of C/EBPβ and musclin induced by palmitate. Furthermore, knockdown and knockout of C/EBPβ alleviated the high expression of musclin in response to treatment with palmitate. Moreover, CRISPR-Cas9 knockout of the region −94~−52 in which C/EBPβ binds to the promoter of musclin abrogated the induction of high musclin expression caused by palmitate. Collectively, these findings suggest that treatment with palmitate activates the PERK/ATF4 signaling pathway, which in turn increases the expression of C/EBPβ. C/EBPβ binds directly to the promoter of the musclin gene and upregulates its expression.
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Subbotina, Ekaterina, Ana Sierra, Zhiyong Zhu, Zhan Gao, Siva Rama Krishna Koganti, Santiago Reyes, Elizabeth Stepniak, et al. "Musclin is an activity-stimulated myokine that enhances physical endurance." Proceedings of the National Academy of Sciences 112, no. 52 (December 14, 2015): 16042–47. http://dx.doi.org/10.1073/pnas.1514250112.

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Exercise remains the most effective way to promote physical and metabolic wellbeing, but molecular mechanisms underlying exercise tolerance and its plasticity are only partially understood. In this study we identify musclin—a peptide with high homology to natriuretic peptides (NP)—as an exercise-responsive myokine that acts to enhance exercise capacity in mice. We use human primary myoblast culture and in vivo murine models to establish that the activity-related production of musclin is driven by Ca2+-dependent activation of Akt1 and the release of musclin-encoding gene (Ostn) transcription from forkhead box O1 transcription factor inhibition. Disruption of Ostn and elimination of musclin secretion in mice results in reduced exercise tolerance that can be rescued by treatment with recombinant musclin. Reduced exercise capacity in mice with disrupted musclin signaling is associated with a trend toward lower levels of plasma atrial NP (ANP) and significantly smaller levels of cyclic guanosine monophosphate (cGMP) and peroxisome proliferator-activated receptor gamma coactivator 1-α in skeletal muscles after exposure to exercise. Furthermore, in agreement with the established musclin ability to interact with NP clearance receptors, but not with NP guanyl cyclase-coupled signaling receptors, we demonstrate that musclin enhances cGMP production in cultured myoblasts only when applied together with ANP. Elimination of the activity-related musclin-dependent boost of ANP/cGMP signaling results in significantly lower maximum aerobic capacity, mitochondrial protein content, respiratory complex protein expression, and succinate dehydrogenase activity in skeletal muscles. Together, these data indicate that musclin enhances physical endurance by promoting mitochondrial biogenesis.
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Tsechkovski, Mark S. "Musculo-skeletal diseases." Acta Orthopaedica Scandinavica 69, sup281 (January 1998): 61–62. http://dx.doi.org/10.1080/17453674.1998.11744796.

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Dissertations / Theses on the topic "Muschio"

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Falomo, Jari. "Sviluppo di metodiche innovative nel campo del biomonitoraggio ambientale." Doctoral thesis, Università degli studi di Trieste, 2009. http://hdl.handle.net/10077/3167.

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2007/2008
Il lavoro svolto per il conseguimento del Dottorato di Ricerca mira allo sviluppo di metodiche originali per la determinazione di microinquinanti organici nell’ambiente che possano essere applicate in piani di monitoraggio ambientale su larga scala. Sono state impiegate metodiche analitiche innovative e processi di accumulo e bioaccumulo per mappare la distribuzione ambientale di contaminanti chimici pericolosi ed identificare aree esposte a stress ambientali su cui focalizzare interventi di gestione. Le attività sono state svolte in stretta collaborazione con il Dipartimento Provinciale di Trieste dell’Agenzia Regionale per la Protezione dell’Ambiente del Friuli Venezia Giulia (ARPA FVG). Tale circostanza ha orientato il lavoro verso lo sviluppo di metodologie caratterizzate da economia operativa, sia in termini di tempi d’esecuzione, che di costi e semplicità d’uso. Questo perché i metodi di riferimento richiedono spesso procedure lunghe e/o costose, difficili da affrontare da parte di organi di controllo su cui gravano carichi operativi routinari elevati. In dettaglio il lavoro è stato articolato in due filoni principali distinti. Il primo studio riguarda lo sviluppo di un metodo di analisi di composti organostannici in ambiente marino. Tali sostanze (in particolare il tributilstagno) sono state impiegate per decenni come additivi antivegetativi nelle pitture navali e ad esse è stato attribuito un effetto come modulatori endocrini (endocrine disruptors) su organismi marini. Tra gli effetti più noti di queste sostanze c’è il fenomeno dell’imposex nei gasteropodi marini, ossia l’imposizione di caratteri maschili su individui femmine. Gli attuali metodi di riferimento sono difficoltosi soprattutto in termini di preparazione dei campioni, impedendo così la pianificazione di monitoraggi su larga scala per valutare la presenza ed il bioaccumulo di queste sostanze nell’ecosistema marino. Tali informazioni sono fondamentali per lo sviluppo di modelli interpretativi che mettano in relazione la presenza di questi stressori ambientali con alterazioni fisiologiche negli organismi che ne vengono a contatto. Sono state messe a punto ed ottimizzate delle metodiche automatizzabili ed accurate per la determinazione del tributilstagno e dei suoi prodotti di degradazione in acque, sedimenti e biota, sfruttando la microestrazione in fase solida (SPME) accoppiata alla gascromatografia con rivelazione di massa. Le metodiche sono state validate attraverso l’analisi di materiali di riferimento certificati e la partecipazione, con risultati molto positivi, a circuiti di calibrazione interlaboratorio di livello internazionale. Il metodo applicato alle matrici biologiche è stato testato su ecosistemi della regione Friuli Venezia Giulia, confermando di essere veloce e sensibile e fornendo il territorio di un presidio di controllo efficace anche per questi contaminanti, i cui effetti sull’uomo non sono ancora stati approfonditi. Il secondo studio è stato basato sull’identificazione di metodi di screening tramite campionatori passivi per valutare la presenza di Idrocarburi Policiclici Aromatici aerodispersi nell’ambiente terrestre. Tali inquinanti hanno un’elevata rilevanza ambientale in quanto sono composti praticamente ubiquitari, alcuni dei quali, tra cui il benzo[a]pirene, sono ritenuti carcinogenici o mutagenici. I campionatori passivi, dal costo contenuto e di facile preparazione, consentono di ottenere informazioni sulla presenza di IPA a seguito dell’esposizione per qualche settimana in aria ambiente, presentando il vantaggio di non necessitare né di pompe di aspirazione né di allacciamento alla corrente elettrica. Come bioaccumulatore è stato utilizzato l’Hypnum cupressiforme, specie di muschio già ampiamente utilizzata come accumulatore di metalli grazie alla sua ampia diffusione sul territorio italiano e che si è dimostrato efficiente anche nei confronti degli IPA. Parallelamente è stato sviluppato in maniera innovativa l’impiego di una matrice sintetica costituita da fibre di polietilentereftalato (dacron). La capacità di accumulo delle due matrici è stata testata in alcune sessioni di campionamento, nelle quali campioni di muschi e di dacron sono stati esposti contemporaneamente in due siti della città di Trieste. È stata determinata la ripetibilità dei campionatori passivi ed i dati sono stati confrontati con le concentrazioni di PTS (particolato totale sospeso) ottenute dai campionatori attivi dell’ARPA FVG. Entrambe le matrici si sono rivelate adatte per il monitoraggio di IPA aerodispersi. I Quadrelli (nome dato ai campionatori costituiti da dacron) sono in grado di accumulare una quantità maggiore di IPA in rapporto al loro peso mentre il muschio presenta una migliore capacità di accumulo in rapporto alla superficie esposta. Il muschio, inoltre, ha evidenziato una migliore ripetibilità dei dati ed una migliore correlazione con i dati di IPA ottenuti dall’analisi del particolato totale sospeso. Muschio e Quadrelli sono stati utilizzati per impostare una prima mappatura della provincia di Trieste e della sua zona industriale, fornendo risultati confrontabili ed evidenziando come le maggiori criticità siano legate alle sorgenti antropiche presenti nella parte meridionale della provincia. Dall’esperienza maturata nel corso del lavoro è emersa la necessità di utilizzare, nelle campagne di monitoraggio, griglie di campionamento particolarmente fitte per ottenere il maggior numero di dati utili per l’elaborazione di mappe di distribuzione dettagliate. Questo è possibile grazie al basso costo dei campionatori testati e al fatto che non necessitano né di allacciamenti elettrici né di manutenzione durante la fase di esposizione. Le griglie di monitoraggio basate su campionatori passivi sono un ottimo strumento per integrare le reti di monitoraggio istituzionale, basate su sistemi normati di campionamento attivo (come ad esempio il PM10), estendendo a costi contenuti la base di dati su cui imperniare misure di gestione ambientale.
XXI Ciclo
1976
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Muschiol, Jan [Verfasser]. "Engineering of enzymatic redox cascades involving oxygenases / Jan Muschiol." Greifswald : Universitätsbibliothek Greifswald, 2016. http://d-nb.info/1108596681/34.

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Muschiol, Roman [Verfasser]. "Begegnungsqualität in Bürogebäuden : Ergebnisse einer empirischen Studie / Roman Muschiol." Aachen : Shaker, 2007. http://d-nb.info/1163610054/34.

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Costa, Dirceu. "Estudo eletromiografico do musculo esternocleidomastoideo." [s.n.], 1985. http://repositorio.unicamp.br/jspui/handle/REPOSIP/288233.

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Orientador: Mathias Vitti
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba
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Resumo: Com o auxílio de um eletromiógrafo marca Teca TE4, de duplo canal, e utilizando-se eletrodos de superfície tipo Beckman, o músculo esternocleidomastóideo, de ambos os lados, foi estudado em 30 indivíduos jovens e sadios, na faixa etária de 19 a 28 anos, sendo 15 do sexo masculino e 15 do sexo feminino. Dentre esses indivíduos, 6 apresentavam padrão respiratório do tipo diafragmático, 10 do tipo misto e 14 do tipo costal. Foram encontradas atividades eletromiográficas durante os movimentos de: extensão livre da cabeça; flexão e protração da cabeça, livres e contra-resistência; rotação heterolateral da cabeça; inclinação homolateral da cabeça; inspiração profunda livre; inspiração profunda só pela boca; inspiração profunda só pelo nariz; e inspiração profunda brusca. Os movimentos foram executados nas posições: sentado, em decúbito dorsal, e pedalando uma bicicleta ergométrica, com carga de 1 a 2 kgs e velocidade de 25 a 30 Km/h., durante aproximadamente 15 minutos
Abstract: With the help of a TE4 TECA electromyograph af double channel, and using surface electrodes Beckman type, the sternocleidomastoid muscle of both sides was studied on 30 young and healthy individuaIs from 19 through 28 years old, 15 being male and 15 female. Among these individuaIs, 6 presented respiratory pattern of the diaphragmatic type, 10 of the mixed type and 14 of the costal one. Electromyographic activities were found during the movements of: free extention of the head, free and counter-resistance head and protaction; heterolateral rotation of the head; homolateral bent of the head; free deep inspiration; deep inspiration only through the mouth; deep inspiration only through the nose; and abrupt deep inspiration. The movements were performed in the following positions: sitting, drosal decurnbent and pedaling an ergometric bucycle with 1 to drosal 2 kilo load and 25 to 30 Km/h speed for nearly 15 minutes
Mestrado
Anatomia
Mestre em Biologia e Patologia Buco-Dental
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Paulgerg-Muschiol, Larissa von [Verfasser]. "Wege in die Wohnungslosigkeit : eine qualitative Untersuchung / Larissa von Paulgerg-Muschiol." Siegen : Universitätsbibliothek der Universität Siegen, 2011. http://d-nb.info/101316878X/34.

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Muschiol, Daniel [Verfasser]. "Meiofauna in a chemosynthetic groundwater ecosystem: Movile Cave, Romania / Daniel Muschiol." Bielefeld : Universitätsbibliothek Bielefeld, 2009. http://d-nb.info/1036110915/34.

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Yu, Tung Fai. "Musculo-skeletal modelling and parameterisation in vivo." Thesis, University of Warwick, 2014. http://wrap.warwick.ac.uk/60564/.

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This thesis describes the development of an anatomically meaningful musculo-skeletal model of the human arm, incorporating two modified Hill muscle models representing the elbow flexor and extensor muscles. In vivo experimental methods to determine parameter values are presented. The stimulus for this work was to enable the prediction of movement, to support development of prostheses and orthoses such as Functional Electrical Stimulation (FES). A key problem in model based movement studies is that the passive parameter values in the Hill muscle models and the joint had not been experimentally determined in vivo. The result has been an inability for predictive models to generate realistic predictions of human movement dynamics. In the model, movement dynamics of the forearm was described using the Newton-Euler method, which was validated from analysis of physical pendulum. Structural identifiability analyses of the muscle models ensured that values for the model parameters could be uniquely determined from perfect noise free data. A novel experimental procedure termed the passive movement method is described, which exclusively parameterised the model’s passive components. Simulated model dynamics were fitted to measured movements of the freely swinging forearm under gravity. Model values were obtained on an individual subject basis. The average muscle model spring and damping constants for four healthy subjects were 143N/m and 1.73Ns/m respectively. Separately, the force/length characteristics of the muscles’ active component, the contractile element (CE), were obtained from measurements of isometric maximum voluntary contraction (MVC) at different elbow angles. The results for the five healthy subjects showed good agreement with results reported in the literature. A preliminary experiment was performed to predict elbow flexion movement under FES. An electrical stimulus that generated a specified isometric elbow flexion moment (10% of MVC) was applied to generate elbow flexion movement. Simulated FES arm movement was compared with the measured results. The simulated change in elbow angle did not agree with the measured data. A major cause for this was believed to be skin movement causing a change in the current path across the muscle fibres, thus affecting the force generated. The passive movement method described in this thesis filled an important chapter to fully parameterise musculo-skeletal models in vivo. Although in the FES movement experiment, simulated change in elbow angle generated by FES did not agree with measured data, the shape of the dynamic response in the fitted simulated movement showed good agreement with the measured FES movement.
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Grosso, Debora Bevilaqua. "Musculo vasto lateral obliquo correlações anatomo-clinicas." [s.n.], 1996. http://repositorio.unicamp.br/jspui/handle/REPOSIP/290928.

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Orientador: Fausto Berzin
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba
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Resumo: Trinta e duas coxas foram dissecadas com o objetivo de se estudar as duas porções do músculo vasto lateral e os respectivos ângulos de inserção na patela, bem como suas relações com as estruturas associadas: retináculo lateral e tracto iliotibial. De acordo com os resultados obtidos, o músculo vasto lateral divide se em duas porções: uma longa e proximal, o vasto lateral longo e outra oblíqua e distal, o vasto lateral oblíquo. O músculo vasto lateral oblíquo origina-se da linha áspera do fêmur e septo intermuscular lateral inserindo-se por tendão próprio, o qual dirige-se inferior e lateralmente ao músculo vasto lateral longo, unindo-se a este na borda superolateral da patela, freqüentemente unido à cápsula articular. As fibras distais do músculo vasto lateral oblíquo apresentaram-se interdigitadas no retináculo lateral e tracto iliotibial. A porção superficial do músculo vasto lateral oblíquo mediu em média 8,95cm e as porções distal e proximal do seu ventre muscular distaram respectivamente 2,2cm e 11, 15cm do epicôndilo lateral. Os ângulos de inserção na patela foram, em média, de 13,6 graus para o músculo vasto lateral longo e 50,4 graus para o músculo vasto lateral oblíquo. Através dos resultados, concluímos que o músculo vasto lateral é dividido em duas porções distintas: o músculo vasto lateral longo e o músculo vasto lateral oblíquo. O músculo vasto lateral oblíquo é um importante estabilizador dinâmico da patela e por apresentar suas fibras distais interdigitadas no retináculo lateral e tracto iliotibial confere à essas estruturas estabilizadoras estáticas u!l1 caráter dinâmico, além de exercer por sua angulação, um importante vetor de tração lateral da patela
Abstract: Thirty-two thigh were dissecated to study the two parts of the vastus lateralís and its respective angles of the patella insertion, as well as the relation with the two associated structures as lateral retinaculum and iliotibial tract. According to the results obtained the vastus lateralís muscle is divided into two parts: one long and p roxi mal part, (vastus lateralís longus) and another oblique and distal, (vastus lateralís oblíquos). The vastus lateralís oblíquos muscle originated from the rough line of the femur and lateral intermuscular septum, being inserted for a tendon that goes inferior and lateral to the vastus lateralís longus muscle, joining to it at the superior and lateral patella board, frequently joined to the articular capsule. The distal fibers of the vastus lateralís obliquos presents themselves interdigitated at the lateral retinaculum and iliotibial tract. The superficial part of the vastus lateralís oblíquos muscle measured 8,95cm on average and the distal and proximal parts of its muscle belly had a distance of 2,2cm and 11, 15cm respectively from the lateral epicondilo. The insertion angles at the patella were 13,6 degrees for the vastus lateraris longus muscle and 50,4 degrees for the vastus lateralís oblíquos muscle. From these results, we can conclude that vastus lateralís muscle is dividided into two distinct parts: the vastus lateralís longus muscle and the vastus lateralís oblíquos muscle. The vastus lateralis oblíquos muscle it is an important stabilizer of the patella and for presenting its fibers interdigitated at the lateral retinaculum and iliot~bial tract confers to these static stabilizers structures, dinamic features. Besides to exert an important lateral traction force of the patella , for its angulation
Mestrado
Periodontia
Mestre em Ciências
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Patrianova, Marcio Espindola. "Estudo histoquimico do musculo diafragma do coelho." [s.n.], 1999. http://repositorio.unicamp.br/jspui/handle/REPOSIP/289765.

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Orientador: Luiz Antonio de Lima Resende
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba
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Resumo: A histoquímica baseia-se em reações bem estabelecidas em química orgânica ou inorgânica, usadas para dar um produto visível à microscopia óptica. Este trabalho teve por objetivo estudo normativo do músculo diafragma de coelhas da raça NorfoIk inglesa. A porção costal do músculo diafragma foi estudada pela histoquímica, em diferentes reações, incluindo-se a reação do NADH-TR, com o objetivo de se determinar a distribuição histoquímica de fibras do tipo I, IIA e IIB. Dentre 1037 fibras estudadas, o porcentual de distribuição histoquímica observado foi de fibras tipo 1,57,3 %; tipo IIA, 19,2 %; tipo IIB, 23,4 %. Conforme o esperado, o músculo diafragma da coelha, por sua atividade contínua na respiração do animal, apresenta-se com grande proporção de fibras do tipo I, resistentes à fadiga
Abstract: The histochemistry came from well established organic and inorganic chemical reactions, used for observation of visible products on optic microscopie. This work had as objective the assestment of the normative histochemical data in the costal portion of the diaphragm muscle from Norfolk English rabbits. The muscle specimens were processed by different histochemial reactions, and the normal distribution of I, IIA and IIB muscle fibers were established from analysis of the NADH-TR reaction. From 1,037 muscle fibres counted, we found 57,3 % of the type I, 19,2 % of the type IIA and 23,4 % of the type IIB. These results are expected, because the diaphragm muscle has a continuous activity during all the life of the animals, and so, need a high proportion of the oxidative type I fibres, resistent to the fadigue
Mestrado
Biologia e Patologia Buco-Dental
Mestre em Odontologia
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Van, Den Abbeele Maxim. "Modélisation Musculo-Squelettique Personnalisée du Rachis Cervical." Thesis, Paris, ENSAM, 2018. http://www.theses.fr/2018ENAM0037.

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Dans le cadre du programme scientifique de chaire BiomecAM, la modélisation musculo-squelettique du rachis cervical répond à différents besoins: comprendre les mécanismes d’endommagement de cette structure fonctionnelle essentielle, améliorer la prévention des pathologies, aider à la conception de nouveaux dispositifs (orthèses ou implants) et planification de traitements orthopédiques et chirurgicaux. De grandes avancées ont été faites ces dernières années pour progresser vers la modélisation personnalisée: des approches innovantes pour générer des maillages en éléments finis efficaces, des moyens d’analyse quantitative in vivo pour personnaliser les propriétés mécaniques du disque intervertébral et du système musculaire, des premières modélisations pertinentes de la commande neuro-motrice d’activation musculaire.L’objectif de cette thèse est de s’appuyer sur ces avancées pour proposer une modélisation musculo squelettique personnalisée du rachis cervical intact, lésé et restauré chirurgicalement, dans le but de mieux comprendre les mécanismes de dégénération du rachis cervical et d’évoluer vers un outil de planification de traitements orthopédiques et chirurgicaux s’appuyant sur cette modélisation personnalisée
Within the context of the scientific program chaired by BiomecAM, the musculoskeletal modelling of the cervical spine responds to various needs: understanding the damage mechanisms to this functional and essential structure, augmenting the efficiency level of pathology prevention, contributing to the design of new medical devices (orthoses or implants) and enabling orthopaedic and surgical treatment planning. Strong advancements have been made during the recent past years to evolve towards personalised modelling: innovative finite element mesh generation methods, in vivo quantitative analysis techniques to personalise the assignment of material properties to the intervertebral disc and the muscular system and preliminary models incorporating muscle activation have been developed.The aim of this PhD project is to exploit these scientific advancements to evolve towards a personalised musculoskeletal model of the intact, degenerated and instrumented cervical spine, thus contributing to the understanding of the degeneration mechanisms of the cervical spine and offering a means of orthopaedic and surgical treatment planning
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Books on the topic "Muschio"

1

Tuckermann, Anja. Muscha. München: E. Klopp, 1994.

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Magnus, Enzensberger Hans. Mond und Muschel. Berlin: Aufbau-Verlag, 2000.

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Manfred, Dierks, and Muschg Adolf 1934-, eds. Adolf Muschg. Frankfurt am Main: Suhrkamp, 1989.

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Muschi e licheni: Racconti, memorie, personaggi. [Sestu] (Cagliari): Zonza, 2006.

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Parise, Goffredo. Veneto barbaro di muschi e nebbie. [Bologna]: Nuova Alfa, 1987.

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Feil, Erich. Musterschutzgesetz: (MuSchG 1990). Eisenstadt: Prugg, 1990.

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Hedenäs, Lars. Amblystegiaceae (Musci). Bronx, N.Y: Published for Organization for Flora Neotropica by The New York Botanical Garden, 2003.

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Dennis, D. J. The guns of Muschu. Crows Nest, NSW: Allen & Unwin, 2006.

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Watson, Ian. Aspects of homoeopathy: Musculo-skeletal problems. Kendal, Cumbria, England: Cutting Edge Publications, 1998.

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Maurus, Nigg Benno, and Herzog W. 1955-, eds. Biomechanics of the musculo-skeletal system. 2nd ed. Chichester: Wiley, 1999.

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Book chapters on the topic "Muschio"

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Hangay, George, Susan V. Gruner, F. W. Howard, John L. Capinera, Eugene J. Gerberg, Susan E. Halbert, John B. Heppner, et al. "Muscoid Larva." In Encyclopedia of Entomology, 2514. Dordrecht: Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6359-6_4732.

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Hangay, George, Susan V. Gruner, F. W. Howard, John L. Capinera, Eugene J. Gerberg, Susan E. Halbert, John B. Heppner, et al. "Muscid Flies." In Encyclopedia of Entomology, 2513. Dordrecht: Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6359-6_4730.

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Hoffmann, Anna-Janina. "Muschg, Adolf." In Kindlers Literatur Lexikon (KLL), 1. Stuttgart: J.B. Metzler, 2020. http://dx.doi.org/10.1007/978-3-476-05728-0_12598-1.

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Vedder, Björn. "Adolf Muschg." In Kindler Kompakt Schweizer Literatur, 196–200. Stuttgart: J.B. Metzler, 2016. http://dx.doi.org/10.1007/978-3-476-05517-0_49.

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Dierks, Manfred. "Muschg, Adolf." In Metzler Autoren Lexikon, 630–32. Stuttgart: J.B. Metzler, 1997. http://dx.doi.org/10.1007/978-3-476-03720-6_307.

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Ellis, Nadia. "Musculo-skeletal problems." In Acupuncture in Clinical Practice, 222–41. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4899-4545-7_13.

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Tyler, Philippa, and Asif Saifuddin. "Musculo-Skeletal Imaging." In European Surgical Orthopaedics and Traumatology, 3–62. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-34746-7_12.

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Arnold, June. "Musculo-skeletal Pain." In Geriatric Medicine, 71–87. London: Springer London, 1989. http://dx.doi.org/10.1007/978-1-4471-1646-2_6.

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Vedder, Björn. "Muschg, Adolf: Erzählungen." In Kindlers Literatur Lexikon (KLL), 1–3. Stuttgart: J.B. Metzler, 2020. http://dx.doi.org/10.1007/978-3-476-05728-0_12600-1.

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Vedder, Björn. "Muschg, Adolf: Kinderhochzeit." In Kindlers Literatur Lexikon (KLL), 1–2. Stuttgart: J.B. Metzler, 2020. http://dx.doi.org/10.1007/978-3-476-05728-0_12604-1.

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Conference papers on the topic "Muschio"

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Miller, Erick, and Joe Harkins. "Musculo-skeletal shape skinning." In ACM SIGGRAPH 2007 sketches. New York, New York, USA: ACM Press, 2007. http://dx.doi.org/10.1145/1278780.1278830.

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Moissenet, Florent, Laurence Cheze, and Raphaël Dumas. "Introduction of Contact Forces Minimization in the Musculo-Tendon Forces Optimization During Gait." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53650.

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Since joint contact forces can be measured using instrumented implants, they can be used to validate musculo-tendon and contact forces predicted by simulation. We propose in this study a new approach that introduces contact forces minimization in the musculo-tendon forces optimization during gait. We show that using a numerical trick, it can be possible to compute in a one-level optimization both musculo-tendon and contact forces. Moreover we show that taking into account contact forces in the optimization has a real impact on musculo-tendon forces computation.
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Moissenet, Florent, Laurence Cheze, and Raphaël Dumas. "Simultaneous Prediction of Musculo-Tendon, Joint Contact, Ligament and Bone Forces in the Lower Limb During Gait Using a One-Step Static Optimisation Procedure." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14455.

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Instrumented prostheses, by measuring joint contact forces during a movement, give nowadays a unique opportunity to validate the ability of musculo-skeletal models in predicting internal forces. In this study, a rigid multi-body musculo-skeletal model, allowing computing the musculo-tendon, joint contact, ligament and bone forces all together by static optimisation, using a weighted criterion, is presented. The results show that the musculo-tendon forces are generally in accordance with the envelopes of the main peaks of the subject’s EMG signals and that the amplitudes and patterns of the predicted joint contact, ligament and bone forces are in a good agreement with the measurements and with the literature. By allowing the introduction of other forces than the musculo-tendon forces in the static optimisation, this study opens new horizons in order to better model the human physiology (e.g., joint pain).
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Yamamura, Naoto, Shu Takagi, and Taishin Nomura. "Development of Multi-scale Musculo-Skeletal Simulator." In 2016 IEEE 16th International Conference on Bioinformatics and Bioengineering (BIBE). IEEE, 2016. http://dx.doi.org/10.1109/bibe.2016.34.

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Jones, Naveen, Manju Manuel, and Sreelal Pillai. "An embedded musculo-skeletal injury detection system." In 2016 International Conference on Emerging Technological Trends (ICETT). IEEE, 2016. http://dx.doi.org/10.1109/icett.2016.7873773.

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Haeufle, Daniel F. B., Michael Günther, and Syn Schmitt. "Musculo-Skeletal Models as Tools to Quantify Embodiment." In European Conference on Artificial Life 2015. The MIT Press, 2015. http://dx.doi.org/10.7551/978-0-262-33027-5-ch015.

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Pattnaik, Shrikant, and Jay Kim. "A Lumped Parameter Vibration Model Developed Based on a Realistic Kinematic Description of the Hand-Arm System." In ASME 2010 International Mechanical Engineering Congress and Exposition. ASMEDC, 2010. http://dx.doi.org/10.1115/imece2010-40466.

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Prolonged exposure of hand to vibration causes vascular, neurological and musculoskeletal abnormalities, which are collectively known as hand-arm vibration syndrome (HAVS). A significant number of construction workers, miners and even dentists are affected by HAVS. The precise mechanism or pathogenesis of the syndrome is still not clearly understood. Accurate analysis of hand-arm vibration response is very difficult due to the complexity of the hand-arm structure such as redundancy of the musculo-tendon unit, active participation from central nervous system, inherent non-linearity and heavy damping effect. Various types of lumped parameter models have been developed, typically by matching response characteristics of the model with the measurement. Not being based on the actual physics of the hand-arm, such a model has limited applications such as qualitative, relative analysis of the hand-arm response. A new lumped parameter model is developed in this work retaining as much actual kinematic characteristics of the hand and arm system as possible. The model includes descriptions of relevant musculo-tendon systems and the effect of the gripping force to enable calculation of the forces transmitted through the musculo-tendon system and joints.
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Seipel, Justin. "Towards Robustly Stable Musculo-Skeletal Simulation of Human Gait: Merging Lumped and Component-Based Modeling Approaches." In ASME 2012 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/detc2012-71473.

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The objective of work presented in this paper is to increase the center-of-mass stability of human walking and running in musculo-skeletal simulation. The approach taken is to approximate the whole-body dynamics of the low-dimensional Spring-Loaded Inverted Pendulum (SLIP) model of locomotion in the OpenSim environment using existing OpenSim tools. To more directly relate low-dimensional dynamic models to human simulation, an existing OpenSim human model is first modified to more closely represent bilateral above-knee amputee locomotion with passive prostheses. To increase stability further beyond the energy-conserving SLIP model, an OpenSim model based upon the Clock-Torqued Spring-Loaded-Inverted-Pendulum (CT-SLIP) model of locomotion is also created. The result of this work is that a multi-body musculo-skeletal simulation in Open-Sim can approximate the whole-body sagittal-plane dynamics of the passive SLIP model. By adding a plugin controller to the OpenSim environment, the Clock-Torqued-SLIP dynamics can be approximated in OpenSim. To change between walking and running, only one parameter representing the preferred period of a stride is changed. The result is a robustly stable simulation of the center-of-mass locomotion for both walking and running that could serve as a first step toward increasingly anatomically accurate and robustly stable musculo-skeletal simulations.
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Maleki, A., R. Shafaei, and A. Fallah. "Musculo-Skeletal Model of Arm for FES Research Studies." In 2008 Cairo International Biomedical Engineering Conference (CIBEC). IEEE, 2008. http://dx.doi.org/10.1109/cibec.2008.4786089.

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Christensen, S. T., K. Siebertz, M. Damsgaard, M. De Zee, J. Rasmussen, and G. Paul. "Human Seat Modeling Using Inverse Dynamic Musculo-Skeletal Models." In Digital Human Modeling for Design and Engineering Conference and Exhibition. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, 2003. http://dx.doi.org/10.4271/2003-01-2221.

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Reports on the topic "Muschio"

1

Hughes, Thomas C., John K. Flach, Mark P. Squire, James Whalen, Douglas J. Zimmer, Michael J. Patzek, and Britany A. Miller. Multi-UAV Supervisory Control Interface Technology (MUSCIT). Fort Belvoir, VA: Defense Technical Information Center, September 2012. http://dx.doi.org/10.21236/ada585659.

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