Journal articles on the topic 'Mus musculus'

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1

Jordá, Enrique García. "Mus musculus." Clinical and Translational Oncology 12, no. 9 (September 2010): 585–86. http://dx.doi.org/10.1007/s12094-010-0561-1.

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2

Markl, Hubert, and Günter Ehret. "Die Hörschwelle der Maus (Mus musculus)." Zeitschrift für Tierpsychologie 33, no. 3-4 (April 26, 2010): 274–86. http://dx.doi.org/10.1111/j.1439-0310.1973.tb02096.x.

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3

Vanlerberghe, F., B. Dod, P. Boursot, M. Bellis, and F. Bonhomme. "Absence of Y-chromosome introgression across the hybrid zone between Mus musculus domesticus and Mus musculus musculus." Genetical Research 48, no. 3 (December 1986): 191–97. http://dx.doi.org/10.1017/s0016672300025003.

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SummaryA cloned Y-specific sequence (Bishop et al. 1985) was used as a diagnostic probe to distinguish between Mus musculus domesticus and Mus musculus musculusY-chromosomes. Analysis of the RFLPs obtained with genomic DNA isolated from wild mice caught along the contact zone between M. m. domesticus and M. m. musculus in Bulgaria and Denmark showed that the Y-chromosome flow between the two semi-species is very limited. The degree of Y-chromosome penetration was compared with that of seven diagnostic autosomal loci and the mitochondrial DNA. Breeding experiments showed that the lack of Y-chromosome introgression from one semispecies to the other was not due to a major hybrid breakdown. The results suggest that the disruption of differentiated co-adapted gene systems could play a role in limiting Y-introgression.
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4

Mauron, Alex. "Mus musculus sapiens." Revue Médicale Suisse 11, no. 483 (2015): 1571. http://dx.doi.org/10.53738/revmed.2015.11.483.1571.

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5

Bishop, C. E., P. Boursot, B. Baron, F. Bonhomme, and D. Hatat. "Most classical Mus musculus domesticus laboratory mouse strains carry a Mus musculus musculus Y chromosome." Nature 315, no. 6014 (May 1985): 70–72. http://dx.doi.org/10.1038/315070a0.

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6

Neff, Ellen P. "Mus musculus ad astra." Lab Animal 46, no. 11 (November 2017): 429–33. http://dx.doi.org/10.1038/laban.1364.

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7

Kotenkova, Elena V., Alexander V. Osadchuk, and Svetlana I. Lyalyukhina. "Precopulatory isolating mechanisms between the house and mound-building mouse." Acta Theriologica 34 (August 10, 1989): 315–24. http://dx.doi.org/10.4098/at.arch.89-31.

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8

Dubin, R. A. "Functional comparison of the Mus musculus molossinus and Mus musculus domesticus Sry genes." Molecular Endocrinology 9, no. 12 (December 1, 1995): 1645–54. http://dx.doi.org/10.1210/me.9.12.1645.

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9

Dubin, R. A., P. Coward, Y. F. Lau, and H. Ostrer. "Functional comparison of the Mus musculus molossinus and Mus musculus domesticus Sry genes." Molecular Endocrinology 9, no. 12 (December 1995): 1645–54. http://dx.doi.org/10.1210/mend.9.12.8614401.

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10

Stopková, R., P. Stopka, K. Janotová, and P. L. Jedelský. "Species-specific Expression of Major Urinary Proteins in the House Mice (Mus musculus musculus and Mus musculus domesticus)." Journal of Chemical Ecology 33, no. 4 (February 28, 2007): 861–69. http://dx.doi.org/10.1007/s10886-007-9262-9.

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11

Fieldhouse, Dan, and G. Brian Golding. "Evolutionary rate variation within Mus APRT." Genome 39, no. 5 (October 1, 1996): 909–13. http://dx.doi.org/10.1139/g96-114.

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Rodents are thought to have relatively high rates of evolution, twice as fast as the rates for mammals in other orders. However, the uniformly high rates of evolution inferred for the order Rodentia from Mus musculus and Rattus norvegicus are not consistently found for other rodent species. Using a maximum likelihood phylogenetic algorithm (DNAML), we show here that Mus spicilegus has a fivefold different rate of evolution in 1100 bp around the adenine phosphoribosyltransferase gene (APRT) since its divergence from a common ancestor with Mus musculus. A greater than threefold difference in rates is also found in a comparison of the number of evolutionary events directly detected from the APRT sequences of these two closely related Mus species. The evolutionary events can be directly detected, since M. spicilegus, M. musculus, and the four rodent outgroup species used to determine the ancestral sequence are so closely related. One of the major differences between M. spicilegus and M. musculus that might affect evolutionary rate is the degree of commensalism with man. The Mus species therefore provide a useful model for testing various hypotheses for the causes of rate variations between genes, and possibly, between lineages. Key words : rate, variation, rodent, Mus spicilegus, Mus musculus.
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12

de Frutos, C., A. P. López-Cardona, N. Fonseca Balvís, R. Laguna-Barraza, D. Rizos, A. Gutierrez-Adán, and P. Bermejo-Álvarez. "Spermatozoa telomeres determine telomere length in early embryos and offspring." REPRODUCTION 151, no. 1 (January 2016): 1–7. http://dx.doi.org/10.1530/rep-15-0375.

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Offspring telomere length (TL) has been correlated with paternal TL, but the mechanism for this parent of origin-specific inheritance remains unclear. The objective of this study has been to determine the role of spermatozoa TL in embryonic telomere lengthening by using two mouse models showing dimorphism in their spermatozoa TL: Mus musculus vs Mus spretus and old vs young Mus musculus. Mus spretus spermatozoa displayed a shorter TL than Mus musculus. Hybrid offspring exhibited lower TL compared with Mus musculus starting at the two-cell stage, before the onset of telomerase expression. To analyze the role of spermatozoa telomeres in early telomere lengthening, we compared the TL in oocytes, zygotes, two-cell embryos and blastocysts produced by parthenogenesis or by fertilization with Mus musculus or Mus spretus spermatozoa. TL was significantly higher in spermatozoa compared with oocytes, and it increased significantly from the oocyte to the zygote stage in those embryos fertilized with Mus musculus spermatozoa, but not in those fertilized with Mus spretus spermatozoa or produced by parthenogenesis. A further increase was noted from the zygote to the two-cell stage in fertilized Mus musculus embryos, whereas hybrid embryos maintained the oocyte TL. Spermatozoa TL shortened with age in Mus musculus and the offspring from young males showed a significantly higher TL compared with that fathered by old males. These significant differences were already noticeable at the two-cell stage. These results suggest that spermatozoa telomeres act as a guide for telomerase-independent telomere lengthening resulting in differences in TL that persist after birth.Free Spanish abstract: A Spanish translation of this abstract is freely available at http://www.reproduction-online.org/content/151/1/1/suppl/DC1.
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13

BOŽÍKOVÁ, EVA, PAVEL MUNCLINGER, KATHERINE C. TEETER, PRISCILLA K. TUCKER, MILOŠ MACHOLÁN, and JAROSLAV PIÁLEK. "Mitochondrial DNA in the hybrid zone between Mus musculus musculus and Mus musculus domesticus: a comparison of two transects." Biological Journal of the Linnean Society 84, no. 3 (March 9, 2005): 363–78. http://dx.doi.org/10.1111/j.1095-8312.2005.00440.x.

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Lyalyukhina, Svetlana, Elena Kotenkova, Wiera Walkowa, and Krystyna Adamczyk. "Comparison of craniological parameters in Mus musculus musculus Linnaeus, 1758 and Mus hortulanus Nordmann, 1840." Acta Theriologica 36 (March 18, 1991): 95–107. http://dx.doi.org/10.4098/at.arch.91-6.

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15

Kunieda, Tetsuo, and Yutaka Toyoda. "Nucleotide sequence of mouse Sry gene is different between Y chromosomes originating from Mus musculus musculus and Mus musculus domesticus." Genomics 13, no. 1 (May 1992): 236–37. http://dx.doi.org/10.1016/0888-7543(92)90234-j.

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16

Drews, Sandra, and Milena Lehmann. "Kastration der männlichen Farbmaus (Mus musculus)." kleintier konkret 18, S 01 (March 27, 2015): 24–28. http://dx.doi.org/10.1055/s-0035-1547401.

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Bianchi, Marzia, Maria Elisabetta Clementi, Bruno Maras, Maria Eugenia Schininà, Manuela Bozzi, Bruno Giardina, and Andrea Brancaccio. "Recombinant expression of Mus musculus myoglobin." Protein Expression and Purification 29, no. 2 (June 2003): 265–71. http://dx.doi.org/10.1016/s1046-5928(03)00067-6.

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18

Schellinck, Heather. "Measuring Olfactory Processes in Mus musculus." Behavioural Processes 155 (October 2018): 19–25. http://dx.doi.org/10.1016/j.beproc.2017.08.009.

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19

Searle, Jeremy B., Paul M. Jamieson, İslam Gündüz, Mark I. Stevens, Eleanor P. Jones, Chrissen E. C. Gemmill, and Carolyn M. King. "The diverse origins of New Zealand house mice." Proceedings of the Royal Society B: Biological Sciences 276, no. 1655 (September 30, 2008): 209–17. http://dx.doi.org/10.1098/rspb.2008.0959.

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Molecular markers and morphological characters can help infer the colonization history of organisms. A combination of mitochondrial (mt) d -loop DNA sequences, nuclear DNA data, external measurements and skull characteristics shows that house mice ( Mus musculus ) in New Zealand and its outlying islands are descended from very diverse sources. The predominant genome is Mus musculus domesticus (from western Europe), but Mus musculus musculus (from central Europe) and Mus musculus castaneus (from southern Asia) are also represented genetically. These subspecies have hybridized to produce combinations of musculus and domesticus nuclear DNA coupled with domesticus mtDNA, and castaneus or musculus mtDNA with domesticus nuclear DNA. The majority of the mice with domesticus mtDNA that we sampled had d -loop sequences identical to two haplotypes common in Britain. This is consistent with long-term British–New Zealand cultural linkages. The origins of the castaneus mtDNA sequences widespread in New Zealand are less easy to identify.
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20

Musolf, Kerstin, Frauke Hoffmann, and Dustin J. Penn. "Ultrasonic courtship vocalizations in wild house mice, Mus musculus musculus." Animal Behaviour 79, no. 3 (March 2010): 757–64. http://dx.doi.org/10.1016/j.anbehav.2009.12.034.

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21

Le Roy, Isabelle, Pierre L. Roubertoux, Laure Jamot, Fatima Maarouf, Sylvie Tordjman, Stéphane Mortaud, Caroline Blanchard, Benoit Martin, Pascale-Valérie Guillot, and Vincent Duquenne. "Neuronal and behavioral differences between Mus musculus domesticus (C57BL/6JBy) and Mus musculus castaneus (CAST/Ei)." Behavioural Brain Research 95, no. 1 (September 1998): 135–42. http://dx.doi.org/10.1016/s0166-4328(97)00218-0.

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22

ITO, Tsuyoshi, Kimiyuki TSUCHIYA, Susumu OSAWA, Hideshi SHIBATA, and Naotoshi KANDA. "Mapping of rRNA Gene Loci in the Mice, Mus musculus molossinus (Japan) and Mus musculus musculus (Russia) by Double Color FISH." Journal of Veterinary Medical Science 70, no. 9 (2008): 997–1000. http://dx.doi.org/10.1292/jvms.70.997.

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23

Pratama, Edo Legianto, Tuti Heiriyani, and Riza Adrianoor Saputra. "POTENSI BIJI JARAK PAGAR SEBAGAI RODENTISIDA ALAMI." Jurnal Ilmu-Ilmu Pertanian Indonesia 23, no. 2 (December 24, 2021): 98–105. http://dx.doi.org/10.31186/jipi.23.2.98-105.

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[JATROPHA SEED POTENTIAL AS A NATURAL RODENTICIDE]. The controlling of rat's pest attacks often use chemical control that adversely affects non-target animals and leaves a residue for the environment. One of the recommended controls is to use natural rodenticides derived from jatropha seeds and do not harm non-target animals that are environmentally friendly. This research aims to determine the interaction and the best combination of bait mixed with jatropha seeds on the death of Mus musculus, as well as the type of bait and the best dose of jatropha seeds on the death of Mus musculus. The design in this study used a completely randomized design consisting of two factors, the first factor was the bait and the second factor was the dose of jatropha seeds. The results showed that there was an interaction between the type of bait and the dose of jatropha seeds on the amount of feed consumed by Mus musculus. The combination of bait type and dose of jatropha seeds that was best for the mortality of Mus musculus was found in the treatment of rice flour with 3.0 g of jatropha seeds, cornflour with 3.0 g of jatropha seeds, and fish meal with 3.0 g of jatropha seeds. The best dose of jatropha seeds in reducing the bodyweight of Mus musculus, accelerating the time of death, and increasing the percentage of death was 3.0 g of jatropha seeds with an average decrease in body weight of Mus musculus reaching 75%, and the fastest death for five days, and able to kill 100% of Mus musculus.
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24

Orth, Annie, Theophilus Adama, Waheedud Din, and François Bonhomme. "Hybridation naturelle entre deux sous-espèces de souris domestique, Mus musculus domesticus et Mus musculus castaneus, près du lac Casitas (Californie)." Genome 41, no. 1 (February 1, 1998): 104–10. http://dx.doi.org/10.1139/g97-109.

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The house mouse Mus musculus is a polytypic species, distributed worldwide, with three main subspecies: M. m. musculus in the North-East of Eurasia, M. m. castaneus in South-East Asia, and M. m. domesticus in Europe, the Near-East, and Africa. This last subspecies may also be found in Australia and the Americas, where it was brought by European colonization. Previous studies, however, have shown the presence of specific antiviral determinants of Asian origin in a mouse population at Lake Casitas, California. In this study, an analysis of the variability at 35 enzyme loci demonstrates the hybrid nature of this Californian population intermediate between M. m. castaneus and M. m. musculus. Restriction fragment length polymorphisms of two fragments of the mitochondrial DNA also confirm unambiguously the presence of two types of matrilines in comparable frequencies in our sample. Nevertheless, the study of a subspecies-specific Y chromosome microdeletion in the Zfy2 gene reveals only theM. m. domesticus haplotype at Lake Casitas, a phenomenon comparable with the one observed in other hybrid zones of the M. musculus complex. These findings testify once more that genetic exchanges between subspecies inside the broader M. musculus gene pool are still possible.
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Vanlerberghe, Flavie, Pierre Boursot, Josette Catalan, Svestoslav Gerasimov, François Bonhomme, B. Atanassov Botev, and Louis Thaler. "Analyse génétique de la zone d'hybridation entre les deux sous-espèces de souris Mus musculus domesticus et Mus musculus musculus en Bulgarie." Genome 30, no. 3 (June 1, 1988): 427–37. http://dx.doi.org/10.1139/g88-072.

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The hybrid zone between the two subspecies of mice Mus musculus domesticus and Mus musculus musculus, which has been studied extensively in Denmark, crosses Europe to the Black Sea through the Alps and the Balkans. Two hundred and seventy-nine animals were captured in 22 localities along a transect across the Balkans. The animals were characterized for seven diagnostic nuclear loci by protein electrophoresis and by restriction pattern analysis of their mitochondrial DNA. The nuclear data show a sharp transition between the two subspecies, most of the variations in allele frequencies (from 0.9 to 0.1) occurring within a 36-km section of the transect. The introgression varies from one locus to the other and is more pronounced, in terms of distance, in M. m. musculus territory. Mitochondrial DNA introgression is important but occurs in one direction only, i.e. from M. m. musculus to M. m. domesticus, while a cytoplasmic transfer from M. m. domesticus to M. m. musculus has been reported. A previous study showed that no Y chromosome introgression occurs. The different behaviour of these three types of markers could be due to the interaction between selection against hybrid genomes and meiotic recombination. Objectively, it would appear that the genes that can introgress are neutral or nearly so and have been separated from deleterious genes they were linked to by recombination. This could explain the differential introgression between autosomal loci. The mitochondrial and Y chromosomes undergo no or very little recombination and each is transmitted as a whole. Their degree of introgression is thus indicative of the intensity of selection resulting from the amount of functional differentiation between the two taxa, which seems to be strong for the Y chromosome and weak for mitochondrial DNA. We propose that the asymmetry of nuclear introgression is due to different population structures. As M. m. musculus is relatively less structured, the rapid spreading of introgressed genes would be favoured. Such a scheme, however, can hardly account for the unidirectionality of the mitochondrial flow, which could be due to sex-dependant behaviour.Key words: mice, hybrid zone, introgression, enzyme polymorphism.
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Faridz, Achmad Salman, Budi Wicaksono, Erry Gumilar Dachlan, and Widjiati Widjiati. "Penurunan Progesterone-Induced Blocking Factor (PIBF) Sebagai Penanda Preeklampsia." Majalah Obstetri & Ginekologi 24, no. 1 (July 21, 2017): 13. http://dx.doi.org/10.20473/mog.v24i1.2756.

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Tujuan: Membandingkan kadar PIBF serum dan berat plasenta pada model preeklampsia.Bahan dan Metode: Penelitian cross sectional yang dilakukan pada 16 Mus musculus bunting normal dan 16 Mus musculus bunting yang diberikan anti Qa-2 untuk membentuk suatu model preeklampsia. Kemudian dilakukan terminasi pada hari ke 16 kebuntingan dan dilakukan pemeriksaan kadar PIBF serum dengan metode ELISA serta pengukuran berat plasenta.Hasil: Didapatkan penurunan kadar PIBF serum pada Mus musculus model preeklampsia dibandingkan kontrol (33,21±29,36 ng/ml vs 105,76±59,69 ng/ml; p<0,05). Tidak ada perbedaan berat plasenta Mus musculus model preeklampsia dibandingkan kontrol (97,75±50,74 mg vs 116,09±44,45 mg; p>0,05). Tidak didapatkan hubungan antara kadar PIBF serum dengan berat plasenta.Simpulan: Penurunan kadar PIBF serum dapat dijadikan sebagai penanda kejadian preeklampsia. Penurunan kadar PIBF serum diduga berhubungan dengan kelainan plasenta pada preeklampsia.
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Noriko, Nita, Riris Lindiawati Puspitasari, and Adita Surya Doeana. "Pengaruh Pakan Tepung Cannalina terhadap Pertumbuhan Mus musculus." JURNAL Al-AZHAR INDONESIA SERI SAINS DAN TEKNOLOGI 3, no. 1 (December 5, 2017): 54. http://dx.doi.org/10.36722/sst.v3i1.185.

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<p><em>Abstrak</em> – <strong>Gizi buruk merupakan salah satu masalah kesehatan masyarakat di Indonesia, sedangkan kecukupan zat gizi dibutuhkan untuk pertumbuhan. Upaya untuk memenuhi kebutuhan nutrisi terus dilakukan salah satunya dengan mencari pangan alternatif. Pada penelitian ini bahan makanan yang digunakan adalah tepung Cannalina yang merupakan kombinasi umbi ganyong merah (<em>Canna edulis</em> Kerr) dan <em>Spirulina</em> (<em>Spirulina platensis</em>). Tujuan penelitian ini adalah untuk memperoleh informasi mengenai pengaruh pemberian pakan tepung Cannalina terhadap pertumbuhan, kadar glukosa dan kolesterol darah <em>M. musculus</em>.</strong><strong> </strong><strong> Metode penelitian adalah eksperimental terhadap 60 ekor <em>M. musculus</em> (mencit) yang dibagi atas 3 kelompok. Kelompok kontrol yaitu yang diberi pakan makanan pelet komersial, kelompok mencit yang makanannya merupakan 50% pelet komersil dan 50% tepung Cannalina, serta kelompok mencit yang makanannya 100% tepung Cannalina. Hasil penelitian menunjukkan pakan tepung Cannalina 50% tidak memberikan respon positif terhadap pertambahan berat badan, panjang badan dan berat otak normal <em> M. musculus</em>. Akan tetapi dapat mempertahankan kadar normal yang cenderung rendah untuk glukosa yaitu 120 mg/dl dan kolesterol yaitu 155 mg/dl. Pemberian tepung Cannalina 100% memberikan efek letal pada <em>M. musculus</em> pada hari ke-4 pengamatan. Tepung Cannalina 50% dan 100% berpotensi untuk menurunkan berat badan, glukosa dan kolestrol darah.</strong> </p><p> </p><p><strong><em>Kata kunci</em></strong><em> </em> - <em>Gizi buruk, kesehatan masyarakat, pangan alternatif , tepung Cannalina, pertumbuhan </em></p><p><em>Abstract</em> – <strong>Malnutrition is one of public health problem in Indonesia. Nutritional adequacy is needed for growth. The efforts is looking for alternative food. In this research food material are Cannalina flour which is combination of red <em>Canna edulis and Spirulina platensis</em>. The aim of the reseach was to obtain information of granting feed Cannalina flour on the growth, blood glucose, and cholesterol level of <em>Mus musculus</em>. The research method was experimental to 60 of <em>M. musculus</em> were divided into 3 groups. The control group of <em>M. musculus</em> that were fed a commercial food. the second group are <em>M. musculus</em> that were fed a 50% of commercial food and 50% of Cannalina flour, and the third group are <em>M. musculus</em> that were fed a 100% of Cannalina flour. The research shows that Cannalina Flour 50% could not give a positive response to increase the weight, body length, and weight brain of <em>M. musculus</em>. Otherwise Cannalina flour 50% can maintain a blood glucose and cholesterol level in normal levels that tend more lower than control. Result giving of Cannalina flour 50% for blood glucose is 120mg/dl and cholesterol level is 155 mg/dl. The giving of Cannalina flour 100% have lethal effect to <em>M. musculus </em>since day 4 experiment<em>. </em>Cannalina flour 50% and 100% are potential to lose weight gain, blood glucose, and cholesterol level.</strong></p><p> </p><strong><em>Keywords</em></strong><em> – malnutrion, public health, alternative food, Cannalina flour, growth</em>
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Naeem, Khadija, Naveed Ahmad, and Asmatullah. "Cytotec Induced Embryotoxicity in Developing Mus musculus." Asian-Australasian Journal of Animal Sciences 23, no. 10 (August 20, 2010): 1282–90. http://dx.doi.org/10.5713/ajas.2010.90636.

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29

Priante, Ettore, Edoardo Pietropoli, Elisabetta Piva, Gianfranco Santovito, Sophia Schumann, and Paola Irato. "Cadmium–Zinc Interaction in Mus musculus Fibroblasts." International Journal of Molecular Sciences 23, no. 19 (October 9, 2022): 12001. http://dx.doi.org/10.3390/ijms231912001.

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This work aimed to evaluate the effects of zinc (Zn) relating to cadmium (Cd)-induced toxicity and the role played by MTF-1. This transcription factor regulates the expression of genes encoding metallothioneins (MTs), some Zn transporters and the heavy chain of γ-glutamylcysteine synthetase. For this reason, two cell lines of mouse fibroblasts were used: a wild-type strain and a knockout strain to study the effects. Cells were exposed to complete medium containing: (1) 50 μM ZnSO4 (Zn), (2) 1 μM CdCl2 (Cd 1), (3) 2 μM CdCl2 (Cd 2), (4) 50 μM ZnSO4 + 1 μM CdCl2 (ZnCd 1) and (5) 50 μM ZnSO4 + 2 μM CdCl2 (ZnCd 2) for 4, 18 and 24 h. Following exposure, cell viability, the intracellular content of metals, glutathione (GSH) and MT and the gene expression of the two isoforms of MT was evaluated. The results obtained suggest that a lower Cd content in the co-treatments is responsible for the protection offered by Zn due to the probable competition for a common transporter. Furthermore, Zn determines an increase in GSH in co-treatments compared to treatments with Cd alone. Finally, the MTF-1 factor is essential for the expression of MT-1 but not of MT-2 nor probably for the heavy chain of γ-glutamylcysteine synthetase.
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30

Klink, Karin B., and Georg M. Klump. "Duration discrimination in the mouse (Mus musculus)." Journal of Comparative Physiology A 190, no. 12 (October 5, 2004): 1039–46. http://dx.doi.org/10.1007/s00359-004-0561-0.

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Chauvin, Theodore R., Tao Liu, Carrie Nicora, Fang Xie, Feng Yang, David Camp, Richard Smith, and Kenneth P. Roberts. "The Sperm Maturation Proteome of Mus musculus." Biology of Reproduction 85, Suppl_1 (July 1, 2011): 575. http://dx.doi.org/10.1093/biolreprod/85.s1.575.

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32

Palomo, L. Javier, J. Mario Vargas, and F. Javier Pozueta. "Superpositions of regular moults in Mus musculus." Acta Theriologica 39 (December 20, 1994): 379–88. http://dx.doi.org/10.4098/at.arch.94-44.

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33

Alzubaidi, Amar, Nahla A. Al-Bakri, and Ateeq M. J. Alarami. "Glomerulogenesis and Histomorphometeric in Mus musculus Embryo." Ibn AL-Haitham Journal For Pure and Applied Sciences 36, no. 2 (April 18, 2023): 14–21. http://dx.doi.org/10.30526/36.2.3000.

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In mammals, the kidneys originate in an embryo from the mesoderm through three excretory organs, namely: Pronephros, Mesonephros, and Metanephros. After the formation of Metanephros is completed, the kidneys begin to form nephrogenesis through mesenchymal cells located at the tip of the ureteric bud, that contribute in the formation of glomerulus and Renal tubules. The stages of glomerulus formation in the embryo of albino mice at the age of 14 to 19 days of gestation were studied. It was obtained after the sacrifice of the expectant mother and the kidneys were excised from the embryos and fixed using Aqueous Bouin's solution, Microscopic slices with a thickness of 6 microns were then made in a paraffin method and were photographed by a camera for microscopic imaging. Histological measurements were performed on them using the program IMAGE J program and analyzed statistically using the SPSS program. Results of the current study showed the presence of five stages of glomerulus formation, namely, the renal vesicle, which represents the first stage in the formation of the nephron and glomerulus. This is followed by the Comma shape stage, S-shaped stage, Capillary loop stage and finally the Mature glomerulus. This is surrounded by a capsule, known as Bowman’s capsule being part of the Malpighian or Renal corpuscle. The statistical analysis showed that there were significant differences between the average diameters of the glomerular development stages, and that the mature glomerulus was larger in diameter than the rest of the stages. The study aims to determine the stages of glomerulus formation and histologically measure its diameter in the embryo of a Mus musculus.
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BÍMOVÁ, BARBORA, ROBERT C. KARN, and JAROSLAV PIÁLEK. "The role of salivary androgen-binding protein in reproductive isolation between two subspecies of house mouse: Mus musculus musculus and Mus musculus domesticus." Biological Journal of the Linnean Society 84, no. 3 (March 9, 2005): 349–61. http://dx.doi.org/10.1111/j.1095-8312.2005.00439.x.

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35

Čížková, Dagmar, Stuart J. E. Baird, Jana Těšíková, Sebastian Voigt, Ďureje Ľudovít, Jaroslav Piálek, and Joëlle Goüy de Bellocq. "Host subspecific viral strains in European house mice: Murine cytomegalovirus in the Eastern (Mus musculus musculus) and Western house mouse (Mus musculus domesticus)." Virology 521 (August 2018): 92–98. http://dx.doi.org/10.1016/j.virol.2018.05.023.

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36

Greene-Till, Rhonda, Yingping Zhao, and Stephen C. Hardies. "Gene flow of unique sequences between Mus musculus domesticus and Mus spretus." Mammalian Genome 11, no. 3 (March 2000): 225–30. http://dx.doi.org/10.1007/s003350010041.

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37

West, John D., John D. Ansell, and Jean H. Flockhart. "Expression of glucose phosphate isomerase in interspecific hybrid(Mus musculus ×Mus caroli)." Developmental Genetics 12, no. 6 (1991): 403–14. http://dx.doi.org/10.1002/dvg.1020120605.

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38

Agrienvi. "Firlianty, Hermansyah, Windarina Samosir." Agrienvi: Jurnal Ilmu Pertanian 13, no. 02 (October 8, 2020): 45–50. http://dx.doi.org/10.36873/aev.v13i02.1773.

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This study aims to know the effectivity of snakehead (Channa micropeltes) gel extract on the burns healing ofrat (Mus musculus). It was carried out for 4 months, September 2018 to January 2019. The study employed anexperimental method of Complete Randomized Design with 4 treatmnets and 3 replications. Treatment A wascontrol, B used 1.5% gel extract of C. micropeltes, C used 3 %, and D used 4.5%, respectively. Results revealed thatin day-4, 8 and 12 the administration of gel extract of C. micropeltes gave significant effect on the burns healing of rat(Mus musculus) (Fcalc.> Ftab., 0.05).Keywords : gel extract, Channa micropeltes, rat Mus musculus, burns healing
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Agrienvi. "Firlianty, Hermansyah, Windarina Samosir." Agrienvi, Jurnal Ilmu Pertanian 13, no. 02 (February 3, 2020): 45–50. http://dx.doi.org/10.36873/aev.v13i02.661.

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ABSTRACTThis study aims to know the effectivity of snakehead (Channa micropeltes) gel extract on the burns healing ofrat (Mus musculus). It was carried out for 4 months, September 2018 to January 2019. The study employed anexperimental method of Complete Randomized Design with 4 treatmnets and 3 replications. Treatment A wascontrol, B used 1.5% gel extract of C. micropeltes, C used 3 %, and D used 4.5%, respectively. Results revealed thatin day-4, 8 and 12 the administration of gel extract of C. micropeltes gave significant effect on the burns healing of rat(Mus musculus) (Fcalc.> Ftab., 0.05).Keywords : gel extract, Channa micropeltes, rat Mus musculus, burns healing.
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40

Primiani, Cicilia. "Potensi Genistein pada Sistem Reproduksi Mencit sebagai Penyusunan Bahan Ajar Fisiologi Reproduksi." Belantika Pendidikan 1, no. 1 (November 4, 2019): 37–44. http://dx.doi.org/10.47213/bp.v1i1.20.

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Penelitian ini bertujuan untuk menguji pengaruh genistein terhadap sistem reproduksi mencit jantan (Mus musculus). Memanfaatkan hasil penelitian pengaruh genistein terhadap sistem reproduksi mencit jantan (Mus musculus) sebagai bahan untuk menyusun bahan ajar mata kuliah fisiologi. Penelitian ini menggunakan pendekatan kuantitatif eksperimental, yang rancangannya mengikuti Rancangan Acak Kelompok. Variabel bebas adalah dosis genistein 0 mg/g, 0,0035 mg/g, 0,0042 mg/g, dan 0,0049 mg/g. Hasil penelitian menunjukkan bahwa ada pengaruh genistein pada sistem reproduksi mencit (Mus musculus). Genistein yang diberikan dengan dosis 0,0035 mg/g; 0,0042 mg/g; dan 0,0049 mg/g berpengaruh terhadap jumlah sel germinal dalam tubulus seminiferus testis, morfologi dan viabilitas spermatozoa.
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Zala, Sarah M., Doris Reitschmidt, Anton Noll, Peter Balazs, and Dustin J. Penn. "Sex-dependent modulation of ultrasonic vocalizations in house mice (Mus musculus musculus)." PLOS ONE 12, no. 12 (December 13, 2017): e0188647. http://dx.doi.org/10.1371/journal.pone.0188647.

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Nishioka, Yutaka, and Estelle Lamothe. "The Mus musculus musculus type Y chromosome predominates in Asian house mice." Genetical Research 50, no. 3 (December 1987): 195–98. http://dx.doi.org/10.1017/s0016672300023697.

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SummaryUsing a mouse Y chromosomal repetitive sequence that differentiates between the Mus musculus musculus type Y chromosome and the M. m. domesticus type Y chromosome, we studied the Y chromosome in M. m. molossinus, M. m. castaneus and M. m. subspecies specimens recently trapped in Japan, Taiwan and China as well as Asian mice maintained at the Jackson Laboratory and Litton Bionetics. Here we report that the M. m. musculus type Y chromosome predominates in Asian house mice and that Japanese mice maintained at some laboratories may not represent typical M. m. molossinus.
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Afifah, Andi Retno, Sri Wahyu, Sri Wahyuni Gayatri, Indah Lestari Daeng Kanang, and Rezky Putri Indarwati Abdullah. "Pengaruh Pemberian Ekstrak Buah Pare Terhadap Penurunan Kadar Glukosa Darah Pada Mencit (Mus musculus)." Indonesian Journal of Health 1, no. 03 (June 25, 2021): 163–69. http://dx.doi.org/10.33368/inajoh.v1i03.66.

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Diabetes melitus (DM) mengacu pada sindrom hiperglikemia akibat berbagai penyebab. Dewasa ini, banyak masyarakat yang mengkonsumi buah pare sebagai obat diabetes. Karena menurut pemikiran mereka, rasa pahit nya dapat menetralisir kadar gula dalam darah. Momordica charantia (Buah Pare) adalah tanaman yang digunakan sebagai sayuran dan obat tradisional dengan aktivitas buah hipoglikemik. Momordica charantia (Buah Pare) mengandung senyawa seperti insulin yang disebut charantin yang memiliki sifat anti diabetes dan membantu mengurangi kadar gula darah. Penelitian ini bertujuan mengetahui pengaruh pemberian ekstrak buah pare (Momordica charantia) terhadap penurunan kadar glukosa darah pada mencit (Mus musculus). Jenis penelitian ini menggunakan Literature Review dengan desain Narrative Review. Ekstrak buah pare (Momordica charantia) dapat menurunkan kadar glukosa darah pada mencit (Mus musculus) diabetes dengan konsentrasi 100 mg/kgBB, 250 mg/kgBB dan 400 mg/kgBB. Ekstrak buah pare (Momordica charantia) dengan konsentrasi 400 mg/KgBB dapat menurunkan glukosa darah yang hampir setara dengan pemberian metformin pada mencit (Mus musculus) yang diabetes. Ekstrak buah pare (Momordica charantia) dapat menurunkan kadar glukosa darah pada mencit (Mus musculus) diabetes. Namun lebih efektif pada dosis 400 mg/Kg.
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Rumtal, Heryl, Rosdiana Ngitung, and A. Mu’nisa A. Mu’nisa. "Pengaruh Pemberian Tepung Tempe terhadap Kadar Kolesterol Total Darah Mencit (Mus musculus) Hiperkolesterol." bionature 20, no. 2 (December 8, 2019): 116. http://dx.doi.org/10.35580/bionature.v20i2.11281.

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Abstract. This research is experimental which aims to determine the effect of giving Tempe Flour to total blood cholesterol concentration of hypercholesterol mice (Mus musculus). The independent variable of this research Tempe Flour while the dependent variable is the total blood cholesterol concentration of mice (Mus musculus). The subject of this research is 25 male ICR strain (Imprinting Control Region) mice with 3 months age divided 5 treatment groups which are normal group, hypercholesterol group, giving of tempe flour at dose of 10 g / day / BB (P1), 20 g / days / BB (P2) and 25 g / day / BB (P3). Tempe flour is given after the giving of cholesterol feed. All mices blood cholesterol concentration were check after the time of treatment. The result is analyz by using ANOVA with Ducan test. The result of this research show that the giving of Tempe Flour affected the decrease of blood cholesterol concentration of mice (Mus musculus) in dose of 10 g/day/BB,20 g/day/BB and 25 g/day/BB. Dose of 25 g/day/BB showed an effective dose for lowering cholesterol in the research. Keywords: tempe flour, cholesterol, hypercholesterol, mencit (Mus musculus)
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Lestari, Ima Fitria, Junieta Fara Syafirah, and Dita Amanda Deviani. "UJI EFEK ANALGESIK EKSTRAK DAUN SIRIH HIJAU BANYUWANGI (Piper betle L.) PADA MENCIT PUTIH JANTAN (Mus musculus)." Jurnal Riset Kefarmasian Indonesia 5, no. 1 (January 31, 2023): 156–66. http://dx.doi.org/10.33759/jrki.v5i1.351.

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The content of flavonoid compounds in betel leaf is used as a protection as analgesic. The purpose of this study was to test the analgesic effects of Banyuwangi green betel leaf extract (Piper betle L.) on male white mice (Mus musculus). The doses of green betel leaf ethanol extract that were used were 4.696 mg, 9.392 mg and 18.784 mg and the positive control were mefenamic acid. The test animals used in this study were white male mice (Mus musculus) that were adapted for about 3 days in experimental environmental conditions. Based on the results of the study, the analgesic effect test of green betel leaf extract (Piper betle L.) can provide analgesic effectiveness on mice (Mus musculus). Ethanol extracts of green betel leaf (Piper betle L.) at doses of 4.696 mg/kgBW were able to provide a good analgesic effect with good responses to white male mice (Mus musculus). The percentage of analgesic power that was close to the percentage of analgesic power of the gold standard which is 69.23%.
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46

Andi Retno Afifah, Sri Wahyu, Sri Wahyuni Gayatri, Indah Lestari Daeng Kanang, Rezky Putri Indarwati Abdullah, Andi Farid Abdullah, and Nur Fatimah Sirajuddin. "Pengaruh Pemberian Ekstrak Buah Pare (Momordica Charantia) Terhadap Penurunan Kadar Glukosa Darah Pada Mencit (Mus Musculus)." Fakumi Medical Journal: Jurnal Mahasiswa Kedokteran 2, no. 3 (April 1, 2022): 224–30. http://dx.doi.org/10.33096/fmj.v2i3.158.

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Diabetes melitus (DM) mengacu pada sindrom hiperglikemia akibat berbagai penyebab. Dewasa ini, banyak masyarakat yang mengkonsumi buah pare sebagai obat diabetes. Karena menurut pemikiran mereka, rasa pahitnya dapat menetralisir kadar gula dalam darah. Momordica charantia (Buah Pare) adalah tanaman yang digunakan sebagai sayuran dan obat tradisional dengan aktivitas buah hipoglikemik. Momordica charantia (Buah Pare) mengandung senyawa seperti insulin yang disebut charantin yang memiliki sifat anti diabetes dan membantu mengurangi kadar gula darah. Penelitian ini bertujuan mengetahui pengaruh pemberian ekstrak buah pare (Momordica charantia) terhadap penurunan kadar glukosa darah pada mencit (Mus musculus). Jenis penelitian ini menggunakan Literature Review dengan desain Narrative Review. Ekstrak buah pare (Momordica charantia) dapat menurunkan kadar glukosa darah pada mencit (Mus musculus) diabetes dengan konsentrasi 100 mg/kgBB, 250 mg/kgBB dan 400 mg/kgBB. Ekstrak buah pare (Momordica charantia) dengan konsentrasi 400 mg/KgBB dapat menurunkan glukosa darah yang hampir setara dengan pemberian metformin pada mencit (Mus musculus) yang diabetes. Ekstrak buah pare (Momordica charantia) dapat menurunkan kadar glukosa darah pada mencit (Mus musculus) diabetes. Namun lebih efektif pada dosis 400 mg/KgBB
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47

Johnson, Gerald G., and Verne M. Chapman. "Altered Turnover of Hypoxanthine Phosphoribosyltransferase in Erythroid Cells of Mice Expressing Hprt a and Hprt b Alleles." Genetics 116, no. 2 (June 1, 1987): 313–20. http://dx.doi.org/10.1093/genetics/116.2.313.

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ABSTRACT We have previously shown that mice expressing Hprt a allele(s) have erythrocyte hypoxanthine phosphoribosyltransferase (HPRT) levels that are approximately 25-fold (Mus musculus castaneus) and 70-fold (Mus spretus) higher than in mice that express the Hprt b allele (Mus musculus domesticus; C57BI/6J; C3H/HeHa), and that these differences in erythrocyte HPRT levels are due to differences in the turnover rates of the HPRT A and B proteins as reticulocytes mature to erythrocytes. We show here that: (1) the taxonomic subgroups of the genus Mus are essentially monomorphic for the occurrence of either the Hprt a or the Hprt b allele, with Hprt a being common in the aboriginal species (M. spretus, Mus hortulanus and Mus abbotti) and in several commensal species (Mus musculus musculus, M. m. castaneus, Mus musculus molossinus), while Hprt b is common in feral M. m. domesticus populations as well as in all inbred strains of mice tested; (2) in all these diverse Mus subgroups there is a strict association of Hprt a with high and Hprt b with low levels of erythrocyte HPRT; and, (3) the association between the occurrence of the Hprt a allele and elevated erythrocyte HPRT levels is retained following repeated backcrosses of wild-derived Hprt a allele(s) into the genetic background of inbred strains of mice with the Hprt b allele. Collectively, these observations indicate that the elevated and low levels of erythrocyte HPRT are specified by differences in the Hprt a and b structural genes. Since evidence indicates that Hprt a and b encode HPRT proteins which differ in primary structure, we infer that the structure of HPRT is an important factor in determining its sensitivity to turnover in mouse erythroid cells. Hprt a and b may provide a useful system of "normal" allelic gene products for identifying factors that participate in protein turnover during mouse reticulocyte maturation.
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48

Zakri, Dwika Febriana, Hijratul Hasanah, Vishtari Salsabilla, Yuni Ahda, and Yusni Atifah. "PENGARUH PEMBERIAN EKSTRAK DAUN SIRIH (Piper betle L.) TERHADAP SPERMATOGENESIS Mus musculus." Jurnal Ilmu Kedokteran dan Kesehatan 10, no. 10 (November 12, 2023): 2973–77. http://dx.doi.org/10.33024/jikk.v10i10.10902.

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Abstrak: Pengaruh Pemberian Ekstrak Daun Sirih (Piper Betle L.) Terhadap Spermatogenesis Mus musculus. Di Indonesia, permasalahan yang terjadi saat ini adalah peningkatan jumlah penduduk yang sangat tinggi, sehingga perlu dikembangkan suatu metode kontrasepsi untuk pria yang aman, efektif dan mudah diaplikasikan. Daun sirih (Piper betle L.) mengandung fenol, alkaloid dan tanin yang telah digunakan sebagai antifertilitas alami secara tradisional. Tujuan penelitian ini adalah untuk mengetahui pengaruh ekstrak daun sirih terhadap spermatogenesis dan motilitas mencit putih (Mus musculus). Penelitian ini bersifat eksperimental dengan rancangan acak lengkap. Subyek penelitian adalah 15 ekor mencit putih (Mus musculus) yang dibagi menjadi 3, kelompok 1 tidak diberi perlakuan apapun dan dijadikan sebagai kontrol negatif dan kelompok 2-3 diberi perlakuan dosis yang berbeda yaitu, sebanyak 0,3 mg dan 0.6 mg pada mencit yang memiliki berat lebih kurang 25 gr. Perlakuan dilakukan selama 15 hari. Pengamatan spermatogenesis diukur berdasarkan morfologi dan keaktifan gerak dari sperma pada epididimisnya. Hasil penelitian menunjukkan bahwa semakin banyak dosis yang diberikan, maka tingkat keaktifan gerak spermanya semakin rendah, dan bentuk morfologinya tidak sempurna. Sehingga, dapat kita simpulkan bahwa zat aktif pada daun sirih dapat mempengaruhi proses spermatogenesis pada mencit putih (Mus musculus) dengan menghambat pembentukan spermatozoa serta mempengaruhi tingkat keaktifan motilitas. Sehingga disarankan bahwa ekstrak daun sirih dapat dipertimbangkan untuk digunakan sebagai kontrasepsi alami untuk pria.
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49

León, V. A., J. Fraschina, and M. Busch. "Population subdivision of house mice (Mus musculus) in an agrarian landscape: consequences for control." Canadian Journal of Zoology 88, no. 5 (May 2010): 427–35. http://dx.doi.org/10.1139/z10-014.

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In Argentinean agroecosystems, house mice ( Mus musculus L., 1758) show a discontinuous distribution, with high abundances in farms but scarce abundance in crop fields. In our study area, the abundance of M. musculus could be affected by their movements among farms. We hypothesize that (1) M. musculus do not move among farms versus (2) M. musculus do move among farms. Furthermore, based on our second hypothesis, M. musculus move actively (hypothesis 2.1) or passively by human transport (hypothesis 2.2). Based on hypothesis 1, we predict that genetic subdivision will exist among farms and that genetic divergence will be independent of geographic distance. Based on hypothesis 2.1, genetic differentiation will be correlated with geographic distance. Based on hypothesis 2.2, genetic subdivision will be absent, or genetic differentiation will be related to human movements. We examined genetic variation among farms (n = 15) using five microsatellite loci and tracked the movements of 36 individuals from five farms with fluorescent powders. Populations of M. musculus showed genetic differentiation at both farm and shed scales. Genetic and geographic distances were significantly correlated. There was no evidence of passive movements of M. musculus. The movements of 36 M. musculus within farms, tracked with fluorescent powder, were short. According to these results, hypothesis 2.1 is favoured.
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Ehlers, Bernhard, Judit Küchler, Nezlisah Yasmum, Güzin Dural, Sebastian Voigt, Jonas Schmidt-Chanasit, Thomas Jäkel, et al. "Identification of Novel Rodent Herpesviruses, Including the First Gammaherpesvirus of Mus musculus." Journal of Virology 81, no. 15 (May 16, 2007): 8091–100. http://dx.doi.org/10.1128/jvi.00255-07.

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ABSTRACT Rodent herpesviruses such as murine cytomegalovirus (host, Mus musculus), rat cytomegalovirus (host, Rattus norvegicus), and murine gammaherpesvirus 68 (hosts, Apodemus species) are important tools for the experimental study of human herpesvirus diseases. However, alphaherpesviruses, roseoloviruses, and lymphocryptoviruses, as well as rhadinoviruses, that naturally infect Mus musculus (house mouse) and other Old World mice are unknown. To identify hitherto-unknown rodent-associated herpesviruses, we captured M. musculus, R. norvegicus, and 14 other rodent species in several locations in Germany, the United Kingdom, and Thailand. Samples of trigeminal ganglia, dorsal root ganglia, brains, spleens, and other organs, as well as blood, were analyzed with a degenerate panherpesvirus PCR targeting the DNA polymerase (DPOL) gene. Herpesvirus-positive samples were subjected to a second degenerate PCR targeting the glycoprotein B (gB) gene. The sequences located between the partial DPOL and gB sequences were amplified by long-distance PCR and sequenced, resulting in a contiguous sequence of approximately 3.5 kbp. By DPOL PCR, we detected 17 novel betaherpesviruses and 21 novel gammaherpesviruses but no alphaherpesvirus. Of these 38 novel herpesviruses, 14 were successfully analyzed by the complete bigenic approach. Most importantly, the first gammaherpesvirus of Mus musculus was discovered (Mus musculus rhadinovirus 1 [MmusRHV1]). This virus is a member of a novel group of rodent gammaherpesviruses, which is clearly distinct from murine herpesvirus 68-like rodent gammaherpesviruses. Multigenic phylogenetic analysis, using an 8-kbp locus, revealed that MmusRHV1 diverged from the other gammaherpesviruses soon after the evolutionary separation of Epstein-Barr virus-like lymphocryptoviruses from human herpesvirus 8-like rhadinoviruses and alcelaphine herpesvirus 1-like macaviruses.
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