Journal articles: 'Murraya'

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Saini, Satish Chand. "Murraya koenigii." IOSR Journal of Pharmacy and Biological Sciences 7, no. 6 (2013): 15–18. http://dx.doi.org/10.9790/3008-0761518.

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Rathore, Jitendra Singh, and Umesh Gilhotra. "Evaluation of Antiasthmatic Activity of Murraya Koenigii L. Leaves." Research in Pharmacy and Health Sciences 3, no. 2 (May 15, 2017): 285–93. http://dx.doi.org/10.32463/rphs.2017.v03i02.07.

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The present investigation was designed to evaluate the anti-asthmatic activity of ethanolic extract of Murraya Koenigii Leaves in experimental animals. Murraya Koenigii Leaves was evaluated for anti-histaminic activity using isolated Guinea pig tracheal chain preparation, histamine induced Bronchoconstriction in Guinea pig and milk induced leucocytosis in mice. Ethanolic extract of Murraya Koenigii Leaves oral dose 400mg/kg body weight significantly inhibited dose dependent contraction of Guinea pig tracheal chain produced by histamine and also showed significant protection by prolonging PreConvulsion Dyspnoea time (PCT) in guinea pigs. Murraya Koenigii Leaves was evaluated by milk induced leucocytosis in mice showed significant decreased of total leukocyte count. Thus, Murraya Koenigii Leaves showed anti-allergic activity against histamine hence possesses potential role in the treatment of asthma.

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Phatak, Rohan S., Chitra C. Khanwelkar, Somnath M. Matule, Kailas D. Datkhile, and Anup S. Hendre. "Antihyperglycemic Activity of Murraya koenigii Leaves Extract on Blood Sugar Level in Streptozotocin-Nicotinamide Induced Diabetes in Rats." Biomedical and Pharmacology Journal 12, no. 2 (June 28, 2019): 597–602. http://dx.doi.org/10.13005/bpj/1679.

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The effects of Murraya koenigii leaves are very less studied in streptozotocin-nicotinamide (STZ-NA) induced diabetes rat model, in spite of several studies reported its antidiabetic effects in alloxan and STZ induced diabetes. The present study was undertaken to assess the effects of Murraya koenigii leaves extract on the blood sugar level (BSL) of STZ-NA diabetic rats. Experimental diabetes was induced by STZ injection intraperitoneally (i. p) after 30 min of NA injection i. p in all groups apart from normal control group. Group I (normal control) and Group II (diabetic control) rats received distilled water. Group III rats treated Metformin, Group IV and Group V rats treated Murraya koenigii aqueous extract and Murraya koenigii methanolic extract respectively. BSL and body weights of rats were measured at each week of the period of 28 days. Our results indicate that oral administration of Murraya koenigii reduces BSL significantly compared with the diabetic group. No weight loss was observed in all groups. The findings of the present study suggest that Murraya koenigii is proven as anti-diabetic agent in diabetic rats.

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Mou, Feng-Juan, Xiu Hu, Bui Thu Ha, and Nguyen Manh Cuong. "Taxonomic revision of Bergera J.Koenig ex L. (Rutaceae) based on the molecular phylogeny and morphology." European Journal of Taxonomy 860 (March 1, 2023): 141–80. http://dx.doi.org/10.5852/ejt.2023.860.2057.

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Several phylogenetic studies have revealed that Murraya s. lat. is not monophyletic, suggesting that it should be split into two genera, namely Murraya s. str. and Bergera J.Koenig ex L. Here, the genus Bergera is comprehensively revised based on molecular and morphological data. The genus consists of 11 species in total, including all species previously placed in Murraya sect. Bergera and an additional species previously placed in Murraya sect. Murraya. Ten new combinations are proposed, namely Bergera alternifolia (Kurz) F.J.Mou comb. nov., B. crenulata (Turcz.) F.J.Mou comb. nov., B. euchrestifolia (Hayata) F.J.Mou comb. nov., B. glabra (Guillemin) F.J.Mou comb. nov., B. kwangsiensis (C.C.Huang) F.J.Mou comb. nov., B. macrophylla (C.C.Huang) F.J.Mou comb. nov., B. microphylla (Merr. & Chun) F.J.Mou comb. nov., B. siamensis (Craib) F.J.Mou comb. nov., B. stenocarpa (Drake) F.J.Mou comb. nov., and B. tetramera (C.C.Huang) F.J.Mou comb. nov. An identification key of the 11 species and morphological descriptions are provided, as well as illustrations of diagnostic characteristics. Phylogenetic relationships of the species in Bergera are discussed.

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Suman, Rajesh Kumar, Ipseeta Ray Mohanty, Manjusha K. Borde, Y. A. Deshmukh, Anurag Pathak, Arun Kumar Adhikari, and H. K. Singh. "Evaluation of antidiabetic efficacy of Murraya koenigii on Streptozotocin induced diabetes in experimental rats." International Journal of Basic & Clinical Pharmacology 8, no. 8 (July 23, 2019): 1906. http://dx.doi.org/10.18203/2319-2003.ijbcp20193200.

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Background: The medicinal plant Murraya koenigii shown to have a wide variety of pharmacological activities (hypoglycemic and hypolipidemic). Objective of this study is the present study was designed to evaluate Antidiabetic and Hypolipidemic property of Murraya koenigii in experimentally induced diabetes in rats.Methods: Experimental diabetes was produced with single dose of Streptozotocin (STZ): 45 mg/kg IP. The rats were randomly allocated in various groups for 37 days. After the confirmation of diabetes on 7th day (>200 mg/dl), hydroalcoholic extract of Murraya koenigii (500 mg/kg) was administered orally to experimental rats from day 7th day and continued for 37 days thereafter. Various antidiabetic (Glucose, HbA1C), metabolic (Lipid profile), safety (pancreatic lipase, Creatinine, SGPT, Histopathology of Liver and Kidney) were evaluated in various group.Results: Efficacy of Murraya koenigii was observed on various parameter of diabetes. Administration of STZ resulted in a significant decrease in diabetic changes (increase in blood glucose, HbA1C), altered lipid profile (p<0.01) in the Control group rats as compared to sham group. Murraya koenigii treatment demonstrated significant antidiabetic indicated by restoration of blood glucose, HbA1C level (p<0.01) compared to Control group. In addition, Murraya koenigii also documented hypolipidemic property of test drug. As per biochemical assessment of Pancreatic lipase, Serum creatinine, SGPT and Histopathological report, the test drug reduce the pancreatic, liver and renal marker and also showed safe to pancreas, Liver and kidney. The histopathological assessment of the liver and kidney confirmed the biochemical findings.Conclusions: The study concluded that the Murraya koenigii possess antidiabetic efficacy.

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Husna, Fauzul, Franciscus Suyatna, Wawaimuli Arozal, and Erni Poerwaningsih. "Anti-Diabetic Potential of Murraya Koenigii (L.) and its Antioxidant Capacity in Nicotinamide-Streptozotocin Induced Diabetic Rats." Drug Research 68, no. 11 (May 25, 2018): 631–36. http://dx.doi.org/10.1055/a-0620-8210.

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Abstract Aim and Objective The present study aims to investigate whether the antihyperglycemic effect of Murraya koenigii is mediated by antioxidant properties and insulin mimetic effect. Methods Thirty Spraque-Dawley rats were induced hyperglycemia by streptozotocin and nicotinamide (STZ-NA). The STZ-NA diabetic rats were treated with an ethanolic extract of Murraya koenigii 200 mg/kg b.w and 400 mg/kg b.w. One group was treated with glibenclamide (1 mg/kg b.w). After the administration of Murraya koenigii extract and glibenclamide for four weeks, the rats were sacrificed. Blood and organ samples were collected under a fasting condition. The body weight and blood glucose levels were measured. Hepatic enzymes were determined using a commercial kit, protein levels were estimated by Bradford’s method, and plasma insulin was assayed by an ELISA kit. Malondialdehyde (MDA) and reduced glutathione (GSH) levels were estimated by the TBA-Wills method and Ellman’s method, respectively. Results Ethanolic extract of Murraya koenigii showed a significant reduction in blood glucose level at both doses, 200 and 400 mg/kg b.w. In addition, Murraya koenigii exhibited a profound antioxidant effect with decreased MDA level and increased GSH level, particularly at the 200 mg/kg b.w. and significantly decreased the HOMA-IR index. Conclusions The present study reveals that Murraya koenigii possesses antidiabetic activity and antioxidant effects on STZ-NA induced diabetes mellitus.

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Notriawan, Doni, Gustria Ernis, Risky Hadi Wibowo, Reza Pertiwi, and Tessa Rianti Malau. "Aktivitas Antibakteri Nanopartikel Perak Hasil Green Synthesis Menggunakan Ektrak Kulit Buah Kemuning (Murraya Paniculata (L) Jack)." BIOEDUSAINS:Jurnal Pendidikan Biologi dan Sains 3, no. 2 (December 30, 2020): 140–44. http://dx.doi.org/10.31539/bioedusains.v3i2.1850.

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Antibacterial activity using silver nanoparticles synthesized using Murraya Paniculata (L) rinds extract has been carried out. This study aims to determine the antibacterial activity of green synthesized silver nanoparticles using Murraya Paniculata (L) rinds extract. Silver nanoparticles were synthesized by reacting AgNO3 with water extract of the Murraya Paniculata (L) rinds. Green synthesized silver nanoparticles were tested for antibacterial activity using Escherichia coli ATCC 8739. Silver nanoparticles synthesized using Murraya Paniculata (L) rinds extract were characterized using a UV-Vis spectrophotometer to confirm the formation of silver nanoparticles. The UV-Vis spectrophotometer results showed the formation of silver nanoparticles which was indicated by an absorption around 400-450 nm. The antibacterial activity test results of silver nanoparticles showed a strong inhibitory activity. Keywords: Green Synthesis, Silver Nanoparticles, Antibacterial, Echerichia Coli

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Salwe, Kartik J., Mirunalini R., Jervin Mano, and K. Manimekalai. "Hepatoprotective and antioxidant activity of Murraya Koenigii leaves extract against paracetamol induced hepatotoxicity in Rats." International Journal of Basic & Clinical Pharmacology 6, no. 6 (May 23, 2017): 1274. http://dx.doi.org/10.18203/2319-2003.ijbcp20172044.

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Background: Many pharmacological substances are known to cause hepatic injuries and paracetamol is one out of them. This study was carried out to investigate the hepatoprotective and antioxidant activity of hydroalcoholic extract of Murraya koenigii leaves in paracetamol induced hepatotoxicity in Rats.Methods: Experimental animal used in this study were 30 healthy male albino Wistar rats of 10 to 12 wks weighing 180 ± 20 g. After acclimatization for a period of one week, the rats were randomized into five groups of six rats each. Safety profile and dose selection of extract was evaluated using acute toxicity studies. Five groups named as Normal control, Paracetamol induced hepatotoxicity, Murraya koenigii leaves extract 100 mg/kg bw, Murraya koenigii leaves extract 200 mg/kg bw and Silymarin group respectively. The doses of drugs and plant extract was calculated based on the body weight of each animal and administered orally for 7 days. On 8th day rats were sacrificed and blood samples were collected by cardiac puncture for biochemical estimation of biochemical parameters. Then abdomen was opened to get liver sample for antioxidant activity and histopathology.Results: Acute toxicity studies showed the non-toxic nature of Murraya koenigii leaves extract upto dose of 2000 mg/kg body weight. Murraya koenigii leaves extract in both doses showed a significant drop in the mean levels of AST, ALT, ALP, TP and TB when compared with toxic control group. The higher dose was found better than lower dose. Silymarin was found better than both the doses. Murraya koenigii leaves extract in both doses significantly reduced the TBARS level when compared to toxic control group. The activities of GSH, SOD and CAT in liver were significantly lower in Paracetamol induced hepatotoxicity rats compared to control rats. Murraya koenigii leaves extract at both doses showed a significant increase in GSH, SOD and CAT. The higher dose was found better than lower dose. Silymarin was found better than both the doses. Histopathology of Liver biopsy with higher dose of Murraya koenigii leaves extract showed reduced periportal inflammation with mild hepatic venous congestion and Silymarin treated rats showed no periportal inflammation with mild congestion in few central veins.Conclusions: Murraya koenigii leaves extract possesses significant Hepatoprotective property; this may be due to antioxidant activity. Further studies are required to determine the exact mechanism.

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Wiyogo, Illona Okvita, Pepy Dwi Endraswari, and Yuani Setiawati. "Antibacterial Activity of Ethanol Extract of Kemuning (Murraya Paniculata) Against Klebsiella pneumoniae ESBL by In Vitro Test." Indonesian Journal of Tropical and Infectious Disease 9, no. 2 (August 31, 2021): 101. http://dx.doi.org/10.20473/ijtid.v9i2.9328.

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Klebsiella pneumoniae Extended-spectrum β-lactamase (ESBL) was one of the microorganism that cause nosocomial infection which resistant to beta-lactams antibiotics. Orange Jessamine (Murraya paniculata) was traditional medicine which believed has antibacterial components, such as: ﬂ avonoids, alkaloids, essential oils, coumarins, terpenoids, tannins, and saponins. In the previous studies, there was antibacterial activity in ethanolic extract of Murraya paniculata againsts E.coli, K.pneumoniae, S.typhi, E.faecalis, P.aeruginosa, S.ﬂ exneri, S.aureus, and S.sonneii with concentration 200 mg/ mL. There has not experiment about ethanolic extract of Murraya paniculata against Klebsiella pneumoniae ESBL yet. The aim of this study was to ﬁ nd out the in vitro antibacterial activity of ethanol extracts of Murraya Paniculata against Klebsiella pneumoniae ESBL Broth dilution method with concentration 200 mg/mL, 100 mg/mL, 50 mg/mL, 25 mg/mL, 12,5 mg/mL, 6,25 mg/mL, and 3,125 mg/mL were used for the determination of the Minimal Inhibitory Concentration (MIC). While the Minimal Bacterial Concentration (MBC) was assessed using streaking method in Nutrient Agar Plate. The highest concentration in this study was obtained from 100 g of Murraya paniculata leaves dissolved in 500 mL of 40% ethanol. The study was carried out 4 times replication. At the time of the sterility test extract, germ growth appeared on Nutrient Agar Plate media, so the extract was ﬁ ltered before being used for research. After incubation at 37 °C for 24 hours, growth of bacterial colonies on all agar plates was observed. The concentration of the ethanol extract of Murraya Paniculata (200 mg/mL) did not inhibit the growth of Klebsiella pneumoniae ESBL. The ethanol extracts of Murraya paniculata in concentration 200 mg/mL had no antibacterial activity against Klebsiella pneumoniae ESBL.

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Damsteegt, V. D., E. N. Postnikova, A. L. Stone, M. Kuhlmann, C. Wilson, A. Sechler, N. W. Schaad, R. H. Brlansky, and W. L. Schneider. "Murraya paniculata and Related Species as Potential Hosts and Inoculum Reservoirs of ‘Candidatus Liberibacter asiaticus’, Causal Agent of Huanglongbing." Plant Disease 94, no. 5 (May 2010): 528–33. http://dx.doi.org/10.1094/pdis-94-5-0528.

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Huanglongbing (HLB), considered to be the most serious insect-vectored bacterial disease of citrus, is transmitted in nature by the Asian citrus psyllid Diaphorina citri and the African citrus psyllid Trioza erytreae. D. citri was discovered in southern Florida in 1998 and the HLB disease in 2005. Both have become established throughout citrus-producing areas of Florida. Murraya species are widely grown in southern Florida as ornamental hedges and are readily colonized by D. citri vectors. Colonies of D. citri, isolates of ‘Candidatus Liberibacter asiaticus’ from Taiwan and Florida, and the Murraya species were established in the BSL-3 biosecurity facility at Fort Detrick. In controlled inoculation experiments, D. citri transmitted ‘Ca. L. asiaticus’ into M. paniculata (34/36 plants) and M. exotica (22/23 plants), but not into Bergera (Murraya) koenigii. Disease symptoms rarely developed in Murraya plants; however, positive infections were determined by conventional and real-time polymerase chain reaction (PCR). Back-inoculations of ‘Ca. L. asiaticus’ from M. paniculata to Madam Vinous sweet orange resulted in disease development in 25% of the inoculated plants. Considerable variability was observed in infection rates, titer, and persistence of ‘Ca. L. asiaticus’ in infected Murraya.

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Siswidiasari, Arifani, and Dewa Putu Agus Wahyu Erawan. "AKTIVITAS LARVASIDA EKSTRAK ETANOL DAUN KEMUNING (Murraya paniculata JACK) TERHADAP LARVA Aedes aegypti." MIDWINERSLION : Jurnal Kesehatan STIKes Buleleng 5, no. 2 (September 30, 2020): 430. http://dx.doi.org/10.52073/midwinerslion.v5i2.220.

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Introduction: A research had been carried out to analyze the larvicidal activity of the ethanol extract of kemuning leaves (Murraya paniculata (L.) Jack.) against Aedes aegypti L. larvae. Method: The research began with extracting yellow leaves (Murraya paniculata (L.) Jack.) With a modified maceration method using 80% ethanol solvent until a thick extract is obtained, then a preliminary test is carried out to obtain LC5 and LC95 so that 5 concentrations of yellow leaf extract (Murraya paniculata (L.) Jack.) can be obtained which can be used as a real larvicide test. The actual larvicide test was carried out with 7 treatments, namely 1 negative control using Tween 80, 5 test treatments namely 1000 bpj yellow leaf extract, 3000 bpj, 5000 ppm, 7000 ppm and 9000 ppm and 1 positive control using Temephos 2 bpj. Observation of the test results was carried out after 24 hours by counting the number of larvae deaths in each treatment group. Result: The data obtained were analyzed by using probit analysis and obtained LC90 of yellow leaf extract (Murraya paniculata (L.) Jack.) which is 8330,291 bpj. The results showed that the yellow leaf extract (Murraya paniculata (L.) Jack.) was effective as a larvicidal activity with LC5 of 1000 bpj and LC95 of 9000 bpj.

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Iskandar, Sofyan Reza, Prayoga Fery Yuniarto, and Yuni Sulistyowati. "Analysis Of Vitamin C Levels Of Curry Leaf Ethanol Extract (Murraya Koenigii L. Spreng) By Uv-Vis Spectrophotometry." Al Makki Health Informatics Journal 1, no. 2 (November 29, 2023): 50–59. http://dx.doi.org/10.57185/hij.v1i2.7.

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Curry leaves (Murraya Koenigii L. Spreng) are a source of vitamin A, vitamin B, vitamin C, vitamin B2, calcium and iron in large quantities. Vitamin C serves to improve the body's immune system by stimulating the production of interferon (Winarsi, 2007). Determination of vitamin C levels in curry leaves (Murraya koenigii L. Spreng) has never been carried out so the following research was carried out to understand vitamin C levels for curry leaves (Murraya koenigii L. Spreng) by UV-Vis spectrometric method. The type of research applied is laboratory experiments. The population was curry leaves (Murraya koenigii L. Spreng) while samples were curry leaves (Murraya koenigii L. Spreng) which were dried in the sun and then extracted using 96% ethanol solvent. The results obtained with KMnO4 are positive, with iodine reagents being negative, and with ammonium molybdate being positive. Positive here means that vitamin C is obtained in the ethanol extract of curry leaves, and negative vice versa. Obtained an average vitamin C level of 3,962 ppm in curry leaf ethanol extract. It was concluded in this study that 96% ethanol extract in curry leaves contains vitamin C. And UV-Vis spectrophotometry succeeded in proving the levels of vitamin C contained in curry leaf plants.

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Esser, Hans-Joachim. "Taxonomic notes on the Rutaceae of Thailand." Thai Forest Bulletin (Botany) 49 (2021): 27–31. http://dx.doi.org/10.20531/tfb.2021.49.1.02.

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Nomenclatural problems with the name Atalantia simplicifolia are discussed, and it is shown that A. roxburghiana, often used for it, is illegitimate. Formerly part of Murraya, Bergera is recognized as separate genus for Thailand. Murraya siamensis is reduced to a synonym of Bergera koenigii.

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Esser, Hans-Joachim. "Taxonomic notes on the Rutaceae of Thailand." Thai Forest Bulletin (Botany) 49 (2021): 27–31. http://dx.doi.org/10.20531/tfb2021.49.1.02.

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Nomenclatural problems with the name Atalantia simplicifolia are discussed, and it is shown that A. roxburghiana, often used for it, is illegitimate. Formerly part of Murraya, Bergera is recognized as separate genus for Thailand. Murraya siamensis is reduced to a synonym of Bergera koenigii.

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Saha, C., and B. K. Chowdhury. "Carbazoloquinones from Murraya koenigii." Phytochemistry 48, no. 2 (May 1998): 363–66. http://dx.doi.org/10.1016/s0031-9422(97)01135-7.

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Desoky, E. "Phytosterols from Murraya exotica." Phytochemistry 40, no. 6 (December 1995): 1769–72. http://dx.doi.org/10.1016/0031-9422(95)00821-n.

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ASTUTI, INGGIT PUJI, and RUGAYAH RUGAYAH. "A NEW SPECIES OF MURRAYA FROM CYCLOPS MOUNTAIN, PAPUA, INDONESIA." REINWARDTIA 15, no. 2 (December 22, 2016): 111. http://dx.doi.org/10.14203/reinwardtia.v15i2.2944.

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ASTUTI, I. P. & RUGAYAH. 2016. A new species of Murraya from Cyclops Mountain, Papua, Indonesia. Reinwardtia 15(2): 111 –114. — A living collection of Bogor Botanic Gardens, planted in plot XXIV.A.192-192a and originated from Kemiri Said Nature Reserve, Cyclops Mountain in Papua collected by Lugrayasa (LG 1352), is described and illustrated as a new species, namely Murraya cyclopensis Astuti & Rugayah. The species is closely related to Murraya paniculata (L.) Jack, in vegetative and flower structures, but differ in the presence of indumentum on twig, rachis and petiole, smaller size of flowers, red globose fruits, and orbicular seeds covered by densely short hairs and red aril.

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Anish, Anusha, Sherena Padinjarevattom Abdulkadir, Annamala Panthapulakkil Theru, and Mukkadan Joseph Kurian. "Anti-mutagenic Activity of Oxycarotenoid-rich Extracts Isolated from Coriandrum Sativum and Murraya koenigii." Asian Pacific Journal of Cancer Biology 5, no. 4 (December 7, 2020): 147–52. http://dx.doi.org/10.31557/apjcb.2020.5.4.147-152.

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Introduction: Edible and medicinal plants contain active principles that can act as antimutagens, and hence their intake may be useful for human cancer prevention. Green leafy vegetables are important sources of carotenoids which possess antioxidant, anti-inflammatory and antimutagenic properties. Objective: To study the antimutagenic activity of oxycarotenoid-rich extracts isolated from Coriandrum sativum (coriander leaves) and Murraya koenigii (curry leaves). Methods: Oxycarotenoid-rich extracts isolated from Coriandrum sativum (coriander leaves) and Murraya koenigii (curry leaves) were investigated for antimutagenic activity in vitro by Ames test using Salmonella typhimurium strains TA 98 and TA 1535. Mutagens used were, nitro-o- phenylenediamine (NPD) (20μg/plate) and N-methyl- N-nitro-N-nitrosoguanidine (MNNG) (1μg/ plate). Results: The results revealed that oxycarotenoid-rich extracts isolated from Coriandrum sativum (coriander leaves) and Murraya koenigii (curry leaves) administered at doses of 1.0 mg, 2.5 mg and 5 mg per plate significantly inhibited mutagenicity induced by NPD and MNNG.Conclusion: These findings suggest that oxycarotenoid- rich extracts isolated from Coriandrum sativum (coriander leaves) and Murraya koenigii (curry leaves) have antimutagenic properties.

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Forkuo, Arnold Donkor, Kwesi Boadu Mensah, Elvis Ofori Ameyaw, Aaron Opoku Antwi, Nana Kofi Kusi-Boadum, and Charles Ansah. "Antiplasmodial and Antipyretic Activity and Safety Evaluation of the Methanolic Leaf Extract of Murraya exotica (L.)." Journal of Parasitology Research 2020 (August 5, 2020): 1–8. http://dx.doi.org/10.1155/2020/1308541.

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Background. The increasing mortality and morbidity of malaria in Africa coupled with the recent reports of antimalarial drug resistance reinforces the need for novel antimalarial agents from natural plant products with folkloric use for the disease. Murraya exotica (L.) (Rutaceae) is widely used as an ornamental plant used indigenously to treat fever, cough, and infectious wounds and eliminate pain from injury and trauma. This study was conducted to evaluate extracts of the leaves of Murraya exotica (L.) (Rutaceae) for its safety and antipyretic and antimalarial activity in rodent models. Method. In this study, the Peters 4-day suppressive and curative test in Plasmodium berghei-infected mice was used to demonstrate the antiplasmodial activity of the methanolic leaf extract of Murraya exotica (L.) (MEE). The study also evaluated the subacute toxicity study and the antipyretic activity of MEE on baker’s yeast-induced hyperthermia in rodent models. Results. Murraya exotica (L.) extract demonstrated curative antimalarial activity, with a percentage suppression of 45.84, 64.32±0.33, 56.74±2.16, and 64.61±0.67 at doses of 50, 100, 300, and 600 mg/kg, respectively. In the Peters 4-day suppressive test, MEE at dose 600 mg/kg had the highest chemosuppression (76.02±1.38%) compared with artesunate (2 mg/kg, p.o.) (82.56±0.97%). Subacute oral toxicity studies in Sprague-Dawley rats documented no deaths, with no significant changes in clinical signs, organ weights, and hematological and biochemical parameters. The LD50 of MEE was estimated to be above 1000 mg/kg in Sprague-Dawley rats. All doses of MEE and paracetamol reduced pyrexia in 1 h and 2 h after their administration. The percentage reduction of rectal temperature (TR) for the positive control (paracetamol, 150 mg/kg, p.o.) was 44.36% while the Murraya exotica extract at doses 50 mg/kg, 100 mg/kg, 300 mg/kg, and 600 mg/kg recorded 67.74%, 40.78%, 66.42%, and 59.42%, respectively. Murraya exotica at dose 100 mg/kg exhibited significant reduction (p<0.05) in baker’s yeast-induced pyrexia. Conclusions. The findings in this study show the antipyretic, curative, and suppressive antiplasmodial activity as well as the safety of the methanolic leaf extract of Murraya exotica (L.) supporting its traditional use for malaria and fever.

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Varghese, Vini Mary, Hemand Aravind, Saritha SS, and Mithilesh Jaiswal. "Screening of Antimicrobial Activity of Murraya koenigii Leaf Extracts Against Pathogenic Bacterial Strains Staphylococcus aureus and Escherichia coli Isolated from Contaminated Water." South Asian Journal of Research in Microbiology 18, no. 3 (March 5, 2024): 7–15. http://dx.doi.org/10.9734/sajrm/2024/v18i3349.

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Aim: Murraya koenigii is a widely used plant both as a potential medicinal agent and also for common cooking purposes. Aim of this present study was to determine the antimicrobial activity of Murraya koenigii leaf extracts on Staphylococcus aureus and Escherichia coli. Study Design: Screening and isolation of pathogenic bacterial strains from contaminated water. Preparation of Murraya koenigii leaf extracts using petroleum ether, acetone and ethyl acetate by using serial extraction method with Soxhlet apparatus. Place and Duration of Study: Department of microbiology, Agro biotec research centre Ltd, Poovanthuruthu, Kottayam, Kerala, India, between 2014 January to 2014 May. Methodology: Staphylococcus aureus and Escherichia coli were the bacterial strains used in this study. Morphological and biochemical analysis of microorganisms were conducted to identify the strains. Leaf extracts (petroleum ether, acetone and ethyl acetate) of Murraya koenigii were screened using MHA disc diffusion methods. Results: Various concentration of plant extracts were used to check its activity against isolated pathogens. Acetone extract of curry leaves exhibit maximum zone of inhibition against Staphylococcus aureus and petroleum ether extracts shown maximum inhibition against Escherichia coli.

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K. SHOBANA, M. Muthu kumar, B. Pon sudar jyothi, T. Sethuraja, and S. Suriya Ananthi. "A review and its potential of Murraya koenigii." World Journal of Advanced Research and Reviews 16, no. 2 (November 30, 2022): 935–41. http://dx.doi.org/10.30574/wjarr.2022.16.2.1241.

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Murraya koenigii is a multipurpose plant, the plant is a native of India. It is found in tropical and sub-tropical region in the world. All parts of plants is useful for treat and cure various diseases and useful for preparation of various pharmaceutical formulation and cosmetic preparation. Different parts of the murraya koenigii plant like roots, leaves, stem, bark, fruits and seeds have been used in combating infection and strengthening the immune system. The plants contains many major phytochemical compounds, Vitamins and Nutrients, it also rich source of nutrients and also it contains many pharmacological activity like anti-inflammatory, anti-pyretic, hypoglycemic, anti-ulcer, wound healing, anti-microbial, anti-fungal and memory enhancing etc.. The main goal of this review study was to be convey the information about Murraya koenigii plant.

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Nwaji, Azubuike Raphael. "Antihyperlipidemic property of Murraya koenigii ethanolic leaf extract on lipid profile of rats fed with cholesterol-enriched diets." Nigerian Journal of Physiological Sciences 37, no. 2 (December 31, 2022): 215–18. http://dx.doi.org/10.54548/njps.v37i2.8.

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This study was designed to investigate the effect of orally administered ethanolic leaf extract of Murraya koenigii on lipid profile of rats fed with cholesterol-enriched diets for 14 days. The study was carried out on 20 male wistar rats divided into 4 groups (n=5). All animals were given ad libitum access to drinking water. Group A was the control group and received normal rat chow, group B received cholesterol-enriched diet (CED); while group C and D received cholesterol-enriched diet and were treated with 200mg and 400mg/kg body weight of ethanolic extract of Murraya koenigii leaf respectively. Blood samples were collected by cardiac puncture on the last day of the experiment for biochemical analysis. Lipid profile was determined by Colorimetric method. Data were expressed as mean ± SEM. Differences in means were compared using ANOVA and Students T-test, P-values ≤ 0.05 were taken as statistically significant. Results showed a significant increase (p ≤ 0.05) in Total cholesterol (TC) level (117.4 ± 4.6) and low density lipoprotein cholesterol (LDL-c) level (50.1 ± 4.7) of group B rats when compared to other groups. The MK (400 mg/kg) treated rats, showed a significant reduction in TC and LDL-c levels, and a significant increase in HDL-c level when compared to CED group. However, there were no significant changes in all the lipid parameters of the treated groups when compared to the control. This study shows that cholesterol-enriched diet causes dyslipidemia and Murraya koenigii exhibited significant hypolipidemic effect on serum TC and LDL-c and increases HDL-c. Hence, Murraya koenigii exhibit antihyperlipidemic properties. Keywords: Murraya Koenigii, hyperlipidemia, Lipid profile, Cholesterol-enriched diet

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Pokala, Naveen, Vijaykumar Sayeli, and Jayasree T. "Evaluation of antipyretic activity of alcoholic extract of Murraya koenigii leaves in rabbits." International Journal of Basic & Clinical Pharmacology 8, no. 7 (June 24, 2019): 1577. http://dx.doi.org/10.18203/2319-2003.ijbcp20192653.

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Background: The present study was carried out to evaluate the antipyretic activity of alcoholic extract of Murraya koenigii leaves in rabbits by using PGE1 induced hyperpyrexia method. We found that not much work has been done on the antipyretic effect of this plant.Methods: Laboratory breed New Zealand strains of rabbits of either sex weighing 1000-1500 gm were used in the study. The animals were divided into five groups (n=6). The rabbits of all the groups were made febrile by injecting misoprostol (PGE1) subcutaneously in the dose of 100 mcg/kg. For group 1 and 2, normal saline 2ml/kg as control and aspirin 28mg/kg as standard were given respectively. Alcoholic extract of Murraya koenigii leaves in the doses of 200, 400 and 800mg/kg were administered in remaining three groups respectively. Rectal temperatures were recorded with help of digital thermometer for every 30 min after drug treatment.Results: Alcoholic extract of Murraya koenigii produced highly significant (p<0.001) antipyretic effect in 400 and 800 mg/kg doses. But onset of action was fast with 800mg/kg dose.Conclusions: This study concludes that Alcoholic extract of Murraya koenigii has fast onset of action and also exhibited sustained anti pyretic action in New Zealand rabbits.

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PAGARIYA, ASHISH SHANTILAL. "Pharmacognostical evaluation of Murraya roots." Journal of Drug Delivery and Therapeutics 9, no. 2 (March 15, 2019): 336–40. http://dx.doi.org/10.22270/jddt.v9i2.2570.

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Pharmacognostical evaluation is the first and foremost step to determine identity and assess the quality and purity of the crude drug. Murraya koenigii Spreng (Rutaceae), commonly known as Curry leaf plant or Mitha Neem in Hindi is a highly valued plant for its medicinal value and characteristic aroma. Leaves of the plants are extensively used as spice and condiment in India and other tropical countries. Present research work includes study of macroscopic, microscopic study of the root include anatomy of the thin root, anatomy of the thick root and microscopy of the powdered root. Physiochemical studies were done by using WHO recommended parameters. Photographs at different magnifications were taken with Nikon Labphot-2 microscopic unit. These findings will be useful towards establishing pharmacognostical standards and preparation of monograph of the root of Murraya koenigii.

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Chakrabarty, Manas, Amar C. Nath, Shampa Khasnobis, Manju Chakrabarty, Yaeko Konda, Yoshihiro Harigaya, and Kanki Komiyama. "Carbazole alkaloids from Murraya koenigii." Phytochemistry 46, no. 4 (October 1997): 751–55. http://dx.doi.org/10.1016/s0031-9422(97)00345-2.

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Bhattacharyya, P., A. K. Maiti, K. Basu, and B. K. Chowdhury. "Carbazole alkaloids from Murraya koenigii." Phytochemistry 35, no. 4 (March 1994): 1085–86. http://dx.doi.org/10.1016/s0031-9422(00)90680-0.

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Adebajo, Adeleke C., and Johannes Reisch. "Minor furocoumarins of Murraya koenigii." Fitoterapia 71, no. 3 (June 2000): 334–37. http://dx.doi.org/10.1016/s0367-326x(99)00163-x.

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Stefaniak, Łukasz. "Dwubiegunowa typologia społeczeństw Murraya Rothbarda." Annales Universitatis Mariae Curie-Sklodowska, sectio I – Philosophia-Sociologia 40, no. 2 (March 11, 2016): 121. http://dx.doi.org/10.17951/i.2015.40.2.121.

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<p class="Standard">Artykuł przedstawia dwubiegunowy system podziału społeczeństw zaproponowany przez amerykańskiego ekonomistę Murraya Rothbarda. Koncentrując się na opisie dwóch idealnych typów, autor stara się przybliżyć kryteria pozwalające uszeregować zbiorowości ludzkie według osi podziału wyznaczanej przez społeczeństwo kontraktowe z jednej strony i społeczeństwo hegemoniczne z drugiej. Podstawą rozważań jest Rothbardowskie pojęcie „przemocy” jako działań ludzkich mających charakter przymusowy oraz pojęcie „kontraktu”, będące fundamentem działań dobrowolnych. Tekst porusza także problematykę wolności pozytywnej i negatywnej w odniesieniu do działań państwa jako kluczowego elementu typologii zaproponowanej przez amerykańskiego badacza. Autor proponuje ponadto jego możliwe zastosowania w naukach społecznych.</p>

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Ito, Chihiro, Hideko Kanbara, Wu Tian-Shung, and Hiroshi Furukawa. "Murrayamine-C from murraya euchrestifolia." Phytochemistry 31, no. 3 (March 1992): 1083–84. http://dx.doi.org/10.1016/0031-9422(92)80087-u.

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Ito, C. "Murrayamine-C from murraya euchrestifolia." Phytochemistry 31, no. 2 (March 1992): 1083–84. http://dx.doi.org/10.1016/0031-9422(92)80233-5.

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Vinyagamoorthy, Sneha, Azhagu Madhavan Sivalingam, Arockia Alex, and Neha Brahma. "Pharmacological Effect of In Vitro Antioxidant Property and Green Synthesis of Silver Nanoparticles (AgNPs) Utilizing Murraya koenigii Antibacterial Application." Journal of Pharmacy and Bioallied Sciences 16, Suppl 2 (April 2024): S1263—S1269. http://dx.doi.org/10.4103/jpbs.jpbs_567_23.

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ABSTRACT Background: Nonessential heavy metals pose a significant threat to human health due to their toxicity. Mercury, in particular, is identified as a hazardous metal. The study aims to detect mercury using colorimetric analysis with Murraya koenigii, emphasizing the eco-friendliness of the method. Aims and Objectives: The primary objective is to detect mercury using a colorimetric analysis method employing Murraya koenigii. Additionally, the study aims to investigate the eco-friendliness of this detection method. Materials and Methods: Colorimetric analysis was conducted using Murraya koenigii to detect mercury. Ultraviolet-visible (UV-vis) spectroscopy was employed to detect the formation of silver nanoparticles (AgNPs), with a characteristic surface plasmon resonance (SPR) band observed. X-ray diffraction (XRD) data analysis was performed to determine the crystalline nature and size of AgNPs. Scanning electron microscopy (SEM) was utilized to visualize the morphology of AgNPs. Fourier transform infrared (FTIR) spectroscopy was employed to identify functional groups involved in reducing silver ions. Antibacterial properties of synthesized AgNPs were tested against various microorganisms, including Escherichia coli, Staphylococcus aureus, Streptococcus mutans, and Enterococcus faecalis. Results: Mercury was successfully detected using colorimetric analysis with Murraya koenigii. Formation of AgNPs was confirmed by UV-vis spectroscopy, with a characteristic SPR band at 418 nm. AgNPs were found to be crystalline with an average size of 5.20 nm, as determined by XRD analysis. SEM images revealed spherical and polycrystalline AgNPs. FTIR spectra indicated the involvement of the -OH group of compounds in the extract in reducing silver ions. Synthesized AgNPs exhibited antibacterial properties against various microorganisms. Conclusion: A sustainable and eco-friendly method for synthesizing AgNPs using Murraya koenigii extract was successfully developed. This method not only detected mercury but also demonstrated antibacterial properties against various microorganisms. The study underscores the health implications of nonessential heavy metals, emphasizing the importance of eco-friendly detection and mitigation methods.

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Pattar, Mohanraj, and Kerur BR. "Analysis of macro and micro nutrients content in the leaves of Murraya koenigii (l.) sprenge." International Journal of Research in Pharmaceutical Sciences 9, no. 1 (March 12, 2018): 140. http://dx.doi.org/10.26452/ijrps.v9i1.1215.

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The macro and micro nutrients content analysis was carried out for leaves of indigenous medicinal plant-Murraya Koenigii (L.) Sprenge collected from different places of North Karnataka region. The leaves of Murraya koenigii (L.) sprenge were digested with Conc. HCl, deionized water and ash (25:25:1:950) and the contents of macro, micro nutrients and harmful heavy meats such as K, Ca, Mg, Fe, Mo, Cu, Mn, Zn, Al, V, Cd and Ti were determined by an analytical atomic absorption spectrometry technique. The experimental results confirmed the presences of mineral nutrients which are beneficial to the human body and are within the limit. The heavy metal which are harmful to human body i.e., Cd, Al, within the limit but concentration of Al is absent for the leaves of Shahapur & Kappathgudda. Keywords: Murraya koenigii (L.) sprenge; Macro and Micro nutrients; Atomic absorption spectroscopy

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Hayati, Inayah. "POTENSI EKSTRAK DAUN SALAM KOJA (Murraya koenigii L. Spreng ) TERHADAP MORTALITAS Pediculus humanus capitis." Jurnal Ilmiah Pharmacy 8, no. 1 (March 1, 2021): 36–45. http://dx.doi.org/10.52161/jiphar.v8i1.341.

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KutuÂ kepala Â (Pediculus humanus capitis) Â merupakan parasit obligat yang siklus hidupnya mulai dari pradewasa sampai dewasa hidup bergantung pada inangnya. Infestasi yang lebih berat dari ektoparasit ini dapat berdampak pada timbulnya rasa gatal yang berlebihan, dapat menyebabkan luka lecet pada kulit kepala. Tujuan penelitian ini untuk mengetahui efektifitas ekstrak daun salam koja (Murraya koeniggi L.Spreng.) terhadap mortalitas Pediculus humanus capitis. Penelitian ini menggunakan metode penelitian eksperimental Â laboratorik Â dengan Â menggunakanÂ teknik Â Purposive Â Sampling. Sampel yang dibutuhkan dalam penelitian ini adalah ekstrak daun salam koja (Murraya koeniggi) dengan konsentrasi pengenceran 25%, 50%, 75% dan 100%. Berdasarkan hasil penelitian Â Ekstrak Daun Salam KojaÂ (Murraya koeniggi L.Spreng) dapat menyebabkan mortalitas kutu kepala (PediculusÂ humanusÂ capitis)Â pada konsentrasi 25 %, 50%, 75% dan 100 %. Pada konsentrasi 100% mortalitas kutu kepalaÂ yang lebih cepat dibandingkan dengan konsentrasi lainnya dengan waktu rata-rata kematian 02 menit 32 detik.

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J., Arunkumar, Vijayalakshmi M., Yesodha S., YousufAli A. S., and Parthiban R. "Antinociceptive effect of methanolic extract of Murraya koenigii leaves in swiss albino mice." International Journal of Basic & Clinical Pharmacology 9, no. 3 (February 25, 2020): 426. http://dx.doi.org/10.18203/2319-2003.ijbcp20200715.

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Background: The objective of the study was to evaluate anti-nociceptive effect of methanolic extract of Murraya koenigii leaves on thermal and mechanical pain in swiss albino mice.Methods: Thirty adult male swiss albino mice weighing 25-30 grams were selected and allocated in to five groups. Each group consists of six animals. The control group received vehicle (10 ml/kg), standard group received morphine (10 mg/kg) and test groups received dried methanolic extract of Murraya koenigii leaves (100 mg/kg, 200 mg/kg, 400 mg/kg per oral respectively) 1 hour before placing the animal over the hot plate at temperature of 55⁰C . A cut off period of 10 sec was observed to avoid damage of the paw. The response in the form of withdrawal of paws or licking of the paws. The delay in the reaction time denotes analgesic activity. The latency was recorded before and after 15, 30, 60, 120 minutes administration of drug. After washout period of 1 month the same group of animals were utilized to evaluate the analgesic effect by tail clip method for better comparison.Results: All the doses of Murraya koenigii leaves significantly delayed reaction time in hot plate method and tail clip method. The results were comparable to that produced by standard drug morphine.Conclusions: Murraya koenigii leaves has analgesic activity which was comparable to morphine.

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Roguleva, N. O., and N. V. Yankov. "Control of the viability of seeds of Murraya paniculata (L.) Jack." Vestnik of Orenburg State Pedagogical University. Electronic Scientific Journal, no. 39 (2021): 49–58. http://dx.doi.org/10.32516/2303-9922.2021.39.4.

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Yohanes, Ricky, Desi Harneti, Unang Supratman, Sofa Fajriah, and Tarso Rudiana. "Phytochemistry and Biological Activities of Murraya Species." Molecules 28, no. 15 (August 5, 2023): 5901. http://dx.doi.org/10.3390/molecules28155901.

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Murraya is a plant genus within the Rutaceae family comprising over 17 species, which are widely distributed in Asia, Australia, and the Pacific Islands. Furthermore, these species have been used in traditional medicine to treat fever, pain, and dysentery. Several reports have also extensively studied the leaves, seeds, stembark, and bark of Murraya from 1965 to 2023 to explore their natural product composition. Various phytochemical studies have revealed the isolation of 413 compounds recorded, comprising coumarins, terpenoids, flavonoids, and aromatics, as well as alkaloids, which constitute the largest proportion (46.9%). These isolated compounds have long been known to exhibit different bioactivities, such as cytotoxic and anti-inflammatory properties. Cytotoxic activity has been observed against HCT 116, HeLa, HepG2, and other cell lines. Previous studies have also reported the presence of antifungal, hepatoprotective, antihyperlipidemic, antidiarrheal, and antioxidant effects. Therefore, this review provides a comprehensive overview of Murraya species, highlighting their phytochemistry, biological activities, and potential as a source of active natural compounds.

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Sandamali, Jayasinghe A. N., Ruwani P. Hewawasam, Kamani A. P. W. Jayatilaka, and Lakmini K. B. Mudduwa. "Cardioprotective Potential of Murraya koenigii (L.) Spreng. Leaf Extract against Doxorubicin-Induced Cardiotoxicity in Rats." Evidence-Based Complementary and Alternative Medicine 2020 (March 16, 2020): 1–16. http://dx.doi.org/10.1155/2020/6023737.

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Dose-dependent cardiotoxicity of doxorubicin may lead to irreversible congestive heart failure. Although multiple mechanisms are involved, generation of free radicals is the most commonly postulated mechanism. Therefore, free radical scavengers are considered as potential therapeutic agents. As Murraya koenigii leaves are a rich source of flavonoids and phenols, they have the ability to scavenge free radicals effectively. Therefore, the objective of this study was to investigate the cardioprotective potential of Murraya leaf extract against doxorubicin-induced cardiotoxicity in rats. Rats were randomly divided into five groups with 10 animals in each group. Doxorubicin was administered intraperitonially at 18 mg/kg while lyophilized plant extract was administered orally at 2 g/kg. Dexrazoxane, at 180 mg/kg, was used as the positive control. Cardiac damage of doxorubicin control was evident with a significant increase (p<0.05) in cardiac troponin I, NT-pro BNP, AST, and LDH compared to the normal control. Plant-treated group showed cardioprotective effect by significantly reducing (p < 0.05) all of the above parameters compared to doxorubicin control (p<0.05). Increased oxidative stress in doxorubicin control was evident with a significant reduction in reduced glutathione, glutathione reductase, glutathione peroxidase, total antioxidant capacity, superoxide dismutase, and catalase activity and a significant increase in lipid peroxidation compared to the control. Interestingly, treatment with Murraya leaf extract showed a significant increase in all of the above antioxidant parameters and a significant reduction in lipid peroxidation by showing an antioxidant effect. A significant increase in myeloperoxidase activity confirmed the increased inflammatory activity in doxorubicin control group whereas plant-treated group showed a significant reduction (p<0.05) which expressed the anti-inflammatory effect of Murraya leaf extract. Doxorubicin-treated group showed histological evidence of extensive damage to the myocardium while plant-treated group showed a preserved myocardium with lesser degree of damage. Pretreatment with Murraya leaf extract may replenish cardiomyocytes with antioxidants and promote the defense against doxorubicin-induced cardiotoxicity.

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Tahia, Faiza, Md Al Amin Sikder, Mohammad Rashedul Haque, Jamil A. Shilpi, Khalijah Awang, Md Abdullah Al Mansur, and Mohammad A. Rashid. "Alkaloids, Coumarin and Cinnamic Acid Derivative from Murraya koenigii (Linn.) Spreng." Dhaka University Journal of Pharmaceutical Sciences 14, no. 1 (June 18, 2015): 29–33. http://dx.doi.org/10.3329/dujps.v14i1.23731.

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A total of seven compounds were isolated from the methanol extract of leaves of Murraya koenigii (Linn.) Spreng. The isolated compounds were characterized as arborinine (1), ferulic acid (2), umbelliferone (3), mahanimbine (4), koenimbine (5), koenidine (6) and O-demethyl murrayanine (7) by extensive spectroscopic studies, including high field NMR analysis as well as co-TLC with authentic samples, whenever possible. This is the first report of occurrence of arborinine (1) and ferulic acid (2) from Murraya species.Dhaka Univ. J. Pharm. Sci. 14(1): 29-33, 2015 (June)

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Savitha, G., and S. Balamurugan. "Pharmacognostical and Antibacterial Evaluation of Murraya koenigii (L) Spreng." International Letters of Natural Sciences 22 (August 2014): 44–50. http://dx.doi.org/10.18052/www.scipress.com/ilns.22.44.

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Our present study was aimed to detect the medicinal uses of the plant Murraya koenigii (L) Spreng belonging to the family Rutaceae by performing various studies such as Pharmacognostical, phytochemical and antibacterial activity, using seven different bacterial strains, which are harmful to human beings. The Murraya koenigii commonly known as “Curry leaf“ has been recognized in different systems of traditional medicines for the treatment of different diseases and ailments of human beings. The leaves of the plant are said to be cooling and stomachache. The study includes macroscopy, microscopy, preliminary phytochemical screening and antibacterial evaluation

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Savitha, G., and S. Balamurugan. "Pharmacognostical and Antibacterial Evaluation of <i>Murraya koenigii</i> (L) Spreng." International Letters of Natural Sciences 22 (August 5, 2014): 44–50. http://dx.doi.org/10.56431/p-9affj9.

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Our present study was aimed to detect the medicinal uses of the plant Murraya koenigii (L) Spreng belonging to the family Rutaceae by performing various studies such as Pharmacognostical, phytochemical and antibacterial activity, using seven different bacterial strains, which are harmful to human beings. The Murraya koenigii commonly known as “Curry leaf“ has been recognized in different systems of traditional medicines for the treatment of different diseases and ailments of human beings. The leaves of the plant are said to be cooling and stomachache. The study includes macroscopy, microscopy, preliminary phytochemical screening and antibacterial evaluation

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Kadam, Akshay kumar, Pradnya Shinde, Rohit Sapate, Seema Shinde, Hanmant Mali, and Nikita Gidde. "Formulation and Evaluation of Anti-Microbial Foam Hand Wash Spray of Murraya koenigii and Eugenia aromaticam Extract." Asian Journal of Research in Pharmaceutical Sciences 11, no. 3 (August 14, 2021): 195–98. http://dx.doi.org/10.52711/2231-5659.2021.00031.

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To prepare formulation of herbal hand wash from the methanolic extracts of leaves of Murraya koenigii (Curry tree) and Eugenia aromaticam (Clove) for anti acne activity. Extract was obtained from the leaves of Murraya koenigii (Curry tree) and buds of Eugenia aromaticam (Clove) by maceration method and formulation was developed by simple mixing of ingredients. Anti-microbial efficacy of the formulated herbal hand wash was performed on different microorganisms using the agar plate method. The results showed that, compared to regular hand wash, prepared herbal hand wash formulations showed a large inhibition region and extract of these plant materials can be used for formulation of hand wash and antimicrobial activity. The zone of inhibition for prepared formulation was found to be more than the standard formulation. For Staphylococcus aureus zone of inhibition was found to be 39 mm, Bacillus substillis 35 mm, and Candida albicans 42 mm which is more than the standard formulation. Extract of leaves of Murraya koenigii (Curry tree) and Eugenia aromaticam (Clove) had shown the best antimicrobial activity against Staphylococcus aureus, Bacillus substillis, and Candida albicans respectively.

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Kusumo, Galuh Gondo, M. A. Hanny Ferry Fernanda, and Heppy Asroriyah. "Identifikasi Senyawa Tanin Pada Daun Kemuning (Murraya panicullata L. Jack) Dengan Berbagai Jenis Pelarut Pengekstraksi." Journal of Pharmacy and Science 2, no. 1 (January 7, 2017): 29–32. http://dx.doi.org/10.53342/pharmasci.v2i1.63.

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ABSTRAKKemuning (Murraya paniculata L. Jack) adalah salah satu kekayaan alam yang memiliki banyak manfaat bagi kehidupan manusia. Tanin merupakan salah satu metabolit sekunder dari kemuning yang dapat digunakan sebagai anti diare dan pelangsing. Ekstrak kemuning didapatkan dari maserasi menggunakan tiga pelarut berbeda, yaitu metanol, etanol dan etil asetat. Tannin kemudian dipisahan dari ekstrak dengan menggunakan kromatografi lapis tipis (KLT) dengan berbagai jenis pelarut. Hasil nalisis menunjukkan bahwa pelarut terbaik untuk mengekstraksi tanin adalah metanol dengan perolehan 23,6989 g (31,59%). Skrining fitokimia yang dilakukan menggunakan dua reagen yang berbeda menunjukkan hasil yang positif mengandung tanin. Eluenterbaik untuk analisa tanin pada penelitian ini adalah dengan n-heksan-etil asetat (6 : 4) dengan nilai Rf sebesar 0,62.Kata Kunci : kemuning (Murraya paniculata L. Jack), tannin, kromatografi lapis tipis (KLT)ABSTRACTOrange Jessamine (Murraya paniculata L. Jack) is one of the natural treasures which has many benefits for human life. Tannin is one of secondary metabolite of orange jessamine that can be used as antidiarrhoeal and body slimming. It was obtained by maceration using 3 different solvents, such as : methanol, ethanol, and ethyl acetate. Tannins was separated from crude extract using thin layer chromatography (TLC) in different type of eluent. The analysis showed that the best solvent to extract tannin is methanol that produce of 23.6989 g (31.59%). The phytochemical screening test of the two reagents shows positif result contain tannin compound. The best eluent in this study aimed is n-hexane: ethyl acetate (6 : 4) with tannin Rf value of 0.62.Keywords: Orange jessamine (Murraya paniculata L. Jack), tannin, maceration, thin layer chromatography

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Mohan, Syam, Yahya Hasan Hobani, Emad Shaheen, Alaa Sayed Abou-Elhamd, Aymen abdelhaleem, Hassan A. Alhazmi, and Siddig Ibrahim Abdelwahab. "Girinimbine from curry leaves promotes gastro protection against ethanol induced peptic ulcers and improves healing via regulation of anti-inflammatory and antioxidant mechanisms." Food & Function 11, no. 4 (2020): 3493–505. http://dx.doi.org/10.1039/d0fo00053a.

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Furukawa, Hiroshi, and Chihiro Ito. "Three New Coumarins from Murraya exotica." HETEROCYCLES 26, no. 7 (1987): 1731. http://dx.doi.org/10.3987/r-1987-07-1731.

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Choudhary, Muhammad Iqbal, Azizuddin, Asaad Khalid, Shaikh Ziauddin Sultani, and Atta-ur-Rahman. "A New Coumarin from Murraya paniculata." Planta Medica 68, no. 1 (January 2002): 81–83. http://dx.doi.org/10.1055/s-2002-19874.

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ITO, CHIHIRO, TIAN-SHUNG WU, and HIROSHI FURUKAWA. "New carbazole alkaloids from Murraya euchrestifolia." CHEMICAL & PHARMACEUTICAL BULLETIN 36, no. 7 (1988): 2377–80. http://dx.doi.org/10.1248/cpb.36.2377.

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ITO, Chihiro, and Hiroshi FURUKAWA. "Two new coumarins from Murraya plants." CHEMICAL & PHARMACEUTICAL BULLETIN 37, no. 3 (1989): 819–20. http://dx.doi.org/10.1248/cpb.37.819.

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Kumar, Vijaya, D. B. Mahinda Wickramaratne, and Ulla Jacobsson. "Indole dimer from murraya gleniei root." Tetrahedron Letters 31, no. 36 (January 1990): 5217–18. http://dx.doi.org/10.1016/s0040-4039(00)97846-8.

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Saied, Sumayya, Shaikh Sirajuddin Nizami, and Itrat Anis. "Two new coumarins from Murraya paniculata." Journal of Asian Natural Products Research 10, no. 6 (May 12, 2008): 515–19. http://dx.doi.org/10.1080/10286020801967292.

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Reisch, Johannes, Adeleke C. Adebajo, Vijaya Kumar, and Adetunji J. Aladesanmi. "Two carbazole alkaloids from Murraya koenigii." Phytochemistry 36, no. 4 (July 1994): 1073–76. http://dx.doi.org/10.1016/s0031-9422(00)90494-1.

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Journal articles on the topic 'Murraya'

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