Relevant bibliographies by topics / Multiple roles

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Multiple roles'

Author: Grafiati
Published: 4 June 2021
Last updated: 20 February 2023

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Journal articles on the topic "Multiple roles"

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PUKALL, CAROLINE F. "Juggling Multiple Roles—and Multiples." Journal of Sexual Medicine 9, no. 8 (August 2012): 1961–62. http://dx.doi.org/10.1111/j.1743-6109.2012.02857.x.

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Wierda-Boer, Hilde H., Jan R. M. Gerris, and Ad A. Vermulst. "Managing Multiple Roles." Journal of Individual Differences 30, no. 1 (January 2009): 6–19. http://dx.doi.org/10.1027/1614-0001.30.1.6.

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Today many parents have multiple roles. This study examined how personality, domain-specific stress, and work-family interference are interrelated. Questionnaire data of 276 Dutch dual-earner couples with young children were analyzed using structural equation modeling. Findings demonstrated that job stress and parenting stress were positively related to work-to-family conflict and family-to-work conflict, respectively. For women, additionally, family-to-work conflict was strongly associated with increased levels of job stress. Finally, emotional stability functioned as an indirect predictor of work-family interference by decreasing the levels of job stress and parenting stress for both genders, but in distinctive ways. The use of couple data and inclusion of personality showed a valuable extension of existing models linking work and family.
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Fuerstenberg, Sal, and Edward Giniger. "Multiple Roles forNotchinDrosophilaMyogenesis." Developmental Biology 201, no. 1 (September 1998): 66–77. http://dx.doi.org/10.1006/dbio.1998.8944.

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KIKUZAWA, Saeko. "Aging, Multiple Roles, Distress :." Japanese Sociological Review 52, no. 1 (2001): 2–15. http://dx.doi.org/10.4057/jsr.52.2.

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Quah, Stella R. "Four sociologies, multiple roles." British Journal of Sociology 56, no. 3 (September 2005): 395–400. http://dx.doi.org/10.1111/j.1468-4446.2005.00071.x.

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MacDermid, Shelley M., Laura G. De Haan, and Gabriela Heilbrun. "Generativity in multiple roles." Journal of Adult Development 3, no. 3 (July 1996): 145–58. http://dx.doi.org/10.1007/bf02285775.

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Johnsrud, Linda K. "Korean academic women: Multiple roles, multiple challenges." Higher Education 30, no. 1 (July 1995): 17–35. http://dx.doi.org/10.1007/bf01384051.

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Allen, William Deryck. "Multiple Roles: The Diversity of Male Familial Roles." Black Scholar 37, no. 2 (June 1, 2007): 14–17. http://dx.doi.org/10.1080/00064246.2007.11413391.

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Gallagher, Padraig, and Simon Stephens. "Multiple roles, multiple perspectives: Graduates and manufacturing SMEs." Industry and Higher Education 34, no. 1 (August 19, 2019): 3–12. http://dx.doi.org/10.1177/0950422219869778.

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This article explores the workplace experience of seven science, engineering and technology graduates. The research design and methodology used in the study are exploratory, in-depth and qualitative in nature. The case study companies are located in the Republic of Ireland and Northern Ireland and employ the graduates under the FUSION project. The case study method is among a number of research techniques that has been used in a business setting to improve practice. The literature indicates that graduates need a broad range of knowledge and skills and personal attributes to operate in the workplace, including general and specific knowledge of the industry, discipline-based knowledge, technical competency, commercial awareness and management skills and key personal attributes and skills. The experience of the graduates is explored from three perspectives: the graduate, the academic and the workplace supervisor. The findings indicate that graduates undertake four key roles: technologist, project manager, team worker and graduate. Furthermore, their main responsibilities relate to knowledge of the industry, discipline knowledge, management skills and personal attributes. This article confirms the need for industry and higher education to develop and promote the workplace as a learning environment and to support graduates as they transition into the workplace.
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Wang, X., Y. Wang, L. Yu, K. Sakakura, C. Visus, J. H. Schwab, C. R. Ferrone, et al. "CSPG4 in Cancer: Multiple Roles." Current Molecular Medicine 10, no. 4 (June 1, 2010): 419–29. http://dx.doi.org/10.2174/156652410791316977.

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Dissertations / Theses on the topic "Multiple roles"

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Malone, Laurell Coleman M. S. "The Multiple Roles of Women Pursuing Doctoral Studies." Diss., Virginia Tech, 1998. http://hdl.handle.net/10919/30544.

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Increases in the employment of women in administrative and managerial careers have drawn attention to a need for research that examines the interdependency of work and family roles, a need that is particularly crucial in the area of academic administration. This was a qualitative study of the strategies and support systems women educational administrators use to deal with the multiple roles they perform in life and work while pursuing doctoral studies. Forty-four women educational administrators enrolled in Virginia Tech's fall 1996 dissertation seminar were selected to participate in a telephone interview. Each participant's responses were recorded and transcribed. Data were sorted using a variable-oriented format. Matrices were used to categorize and analyze the data, note emerging patterns of strategies and support systems, and compare and contrast roles across personal and situational variables. The women in this study cited time as the common factor in most role conflicts occurring during their years of doctoral study. Strategies that centered around time management (prioritize, delegate, compartmentalize,) were used to deal with their multiple roles. Feelings of guilt, stress, exhaustion, and isolation were common. They depended on positive and affective support systems that included family, friends, co-workers, and cohort members to deal with responsibilities of home, work, and doctoral study. A strong sense of commitment, determination, and spiritual faith was credited most often as the one thing that kept them going as they responded to the problems, issues, concerns, and challenges of performing multiple roles in life and work.
Ed. D.
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Sundström, Rasmus. "Upplevelsen av att dela hem och arbete med samma person." Thesis, Mälardalen University, Department of Social Sciences, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-402.

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Syftet med denna studie var att undersöka hur multipla roller upplevs och hanteras av personer som delar en professionell och en privat domän. Tidigare forskning har visat att multipla roller ofta upplevs som stressande och är en grund till konflikter i såväl den privata som den professionella domänen. Åtta personer i fyra intervjupar intervjuades individuellt med hjälp av en semistrukturerad intervjuguide. Studiens resultat visar att samtliga deltagare har positiva upplevelser kring de delade domänerna då de anses ge en ökad förståelse för den andra parten och leda till en utvecklad relation. Vidare forskning föreslås koncentreras kring negativa upplevelser av fenomenet då denna undersökning inte undersökt detta.

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Kotler, Pamela L. "Having it all multiple roles and mortality /." New York : Garland Pub, 1989. http://books.google.com/books?id=whFHAAAAMAAJ.

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Voronina, Vera A. "Rx plays multiple roles in eye development." Morgantown, W. Va. : [West Virginia University Libraries], 2003. http://etd.wvu.edu/templates/showETD.cfm?recnum=2984.

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Thesis (Ph. D.)--West Virginia University, 2003.
Title from document title page. Document formatted into pages; contains viii, 123 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 94-123).
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Simpson, Raina Jui Yu. "The multiple roles of zinc finger domains." Thesis, The University of Sydney, 2004. http://hdl.handle.net/2123/655.

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Zinc finger (ZnF) domains are prevalent in eukaryotes and play crucial roles in mediating protein-DNA and protein-protein interactions. This Thesis focuses on the molecular details underlying interactions mediated by two ZnF domains. The GATA-1 protein is vital for the development of erythrocytes and megakaryocytes. Pertinent to the protein function is the N-terminal ZnF. In particular, this domain mediates interaction with DNA containing GATC motifs and the coactivator protein FOG. The importance of these interactions was illustrated by the findings in Chapter 3 that naturally occurring mutations identified in patients suffering from blood disorders affect the interaction of the N-terminal ZnF with either DNA (R216Q mutation) or FOG (V205M and G208S mutations). In addition to the interaction FOG makes with GATA-1, it also interacts with the centrosomal protein TACC3. In Chapter 4, this interaction is characterised in detail. The solution structure of the region of FOG responsible for the interaction is determined using NMR spectroscopy, revealing that it is a true classical zinc finger, and characterisation of the interaction domain of TACC3 showed that the region is a dimeric coiled-coil. The FOG:TACC3 interaction appears to be mediated by a-helices from the two proteins. The data presented here represent some of the first described molecular details of how a classical ZnF can contact a protein partner. Interestingly, the a-helix used by the FOG finger to bind TACC3 is the same region utilised by DNA-binding classical zinc fingers to contact DNA. In addition to the multiple roles played by ZnFs, this domain is also known for its robustness and versatility. In Chapter 5, incomplete ZnF sequences were assessed for its ability to form functional zinc-binding domains. Remarkably, CCHX sequences (in the context of BKLF finger 3) were able to form discrete zinc-binding domains and also, mediate both protein-DNA and protein-protein interactions. This result not only illustrates the robust nature of ZnFs, it highlights the need for expanding ZnF sequence criteria when searching for functional zinc-binding modules. Together, the data presented here help further our understanding of zinc finger domains. Similar to the use of DNA-binding ZnFs in designer proteins, these data may start us on the path of designing novel protein-binding ZnFs.
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Simpson, Raina Jui Yu. "The multiple roles of zinc finger domains." University of Sydney. Molecular and Microbial Biosciences, 2004. http://hdl.handle.net/2123/655.

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Zinc finger (ZnF) domains are prevalent in eukaryotes and play crucial roles in mediating protein-DNA and protein-protein interactions. This Thesis focuses on the molecular details underlying interactions mediated by two ZnF domains. The GATA-1 protein is vital for the development of erythrocytes and megakaryocytes. Pertinent to the protein function is the N-terminal ZnF. In particular, this domain mediates interaction with DNA containing GATC motifs and the coactivator protein FOG. The importance of these interactions was illustrated by the findings in Chapter 3 that naturally occurring mutations identified in patients suffering from blood disorders affect the interaction of the N-terminal ZnF with either DNA (R216Q mutation) or FOG (V205M and G208S mutations). In addition to the interaction FOG makes with GATA-1, it also interacts with the centrosomal protein TACC3. In Chapter 4, this interaction is characterised in detail. The solution structure of the region of FOG responsible for the interaction is determined using NMR spectroscopy, revealing that it is a true classical zinc finger, and characterisation of the interaction domain of TACC3 showed that the region is a dimeric coiled-coil. The FOG:TACC3 interaction appears to be mediated by a-helices from the two proteins. The data presented here represent some of the first described molecular details of how a classical ZnF can contact a protein partner. Interestingly, the a-helix used by the FOG finger to bind TACC3 is the same region utilised by DNA-binding classical zinc fingers to contact DNA. In addition to the multiple roles played by ZnFs, this domain is also known for its robustness and versatility. In Chapter 5, incomplete ZnF sequences were assessed for its ability to form functional zinc-binding domains. Remarkably, CCHX sequences (in the context of BKLF finger 3) were able to form discrete zinc-binding domains and also, mediate both protein-DNA and protein-protein interactions. This result not only illustrates the robust nature of ZnFs, it highlights the need for expanding ZnF sequence criteria when searching for functional zinc-binding modules. Together, the data presented here help further our understanding of zinc finger domains. Similar to the use of DNA-binding ZnFs in designer proteins, these data may start us on the path of designing novel protein-binding ZnFs.
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Banga, Surinderjit. "Investigating role strain, coping and subjective well-being in combining multiple roles." Thesis, University of Plymouth, 1997. http://hdl.handle.net/10026.1/2163.

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This thesis investigates some of the salient factors involved in women's experience of combining and coping with multiple roles. A total of four studies are undertaken using both quantitative and qualitative methods to progressively focus on those factors which are identified as particularly relevant. Consequently, data is gathered using diary, interview and questionnaire methods in order to cast light upon the precise nature of the relationship between combining multiple roles, reported life satisfaction, coping and personality. In addition to identifying which particular role combinations lead to the greatest conflict, the research also clarifies the optimum number of role demands associated with reports of high life satisfaction. In so doing, the thesis provides support for the Scarcity Hypothesis as well as supplying detail about the precise nature of the role combinations associated with high and low life satisfaction. The implications of these findings for advising women on role combinations are considered. The nature of the relationship between certain key role combinations and preferred coping strategies is explored. Results suggest a relationship between certain role strains and particular coping strategies. Emotion-focused coping is preferred for inter-role conflict whereas 'superwoman' coping is more prevalent for role overload. Finally, the relationship between two major personality factors, role strain and coping, is investigated. Individuals with high scores for neuroticism are identified as expressing greater inter-role conflict, and using fewer emotion-focused coping strategies, compared with those with low scores on this scale. The implications of these findings in relation to potential social and therapeutic interventions are discussed and it is proposed that counselling and counter-conditioning might be employed to help change both cognitions and behaviour. The thesis concludes with a reflexive look at findings, issues of contention, avenues for future research, and potential practical implications.
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Xie, Xiaojun. "Multiple roles for integrins in Drosophila glial development." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/42838.

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Glia are well known for providing essential physical and metabolic support to neurons, as well as regulating neuronal development. Glial development is also modulated by external signals from other cells and the extracellular matrix (ECM). Many signals are transduced into glia by specific receptors, such as integrins for the ECM. Previous studies show that integrins are expressed by all major vertebrate glial subtypes and play key roles in many important developmental processes. However complex composition of the integrin family and difficulties of manipulating genes in vertebrates limit the understanding of in vivo functions of integrins in glia. Drosophila melanogaster is an excellent model for genetic analysis of the nervous system development. In this dissertation, I investigated integrin function in Drosophila glia. Integrins are expressed by glia in both the central and peripheral nervous systems at larval stages, where they form complexes with Talin and Integrin-Linked-Kinase (ILK). I found that integrin complexes were localized to different glia layers in the larval peripheral nerve and optic stalk. By using MARCM and RNA interference techniques, I found that integrins are required for multiple developmental events in individual and populated glia. In the peripheral nerve, integrins are important for glial ensheathment. When integrins were removed, perineurial glia failed to initiate or maintain their wrapping around the nerve and wrapping glia failed to send out numerous membrane processes between axons. In the optic stalk, integrins were necessary for glial migration, deposition and barrier formation. Removal of integrins impaired glial migration into the eye disc. Moreover, perineurial glia tended to aggregate at the anterior half and form multiple layers, and carpet glia failed to form organized septate junctions along the optic stalk. These glial defects resulted in photoreceptor axonal stalling in the eye disc and optic stalk, and mis-targeting in the brain. My work suggests that integrins are important for different aspects of Drosophila glial development and reveals a new glial function in helping photoreceptor axons through the optic stalk. Integrin distribution implicated that integrins may mediate glia-glia or glia-neuron interactions through ECM and non-ECM ligands.
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Donaldson, M. M. "Multiple roles of polo kinase in Drosophila melanogaster." Thesis, University of Cambridge, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.598595.

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The polo gene was originally identified as a maternal effect mutation in Drosophila. Flies homozygous for the original polo1 allele display a variety of defects in cell division throughout development that include a failure to correctly assemble centrosomes in syncytial embryos, spindle defects in the larval, CNS, chromosomal non-disjunction and failures in cytokines during male meiosis. These phenotypes are consistent with roles for PLKs (Polo-like kinases) in the separation and maturation of centrosomes to form a bipolar spindle and in cytokinesis, as reported in studies of the homologous enzymes in yeasts, Xenopus and mammalian cells. Here I describe the phenotypes of two new alleles of polo, polo9 and polo10 discovered in a screen of a collection of P-element insertions on the third chromosome of Drosophila. These alleles have defects in spindle architecture and centrosome reflecting the involvement of Polo in organising the centrosomes and the bipolar spindle. They also have a severe mitotic arrest at metaphase, which coincides with high levels of cyclin B and the continued presence of components of the spindle checkpoint mechanism. This is consistent with a role for Polo in regulating some aspects of anaphase-promoting complex (APC) function - a role in which Polo-like kinases have been implicated in other organisms, but not previously in Drosophila. I also present evidence for a synergistic interaction between the polo gene and the makos gene (which encodes Cdc27, a component of the APC). Mutations in makos enhance some phenotypes seen in larval brain cells in polo mutants. Finally I present the initial data from two yeast two-hybrid screens that use the N-terminal and C-terminal halves of Polo as baits to identify interacting proteins. This screen has highlighted new interacting molecules that will help elucidate the roles of Polo kinase.
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Graff, Tyler C. "Married Mothers' Multiple Roles: Implications for Cardiovascular Health." BYU ScholarsArchive, 2021. https://scholarsarchive.byu.edu/etd/8950.

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In recent years, the traditional nuclear family, as defined by social role theory with mother at home and father in the workplace, is no longer the norm. Nearly three out of every four women with children under the age of 18 are part of the workforce. Mothers are frequently juggling multiple roles as well as most of the responsibilities that are inherent in these roles. The current project examined diurnal ambulatory blood pressure influences associated with the responsibility of having a greater number of roles. We investigate differences between a self-reported healthy population of 112 married stay-at-home and 112 married employed mothers, all of whom have children under the age of 18 currently living in the home. Using a mixed multilevel model analysis, we found that the perception of equity in the division of childcare responsibilities between mothers and their husbands significantly contributed to lower systolic ambulatory blood pressure. We also found that married couples in relationships containing high positivity and low negativity had lower systolic ambulatory blood pressure than those which contained simultaneously high positivity and negativity. Additionally, there was a crossover interaction between these variables such that effect of relationship quality on both systolic and diastolic ambulatory blood pressure was moderated by the perception of equity in the division of childcare responsibilities between spouses. Lastly, we found that there were no ambulatory blood pressure differences between the employed and SAH mother conditions. These findings have applicable implications regarding dynamics and processes within marital relationships. These results demonstrate important social and relational influences on mothers' cardiovascular health.
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Books on the topic "Multiple roles"

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Barnett, Rosalind C. Multiple roles, gender and psychological distress. Wellesley, Mass: Wellesley College, 1991.

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Gilstrap, Robert L. The multiple roles of clinical faculty. Bloomington, Ind: Phi Delta Kappa Educational Foundation, 1996.

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Museum of Contemporary Photography (Columbia College (Chicago, Ill.)). Photography's multiple roles: Art, document, market, science. Chicago: Museum of Contemporary Photography, Columbia College, 1998.

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Kotler, Pamela L. Having it all: Multiple roles and mortality. New York: Garland Pub., 1989.

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Barnett, Rosalind C. Multiple roles, spillover effects and psychological distress. Wellesley, MA: Wellesley College, Center for Research on Women, 1989.

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Gerald, Corey, ed. Boundary issues in counseling: Multiple roles and responsibilities. Alexandria, VA: American Counseling Association, 1997.

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Gerald, Corey, ed. Boundary issues in counseling: Multiple roles and responsibilities. Alexandria, VA: American Counseling Association, 2014.

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1947-, Crosby Faye J., ed. Spouse, parent, worker: On gender and multiple roles. New Haven: Yale University Press, 1987.

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R, Lee John. Natural progesterone: The multiple roles of a remarkable hormone. Sebastopol, CA: BLL Pub., 1995.

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Navigating multiple identities: Race, gender, culture, nationality, and roles. Oxford: Oxford University Press, 2012.

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Book chapters on the topic "Multiple roles"

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Leftwich, Michael J. T., and Warren W. Tryon. "Managing Multiple Roles." In Your Career in Psychology, 187–99. Chichester, UK: John Wiley & Sons, Ltd, 2012. http://dx.doi.org/10.1002/9781444315929.ch14.

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Boilen, Sara. "Dual Roles, Multiple Relationships." In Ethics in Rural Psychology, 107–20. New York, NY : Routledge, 2020.: Routledge, 2020. http://dx.doi.org/10.4324/9781351007603-13.

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Simister, N. E. "Multiple roles of FcRn." In The Immunoglobulin Receptors and their Physiological and Pathological Roles in Immunity, 63–71. Dordrecht: Springer Netherlands, 1998. http://dx.doi.org/10.1007/978-94-011-5018-7_6.

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Nes, William R. "Multiple Roles for Plant Sterols." In The Metabolism, Structure, and Function of Plant Lipids, 3–9. Boston, MA: Springer New York, 1987. http://dx.doi.org/10.1007/978-1-4684-5263-1_1.

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Hu, Ziyue. "Multiple Roles and Deontic Logic." In Context, Conflict and Reasoning, 31–46. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-7134-3_3.

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Dwivedi, Devashish, and Mahak Sharma. "Multiple Roles, Multiple Adaptors: Dynein During Cell Cycle." In Advances in Experimental Medicine and Biology, 13–30. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-3065-0_2.

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Spence, Charles, and Carlos Velasco. "Packaging Colour and Its Multiple Roles." In Multisensory Packaging, 21–48. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-94977-2_2.

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Weijers, Ester M., and Victor W. M. van Hinsbergh. "Multiple Roles of Proteases in Angiogenesis." In Angiogenesis and Vascularisation, 85–99. Vienna: Springer Vienna, 2013. http://dx.doi.org/10.1007/978-3-7091-1428-5_4.

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Kelly, Michael, and Catherine Baker. "The Multiple Roles of Military Interpreters." In Interpreting the Peace, 42–61. London: Palgrave Macmillan UK, 2013. http://dx.doi.org/10.1057/9781137029843_3.

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Murakami, M. S., and G. F. Vande Woude. "The Multiple Roles of Mos during Meiosis." In Microinjection, 174–86. Basel: Birkhäuser Basel, 1999. http://dx.doi.org/10.1007/978-3-0348-8705-2_14.

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Conference papers on the topic "Multiple roles"

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Huber, Marcus J., and Tedd Hadley. "Multiple roles, multiple teams, dynamic environment." In the first international conference. New York, New York, USA: ACM Press, 1997. http://dx.doi.org/10.1145/267658.267737.

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Calaf, Gloria M., and Debasish Roy. "Abstract 1349: NSAIDs: Multiple roles in multiple environments." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-1349.

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Brown, Joseph Alexander, and Daniel Ashlock. "Using multiple worlds for multiple agent roles in games." In 2017 IEEE Conference on Computational Intelligence and Games (CIG). IEEE, 2017. http://dx.doi.org/10.1109/cig.2017.8080413.

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Wen, Jia. "Design of Multiple MDC Based on Roles." In 2009 International Conference on Information Engineering and Computer Science. IEEE, 2009. http://dx.doi.org/10.1109/iciecs.2009.5363586.

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Maniar, N. M. "Multiple Roles of A U.S. Naval Architect." In Newbuild 2000. RINA, 1995. http://dx.doi.org/10.3940/rina.newbd.2000.9.

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Miyoshi, Yoshizumi, Yoshiya Kasahara, Hirotsugu Kojima, Shoya Matsuda, Satoshi Kurita, Shinji Saito, Yuto Katoh, Ayako Matsuoka, and Iku Shinohara. "Multiple roles of plasma waves in Geospace." In 2021 International Conference on Electromagnetics in Advanced Applications (ICEAA). IEEE, 2021. http://dx.doi.org/10.1109/iceaa52647.2021.9539764.

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Qiuping, Zhang, Lv Hongjiang, and Zhou Yingtang. "Workplace multiple roles shape employee's trust centrality." In the 3rd International Conference. New York, New York, USA: ACM Press, 2019. http://dx.doi.org/10.1145/3361785.3361789.

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Grimes, Andrea, and A. J. Brush. "Life scheduling to support multiple social roles." In Proceeding of the twenty-sixth annual CHI conference. New York, New York, USA: ACM Press, 2008. http://dx.doi.org/10.1145/1357054.1357184.

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"XHITS - Multiple Roles in a Hyperlinked Structure." In International Conference on Knowledge Discovery and Information Retrieval. SciTePress - Science and and Technology Publications, 2009. http://dx.doi.org/10.5220/0002305601890195.

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Giachelli, Cecilia M. "MULTIPLE ROLES FOR OSTEOPONTIN IN REGULATING VASCULAR CALCIFICATION." In 3rd International Conference on Osteopontin and SIBLING (Small Integrin-Binding Ligand, N-linked Glycoprotein) Proteins, 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.335.

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Reports on the topic "Multiple roles"

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Price, Roz. Inclusion of Marginalised Groups in Sensitive Programming in Pakistan. Institute of Development Studies (IDS), April 2021. http://dx.doi.org/10.19088/k4d.2021.090.

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This rapid review focuses on the different variations of discrimination against marginalized groups, with a focus on the effect of intersecting and overlapping inequalities and the different experiences and outcomes they have on the varied groups. It highlights how marginalized groups have been included in interventions addressing issues of discrimination in Pakistan. The review also looks into different change interventions that deliver inclusive outcomes for women, girls and persons with disabilities with a focus on preventing violence against those groups. The review notes that intersecting inequalities have led to different experiences and outcomes relating to discrimination. It states that there is a need to address the different groups facing discrimination in a way that addresses their specified experiences because the effects of discrimination are not the same for every person. The review states that in addressing discrimination for the different groups, programmes should pursue multiple entry points to promote non-discrimination, they should work in multiple sites within and across countries and they should work with multiple partners who play different roles in communities.
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Goswami, Amlanjyoti, Sudeshna Mitra, Deepika Jha, Kaye Lushington, and Sahil Sasidharan. Land Records Modernisation in India: An Institutional, Legal & Policy Review. Indian Institute for Human Settlements, 2021. http://dx.doi.org/10.24943/9788195489305.

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This work provides an institutional, legal and policy review of crucial aspects of land records modernisation systems at the national level. Introducing property records and patterns of ownership in India, it provides an overview of various central government schemes promoting land records modernisation. It discusses the systemic and legal characteristics of land records and the proposed shift to conclusive land titling system, drawing attention to issues of tenure and property rights, especially in the urban and peri-urban context. Presenting multiple case studies on ongoing modernisation initiatives in some of the study states, the volumes also looks at the roles of multiple institutional stakeholders and the interfaces between them. Operational challenges faced in this transition to technology have also been discussed, in an attempt to bring out an overall picture of crucial issues and best practices across state-level diversities. The objective is to highlight the possibility of multiple trajectories and look at ways in which states can learn from each other by sharing experiences, while simultaneously acknowledging that there are certain issues that are typical of a particular state and must be resolved via deeper engagement with the local terrain.
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Perdigão, Rui A. P. Earth System Dynamic Intelligence with Quantum Technologies: Seeing the “Invisible”, Predicting the “Unpredictable” in a Critically Changing World. Meteoceanics, October 2021. http://dx.doi.org/10.46337/211028.

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We hereby embark on a frontier journey articulating two of our flagship programs – “Earth System Dynamic Intelligence” and “Quantum Information Technologies in the Earth Sciences” – to take the pulse of our planet and discern its manifold complexity in a critically changing world. Going beyond the traditional stochastic-dynamic, information-theoretic, artificial intelligence, mechanistic and hybrid approaches to information and complexity, the underlying fundamental science ignites disruptive developments empowering complex problem solving across frontier natural, social and technical geosciences. Taking aim at complex multiscale planetary problems, the roles of our flagships are put into evidence in different contexts, ranging from I) Interdisciplinary analytics, model design and dynamic prediction of hydro-climatic and broader geophysical criticalities and extremes across multiple spatiotemporal scales; to II) Sensing the pulse of our planet and detecting early warning signs of geophysical phenomena from Space with our Meteoceanics QITES Constellation, at the interface between our latest developments in non-linear dynamics and emerging quantum technologies.
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Chamovitz, Daniel A., and Albrecht G. Von Arnim. eIF3 Complexes and the eIF3e Subunit in Arabidopsis Development and Translation Initiation. United States Department of Agriculture, September 2009. http://dx.doi.org/10.32747/2009.7696545.bard.

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The original working hypothesis of our proposal was that The “e” subunit of eIF3 has multiple functions from both within the nucleus and in the cytoplasm. Within this model, we further hypothesized that the “e” subunit of eIF3 functions in translation as a repressor. We proposed to test these hypotheses along the following specific aims: 1) Determine the subcellular localization of the interaction between eIF3e and other eIF3 subunits, or the COP9 signalosome. 2) Elucidate the biological significance of the varied subcellular localizations of eIF3e through generating Arabidopsis eIF3e alleles with altered subcellular localization. 3.) Purify different eIF3e complexes by tandem affinity purification (TAP). 4) Study the role of eIF3e in translational repression using both in vitro and in planta assays. eIF3 is an evolutionarily ancient and essential component of the translational apparatus in both the plant and animal kingdoms. eIF3 is the largest, and in some ways the most mysterious, of the translation factors. It is a multi-subunit protein complex that has a structural/scaffolding role in translation initiation. However, despite years of study, only recently have differential roles for eIF3 in the developmental regulation of translation been experimentally grounded. Furthermore, the roles of individual eIF3 subunits are not clear, and indeed some, such as the “e” subunit may have roles independent of translation initiation. The original three goals of the proposal were technically hampered by a finding that became evident during the course of the research – Any attempt to make transgenic plants that expressed eIF3e wt or eIF3e variants resulted in seedling lethality or seed inviability. That is, it was impossible to regenerate any transgenic plants that expressed eIF3e. We did manage to generate plants that expressed an inducible form of eIF3e. This also eventually led to lethality, but was very useful in elucidating the 4th goal of the research (Yahalom et al., 2008), where we showed, for the first time in any organism, that eIF3e has a repressory role in translation. In attempt to solve the expression problems, we also tried expression from the native promoter, and as such analyzed this promoter in transgenic plants (Epel, 2008). As such, several additional avenues were pursued. 1) We investigated protein-protein interactions of eIF3e (Paz-Aviram et al., 2008). 2) The results from goal #4 led to a novel hypothesis that the interaction of eIF3e and the CSN meets at the control of protein degradation of nascent proteins. In other words, that the block in translation seen in csn and eIF3e-overexpressing plants (Yahalom et al., 2008) leads to proteasome stress. Indeed we showed that both over expression of eIF3e and the csn mutants lead to the unfolded protein response. 3) We further investigated the role of an additional eIF3 subunit, eIF3h, in transalational regulation in the apical meristem (Zhou et al., 2009). Epel, A. (2008). Characterization of eIF3e in the model plant Arabidopsis thaliana. In Plant Sciences (Tel Aviv, Tel Aviv University). Paz-Aviram, T., Yahalom, A., and Chamovitz, D.A. (2008). Arabidopsis eIF3e interacts with subunits of the ribosome, Cop9 signalosome and proteasome. Plant Signaling and Behaviour 3, 409-411. Yahalom, A., Kim, T.H., Roy, B., Singer, R., von Arnim, A.G., and Chamovitz, D.A. (2008). Arabidopsis eIF3e is regulated by the COP9 signalosome and has an impact on development and protein translation. Plant J 53, 300-311. Zhou, F., Dunlap, J.R., and von Arnim, A.G. The translation initiation factor subunit eIF3h is .1 involved in Arabidopsis shoot apical meristem maintenance and auxin response. (submitted to Development).
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Coplin, David L., Shulamit Manulis, and Isaac Barash. roles Hrp-dependent effector proteins and hrp gene regulation as determinants of virulence and host-specificity in Erwinia stewartii and E. herbicola pvs. gypsophilae and betae. United States Department of Agriculture, June 2005. http://dx.doi.org/10.32747/2005.7587216.bard.

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Gram-negative plant pathogenic bacteria employ specialized type-III secretion systems (TTSS) to deliver an arsenal of pathogenicity proteins directly into host cells. These secretion systems are encoded by hrp genes (for hypersensitive response and pathogenicity) and the effector proteins by so-called dsp or avr genes. The functions of effectors are to enable bacterial multiplication by damaging host cells and/or by blocking host defenses. We characterized essential hrp gene clusters in the Stewart's Wilt of maize pathogen, Pantoea stewartii subsp. stewartii (Pnss; formerly Erwinia stewartii) and the gall-forming bacterium, Pantoea agglomerans (formerly Erwinia herbicola) pvs. gypsophilae (Pag) and betae (Pab). We proposed that the virulence and host specificity of these pathogens is a function of a) the perception of specific host signals resulting in bacterial hrp gene expression and b) the action of specialized signal proteins (i.e. Hrp effectors) delivered into the plant cell. The specific objectives of the proposal were: 1) How is the expression of the hrp and effector genes regulated in response to host cell contact and the apoplastic environment? 2) What additional effector proteins are involved in pathogenicity? 3) Do the presently known Pantoea effector proteins enter host cells? 4) What host proteins interact with these effectors? We characterized the components of the hrp regulatory cascade (HrpXY ->7 HrpS ->7 HrpL ->7 hrp promoters), showed that they are conserved in both Pnss and Fag, and discovered that the regulation of the hrpS promoter (hrpSp) may be a key point in integrating apoplastic signals. We also analyzed the promoters recognized by HrpL and demonstrated the relationship between their composition and efficiency. Moreover, we showed that promoter strength can influence disease expression. In Pnss, we found that the HrpXY two-component signal system may sense the metabolic status of the bacterium and is required for full hrp gene expression in planta. In both species, acyl-homoserine lactone-mediated quorum sensing may also regulate epiphytic fitness and/or pathogenicity. A common Hrp effector protein, DspE/WtsE, is conserved and required for virulence of both species. When introduced into corn cells, Pnss WtsE protein caused water-soaked lesions. In other plants, it either caused cell death or acted as an Avr determinant. Using a yeast- two-hybrid system, WtsE was shown to interact with a number of maize signal transduction proteins that are likely to have roles in either programmed cell death or disease resistance. In Pag and Pab, we have characterized the effector proteins HsvG, HsvB and PthG. HsvG and HsvB are homologous proteins that determine host specificity of Pag and Pab on gypsophila and beet, respectively. Both possess a transcriptional activation domain that functions in yeast. PthG was found to act as an Avr determinant on multiple beet species, but was required for virulence on gypsophila. In addition, we demonstrated that PthG acts within the host cell. Additional effector genes have been characterized on the pathogenicity plasmid, pPATHₚₐg, in Pag. A screen for HrpL- regulated genes in Pnsspointed up 18 candidate effector proteins and four of these were required for full virulence. It is now well established that the virulence of Gram-negative plant pathogenic bacteria is governed by Hrp-dependent effector proteins. However; the mode of action of many effectors is still unresolved. This BARD supported research will significantly contribute to the understanding of how Hrp effectors operate in Pantoea spp. and how they control host specificity and affect symptom production. This may lead to novel approaches for genetically engineering plants resistant to a wide range of bacterial pathogens by inactivating the Hrp effectors with "plantabodies" or modifying their receptors, thereby blocking the induction of the susceptible response. Alternatively, innovative technologies could be used to interfere with the Hrp regulatory cascade by blocking a critical step or mimicking plant or quorum sensing signals.
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Charles J. Daniels. The Role of Multiple Transcription Factors In Archaeal Gene Expression. Office of Scientific and Technical Information (OSTI), September 2008. http://dx.doi.org/10.2172/937513.

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Beiker, Sven. Unsettled Issues Regarding Communication of Automated Vehicles with Other Road Users. SAE International, November 2020. http://dx.doi.org/10.4271/epr2020023.

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The focus of this SAE EDGE™ Research Report is to address a topic overlooked by many who choose to view automated driving systems and AVs from a “10,000-foot” perspective: how automated vehicles (AVs) will actually communicate with other road users. Conventional (human-driven) vehicles, bicyclists, and pedestrians already have a functioning system of understating each other while on the move. Adding automated vehicles to the mix requires assessing the spectrum of existing modes of communication – both implicit and explicit, biological and technological, and how they will interact with each other in the real world. The impending deployment of AVs represents a major shift in the traditional approach to ground transportation; its effects will inevitably be felt by parties directly involved with the vehicle manufacturing and use and those that play roles in the mobility ecosystem (e.g., aftermarket and maintenance industries, infrastructure and planning organizations, automotive insurance providers, marketers, telecommunication companies). Unsettled Issues Regarding Communication of Automated Vehicles with Other Road Users brings together the multiple scenarios we are likely to see in a future not too far away and how they are likely to play out in practical ways.
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Bradford, R. M. The role of multiple barriers in assuring waste package reliability; Yucca Mountain Project. Office of Scientific and Technical Information (OSTI), August 1993. http://dx.doi.org/10.2172/144902.

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Jiang, Yuwen, Chenlu Zhang, Ling Lu, Xinfeng Wang, Haiyan Liu, Yijing Jiang, Lemin Hong, Yifan Chen, Yifan Chen, and Dan Guo. Prognostic Role of Cyclin D1 in Multiple Myeloma: A Systematic Review and Meta‑analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, September 2021. http://dx.doi.org/10.37766/inplasy2021.9.0019.

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Azem, Abdussalam, George Lorimer, and Adina Breiman. Molecular and in vivo Functions of the Chloroplast Chaperonins. United States Department of Agriculture, June 2011. http://dx.doi.org/10.32747/2011.7697111.bard.

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We present here the final report for our research project entitled "The molecular and in vivo functions of the chloroplast chaperonins”. Over the past few decades, intensive investigation of the bacterial GroELS system has led to a basic understanding of how chaperonins refold denatured proteins. However, the parallel is limited in its relevance to plant chaperonins, since the plant system differs from GroEL in genetic complexity, physiological roles of the chaperonins and precise molecular structure. Due to the importance of plant chaperonins for chloroplast biogenesis and Rubisco assembly, research on this topic will have implications for many vital applicative fields such as crop hardiness and efficiency of plant growth as well as the production of alternative energy sources. In this study, we set out to investigate the structure and function of chloroplast chaperonins from A. thaliana. Most plants harbor multiple genes for chaperonin proteins, making analysis of plant chaperonin systems more complicated than the GroEL-GroES system. We decided to focus on the chaperonins from A. thaliana since the genome of this plant has been well defined and many materials are available which can help facilitate studies using this system. Our proposal put forward a number of goals including cloning, purification, and characterization of the chloroplast cpn60 subunits, antibody preparation, gene expression patterns, in vivo analysis of oligomer composition, preparation and characterization of plant deletion mutants, identification of substrate proteins and biophysical studies. In this report, we describe the progress we have made in understanding the structure and function of chloroplast chaperonins in each of these categories.
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