Dissertations / Theses on the topic 'Multidimensional assessment of health'
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Anderson, Gera. "Investigation of the multidimensional well-being assessment (MWA) in a sample of African Americans." Thesis, Pepperdine University, 2017. http://pqdtopen.proquest.com/#viewpdf?dispub=10254742.
Full textABSTRACT Existing models and measures of well-being tend to be based on an individualistic, western worldview. In addition, when cross-cultural comparisons are made, diverse cultural groups within the same national border are typically not examined. The Multidimensional Well-Being Assessment (MWA) was developed because of the absence of a culturally relevant measure to assess the well-being of those whose worldview is more consistent with collectivism. Although much attention has been given to detrimental forces in the lives of African Americans, less consideration has been given to assessing well-being in this population. In this study, a nonrandom sample was used to examine the validity of the MWA. In addition, several demographic variables were considered to explore the relationship of the dimensions of well-being contained on the MWA. A total of the 169 persons who identified as African-American or as a Black person with African ancestry participated in the study. The MWA showed strong reliability on nearly all dimensional subscales, as well as a pattern of expected significant positive and negative correlations with multiple validation measures. Significant correlations between demographic variables (i.e., age, education, income, and gender) and several dimensions on the MWA were also found. This study has implications for future research and the MWA shows promising results with regard to its psychometric properties. It is a potentially useful instrument to utilize in research that seeks to deepen understanding of life satisfaction and wellness in diverse populations, with particular attention to unique findings within the African American population.
Reinhardt, Julia. "Multidimensional assessment of heterogeneity of human CD4+CD25+ T cells in health and Type 1 Diabetes." Doctoral thesis, Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2018. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-234017.
Full textHintergrund Regulatorische T Zellen (Treg) sind eine Subpopulation der CD4+ T Zellen, welche eine wichtige Rolle in den peripheren Toleranzmechanismen des Immunsystems spielen. Ihre suppressive Funktion auf autoreaktive T Zellen kann Autoimmunität verhindern. Verschiedene Studien berichteten widersprüchlich, dass Treg in Typ 1 Diabetes (T1D) in ihrer Fähigkeit beeinträchtigt sind autoreaktive T Zellen zu supprimieren (Tan et al., 2014; Zhang et al., 2012). Treg können im Thymus differenzieren (tTreg) oder aus peripheren naïven CD4+CD25- T Zellen generiert werden (pTreg), welche ähnliche suppressive Eigenschaften wie tTreg besitzen. Es wurde außerdem berichtet, dass Treg aktiv unter tolerisierenden Konditionen induziert werden können (iTreg) (Kleijwegt et al., 2010; Yuan and Malek, 2012). Obwohl verschiedene Treg Subpopulationen beschrieben wurden, exprimieren die archetypischen humanen Treg die Hauptmarker CD4, CD25 und FOXP3 exprimieren, während CD127 herunterreguliert ist. Jedoch zeigen auch aktivierte konventionelle T Zellen (Tconv) diesen Phänotyp (Miyara et al., 2009). Da Treg und Tconv gegensätzliche Funktionen und therapeutische Indikationen aufweisen, ist es wichtig Marker zu erhalten, die sicher bona fide Treg identifizieren. Fragestellung Das Ziel meiner Arbeit ist es, die Heterogenität von humanen T Zellen zu definieren mit einen spezifischen Fokus bona fide Treg zu identifizieren. Dafür untersuchte ich die Heterogenität dieser Zellpopulation in gesunden Individuen und T1D Patienten, als Krankheitsmodell, und wie T Zellen als Treg oder Tconv definiert werden können wenn sie einem Antigen ausgesetzt sind. Material und Methoden Für das Phänotypisieren habe ich Proben von Patienten mit beginnendem T1D (Alter 7-11 Jahre), Autoantikörper positiven Patienten (Aab+) und gesunden Individuen mittels Durchflusszytometrie auf eine Reihe von Treg-assoziierten Markern getestet. Des Weiteren wurden frisch isolierte CD4+CD25+CD127lo Treg und CD+CD25- Tconv für die Transkriptomanalyse (RNAseq) genutzt, welche mit der Gesamt-RNA durchgeführt wurden. Für die funktionelle Analyse von Antigen-spezifischen Genexpressionsmustern habe ich ein Multifarbenproliferationstest entwickelt. Treg (CD4+CD25+CD127lo) und Tconv (CD4+CD25-CD127+/lo) wurden aus isolierten mononukleären Zellen des peripheren Blutes (PBMC) sortiert. Ich habe die sortierten und gefärbten Zellen mit CD4- Zellen zusammengefügt, um einen Gesamt-PBMC-Test zu simulieren und habe die Zellen mit Tetanus-, Influenza- oder Auto-antigen (GAD65, Proinsulin) stimuliert. Die Zellen wurden für 5 Tage inkubiert und die Antigen-reagierenden und -proliferierenden Zellen sowie die nicht-reagierenden Zellen Einzelzell sortiert und mittels Multiplex qPCR analysiert. Um therapeutische Ansätze zum Expandieren oder Generieren von Treg zu untersuchen, habe ich in vitro Ansätze für die de novo Induktion von Treg durch die Nutzung von tolerisierenden dendritischen Zellen (tDCs) untersucht. Die tDCs wurden von Monozyten in Anwesenheit von 1α,25-OH(2)Vitamin D3 und/oder Dexamethason differenziert und mit Lipoploysaccharid maturiert. Naïve T Zellen wurden in einem Mehrschrittverfahren mit DCs inkubiert. Die resultierenden T Zellen wurden auf DNA, Protein und funktioneller Ebene analysiert. Ergebnisse Substantielle phänotypische Heterogenität von peripheren Blut CD4+ T Zellen wurde in drei Hauptpopulationen in gesunden Individuen beobachtet und dokumentiert: ruhende Tconv (CD25-CD127+/lo), aktivierte Tconv (CD25+CD127+) und Treg (CD25+CD127lo). Weiterführend ergab der phänotypische Vergleich von Patienten mit beginnender T1D, Aab+ Patienten und gesunden Individuen keine Unterschiede in den Treg Subpopulationen. Außerdem zeigten sich keine Unterschiede in den durch RNAseq gemessenen Treg Transkriptomen von T1D Patienten und gesunden Individuen. Jedoch wurde ein kleine Gruppe von differentiell exprimierten Genen in Tconv entdeckt, welche eine mögliche Rolle von Neutrophilen in T1D andeuten. Heterogenität von Antigen-spezifischen Tconv und Treg Antworten wurde durch Genexpressionsanalysen identifiziert. Ich konnte Treg- sowie Aktivierungs-spezifische Muster definieren und verschiedene Expressionsprofile finden, wenn T Zellen durch Fremd- oder Autoantigen aktiviert wurden und ob sie die reagierenden Zellen Treg oder Tconv sind. Folgende Gene waren hauptsächlich in die Profilbildung involviert: FOXP3, CD127, mehrere Zytokine, Transkriptionsfaktoren und Aktivierungsmarker. Die Manipulation von naïven CD4+CD25- T Zellen durch tDCs führte zu einem instabilen CD25+CD127loFOXP3+ Phänotyp der generierten Zellen. Jedoch konnte keiner der weiterführenden funktionellen Analysen unterscheiden, ob die resultierenden Zellen iTreg oder aktivierte erschöpfte T Zellen waren. Insbesondere war der Methylierungsstatus der Treg-spezifisch demethylierten Region (TSDR) nicht konsistent mit einen stabilen Treg Phänotyp, was darauf hinweist, dass sogenannte tolerisiernde Protokolle nicht zu einem langlebigen Treg Phänotyp führen. Schlussfolgerungen CD4+CD25+ T Zellen sind heterogen. Ich habe Markerkombinationen definiert die helfen werden Treg von ex vivo und in vitro aktivierten Tconv Zellen zu unterscheiden. Mit diesen Mitteln war ich in der Lage zu zeigen, dass gesunde Individuen und Patienten mit Typ 1 Diabetes nicht anhand ihres Treg Phänotyps unterschieden werden können. Umfassende Einzelzell-Analysen von Antigen aktivierten T Zellen lieferten den vielversprechendsten Ansatz für die Identifizierung von Antigen-spezifischen Treg und eröffnen neue Möglichkeiten um immuntherapeutische Ansätze zu analysieren, insbesondere wenn Treg Expansion das therapeutische Ziel ist. Diese Erkenntnisse werden zukünftig für das Monitoring von Kindern, mit einem hohen T1D Risiko, genutzt die an Antigen-basierten Präventionsstudien teilnehmen
Sevo, Goran, and sevo1984@yubc net. "A multidimensional assessment of health and functional status in older Aboriginal Australians from Katherine and Lajamanu, Northern Territory." The Australian National University. Faculty of Arts, 2003. http://thesis.anu.edu.au./public/adt-ANU20051021.144853.
Full textSevo, Goran. "A multidimensional assessment of health and functional status in older Aboriginal Australians from Katherine and Lajamanu, Northern Territory /." View thesis entry in Australian Digital Theses Program, 2003. http://thesis.anu.edu.au/public/adt-ANU20051021.144853/index.html.
Full textGaray, Martinez Roberto. "Caracterización térmica dinámica de la transferencia de calor multidimensional en edificios. Dynamic performance assessment of multidimensional heat transfer in buildings." Doctoral thesis, Universitat de Lleida, 2017. http://hdl.handle.net/10803/460756.
Full textEsta tesis investiga en nuevos métodos de análisis térmico dinámico multidimensional en las envolventes arquitectónicas. Se presenta métodos de análisis térmico con aproximaciones diversas. En concreto se presentan aproximaciones variadas con métodos estacionarios o transitorios; numéricos o experimentales; y uni- o multi-dimensionales. Se presenta una formulación generalizada de la transmisión de calor en la edificación que se desarrolla en casos de estudio numéricos y experimentales. Adicionalmente, esta formulación se integra en una metodología detallada para el análisis de la transmisión de calor mediante la calibración de modelos numéricos en base a datos experimentales. Esta metodología permite su posterior uso para el análisis diferencial de medidas de mejora de la envolvente térmica de los edificios. Se presenta un caso experimental de análisis térmico diferencial de un sistema de aislamiento térmico exterior.
This thesis proposes new assessment methods related to dynamic multi-dimensional heat transfer processes in buildings. Various assessment procedures are presented with different approaches, comprising steady-state or transient; numerical or experimental; one- or multi-dimensional cases. A generalized formulation is proposed for the definition of heat transfer in buildings, which is developed into numerical and experimental case studies. This same formulation is integrated into a detailed procedure for the calibration of numerical models to meet experimental data. The use of these methods for detailed thermal assessment procedures within building envelope retrofitting processes is discussed. A case study on the differential thermal analysis of an external thermal insulation system is presented where the additional thermal resistance of the system is calculated by experimental means.
Corbett, Gina M. "The Corbett Pain Scale : a multidimensional pain scale for adult intensive care patients /." VCU Scholars Compass, 2006. http://hdl.handle.net/10156/1432.
Full textJoshi, Hrishikesh Bhaskar. "Assessment of health-related quality of life (HRQoL) in patients with ureteric stents by development and validation of a multidimensional questionnaire." Thesis, University of Bristol, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.399931.
Full textProuskas, Constantinos Panagiotis. "Investigating aspects of health among older Greeks : the development and utilisation of an Hellenic version of a multidimensional and functional assessment questionnaire." Thesis, King's College London (University of London), 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343959.
Full textMaldonado, Auccahuallpa Marie. "Validación del MD-HAQ (Multidimensional health assessment questionnaire) en un grupo de pacientes con artritis reumatoide del Hospital Nacional Dos de Mayo." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2005. https://hdl.handle.net/20.500.12672/1905.
Full textTesis de segunda especialidad
Reinhardt, Julia [Verfasser], Ezio [Akademischer Betreuer] Bonifacio, Ezio [Gutachter] Bonifacio, and Michael [Gutachter] Bachmann. "Multidimensional assessment of heterogeneity of human CD4+CD25+ T cells in health and Type 1 Diabetes / Julia Reinhardt ; Gutachter: Ezio Bonifacio, Michael Bachmann ; Betreuer: Ezio Bonifacio." Dresden : Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2018. http://d-nb.info/1156169496/34.
Full textCarl, Johannes [Verfasser], Klaus [Akademischer Betreuer] Pfeifer, and Klaus [Gutachter] Pfeifer. "Physical Activity-Related Health Competence: From the Development of a Multidimensional Assessment Instrument to Population-Specific Model Results / Johannes Carl ; Gutachter: Klaus Pfeifer ; Betreuer: Klaus Pfeifer." Erlangen : Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 2021. http://d-nb.info/1236402820/34.
Full textFerreira, Fernanda Pretti Chalet. "Adaptação transcultural da versão brasileira do interRAI-Home Care: avaliação multidimensional em assistência domiciliar." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/5/5169/tde-31082015-164115/.
Full textThe accelerated population aging process is challenging for health care strategies development at different levels of complexity. In agreement with the integrality of care in home care, the interRAI-Home Care is an example of multidimensional assessment used in different countries in case and public health management and international cooperation for better solutions to health management. The culture and functioning of home care services can influence the process of cross-cultural adaptation and use of these instruments. This study aims to perform the cross-cultural adaptation of interRAI-Home Care for the Brazilian population and verify the content and face validity of the Brazilian Portuguese version in a home care service. Cross-cultural adaptation process stages were followed with translation, back translation, assessment of equivalence by an expert committee and pretesting with the pre-final version in a sample selected by convenience of 30 subjects (n = 30) registered and attended by the Núcleo de Assistência Domiciliar Interdisciplinar do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo. The results shows that the procedures for cross-cultural adaptation were carried out with adjustments to ensure the equivalence of content of the original, translated and back translated versions after the committee experts review and consensus. Pretesting resulted in understanding of all items in the pre-final version by the interviewees and agreement between observers >= 85% for each item of the instrument thus obtaining the final version of interRAI-Home Care, translated and adapted to Brazilian Portuguese, interRAI-Assistência Domiciliar. In conclusion, the cross-cultural adaptation of a home care multidimensional assessment instrument was performed with statement of content and face validity of the instrument items and development of brazilian interRAI-Home Care version, in Brazilian Portuguese, interRAI-Assistência Domiciliar. In future steps, we suggest the evaluation of the psychometric properties of the interRAI-Assistência Domiciliar to enable its use and practical applicability in home care in Brazil
Argenta, Carla. "Modelo multidimensional de cuidado ao idoso associado aos sistemas de linguagens padronizadas de enfermagem NANDA-I, NIC E NOC." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2018. http://hdl.handle.net/10183/186134.
Full textComprehensive care for the elderly can be guaranteed through the use of the Nursing Process (PE), together with a theoretical framework such as the Multidimensional Model of Successful Aging (MMSA), which has a proposal for the evaluation of the elderly. There is, however, a gap to its use, since there are no studies that prove its effectiveness in the clinical practice of Nursing associated with the application of discipline classification systems such as NANDA-I, NIC and NOC. The objective of this study is to build an elderly care multidimensional model associated with the standardized NANDA-I, NIC and NOC Nursing language systems, applicable to the nursing consultation. The study was conducted in two different methodological steps. The first comprised a content validation study while the second a results research, which included a quasi-experimental study. The samples consisted of 15 specialists in Gerontology Nursing and 28 elderly people in a first consultation in the City of the Elderly, place of study, with age equal to or greater than 60 years, of both sexes, who presented the diagnosis of Nursing Risk of Syndrome of the Elderly (RSIF) or Fragile Elderly Syndrome (SIF), from May to October 2017. After the validation of the multidimensional model content, with the opinion of the specialists, it was applied to the elderly in four every elderly person. During the consultations the diagnoses were established, the results were measured and the Nursing interventions were implemented, according to the multidimensional model and the clinical evaluation. The specialists validated information about the anamnesis and the physical examination referring to the defining characteristics, related and risk factors of the two diagnoses and the physiological, psychological and social dimensions, as proposed by the MMSA. Validation also confirmed that of the 13 different validated Nursing outcomes, 10 were common in both diagnoses. The results validated for the two diagnoses evaluated: Equilibrium (0202), Cognition (0900), Nutritional status (1004), Self-control of chronic disease (3102), Knowledge: pain control (1843), Knowledge: control of chronic disease (1847), Knowledge: prevention of falls (1828), Knowledge: weight control (1841) and Comfort state (2008). Only two of the 13 results were validated for SIF diagnosis, being: Fatigue level (0007) and Self-care: activities of daily living (0300), and a result, Knowledge: medicine (1808), was validated only for the diagnosis RSIF. The Nursing interventions of the NIC, validated for the two Nursing diagnoses, were practically the same. Of the eight different validated interventions, only Self-care Assistance (1800) was validated exclusively for SIF diagnosis and the other seven were validated for both diagnoses. The interventions emphasize the importance of Promoting Exercise (0200), Nutrition Counseling (5246), Medication Control (2380), Cognitive Stimulation (4720), Improving Socialization (5100), Fall Prevention (6490) and Teaching the Process of the disease (5602). The second stage showed that of the 28 elderly, the majority were female (17-60.7%), with a mean age of 65.6 ± 6.3 years, and of these, 23 elderly were diagnosed with RSIF and five with SIF. Nursing results used to evaluate the elderly with RSIF and SIF showed a significant improvement in the mean of the scores of their indicators: Knowledge: control of chronic disease; Self-control of chronic disease; Knowledge: prevention of falls; Weight control; State of comfort and Participation in physical exercise program. The results Knowledge: pain control and nutritional status had significant improvement in the scores of indicators only for the elderly with RSIF, as well as the self-care evaluation: daily life activities for elderly with 9 SIF. The interventions that presented a statistically significant reduction in the use of their activities in the elderly, with both diagnoses, were Teaching: disease process and Exercise promotion, while the intervention Prevention of falls was found only in the elderly with RSIF. It is concluded that the seven nursing interventions validated by the specialists were implemented to the elderly with a diagnosis of RSIF Nursing and were considered effective, based on the evaluation of nine results that indicated a significant improvement in the comparison between the means of the first and fourth visits. Among the eight Nursing interventions implemented to the elderly with SIF Nursing diagnosis, seven were considered effective, based on the evaluation of 11 results that indicated a significant improvement in the comparison between the means of the first and fourth visits. Thus, it can be concluded that the multidimensional model of elderly care associated with standardized Nursing language systems contributes to the nurses practice in the nursing consultation, with a view to successful aging. Among the important implications and contributions of the results of this research is the possibility of supporting the link between results and validated interventions with the RSIF and SIF, facilitating nursing assessment and nursing care for the elderly in clinical practice. In addition, it is recommended to construct operational definitions for indicators of nursing outcomes. One limitation of the study was the fact that we conducted the research with specialists from the same country.
Wintermann, Gloria-Beatrice, Jenny Rosendahl, Kerstin Weidner, Bernhard Strauß, Andreas Hinz, and Katja Petrowski. "Fatigue in chronically critically ill patients following intensive care - reliability and validity of the multidimensional fatigue inventory (MFI-20)." Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2018. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-235556.
Full textRimec, Daniel. "Multidimensional Assessment For a Case Studied Zero Energy Building : Climate positive buildings with and without a connection to the district heating network." Thesis, Mälardalens högskola, Akademin för ekonomi, samhälle och teknik, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-54650.
Full textTaylor, Pennissi Locker Patrick. "Multidimensional Assessment of Pain Related Disability." Thesis, University of North Texas, 1995. https://digital.library.unt.edu/ark:/67531/metadc278421/.
Full textMair, Patrick, Ingwer Borg, and Thomas Rusch. "Goodness-of-Fit Assessment in Multidimensional Scaling and Unfolding." Taylor & Francis Group, 2016. http://epub.wu.ac.at/5354/1/mairetal2016.pdf.
Full textMorgeson, Paul Taylor. "Deconstructing Webern's Op 25, Drei Lieder: a Multidimensional Assessment." Thesis, University of North Texas, 2013. https://digital.library.unt.edu/ark:/67531/metadc283780/.
Full textRosmus, Christina. "Multidimensional pain response in Chinese infants." Thesis, McGill University, 1995. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=22799.
Full textMoshfegh, Nicole. "The multidimensional wellbeing assessment| Preliminary validation in an Iranian sample." Thesis, Pepperdine University, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=3629335.
Full textAlthough nations with a dominant worldview of individualism are a minority in the world as a whole, most psychological models are generated based on research conducted in these countries. Existing models and measures of well-being tend to have an individualistic, Western cultural bias, making it difficult to assess the well-being of those whose dominant worldview is more consistent with collectivism. Due to the absence of an existing cross-culturally relevant measure of well-being, the Multidimensional Well-Being Assessment (MWA) was developed. As attention to Middle Eastern populations has not typically received much consideration in psychological literature, this study aimed to inform researchers and clinicians of critical issues relevant to the well-being of those with ancestry and identity in Iran in addition to examining the validity of the MWA in an Iranian sample. This study used a non-random sampling method for data collection and utilized a cross-sectional correlational design to examine both the validity of the MWA and the relationship of dimensions of well-being to several demographic variables. A total of 62 participants were included in this study. The MWA showed good to excellent reliability on most MWA contexts and dimensions, in addition to showing significant positive correlations with two additional measures of well-being and significant negative correlations with a measure of distress and dysfunction. Significant correlations between several demographic variables (including age, length of time in the United States, and relationship status) and several dimensions on the MWA were also found. This study has implications for future research within the fields of culture and well-being with particular attention to unique findings within the Iranian population.
Jones, Patricia Ann Blodgett. "Assessment of dimensionality in dichotomously-scored data using multidimensional scaling." Diss., The University of Arizona, 1987. http://hdl.handle.net/10150/184267.
Full textBroughton, Ross Harold. "Distance from the protype : a multidimensional scaling approach to personality assessment." Thesis, University of British Columbia, 1986. http://hdl.handle.net/2429/26777.
Full textArts, Faculty of
Psychology, Department of
Graduate
Esparza, Oscar Armando. "Development of a multidimensional fatalism measure." To access this resource online via ProQuest Dissertations and Theses @ UTEP, 2008. http://0-proquest.umi.com.lib.utep.edu/login?COPT=REJTPTU0YmImSU5UPTAmVkVSPTI=&clientId=2515.
Full textLi, Wang-on, and 李允安. "The assessment of learning outcome: knowledgestructure." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B31227582.
Full textLeiter-McBeth, Justin Rashawn Leiter. "Heartbeat Perception and its Association with The Multidimensional Assessment of Interoceptive Awareness." Kent State University Honors College / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ksuhonors1462969942.
Full textAbdel, Malik Philip. "Multidimensional epidemiological transformations : addressing location-privacy in public health practice." Thesis, University of Plymouth, 2011. http://hdl.handle.net/10026.1/901.
Full textRechel, Maggie E. "Pregnancy Intentions and Maternal Health Behaviors Reexamined: A Multidimensional Analysis." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1243535056.
Full textRechel, Maggie Elizabeth. "Pregnancy intentions and maternal health behaviors reexamined a multidimensional analysis /." Columbus, Ohio : Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1243535056.
Full textBjertness, Espen. "A multidimensional study of dental health in urban Norwegian adults." Oslo : Dept. of Operative Dentistry, Dental Faculty, University of Oslo, 1990. http://catalog.hathitrust.org/api/volumes/oclc/22775459.html.
Full textTaylor, Lou Ella Viola. "The Multidimensional Characteristics of Persistent Pain in Adults with Sickle Cell Disease." Thesis, University of California, San Francisco, 2013. http://pqdtopen.proquest.com/#viewpdf?dispub=3587906.
Full textSickle cell disease (SCD) is a major healthcare and societal problem that affects millions of people worldwide. Sickle cell pain is the hallmark feature of SCD and includes manageable and unmanageable persistent pain that affects every aspect of an individual's life. Most of the research on pain in SCD has focused on children with acute vaso-occlusive episodes. Consequently, significant gaps exist in our knowledge of the occurrence and characteristics of manageable and unmanageable persistent pain in adults with SCD.
The specific aims of this study in a sample of adults with SCD were to: 1) determine the occurrence of persistent SCD pain and compare those with manageable and unmanageable persistent SCD pain on demographic and clinical characteristics, as well as, pain-related measures; 2) compare those with manageable and unmanageable persistent SCD pain on coping strategies; and 3) determine which factors influence quality of life (QOL) in these patients.
One hundred and three patients who were ≥18 years with SCD completed questionnaires on demographic, clinical, and pain characteristics, as well as, the Pain Catastrophizing Scale (PCS), the Duke Religious Index (DRI), and the Medical Outcomes Study Short-Form (SF-36). Patients were divided into those with manageable (average pain intensity ≤5) and unmanageable pain (average pain intensity >5) based on established cutpoints. Final analyses were done on 94 patients.
Seventy percent of patients had manageable pain and 30% had unmanageable pain. Patients with unmanageable pain reported higher ratings for all of the items on the Pain Quality Assessment Scale (PQAS); were more likely to be taking only a short-acting opioid; reported less relief from analgesic medications, and reported significantly lower SF-36 scores. Significant negative correlations were found between pain catastrophizing and religiosity/spirituality, and physical and mental health. Several variables were found to have an influence on QOL. These findings suggest that persistent pain in adults with SCD is a significant problem. More research needs to evaluate how adults with SCD cope with persistent pain and its impact on their QOL.
Snow, Tyler A. "Establishing the Viability of the Multidimensional Quality Metrics Framework." BYU ScholarsArchive, 2015. https://scholarsarchive.byu.edu/etd/5593.
Full textWilson, Stephen M., Dana K. Eriksson, Sarah M. Schneck, and Jillian M. Lucanie. "A quick aphasia battery for efficient, reliable, and multidimensional assessment of language function." PUBLIC LIBRARY SCIENCE, 2018. http://hdl.handle.net/10150/627164.
Full textDeWolfe, Nadine Alison. "Early identification of Attention Deficit Hyperactivity Disorder, a multidimensional assessment protocol for preschoolers." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape15/PQDD_0014/NQ36577.pdf.
Full textWalts, Nancy S. "Multidimensional assessment of cognitively impaired adults age 65 years of age and older." Virtual Press, 1988. http://liblink.bsu.edu/uhtbin/catkey/535895.
Full textDepartment of Educational Administration and Supervision
Mariana, Valerie Ruth. "The Multidimensional Quality Metric (MQM) Framework: A New Framework for Translation Quality Assessment." BYU ScholarsArchive, 2014. https://scholarsarchive.byu.edu/etd/4312.
Full textRamelet, Anne-Sylvie. "The development of a multidimensional pain assessment scale for critically ill preverbal children." Thesis, Curtin University, 2006. http://hdl.handle.net/20.500.11937/1524.
Full textRamelet, Anne-Sylvie. "The development of a multidimensional pain assessment scale for critically ill preverbal children." Curtin University of Technology, School of Nursing and Midwifery, 2006. http://espace.library.curtin.edu.au:80/R/?func=dbin-jump-full&object_id=17177.
Full textResults indicated significant physiological and behavioural changes in response to postoperative pain and when postoperative pain was exacerbated by painful procedures. Using the pain indicators observed in Phase One, in Phase Two the Multidimensional Assessment Pain Scale (MAPS) was developed and tested for reliability and validity in 43 postoperative preverbal children from the same settings. Internal consistency and interrater reliability were moderate and good, respectively. Concurrent and convergent validity was good. In Phase Three, the MAPS' response to analgesics and clinical utility was demonstrated in a convenience sample of 19 postoperative critically ill children aged between 0 and 3 1 months of age at a tertiary referral hospital in Western Australia. Development of a pain instrument is a complex and lengthy process. This study presents the preliminary psychometric properties that support the validity and clinical utility of the Multidimensional Assessment Pain Scale. The MAPS is a promising tool for assessing postoperative pain in critically ill young children, and its clinical validity will be strengthened with further testing and evaluation.
Shortt, Niamh Maura Kelly. "Defining regions for locality health care planning : a multidimensional geographic approach." Thesis, University of Ulster, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.232848.
Full textCastle, Courtney. "Measuring Multidimensional Science Learning: Item Design, Scoring, and Psychometric Considerations." Thesis, Boston College, 2018. http://hdl.handle.net/2345/bc-ir:107904.
Full textThe Next Generation Science Standards propose a multidimensional model of science learning, comprised of Core Disciplinary Ideas, Science and Engineering Practices, and Crosscutting Concepts (NGSS Lead States, 2013). Accordingly, there is a need for student assessment aligned with the new standards. Creating assessments that validly and reliably measure multidimensional science ability is a challenge for the measurement community (Pellegrino, et al., 2014). Multidimensional assessment tasks may need to go beyond typical item designs of standalone multiple-choice and short-answer items. Furthermore, scoring and modeling of student performance should account for the multidimensionality of the construct. This research contributes to knowledge about best practices for multidimensional science assessment by exploring three areas of interest: 1) item design, 2) scoring rubrics, and 3) measurement models. This study investigated multidimensional scaffolding and response format by comparing alternative item designs on an elementary assessment of matter. Item variations had a different number of item prompts and/or response formats. Observations about student cognition and performance were collected during cognitive interviews and a pilot test. Items were scored using a holistic rubric and a multidimensional rubric, and interrater agreement was examined. Assessment data was scaled with multidimensional scores and holistic scores, using unidimensional and multidimensional Rasch models, and model-data fit was compared. Results showed that scaffolding is associated with more thorough responses, especially among low ability students. Students tended to utilize different cognitive processes to respond to selected-response items and constructed-response items, and were more likely to respond to selected-response arguments. Interrater agreement was highest when the structure of the item aligned with the structure of the scoring rubric. Holistic scores provided similar reliability and precision as multidimensional scores, but item and person fit was poorer. Multidimensional subscales had lower reliability, less precise student estimates than the unidimensional model, and interdimensional correlations were high. However, the multidimensional rubric and model provide nuanced information about student performance and better fit to the response data. Recommendations about optimal combinations of scaffolding, rubric, and measurement models are made for teachers, policymakers, and researchers
Thesis (PhD) — Boston College, 2018
Submitted to: Boston College. Lynch School of Education
Discipline: Educational Research, Measurement and Evaluation
Guevarra, Crystle. "Fontana Community Health Assessment." Thesis, Western University of Health Sciences, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10112508.
Full textObesity often arises from poor diet and lack of exercise. Food deserts, in particular, cause people to develop poor eating habits because of the limited healthy food options and availability to cheap fast food chains. People affected by food deserts are usually found in communities of color and low-income areas. The purpose of the study was to identify whether Fontana residents are willing to adopt healthier lifestyles based on the perceptions about their own health and the health of the community. Mixed method research was utilized for the study. The participants in the study included adult residents of both sexes and all ethnic backgrounds from the City of Fontana. Those participants ranged in ages from 18 and above. The data results proved some significance between Fontana residents' will to adopt healthier lifestyles and their perceptions on personal and community health. The bivariate correlation tests indicated a statistical significance between the tested variables despite their small correlations and large unshared variances. The ANOVA tests aided with proving the validity of the proposed hypotheses. Based on the data findings, the null hypothesis was rejected and alternative hypothesis was accepted. For future research on getting residents to be more proactive about their health and that of the community, shorter and simpler surveys were advised.
Danner, Travis W. "A Formulation of Multidimensional Growth Models for the Assessment and Forecast of Technology Attributes." Diss., Georgia Institute of Technology, 2006. http://hdl.handle.net/1853/11546.
Full textKhan, Eijaz Ahmed. "Sustainable growth of informal social microenterprises (ISMs) in a developing country: a multidimensional assessment." Thesis, Curtin University, 2014. http://hdl.handle.net/20.500.11937/1650.
Full textSiquenique, Sofia. "Avaliação Multidimensional da Pessoa Idosa: análise crítica da literatura e proposta de protocolo: domínios e Instrumentos de Avaliação." Master's thesis, Instituto Politécnico de Setúbal. Escola Superior de Saúde, 2015. http://hdl.handle.net/10400.26/11119.
Full textObjetivo: definir os domínios que constituem uma avaliação multidimensional da pessoa idosa, bem como os instrumentos de avaliação mais adequados para a análise de cada um desses domínios de acordo com os critérios estabelecidos e tendo em conta a evidência científica atual. Enquadramento: tendo em conta as alterações inerentes ao envelhecimento, é esperado que a população idosa apresente necessidades complexas, havendo tendência para uma perda funcional e consequentemente da qualidade de vida visto existir uma relação estreita entre todas as vertentes biopsicossociais da pessoa. Assim, a evidência científica tem vindo a comprovar a necessidade e importância de uma avaliação multidimensional da pessoa idosa, no sentido de se compreender de uma forma global todas as necessidades dos utentes, identificando perturbações funcionais, físicas, mentais e sociofamiliares e contribuindo assim para intervenções mais adequadas e personalizadas, com consequente melhoria na resolução dos problemas identificados e prevenção de comorbilidades. Métodos: Este estudo iniciou-se com uma pesquisa na literatura científica atual com o objetivo de encontrar os domínios considerados de maior relevância numa avaliação multidimensional da pessoa idosa, bem como os instrumentos existentes para análise de cada um dos campos. Posteriormente foi realizada uma consulta de peritos através do método Delphi, onde foram incluídos 5 profissionais de saúde experts em geriatria e quatro idosos com diferentes níveis de literacia, com a finalidade de recolher as suas opiniões acerca dos domínios e instrumentos de avaliação previamente selecionados de acordo com a evidência e critérios pré-definidos. De acordo com os resultados obtidos no painel, foram então estabelecidos os domínios e instrumentos de avaliação inerentes a uma avaliação multidimensional da pessoa idosa. Resultados: numa primeira ronda quatro membros do painel responderam aos questionários, sendo que todos eles foram consensuais em relação à importância dos domínios em causa. Por sua vez, dos quatro membros que participaram nesta ronda, somente dois se manifestaram na seção relativa aos instrumentos de avaliação, estando ambos de acordo quanto à adequabilidade dos instrumentos selecionados. Contudo, ao contrário dos restantes instrumentos, no caso do domínio Dor, o consenso encontrado foi de discordância quanto à Escala Numérica da Dor enquanto ferramenta de avaliação da intensidade deste sintoma. Por sua vez, as opiniões destes membros do painel em relação à melhor alternativa a este instrumento não foram congruentes, tendo sido necessário recorrer a uma segunda ronda. Nesta fase, dois membros do painel responderam ao questionário, tendo sido possível concluir que o melhor instrumento de avaliação da intensidade da Dor é a Escala Qualitativa. Conclusão: de acordo com o painel Delphi, dos domínios e instrumentos selecionados primeiramente tendo em conta a pesquisa na literatura atual, somente a Escala Numérica da Dor não foi considerada adequada. Neste sentido, foram estabelecidos como domínios essenciais numa avaliação multidimensional da pessoa idosa, os seguintes: autoperceção de saúde; morbilidade; dor; funcionalidade; história de quedas; equilíbrio, marcha, força muscular e risco de quedas; estado cognitivo; humor/condições emocionais; aspetos sociofamiliares; estado nutricional e atividade física. Por sua vez, concluiu-se que os instrumentos mais adequados são: SF-36, MAB, Escala Qualitativa da Dor, MDG, Escala de Barthel, Índice de Lawton-Brody, Teste TUG, Escala de Equilibrio de Berg, Escala CEA, Teste “30´s chair stand”, MMSE, EDG-15, Escala de Apgar Familiar, ESSS, MNA (versão reduzida), Questionário IPAQ e Acelerómetro.
Objective: To identify the areas which are a multidimensional assessment of the elderly, as well as assessment tools best suited to the analysis of each of these areas according to established criteria, taking into account the current scientific evidence. Framework: given the inherent to aging changes, it is expected that the elderly population has higher and more complex needs with a tendency to a loss of function and hence quality of life since there is a close relationship between all biopsychosocial aspects of the person. Thus, the scientific evidence has come to prove the need and importance of a multidimensional assessment of the elderly, in order to understand in a comprehensive manner all the needs of users, identifying functional impairment, physical, mental, social and family and contributing to interventions most appropriate and customized, with consequent improvement in the resolution of identified problems and prevention of comorbidities. Methods: This study began with a survey on the current scientific literature in order to find the areas considered most relevant in a multidimensional assessment of the elderly, as well as existing tools for analyzing each of the fields. It was later held an expert consultation through the Delphi method, which included 5 professional health experts in geriatrics and four elderly people with different levels of literacy, in order to collect their opinions regarding the areas and assessment tools previously selected according with evidence and pre-defined criteria. According to the results of the panel it was then established domains and evaluation tools inherent in a multidimensional assessment of the elderly. Results: in the first round only four panel members answered the questionnaire, and all agreed on the importance of the areas concerned. In turn, between the four members who participated in this round, only two demonstrated in the section relative to the assessment instruments, agreeding both on the suitability of the selected instruments. However, unlike other instruments, in the case of pain domain, the consensus was of disagreement as to the Numerical Pain Scale as evaluation tool of the intensity of this symptom. In turn, the opinions of these panel members regarding the best alternative to this instrument were not congruent, being necessary to resort to a second round. At this stage, only two panel members responded to the questionnaire, it was possible to conclude that the best instrument to evaluate the intensity of pain is the Qualitative Scale. Conclusion: According to the Delphi panel, the areas and instruments selected primarily in view of the research in the literature, only the Numerical Pain Scale was not considered appropriate. It was established as key areas in a multidimensional assessment of the elderly: health auto-perception; morbidity; pain; functionality; history of falls; balance, gait, muscle strength and risk of falls; cognitive state; mood / emotional conditions; social-familial aspects; nutritional status and physical activity. In turn, it was concluded that the most appropriate instruments are: SF-36, MAB, Verbal Pain Scale, MDG, Barthel Index, Lawton-Brody Index, TUG Test, Berg Balance Scale, CEA Scale, "30's chair stand" test, MMSE, GDS-15, Family Apgar Score, ESSS, MNA (reduced version), IPAQ and Accelerometer.
Grefe, Linderbaum Beth. "FEEDBACK ORIENTATION: THE DEVELOPMENT AND VALIDATION OF A MULTIDIMENSIONAL MEASURE." University of Akron / OhioLINK, 2006. http://rave.ohiolink.edu/etdc/view?acc_num=akron1152204402.
Full textBroaddus, Michelle. "Multidimensional implicit and explicit condom attitudes: Structure and implications for health messages." Connect to online resource, 2008. http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:dissertation&res_dat=xri:pqdiss&rft_dat=xri:pqdiss:3315812.
Full textDangel, Trever. "Associations between Multidimensional Spirituality and Mental Health: Positive Psychological Traits as Mediators." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/etd/3436.
Full textZetterberg, Lena. "Multidimensional Aspects of Dystonia : Description and Physiotherapy Management." Doctoral thesis, Uppsala universitet, Institutionen för neurovetenskap, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9417.
Full textDeville, Craig W. "An Investigation of Content- and Construct-Related Evidence of Self-Assessment Items Using Multidimensional Scaling." The Ohio State University, 1994. http://rave.ohiolink.edu/etdc/view?acc_num=osu1389191999.
Full textDeville, Craig W. "An investigation of content- and construct-related evidence of self-assessment items using multidimensional scaling /." The Ohio State University, 1993. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487848891513513.
Full textLett, Robin M. "A multidimensional investigation of the relationships among spiritual maturity, spiritual experience, and health-promoting behaviors." Virtual Press, 2002. http://liblink.bsu.edu/uhtbin/catkey/1233202.
Full textDepartment of Counseling Psychology and Guidance Services