Academic literature on the topic 'Multi-component Phase Separation'
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Journal articles on the topic "Multi-component Phase Separation"
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Lo Celso, F., A. Triolo, and R. Triolo. "Phase separation in multi-component mixtures: the four-component case." Physica A: Statistical Mechanics and its Applications 304, no. 1-2 (February 2002): 299–307. http://dx.doi.org/10.1016/s0378-4371(01)00511-8.
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Bremer, Anne, Ammon E. Posey, Madeleine B. Borgia, Wade M. Borcherds, Mina Farag, Rohit V. Pappu, and Tanja Mittag. "Quantifying Coexistence Concentrations in Multi-Component Phase-Separating Systems Using Analytical HPLC." Biomolecules 12, no. 10 (October 14, 2022): 1480. http://dx.doi.org/10.3390/biom12101480.
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Over the last decade, evidence has accumulated to suggest that numerous instances of cellular compartmentalization can be explained by the phenomenon of phase separation. This is a process by which a macromolecular solution separates spontaneously into dense and dilute coexisting phases. Semi-quantitative, in vitro approaches for measuring phase boundaries have proven very useful in determining some key features of biomolecular condensates, but these methods often lack the precision necessary for generating quantitative models. Therefore, there is a clear need for techniques that allow quantitation of coexisting dilute and dense phase concentrations of phase-separating biomolecules, especially in systems with more than one type of macromolecule. Here, we report the design and deployment of analytical High-Performance Liquid Chromatography (HPLC) for in vitro separation and quantification of distinct biomolecules that allows us to measure dilute and dense phase concentrations needed to reconstruct coexistence curves in multicomponent mixtures. This approach is label-free, detects lower amounts of material than is accessible with classic UV-spectrophotometers, is applicable to a broad range of macromolecules of interest, is a semi-high-throughput technique, and if needed, the macromolecules can be recovered for further use. The approach promises to provide quantitative insights into the balance of homotypic and heterotypic interactions in multicomponent phase-separating systems.
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Usui, Satoshi, and Hiroshi Koibuchi. "Finsler Geometry Modeling of Phase Separation in Multi-Component Membranes." Polymers 8, no. 8 (August 4, 2016): 284. http://dx.doi.org/10.3390/polym8080284.
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Sreedhar, Balamurali, and Andreas Seidel-Morgenstern. "Preparative separation of multi-component mixtures using stationary phase gradients." Journal of Chromatography A 1215, no. 1-2 (December 2008): 133–44. http://dx.doi.org/10.1016/j.chroma.2008.11.003.
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Reyes, Catherine G., Jörg Baller, Takeaki Araki, and Jan P. F. Lagerwall. "Isotropic–isotropic phase separation and spinodal decomposition in liquid crystal–solvent mixtures." Soft Matter 15, no. 30 (2019): 6044–54. http://dx.doi.org/10.1039/c9sm00921c.
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Kim, Junseok. "Phase-Field Models for Multi-Component Fluid Flows." Communications in Computational Physics 12, no. 3 (September 2012): 613–61. http://dx.doi.org/10.4208/cicp.301110.040811a.
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AbstractIn this paper, we review the recent development of phase-field models and their numerical methods for multi-component fluid flows with interfacial phenomena. The models consist of a Navier-Stokes system coupled with a multi-component Cahn-Hilliard system through a phase-field dependent surface tension force, variable density and viscosity, and the advection term. The classical infinitely thin boundary of separation between two immiscible fluids is replaced by a transition region of a small but finite width, across which the composition of the mixture changes continuously. A constant level set of the phase-field is used to capture the interface between two immiscible fluids. Phase-field methods are capable of computing topological changes such as splitting and merging, and thus have been applied successfully to multi-component fluid flows involving large interface deformations. Practical applications are provided to illustrate the usefulness of using a phase-field method. Computational results of various experiments show the accuracy and effectiveness of phase-field models.
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Bao, LingLing, ZhongLiang Liu, HengWei Liu, WenMing Jiang, Ming Zhang, and Jian Zhang. "Phase equilibrium calculation of multi-component gas separation of supersonic separator." Science China Technological Sciences 53, no. 2 (February 2010): 435–43. http://dx.doi.org/10.1007/s11431-009-0326-7.
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Kuo, Yuen-Cheng, and Shih-Feng Shieh. "Phase separation of multi-component Bose–Einstein condensates in optical lattices." Journal of Mathematical Analysis and Applications 347, no. 2 (November 2008): 521–33. http://dx.doi.org/10.1016/j.jmaa.2008.06.044.
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Ferreiro-Córdova, Claudia, Emanuela Del Gado, Giuseppe Foffi, and Mehdi Bouzid. "Multi-component colloidal gels: interplay between structure and mechanical properties." Soft Matter 16, no. 18 (2020): 4414–21. http://dx.doi.org/10.1039/c9sm02410g.
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Suzuki, Masanori, and Toshihiro Tanaka. "Thermodynamic Prediction of Spinodal Decomposition in Multi-component Silicate Glass for Design of Functional Porous Glass Materials." High Temperature Materials and Processes 31, no. 4-5 (October 30, 2012): 323–28. http://dx.doi.org/10.1515/htmp-2012-0086.
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AbstractThe authors have investigated metastable phase separation in multi-component silicate glass for the fabrication of porous glass from multi-component slag. Spinodal decomposition forms an interconnected microstructure in glass spontaneously, and porous glass is obtained by leaching one of the decomposed phases with an acid solution. This porous glass can be used for a filter to remove impurities in polluted water or air. In this study, the metastable miscibility gap was predicted in multi-component silicate glass using thermodynamic analyses where glass was regarded as a super-cooled liquid phase. Occurrence of spinodal decomposition was observed in annealed glass, and it corresponded to the predicted miscibility gap. Then, we fabricated porous glass using spinodal decomposition in multi-component borosilicate glass and by removing one of the decomposed phases. Furthermore, for the creation of functional porous glass applicable for environmental purification, the spinodal decomposition was prepared in multi-component borosilicate glass containing titanium oxide based on the predicted metastable miscibility gap in multi-component silicate glass.
Dissertations / Theses on the topic "Multi-component Phase Separation"
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Chen, Wei. "Theoretical study of multi-component fluids confined in porous media." Thesis, Lyon, École normale supérieure, 2011. http://www.theses.fr/2011ENSL0624.
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Un milieu poreux ou un matériau poreux comprend deux régions interconnectées : une perméable par un gaz ou un liquide et l’autre imperméable. Beaucoup de substances naturelles comme les roches, le sol et les tissus biologiques (par exemple, os, bio-membranes) sont poreuses ainsi que les matériaux manufacturés comme les ciments et les céramiques, etc. Les matériaux poreux ont des applications technologiques importantes et nombreuses, par exemple, comme tamis moléculaires, catalyseurs ou senseurs chimiques. Il existe un nombre très important d’études en expérience et en théorie pour comprendre la structure des matériaux poreux ainsi que les propriétés des substances confinées dans ces matériaux. Dans leur travail de pionnier, Madden et Glandt ont proposé un modèle très simple pour l’adsorption de fluide dans des milieux poreux désordonnés. Dans ce modèle, on forme la matrice en prenant une configuration figée instantanément d’un système à l’équilibre (“quench” en anglais) et puis un fluide est introduit dans une telle matrice. Récemment, T. Patsahan, M. Holovko et W. Dong ont généralisé la “scaled particle theory” (SPT) aux fluides confinés et obtenu ainsi des équations d’état analytiques pour un fluide de sphère dure dans plusieurs modèles de matrice. Dans un premier temps, j’ai développé la version de la SPT pour un mélange de sphères dures additives confiné en milieu poreux. Les expressions pour les valeurs au contact de différentes fonctions de distribution ont été obtenues également. J’ai effectué aussi des simulations de Monte Carlo. Les résultats de ces simulations sont utilisés pour valider les résultats théoriques. Ensuite, j’ai étudié aussi la séparation de phase d’un mélange binaire des sphères dures non additives confiné dans un milieu poreux. Pour obtenir l’équation d’état, nous avons utilisé une théorie de perturbation en prenant un fluide de sphères dures additive comme système de référence. Les résultats donnés par cette théorie sont en bon accord avec les résultats de simulation Monte CarloA porous medium or a porous material (called as frame or matrix also) usually consists of two interconnected rejoins: one permeable by a gas or a liquid, i.e., pore or void, and the other impermeable. Many natural substances such as rocks, soils, biological tissues (e.g., bio membranes, bones), and manmade materials such as cements, foams and ceramics are porous materials. Porous materials have important technological applications such as molecular sieve, catalyst, chemical sensor, etc. In recent years, there have been considerable investigations for understanding thoroughly the structure of these materials as well as the behavior of substances confined in them. Much effort (both experimental and theoretical) has been devoted to the study of porous materials. In their pioneering work, a very simple model for the fluid adsorption in random porous media was proposed by Madden and Glandt. The matrix in Madden-Glandt model is made by quenching an equilibrium system. Then, a fluid is adsorbed in such a matrix. Recently, T. Patsahan, M. Holovko and W. Dong have extended the scaled particle theory (SPT) to confined fluids and derived analytical equations of state (EOS) for a hard sphere (HS) fluid in some matrix models. In this thesis, using SPT method, I obtained the equation of state of additive hard-sphere (AHS) fluid mixtures confined in porous media. The contact values of the fluid-fluid and fluid-matrix radial distribution functions (RDF) were derived as well. The results of the contact values of the RDFs and the chemical potentials of different species were assessed against Monte Carlo simulations. Moreover, I analyzed also the fluid-fluid phase separation of non-additive hard sphere (NAHS) fluid confined in porous media. An equation of state is derived by using a perturbation theory with a multi-component fluid reference. The results of this theory are in good agreement with those obtained from semi grand canonical ensemble Monte Carlo simulations
Conference papers on the topic "Multi-component Phase Separation"
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SALASNICH, L., L. REATTO, and A. PAROLA. "SHELL EFFECTS AND PHASE SEPARATION IN A TRAPPED MULTI-COMPONENT FERMI SYSTEM." In Proceedings of the 8th Conference on Problems in Theoretical Nuclear Physics. WORLD SCIENTIFIC, 2001. http://dx.doi.org/10.1142/9789812811356_0016.
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Hentges, Nicholas, A. S. M. Sazzad Parveg, and Albert Ratner. "Experimental Investigation of Multi-Component Emulsion Fuel Stability." In ASME 2021 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/imece2021-70105.
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Abstract The emulsification of water with liquid fuels to modify combustion characteristics has been of great interest to the combustion research community for some time. The emulsions are usually comprised of only water combined via ultrasonification (or other mechanical methods) with a base hydrocarbon fuel. These emulsions show improved combustion characteristics, such as lower combustion temperatures, and lower emissions. One of the main issues with these emulsions, however, is that these emulsions are not stable and are prone to phase separation over time, which inhibit the economic viability and practical application of these fuels. There are a multitude of ways being researched to improve fluid stability, including new mixing techniques, the addition of nanoparticles, as well as the addition of other fluids. The addition of ethanol to water-based emulsions has been shown to decrease the size of water droplets in the emulsion, allowing for a more homogenous mixture. With the aviation industry being a sizeable source of the global emissions caused by transportation, methods of lowering the emissions of aviation fuels as well as greener alternatives are needed. Present research quantitatively studies how the addition of ethanol to water and jet fuel emulsions affects the stability of the emulsion. A non-invasive, quantitative, and economical method for determining phase separation is used to study the stability of these multi-component mixtures. The system periodically measures the phase separation of the fluid column by automatically shining light through the fluid and detecting how much interference is created by the fluid. The system does this at five different depths of the fluid so the phase separation of the emulsion can be tracked in more detail. Ethanol and water are studied at mixtures of 5%, 10%, 15%, and 20% ethanol by weight and 5% and 10% water by weight emulsified with jet fuel. It is expected that the present research will lay additional foundation for the future study of fuel emulsion stability, as well as spark additional interest in utilizing emulsions to improve fuels.
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Traxinger, Christoph, Hagen Müller, Michael Pfitzner, Steffen Baab, Grazia Lamanna, Bernhard Weigand, Jan Matheis, Christian Stemmer, Nikolaus A. Adams, and Stefan Hickel. "Experimental and Numerical Investigation of Phase Separation due to Multi-Component Mixing at High-Pressure Conditions." In ILASS2017 - 28th European Conference on Liquid Atomization and Spray Systems. Valencia: Universitat Politècnica València, 2017. http://dx.doi.org/10.4995/ilass2017.2017.4756.
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Experiments and numerical simulations were carried out in order to contribute to a better understanding and predic-tion of high-pressure injection into a gaseous environment. Specifically, the focus was put on the phase separation processes of an initially supercritical fluid due to the interaction with its surrounding. N-hexane was injected into a chamber filled with pure nitrogen at 5 MPa and 293 K and three different test cases were selected such that they cover regimes in which the thermodynamic non-idealities, in particular the effects that stem from the potential phase separation, are significant. Simultaneous shadowgraphy and elastic light scattering experiments were conducted to capture both the flow structure as well as the phase separation. In addition, large-eddy simulations with a vapor- liquid equilibrium model were performed. Both experimental and numerical results show phase formation for the cases, where the a-priori calculation predicts two-phase flow. Moreover, qualitative characteristics of the formation process agree well between experiments and numerical simulations and the transition behaviour from a dense-gasto a spray-like jet was captured by both.DOI: http://dx.doi.org/10.4995/ILASS2017.2017.4756
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Kolev, Nikolay Ivanov. "SKYTHIA: A Universal Multi-Phase Flow Analyzer." In 2014 22nd International Conference on Nuclear Engineering. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/icone22-31285.
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SKYTHIA is a computer code for computational simulation of transient multi-phase flows based on three multi-component velocity fields in a porous structure that may change its geometry in time. The foundation of the computer code SKYTHIA allows applications for mathematical simulation of a variety of processes. From • two-phase gas-plasma multi-component hydrogen detonation in pipe-network with dissociation of the gases, • through condensation water-steam shock waves in complex pipe networks, • gas solution and dissolution in liquids, dissolved gas release from water in pipe network and gas-slug formation and transport, • pressure wave propagation, piping force computation and risk analysis in conventional island of 1700 MWe power plant including detailed models of the high pressure turbine, • diesel injection problems, • particles sedimentation in water, • turbulent mixing and transport in a nuclear power plant sump, • termite injection by high pressure steam-hydrogen mixture into air environment, melt-water interaction in postulated SWR 1000 severe accidents, alumina melt jet dropped into a subcooled water, Urania melt jet dropped in water, • void formation in existing-, • or future boiling water reactors, • void fraction and velocity distribution in nuclear reactors with different thermal powers, • modern steam generator simulation, thermal coupling of multi-phase non-equilibrium three fluid non-homogeneous non-equilibrium flow inside the primary piping systems to complete 3D multi-phase non-equilibrium three fluid non-homogeneous non-equilibrium flow inside secondary systems with cyclones and dryers, • volume fraction of steam in family of steam generators with different power, • water velocities and void fraction in flooding reservoir for primary emergency condenser being operating on the secondary site as boiler; thermal coupling of multi-phase non-equilibrium three fluid non-homogeneous flow inside the primary piping systems to complete 3D multi-phase non-equilibrium three fluid non-homogeneous flow inside secondary systems, • complete system for moisture separation of typical PWR, dynamic performance: multi-phase non-equilibrium three fluid non-homogeneous flow inside the secondary moisture separation system, • local volume fractions of oxide and sodium liquid as a function of (r, z) in the vertical plane for a fast breeder reactor during melt water interaction; energetic interaction of molten reactor material with liquid sodium in argon environment, • modern pre-heater (condenser) simulation, thermal coupling of single phase flow inside the primary piping systems to complete 3D multi-phase non-equilibrium three fluid non-homogeneous non-equilibrium condensing flow inside secondary systems, etc. All this applications demonstrate the capability of single model architecture to handle different material systems, different intensities of interactions, and large variety of the spatial and temporal scales of the simulated processes. This paper gives brief information about the basic principles used to build SKYTHIA, part of the validation procedure and illustrations of some very complex process simulations.
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Deng, Feng, Shiwen Chen, Guanhong Chen, and Mengying Wang. "Intelligent Decision Making and Optimization of Artificial Lifting Based on MR Multi-Phase Flow Detection." In Offshore Technology Conference Asia. OTC, 2022. http://dx.doi.org/10.4043/31349-ms.
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Abstract Quantitative information regarding multi-phase flow of oil, gas and water in wells or pipelines are very important in guiding the artificial lifting parameters optimization and tool selection. At present, there is no reliable technology available which can accurately measure split flow of multi-phase fluids without separating oil, gas and water. So far, the multi-phase flow measurement technique commonly adopted globally is to carry out by phase separation after produced fluid entering the gathering station through the pipelines, where the content of each component is measured separately. The indirect measurement methods are usually with low-efficiency, high-cost and delay-delivery, and hard to reflect the real instantaneous fluid producing properties at wellheads or pipelines. Therefore, it is urgent to seek for accurate and reliable multi-phase flow detection devices and methods that can meet the monitoring demands for oil and gas resources. This paper proposed a nuclear magnetic resonance (NMR) device and analytical methods for detecting multi-phase fluid. At the same time, it puts forward the intelligent decision-making and optimization technology based on measurement, cloud computing and automatic control. As a green, efficient and accurate method for oil and gas detection, the NMR can realize online measurement for each component of multi-phase flow. Then based on the internet and large data analysis technology to achieve artificial lifting parameters optimization, while based on automatic control technology to achieve artificial lifting equipment negative feedback control. This progress helps to apply the NMR technique in petroleum industry to achieve green, efficient, real-time and low-cost multi-phase flow measurement. Combined with large data, Internet of Things (IOT) and automatic control technology to achieve intelligent artificial lifting technology and system.
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Moon, Jei-Kwon, Eil-Hee Lee, Chong-Hun Jung, and Byung-Chul Lee. "Separation of Technetium in Nitric Acid Solution With an Extractant Impregnated Resin." In 14th International Conference on Nuclear Engineering. ASMEDC, 2006. http://dx.doi.org/10.1115/icone14-89797.
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An extractant impregnated resin (EIR) was prepared by impregnation of Aliquat 336 into Amberlite XAD-4 for separation of technetium from rhodium in nitric acid solution. The prepared EIR showed high preference for rhenium (chemical analogue of technetium) over rhodium. The adsorption isotherms for rhenium were described well by Langmuir equation in both the single and multi-component systems. Maximum adsorption capacities obtained by modelling the isotherms of rhenium were 2.01 meq g−1 and 1.97 meq g−1 for the single and the multi-component systems, respectively. Column tests were also performed to confirm the separation efficiency of rhenium using a jacketed glass column (φ11 × L 150). The EIR column showed successful separation of rhenium with the breakthrough volume of about 122 BV for the breakthrough concentration of 0.08. Also the breakthrough data were modelled successfully by assuming a homogeneous diffusion model in the particle phase. The diffusivities obtained from the modelling were in the order of 10−7 cm2 min−1 for a rhenium. The rhenium adsorbed on the bed could be eluted with a high purity by using a nitric acid solution.
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Wang, Xianjun, Xiangbin Liu, Borui Li, Qiang Yin, Zhonglian Han, Jinyu Li, Kejun Liu, et al. "The Application of the Multi-Component Thermal Fluid Huff and Puff Technology to Daqing Heavy Oil Block." In International Petroleum Technology Conference. IPTC, 2021. http://dx.doi.org/10.2523/iptc-21415-ms.
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Abstract The reservoir of Daqing Heidimiao Oilfield (permeability 1736×10−3μm2) contains heavy oil, with the average viscosity of 3306 mPa•s. It is developed by steam flooding and steam huff and puff, however, the recovery rate is only 14.6%. Therefore, the multi-component thermal fluid huff-and-puff technology is applied to, dealing with pertinent problems such as gas channeling, corrosion and oil pump lock in the process so as to improve oil recovery and production. Mechanism: Cooling by water, the ultra-high temperature gas generated via combustion of diesel or natural gas with air produces a multi-component thermal fluid containing CO2,N2 and vapor, combining the advantages of gas absorption and thermal recovery. Simulation: A multi-component and multi-phase percolation model is built to optimize the huff-and-puff parameters including composition ratio, temperature and injection volume. Supporting techniques: a high temperature oil-and-acid resistant foam system to form a precedent-blocking slug and automatically adjust the huff-and-puff profile. a dedicated low-cost and high-efficiency corrosion inhibitor system to realize corrosion-resistance. a four-node down-hole gas-liquid separation device to increase efficiency. The comprehensive reduced-viscosity rate is more than 30%; high-pressure air chambers, ranging from 0.2 to 2.0MPa, are formed for elastic energy replenishment. Field tests show the average annual oil increase per well is about 3800 barrels, with the highest being about 7200 barrels. The numerical simulation results show that the optimal composition ratio (N2: CO2: vapor) is 5:1:1.5, that the best injection amount is 30∼50×104Nm3 and that the injection temperature is preferably 280 ∼ 300 °C. The oil-and-acid resistant foaming agent has improved recovery efficiency, as a significantly improved profile of gas absorption, and the oil extraction degree increases by about 31.5%. High temperature corrosion is prevented, through intermittent injection of high-temperature-resistant corrosion inhibitor (corrosion inhibition rate 70.5% at 350 °C), and the frequency of pipeline corrosion is reduced averagely by 98.5%. Air-lock in pump vanishes via gas-liquid separation devise, with the average indoor pump efficiency increases by more than 50% (gas-liquid ratio ≤3000m3/m3)and the one in field test increases from less than 20% to over 45%. More importantly, the maintenance period has reached 662d. This technology has been applied to 98 wells in Daqing to date, 95 of which are stimulated successfully. The multi-component thermal fluid huff-and-puff technology solves the problems such as gas channeling, corrosion and air-lock in pumps through supporting techniques and the synergism of steam flooding and thermal recovery to enhance oil recovery and can be used as a superseded technology after steam huff-and-puff treatment to increase the EUR, especially for heavy oil reservoirs with medium and high permeability.
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Soleimanikutanaei, Soheil, Esmaiil Ghasemisahebi, Cheng-Xian Lin, and Dexin Wang. "Modelling of Shell and Tube Transport Membrane Condenser Heat Exchangers in Low Grade Waste Heat and Water Recovery Applications." In ASME 2016 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/imece2016-67906.
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In this study Transport Membrane Condenser (TMC), a new waste heat and water recovery technology based on a nanoporous ceramic membrane vapor separation mechanism has been studied for waste heat and water recovery in power plant application. TMC is able to extract condensate pure water from the flue gas in the presence of other non-condensable gases (i.e. CO2, O2 and N2). The effects of mass flow rate of flue gas and water vapor content of flow on the heat transfer and condensation rate of a TMC shell and tube heat exchanger have been studied numerically. A single phase multi-component model is used to assess the capability of single stage TMC heat exchangers in terms of waste heat and water recovery at various inlet conditions. Numerical simulation has been performed using ANSYS-FLUENT software and the condensation rate model has been implemented applying User Define Function.
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Ghasemisahebi, Esmaiil, Soheil Soleimanikutanaei, Cheng-Xian Lin, and Dexin Wang. "Numerical Study of Transport Membrane Condenser Heat Exchangers." In ASME 2016 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/imece2016-67882.
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In this study tube bundle Transport Membrane Condenser (TMC) has been studied numerically. The tube walls of TMC based heat exchangers are made of a nano-porous material and has a high membrane selectivity which is able to extract condensate pure water from the flue gas in the presence of other non-condensable gases (i.e. CO2, O2 and N2). Low grade waste heat and water recovery using ceramic membrane, based on separation mechanism, is a promising technology which helps to increase the efficiency of boilers and gas or coal combustors. The effects of inclination angles of tube bundle, different flue gas velocities, and the mass flow rate of water and gas flue have been studied numerically on heat transfer, pressure drop and condensation rates. To assess the capability of single stage TMC heat exchangers in terms of waste heat and water recovery at various inlet conditions, a single phase multi-component model is used. ANSYS-FLUENT is used to simulate the heat and mass transfer inside TMC heat exchangers. The condensation model and related source/sink terms are implemented in the computational setups using appropriate User Defined Functions (UDFs).
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Duignan, Mark R., and Si Y. Lee. "Cross-Flow Ultrafiltration Scaling Considerations." In ASME 2006 2nd Joint U.S.-European Fluids Engineering Summer Meeting Collocated With the 14th International Conference on Nuclear Engineering. ASMEDC, 2006. http://dx.doi.org/10.1115/fedsm2006-98492.
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One legacy of the nuclear age is radioactive waste and it must be stabilized to be stored in a safe manner. An important part of the stabilization process is the separation of radioactive solids from the liquid wastes by cross-flow ultrafiltration. The performance of this technology with the wastes to be treated was unknown and, therefore, had to be obtained. However, before beginning a filter study the question of experimental scale had to be addressed. Of course, carrying out experiments using full-size equipment is always ideal, but rarely practical when dealing with plant size processes. Flow loops that will handle millions of liters of slurries, which are either highly caustic or acidic, with flow rates of 10,000 lpm make full-scale tests prohibitively expensive. Moreover, when the slurries happen to be radioactive such work is also very dangerous. All of these considerations lend themselves to investigations at smaller scales and in many situations can be treated with computational analyses. Unfortunately, as scale is reduced it becomes harder to provide prototypic results and the two and three phase multi-component mixtures challenge accurate computational results. To obtain accurate and representative filter results two smaller scale filters were chosen: 1. Small-scale – would allow the testing with actual radioactive waste samples and compare results with simulated wastes that were not radioactive. For this scale the feed tank held 6 liters of waste and it had a single cross-flow filter tube 0.61 m long. 2. Pilot-scale – would be restricted to use simulated non-radioactive wastes. At this larger scale the feed tank held 120 liters of waste and the filter unit was prototypic to the planned plant facility in pore size (0.1 micron), length (2.29 m), diameter (0.0127 m inside and 0.0159 m outside diameter), and being multi-tubed. The small-scale apparatus is convenient, easy to use, and can test both radioactive and non-radioactive wastes; therefore, there is a larger database than at the pilot scale. In fact, the small-scale data are very useful to compare actual waste to simulated waste filter performance to validate a simulant, but data availability does not mean they accurately represent full-scale performance. Results indicate that small-scale filter fluxes to be significantly higher that those at the pilot scale. In an attempt to study the difference in filter performance at the two scales an experiment was done that used exactly the same simultant which was created at the same time so that issues of composition and aging would not compromise the results. This paper will discuss those experimental results, as well as those from a computational fluid dynamics model to better understand the small-scale limitations.