Academic literature on the topic 'Mud/NuMA'

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Journal articles on the topic "Mud/NuMA"

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Bowman, Sarah K., Ralph A. Neumüller, Maria Novatchkova, Quansheng Du, and Juergen A. Knoblich. "The Drosophila NuMA Homolog Mud Regulates Spindle Orientation in Asymmetric Cell Division." Developmental Cell 10, no. 6 (2006): 731–42. http://dx.doi.org/10.1016/j.devcel.2006.05.005.

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Siller, Karsten H., Clemens Cabernard, and Chris Q. Doe. "The NuMA-related Mud protein binds Pins and regulates spindle orientation in Drosophila neuroblasts." Nature Cell Biology 8, no. 6 (2006): 594–600. http://dx.doi.org/10.1038/ncb1412.

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Ségalen, Marion, Christopher A. Johnston, Charlotte A. Martin, et al. "The Fz-Dsh Planar Cell Polarity Pathway Induces Oriented Cell Division via Mud/NuMA in Drosophila and Zebrafish." Developmental Cell 19, no. 5 (2010): 740–52. http://dx.doi.org/10.1016/j.devcel.2010.10.004.

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Capalbo, L., P. P. D'Avino, V. Archambault, and D. M. Glover. "Rab5 GTPase controls chromosome alignment through Lamin disassembly and relocation of the NuMA-like protein Mud to the poles during mitosis." Proceedings of the National Academy of Sciences 108, no. 42 (2011): 17343–48. http://dx.doi.org/10.1073/pnas.1103720108.

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Franco, Maribel, and Ana Carmena. "Eph signaling controls mitotic spindle orientation and cell proliferation in neuroepithelial cells." Journal of Cell Biology 218, no. 4 (2019): 1200–1217. http://dx.doi.org/10.1083/jcb.201807157.

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Mitotic spindle orientation must be tightly regulated during development and adult tissue homeostasis. It determines cell-fate specification and tissue architecture during asymmetric and symmetric cell division, respectively. Here, we uncover a novel role for Ephrin–Eph intercellular signaling in controlling mitotic spindle alignment in Drosophila optic lobe neuroepithelial cells through aPKC activity–dependent myosin II regulation. We show that conserved core components of the mitotic spindle orientation machinery, including Discs Large1, Mud/NuMA, and Canoe/Afadin, mislocalize in dividing Ep
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Ribeiro, Mariléa, and Abel Carrasquilla. "A NEW APPROACH TO CALCULATE MUD INVASION IN RESERVOIRS USING WELL LOGS." Revista Brasileira de Geofísica 32, no. 2 (2014): 215. http://dx.doi.org/10.22564/rbgf.v32i2.453.

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ABSTRACT. Muds of different compositions are used in the drilling well process, to support the wall of the borehole along with maintenance of pressure, and toremove rock cuttings generated from the geological formations encountered by the drill bit. The drilling mud invades the formations and modifies the zones surroundingthe borehole, mainly, in terms of the physical properties of the rocks, such as porosity and permeability. The identification of this formation damage is important forreservoir characterization, and the subsequent well completion, as well as for the analysis of economic viabi
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Kotak, Sachin. "Mechanisms of Spindle Positioning: Lessons from Worms and Mammalian Cells." Biomolecules 9, no. 2 (2019): 80. http://dx.doi.org/10.3390/biom9020080.

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Proper positioning of the mitotic spindle is fundamental for specifying the site for cleavage furrow, and thus regulates the appropriate sizes and accurate distribution of the cell fate determinants in the resulting daughter cells during development and in the stem cells. The past couple of years have witnessed tremendous work accomplished in the area of spindle positioning, and this has led to the emergence of a working model unravelling in-depth mechanistic insight of the underlying process orchestrating spindle positioning. It is evident now that the correct positioning of the mitotic spind
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Berends, Christian W. H., Javier Muñoz, Vincent Portegijs, et al. "F-actin asymmetry and the endoplasmic reticulum–associated TCC-1 protein contribute to stereotypic spindle movements in the Caenorhabditis elegans embryo." Molecular Biology of the Cell 24, no. 14 (2013): 2201–15. http://dx.doi.org/10.1091/mbc.e13-02-0076.

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The microtubule spindle apparatus dictates the plane of cell cleavage in animal cells. During development, dividing cells control the position of the spindle to determine the size, location, and fate of daughter cells. Spindle positioning depends on pulling forces that act between the cell periphery and astral microtubules. This involves dynein recruitment to the cell cortex by a heterotrimeric G-protein α subunit in complex with a TPR-GoLoco motif protein (GPR-1/2, Pins, LGN) and coiled-coil protein (LIN-5, Mud, NuMA). In this study, we searched for additional factors that contribute to spind
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Taniguchi, Kiichiro, Akihiko Kokuryo, Takao Imano, Ryunosuke Minami, Hideki Nakagoshi, and Takashi Adachi-Yamada. "Isoform-specific functions of Mud/NuMA mediate binucleation of Drosophilamale accessory gland cells." BMC Developmental Biology 14, no. 1 (2014). http://dx.doi.org/10.1186/s12861-014-0046-5.

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Parra, Amalia S., Cameron A. Moezzi, and Christopher A. Johnston. "Drosophila Adducin facilitates phase separation and function of a conserved spindle orientation complex." Frontiers in Cell and Developmental Biology 11 (August 16, 2023). http://dx.doi.org/10.3389/fcell.2023.1220529.

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Asymmetric cell division (ACD) allows stem cells to generate differentiating progeny while simultaneously maintaining their own pluripotent state. ACD involves coupling mitotic spindle orientation with cortical polarity cues to direct unequal segregation of cell fate determinants. In Drosophila neural stem cells (neuroblasts; NBs), spindles orient along an apical-basal polarity axis through a conserved complex of Partner of Inscuteable (Pins; human LGN) and Mushroom body defect (Mud; human NuMA). While many details of its function are well known, the molecular mechanics that drive assembly of
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Dissertations / Theses on the topic "Mud/NuMA"

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Darnat, Pénélope. "Cycline A, un nouveau lien entre cycle et popularité cellulaires." Electronic Thesis or Diss., Sorbonne université, 2020. http://www.theses.fr/2020SORUS293.

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Durant une division asymétrique (ACD), cycle et polarité cellulaires se coordonnent pour servir la diversité cellulaire. Dans le cas d’une ACD au sein d‘un épithélium, la Polarité Cellulaire Planaire, menée par Frizzled (Fz) et Dishevelled (Dsh), oriente la cellule mère et le fuseau mitotique et induit une polarité qui va permettre l’alignement et la répartition des déterminants cellulaires entre les cellules filles. Dans ce contexte, mon sujet de thèse vise à étudier les liens entre cycle et polarité dans le modèle du lignage des soies de la drosophile, où depuis l’ACD de la cellule précurseu
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