Relevant bibliographies by topics / Mucosa Orale

Academic literature on the topic 'Mucosa Orale'

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Published: 11 March 2023

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Journal articles on the topic "Mucosa Orale"

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Attuati, Sara, Valeria Martini, Riccardo Mauro Bonacina, and Umberto Mariani. "Neoformazione ulcerata della mucosa orale." Dental Cadmos 87, no. 04 (April 2019): 197. http://dx.doi.org/10.19256/d.cadmos.04.2019.03.

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Di Iorio, E. "Lesione esofitica della mucosa orale." Dental Cadmos 85, no. 06 (June 2017): 327. http://dx.doi.org/10.19256/d.cadmos.06.2017.04.

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Beauvillain de Montreuil, C., M. H. Tessier, and J. Billet. "Patologia benigna della mucosa orale." EMC - Otorinolaringoiatria 11, no. 3 (September 2012): 1–20. http://dx.doi.org/10.1016/s1639-870x(12)62051-0.

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Beauvillain de Montreuil, C., M. H. Tessier, and J. Billet. "Patologia benigna della mucosa orale." EMC - Otorinolaringoiatria 18, no. 2 (June 2019): 1–23. http://dx.doi.org/10.1016/s1639-870x(19)42040-0.

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Di lorio, E. "Pigmentazioni multiple della mucosa orale." Dental Cadmos 83, no. 7 (September 2015): 443–44. http://dx.doi.org/10.1016/s0011-8524(15)30062-3.

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Baart, J. A. "Oral medicine 6. Ulceraties van de orale mucosa." Nederlands Tijdschrift voor Tandheelkunde 120, no. 05 (May 10, 2013): 246–49. http://dx.doi.org/10.5177/ntvt.2013.05.12242.

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Grande, Francesco, and Claudio Marchetti. "Bolle ematiche ricorrenti sulla mucosa orale." Dental Cadmos 87, no. 01 (September 2019): 541. http://dx.doi.org/10.19256/d.cadmos.09.2019.03.

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MORO, A., C. DE WAURE, F. DI NARDO, F. SPADARI, M. D. MIGNOGNA, M. GIULIANI, L. CALIFANO, et al. "Il dispositivo medico GOCCLES® è in grado di individuare displasie e cancro orale se impiegato nel setting odontoiatrico. Risultati da uno studio multicentrico." Acta Otorhinolaryngologica Italica 35, no. 6 (December 2015): 449–54. http://dx.doi.org/10.14639/0392-100x-922.

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Scopo di questo studio è dimostrare che il dispositivo medico GOCCLES® permette di condurre l’esame dell’autofluorescenza del cavo orale nel setting odontoiatrico. Si tratta di uno studio multicentrico non randomizzato su pazienti consecutivi a rischio di cancro orale. I pazienti sono stati sottoposti ad ispezione del cavo orale ad occhio nudo seguita dall’esame dell’autofluorescenza condotto indossando gli occhiali GOCCLES® mentre una lampada fotopolimerizzante illuminava la mucosa orale. Le lesioni sono state definite come qualunque lesione precancerosa del cavo orale visibile ad occhio nudo o area di perdita di fluorescenza visibile con GOCCLES®. Tutte le lesioni persistenti sono state sottoposte a biopsia escissionale o incisionale. Sono stati reclutati 61 pazienti e analizzati i dati da 64 lesioni. Delle 62 lesioni identificate dal dispositivo, 31 erano veramente positive. Il dispositivo ha identificato 31 delle 32 lesioni veramente positive. Una lesione (un carcinoma invasivo) non era visibile ad occhio nudo. Tutte le lesioni classificate come displasia tra moderata e severa e ogni carcinoma sono stati correttamente identificati dal dispositivo. Nel Il 56,7% delle lesioni identificate dal dispositivo mostrava margini più ampi rispetto a quelli visibili ad occhio nudo. Il dispositivo medico GOCCLES® permette di osservare il fenomeno della perdita di fluorescenza in pazienti affetti da displasia o cancro del cavo orale. Ha permesso di effettuare l’esame dell’autofluorescenza con ciascuna lampada fotopolimerizzante testata. I risultati suggeriscono di impiegare GOCCLES® come esame complementare rispetto all’ispezione ad occhio nudo del cavo orale su pazienti a rischio per cancro orale. Il dispositivo permette di identificare lesioni altrimenti visibili o i cui margini sono sottostimati dall’ispezione ad occhio nudo.
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Rooijers, W. "Medicaments and oral healthcare. Adverse effects of medications on the oral mucosa." Nederlands Tijdschrift voor Tandheelkunde 127, no. 07/08 (July 3, 2020): 434–40. http://dx.doi.org/10.5177/ntvt.2020.07/08.20007.

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Meleti, M., B. Bianchi, E. Merigo, M. Manfredi, R. Guidotti, C. Fornaini, A. Sarraj, G. Mergoni, L. Corcione, and P. Vescovi. "Pigmentazioni maculari acquisite delle labbra e della mucosa orale." Dental Cadmos 79, no. 2 (February 2011): 59–60. http://dx.doi.org/10.1016/j.cadmos.2010.11.001.

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Dissertations / Theses on the topic "Mucosa Orale"

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Kinikoglu, Fatma Beste. "Tissue engineering of full-thickness human oral mucosa." Thesis, Lyon 1, 2010. http://www.theses.fr/2010LYO10310.

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L’ingénierie de la muqueuse orale humaine (MOH) a pour but le comblement des pertes de substances suite à un traumatisme facial ou à la chirurgie des lésions malignes. Elle a aussi des applications en recherche pour élucider les mécanismes biologiques de la MO et en pharmacotoxicologie comme alternative à l’expérimentation animale. L'objectif de cette thèse était de reconstruire une MOH proche du tissu normal. À cette fin, la faisabilité du concept a d'abord été testée par co-culture de fibroblastes de la lamina propria et de cellules épithéliales de MOH dans le substrat de collagène-chitosan glycosaminoglycane, développé pour la production de peaux reconstruites. La caractérisation de la MOH reconstruite par histologie, immunohistochimie et microscopie électronique à transmission a montré la présence d’une LP équivalente avec un épithélium pluristratifié et non kératinisé très proche du tissu d’origine. Grâce à ce modèle, nous avons ensuite démontré que l’origine des fibroblastes (MO, cornée, peau) influence significativement l’épaisseur et l’ultrastructure de l'épithélium obtenu par culture de cellules épithéliales orales. Enfin, afin d'améliorer les propriétés adhésives du substrat à base collagène, nous avons ajouté au collagène, une élastine-like recombinante (ELR) contenant le tri-peptide d’adhésion cellulaire, RGD, et produit un nouveau substrat bicouche, poreux par lyophilisation et recouvert d’une couche fibreuse par électrofilage. Ces substrats ont été caractérisés par porosimétrie au mercure, microscopie électronique à balayage et essais mécaniques. Nous avons démontré l’effet stimulant de ELR sur la prolifération des fibroblastes et des cellules épithéliales
Tissue engineered human oral mucosa has the potential to fill tissue deficits caused by facial trauma or malignant lesion surgery. It can also help elucidate the biology of oral mucosa and serve as an alternative to in vivo testing of oral care products. The aim of this thesis was to construct a tissue engineered full-thickness human oral mucosa closely mimicking the native tissue. To this end, the feasibility of the concept was tested by co-culturing fibroblasts and epithelial cells isolated from normal human oral mucosa biopsies in a collagen-glycosaminoglycan-chitosan scaffold, developed in our laboratory to construct a skin equivalent. An oral mucosal equivalent closely mimicking the native one was obtained and characterized by histology, immunohistochemistry and transmission electron microscopy. Using the same model, the influence of mesenchymal cells on oral epithelial development was investigated by culturing epithelial cells on lamina propria, corneal stroma and dermal equivalents. They were found to significantly influence the thickness and the ultrastructure of the epithelium. Finally, in order to improve the adhesiveness of conventional scaffolds, an elastin-like recombinamer (ELR) containing the cell adhesion tripeptide, RGD, was used in the production of novel bilayer scaffolds employing lyophilization and electrospinning. These scaffolds were characterized by mercury porosimetry, scanning electron microscopy and mechanical testing. In vitro tests revealed positive contribution of ELR on the proliferation of both fibroblasts and epithelial cells. It was thus possible to construct a viable oral mucosa equivalent using the principles of tissue engineering
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Gualerzi, A. "ANALISI MORFOLOGICA DELLA MUCOSA ORALE CHERATINIZZATA UMANA NORMALE DOPO ESPOSIZIONE A STIMOLI ESOGENI." Doctoral thesis, Università degli Studi di Milano, 2013. http://hdl.handle.net/2434/215122.

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Cigarette smoke and alendronate are two different exogenous stimuli involved in the pathogenesis of oral diseases, but their actual role in altering the epithelial barrier and function has not been thoroughly investigated, yet. To evaluate the morphological chronic effect of both agents, biopsies of normal human keratinized oral mucosa are collected respectively from smoking women (n = 5) and from osteoporotic women undergoing chronic oral therapy with alendronate (n = 6). Both groups are compared to age and sex-matched controls. The acute effects of smoke are investigated in a three-dimensional model of human oral mucosa organotypic cultures (n = 5) after exposure to the mainstream smoke coming from one single cigarette. Morphological analysis by light and transmission electron microscopy is performed on all considered samples. Chronic smoke and chronic alendronate treatment affect keratinocyte terminal differentiation and intercellular adhesion impairing desmosomal molecular composition and morphology, in a stress specific and time exposure related manner. Desmoglein 3 and desmoglein 1 distribution are altered respectively after chronic smoke and chronic alendronate treatment. Epithelial proliferation is also impaired in the alendronate treated group. On the contrary, after three hours from cigarette smoke exposure, the first significant response of the oral epithelium comes from the immediately suprabasal keratinocytes, without impairment of the epithelial junctional apparatus and apoptosis induction. The collected data highlight differences in the acute and chronic response of the oral epithelium to cigarette smoke. Moreover, reported results support the crucial signaling role of desmosomal cadherins in the oral epithelium and introduce a new issue in oral biology: the specific response of human oral mucosa to different physico-chemical stresses.
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Ployon, Sarah. "Interactions entre muqueuse orale, salive et molécules de la flaveur." Thesis, Dijon, 2016. http://www.theses.fr/2016DIJOS037/document.

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Le rôle de la salive dans la perception sensorielle est de plus en plus reconnu, notamment par le biais des interactions physico-chimiques pouvant s’établir entre protéines salivaires et constituants alimentaires. Ce travail s’intéresse à la pellicule salivaire, la couche de protéines salivaires ancrées aux cellules épithéliales, et vise à caractériser les interactions pouvant s’établir d’une part entre ces protéines et épithélium oral, et d‘autre part entre ces protéines et les molécules de la flaveur. Pour cela, un modèle in vitro de muqueuse orale a été développé. Une lignée cellulaire stable (TR146/MUC1) a été obtenue par transfection de la lignée cellulaire TR146 de manière à exprimer la mucine membranaire MUC1. Afin de former une pellicule salivaire, les cellules confluentes ont été incubées avec de la salive humaine. La rétention des mucines salivaires MUC5B par les cellules TR146/MUC1 est augmentée par rapport aux TR146, apportant ainsi un argument en faveur de l’implication de MUC1 dans l’ancrage des MUC5B aux cellules épithéliales. Le modèle développé a été appliqué à l’étude des interactions entre la muqueuse orale et les molécules d’arôme et les tanins. L’analyse des coefficients de partage par GC-FID a mis en évidence 1- l’importance de l’hydratation de la muqueuse sur la libération des composés les plus hydrophiles, 2- la capacité des cellules à métaboliser certaines molécules d’arôme, 3- l’absence d’effet de la pellicule sur la libération des molécules d’arôme à l’équilibre. En revanche, l’analyse par PTR-MS a révélé un effet de la muqueuse et de la pellicule sur la cinétique de libération des molécules d’arôme. Les interactions entre les protéines de la pellicule salivaire et les tanins modifient les caractéristiques structurales de la pellicule, en particulier le tapissage des cellules par les MUC5B. Les possibles implications sensorielles, respectivement dans les phénomènes de persistance aromatique et d’astringence, sont discutées
The role of saliva in food sensory perception is increasingly recognized, especially through physicochemical interactions occurring between salivary proteins and food components. This work focuses on the mucosal pellicle, a layer of salivary proteins anchored onto epithelial cells, and aims at characterizing interactions that may occur between the proteins of the mucosal pellicle and flavour compounds. For that purpose, an in vitro model of oral mucosa was developed. A stable cell line (TR146/MUC1) was obtaining by transfecting the TR146 cell line in order to express the membrane bound mucin MUC1. In order to form a salivary pellicle, confluent cells were incubated with human saliva. A higher retention of salivary MUC5B by TR146/MUC1 cells was observed compared to TR146 cells, emphasising the involvement of MUC1 in MUC5B anchoring to epithelial cells. The model was applied to the investigation of interactions between the oral mucosa and aroma molecules and tannins. Measurements of partition coefficients by GC-FID revealed 1- the role of hydration of the mucosa on the release of the most hydrophilic compounds, 2- the ability of cells to metabolize some aroma compounds, 3- the absence of effect of the mucosal pellicle itself on aroma release at the thermodynamic equilibrium. Oppositely, analyses by PTR-MS evidenced an effect of the mucosa and of the pellicle on aroma release kinetic. Interactions between proteins of the mucosal pellicle and tannins modified structural characteristics of the pellicle, especially the coating of cells by salivary MUC5B. Sensory relevance for the phenomena of aroma persistence and astringency, respectively, are discussed
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GIOVANNACCI, ILARIA. "Quantificazione spettrofotometrica dell'autofluorescenza come potenziale strumento diagnostico per lesioni maligne della cute e della mucosa orale." Doctoral thesis, Università degli studi di Modena e Reggio Emilia, 2020. http://hdl.handle.net/11380/1211519.

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L'autofluorescenza (AF) è definita come l'emissione di fluorescenza osservata quando determinate molecole sono eccitate da raggi UV o luce visibile di lunghezze d'onda adeguate. Quando una molecola viene illuminata ad una lunghezza d'onda di eccitazione, assorbirà questa energia e verrà attivata dal suo stato fondamentale a quello eccitato. La molecola (fluoroforo) può quindi rilassarsi dallo stato eccitato a fondamentale generando energia sotto forma di fluorescenza, a lunghezze d'onda di emissione più lunghe di quella di eccitazione. I fluorofori endogeni sono molecole ampiamente distribuite in cellule e tessuti, come proteine ​​contenenti aminoacidi aromatici, flavine e lipopigmenti. I principali fluorofori della cute sana si trovano nell'epitelio (ad es. cheratina, nicotinamide adenine dinucleotide o NADH e flavin adenine dinucleotide o FAD) e nella sottomucosa (ad es. collagene ed elastina). Queste molecole, quando irradiate tra le lunghezze d'onda da 375 a 440 nm, mostrano fluorescenza nell'intervallo spettrale del verde. Il non-melanoma skin cancer (NMSC) è il tumore maligno più comune al mondo. Lo sviluppo dei NMSC è accompagnato da cambiamenti istopatologici nell'epidermide come perdita di maturazione cellulare, alterazione della produzione di cheratina, ispessimento generale dello strato epiteliale e alterazioni biochimiche (riduzione del NADH). I NMSC sono anche accompagnati da cambiamenti istopatologici nello stroma e nella sottomucosa sottostanti, tra cui la neovascolarizzazione e la distruzione del legame crociato di collagene da parte delle proteasi. Queste alterazioni portano ad una generale riduzione dell’AF dovuta all'alterazione della distribuzione dei fluorocromi e in particolare al NADH e al collagene. Negli ultimi due decenni, gli studi riguardanti ll’AF cellulare e tissutale hanno avuto un notevole aumento. Sono stati condotti studi sull’AF sia in vitro che in vivo, per lo studio dei tessuti normali e per la discriminazione tra tessuti normali e lesioni neoplastiche di mucosa orale, cute, esofago, colon, polmone, bronchi, cervello e vescica. I metodi utilizzati sono sia il direct visual fluorescence examination (DVFE) sia lo spettrofotometria. In particolare, il DVFE è stato ampiamente utilizzato per studi clinici sulla mucosa orale. Per quanto riguarda l’AF della cute, questa è stata studiata più frequentemente usando lo spettrofotometria. Il principio è la scansione e l'analisi della luce emessa dalla cute dopo l'esposizione a una fonte di luce attivante. Tuttavia, ad oggi non sono emersi metodi che fossero traducibili nella pratica clinica. L'obiettivo principale di questo studio è quello di analizzare la correlazione tra la misurazione spettrale dell’AF cutanea e le caratteristiche istopatologiche della cute maligna e pre-maligna nel campo dei NMSC. Dopo la rimozione chirurgica, verrà eseguita una valutazione ex vivo dell’AF. Il campione verrà irradiato con una sonda che emette una luce nello spettro blu (lunghezza d'onda 400-440 nm) e la fluorescenza emessa dal tessuto verrà misurata mediante uno spettrofotometro in modalità spot standardizzata. Eventuali modifiche rilevate verranno riportate sul campione chirurgico con l'applicazione di un repere. Verrà eseguito un esame istopatologico della lesione e eventuali cambiamenti nel pattern di fluorescenza saranno correlati con possibili alterazioni del pattern istopatologico, facendo riferimento ai reperi chirurgici. Le alterazioni delle misure spettrali sono correlate alle alterazioni istopatologiche dei NMSC. La misurazione spettrale può essere un nuovo supporto per la diagnosi precoce dei NMSC, una guida per le biopsie incisionali mirate, uno strumento per la definizione dei margini chirurgici intraoperatori e per il follow-up dei pazienti trattati.
Autofluorescence (AF) is defined as the fluorescence emission observed when certain cell molecules are excited by UV or visible light of suitable wavelenghts. When a biologic molecule is illuminated at an excitation wavelength within the absorption spectrum of that molecule, it will absorb this energy and be activated from its ground state to an excited state. The molecule (fluorophore) can then relax back from the excited to the ground state by generating energy in the form of fluorescence, at emission wavelengths, which are longer than that of the excitation wavelength. The most important endogenous fluorophores are molecules widely distributed in cells and tissues, like proteins containing aromatic aminoacids, flavins and lipopigments. The main fluorophores of healthy skin are located in the epithelium (eg. keratin, nicotinamide adenine dinucleotide or NADH and flavin adenine dinucleotide or FAD) and the submucosa (e.g. collagen and elastin). These molecules when irradiated between the wavelengths from 375 and 440 nm, show fluorescence in the green spectral range. Nonmelanoma skin cancer (NMSC) is the most common malignancy worldwide. The developement of NMSC is accompanied by histopathological changes in epidermis such as loss of cellular maturation, alteration in keratin production, overall thickening of the epithelial layer and biochemical alterations (NADH decrease). NMSC is also accompanied by histopathological changes in the underlying stroma and submucosa, including neovascularization and destruction of the collagen cross-link by proteases. These alterations lead to a general decrease in AF due the alteration in distribution of the fluorochromes and in particular to NADH and collagen. In the last two decades, studies concerning cell and tissue AF has had a dramatic increase. AF studies have been performed both in vitro and in vivo, for the study of normal tissue and for the discrimination between normal tissues and neoplastic lesions of oral mucosa, skin, esophagus, colon, lung, bronchi, brain and bladder. The methods used are both direct visual fluorescence examination (DVFE) and spectrophotometry. In particular, DVFE has been widely used for clinical studies on oral mucosa. Regarding AF of the skin, this has been studied more frequently by using spectrophotometry. The principle is scanning and analyzing reflected light from the skin after exposure to an activating light source. AF spectroscopy is a very sensitive technique for quantitative measurements of tissue constituents. However, to date no methods have emerged that can be translated into clinical practice. The primary objective of this study is to investigate the correlation between spectral mesurement of cutaneous AF and the histopathological characteristics of malignant and pre-malignant skin in NMSC. Following surgical removal of the cancer, an ex vivo evaluation of the AF will be performed. The specimen will be irradiated with a probe that emits a light in the blue spectrum (wavelength 400-440 nm) and the fluorescence emitted by the tissue will be measured using a spectrophotometer in a standardized spot modality. Any changes detected will be reported on the surgical specimen with the application of a surgical mark. Histopathological examination of the lesion will be performed and any changes in the fluorescence pattern will be correlated with possible alterations in the histopathological pattern, referring to surgical marks. Alterations in AF spectral measurement correlate with histopathological alterations in NMSC. the spectral measurement can be a new support for the early diagnosis of NMSCs, a guide for the targeted incisional biopsies, a tool for the definition of the intraoperative surgical margins, and for the follow-up of treated patients.
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Ruberti, Maristela 1975. "Caracterização fenotípica e funcional das células imunocompetentes da mucosa intestinal envolvidas na tolerância oral a ovalbumina." [s.n.], 2012. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317404.

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Orientador: Wirla Maria da Silva Cunha Tamashiro
Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia
Made available in DSpace on 2018-08-20T10:43:40Z (GMT). No. of bitstreams: 1 Ruberti_Maristela_D.pdf: 10774061 bytes, checksum: 7afe7ee8aa8c7f97c1f80e66f0cd8bfa (MD5) Previous issue date: 2012
Resumo: Trabalhos anteriores de nosso laboratório mostraram que camundongos transgênicos DO11.10, cuja maioria dos linfócitos T expressam TCR específico para ovalbumina (OVA) no contexto de...Observação: O resumo, na íntegra, poderá ser visualizado no texto completo da tese digital
Abstract: Previous work from our laboratory showed that DO11.10 transgenic mice, in which the most of T lymphocytes express TCR specific for ovalbumin (OVA) in the context of...Note: The complete abstract is available with the full electronic document
Doutorado
Imunologia
Doutor em Genetica e Biologia Molecular
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WACHSMANN, LEVY DOMINIQUE. "Immunite des muqueuses : etude de la reponse immune locale apres stimulation orale par des antigenes proteiques et polysaccharidiques de streptococcus mutans." Strasbourg 1, 1986. http://www.theses.fr/1986STR13125.

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Said, Zulfahmi. "Analysis of corticosteroid drug delivery using tissue engineered oral mucosa for the treatment of inflammatory mucosal diseases." Thesis, University of Sheffield, 2018. http://etheses.whiterose.ac.uk/22529/.

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Introduction: Tissue-engineered oral mucosa (TEOM) is increasingly being used to assess drug delivery and toxicity, as well as for modeling oral diseases. Current TEOM models are constructed using primary oral fibroblasts and keratinocytes that display donor-to-donor variability and whose widespread use is restricted by availability and ethic limitations. To address these issues, an attractive approach is the development of TEOM using immortalised cells. Aim: This study aimed to construct and characterise TEOM based on TERT2-immortalised oral keratinocytes (FNB6) cells and use these TEOM to assess the toxicity and delivery of corticosteroids using a novel electrospun-based oral patch. Methods: TEOM were constructed by culturing immortalised FNB6 oral keratinocytes on top of a normal oral fibroblast (NOF)-populated collagen type 1 hydrogel in tissue culture transwell inserts at an air-to-liquid interface (ALI) for up to 14 days. The TEOM were characterised using histological, immunohistological, ultrastructural (TEM), tissue viability (AlamarBlue), trans-electrical resistance (TEER), and permeability (FITC-dextran) analysis. Cytotoxicity assessment of seven corticosteroids was performed using MTT assay on monolayer cultures (FNB6 and NOF cells) and TEOM. Novel mucoadhesive bilayer patches containing clobetasol 17-propionate (CP) were subjected to morphological, physicochemical, drug release, swelling and cytotoxicity analysis. In vitro permeation studies of the corticosteroids against TEOM was measured using HPLC. The immunosuppressive effect of delivered CP against activated Jurkat T-cells was assessed by measuring changes in interleukin-2 (IL-2) release. Results: Histologically, TEOM mimicked native oral mucosa displaying a stratified epithelium, fibroblast-containing connective tissue and basement membrane. IHC revealed the expression markers for differentiation (cytokeratin 4,13,14), proliferation (Ki-67), cell adhesion (E-cadherin, claudin-4). Furthermore, TEM confirmed the presence of desmosomes and hemidesmosomes in the epithelium. Maximal TEOM viability was found up to day 25 and maximal TEER value was exhibited at day 20 (155.8 Ω.cm2). Permeability analysis showed that only small molecules (3 kDa) could pass through the epithelium. Differential drug sensitivity of corticosteroids against monolayer cultures was ranked as follow; CP > BU > BD > BV > TA > HV > HB by IC50 value, and this was similar for TEOM although IC50 values were higher for 3D models. Novel mucoadhesive bilayer patches containing CP exhibited good physicochemical characteristics and drug release profiles. Toxicity testing to the OECD standard revealed that patch delivered CP was considered a non-irritant. Oral mucosal delivered CP using liquid or patch formulation into the TEOM tissue or receptive medium was both dose and time-dependent. In addition, both liquid and patch delivered CP significantly reduced the secretion of IL-2 by activated Jurkat T cells in a TEOM model replicating an oral inflammatory disease. Conclusion: FNB6 TEOM models are able to mimic the native oral mucosa and have the potential to be used for drug delivery and toxicity evaluation. Oral patch-delivered CP was able to cross the TEOM and inhibit the IL-2 secretion of activated T cells, suggesting that this mode of drug delivery could be used to treat oral inflammatory diseases.
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Sukotjo, Cortino. "Wit 3.0, a novel gene derived from edentulous oral mucosa, encodes cytoplasmic molecules facilitating oral mucosa wound contraction." Restricted to subscribing institutions, 2002. http://proquest.umi.com/pqdweb?did=1568361991&sid=1&Fmt=2&clientId=1564&RQT=309&VName=PQD.

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Fonollosa, Pla José María. "Influencia del monómero residual, el diseño y la falta de ajuste de las prótesis dentales con soporte mucoso, en las lesiones de la mucosa oral." Doctoral thesis, Universitat Autònoma de Barcelona, 2021. http://hdl.handle.net/10803/671700.

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Introducció. La patologia de la mucosa oral inclou lesions i alteracions relacionades amb l'ús de pròtesis dentals de suport mucós elaborades amb materials acrílics, tant recents com antigues. La seva etiologia pot ser degut a l'traumatisme d'un mal ajust o disseny que no aconsegueix transmetre de forma homogènia les forces oclusals i / o genera friccions, contactes i sobrepressions, sobre la mucosa oral i els teixits tous adjacents. En altres ocasions seran els elements químics dels materials els responsables de determinades reaccions mucoses, tant per restes de monòmer lliure com d'altres compostos de les resines acríliques. Les hipòtesis de treball, d'una banda, apunten cap als dissenys incorrectes ia la falta d'ajust com a possibles causes de determinades lesions a la mucosa oral i, de l'altra, a les tècniques aplicables als sistemes de processat de l'material acrílic autopolimeritzable per reduir la presència de monòmer residual i, en conseqüència, evitar reaccions que poden generar una estomatitis al·lèrgica de contacte en el pacient. Objectiu. Determinar la relació entre les lesions dels teixits bucals d'etiologia protèsica, en pacients portadors de pròtesis dentals completes, amb aspectes del seu disseny, de la seva falta d'ajust i amb els procediments de polimerització dels materials acrílics amb què es fabriquen. Mètode. S'ha realitzat un estudi observacional, descriptiu, transversal, de sèrie de casos, prevalents, per tant retrospectiu, en pacients portadors de pròtesis dentals completes, completes unimaxil·lars i parcials removible classe I i II de Kennedy Resultats. Sobre 144 pacients s'han analitzat 288 pròtesis superiors i inferiors que han originat lesions agudes i cròniques en un 18,40% per disseny incorrecte i en un 12,15% per falta d'ajust. Les resines autopolimerizables amb tractament durant i després de la polimerització no han generat estomatitis al·lèrgica de contacte en 25 pacients amb pròtesis completes - 50 pròtesi-, 59 pacients amb pròtesi completa unimaxilar i 154 pròtesis parcials classe I i II de Kennedy. Conclusió. El disseny incorrecte i la falta d'ajust de les pròtesis completés estan relacionats amb algunes lesions de la mucosa oral. El tractament tèrmic i hídric en les resines autopolimerizables durant i després de la seva polimerització ha resultat eficaç per evitar la presència de estomatitis al·lèrgica de contacte.
Introducción. La patología de la mucosa oral incluye lesiones y alteraciones relacionadas con el uso de prótesis dentales de soporte mucoso elaboradas con materiales acrílicos, tanto recientes como antiguas. Su etiología puede deberse al traumatismo de un mal ajuste o diseño que no consigue transmitir de forma homogénea las fuerzas oclusales y/o genera roces, contactos y sobrepresiones, sobre la mucosa oral y los tejidos blandos adyacentes. En otras ocasiones serán los elementos químicos de los materiales los responsables de determinadas reacciones mucosas, tanto por restos de monómero libre como de otros compuestos de las resinas acrílicas. Las hipótesis de trabajo, por un lado, apuntan hacia los diseños incorrectos y a la falta de ajuste como posibles causas de determinadas lesiones en la mucosa oral y, por otro, a las técnicas aplicables a los sistemas de procesado del material acrílico autopolimerizable para reducir la presencia de monómero residual y, en consecuencia, evitar reacciones que pueden generar una estomatitis alérgica de contacto en el paciente. Objetivo. Determinar la relación entre las lesiones de los tejidos bucales de etiología protésica, en pacientes portadores de prótesis dentales completas, con aspectos de su diseño, de su falta de ajuste y con los procedimientos de polimerización de los materiales acrílicos con los que se fabrican. Método. Se ha realizado un estudio observacional, descritivo, transversal, de serie de casos, prevalentes, por lo tanto retrospectivo, en pacientes portadores de prótesis dentales completas, completas unimaxilares y parciales removible clase I y II de Kennedy Resultados. Sobre 144 pacientes se han analizado 288 prótesis superiores e inferiores que han originado lesiones agudas y crónicas en un 18,40% por diseño incorrecto y en un 12,15 % por falta de ajuste. Las resinas autopolimerizables con tratamiento durante y después de la polimerización no han generado estomatitis alérgica de contacto en 25 pacientes con prótesis completas - 50 prótesis-, 59 pacientes con prótesis completa unimaxilar y 154 prótesis parciales clase I y II de Kennedy. Conclusión. El diseño incorrecto y la falta de ajuste de las prótesis completase están relacionados con algunas lesiones de la mucosa oral. El tratamiento térmico e hídrico en las resinas autopolimerizables durante y después de su polimerización ha resultado eficaz para evitar la presencia de estomatitis alérgica de contacto.
Introduction. The pathology of the oral mucosa includes injuries and alterations related to the use of mucosal-bearing dental prostheses made with acrylic materials, both recent and old. Its etiology may be due to the trauma of a poor fit or design that fails to transmit the occlusal forces in a homogeneous way and / or generates friction, contacts and overpressures on the oral mucosa and adjacent soft tissues. On other occasions, the chemical elements of the materials will be responsible for certain mucosal reactions, both due to free monomer residues and other compounds of acrylic resins. The working hypotheses, on the one hand, point to incorrect designs and a lack of fit as possible causes of certain lesions in the oral mucosa and, on the other, to the techniques applicable to the processing systems of self-curing acrylic material to reduce the presence of residual monomer and, consequently, avoid reactions that can generate allergic contact stomatitis in the patient. Objective. To determine the relationship between oral tissue injuries of prosthetic etiology, in patients with complete dental prostheses, with aspects of their design, their lack of fit and with the polymerization procedures of the acrylic materials with which they are manufactured. Method. An observational, descriptive, cross-sectional, case series study, prevalent, therefore retrospective, has been carried out in patients with complete, complete unimaxillary and partial removable Kennedy class I and II dental prostheses. Results. Out of 144 patients, 288 upper and lower prostheses have been analyzed that have caused acute and chronic injuries in 18.40% due to incorrect design and in 12.15 % due to lack of adjustment. Self-curing resins with treatment during and after polymerization have not generated allergic contact stomatitis in 25 patients with complete dentures - 50 dentures -, 59 patients with unimaxillary full dentures, and 154 Kennedy class I and II partial dentures. Conclusion. Incorrect design and poor fit of complete dentures are related to some lesions of the oral mucosa. Heat and water treatment of self-curing resins during and after polymerization has been effective in preventing the presence of allergic contact stomatitis.
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Gibson, Rachel J. "Chemotherapy-induced mucositis : mechanisms of damage, time course of events and possible preventative strategies /." Title page, table of contents and abstract only, 2004. http://web4.library.adelaide.edu.au/theses/09PH/09phg4481.pdf.

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Books on the topic "Mucosa Orale"

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Squier, Christopher, and Kim A. Brogden, eds. Human Oral Mucosa. West Sussex, UK: John Wiley & Sons, Ltd., 2011. http://dx.doi.org/10.1002/9781118710470.

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Morteau, Olivier. Oral tolerance: The response of the intestinal mucosa to dietary antigens. Georgetown, Tex: Landes Bioscience/Eurekah.com, 2004.

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Morteau, Olivier. Oral tolerance: The response of the intestinal mucosa to dietary antigens. Georgetown, Tex: Landes Bioscience/Eurekah.com, 2004.

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Morteau, Olivier. Oral tolerance: The response of the intestinal mucosa to dietary antigens. Georgetown, TX: Landes Bioscience, 2001.

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Squier, Christopher A. Human oral mucosa: Development, structure, and function. Chichester, West Sussex, UK: Wiley-Blackwell, 2011.

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Schmidt, Enno, ed. Diseases of the Oral Mucosa. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-82804-2.

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1921-, Pindborg J. J., and Wahi P. N, eds. Histological typing of cancer and precancer of the oral mucosa. 2nd ed. Berlin: Springer, 1997.

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Bergmeier, Lesley Ann, ed. Oral Mucosa in Health and Disease. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-56065-6.

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Vedtofte, Poul. Cellemembranbundne kulhydrater i humant oralt epitel: Blodtypeantigener og lektinreceptorer som differentieringsmarkører i epitel fra mundslimhinde, tandanlæg, odontogene cyster og ameloblastomer. København: Institutterne for tand-, mund- og kæbekirurgi samt patologi og medicin, Københavns tandlægehøjskole og Afdelingen for tand-, mund- og kæbesygdomme, Rigshospitalet, 1986.

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Günther, Veltman, Loevy Hannelore Taschini, and Taschini Pierangelo, eds. Differential diagnosis of diseases of the oral mucosa. Chicago: Quintessence Pub. Co., 1989.

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Book chapters on the topic "Mucosa Orale"

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Allam, Jean-Pierre, and Natalija Novak. "Mucosal Homeostasis of the Oral Mucosa." In Oral Mucosa in Health and Disease, 69–76. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-56065-6_5.

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Squier, Christopher, and Kim A. Brogden. "Oral Epithelium." In Human Oral Mucosa, 19–52. West Sussex, UK: John Wiley & Sons, Ltd., 2013. http://dx.doi.org/10.1002/9781118710470.ch3.

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Squier, Christopher, and Kim A. Brogden. "Homologies in Structure and Function Among Mucosae: Oral, Esophageal, and Vaginal Mucosa." In Human Oral Mucosa, 145–57. West Sussex, UK: John Wiley & Sons, Ltd., 2013. http://dx.doi.org/10.1002/9781118710470.ch9.

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Lucas, R. B., and J. W. Eveson. "The Oral Mucosa." In Atlas of Oral Pathology, 47–65. Dordrecht: Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-009-5580-6_5.

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Squier, Christopher, and Kim A. Brogden. "The Functions of Oral Mucosa." In Human Oral Mucosa, 1–7. West Sussex, UK: John Wiley & Sons, Ltd., 2013. http://dx.doi.org/10.1002/9781118710470.ch1.

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Squier, Christopher, and Kim A. Brogden. "The Organization of Oral Mucosa." In Human Oral Mucosa, 9–17. West Sussex, UK: John Wiley & Sons, Ltd., 2013. http://dx.doi.org/10.1002/9781118710470.ch2.

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Squier, Christopher, and Kim A. Brogden. "The Interface Between Epithelium and Connective Tissue." In Human Oral Mucosa, 53–58. West Sussex, UK: John Wiley & Sons, Ltd., 2013. http://dx.doi.org/10.1002/9781118710470.ch4.

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Squier, Christopher, and Kim A. Brogden. "Connective Tissue." In Human Oral Mucosa, 59–75. West Sussex, UK: John Wiley & Sons, Ltd., 2013. http://dx.doi.org/10.1002/9781118710470.ch5.

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Squier, Christopher, and Kim A. Brogden. "Regional Differences in the Oral Mucosa." In Human Oral Mucosa, 77–98. West Sussex, UK: John Wiley & Sons, Ltd., 2013. http://dx.doi.org/10.1002/9781118710470.ch6.

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Squier, Christopher, and Kim A. Brogden. "Development and Aging of the Oral Mucosa." In Human Oral Mucosa, 99–111. West Sussex, UK: John Wiley & Sons, Ltd., 2013. http://dx.doi.org/10.1002/9781118710470.ch7.

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Conference papers on the topic "Mucosa Orale"

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Majumdar, S. K., A. Uppal, and P. K. Gupta. "Autofluorescence spectroscopy of oral mucosa." In BiOS '98 International Biomedical Optics Symposium, edited by Alexander V. Priezzhev, Toshimitsu Asakura, and J. D. Briers. SPIE, 1998. http://dx.doi.org/10.1117/12.311884.

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TIMOSHIN, Anton, Aleksei DOROFEEV, Kirill ERSHOV, Inna PUSTOKHINA, and Elena EMELINA. "EVALUATION OF THE EFFECTIVENESS OF TREATMENT OF THE ORAL MUCOSA WITH PHYTO-OINTMENT BASED ON PHYTOECDYSTEROIDS." In SOUTHERN BRAZILIAN JOURNAL OF CHEMISTRY 2021 INTERNATIONAL VIRTUAL CONFERENCE. DR. D. SCIENTIFIC CONSULTING, 2022. http://dx.doi.org/10.48141/sbjchem.21scon.09_abstract_timoshin.pdf.

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An indicator of the health of the human body in the state of the oral mucosa. Mechanical and chemical factors constantly influence it. At the first stage of the study, a comparative analysis of the frequency of various forms of traumatic injuries of the oral mucosa was carried out. The distribution of patients into groups was also carried out, depending on the medicinal product used. Then clinical examinations were carried out. After that, the therapy of traumatic erosive and ulcerative lesions of the oral mucosa began. The developed method for treating traumatic lesions of the oral mucosa with medicine based on phytoecdysteroids provides for the elimination of the traumatic factor, applying ointment based on phytoecdysteroids to the dried out focus twice a day. The use of phyto-ointment leads to complete repair of traumatic erosive and ulcerative lesions of the oral mucosa on average by the eighth day from the start of treatment; a similar effect with the use of "Solcoseryl dental adhesive paste" is achieved by the tenth day, and the gel "Cholisal Dental" - at a later date, which is confirmed in this study. The most significant positive effect on the level of quality of life associated with the effectiveness of treatment of traumatic erosive and ulcerative lesions of the oral mucosa in comparison with the dental “Solcoseryl dental adhesive paste” and the gel “Cholisal Dental” is exerted by phyto-ointment, where a decrease in the total points was recorded. When conducting routine examinations of patients, it is necessary to pay attention to the oral mucosa damage. Moreover, in treating traumatic injuries of the oral mucosa, it is recommended to use phytoointment, which contains phytoecdysteroids.
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Roy, Krishnendu, Ian Bottrill, Duncan R. Ingrams, Michail M. Pankratov, Elie E. Rebeiz, Peak Woo, Sadru Kabani, et al. "Diagnostic fluorescence spectroscopy of oral mucosa." In Photonics West '95, edited by R. Rox Anderson, Graham M. Watson, Rudolf W. Steiner, Douglas E. Johnson, Stanley M. Shapshay, Michail M. Pankratov, George S. Abela, et al. SPIE, 1995. http://dx.doi.org/10.1117/12.209094.

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SEVBITOV, Andrey, Aleksey DOROFEEV, Sergey MIRONOV, Samer AL-KHOURY, and Anton TIMOSHIN. "PREVENTION OF CANDIDIASIS IN PATIENTS USING REMOVABLE DENTURES." In SOUTHERN BRAZILIAN JOURNAL OF CHEMISTRY 2021 INTERNATIONAL VIRTUAL CONFERENCE. DR. D. SCIENTIFIC CONSULTING, 2022. http://dx.doi.org/10.48141/sbjchem.21scon.04_abstract_sevbitov.pdf.

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Despite innovations in orthopedic dentistry, removable dentures belong to the most popular orthopedic care category. Removable dentures are combined stimuli that affect the mucous membrane and neuro-receptor apparatus. Acrylic plastic prostheses, widely used in prosthetic dentistry, have a negative side mechanical, chemical-toxic, sensitizing, and thermal insulating effect on oral tissue and prosthetic impression area. This is often complicated by a violation of the biocenosis of the oral cavity, the growth of pathogenic microflora that releases toxins, especially an increase in the number of yeast colonies that irritate the oral mucosa and prosthetic stomatitis. It was observed 100 patients with oral candidiasis of various age groups from 45 to 65 years. Of these, 60 patients with removable plate prostheses; 40 patients with partially removable prostheses. Chronic forms of candidiasis were diagnosed in 40 patients and with exacerbation of chronic forms of candidiasis in 60 people. The number of untreated carious cavities and poor hygienic condition of the oral cavity directly affects the severity of candidiasis. Acute forms of candidiasis were observed mainly in patients with high DMF and PMA indices. The severity of candidiasis depends on the degree and duration of wearing dentures and hygienic conditions - the most severe forms of invasive candidiasis were observed in the presence of removable plate prostheses, the complete absence of teeth, and the use of a prosthesis for more than 10-15 years. A combined lesion of the oral mucosa and the red border of the lips was observed mainly in patients older than 60 years. The presence of candidiasis in the oral cavity in patients with removable plate prostheses leads to a statistically significant change in the indicators of local immunity of the oral cavity: an increase in the concentration of serum IgG and IgA and the values of the coefficient of the balance of local immunity factors.
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Rubins, Uldis, Zbignevs Marcinkevics, Robert Andrianirina Muckle, Ieva Henkuzena, Andris Roze, and Andris Grabovskis. "Remote photoplethysmography for assessment of oral mucosa." In Preclinical and Clinical Optical Diagnostics, edited by J. Quincy Brown and Ton G. van Leeuwen. SPIE, 2019. http://dx.doi.org/10.1117/12.2526979.

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Behl, Isha, Hitesh Mamgain, Atul Deshmukh, Lekha Kukreja, Arti R. Hole, and C. Murali Krishna. "Raman microspectroscopic study of oral buccal mucosa." In SPIE BiOS, edited by Robert R. Alfano and Stavros G. Demos. SPIE, 2014. http://dx.doi.org/10.1117/12.2033933.

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ZHUO, SHUANGMU, JIANXIN CHEN, XINGSHAN JIANG, ZUFANG HUANG, and SHUSEN XIE. "NONLINEAR OPTICAL MICROSCOPY OF MOUSE ORAL MUCOSA." In Proceedings of the 6th International Conference on Photonics and Imaging in Biology and Medicine (PIBM 2007). WORLD SCIENTIFIC, 2008. http://dx.doi.org/10.1142/9789812832344_0040.

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de Veld, D. C. G., M. J. H. Witjes, J. L. N. Roodenburg, W. M. Star, and H. J. C. M. Sterenborg. "Optical detection of (pre-)malignant lesions of the oral mucosa: autofluorescence characteristics of healthy mucosa." In European Conference on Biomedical Optics. Washington, D.C.: Optica Publishing Group, 2001. http://dx.doi.org/10.1364/ecbo.2001.4432_196.

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Previous clinical results demonstrate the potential of in vivo autofluorescence spectroscopy for early detection of (pre-)malignant lesions of the oral mucosa. For reliable diagnosis, it is necessary to study autofluorescence spectra of healthy mucosa first. We measured excitation-emission maps in healthy subjects and subjects with a history of cancer in the head -neck region. Our results show that different anatomical locations produce distinct autofluorescence spectra. Influences of, among others, smoking and drinking habits require further investigation.
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Edward, Kert, Tuya Shilagard, Suimin Qiu, and Gracie Vargas. "Two-photon autofluorescence spectroscopy of oral mucosa tissue." In SPIE BiOS, edited by Ammasi Periasamy, Karsten König, and Peter T. C. So. SPIE, 2011. http://dx.doi.org/10.1117/12.875049.

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de Veld, Diana C. G., Max Witjes, Jan L. Roodenburg, Willem M. Star, and Hericus J. C. M. Sterenborg. "Optical detection of (pre-)malignant lesions of the oral mucosa: autofluorescence characteristics of healthy mucosa." In European Conference on Biomedical Optics, edited by Theodore G. Papazoglou and Georges A. Wagnieres. SPIE, 2001. http://dx.doi.org/10.1117/12.447135.

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Reports on the topic "Mucosa Orale"

1

Feinberg, Stephen E. Phase 2 Clinical Trial of Intraoral Grafting of Human Tissue-Engineered Oral Mucosa. Fort Belvoir, VA: Defense Technical Information Center, October 2013. http://dx.doi.org/10.21236/ada591622.

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Bimbas, E. S., and A. S. Shishmareva. Prevention of children’s dental anomalies with anomalies of the oral mucosa. Early orthodontic treatment. SIB-Expertise, December 2022. http://dx.doi.org/10.12731/er0640.15122022.

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Данный интерактивный обучающий модуль предназначен для врачей детских стоматологов, стоматологов общей практики, ортодонтов, будет полезен студентам стоматологического факультета, ординаторам. Цель данного модуля: повышение квалификации по специальности «Детская стоматология» и «Ортодонтия»; обновление знаний об этиологии и патогенезе зубочелюстных аномалий, связанных аномалиями слизистой оболочки полости рта; особенностях профилактики и раннего ортодонтического лечения детей с аномалиями слизистой оболочки полости рта; формулирование показаний (в том числе возрастных) и алгоритмов комплексного раннего ортодонтического лечения, с определением последовательности действий специалистов. Модуль содержит теоретические, практические и контролирующие материалы по профилактике и раннему ортодонтическому лечению ЗЧА у детей с аномалиями слизистой оболочки полости рта: аномалия прикрепления уздечки языка; уздечки верхней губы; нижней губы и преддверия полости рта; наличием травматического узла. Модуль позволит сформировать у обучающихся профессиональные навыки, научит объединять в единое целое разные методики профессиональной направленности; подготовит слушателей к использованию и применению полученных знаний и умений в профессиональной деятельности.
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Clements, John D. Oral Adjuvant Therapy in the Development of Immunological Protection Against Mucosal Pathogens. Fort Belvoir, VA: Defense Technical Information Center, July 1995. http://dx.doi.org/10.21236/ada302243.

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Zeng, Qingxiang, Junjiang Liu, Fanglong Wu, and Hongmei Zhou. The optimal oral biopsy site in the diagnosis of oral mucosal autoimmune bullous disorders: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, August 2020. http://dx.doi.org/10.37766/inplasy2020.8.0024.

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