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Dissertations / Theses on the topic 'MROSiC'

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Published: 4 June 2021
Last updated: 19 February 2022

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1

Kandasamy, Sasikaran, and s3003480@student rmit edu au. "Investigation of SiC Based Field Effect Sensors with Gas Sensitive Metal Oxide Layers for Hydrogen and Hydrocarbon Gas Sensing at High Temperatures." RMIT University. Electrical and Computer Engineering, 2008. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20080724.142015.

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This PhD thesis sets out to investigate novel Silicon Carbide (SiC) based field effect devices (Schottky and transistor structures), with gas sensitive layers for monitoring hydrogen and propene gases at high temperatures. The devices developed by the author were shown to exhibit sensitivities at least 1~2 orders of magnitude (voltage shift, ƒ¢V) higher than those reported in literature. Not only did the author seek to investigate the gas sensing potential of such devices, but also he set out to study, analyse and establish the gas interaction mechanism of these novel sensors. High temperature tolerant hydrogen and hydrocarbon sensors are required in numerous applications such as: aerospace, nuclear power plant, space exploration and exhaust monitoring in automobiles. Monitoring these gases in a reliable and efficient manner is of great value in these applications, not only from a safety point of view but also for economical reasons. Hence there is an absolute necessity for simple, efficient and high performance sensors not only for monitoring and leak detection but also to function as part of a safety device to prevent accidents. The proposed sensor structure of combining SiC with gas sensitive oxide layers allow them to be operated at high temperatures, making them extremely appealing for direct or in-situ monitoring applications. The microstructural analysis performed using Atomic Force Microscopy (AFM), Scanning Electron Microscopy (SEM), X-ray Photoelectron Spectroscopy (XPS) and Rutherford Backscattering Spectroscopy (RBS) provides no evidence of inter-diffusion between different layers, in spite of the sensors being annealing at 650‹ in O2, H2 and C3H6 atmospheres for approximately 50hrs. Samples in different conditions (as deposited, annealed and tested) were compared. The electrical properties of the MROSiC (current-voltage, I-V and capacitance-voltage, C-V characteristics) and MESFET (drain current-source drain voltage (ID-VSD) and transfer, (ãID-H2 concentration) characteristics) devices were measured in the presence and absence of H2 and C3H6. Several parameters such as barrier height, saturation currents, pinch-off voltages and channel conductance were determined from the electrical characteristics, and their influence on the device performance was studied. The authorfs proposed gas interaction model based on energy band diagram is well supported by the experimental data obtained.
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2

Mrozik, Christian [Verfasser]. "Konstruktion und Inbetriebnahme eines kompakten 3-He-Polarisators / Christian Mrozik." Mainz : Universitätsbibliothek Mainz, 2014. http://d-nb.info/1058160249/34.

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3

Mrosk, Julia [Verfasser]. "Hochdurchsatz- und Kandidatengensequenzierung von Erkrankungen mit erniedrigter Knochenmasse / Julia Mrosk." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2019. http://d-nb.info/117977793X/34.

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4

Mrosk, Paolina [Verfasser]. "Endometrial Scratching vor künstlicher Befruchtung : Einfluss auf Schwangerschafts- und Lebendgeburtsraten / Paolina Mrosk." Ulm : Universität Ulm, 2021. http://d-nb.info/1237750717/34.

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5

Mrozik, Dagmar [Verfasser]. "The Jesuit Science Network: A digital prosopography on Jesuit scholars in the early modern sciences / Dagmar Mrozik." Wuppertal : Universitätsbibliothek Wuppertal, 2018. http://d-nb.info/1173805397/34.

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6

Rea, Alexander David. "Fast tip-tilt correction at the MROI and beyond." Thesis, University of Cambridge, 2015. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.708940.

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7

Mross, Oliver [Verfasser]. "Bürgerbeteiligung am Rechtsetzungsprozess in der Europäischen Union. : Ein Beitrag zur Stärkung der demokratischen Legitimation? / Oliver Mross." Berlin : Duncker & Humblot, 2010. http://d-nb.info/1238363342/34.

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8

Mross, Stefan [Verfasser], and Holger [Akademischer Betreuer] Vogt. "Integrated Multi-Sensor System for Parallel In-Situ Monitoring of Biotechnological Processes / Stefan Mross ; Betreuer: Holger Vogt." Duisburg, 2016. http://d-nb.info/1118295315/34.

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9

Westerberg, Per-Anton, Åsa Tivesten, Magnus Karlsson, Dan Mellström, Orwoll Eric, Claes Ohlsson, Tobias Larsson, Torbjörn Linde, and Östen Ljunggren. "Fibroblast growth factor 23, mineral metabolism and mortality among elderly men (Swedish MrOs)." Uppsala universitet, Njurmedicin, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-188146.

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Background: Fibroblast growth factor 23 (FGF23) is the earliest marker of disturbed mineral metabolism as renal function decreases. Its serum levels are associated with mortality in dialysis patients, persons with chronic kidney disease (CKD) and prevalent cardiovascular disease (CVD), and it is associated with atherosclerosis, endothelial dysfunction and left ventricular hypertrophy in the general population. The primary aim of this study is to examine the association between FGF23 and mortality, in relation to renal function in the community. A secondary aim is to examine the association between FGF23 and CVD related death. Methods: The population-based cohort of MrOS Sweden included 3014 men (age 69-81 years). At inclusion intact FGF23, intact parathyroid hormone (PTH), 25 hydroxyl vitamin D (25D), calcium and phosphate were measured. Mortality data were collected after an average of 4.5 years follow-up. 352 deaths occurred, 132 of CVD. Association between FGF23 and mortality was analyzed in quartiles of FGF23. Kaplan-Meier curves and Log-rank test were used to examine time to events. Cox proportional hazards regression was used to examine the association between FGF23, in quartiles and as a continuous variable, with mortality. The associations were also analyzed in the sub-cohort with estimated glomerular filtration rate (eGFR) above 60 ml/min/1.73 m(2). Results: There was no association between FGF23 and all-cause mortality, Hazard ratio (HR) 95% confidence interval (CI): 1.02 (0.89-1.17). For CVD death the HR (95% CI) was 1.26 (0.99 - 1.59)/(1-SD) increase in log(10) FGF23 after adjustment for eGFR, and other confounders. In the sub-cohort with eGFR > 60 ml/min/1.73 m(2) the HR (95% CI) for CVD death was 55% (13-111)/(1-SD) increase in log(10) FGF23. Conclusions: FGF23 is not associated with mortality of all-cause in elderly community living men, but there is a weak association with CVD death, even after adjustment for eGFR and the other confounders. The association with CVD death is noticeable only in the sub-cohort with preserved renal function.
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10

Mrosek, Matthias Patrick Alexander [Verfasser], Rolf [Akademischer Betreuer] Isermann, and Ulrich [Akademischer Betreuer] Konigorski. "Model-based control of a turbocharged diesel engine with high- and low-pressure exhaust gas recirculation / Matthias Patrick Alexander Mrosek ; Rolf Isermann, Ulrich Konigorski." Darmstadt : Universitäts- und Landesbibliothek Darmstadt, 2017. http://d-nb.info/1145141935/34.

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11

Mross, Felix [Verfasser], Edward K. [Akademischer Betreuer] Geissler, and Wolfgang [Akademischer Betreuer] Oßwald. "Effekte von Elicitin auf Wachstum, Proliferation und Signaltransduktion von Tumorzellen in vitro / Felix Mross. Betreuer: Edward K. Geissler ; Wolfgang Oßwald." Regensburg : Universitätsbibliothek Regensburg, 2012. http://d-nb.info/1029602395/34.

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12

Mrosko, Maria [Verfasser], Monika [Akademischer Betreuer] Koch-Müller, Wilhelm [Akademischer Betreuer] Heinrich, and Eugen [Akademischer Betreuer] Libowitzky. "Water incorporation in wadsleyite and ringwoodite : effect on phase stability and structure / Maria Mrosko. Gutachter: Monika Koch-Müller ; Wilhelm Heinrich ; Eugen Libowitzky. Betreuer: Monika Koch-Müller." Berlin : Technische Universität Berlin, 2013. http://d-nb.info/1065665296/34.

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13

Mrosek, Monika Verfasser], and Carsten [Akademischer Betreuer] [Framme. "Kostenkalkulation und Entgeltsituation für die DRG-Gruppen C01Z, C06Z und C61Z der Jahre 2007 und 2008 an der Augenklinik der Universität Regensburg / Monika Mrosek. Betreuer: Carsten Framme." Regensburg : Universitätsbibliothek Regensburg, 2011. http://d-nb.info/1022872370/34.

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14

Carneiro, Lionel. "Détection hypothalamique de l'hyperglycémie : rôle de la dynamique mitochondriale dans la signalisation par les espèces actives de l'oxygène." Phd thesis, Université de Bourgogne, 2011. http://tel.archives-ouvertes.fr/tel-00689166.

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L'homéostasie énergétique se définit comme le maintien de l'équilibre entre les apports et les dépenses d'énergie. La régulation nerveuse de cet équilibre est principalement assurée par l'hypothalamus. Il existe dans cette structure des neurones spécialisés dont l'activité électrique est modifiée par des signaux nerveux, métaboliques et hormonaux.Nous avons travaillé sur la détection du glucose dans cette structure, qui permet l'élaboration d'une réponse adaptée en termes de prise alimentaire et de contrôle du métabolisme. Lors de cette détection, l'utilisation du glucose conduit à la formation d'Espèces Actives de l'Oxygène d'origine mitochondriale (mEAOs) par la chaîne respiratoire mitochondriale (CRM), constituant une signalisation redox indispensable aux réponses physiologiques. De récentes études in vitro (cultures de myoblastes, hépatocytes) ont par ailleurs mis en évidence le rôle de la dynamique mitochondriale, qui contrôle la morphologie des mitochondries par des mécanismes de fission et de fusion, sur la production de mEAOs induite par une hyperglycémie. Cette dernière déclenche la fission des mitochondries de façon concomitante à la production de mEAOs. En revanche, le blocage de la fission empêche la production de mEAOs lors de l'hyperglycémie dans ces cultures. Ces études suggéraient donc que la fission soit déclenchée par l'hyperglycémie et permette alors la production de mEAOs. Mon projet de thèse a consisté à déterminer l'implication de la dynamique mitochondriale dans la signalisation mEAOs lors de la détection hypothalamique du glucose. Nos résultats nous ont permis de mettre en évidence, dans un premier temps, un adressage de la protéine de fission DRP1 à la mitochondrie dans l'hypothalamus lors d'une hyperglycémie cérébrale, évènement nécessaire au déclenchement de la fragmentation des mitochondries. Cette fragmentation est confirmée en imagerie où l'analyse morphologique montre des mitochondries plus petites, plus sphériques et moins allongées que celles des témoins. Dans un deuxième temps, nous avons déterminé l'implication de cette fission mitochondriale dans la détection hypothalamique du glucose. Son importance a pu être évaluée en bloquant la fission des mitochondries par l'inhibition de l'expression de la protéine de fission DRP1 spécifiquement dans le VMH, par interférence ARN. Cette stratégie nous a permis d'obtenir une inhibition de l'expression de DRP1 de près de 80%, 72h après l'injection. Cette inhibition est localisée au VMH et a pour conséquence une élongation des mitochondries qui présente un réseau mitochondrial plus filamenteux. L'étude du phénotype des animaux a mis en évidence une hyperphagie associée à l'inhibition de la fission mitochondriale dans le VMH. Cette hyperphagie n'entraine cependant aucune modification du poids corporel. Ceci suggère une augmentation des dépenses énergétiques chez ces animaux. De plus, ils présentent une perte de sensibilité hypothalamique au glucose qui conduit à un défaut du contrôle nerveux de la sécrétion d'insuline, ainsi qu'à une perte de l'effet satiétogène du glucose lors d'un test de réalimentation. Nous montrons que cette perte de sensibilité au glucose est due à un défaut de production hypothalamique des mEAOs en réponse au glucose, production qui est nécessaire à la signalisation responsable des réponses effectrices. Ce défaut de production de mEAOs est associé à un dysfonctionnement de la CRM. L'ensemble de ce travail permet donc de montrer pour la première fois, in vivo, que la fission mitochondriale est indispensable à la production hypothalamique de mEAOs lors d'une hyperglycémie cérébrale. Cette production est nécessaire au déclenchement du contrôle nerveux permettant d'une part la sécrétion d'insuline et d'autre part le rassasiement induit par le glucose intra-hypothalamique.
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15

Mrowiec, Thomas [Verfasser]. "Isoform specificity of 14-3-3 proteins in COPII dependent ER export of membrane proteins / vorgelegt von: Thomas Mrowiec." 2009. http://d-nb.info/995031487/34.

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16

Mrosek, Eike H. [Verfasser]. "Die Analyse von Knorpelregeneraten nach autologer Chondrozytentransplantation : Morphologie von Zell- und Matrixmarkern in der experimentellen Gelenkchirurgie / vorgelegt von Eike H. Mrosek." 2002. http://d-nb.info/965147355/34.

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17

Hung, Chun-Wei, and 洪焌瑋. "Regulation of dsRNA on MDA-5-dependent induction of mROS and autophagy in grouper cells." Thesis, 2015. http://ndltd.ncl.edu.tw/handle/32852944334979960134.

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碩士
國立臺灣大學
生命科學系
103
Fish nodavirus, the causative agent of viral nervous necrosis (VNN) of cultured marine fish, is a positive-sense single-stranded RNA virus, and will produce d.s.RNA intermediate during its replication. Fish nodavirus can stimulate innate immune responses in host cells; however, it is still unknown if melanoma different-associated protein 5 (MDA-5) can act as a d.s.RNA recognition receptor and activate intracellular innate immunity in grouper as its role in mammalian cells. In this study, poly I:C was used as an analog of viral d.s.RNA intermediate, and was transfected into a grouper brain cell line cGB which is susceptible to nervous necrosis virus. The results indicated that Poly I:C transfection could stimulate the expression of MDA-5, IRF3, IRF7 and Mx genes, and significantly increased the levels of mitochondrial oxidative substance (mROS) and autophagosomes. When MDA-5 was pre-downregulated by siRNA, the levels of Mx gene expression, mROS and autophagosomes stimulated by Poly I:C transfection all significantly decreased, indicating that d.s. RNA can induce type I interferon response, mROS and autophagy through activating MDA-5 pathway. When cGB cells were pretreated with mROS enhancer rotenone and then transfected with Poly I:C, Mx gene expression level became 3 folds higher than that in only Poly I:C-transfected cells. It is thus suggested that high mROS may synergetically enhance Poly I:C-induced Mx gene expression. Rotenone alone could upregulate autophagosome level in the treated cells, revealing that increasing of mROS could stimulate the formation of autophagosomes. When cGB cells were pretreated with mROS inhibitor and then transfected with Poly I:C, the autophagosome level decreased; furthermore, when the formation of autophagosome was inhibited by 5 mM 3MA, mROS level significantly increased, suggesting that autophagosomes may remove damaged mitochondria and downregulate mROS. This is the first report to demonstrate that MDA-5 could act as a d.s.RNA recognition receptor in fish cell line, and high mROS could synergetically enhance the Poly I:C-induced type I IFN response, and autophagy exhibited negative feedback regulation of mROS.
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18

Rotterová, Johana. "Anaerobní nálevníci jako modelová skupina pro studiu biodiverzity a symbióz v anoxických prostředích." Doctoral thesis, 2020. http://www.nusl.cz/ntk/nusl-415698.

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Ciliates are also of the most extensively studied and diverse groups of unicellular eukaryotes, and yet, their anaerobic representatives have been largely neglected; in part due to culturing difficulties. Although all main ciliate lineages contain anaerobes, their diversity and evolution of anaerobiosis are especially poorly understood and just starting to gain attention. In fact, Ciliophora is an excellent model group to study adaptations to life in anoxia, since it, apart from the aerobic majority, includes free-living and endobiotic obligately anaerobic lineages, facultative anaerobes, microaerophiles, and microaerotolerant species. The diversity of Metopida, the free-living order of obligately anaerobic class Armophorea, has been partially revised and significantly broadened during the past years, including numerous redescriptions using modern methods, as well as the description of novel families Tropidoatractidae and Apometopidae, several genera, and multiple species. Oxygen plays a crucial role in ATP production via oxidative phosphorylation that takes place in the mitochondrion in most known eukaryotes. Nevertheless, anaerobic ciliates, among many other eukaryotes that have adapted to low oxygen concentrations or even its absence, have modified their mitochondria and energetic metabolism to...
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19

Berg, Julien. "Policing financier transnational : les cellules de renseignement financier au cœur de la lutte contre le financement du terrorisme." Thèse, 2018. http://hdl.handle.net/1866/22467.

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