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Author: Grafiati
Published: 14 March 2023

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1

Ardesi, Yuri, Azzurra Pulimeno, Mariagrazia Graziano, Fabrizio Riente, and Gianluca Piccinini. "Effectiveness of Molecules for Quantum Cellular Automata as Computing Devices." Journal of Low Power Electronics and Applications 8, no. 3 (July 28, 2018): 24. http://dx.doi.org/10.3390/jlpea8030024.

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Notwithstanding the increasing interest in Molecular Quantum-Dot Cellular Automata (MQCA) as emerging devices for computation, a characterization of their behavior from an electronic standpoint is not well-stated. Devices are typically analyzed with quantum physics-based approaches which are far from the electronic engineering world and make it difficult to design, simulate and fabricate molecular devices. In this work, we define new figures of merits to characterize the molecules, which are based on the post-processing of results obtained from ab initio simulations. We define the Aggregated Charge (AC), the electric-field generated at the receiver molecule (EFGR), the Vin–Vout and Vin–AC transcharacteristics (VVT and VACT), the Vout maps (VOM) and the MQCA cell working zones (CWZ). These quantities are compatible with an electronic engineering point of view and can be used to analyze the capability of molecules to propagate information. We apply and verify the methodology to three molecules already proposed in the literature for MQCA and we state to which extent these molecules can be effective for computation. The adopted methodology provides the quantitative characterization of the molecules necessary for digital designers, to design digital circuits, and for technologists, to the future fabrication of MQCA devices.
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2

Zhang, Heying, Wei Qu, Yanfei Tao, Dongmei Chen, Shuyu Xie, Lingli Huang, Zhenli Liu, Yuanhu Pan, and Zonghui Yuan. "A Convenient and Sensitive LC-MS/MS Method for Simultaneous Determination of Carbadox- and Olaquindox-Related Residues in Swine Muscle and Liver Tissues." Journal of Analytical Methods in Chemistry 2018 (June 14, 2018): 1–9. http://dx.doi.org/10.1155/2018/2834049.

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This paper presents a convenient and sensitive LC-MS/MS method for the simultaneous determination of carbadox and olaquindox residues, including desoxyolaquindox (DOLQ), desoxycarbadox (DCBX), quinoxaline-2-carboxylic acid (QCA), 3-methyl-quinoxaline-2-carboxylic acid (MQCA), and the glycine conjugates of QCA and MQCA (namely, QCA-glycine and MQCA-glycine, resp.) in swine muscle and liver tissues. Tissue samples were extracted with 2% metaphosphoric acid in 20% methanol and cleaned up by solid-phase extraction (SPE) on a mixed-mode anion-exchange column (Oasis MAX). Analysis was performed on a C18 column by detection with mass spectrometry in the multiple reaction monitoring (MRM) mode. The limits of detection (LODs) of the six analytes were determined to be 0.01 μg·kg−1 to 0.25 μg·kg−1, and the limits of quantification (LOQs) were 0.02 μg·kg−1 to 0.5 μg·kg−1. The total recoveries of the six analytes in all tissues were higher than 79.1% with the RSD% less than 9.2%. The developed method can determine the real residue level of QCA and MQCA, whether they are present in free form or as glycine conjugates in tissues, together with the carcinogenic desoxy metabolites DCBX and DOLQ with high recovery. Therefore, this method was suitable for routine analysis of residue control programmes and the residue depletion study of CBX and OLQ on swine.
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3

Tsukerblat, Boris, Andrew Palii, and Juan Modesto Clemente-Juan. "Self-trapping of charge polarized states in four-dot molecular quantum cellular automata: bi-electronic tetrameric mixed-valence species." Pure and Applied Chemistry 87, no. 3 (March 1, 2015): 271–82. http://dx.doi.org/10.1515/pac-2014-0904.

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AbstractOur interest in this article is prompted by the problem of the vibronic self-trapping of charge polarized states in the four-dot molecular quantum cellular automata (mQCA), a paradigm for nanoelectronics, in which binary information is encoded in charge configuration of the mQCA cell. We report the evaluation of the electronic states and the adiabatic potentials of mixed-valence (MV) systems in which two electrons (or holes) are shared among four sites. These systems are exemplified by the two kinds of tetra–ruthenium (2Ru(II)+ 2Ru(III)) clusters (assembled as two coupled Creutz–Taube dimers) for which molecular implementation of mQCA was proposed. The tetra–ruthenium clusters include two holes shared among four sites and correspondingly we employ the model which takes into account the electron transfer processes as well as the Coulomb repulsion in the different instant positions of localization. The vibronic self-trapping is considered within the conventional vibronic Piepho, Krausz and Schatz (PKS) model adapted to the bi-electronic MV species with the square topology. This leads to a complicated vibronic problems (21A1g + 1B1g + 1B2g + 1Eu) ⊗ (b1g + eu) and (3A2g + 3B1g + 23Eu) ⊗ (b1g + eu) for spin-singlet and spin-triplet states correspondingly. The adiabatic potentials are evaluated with account for the low lying Coulomb levels in which the antipodal sites are occupied, the case just actual for utilization in mQCA. The conditions for the vibronic localization in spin-singlet and spin-triplet states are revealed in terms of the two actual transfer pathways parameters and strength of the vibronic coupling.
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4

Zhang, Xiya, Dapeng Peng, Yuanhu Pan, Yulian Wang, Dongmei Chen, Qi Zhou, Zhenli Liu, and Zonghui Yuan. "A novel hapten and monoclonal-based enzyme-linked immunosorbent assay for 3-methyl-quinoxaline-2-carboxylic acid in edible animal tissues." Analytical Methods 7, no. 16 (2015): 6588–94. http://dx.doi.org/10.1039/c5ay01004g.

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5

Huang, Lingli, Aiguo Xiao, Shengxian Fan, Juyi Yin, Pin Chen, Dengcai Liu, Yinsheng Qiu, Yulian Wang, and Zonghui Yuan. "Development of Liquid Chromatographic Methods for Determination of Quinocetone and Its Main Metabolites in Edible Tissues of Swine and Chicken." Journal of AOAC INTERNATIONAL 88, no. 2 (March 1, 2005): 472–78. http://dx.doi.org/10.1093/jaoac/88.2.472.

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Abstract Quinocetone (QCT), a new antimicrobial growth promotant of quinoxalines, can effectively improve the growth and feed efficiency of food animals with more safety than is provided by olaquindox and carbadox. To clarify its metabolism and residue levels in animals, a liquid chromatographic method with UV-Vis detection was developed for the determination of QCT and its main metabolites, desoxyquinocetone (DQCT) and 3-methyl-quinoxaline-2-carboxylic acid (MQCA), in muscle, liver, kidney, and fat of swine and chicken. For sample pretreatment, QCT and DQCT were extracted with ethyl acetate and purified with iso-octane; after alkaline hydrolysis of the tissue, MQCA was extracted with ethyl acetate and citric acid buffer (pH 6.0), and the extract was purified over a cation-exchange column (AG MP-50 resin). Detection was at 312 and 320 nm for QCT and DQCT, respectively, and at 320 nm for MQCA. The observed limit of detection for the 3 compounds was 0.025 μg/g in various tissues. The methods were linear over the concentrations range of 0.01-0.64 μg/mL with mean recoveries of approximately 71–86% and relative standard deviations of about 4–12% at the levels of 0.05, 0.10, and 0.20 μg/g. The method is highly selective and can be applied to the determination of QCT and its main metabolites in animal tissues, which would accelerate the pharmacokinetic and residue study of QCT in food animals.
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6

Zhang, Keyu, Manman Ban, Zhanzhong Zhao, Haihong Zheng, Xiaoyang Wang, Mi Wang, Chenzhong Fei, and Feiqun Xue. "Cytotoxicity and genotoxicity of 1,4-bisdesoxyquinocetone, 3-methylquinoxaline-2-carboxylic acid (MQCA) in human hepatocytes." Research in Veterinary Science 93, no. 3 (December 2012): 1393–401. http://dx.doi.org/10.1016/j.rvsc.2012.06.012.

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7

Mohammadi, Mohammad Nabi, and Reza Sabbaghi-Nadooshan. "Introducing a novel model based on particle wave duality for energy dissipation analysis in MQCA circuits." Journal of Computational Electronics 15, no. 2 (November 25, 2015): 683–96. http://dx.doi.org/10.1007/s10825-015-0765-2.

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8

Mao, Xin, Xiaozhen Zhou, Jun He, Gongzhen Liu, Huihui Liu, Han Zhao, Pengjie Luo, Yongning Wu, and Yanshen Li. "Metabolism Profile of Mequindox in Sea Cucumbers In Vivo Using LC-HRMS." Antibiotics 11, no. 11 (November 11, 2022): 1599. http://dx.doi.org/10.3390/antibiotics11111599.

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In this work, the metabolism behavior of mequindox (MEQ) in sea cucumber in vivo was investigated using LC-HRMS. In total, nine metabolites were detected and identified as well as the precursor in sea cucumber tissues. The metabolic pathways of MEQ in sea cucumber mainly include hydrogenation reduction, deoxidation, carboxylation, deacetylation, and combinations thereof. The most predominant metabolites of MEQ in sea cucumber are 2-iso-BDMEQ and 2-iso-1-DMEQ, with deoxidation and carbonyl reduction as major metabolic pathways. In particular, this work first reported 3-methyl-2-quinoxalinecarboxylic acid (MQCA) as a metabolite of MEQ, and carboxylation is a major metabolic pathway of MEQ in sea cucumber. This work revealed that the metabolism of MEQ in marine animals is different from that in land animals. The metabolism results in this work could facilitate the accurate risk assessment of MEQ in sea cucumber and related marine foods.
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9

Liu, Huihui, Chuanbo Ren, Dianfeng Han, Hui Huang, Rongjie Zou, Huawei Zhang, Yingjiang Xu, Xianghong Gong, Xiuzhen Zhang, and Yanshen Li. "UPLC-MS/MS Method for Simultaneous Determination of Three Major Metabolites of Mequindox in Holothurian." Journal of Analytical Methods in Chemistry 2018 (2018): 1–7. http://dx.doi.org/10.1155/2018/2768047.

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This study developed an ultraperformance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method for the detection of three major metabolites of mequindox, including 3-methyl-quinoxaline-2-carboxylic acid, 1-desoxymequindox, and 1,4-bisdesoxymequindox (MQCA, 1-DMEQ, and BDMEQ), in holothurian. Target analytes were simplified with ultrasound-assisted acidolysis extracted without complicated enzymolysis steps. After that, each sample was centrifuged and purified by an Oasis MAX cartridge. Then, the processed samples were separated and monitored by UPLC-MS/MS. This developed method has been validated according to FDA criteria. At fortified levels of 2, 10, and 20 μg/kg, recoveries ranged from 82.5% to 93.5% with the intraday RSD less than 7.27% and interday RSD less than 11.8%. The limit of detection (LOD) of all the three metabolites ranged from 0.21 to 0.48 μg/kg, while the limit of quantification (LOQ) ranged from 0.79 to 1.59 μg/kg. On application to commercial samples, 14 of 20 samples were detected positive for the three target analytes, with positive rate at 70 percentage. The result indicated that this method was specific, sensitive, and suitable for the quantification and conformation of the three major metabolites of MEQ in holothurian.
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10

Manago, Takashi, Kanta Fujii, Kenji Kasahara, and Kazuyuki Nakayama. "Spin wave propagation and nonreciprocity in metallic magnonic quasi-crystals." Journal of Physics D: Applied Physics 55, no. 11 (December 20, 2021): 115005. http://dx.doi.org/10.1088/1361-6463/ac4134.

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Abstract The characteristics of spin waves (SWs) propagating in Fibonacci magnonic quasi-crystals (MQCs) were investigated in micromagnetic simulations. The SWs feel 1/3 of the characteristic Fibonacci sequence length as a period, and mini band gaps reflected by MQCs are formed. The effect of the MQC on the SW’s propagation becomes prominent above the first band gap frequency. The properties of SWs in MQCs generally depend on the propagation direction, because SWs feel different structures depending on the direction. Therefore, the nonreciprocity (NR) characteristics becomes complex. The NR characteristics change at every band gap frequency and hence across the frequency regions defined by them. In particular, some frequency regions have almost no NR, while others have enhanced NR and some have even negative NR. These characteristics seem to provide a new way to control NR.
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11

Usui, K., and K. I. Kimura. "Sensory mother cells are selected from among mitotically quiescent cluster of cells in the wing disc of Drosophila." Development 116, no. 3 (November 1, 1992): 601–10. http://dx.doi.org/10.1242/dev.116.3.601.

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The large sensory bristles on the head and thorax of Drosophila are arranged in a precise pattern. Each bristle is formed by the progeny of a sensory mother cell (SMC) which is generated in the imaginal wing disc. The proneural genes ac and sc play an important role in the correct positioning of these SMCs by conferring to reproducibly located clusters of cells the competence to become SMCs. Indirect evidence suggested that the mitotic state of a cell could also play an important role in SMC positioning. In order to analyze the relation between the formation of SMC and the mitotic activity in the developing wing disc, we used BrdU immunolabeling to monitor the mitotic activity in an enhancer-trap transformant line, A101, where the SMCs can be visualized. Our results indicate that SMCs arise from clusters of mitotically quiescent cells (MQC), and that the cell that becomes a SMC was itself arrested at the G2 stage of the cell cycle. The emergence of MQCs follows a precise temporal and spatial pattern which is not affected by the absence of the ac and/or sc genes. We propose that the reproducible emergence of MQCs could be an important factor in the formation of SMCs.
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12

CARELLI, P., M. G. CASTELLANO, F. CHIARELLO, L. CHIATTI, M. CIRILLO, C. COSMELLI, G. DIAMBRINI PALAZZI, et al. "MQC." Annals of the New York Academy of Sciences 755, no. 1 (April 1995): 845–47. http://dx.doi.org/10.1111/j.1749-6632.1995.tb39026.x.

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13

Sankar, M. Ravi, Janakarajan Ramkumar, and S. Aravindan. "Machining of Metal Matrix Composites with Minimum Quantity Cutting Fluid and Flood Cooling." Advanced Materials Research 299-300 (July 2011): 1052–55. http://dx.doi.org/10.4028/www.scientific.net/amr.299-300.1052.

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In the present work, minimum quantity cutting fluid (MQCF) technology was developed and applied for enhancing the machining performance by maintaining eco-friendly conditions. Machining experiments were carried on Al alloy/SiC metal matrix composite using cemented carbide tool with both MQCF and flood cooling. MQCF was effective in bringing down the forces, surface roughness, flank wear by ~17 %, ~5 %, ~12.5 % respectively compared to flood cooling. In MQCF, the consumption of cutting fluid is extremely low (10ml/min) compared to flood cooling (~ 400-600 ml/min). So, emission produced in MQCF are very less, which is eco-friendly.
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14

Brown, Breann L., and Rebecca Page. "Preliminary crystallographic analysis of theEscherichia coliantitoxin MqsA (YgiT/b3021) in complex withmqsRApromoter DNA." Acta Crystallographica Section F Structural Biology and Crystallization Communications 66, no. 9 (August 26, 2010): 1060–63. http://dx.doi.org/10.1107/s1744309110028617.

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TheEscherichia coliproteins MqsR and MqsA comprise a novel toxin–antitoxin (TA) system. MqsA, the antitoxin, defines a new family of antitoxins because unlike other antitoxins MqsA is structured throughout its entire sequence, binds zinc and coordinates DNAviaits C-terminal and not its N-terminal domain. In order to understand how bacterial antitoxins, and MqsA in particular, regulate transcription, the MqsA protein was cocrystallized with a 26-mer duplex DNA corresponding to the palindromic region of themqsRApromoter. The merohedrally twinned crystal belonged to space groupP41, with unit-cell parametersa= 60.99,b= 60.99,c= 148.60 Å. A complete data set was collected to a resolution of 2.1 Å. The solvent content of the crystal was consistent with the presence of two MqsA molecules bound to the duplex DNA in the asymmetric unit.
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15

Dong, Pham Quang, Tran Minh Duc, and Tran The Long. "Performance Evaluation of MQCL Hard Milling of SKD 11 Tool Steel Using MoS2 Nanofluid." Metals 9, no. 6 (June 5, 2019): 658. http://dx.doi.org/10.3390/met9060658.

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The present work shows an experimental investigation on the effect of minimum quantity cooling lubrication (MQCL) during hard milling of SKD 11 tool steel (52–60HRC). The novelty here lies on the use of MQCL technique, which comprises the cooling strategy based on the principle of Ranque-Hilsch vortex tube and MQL method. Moreover, MoS2 nanoparticles are suspended in MQCL based fluid to improve the lubricating character. The response parameters, including surface roughness, surface microstructure, and surface profile are studied. The obtained results show that MQCL using nanofluid gives out better surface quality compared to dry, MQL, and MQCL with pure fluid. Also, the different concentrations of MoS2 nanoparticles are investigated to find out the optimized value as well as the interaction effect on machined surface.
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16

Chavan, Ajay, and Vikas Sargade. "Surface Integrity of AISI 52100 Steel during Hard Turning in Different Near-Dry Environments." Advances in Materials Science and Engineering 2020 (August 24, 2020): 1–13. http://dx.doi.org/10.1155/2020/4256308.

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AISI 52100 hardened bearing steel is popular in many industrial applications due to its excellent wear resistance and high strength. Therefore, a high level of surface integrity of the same is the utmost important requirement to enhance fatigue life. Machining of hardened AISI 52100 steel is difficult because severe plastic deformation and generation of high temperature alter the surface metallurgy of the machined component and hamper the tool life. The present investigation includes a comparative analysis of surface integrity of AISI 52100 bearing steel during hard turning under different near-dry environments, namely, dry, Minimum Quantity Cooling and Lubrication (MQCL), Compressed Chilled Air by Vortex Tube (CCAVT), and Hybrid Nanofluid Minimum Quantity Cooling and Lubrication (Hybrid NF-MQCL). Soyabean (a vegetable) oil is used as cutting fluid in MQCL and base fluid in Hybrid NF-MQCL environments. To prepare hybrid nanofluid, two different nanoparticles Al2O3 and MWCNT, are used. The chilled air is generated through a vortex tube. The surface integrity of AISI 52100 steel was studied in terms of microhardness, the thickness of the white layer, surface roughness (Ra), and residual stresses. Higher cutting speed and feed show positive and negative correlation on surface integrity of AISI 52100 steel, respectively. Hybrid nanofluid MQCL exhibits the lowest surface roughness (0.34 μm), microhardness (625 Hv0.1), compressive residual stresses (−168 MPa), and thin white layer (0.9 μm) in contrast, and dry machining shows higher surface roughness, microhardness, tensile residual stress, and thick white layer. In comparison, MQCL and CCAVT are found to be intermediate. It is found that hybrid nanofluid MQCL enhances the overall performance of the machined surface as compared to other near-dry techniques.
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17

Hanany, Amihay, Matthew J. Strassler, and Alberto Zaffaroni. "Confinement and strings in MQCD." Nuclear Physics B 513, no. 1-2 (March 1998): 87–118. http://dx.doi.org/10.1016/s0550-3213(97)00651-2.

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18

Gauntlett, Jerome P., Gary W. Gibbons, and Paul K. Townsend. "Intersecting domain walls in MQCD." Physics Letters B 483, no. 1-3 (June 2000): 240–47. http://dx.doi.org/10.1016/s0370-2693(00)00582-7.

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19

Sugimoto, S. "Comments on Duality in MQCD." Progress of Theoretical Physics 100, no. 1 (July 1, 1998): 123–46. http://dx.doi.org/10.1143/ptp.100.123.

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20

Chen, Jiejiang, Shaowei Cai, Shiwei Pan, Yiyuan Wang, Qingwei Lin, Mengyu Zhao, and Minghao Yin. "NuQClq: An Effective Local Search Algorithm for Maximum Quasi-Clique Problem." Proceedings of the AAAI Conference on Artificial Intelligence 35, no. 14 (May 18, 2021): 12258–66. http://dx.doi.org/10.1609/aaai.v35i14.17455.

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The maximum quasi-clique problem (MQCP) is an important extension of maximum clique problem with wide applications. Recent heuristic MQCP algorithms can hardly solve large and hard graphs effectively. This paper develops an efficient local search algorithm named NuQClq for the MQCP, which has two main ideas. First, we propose a novel vertex selection strategy, which utilizes cumulative saturation information to be a selection criterion when the candidate vertices have equal values on the primary scoring function. Second, a variant of configuration checking named BoundedCC is designed by setting an upper bound for the threshold of forbidding strength. When the threshold value of vertex exceeds the upper bound, we reset its threshold value to increase the diversity of search process. Experiments on a broad range of classic benchmarks and sparse instances show that NuQClq significantly outperforms the state-of-the-art MQCP algorithms for most instances.
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21

Wang, Hao, Jiawang Chen, Hang Zhou, Xiaoling Le, Dongrui Ruan, Yiping Xiao, Xin Chen, and Lu Wang. "Research on Novel Multi-Way Hydraulic Quick Connector for Underwater Production System." Marine Technology Society Journal 55, no. 6 (December 30, 2021): 129–38. http://dx.doi.org/10.4031/mtsj.55.6.16.

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Abstract The underwater hydraulic connector is one of the most important components of an underwater oil production system. The equipment is mainly used to transport oil, chemical reagents, and other high-pressure fluids. We developed a novel underwater hydraulic multi-way quick connector system (MQCS) that is able to realize simultaneous, rapid, and precise plugging and unplugging of 10 underwater pipelines. It can be widely used for connection between subsea oil production equipment. The MQCS consists of a fixed plate assembly that is fixed to the oil production equipment and a free plate assembly that is connected to the pipelines on the drilling platform. This study describes the structure and working principle of the MQCS in detail. In addition, the process of the elastic collet clamping the mandrel was studied. Based on the finite element analysis software Abaqus, we investigated how the key geometric parameters of the elastic collet influence the axial force that needs to be provided by the underwater robot. A prototype was built based on the simulation results. To verify the performance of MQCS, a high-pressure chamber test was conducted. The results show that MQCS can accurately connect 10 high-pressure lines (about 69 MPa) in a high-pressure chamber and there is no pressure drop for 3 h after docking.
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22

Li, Chang He, Chao Du, Guo Yu Liu, and Yan Zhou. "Performance Evaluation of Minimum Quantity Cooling Lubrication Using CBN Grinding Wheel." Advanced Materials Research 97-101 (March 2010): 1827–31. http://dx.doi.org/10.4028/www.scientific.net/amr.97-101.1827.

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In the grinding process, conventional method of flood delivering coolant fluid by a nozzle in order to achieve chip flushing, cooling, lubrication and chemical protection of work surface. However the conventional flood supply system demands more resources for operation, maintenance, and disposal, and results in higher environmental and health problems. Therefore, there are critical needs to reduce the use of cutting fluid in grinding process, and MQCL grinding is a promising solution. MQCL grinding refers to the use of cutting fluids of only a minute amount typically of a flow rate of 10 to 100 ml/hour which is about hundreds orders of magnitude less than the amount commonly used in flood cooling condition. The evaluation of the performance of the MQCL technique in grinding consisted of analyzing the behavior of the tangential cutting force, G-ratio, Surface morphology and roughness. The results presented here are expected to lead to technological and ecological gains in the grinding process using MQCL.
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23

Maruda, W. Radoslaw, Stanislaw Legutko, and Grzegorz M. Krolczyk. "Influence of Minimum Quantity Cooling Lubrication (MQCL) on Chip Formation Zone Factors and Shearing Force in Turning AISI 1045 Steel." Applied Mechanics and Materials 657 (October 2014): 43–47. http://dx.doi.org/10.4028/www.scientific.net/amm.657.43.

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The paper presents the results of research on the effect produced by various cooling methods on the chip thickness ratio, shear angle and shearing force. Dry cutting, cooling by compressed air and the MinimumQuantityCoolingLubrication (MQCL) method when finish turning of carbon steel with different speeds of cutting and feed rates were compared. The investigations were performed in accordance with the Parameter Space Investigation method. The advantage of the MQCL is confirmed by lower values of the chip thickening ratio, shearing force and higher values of the shear angle. Depending on the cutting conditions, the efficiency of the MQCL method is 6 to 30% higher compared to dry machining.
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24

Maruda, W. Radoslaw, Stanislaw Legutko, and Grzegorz M. Krolczyk. "Effect of Minimum Quantity Cooling Lubrication (MQCL) on Chip Morphology and Surface Roughness in Turning Low Carbon Steels." Applied Mechanics and Materials 657 (October 2014): 38–42. http://dx.doi.org/10.4028/www.scientific.net/amm.657.38.

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The paper presents the results of research on the effect produced by modern cooling methods on the chip shapes and surface roughness when finish turning of ASTM A53 and AISI 1010 low carbon steels. Dry cutting, cooling by compressed air and the Minimum–Quantity–Cooling–Lubrication (MQCL) method were compared. The MQCL method is more effective for machining low carbon steel and ensures a usable chip shape and lesser surface roughness. Depending on the cutting conditions, the efficiency of the MQCL method is 10 to 30 % higher compared to dry machining. Examples of experimental investigations about reducing the use of cooling lubricant substances in turning process can be found in the open literature [1, 2].
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25

BARBÓN, J. L. F., and A. PASQUINUCCI. "A NOTE ON SOFTLY BROKEN MQCD." Modern Physics Letters A 13, no. 18 (June 14, 1998): 1453–62. http://dx.doi.org/10.1142/s0217732398001534.

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We consider generic MQCD configurations with matter described by semi-infinite D4-branes and softly broken supersymmetry. We show that the matter sector does not introduce supersymmetry breaking parameters so that the most relevant supersymmetry breaking operator at low energies is the gaugino mass term. By studying the run-away properties of these models in the decoupling limit of the adjoint matter, we argue that these softly broken MQCD configurations fail to capture the infrared physics of QCD at scales below the gaugino mass.
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26

Evans, Nick. "Quark condensates in non-supersymmetric MQCD." Nuclear Physics B 532, no. 1-2 (October 1998): 124–36. http://dx.doi.org/10.1016/s0550-3213(98)00455-6.

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27

Stark, Richard. "Automating quality assurance for MQSA compliance." Journal of Digital Imaging 11, S1 (August 1998): 219. http://dx.doi.org/10.1007/bf03168316.

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28

KARYAKIN, Rudol’f N., and Viktor G. LOSEV. "A Modified Version of the Lightning Main Stage Mathematical Model MQCV." Elektrichestvo, no. 4 (2017): 31–38. http://dx.doi.org/10.24160/0013-5380-2017-4-31-38.

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29

Tuan, Ngo Minh, Tran Minh Duc, Tran The Long, Vu Lai Hoang, and Tran Bao Ngoc. "Investigation of Machining Performance of MQL and MQCL Hard Turning Using Nano Cutting Fluids." Fluids 7, no. 5 (April 19, 2022): 143. http://dx.doi.org/10.3390/fluids7050143.

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Cutting fluids used in the metal machining industry have exerted serious impacts on the environment and human health. In addition, the very high cutting heat and forces in machining-hardened steels have been a growing concern in the metal cutting field. Hence, new, eco-friendly cooling and lubricating techniques are necessary to study and develop. Minimum quantity lubrication (MQL) and minimum quantity cooling lubrication (MQCL) using nano cutting fluids have been proven as alternative solutions for machining difficult-to cut materials while retaining an environmentally friendly characteristic. Accordingly, this paper aims to analyze and evaluate the hard turning efficiency of 90CrSi (60 ÷ 62 HRC) steel using MQL and MQCL conditions, using Al2O3 and MoS2 nano cutting fluids. The 2k-p experimental design and analysis of variance (ANOVA) were used to study the influence of input parameters including fluid type, lubrication method, nanoparticle type, nanoparticle concentration, cutting speed and feed rate on surface roughness. The obtained results showed that the machinability of CNMG120404 TM T9125 carbide tools was improved and the highest machinable hardness was increased from 35 HRC to 60 ÷ 62 HRC (rising by approximately 71.4 ÷ 77.1%) by using the nanofluid MQL and MQCL methods. Furthermore, MQCL gives better performance than MQL, and the Al2O3 nanofluid exhibits the better result in terms of surface roughness values than the MoS2 nanofluid. Feed rate displays the strongest influence on surface roughness, while fluid type, nanoparticle concentration and cutting speed show low impacts. From these results, technical guidance will be provided for further studies using Al2O3 and MoS2 nano cutting fluids for MQL and MQCL methods, as well as their application in machining practice.
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Takei, Yuma, and Takashi Ishida. "A Benchmark Dataset for Evaluating Practical Performance of Model Quality Assessment of Homology Models." Bioengineering 9, no. 3 (March 15, 2022): 118. http://dx.doi.org/10.3390/bioengineering9030118.

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Protein structure prediction is an important issue in structural bioinformatics. In this process, model quality assessment (MQA), which estimates the accuracy of the predicted structure, is also practically important. Currently, the most commonly used dataset to evaluate the performance of MQA is the critical assessment of the protein structure prediction (CASP) dataset. However, the CASP dataset does not contain enough targets with high-quality models, and thus cannot sufficiently evaluate the MQA performance in practical use. Additionally, most application studies employ homology modeling because of its reliability. However, the CASP dataset includes models generated by de novo methods, which may lead to the mis-estimation of MQA performance. In this study, we created new benchmark datasets, named a homology models dataset for model quality assessment (HMDM), that contain targets with high-quality models derived using homology modeling. We then benchmarked the performance of the MQA methods using the new datasets and compared their performance to that of the classical selection based on the sequence identity of the template proteins. The results showed that model selection by the latest MQA methods using deep learning is better than selection by template sequence identity and classical statistical potentials. Using HMDM, it is possible to verify the MQA performance for high-accuracy homology models.
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Gu, Jinwei, Manzhan Gu, and Xingsheng Gu. "A Mutualism Quantum Genetic Algorithm to Optimize the Flow Shop Scheduling with Pickup and Delivery Considerations." Mathematical Problems in Engineering 2015 (2015): 1–17. http://dx.doi.org/10.1155/2015/387082.

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A mutualism quantum genetic algorithm (MQGA) is proposed for an integrated supply chain scheduling with the materials pickup, flow shop scheduling, and the finished products delivery. The objective is to minimize the makespan, that is, the arrival time of the last finished product to the customer. In MQGA, a new symbiosis strategy named mutualism is proposed to adjust the size of each population dynamically by regarding the mutual influence relation of the two subpopulations. A hybridQ-bit coding method and a local speeding-up method are designed to increase the diversity of genes, and a checking routine is carried out to ensure the feasibility of each solution; that is, the total physical space of each delivery batch could not exceed the capacity of the vehicle. Compared with the modified genetic algorithm (MGA) and the quantum-inspired genetic algorithm (QGA), the effectiveness and efficiency of the MQGA are validated by numerical experiments.
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Tatar, Radu, and Ben Wetenhall. "Metastable vacua, geometrical engineering and MQCD transitions." Journal of High Energy Physics 2007, no. 02 (February 7, 2007): 020. http://dx.doi.org/10.1088/1126-6708/2007/02/020.

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Ohta, Kazutoshi, and Ta-Sheng Tai. "Extended MQCD and SUSY/non-SUSY duality." Journal of High Energy Physics 2008, no. 09 (September 5, 2008): 033. http://dx.doi.org/10.1088/1126-6708/2008/09/033.

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34

Barbón, J. L. F., and A. Pasquinucci. "Softly broken MQCD and the theta angle." Physics Letters B 421, no. 1-4 (March 1998): 131–38. http://dx.doi.org/10.1016/s0370-2693(97)01587-6.

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Kinar, Y., E. Schreiber, and J. Sonnenschein. "Precision“measurement” of the potential in MQCD." Nuclear Physics B 544, no. 3 (April 1999): 633–49. http://dx.doi.org/10.1016/s0550-3213(99)00067-x.

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36

Gorsky, A. "On a Banks-Casher relation in MQCD." Journal of Experimental and Theoretical Physics Letters 69, no. 1 (January 1999): 1–6. http://dx.doi.org/10.1134/1.567974.

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37

Wu, Shenghong, Li Yu, and Chenlei Zhao. "Effect of Cooling Parameters on Cutting Vibration of Milling GH4169." Academic Journal of Science and Technology 3, no. 3 (November 21, 2022): 171–74. http://dx.doi.org/10.54097/ajst.v3i3.2931.

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Nickel base superalloy is a typical difficult to machine material. With the development of social demand, more and more attention has been paid to the research of green manufacturing technology. Reducing the emission of cutting fluid is of great significance to achieve green manufacturing. Low temperature quantity cooling (MQCL) is a kind of green manufacturing technology. In this paper, the experiments of milling superalloy GH4169 under MQCL were carried out to study the influence of cooling parameters on cutting vibration and its mechanism.
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Dong, Pham Quang, Tran Minh Duc, Ngo Minh Tuan, Tran The Long, Dang Van Thanh, and Nguyen Van Truong. "Improvement in the Hard Milling of AISI D2 Steel under the MQCL Condition Using Emulsion-Dispersed MoS2 Nanosheets." Lubricants 8, no. 6 (June 5, 2020): 62. http://dx.doi.org/10.3390/lubricants8060062.

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The present work shows the process for MoS2 nanosheet production by liquid N2-queched bulk, a novel method having highly efficient, green, and facile operation. The produced MoS2 nanoparticles are suspended in minimum quantity cooling lubrication (MQCL)-based fluid to form nanofluid used for the hard milling of AISI D2 steel. The study aims to improve the hard-milling performance assisted by the MQCL technique using MoS2 nanofluid. ANOVA analysis is used to evaluate the effects of three input machining variables, including nanoparticle concentration, cutting speed, and material hardness on cutting forces. The results indicate that the better cooling effect from the principle of the Ranque–Hilsch vortex tube of the MQCL device combined with the better lubricating performance from MoS2 nanofluid brings out the sustainable alternative solution for machining difficult-to-cut material. Moreover, the experimental results provide the technical guides for the selection of proper values of nanoparticle concentration and cutting speed while ensuring the technological, economic, and environmental characteristics.
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Mutabazi, Emmanuel, Jianjun Ni, Guangyi Tang, and Weidong Cao. "A Review on Medical Textual Question Answering Systems Based on Deep Learning Approaches." Applied Sciences 11, no. 12 (June 11, 2021): 5456. http://dx.doi.org/10.3390/app11125456.

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The advent of Question Answering Systems (QASs) has been envisaged as a promising solution and an efficient approach for retrieving significant information over the Internet. A considerable amount of research work has focused on open domain QASs based on deep learning techniques due to the availability of data sources. However, the medical domain receives less attention due to the shortage of medical datasets. Although Electronic Health Records (EHRs) are empowering the field of Medical Question-Answering (MQA) by providing medical information to answer user questions, the gap is still large in the medical domain, especially for textual-based sources. Therefore, in this study, the medical textual question-answering systems based on deep learning approaches were reviewed, and recent architectures of MQA systems were thoroughly explored. Furthermore, an in-depth analysis of deep learning approaches used in different MQA system tasks was provided. Finally, the different critical challenges posed by MQA systems were highlighted, and recommendations to effectively address them in forthcoming MQA systems were given out.
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Song, Yujie, Yuerong Xu, Yingying Liu, Jie Gao, Lele Feng, Yuxi Zhang, Lei Shi, et al. "Mitochondrial Quality Control in the Maintenance of Cardiovascular Homeostasis: The Roles and Interregulation of UPS, Mitochondrial Dynamics and Mitophagy." Oxidative Medicine and Cellular Longevity 2021 (November 11, 2021): 1–12. http://dx.doi.org/10.1155/2021/3960773.

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Maintenance of normal function of mitochondria is vital to the fate and health of cardiomyocytes. Mitochondrial quality control (MQC) mechanisms are essential in governing mitochondrial integrity and function. The ubiquitin-proteasome system (UPS), mitochondrial dynamics, and mitophagy are three major components of MQC. With the progress of research, our understanding of MQC mechanisms continues to deepen. Gradually, we realize that the three MQC mechanisms are not independent of each other. To the contrary, there are crosstalk among the mechanisms, which can make them interact with each other and cooperate well, forming a triangle interplay. Briefly, the UPS system can regulate the level of mitochondrial dynamic proteins and mitophagy receptors. In the process of Parkin-dependent mitophagy, the UPS is also widely activated, performing critical roles. Mitochondrial dynamics have a profound influence on mitophagy. In this review, we provide new processes of the three major MQC mechanisms in the background of cardiomyocytes and delve into the relationship between them.
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Xu, Chao, Jinchuan Ke, Xiaojun Zhao, and Xiaofang Zhao. "Multiscale Quantile Correlation Coefficient: Measuring Tail Dependence of Financial Time Series." Sustainability 12, no. 12 (June 16, 2020): 4908. http://dx.doi.org/10.3390/su12124908.

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In the context of the frequent occurrence of extreme events, measuring the tail dependence of financial time series is essential for maintaining the sustainable development of financial markets. In this paper, a multiscale quantile correlation coefficient (MQCC) is proposed to measure the tail dependence of financial time series. The new MQCC method consists of two parts: the multiscale analysis and the correlation analysis. In the multiscale analysis, the coarse graining approach is used to study the financial time series on multiple temporal scales. In the correlation analysis, the quantile correlation coefficient is applied to quantify the correlation strength of different data quantiles, especially regarding the difference and the symmetry of tails. One reason to adopt this method is that the conditional distribution of the explanatory variables can be characterized by the quantile regression, rather than simply by the conditional expectation analysis in the traditional regression. By applying the MQCC method in the financial markets of different regions, many interesting results can be obtained. It is worth noting that there are significant differences in tail dependence between different types of financial markets.
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Maruda, Radoslaw W., Stanislaw Legutko, Grzegorz M. Krolczyk, and Krzysztof Adamczuk. "The Effect of EP/AW Additives in Emulsion Mist on the Geometric Structure of the Machined Surface during Carbon Steel C45 Turning." Applied Mechanics and Materials 809-810 (November 2015): 15–20. http://dx.doi.org/10.4028/www.scientific.net/amm.809-810.15.

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One of the problems of metal alloys machining in view of the environment protection is the use of cooling lubricants. From this viewpoint, it is preferred to limit the use or completely eliminate them from the cutting process. The solution may be the method of Minimum Quantity Cooling Lubrication (MQCL). The results of the machined surface roughness measurements of carbon steel C45 after turning when: machining for dry cutting, using cooling method MQCL and using MQCL with additives EP/AW have been presented. One used two anti-wear and antiseizure additives based on phosphate ester. Experimental studies have been planned according to the Parameter Space Investigation method. The application of EP/AW additives entered in the emulsion determined the ranges of cutting parameters at which lower values of selected roughness parameters were obtained in comparison with dry cutting. The lowest values of Ra and Rz parameter for variables of cutting parameters and creating emulsion mist within their whole range were obtained for cooling with pure emulsion mist based on boric acid and amine compound.
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43

Pervaiz, Salman, Naveed Ahmad, Kashif Ishfaq, Sarmad Khan, Ibrahim Deiab, and Sathish Kannan. "Implementation of Sustainable Vegetable-Oil-Based Minimum Quantity Cooling Lubrication (MQCL) Machining of Titanium Alloy with Coated Tools." Lubricants 10, no. 10 (September 24, 2022): 235. http://dx.doi.org/10.3390/lubricants10100235.

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The lubrication capacity and penetration ability of the minimum quantity cooling lubrication-based strategy is linked with lubrication specific parameters (oil flow rates and air pressure), cutting conditions, and chip formation. It points out the complex selection involved in the MQCL-assisted strategy to attain optimal machining performance. Lubrication during metal cutting operations is a complex phenomenon, as it is a strong function of the cutting conditions. In addition, it also depends on the physical properties of the lubricant and chemical interactions. Minimum Quantity Lubrication (MQL) has been criticized due to the absence of cooling parts; MQCL is a modified version where a cooling part in the form of sub-zero temperatures is provided. The aim of this paper was to investigate the influence of different lubrication flow parameters under minimum quantity cooling lubrication (MQCL) when machining aeronautic titanium alloy (Ti6Al4V) using Titanium Aluminum Nitride – Physical Vapor Deposition (TiAlN-PVD) coated cutting inserts. The machining experiments on the MQCL system were performed with different levels of oil flow rates (70, 90, and 100 mL/h) and the performance was compared with the conventional dry cutting and flood cooling settings. A generic trend was observed that increasing the oil flow rate from 70—mL/h to 100 h/h improved the surface finish and reduced thermal softening at a low feed of 0.1 mm/rev. The results revealed that many tool-wear mechanisms such as adhesion, micro-abrasion, edge chipping, notch wear, built-up edge (BUE), and built-up layer (BUL) existed.
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Sligar, James, Danielle A. DeBruin, Nicholas J. Saner, Ashleigh M. Philp, and Andrew Philp. "The importance of mitochondrial quality control for maintaining skeletal muscle function across health span." American Journal of Physiology-Cell Physiology 322, no. 3 (March 1, 2022): C461—C467. http://dx.doi.org/10.1152/ajpcell.00388.2021.

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As the principal energy-producing organelles of the cell, mitochondria support numerous biological processes related to metabolism, growth, and regeneration in skeletal muscle. Deterioration in skeletal muscle functional capacity with age is thought to be driven in part by a reduction in skeletal muscle oxidative capacity and reduced fatigue resistance. Underlying this maladaptive response is the development of mitochondrial dysfunction caused by alterations in mitochondrial quality control (MQC), a term encompassing processes of mitochondrial synthesis (biogenesis), remodeling (dynamics), and degradation (mitophagy). Knowledge regarding the role and regulation of MQC in skeletal muscle and the influence of aging in this process has rapidly advanced in the past decade. Given the emerging link between aging and MQC, therapeutic approaches to manipulate MQC to prevent mitochondrial dysfunction during aging hold tremendous therapeutic potential.
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45

Dasgupta, Keshav, Kyungho Oh, and Radu Tatar. "Geometric transition, large N dualities and MQCD dynamics." Nuclear Physics B 610, no. 1-2 (September 2001): 331–46. http://dx.doi.org/10.1016/s0550-3213(01)00296-6.

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46

Fernández, Román, María Calero, Yolanda Jiménez, and Antonio Arnau. "A Real-Time Method for Improving Stability of Monolithic Quartz Crystal Microbalance Operating under Harsh Environmental Conditions." Sensors 21, no. 12 (June 17, 2021): 4166. http://dx.doi.org/10.3390/s21124166.

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Monolithic quartz crystal microbalance (MQCM) has recently emerged as a very promising technology suitable for biosensing applications. These devices consist of an array of miniaturized QCM sensors integrated within the same quartz substrate capable of detecting multiple target analytes simultaneously. Their relevant benefits include high throughput, low cost per sensor unit, low sample/reagent consumption and fast sensing response. Despite the great potential of MQCM, unwanted environmental factors (e.g., temperature, humidity, vibrations, or pressure) and perturbations intrinsic to the sensor setup (e.g., mechanical stress exerted by the measurement cell or electronic noise of the characterization system) can affect sensor stability, masking the signal of interest and degrading the limit of detection (LoD). Here, we present a method based on the discrete wavelet transform (DWT) to improve the stability of the resonance frequency and dissipation signals in real time. The method takes advantage of the similarity among the noise patterns of the resonators integrated in an MQCM device to mitigate disturbing factors that impact on sensor response. Performance of the method is validated by studying the adsorption of proteins (neutravidin and biotinylated albumin) under external controlled factors (temperature and pressure/flow rate) that simulate unwanted disturbances.
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47

Barari, Nader, Seyed Ali Niknam, and Hedayeh Mehmanparast. "Tool wear morphology and life under various lubrication modes in turning stainless steel 316L." Transactions of the Canadian Society for Mechanical Engineering 44, no. 3 (September 1, 2020): 352–61. http://dx.doi.org/10.1139/tcsme-2019-0051.

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One of the most important industrial demands is to improve the machinability of hard steels. Among hard steels, 316L stainless steel has significant mechanical and thermal properties recommended for many industrial applications and products, including aero-engines and gas turbines. Similar to many other hard-to-cut materials, the machining of 316L stainless steel requires an adequate selection of cutting parameters and lubrication modes. Limited studies have been found in this regard. In the present study, turning tests were conducted on 316L steel and the tool wear magnitude and morphology were assessed under four lubrication modes. Furthermore, to improve machining performance, a minimum quantity lubrication (MQL) system was used and the obtained results under this lubrication mode were compared to three other types of lubrication modes, including dry, wet, and MQCL. The composition of the adhered material on the cutting tools shows that in all lubrication modes, built-up edge (BUE) occurred. Furthermore, the use of high pressure-lubricated machining (MQCL) led to longer tool life as compared to the other three lubrication modes used. In fact, double the tool life was recorded for the cutting tools used under the MQCL mode.
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48

Picca, Anna, Riccardo Calvani, Hélio José Coelho-Junior, Francesco Landi, Roberto Bernabei, and Emanuele Marzetti. "Inter-Organelle Membrane Contact Sites and Mitochondrial Quality Control during Aging: A Geroscience View." Cells 9, no. 3 (March 3, 2020): 598. http://dx.doi.org/10.3390/cells9030598.

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Mitochondrial dysfunction and failing mitochondrial quality control (MQC) are major determinants of aging. Far from being standalone organelles, mitochondria are intricately related with cellular other compartments, including lysosomes. The intimate relationship between mitochondria and lysosomes is reflected by the fact that lysosomal degradation of dysfunctional mitochondria is the final step of mitophagy. Inter-organelle membrane contact sites also allow bidirectional communication between mitochondria and lysosomes as part of nondegradative pathways. This interaction establishes a functional unit that regulates metabolic signaling, mitochondrial dynamics, and, hence, MQC. Contacts of mitochondria with the endoplasmic reticulum (ER) have also been described. ER-mitochondrial interactions are relevant to Ca2+ homeostasis, transfer of phospholipid precursors to mitochondria, and integration of apoptotic signaling. Many proteins involved in mitochondrial contact sites with other organelles also participate to degradative MQC pathways. Hence, a comprehensive assessment of mitochondrial dysfunction during aging requires a thorough evaluation of degradative and nondegradative inter-organelle pathways. Here, we present a geroscience overview on (1) degradative MQC pathways, (2) nondegradative processes involving inter-organelle tethering, (3) age-related changes in inter-organelle degradative and nondegradative pathways, and (4) relevance of MQC failure to inflammaging and age-related conditions, with a focus on Parkinson’s disease as a prototypical geroscience condition.
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Picca, Anna, Flora Guerra, Riccardo Calvani, Hélio José Coelho-Junior, Maurizio Bossola, Francesco Landi, Roberto Bernabei, Cecilia Bucci, and Emanuele Marzetti. "Generation and Release of Mitochondrial-Derived Vesicles in Health, Aging and Disease." Journal of Clinical Medicine 9, no. 5 (May 12, 2020): 1440. http://dx.doi.org/10.3390/jcm9051440.

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Mitochondria are intracellular organelles involved in a myriad of activities. To safeguard their vital functions, mitochondrial quality control (MQC) systems are in place to support organelle plasticity as well as physical and functional connections with other cellular compartments. In particular, mitochondrial interactions with the endosomal compartment support the shuttle of ions and metabolites across organelles, while those with lysosomes ensure the recycling of obsolete materials. The extrusion of mitochondrial components via the generation and release of mitochondrial-derived vesicles (MDVs) has recently been described. MDV trafficking is now included among MQC pathways, possibly operating via mitochondrial–lysosomal contacts. Since mitochondrial dysfunction is acknowledged as a hallmark of aging and a major pathogenic factor of multiple age-associated conditions, the analysis of MDVs and, more generally, of extracellular vesicles (EVs) is recognized as a valuable research tool. The dissection of EV trafficking may help unravel new pathophysiological pathways of aging and diseases as well as novel biomarkers to be used in research and clinical settings. Here, we discuss (1) MQC pathways with a focus on mitophagy and MDV generation; (2) changes of MQC pathways during aging and their contribution to inflamm-aging and progeroid conditions; and (3) the relevance of MQC failure to several disorders, including neurodegenerative conditions (i.e., Parkinson’s disease, Alzheimer’s disease) and cardiovascular disease.
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Li, Yukun, Rong Lin, Xiaodong Peng, Xuesi Wang, Xinmeng Liu, Linling Li, Rong Bai, et al. "The Role of Mitochondrial Quality Control in Anthracycline-Induced Cardiotoxicity: From Bench to Bedside." Oxidative Medicine and Cellular Longevity 2022 (September 21, 2022): 1–22. http://dx.doi.org/10.1155/2022/3659278.

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Cardiotoxicity is the major side effect of anthracyclines (doxorubicin, daunorubicin, epirubicin, and idarubicin), though being the most commonly used chemotherapy drugs and the mainstay of therapy in solid and hematological neoplasms. Advances in the field of cardio-oncology have expanded our understanding of the molecular mechanisms underlying anthracycline-induced cardiotoxicity (AIC). AIC has a complex pathogenesis that includes a variety of aspects such as oxidative stress, autophagy, and inflammation. Emerging evidence has strongly suggested that the loss of mitochondrial quality control (MQC) plays an important role in the progression of AIC. Mitochondria are vital organelles in the cardiomyocytes that serve as the key regulators of reactive oxygen species (ROS) production, energy metabolism, cell death, and calcium buffering. However, as mitochondria are susceptible to damage, the MQC system, including mitochondrial dynamics (fusion/fission), mitophagy, mitochondrial biogenesis, and mitochondrial protein quality control, appears to be crucial in maintaining mitochondrial homeostasis. In this review, we summarize current evidence on the role of MQC in the pathogenesis of AIC and highlight the therapeutic potential of restoring the cardiomyocyte MQC system in the prevention and intervention of AIC.
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