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Books on the topic 'Motoer Neuron Disease – Therapy'

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Author: Grafiati

Published: 4 June 2021

Last updated: 1 February 2022

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1

Motor neuron diseases: Causes, classification, and treatments. Hauppauge, N.Y: Nova Science Publishers, 2011.

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2

Spasticity: Diagnosis and management. New York: Demos Medical Pub., 2011.

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3

Rutherford, Kunel, and John L. R. Forsythe. Motor Neuron Disease. Saunders Ltd., 2002.

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4

W, Kuncl Ralph, ed. Motor neuron disease. London: W.B. Saunders, 2002.

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5

L, Mancini Raffaele, ed. Motor neuron disease research progress. New York: Nova Biomedical Books, 2008.

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6

J, Strong Michael, ed. Dementia and motor neuron disease. Abingdon [England]: Informa UK Ltd., 2006.

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7

(Editor), David Oliver, Gian Domenico Borasio (Editor), and Declan Walsh (Editor), eds. Palliative Care in Amyotrophic Lateral Sclerosis (Motor Neuron Disease). Oxford University Press, USA, 2000.

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8

(Editor), Michael P. Barnes, and Garth R. Johnson (Editor), eds. Upper Motor Neurone Syndrome and Spasticity: Clinical Management and Neurophysiology. Cambridge University Press, 2001.

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9

1952-, Barnes Michael P., and Johnson Garth R. 1945-, eds. Upper motor neurone syndrome and spasticity: Clinical management and neurophysiology. New York, NY: Cambridge University Press, 2001.

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10

Eisen, Andrew. Motor neurone disease. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199658602.003.0009.

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In this chapter, the following ten key events in motor neurone disease, also known as amyotrophic lateral sclerosis (ALS), are considered: the first description of ALS by Cruveilhier; discovery of the first SOD1 mutation; use of the ALSFRS (functional rating scale) for determining therapeutic trial outcomes; the contentious issue of establishing the site of onset of ALS; clinical, pathological, and molecular evidence indicating that frontotemporal dementia and ALS are closely related; demonstration that ALS bears some resemblance to the transmissible spongiform encephalopathies; use of Riluzole as the approved therapy for ALS; the major inflammatory component of ALS; a Guamanian disorder that is biochemically and ultrastructurally similar to that of Alzheimer’s disease; and awareness that the true onset of ALS is unknown but certainly precedes clinical onset by years or decades.

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11

Beresford, S. Motor Neurone Disease (Therapy in Practice). Chapman & Hall, 1995.

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12

M, Cochrane George, ed. The Management of motor neurone disease. Edinburgh: Churchill Livingstone, 1987.

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13

Shaw, Pamela. The motor neurone disorders. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198569381.003.0524.

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The motor neurone diseases are a group of disorders in which there is selective loss of function of upper and/or lower motor neurones in the motor cortex, brainstem, and spinal cord resulting in impairment in the nervous system control of voluntary movement. The term ‘motor neurone disease’, often abbreviated to ‘MND’, is used differently in different countries. In the United Kingdom it is used as an umbrella term to cover the related group of neurodegenerative disorders including amyotrophic lateral sclerosis, the commonest variant, as well as progressive muscular atrophy, primary lateral sclerosis, and progressive bulbar palsy. However, in many other countries amyotrophic lateral sclerosis, referred to as ALS, has been adopted as the umbrella term for this group of clinical variants of motor system degeneration. There is a tendency now internationally to use the ALS/MND abbreviation to cover this group of conditions. Careful diagnosis within the motor neurone diseases is essential for advising about prognosis, potential genetic implications, and for identifying those with acquired lower motor neurone syndromes who may benefit for the administration of immunomodulatory therapy.

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14

David, Oliver, Borasio Gian Domenico, and Walsh Declan, eds. Palliative care in amyotrophic lateral sclerosis (motor neurone disease). Oxford: Oxford University Press, 2000.

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15

Brashear, Allison, and Elie Elovic. Spasticity: Diagnosis and Management. Springer Publishing Company, Incorporated, 2015.

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