Academic literature on the topic 'Modification de l'ADN'
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Journal articles on the topic "Modification de l'ADN":
GANG, Minsu. "Ambivalence du néo-humain et de sa communauté : entre Les Particules Élementaires et La Possibilité d’une île de Michel Houellebecq." Societe d'Etudes Franco-Coreennes 100 (December 31, 2022): 7–34. http://dx.doi.org/10.18812/refc.2022.100.7.
GANG, Minsu. "Ambivalence du néo-humain et de sa communauté : entre Les Particules Élementaires et La Possibilité d’une île de Michel Houellebecq." Societe d'Etudes Franco-Coreennes 100 (December 31, 2022): 7–34. http://dx.doi.org/10.18812/refc.2022.100.7.
Boorstein, R., J. Cadet, LN Chiu, S. Zuo, and G. Teebor. "Réparation des modifications oxydatives de l'ADN : cas de la 5-méthylcytosine dans l'ADN." Journal de Chimie Physique 91 (1994): 984–94. http://dx.doi.org/10.1051/jcp/1994910984.
Boorstein, RJ, J. Cadet, T. Hilbert, M. Lustig, R. O'Donnell, S. Zuo, and G. Teebor. "Formation, stabilité et réparation de modifications pyrimidiniques dans l'ADN." Journal de Chimie Physique 90 (1993): 837–52. http://dx.doi.org/10.1051/jcp/1993900837.
Gouri, Adel, Mohamed Bouchareb, Aoulia Dekaken, Ahmed Aimen Bentorki, Mohamed Chefrour, Régis Guieu, and Sadek Benharkat. "Epigenetics and pathogenesis of type 2 diabetes." Batna Journal of Medical Sciences (BJMS) 2, no. 1 (June 30, 2015): 56–59. http://dx.doi.org/10.48087/bjmstf.2015.2113.
COUSTHAM, Vincent, Charlotte ANDRIEUX, Chloé CERUTTI, Anne COLLIN, Ingrid DAVID, Julie DEMARS, Guillaume DEVAILLY, et al. "Epigénétique, gènes et environnement : quelle importance pour les pratiques d’élevage et les méthodes de sélection des volailles ?" INRAE Productions Animales 36, no. 4 (December 20, 2023): 7384. http://dx.doi.org/10.20870/productions-animales.2023.36.4.7384.
MERSCH, Marjorie, Sarah-Anne DAVID, Anaïs VITORINO CARVALHO, Sylvain FOISSAC, Anne COLLIN, Frédérique PITEL, and Vincent COUSTHAM. "Apports du séquençage haut-débit sur la connaissance de l'épigénome aviaire." INRA Productions Animales 31, no. 4 (January 23, 2019): 325–36. http://dx.doi.org/10.20870/productions-animales.2018.31.4.2372.
Séguin, Armand. "Évolution des espaces fonctionnels dans la région administrative de Trois-Rivières." Cahiers de géographie du Québec 26, no. 67 (April 12, 2005): 45–63. http://dx.doi.org/10.7202/021547ar.
Baba, S. S. "Détection de l'ARN et de l'antigène du virus de la rage dans des tissus de chiens infectés naturellement au Nigeria : hybridation in situ et études immunohistochimiques." Revue d’élevage et de médecine vétérinaire des pays tropicaux 52, no. 2 (February 1, 1999): 85–91. http://dx.doi.org/10.19182/remvt.9691.
Guénet, Jean-Louis. "L'édition génomique des animaux domestiques : quels enjeux et quel avenir ?" Bulletin de l'Académie vétérinaire de France 174 (2021). http://dx.doi.org/10.3406/bavf.2021.70953.
Dissertations / Theses on the topic "Modification de l'ADN":
Rio, Pascale. "Role du polymorphisme de l'adn en cancerogenese chimique : modification de l'adn par deux derives de l'acetylaminofluorene." Orléans, 1989. http://www.theses.fr/1989ORLE2027.
Ciroussel, Françoise. "La cancerogenèse par le chlorure de vinyle : modification de l'ADN et dosimétrie moléculaire." Lyon 1, 1990. http://www.theses.fr/1990LYO10057.
Spadiliero, Barbara. "Epigenetic traits in the parasite Trypanosoma cruzi : DNA and histones modifications linked to its life cycle." Paris 6, 2009. http://www.theses.fr/2009PA066759.
BELGUISE-VALLADIER, PASCALE. "Etude de la modification de l'adn par un cancerogene, le n-2-acetylaminofluorene : etudes structurales et consequences biologiques." Strasbourg 1, 1993. http://www.theses.fr/1993STR13204.
Bougueleret, Lydie. "Contribution à l'étude des systèmes de restriction modification EcoR I et EcoR V." Paris 7, 1985. http://www.theses.fr/1985PA077010.
Fonteneau, Mathieu. "La modification de la méthylation de l'ADN régule le comportement d'auto-administration de cocaïne chez le rat : caratérisation des gènes impliqués." Thesis, Strasbourg, 2014. http://www.theses.fr/2014STRAJ059/document.
Repeated drug administration lead to pathological brain plasticity that requires modifications of gene expression through, among others, epigenetic mechanisms such DNA methylation. Here, we showed that DNA methyltransferases inhibitors such 5-aza-2’-deoxycytidine increase reinforcing properties of cocaine in an intravenous self administration paradigm without affecting the motivation of rats for the drug, nor drug seeking after withdrawal. The analysis of the methylome in the medial prefrontal cortex allowed us to identify approximatively 190000 differentially methylated genomic regions in response to cocaine treatment, in association or not with 5-aza-2’-deoxycytidine. We selected around twenty regions within promoters or body of genes known to participate in neuronal plasticity. The study of the transcription of these genes permitted for some of them to correlate the modifications of the DNA methylation with the modifications of the expression, like, for example, in the case of the gene Hdac2
Heberle, Eléa. "Etude du rôle et de la régulation de la Poly(ADP-ribose) Glycohydrolase(PARG) dans la réponse cellulaire aux dommages à l'ADN." Thesis, Strasbourg, 2017. http://www.theses.fr/2017STRAJ106.
Poly (ADP-ribosyl) ation is a post-translational modification of proteins involved in a large number of biological processes, including DNA repair. While the function and mode of action of Poly (ADP-ribose) (PAR) Polymerase 1 (PARP1), activated in response to DNA damage, is well understood, much less is known about the function and regulation the PAR degrading enzyme, Poly (ADP-ribose) glycohydrolase (PARG). In the context of this thesis project, we describe new stable U2OS lines, deficient for all PARG isoforms, allowing the inducible complementation with each of the PARG isoforms. These models allowed us to evaluate the relative contributions of the isoforms to DNA damage repair. We have identified a new cellular partner of PARG: the DNA-dependent protein kinase-dependent kinase (DNA-PK). We explore the functional interaction between these two proteins in the context of the cellular response to camptothecin (CPT), an anticancer drug that inhibits topoisomerase I and induces the simultaneous activation of PARP1 and DNA-PK
Malytska, Iuliia. "Exploring bipolar electrochemistry for the modification of unusual conducting substrates." Thesis, Bordeaux, 2018. http://www.theses.fr/2018BORD0135/document.
Bipolar electrochemistry is a phenomenon based on the polarization of conductive objects in an electric field. In contrast to conventional electrochemistry, the drop of potential in the electrolyte solution triggers the involved redox reactions. When a conductive object is positioned in an electric field present in a solution between two feeder electrodes, it is polarized and becomes a bipolar electrode. The potential difference between the electrolyte and the bipolar electrode is the driving force for reduction/oxidation reactions at the two extremities of the bipolar electrode; oxidation will occur at one end, combined simultaneously with reduction at the other end.Bipolar electrochemistry is a concept that allows generating an asymmetric reactivity at the surface of a conductive object. During the last decade, bipolar electrochemistry found many applications such as the synthesis of asymmetric micro- and nano-particles, electrodeposition, sensing, propulsion of microobjects, electroanalysis etc. The advantage of this technique is its wireless character, which allows the modification of delicate materials and also to electrochemically address many objects simultaneously.In the present thesis, the approach was applied to different semiconducting materials and biological systems. In addition, properties of substrates of different nature have been studied using bipolar electrochemistry.In this way, it was possible to create metal deposits on organic charge transfer salts in a site-specific way. The resulting hybrid metal/organic particles were tested for the asymmetric generation of photovoltage under illumination.Inorganic transition metal dichalcogenides were also used as a substrate for bipolar electrochemistry. Deposition of different metals on MoSe2 macroparticles was performed. Transition metal dichalcogenides are known for their catalytic activity with respect to hydrogen evolution reaction. Therefore, wireless hydrogen production on MoSe2 crystals and microparticles could be demonstrated by using bipolar electrochemistry. In the latter case it is possible to envision their use for electrochemical decontamination of solutions in the bulk.Finally, bipolar electrochemistry has also been used for studying the conductivity of biological molecules (DNA). The primary goal was to develop a new approach for the asymmetric modification of DNA by metal nanoparticles. Experiments were performed by using either Capillary Assisted Bipolar Electrodeposition (CABED) with the DNA molecules present in the bulk, or by immobilizing DNA as stretched entities on model surfaces for subsequent modification. Encouraging first results could be evidenced by TEM or AFM measurements
Hu, Guojian. "Hormonal and epigenetic control of pollination-dependent and pollination-independent fruit-setting in tomato." Phd thesis, Toulouse, INPT, 2017. http://oatao.univ-toulouse.fr/18575/1/HU.pdf.
El, Khoury Victoria Dufer Jean. "Etude de modifications épigénétiques corrélées à l'expression du gène MDR1 et à la texture nucléaire dans des cellules de carcinome pulmonaire H69 sensibles et résistantes à la chimiothérapie." S.n. : S.l, 2006. http://scdurca.univ-reims.fr/exl-doc/GED00000322.pdf.