Academic literature on the topic 'Moderate hearing loss'
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Journal articles on the topic "Moderate hearing loss"
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KAWANO, MICHIO. "Moderate hearing loss causing delayed detection." AUDIOLOGY JAPAN 29, no. 5 (1986): 533–34. http://dx.doi.org/10.4295/audiology.29.533.
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JOHNSON, KATE. "‘Mild to Moderate’ Hearing Loss Underappreciated." Family Practice News 38, no. 5 (March 2008): 57. http://dx.doi.org/10.1016/s0300-7073(08)70328-1.
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Dinces, Elizabeth A., and Sanjay R. Parikh. "Implantable hearing aids for moderate-to-severe hearing loss." Operative Techniques in Otolaryngology-Head and Neck Surgery 14, no. 4 (December 2003): 277–81. http://dx.doi.org/10.1053/s1043-1810(03)00060-5.
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Markova, Tatiana, Natalia Alekseeva, Maria Lalayants, Oxana Ryzhkova, Olga Shatokhina, Nailya Galeeva, Elena Bliznetz, et al. "Audiological Evidence of Frequent Hereditary Mild, Moderate and Moderate-to-Severe Hearing Loss." Journal of Personalized Medicine 12, no. 11 (November 4, 2022): 1843. http://dx.doi.org/10.3390/jpm12111843.
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Congenital and early onset bilateral sensorineural hearing loss (SNHL) is mainly caused by mutations in numerous genes. The introduction of universal newborn hearing screening (UNHS) has increased the number of infants with mild, moderate, and moderate-to-severe sensorineural hearing loss (SNHL) detected in the first year of life. We aimed to evaluate the audiological features in patients with mild, moderate, and moderate-to-severe SNHL according to genotype. Audiological and genetic data were analyzed for 251 patients and their relatives with congenital bilateral mild, moderate, and moderate-to-severe SNHL. Hearing loss severity, audiogram profile, interaural symmetry, and dynamics of hearing thresholds were analyzed. In this case, 165 patients had GJB2 gene mutations, 30 patients were identified with STRC mutations, and 16 patients had pathogenic or likely pathogenic USH2A mutations. The presence of at least one GJB2 non-truncating variant in genotype led to less severe hearing impairment. The flat and gently sloping audiogram profiles were mostly revealed in all groups. The follow-up revealed the stability of hearing thresholds. GJB2, STRC, and USH2A pathogenic variants were detected in most patients in our cohort and were congenital in most cases.
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KOTERA, KAZUOKI. "Indication of hearing aid for mild-to-moderate hearing loss." AUDIOLOGY JAPAN 29, no. 5 (1986): 551–52. http://dx.doi.org/10.4295/audiology.29.551.
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Guerra, Alexis. "Malaria Drug Could Moderate Genetic Hearing Loss." Hearing Journal 72, no. 7 (July 2019): 20. http://dx.doi.org/10.1097/01.hj.0000575364.22209.74.
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JOHNSON, KATE. "Experts Flag ‘Mild to Moderate’ Hearing Loss." Pediatric News 42, no. 3 (March 2008): 34. http://dx.doi.org/10.1016/s0031-398x(08)70133-4.
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Lofgren, Sarah, Martha Montgomery, Nathan Yueh, Alice Namudde, Joshua Rhein, Mahsa Abassi, Abdu Musubire, David Meya, and David Boulware. "Hearing Loss in Cryptococcal Meningitis Survivors." Open Forum Infectious Diseases 4, suppl_1 (2017): S306. http://dx.doi.org/10.1093/ofid/ofx163.709.
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Abstract Background Hearing loss is a known complication cryptococcal meningitis (CM); however, there is a paucity of data. We aimed to describe hearing loss in CM survivors. Methods We assessed hearing via audiometry 8 and 18 weeks after diagnosis of CM in Kampala, Uganda from 2015-2016. We measured at 0.5, 1, 2, 4 Hz. Normal hearing was defined as minimum hearing level at <25 decibels (dB), mild at 25-39, moderate hearing at 40–69, severe at 70–89, and profound hearing loss at 90+ dB. We compared clinical factors, fungal burden, and CSF parameters to evaluate for factors associated with improvement (change in hearing loss category). Results We evaluated hearing symptoms via audiogram at week 8 (n = 117) and week 18 (n = 98). At 8-weeks, 6 (5%) participants had normal hearing, 36 (31%) had mild hearing loss, 72 (62%) had moderate hearing loss, 3 (3%) had severe hearing loss and none had profound hearing loss. Of those with moderate/severe/profound loss at week 8, 63 (54%) had mixed conductive + sensorineural hearing loss, 15 (13%) had sensorineural hearing loss, and 14 (12%) had conductive hearing loss. An additional 19 (16%) had sensorineural loss but unknown air conduction, and 3 (3%) did not have sensorineural loss but unknown air conduction. We compared risk factors for hearing loss summarized in Table 1. We assessed 66 participants who had repeated audiograms at week 8 and week 18. Of those 31 (47%) had no change, 30 (45%) had improvement and 5 (8%) had worsening. Conclusion Moderate/severe hearing loss was common 8 weeks after diagnosis of CM. More than half had mixed hearing loss and 20% had conductive hearing loss which represents a higher incidence than noted in other types of meningitis. The data is complicated by advanced HIV. Further research is needed evaluating immunologic factors causes hearing impairment in those who survived CM. Disclosures All authors: No reported disclosures.
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Tasell, Dianne J. Van. "Hearing Loss, Speech, and Hearing Aids." Journal of Speech, Language, and Hearing Research 36, no. 2 (April 1993): 228–44. http://dx.doi.org/10.1044/jshr.3602.228.
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Modern hearing aids permit adjustment of a number of electroacoustic parameters, among them frequency response, saturation sound pressure level, and various aspects of compression. Relatively little is known, however, about how the electroacoustic characteristics of hearing aids affect the information-bearing properties of speech. Even less is known about how hearing aids might alleviate or exacerbate the effects of impaired hearing. This article reviews current knowledge in three areas: (a) characteristics of mild/moderate hearing loss, (b) informationbearing aspects of speech, and (c) the relation between electroacoustic characteristics of hearing aids and the speech signal. Concluding suggestions are made regarding the implications of the current data for selecting hearing-aid characteristics.
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Lister, Jennifer, Aryn Harrison Bush, Jennifer O’Brien, Laura Conover, and Nasreen Sadeq. "DOES HEARING LOSS MODERATE THE RELATIONSHIP BETWEEN COGNITION AND DEPRESSION?" Innovation in Aging 7, Supplement_1 (December 1, 2023): 753. http://dx.doi.org/10.1093/geroni/igad104.2436.
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Abstract Hearing loss, depression, and cognitive impairment are common, co-occurring conditions experienced by older adults, but the nature of the relationship among these conditions remains unclear. Both depression and hearing loss have been identified as risk factors for dementia, but for different stages of life (e.g., Singh-Manoux et al., 2017; Livingston et al., 2020). Hearing loss is described as the strongest modifiable risk factor in mid-life, and depression is second only to smoking as the strongest modifiable risk factor in late-life (Livingston et al., 2020). The association between hearing loss and depression is well documented in the literature (e.g., Lawrence et al., 2015). It is possible that hearing loss, as an earlier risk factor, moderates the relationship between depression and cognition. Therefore, as part of an ongoing longitudinal study of early indicators of cognitive decline, we examined the moderating effect of two measures of hearing (pure-tone hearing threshold average, Dichotic Sentence Identification test) on the relationship between depression (Geriatric Depression Scale) and cognition (Montreal Cognitive Assessment, Digit Symbol Substitution test) for a group of 65 older adults (mean age 74). Although none of the hearing or cognitive measures were significant predictors of depression scores on their own, there was a significant negative interaction between the Montreal Cognitive Assessment and pure-tone hearing threshold average, p = 0.048. These results may be interpreted to suggest that individuals with higher (poorer) hearing thresholds show a decrease in depression as their cognitive scores improve, whereas individuals with lower (better) hearing thresholds show the opposite pattern.
Dissertations / Theses on the topic "Moderate hearing loss"
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Gonzenbach, Stephen Albert. "The relationship between sentence recognition, hearing handicap and personality in males with mild to moderate hearing loss /." Access Digital Full Text version, 1989. http://pocketknowledge.tc.columbia.edu/home.php/bybib/10858155.
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Thesis (Ed.D.) -- Teachers College, Columbia University, 1989.Typescript; issued also on microfilm. Sponsor: Eleanor B. Morrison. Dissertation Committee: Honor O'Malley, Richard W. Matthes. Bibliography: leaves 102-107.
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Yip, Ki-chun Charis, and 葉琪蓁. "Effects of noise on speech understanding in individuals with moderate to severe hearing loss." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B44489948.
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Grobbelaar, Annerina. "Linear frequency transposition and word recognition abilities of children with moderate-to-severe sensorineural hearing loss." Diss., Pretoria : [s. n.], 2009. http://upetd.up.ac.za/thesis/available/etd-03112010-104801.
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Edmondson, Suzanne Marie. "An interpretive phenomenological analysis of the lived experiences of young people with a moderate hearing loss attending mainstream secondary school." Thesis, University of Birmingham, 2017. http://etheses.bham.ac.uk//id/eprint/7829/.
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Research indicates that children with hearing loss face a number of difficulties academically, socially and emotionally. Although there has been much research with the severe to profound deaf population there has been little research into the life experiences of children with moderate hearing loss who attend mainstream secondary schools. This research sought to address this by examining the experiences of five Year nine children with moderate hearing loss. Data was gathered through semi-structured interviews in the young person’s school setting and was analysed using Interpretative Phenomenological Analysis. Although each participant had unique experiences there seemed to be a number of common themes arising including; coping and support, social acceptance, self-concept and confidence, auditory factors and teachers and learning. This study indicates that young people with moderate hearing loss continue to face social, emotional and academic challenges. With educational psychologists regularly visiting schools there appears to be a role for them in increasing deaf awareness and checking that young people with a hearing loss are receiving the necessary support.
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Halliday, Lorna F. "Are auditory processing deficits linked to literacy problems : a comparison of specific reading disability and mild to moderate sensorineural hearing loss." Thesis, University of Oxford, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.427616.
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Mamelle, Elisabeth. "Réhabilitation des surdités de perception par des thérapies locales Hyaluronic acid liposomal gel sustains delivery of a corticoid to the inner ear Assessment of the efficacy of a local steroid rescue treatment administered 2 days after a moderate noise-induced trauma in guinea pig." Thesis, Sorbonne université, 2019. http://www.theses.fr/2019SORUS576.
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Le développement de thérapies locales pour traiter les pathologies de l’oreille interne est un domaine de recherche majeur en otologie, permettant de s’affranchir des barrières anatomiques et d’obtenir une concentration efficace de substance active dans la cochlée. Dans ce but, une formulation de gel d’acide hyaluronique contenant des liposomes encapsulant une substance active, a été développée pour être administrée par voie transtympanique. Le phosphate de dexaméthasone (anti-inflammatoire) était utilisé pour démontrer l'intérêt de cette formulation. Nous avons montré que ce gel était capable d’assurer une libération prolongée de dexaméthasone jusqu’à 30 jours dans la périlymphe de cobaye, grâce aux liposomes qui formaient des réservoirs capables de franchir la fenêtre ronde. Chez le cobaye normo-entendant implanté cochléaire, l’injection peropératoire de gel contenant du phosphate de dexaméthasone permettait une meilleure préservation de l’audition à sept jours de la chirurgie, comparé au groupe témoin, sans substance active. En revanche, lorsque le gel de phosphate de dexaméthasone était appliqué 48 h après un traumatisme sonore, aucune récupération auditive supplémentaire n'était observée par rapport à la récupération spontanée de l’audition chez le cobaye. Au total, le gel d’acide hyaluronique contenant des liposomes est un bon candidat pour traiter les pathologies de l’oreille interne avec des concentrations efficacesLocal drug delivery to the inner ear is a promising treatment to ensure a sustained release of therapeutic agents into the cochlea bypassing its anatomic barriers. A hyaluronic acid gel containing liposomes that encapsulate a therapeutic agent was designed for transtympanic injection. Anti-inflammatory dexamethasone phosphate was the encapsulated drug selected to demonstrate the interest of this formulation. Therapeutic concentrations of dexamethasone were determined in perilymph of guinea pig 30 days after the local application. Liposomes acted as reservoirs, able to cross the round window membrane. In cochlear implanted guinea pigs, with normal hearing, when the dexamethasone gel was applied immediately after the cochlear implantation, better hearing thresholds were observed compared to the control group without drug. However, after an acoustic trauma, local dexamethasone gel, administered 48 h after the trauma, failed to improve the hearing compared to the spontaneous recovery. Finally, the hyaluronic acid gel loaded with liposomes is a good candidate to reach effective concentration of drugs for inner ear therapy
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Teveny, Sarah. "Acquisition des morphèmes grammaticaux libres par des enfants atteints de surdité moyenne; Analyse multidimensionnelle." Electronic Thesis or Diss., Paris 3, 2023. http://www.theses.fr/2023PA030035.
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Lorsqu’elle apparait dans les premiers mois de l’enfant, la surdité moyenne (pertes auditives entre 40dB et 70dB) peut entrainer des difficultés dans l’acquisition du langage, notamment en ce qui concerne la phonologie et la morphologie (Briscoe et al., 2001; Norbury et al., 2001; Tuller & Delage, 2014). Cette thèse étudie les réalisations des morphèmes grammaticaux libres en position prénominale et préverbale chez ces enfants, en étudiant l’influence de facteurs pragmatiques, morphologiques et phonologiques et l’interaction entre différents niveaux de difficulté. La variabilité des résultats des enfants sourds moyens ayant été relevée auparavant (Halliday et al., 2017; Koehlinger et al., 2013; Moeller et al., 2010; Tomblin et al., 2015), une comparaison avec celle des enfants normo-entendants est proposée. Un groupe d’enfants sourds moyens de moins de 6 ans et deux groupes d’enfants normo-entendants, d’âge similaire et plus jeunes, ont été enregistrés deux fois à un an ou un an et demi d’écart, dans différentes tâches : tests de langage, narration et jeu symbolique. Les enfants sourds moyens ont des difficultés en production (vocabulaire, morphosyntaxe et phonologie) plus souvent qu’ils en ont en compréhension. Dans les deux sessions, leur inventaire phonologique est comparable à celui d’enfants normo-entendants plus jeunes, en revanche leurs schémas de transformations diffèrent. Les facteurs pragmatiques comme le statut discursif de l’expression référentielle ou le type de référence ont une influence similaire chez les enfants sourds moyens et les enfants plus jeunes. Cependant, des facteurs morphologiques, comme le genre du nom, n'ont d’influence que dans les productions des enfants sourds moyens. Pour approfondir le lien entre phonologie et morphologie, la production des phonèmes a été analysé selon le type de mot ou selon la catégorie de la forme produite. Il apparait que les formes dont la cible est un pronom ou un déterminant sont plus souvent transformées que celles dont la cible est un lexème ou un autre type de morphème prélexical. À tous les niveaux de l’analyse, la variation interindividuelle diffère de celles des enfants normo-entendants tant dans la dispersion des productions du groupe que dans son évolutionWhen moderate hearing loss (between 40dB and 70dB of loss) occurs in the first few months of a child's life, it can cause some difficulties in language acquisition, and particularly in phonology and morphology (Briscoe et al., 2001; Norbury et al., 2001; Tuller & Delage, 2014). This thesis investigates the realizations of free grammatical morphemes in prenominal and preverbal positions in those children’s productions, by examining the influence of pragmatic, morphological, and phonological factors as well as the interaction between different levels of difficulty. Variability in the performance of children with moderate hearing loss (Halliday et al., 2017; Koehlinger et al., 2013; Moeller et al., 2010; Tomblin et al., 2015) was addressed through a comparison with the variations in normal-hearing children’s productions. A group of children with moderate hearing loss under 6 years old, and two groups of normal-hearing children, one similar in age and one younger, were recorded one or one and a half years apart in different tasks: language tests, narrative and symbolic play. The children with moderate hearing loss had difficulties in production (vocabulary, morphosyntax, and phonology) more often than they had in comprehension. In both sessions, their phonological inventory was comparable to the younger normal-hearing children one, but their transformation patterns differed. Pragmatic factors such as the discursive status of the referential expression or the type of reference had a similar impact on the average child with moderate hearing loss and the younger children. However, morphological factors such as the noun gender impacted only the production of children with moderate hearing loss. To further investigate the link between phonology and morphology, phonemes production was analysed according to the category of the produced form. It appears that, when pronouns or determiners were targeted, the forms were more often transformed than when the target was another type of prelexical morpheme. At all levels of analysis, the inter-individual variation differed from that of normal hearing children, both in its spread and in evolution
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Johnson, Earl E. "An Initial-Fit Comparison of Two Generic Hearing Aid Prescriptive Methods (NAL-NL2 and CAM2) to Individuals Having Mild to Moderately Severe High-Frequency Hearing Loss." Digital Commons @ East Tennessee State University, 2013. https://dc.etsu.edu/etsu-works/1701.
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Background: Johnson and Dillon (2011) provided a model-based comparison of current generic hearing aid prescriptive methods for adults with hearing loss based on the attributes of speech intelligibility, loudness, and bandwidth. Purpose: This study compared the National Acoustic Laboratories-Non-linear 2 (NAL-NL2) and Cambridge Method for Loudness Equalization 2-High-Frequency (CAM2) prescriptive methods using adult participants with less high-frequency hearing loss than Johnson and Dillon (2011). Of study interest was quantification of prescribed audibility, speech intelligibility, and loudness. The preferences of participants for either NAL-NL2 or CAM2 and preferred deviations from prescribed settings are also reported.
Research Design: Using a single-blind, counter-balanced, randomized design, preference judgments for the prescriptive methods with regard to sound quality of speech and music stimuli were obtained. Preferred gain adjustments from the prescription within the 4-10 kHz frequency range were also obtained from each participant. Speech intelligibility and loudness model calculations were completed on the prescribed and adjusted amplification.
Study Sample: Fourteen male Veterans, whose average age was 65 yr and whose hearing sensitivity averaged normal to borderline normal through 1000 Hz sloping to a moderately severe sensorineural loss, served as participants.
Data Collection and Analysis: Following a brief listening time (∼10 min), typical of an initial fitting visit, the participants made paired comparison of sound quality between the NAL-NL2 and CAM2 prescriptive settings. Participants were also asked to modify each prescription in the range of 4-10 kHz using an overall gain control and make subsequent comparisons of sound quality preference between prescriptive and adjusted settings. Participant preferences were examined with respect to quantitative analysis of loudness modeling, speech intelligibility modeling, and measured high-frequency bandwidth audibility.
Results: Consistent with the lack of difference in predicted speech intelligibility between the two prescriptions, sound quality preferences on the basis of clarity were split across participants while some participants did not have a discernable preference. Considering sound quality judgments of pleasantness, the majority of participants preferred the sound quality of the NAL-NL2 (8 of 14) prescription instead of the CAM2 prescription (2 of 14). Four of the 14 participants showed no preference on the basis of pleasantness for either prescription. Individual subject preferences were supported by loudness modeling that indicated NAL-NL2 was the softer of the two prescriptions and CAM2 was the louder. CAM2 did provide more audibility to the higher frequencies (5-8 kHz) than NAL-NL2. Participants turned the 4-10 kHz gain recommendation of CAM2 lower, on average, by a significant amount of 4 dB when making adjustments while no significant adjustment was made to the initial NAL-NL2 recommendation.
Conclusions: NAL-NL2 prescribed gains were more often preferred at the initial fitting by the majority of participating veterans. For those patients with preference for a louder fitting than NAL-NL2, CAM2 is a good alternative. When the participant adjustment from the prescription between 4 and 10 kHz exceeded 4 dB from either NAL-NL2 (2 of 14) or CAM2 (11 of 14), the participants demonstrated a later preference for that adjustment 69% of the time. These findings are viewed as limited evidence that some individuals may have a preference for high-frequency gain that differs from the starting prescription.
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Goldstein, Richard Marc. "Mild to moderate hearing loss in older adults how normal hearing spouses cope with their partners' acquired hearing loss /." 1991. http://catalog.hathitrust.org/api/volumes/oclc/25378818.html.
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Thesis (Ph. D.)--University of Wisconsin--Madison, 1991.Typescript. eContent provider-neutral record in process. Description based on print version record. Includes bibliographical references (leaves 185-195).
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"The metaphor in construction of comprehension by child with moderate hearing loss." Tese, MAXWELL, 2004. http://www.maxwell.lambda.ele.puc-rio.br/cgi-bin/db2www/PRG_0991.D2W/SHOW?Cont=5759:pt&Mat=&Sys=&Nr=&Fun=&CdLinPrg=pt.
Full textBooks on the topic "Moderate hearing loss"
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Luxon, Linda. Disorders of hearing. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198569381.003.0301.
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Hearing loss is the commonest sensory disability worldwide, and the World Health Organisation has estimated that 278 million people suffer a moderate to profound hearing loss in both ears, with 80 per cent of deaf and hearing-impaired people living in low- and middle-income countries (WHO 2006). Tinnitus affects approximately 10 per cent of developed populations (Coles 1984) and of these, 5 per cent find the symptom troublesome and seek help (Davis 1995). Tinnitus and hearing loss are primary symptoms of disordered cochlear function, but may also present as a result of central auditory pathology with normal cochlear function. Pathology affecting the central auditory pathways characteristically presents as difficulty hearing in conditions of poor signal-to-noise ratio, for example, in a classroom in the presence of background noise, listening to transmitted sound, for example on the telephone or on a television, and sound localization. As a consequence of multiple relays and bilateral representation above the level of the cochlear nuclei, central auditory dysfunction does not present with hearing loss. Hearing loss and/or tinnitus, with or without associated vestibular abnormalities, will most commonly be the result of otological pathology. However, importantly for the neurologist cochlear, VIII nerve, or central auditory dysfunction may be part of the clinical presentation of a neurological disorder.
Book chapters on the topic "Moderate hearing loss"
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Polo, Edoardo Maria, Maximiliano Mollura, Riccardo Barbieri, and Alessia Paglialonga. "Multivariate Classification of Mild and Moderate Hearing Loss Using a Speech-in-Noise Test for Hearing Screening at a Distance." In Lecture Notes of the Institute for Computer Sciences, Social Informatics and Telecommunications Engineering, 81–92. Cham: Springer Nature Switzerland, 2023. http://dx.doi.org/10.1007/978-3-031-28663-6_7.
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Naz, Sadaf. "Genetics of Nonsyndromic Recessively Inherited Moderate to Severe and Progressive Deafness in Humans." In Hearing Loss. InTech, 2012. http://dx.doi.org/10.5772/31808.
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Brice, Alejandro. "Noise Induced Hearing Loss: A Case Study from a Speech-Language Pathologist’s Perspective." In Hearing Loss - From Multidisciplinary Teamwork to Public Health. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96332.
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Hearing loss is very common in the United States and the most widespread disability in the U.S. Hearing loss is the third most chronic health condition in the U.S. Noise induced hearing loss (NIHL) results from damaging external noise. This injury leads to temporarily or permanently affecting sensitive inner ear structures (e.g., cochlea, organ of Corti, and hair cells). NIHL can result from a single high-level noise exposure or repeated exposures to excessively loud noises [i.e., typically 85 dBA or greater, (A weighted decibel)]. Damage to the inner ear can also result from aging (i.e., presbycusis). This case study documents the hearing loss of an otherwise healthy 21-year-old, male individual and his progressive moderate-to-severe sensorineural hearing loss over a period of 41 years. His history will be reported along with his perspective as a speech-language pathologist and speech scientist. The individual with hearing loss has adapted to wearing hearing aids over the last five years. Issues that have occurred affecting comprehension along with compensatory strategies that assisted listening and comprehension will be discussed.
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Bauch, Christopher D. "Brain Stem Auditory Evoked Potentials in Peripheral Acoustic Disorders." In Clinical Neurophysiology, 305–10. Oxford University Press, 2009. http://dx.doi.org/10.1093/med/9780195385113.003.0021.
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Hearing sensitivity in the 2000–4000 Hz range is important to BAEP assessment. Absolute latencies and interaural latency differences are often affected by increasing degrees of hearing loss in this frequency range, whereas interpeak intervals are relatively stable measures, even for patients with moderate-to-severe degrees of peripheral hearing loss. However, the reduction in amplitude or the absence of a measurable wave I associated with peripheral hearing losses often makes it difficult or impossible to measure I–III or I–V intervals. Overall sensitivity of BAEP is 92% for patients with a CN VIII tumor. The false-positive rate for patients with cochlear hearing loss is 12%. Tumor size influences BAEP test results: the sensitivity is 100% for CN VIII tumors larger than 2 cm, but it is only 82% for CN VIII tumors 1 cm or smaller.
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Brock, Penelope, Kaukab Rajput, Lindsey Edwards, Annelot Meijer, Philippa Simpkin, Alex Hoetink, Mariana Kruger, Michael Sullivan, and Marry van den Heuvel-Eibrink. "Cisplatin Ototoxicity in Children." In Hearing Loss - From Multidisciplinary Teamwork to Public Health. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96744.
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Cisplatin is a highly effective chemotherapy medicine used in the treatment of many childhood cancers. Like all medications, cisplatin has many side effects and as always the treatment of cancer in children is a balance between the risks of the medications used and their potential benefits. While many side effects of cisplatin chemotherapy are reversible, one major side effect is permanent and irreversible hearing loss (ototoxicity) in both ears which may worsen with time. The severity of cisplatin-related ototoxicity is associated with age and the cumulative dose received: the younger the child and the higher the total dose, the more severe the hearing loss may be. The spectrum of hearing loss varies from mild to moderate high tone hearing loss, to profound loss across the hearing range and permanent deafness. In addition to hearing loss, some children, especially adolescents, also experience tinnitus and vertigo. Cisplatin ototoxicity is one of most important of the many long-term effects experienced by children who are cured of their cancer. The burden of this toxicity may be compounded by other long-term health issues that emerge with time. This chapter will focus on cisplatin-induced hearing loss, its mechanisms, its health impact on the young person and ways to mitigate or reduce the severity of ototoxicity. This chapter has been written by a multi-disciplinary team including paediatric oncologists, audiologists, a psychologist, a health scientist and a parent of a child growing up with high frequency hearing loss.
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Devine, Michelle F., Divyanshu Dubey, and Sean J. Pittock. "Hearing Loss, Imbalance, and Diplopia in a 44-Year-Old Man." In Mayo Clinic Cases in Neuroimmunology, edited by Andrew McKeon, B. Mark Keegan, and W. Oliver Tobin, 105–7. Oxford University Press, 2021. http://dx.doi.org/10.1093/med/9780197583425.003.0032.
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A 44-year-old man sought care for new right-sided tinnitus and sensorineural hearing loss. He was treated with high-dose oral prednisone and acyclovir. Later, mild, intermittent dizziness developed, which progressed to constant, moderate dizziness and was exacerbated by sudden head movements. He participated in vestibular rehabilitation with only mild improvement. Within 5 months of tinnitus onset, horizontal binocular diplopia also developed. Examination showed spontaneous left-beating torsional nystagmus in primary gaze, down-beating nystagmus with leftward gaze, and right-beating torsional nystagmus in rightward gaze. Head impulse testing to the right produced a catch-up saccade. Dix-Hallpike maneuver in both positions led to leftward torsional nystagmus followed by down-beating nystagmus. He had full range of eye motion. There was evidence of asymmetric hearing loss on the right and moderate gait unsteadiness; he was able to complete only a few steps in tandem. Neurologic examination findings were otherwise normal. Oculomotor testing demonstrated abnormalities supportive of a central nervous system disorder. These included excessive square-wave jerks, impaired smooth pursuit, and direction-changing nystagmus. Results of cerebrospinal fluid studies included a normal opening pressure, pleocytosis, and increased protein concentration. Serum and cerebrospinal fluid paraneoplastic evaluations showed a unique immunofluorescence staining pattern on rodent brain tissue by patient immunoglobulin G, which was later confirmed to be immunoglobulin G antibodies to kelch like family member 11. Whole-body positron emission tomography showed a single anterior mediastinal mass, which was then resected. The patient was diagnosed with a paraneoplastic anti-kelch like family member 11 rhombencephalitis with an extratesticular seminoma. After removal of the mediastinal mass, intravenous methylprednisolone was started. The patient had symptom stabilization but no clinical improvement. Cyclophosphamide was added to the weekly pulse-dose intravenous corticosteroids. He had mild improvement in vertigo and gait imbalance. For symptomatic management of the vertigo, he received baclofen, citalopram, and vestibular rehabilitation. He continued to have slow improvement. After approximately 1 year of cyclophosphamide treatment, his gait normalized and nystagmus diminished, although he had persistent neurologic deficits including spontaneous down-beating nystagmus and a few intermittent square-wave jerks. The intravenous methylprednisolone infusions were tapered, with continued examination stability. After stable symptoms and examination findings, cyclophosphamide was discontinued. After discontinuation of cyclophosphamide, new central sensorineural hearing loss developed suddenly in his left ear. This improved with additional intravenous methylprednisolone treatment. Mycophenolate mofetil was also started, and corticosteroids were tapered. Repeated positron emission tomography of the body showed no recurrence of seminoma. Symptoms and audiography findings were stable after 10 months, so the patient elected to discontinue immunosuppression again and has remained stable. Kelch like family member 11 autoimmunity is a distinct paraneoplastic syndrome associated with encephalitis and testicular germ cell tumors (including seminoma).
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Nogara, Pablo A., Meire E. Pereira, Claudia S. Oliveira, Laura Orian, and João B. T. da Rocha. "The Long Story of Ebselen: From about One Century of its Synthesis to Clinical Trials." In Chalcogen Chemistry: Fundamentals and Applications, 567–91. The Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/bk9781839167386-00567.
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The first synthesis of Ebselen was nearly a full century ago, but despite several clinical trials with Ebselen, the therapeutic application of Ebselen is still uncertain. Nevertheless, it has very low toxicity and its broad activity in the modulation of the redox equilibrium indicates that Ebselen can be a multitarget therapeutic agent against human diseases. Here we will review nearly a dozen clinical trials with Ebselen to treat brain ischemia, cardiovascular problems associated with diabetes mellitus, noise-induced hearing loss, and bipolar disorder. The molecular events potentially mediating the effects of Ebselen will be discussed. The approved but still not initiated clinical trials (the studies are in the recruiting phase) to treat moderate and severe COVID-19 are highlighted.
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Marcrum, Steven C., Erin M. Picou, Thomas Steffens, Ronny Hannemann, Veronika Vielsmeier, Martin Schecklmann, Berthold Langguth, and Winfried Schlee. "Conventional versus notch filter amplification for the treatment of tinnitus in adults with mild-to-moderate hearing loss." In Progress in Brain Research. Elsevier, 2020. http://dx.doi.org/10.1016/bs.pbr.2020.06.020.
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Wright, Barry. "Cognitive and Behavioral Complications of Deafness." In Cognitive and Behavioral Abnormalities of Pediatric Diseases. Oxford University Press, 2010. http://dx.doi.org/10.1093/oso/9780195342680.003.0064.
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The prevalence of profound deafness in the United Kingdom is reported as 9 per 10,000 in 3-year-olds to 16 per 10,000 in 9- to 16-year-olds, although it is estimated that these figures may be higher because of possible under-diagnosing (Fortnum et al. 2001). In England and Scotland, approximately 13 in 10,000 children have a permanent hearing impairment of 40 dB or more (moderate to profound) across the frequencies 500–4,000 Hz (Fortnum and Davis, 1997; Fortnum, 2003; Kennedy and McCann, 2008; MacAndie et al. 2003) and in 11 in 10,000 this loss is congenital. The remainder are acquired or progressive. Profound impairment (≥95 dB loss) occurs in 2.4 per 10,000. Bilateral sensorineural deafness had a prevalence of 21 per 10,000 in a Finnish birth cohort (1974–1987) (Vartiainen, Kemppinen, and Karjalainen 1997). A survey in the general population in Sichuan, China, found a prevalence of 1.9 per 1,000 profound deafness (Liu et al. 1993). Table 44.1 shows the World Health Organization (WHO) and British Society of Audiology definitions of degrees of deafness. Sensorineural deafness involves problems either in hair cell function in the cochlear or in the nerve transmission of sound. For bilateral sensorineural deafness, the diagnosis is made at variable ages in health systems in which there is no universal neonatal screening. This varies across cultures, but can still be surprisingly late even in modern health systems. One study of 106 children with bilateral sensorineural deafness showed a mean age for first diagnosis at 42 months (median 33 months) of age, with a range from 4 months to 11 years of age (Walch 2003). In another study in Glasgow, Scotland (Chaurasia and Geddes, 2008), only 50% of early childhood deafness presented before 2 years of age. Conductive deafness involves problems with sound travelling from the outer ear, through the middle ear, to the cochlear. The commonest cause is otitis media (“glue ear”), with losses usually in the mild to moderate range. About half of children between 2 and 4 years will have at least one episode of otitis media with effusion (OME) (Zielhuis, Rach, and Van den Brock 1990).
Conference papers on the topic "Moderate hearing loss"
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Moya, Manoel Vilela, Mariana Laranjeira Pierotti, and Alyosha Fabiana Rodrigues. "Relationship between hearing loss and cognitive memory decline in an elderly population." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.666.
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Background: The major complaints of the elderly are hearing and memory loss, which have a devastating impact on the communication process. Previous studies have shown that hearing loss is associated with the acceleration of this cognitive decline. Objectives: To analyze the relationship between moderate to moderatelysevere hearing loss and memory deficit in elderly individuals. Design and setting: This is an observational, cross-sectional study realized in seniors of Hearing Care Program at the Taubaté University Hospital, Taubaté - SP/ Brazil. Methods: Data was collected using audiometry, anamnesis, and the cognition test Mini Mental State Examination (MMSE) in 60-75 years old individuals, without knowledge of previous cognitive memory deficit and without the use of hearing aids. Results: Between the 61 seniors interviewed, 68% had moderate degree of deafness and 32% moderately severe degree. Among the normal results in the MMSE, 24% had moderately severe deafness; of those with cognitive impairment without indication of investigation of dementia, 35.7% had moderately severe deafness, and of those with indication of investigation of dementia, 50% had moderately severe deafness. In addition, 23% of the total sample had results in the normal cutoff range, showing the tendency for cognitive decline in this population. Conclusions: these data indicate a progression in the proportion of individuals with a higher degree of hearing loss, the higher the cognitive deficit.
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Silva, Vitória Pimentel da, Lucas Immich Gonçalves, Giordani Rodrigues dos Passos, Maísa Kappel, Mayumi Charão, and Jefferson Becker. "Vogt-Koyanagi-Harada Syndrome: case report." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.637.
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Context: Red eye complaints are common in medical practice. Trauma, infection and autoimmune disorders are possible causes. It is essential to diagnose early to avoid sequelae. Case report: Female, 58 years old, 30 days of progression of bilateral frontal and retro-orbital headache associated with red eye and decreased visual acuity in both eyes, otalgia and tinnitus in the left ear. No trauma history. She started treatment in another hospital with acyclovir for suspected viral meningitis and was referred for evaluation after 10 days due to the lack of improvement. In our evaluation, the patient had severely impaired visual acuity (counted fingers in the RE and 20/400 in the LE), with uveitis, papilloedema and bilateral serous retinal detachment. Lumbar puncture showed aseptic meningitis (940 leukocytes with 100% lymphocytes, 66 mg/dL proteins, normal glucose and negative evaluation for CSF infections). Laboratory tests showed an increase in inflammatory markers (VSG 121) and positive anti-TPO, with other negative autoantibodies. Brain MRI with subacute retinal detachment, without intracranial lesions. Audiometry with mild to moderate bilateral sensorineural hearing loss. The patient was treated with IV methylprednisolone for 5 days with partial symptom improvement. Conclusion: Among the bilateral uveitis causes, it is crucial to remember Vogt-Koyanagi-Harada Syndrome (VKH), which occurs through bilateral uveitis, sometimes accompanied by retinal detachment, in association with hypochromic skin lesions, sensorineural hearing loss, headache and aseptic meningitis2 . VKH results from an autoimmune lesion in the melanocytes3 . Treatment should be done with topical corticosteroid, associated with cycloplegics and systemic corticosteroid therapy with long-term immunosuppression2.
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Giliberti, Claudia, Fabio Lo Castro, Maria Patrizia Orlando, Raffaele Mariconte, and Maurizio Diano. "Use of hearing aids at work: results of a questionnaire for the analysis of comfort and perceived benefit." In 13th International Conference on Applied Human Factors and Ergonomics (AHFE 2022). AHFE International, 2022. http://dx.doi.org/10.54941/ahfe1001640.
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Almost 460 million world people live with moderate to severe hearing loss (HL), with noise the most common cause, particularly in the workplace. Noise-induced HL is still one of the most prevalent recognized occupational diseases, but in Italy, it is no longer at the first ranks, thanks to technical and organizational solutions adopted to reduce noise in the work environment after 2008. In particular, Italian surveillance system data show that Construction is the work sector in which HL is most present (28% of cases), followed by Manufacture (17%). HL can compromise social life, causing isolation, frustration, depression, and even cognitive decline, while in the workplaces could affect workers’ safety, representing an important injury risk factor. The use of hearing aids (HA) represents an effective preventive action. In Italy, there are at least 7 million hearing-impaired people, but only 29.5% wear an HA (2018 data). Their use appears to be more widespread in the older age groups, while the least use is found from 45 to 64 years (20.8%) which refers to professionally active people. Many aspects prevent the use of an HA, among these, technical and psychological reasons. The objective of this study is to evaluate the degree of comfort/discomfort and the perceived benefit of using an HA, particularly in working environments.MethodsAn ad hoc questionnaire consisting of 10 questions, five on the working sphere and five on perception, was developed. The former investigated the acoustic comfort of the work environment, use of HA, hearing protectors, accessories, and the information received on the correct use of HA at work; the second investigated the satisfaction of the prosthetic solution, the improvement in the perception of speech or the sounds direction and danger signals to avoid accidents at work. The answer options for each question were yes / sometimes / no. Further information on gender, age, type of job, years of work, type of HA and years of use, type of hearing damage, was collected. The professions were grouped into seven categories: construction workers, freelancers, health professions, teachers, office workers, traders, others, which were further classified on noise exposure and hearing risk into High risk (construction workers), Medium risk (teachers, traders), Low risk (freelancers, health professions, office workers). The results were statistically analyzed.ResultsThe questionnaire was administered to 141 workers (55 females and 86 males) with an average age of 57 years (minimum 21, maximum 82). The sample shows prevalently bilateral sensorineural HL, works for about 30 years, wears an HA from 6 years, mainly “in the ear” type (77%), mostly employed as freelancers (21%), office workers (19%), construction workers (18%).For high-risk employees, the use of an HA with personal protective equipment has been discussed, taking into account the issue regarding the protection of these prosthetic workers in noisy work environments. The results show that special attention should be paid to the optimization of the prosthesis for this category of workers, most acoustically exposed, taking into account their comfort, perceived safety, and satisfaction.
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Lavrentjev, Jüri, and Hans Rämmal. "Acoustic Study on Motorcycle Helmets with Application of Novel Porous Material." In Small Engine Technology Conference & Exposition. 10-2 Gobancho, Chiyoda-ku, Tokyo, Japan: Society of Automotive Engineers of Japan, 2020. http://dx.doi.org/10.4271/2019-32-0531.
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<div class="section abstract"><div class="htmlview paragraph">A critically high noise level inside protective helmet is a prevalent concern for motorcyclists. Especially at highway speeds where the noise level, regardless of helmet type can exceed 100 dB(A) and approaches threshold of discomfort, often resulting in temporary hearing loss. Despite of large share of persons exposed to such noise disturbance around the world, the in helmet noise levels have not significantly decreased over the last decades. Only few scientific publications can be found to systematically address this issue. Furthermore, in respect of driving safety even moderate noise levels are reported to impair reaction times and reduce attention of motorcyclists. At higher speeds the dominant helmet noise source is linked to aerodynamic turbulence around the helmet shell. The loudness and spectral contents mainly depend on the driving speed, windscreen configuration, riding position and helmet geometry. In this paper a series of on-road tests and laboratory experiments with three main types of helmets (“full face”, “flip up” and “open face” type) have been performed with the focus on in-helmet acoustics. Noise spectra at the location of rider's ears are measured, the results are analyzed and the noise source mechanisms are studied. A novel acoustic material, consisting of reticulated natural leather foam is presented for helmet noise control applications. It is demonstrated that a remarkable helmet noise level reduction can be achieved in a wide frequency range by the material into the critical interior regions of motorcycle helmets.</div></div>
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Gvozdeva, Alisa Petrovna, Evgenia Alexandrovna Klishova, Vladimir Masgutovich Sitdikov, Larisa Evgenievna Golovanova, and Irina Germanovna Andreeva. "Minimal time to determine direction of azimuthally moving sounds in moderately severe sensorineural hearing loss." In 180th Meeting of the Acoustical Society of America. ASA, 2021. http://dx.doi.org/10.1121/2.0001451.
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Jiana Santos, Ezri, Diana Marie De Silva, Haerold Dean Layaoen, John Kenneth Punongbayan, and Josefa Angelie Revilla. "Evaluation of electromagnetic hypersensitivity (EHS) of Business Process Outsourcing (BPO) employees under traditional and remote work environments." In AHFE 2023 Hawaii Edition. AHFE International, 2023. http://dx.doi.org/10.54941/ahfe1004317.
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Following the success of remote work in the Business Process Outsourcing (BPO) industry during the Covid-19 pandemic, several organizations have considered choosing a permanent remote work policy for their employees over the traditional face-to-face setup. The primary determinants that dictate adopting a permanent working environment are often centered on cost-related considerations with little regard for the slow onset of occupational health hazards. Studies have identified various health hazards experienced by BPO personnel, including headaches, back pain, neck and shoulder discomfort, wrist and hand pain, eye strain, overweight, hearing loss, and digestion issues. Electromagnetic hypersensitivity (EHS) is a term used to describe such symptoms that manifest in response to exposure to electromagnetic field (EMF)-emitting devices. In the context of the Philippines, most are unaware of the potential implications of EMF exposure, hence it is worthwhile to closely investigate the EHS of BPO employees. This study aims to investigate the health-effects of EMF-emitting devices on BPO personnel in both traditional and remote work setups. The study used a web-based questionnaire to collect and assess data from two discrete populations. A self-reporting questionnaire (SRQ-20) was used to pre-assess the respondents’ general wellness and health status. Statistical significance was established using the independent t-test. Principal component analysis was used to identify the major symptoms associated with EHS, whereas the EMF sources were analyzed using an independent sample t-test with bootstrapping. Based on the SRQ-20, traditional BPO personnel encounter health risks with statistically higher severity (p < 0.05) than their remote counterparts which may infer that the two different working settings possibly have distinct effects on the health of the workers. However, upon further evaluation, the two distinct populations both exhibited negligible to moderate indications of EHS symptoms in separate environments. A significant difference in the perception of BPO workers is observed regarding the intensity of the effects of EMF across all possible sources except three specific devices: a computer, a television, and a television or radio transmitter. However, the source analysis indicates that the influence of EMF-emitting devices on the EHS of employees is low to negligible in both occupational settings. The study concluded that there is an absence of potential health risks stemming from exposure to EMF in both occupational settings for BPO employees. Considering the negligible impact of EMF exposure on EHS symptoms, BPO industries possess the flexibility to choose between the two work setups, as both environments do not pose significant EMF-related occupational health and safety threats.