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1
Yousef, Mohammad. "Mise en évidence de quelques relations entre la régulation de la balance hydrominérale et les cycles de reproduction chez les amphibiens." Thesis, Lyon, 2016. http://www.theses.fr/2016LYSE1319.
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Les amphibiens sont des vertébrés liés aux alternances entre la vie aquatique et la vie terrestre et aux alternances saisonnières. Le développement embryonnaire commence par une phase aquatique et se termine par une métamorphose qui donnera une forme juvénile terrestre pouvant rester dans le milieu aquatique chez certaines espèces retournées secondairement à la vie aquatique. Les cycles de reproduction sont régulés, entre autres, par les hormones hypophysaires: LH et FSH (gonadotropes) et PRL (prolactine). La régulation hydrominérale des vertébrés est également assurée par des hormones neurohypophysaires telles que l'arginine vasopressine (AVP), l'ocytocine (OT), l'arginine vasotocine (AVT), la mésotocine (MST) et l'isotocine (IST). Le but du travail effectué dans le cadre de cette thèse a été d'apporter quelques éléments de compréhension des liens pouvant exister entre la reproduction et la régulation hydrominérale. Les cycles de reproduction de Typhlonectes compressicauda sont soumis à des alternances saisonnières caractérisées par une saison des pluies et une saison sèche.Dans le présent travail nous avons mis en évidence les principales hormones impliquées dans la régulation de la balance hydrique (AVT, MST). Parallèlement, une étude précise de la structure des reins avec la mise en évidence des récepteurs de différentes hormones concernées a été menée. La mise en évidence par biochimie (western blot et dosage) des différentes hormones et de leurs récepteurs (immunohistochimie) a également été effectuée chez Xenopus laevis, espèce aquatique représentant un modèle d'étude conventionnel, de manière à apprécier l'implication de ces hormones lorsque l'animal termine sa métamorphoseThe amphibians are vertebrates the cycle of life being related to both the alternations between aquatic and terrestrial phases and seasonal alternations. Embryonic development begins with an aquatic phase and completed with a metamorphosis, at the end of which terrestrial juveniles animals can persist in the aquatic environment in secondary aquatic species. The breeding cycles are regulated by the pituitary hormones: LH, FSH (gonadotropins) and PRL (prolactin). The hydromineral regulation of vertebrates is also ensured by neurohypophysial neurohormones such as arginine vasopressin (AVP), oxytocin (OT), vasotocin (AVT), mesotocin (MST), and isotocin (IST).The work in the context of this thesis was to bring some elements for understanding the relationships that may exist between the reproduction and hydromineral regulations.The reproductive cycles in Typhlonectes compressicauda are submitted to seasonal alternations characterized by a rainy season and a dry season. In the present work we highlighted the main hormones involved in the regulation of hydric balance in amphibians (AVT, MST). In parallel, a precise study of the structure of the kidneys with the identification of receptors of various hormones concerned, was performed. The identification of both various hormones and their receptors by biochemistry (Western blot, assay) and immunohistochemistry was also performed on Xenopus laevis, an aquatic species representing also a conventional model for the study, in way to appreciate the implication of these hormones when the animal completes its metamorphosis
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Melka, Johanna. "Répercussion des fluctuations du taux de change sur les prix des firmes exportatrices : une mise en évidence des comportements de "pricing-to-market" et de leurs conséquences macro-économiques." Paris 1, 2000. http://www.theses.fr/2000PA010063.
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Cette thèse analyse en termes théoriques et empiriques, les comportements de prix des firmes exportatrices face aux variations du change. Nous cherchons à mettre en lumiere l'adoption de comportements de pricing-tomarket et à étudier leurs conséquences d'un point de vue macro-économique. Nous analysons dans un premier chapitre les facteurs qui incitent la firme à ne pas répercuter les variations de change sur ses prix de vente, autrement dit à adopter un comportement de pricing-to-market. Nous appuyons nos conclusions théoriques par une analyse empirique du comportement de répercussion des firmes françaises et allemandes en Europe, aux États-Unis et au Japon, sur le secteur automobile, dans un deuxième chapitre. Nous parvenons à montrer que les firmes françaises et allemandes adoptent une stratégie de pricing-to-market conditionnée au pays client et au produit vendu. Nous montrons de plus, en utilisant les modèles à seuil dans un troisième chapitre, que le sens et l'ampleur des variations de change déterminent la stratégie de la firme exportatrice. Une telle strategie n'est pas neutre quant à l'impact des politiques macro-économiques sur les économiques puisqu'elle suppose que les prix des biens en monnaie de l'acheteur sont rigides alors que les modèles traditionnels de macro-économie les considèrent flexibles. À ce titre, dans un dernier chapitre, nous montrons que si les firmes exportatrices ne repercutent pas les variations de change sur leurs prix de vente, alors une dévaluation peut non seulement avoir un impact défavorable sur la balance commerciale du pays dévaluateur, mais aussi entrainer une suréaction du taux de change.
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Fourment, Victoria. "Le contrôle de proportionnalité à la Cour de cassation : l’office du juge à l’épreuve de la mise en balance et du contrôle de conventionnalité." Electronic Thesis or Diss., Aix-Marseille, 2022. http://scd-proxy.univ-brest.fr/login?url=https://bibliotheque.lefebvre-dalloz.fr/isbn/9782247234455.
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Depuis 2013, la Cour de cassation exerce un contrôle de proportionnalité des atteintes portées par l’application de la loi aux droits fondamentaux des individus garantis par la Convention européenne des droits de l’homme. Ce contrôle s’exerce dans des domaines aussi divers que la validité du mariage entre alliés, le droit du travail ou les infractions pénales. L’originalité de ce contrôle de conventionnalité de la loi appliquée au cas d’espèce (in concreto) vient du fait qu’il permet d’évincer la loi pour trancher le litige. L’objet de la thèse est d’interroger et d’évaluer cette innovation. Celle-ci se situe à la croisée de deux visions opposées des droits fondamentaux. Selon un modèle classique, les droits fondamentaux sont conçus comme des « boucliers » que détiennent les individus vis-à-vis de l’action de l’État. Ils ont donc vocation à s’appliquer dans un rapport vertical ou hiérarchique vis-à-vis d'un pouvoir, rapport qui ne se retrouve pas dans les litiges entre individus sauf pour le contrat de travail. Selon un modèle plus récent, les droits fondamentaux sont mis sur un pied d’égalité avec la loi, ce qui implique leur « mise en balance » pour déterminer l’issue du litige. Cette méthode, normalement réservée aux rapports interindividuels, s’adapte mal au contrôle hiérarchique de la loi que la Cour de cassation souhaite opérer. La recherche conclut à la nécessité de respecter l’opposition des deux modèles pour conditionner l’extension du champ d’application du contrôle de proportionnalité aux rapports qui opposent l’individu à la loi. Le cantonnement au seul contrôle abstrait de conventionnalité apparaît alors déterminant pour mettre fin à une telle extensionSince 2013, the Cour de cassation has been exercising proportionality over the infringement of the fundamental rights of individuals guaranteed by the European Convention on Human Rights. This control is exercised in areas as diverse as the validity of marriage between spouses, labour law or criminal offences. The originality of this control of conventionality of the statute applied to the case (in concreto) comes from the fact that it makes it possible to bypass the statute in order to settle the case. The purpose of this thesis is to question and evaluate this innovation. Indeed, it lies at the crossroads of two opposed visions of fundamental rights. According to a classical model, fundamental rights are conceived as “shields” held by individuals against state interference. They are therefore intended to be applied in a vertical or hierarchical relation to a power, a relation that is not found in disputes between individuals except for the employment contract. According to a more recent model, fundamental rights are placed on an equal level with a statute, which implies that they are “weighed up” to resolve the issue. This method, which is normally reserved for inter-individual relations, does not fit with the hierarchical control of the statute that the Cour de cassation wishes to apply. The research therefore concludes that it is necessary to respect the opposition of the two models to condition the extension of the scope of application of the proportionality review to the relation between the individual and the law. The confinement to the sole abstract control of conventionality then appears to be a determining factor in putting an end to such an extension
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Haccoun, Alexis. "La mise en balance des libertés et de la sécurité dans le cadre du contrôle juridictionnel des mesures antiterroristes : l'exemple de la Cour suprême israélienne." Aix-Marseille 3, 2010. http://www.theses.fr/2010AIX32072.
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Les "attentats hécatombes" dans des grandes métropoles occidentales (New York, Londres, Madrid) ont suscité l'adoption par des Etats démocratiques de dispositifs antiterroristes dont le caractère liberticide a rendu nécessaire le contrôle juridictionnel des juges. Ce dernier, qui se fonde massivement sur l'instrument de la mise en balance (ou critère de proportionnalité), traduit une rupture avec l'approche juridique déontologique traditionnelle et marque l'adhésion à une logique instrumentaliste où la légalité de l'atteinte aux libertés individuelles est appréciée en référence aux gains sécuritaires escomptés du fait de la mesure incriminée. Ce passage à une logique instrumentaliste s'inscrit dans une tendance structurelle de recours croissant à ce type de rationalité, en théorie politique, pour évaluer la pertinence d'un choix collectif ou individuel: ce positionnement invite à penser la mise en balance en liaison avec ce vaste ensemble théorique dans le cadre d'une approche transdisciplinaire et à mettre à jour les échanges entre la pratique juridique et la théorie de la décision. Cette étude, qui s'appuie sur le cas de la Cour suprême d'Israël, met en évidence le rôle fondamental des concepts issus de la théorie de la décision (analyse marginale. . . ) dans l'usage de la mise en balance et met en question la possibilité d'une création ex nihilo par les juristes. En retour, elle montre en quoi la mise en balance peut nourrir la réflexion théorique sur la question des choixThe slaughter bombings on Western cities (New York, London, Madrid) has provoked the adoption by democracies of counterterrorist legislations whose restrictions on liberties imposed judicial review by national Courts. This review, based on the principle of the "balancing test" (or "proportionality test"), represents an upset of the traditional deontological judicial approach and marks the adhesion to a consequentialist view in which the legality of the restriction to the individual liberties is evaluated in reference to the anticipated benefits on security of the incriminated act. The adoption by the judges of a consequentialist posture come within the framework of a broad tendency of increasing resorting to this kind of rationality in political theory to evaluate the relevance of an individual or public choice: this location invites to study the balancing test in link with this broad theoretical whole in the framework of a transdisciplinary approach and to bring to the fore the exchanges between the balancing test and the choice theory. This work, which rely on the case of the Israel Supreme Court, emphasizes the fundamental role of the concepts stemming from the choice theory (marginal analysis. . . ) in the use of the balancing test and challenge the idea of a ex nihilo creation. In return, it shows how the balancing test can improve the study of the choice theory
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Pelletier, François. "Mise au point d'observateurs d'état pour le suivi de cultures de cellules animales." Vandoeuvre-les-Nancy, INPL, 1995. http://www.theses.fr/1995INPL135N.
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L’objectif de ce travail est l'élaboration d'outils d'estimation d'état simples d'emploi pour l'évaluation de la composition des milieux de culture cellulaires. La première partie concerne le développement d'un nouvel estimateur appelé observateur à base de bilans de matière construit sur le principe de l'observateur asymptotique. Il peut être appliqué à n'importe quel type de culture. Il ne nécessite aucun réglage. La possibilité de prendre en compte certaines lois cinétiques connues permet de le faire fonctionner avec un nombre restreint de mesures. La seconde partie traite de la mise au point d'une nouvelle variante du filtre de Kalman, le filtre de Kalman auto-ajustable. Le réglage du filtre de Kalman est délicat et peut conduire à des problèmes de stabilité de l'erreur d'estimation et de convergence des valeurs estimées vers les valeurs réelles. Le filtre de Kalman auto-ajustable assura la stabilité des erreurs d'estimations avec un nombre réduit de réglages. Les deux nouveaux observateurs ont été appliqués à trois cultures d'hybridomes productrices d'anticorps monoclonaux. À partir de deux mesures expérimentales (glucose et lactate déshydrogénase ou ammoniaque et lactate déshydrogénase), la composition du milieu de culture est évaluée par les deux techniques. L’observateur à base de bilans de matière a donné de bons résultats et ceux obtenus avec le filtre de Kalman auto-ajustable sont acceptables tant que l'on ne sort pas du domaine de validité du modèle
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Koubi, Rufin Médard. "Rôle de la représentativité dans la mise en œuvre et la dynamique de la gouvernance des universités françaises de 1968 à nos jours." Thesis, Limoges, 2014. http://www.theses.fr/2014LIMO0047.
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Depuis 1968, la gestion des universités françaises connaît de nombreuses et diverses évolutions. En 2007, l’adoption de la loi relative aux Libertés et Responsabilités des Universités, donne à la gouvernance une nouvelle orientation philosophique et pratique. Celle-ci consacre désormais l’affaiblissement du législatif face à l’exécutif et le renforcement des pouvoirs du Président de l’université qui s’appuie davantage sur une stratégie managériale. Ce nouveau contexte bouleverse l’équilibre des pouvoirs institutionnellement établis dans le champ universitaire. Cette évolution engendre une tension entre la présidentialisation connotée de la logique managériale et la collégialité qui constitue la base historique de l’administration des universités françaises. Le rôle réel de la représentativité dans la gouvernance des dites universités est ainsi posé. Trois universités de tailles différentes, Strasbourg, Limoges et Nîmes font l’objet d’une étude à partir d’entretiens semi directifs avec les acteurs concernés par le « rôle de la représentativité dans la mise en oeuvre et la dynamique de la gouvernance des universités »Since 1968, management of French universities has many and various developments. In 2007, the adoption of the Law on Civil Liberties and Responsibilities of Universities, gives to the governance a new philosophical and practical guidance. The adoption of the Law on Civil Liberties and Responsibilities of Universities, gives governance a new philosophical and practical guidance. That law now shifting the weakening of the legislative face to the executive and the strengthening of the powers of President of the university who leans more on a managerial strategy. This new context upsets the balance of power institutionally established in the university field. This evolution engenders a tension between the Presidentialization connoted by the managerial logic and the corporatism which constitutes the historic basis of the administration of the French universities. This is the real role of representation in the governance of these Universities. Three universities with different sizes, Strasbourg, Limoges and Nimes are the subjects of a study from semi-directive interviews with The Concerned Actors For The "role of representation in the implementation and dynamics of the universities governance."
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Ameline, Maël. "Diagnostic hydrique et estimation de la production de la culture de maïs : vers la mise en place d'un service tout temps." Thesis, Toulouse 3, 2019. http://www.theses.fr/2019TOU30314.
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La thèse répond aux objectifs d'évaluer le potentiel d'estimation de la production de parcelles de maïs, ainsi que de leurs besoins hydriques. Les travaux, validés dans le Sud-Ouest de la France, reposent sur le couplage du modèle agro-météorologique à de l'imagerie satellitaire pour étendre le suivi à une échelle régionale. Le but est de s'affranchir des contraintes nuageuses imposées sur les acquisitions optiques, grâce à l'utilisation du radar Sentinel-1. L'estimation de la production comprend la biomasse sèche (épi, plante) ainsi que le rendement à l'échelle parcellaire. Au-delà des améliorations du modèle, l'assimilation combinée de l'optique et du radar donne de bons résultats et améliore les simulations basées sur l'optique en comblant l'absence de données en début de saison (forte nébulosité). Les résultats de l'estimation du contenu en eau sont plus contrastés. Le détail des erreurs révèle notamment des défauts liés aux propriétés du sol ou aux déclarations des agriculteursThe study explores the feasibility to estimate the corn field production and its water needs during the irrigation period. The work, validated in the South-West of France, is based on an agro-meteorological model coupled with satellite imagery to extend monitoring to regional scale. The recent availability of Sentinel-1 radar mission allows monitoring without atmospheric constraints (e.g. clouds) as opposed to optical acquisitions. The estimation of production is linked with dry biomass (ear, plant) and yield data at the field scale. Beyond new improvements, the combination of optical and radar provides accurate results and even improves the estimations based on optical by filling the gaps caused by cloud cover at the beginning of the season. The water needs simulation are more contrasted as a result of the accuracy of the input data. Moreover, some features (e.g. soil properties) can be seen within soil moisture measurements, even though they cannot be modeled
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Rouaux, Caroline. "Etude du rôle de la balance HAT/HDAC dans les phénomènes de neurodégénérescence : Mise en évidence du rôle neuroprotecteur de CBP et des effets thérapeutiques des inhibiteurs de HDAC sur un modèle murin de sclérose latérale amyotrophique." Université Louis Pasteur (Strasbourg) (1971-2008), 2006. https://publication-theses.unistra.fr/public/theses_doctorat/2006/ROUAUX_Caroline_2006.pdf.
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L’apoptose neuronale peut s’enclencher de manière inappropriée lors de maladies neurodégénératives. Elle requiert un programme génétique dont l’activation résulte notamment de régulations épigénétiques comme l’acétylation des histones. L’objectif de cette thèse était d’évaluer le rôle des histone acétyltransférases (HATs)/histone déacétylases (HDACs) dans la survie et la mort neuronale. Les résultats, obtenus dans un modèle d’apoptose neuronale in vitro, et dans un modèle murin de sclérose latérale amyotrophique (maladie neurodégénérative d’issue fatale affectant les motoneurones) convergent vers la perte d’une HAT particulière, CBP, et une diminution des niveaux d’acétylation, selon deux nouveaux mécanismes : clivage par la caspase-6 et répression transcriptionnelle. L’inhibition des HDACs par le valproate de sodium s’avère neuroprotectrice in vitro et in vivo, permet l’amélioration de l’état de santé des animaux et est encourageante dans le traitement des maladies neurodégénérativesNeuronal apoptosis (programmed cell death) occurs pathologically in neurodegenerative diseases. It requires a specific genetic program whose application results at least partly from epigenetic regulations such as histone acetylation. The aim of this thesis was to evaluate the role of histone acetyltransferases (HAT) and histone deacetylases (HDAC) in neuronal survival and death. Our results, obtained in a simplified cellular model of neuronal apoptosis and in a in vivo model of amyotrophic lateral sclerosis (ALS) (a fatal neurodegenerative disease that affects motor neurons) point to the loss of a specific HAT, CBP, and histone deacetylation, according to two new mechanisms: caspase-6-mediated proteolytic cleavage and gene repression. HDAC inhibition by sodium valproate maintains proper acetylation levels, displays neuroprotective functions both in vitro and in vivo, increases animals sate of health and is then very promising as a therapeutic strategy in neurodegenerative diseases
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Rouaux, Caroline Boutillier Anne-Laurence. "Etude du rôle de la balance HAT/HDAC dans les phénomènes de neurodégénérescence Mise en évidence du rôle neuroprotecteur de CBP et des effets thérapeutiques des inhibiteurs de HDAC sur un modèle murin de sclérose latérale amyotrophique /." Strasbourg : Université Louis Pasteur, 2008. http://eprints-scd-ulp.u-strasbg.fr:8080/908/01/ROUAUX_Caroline_2006.pdf.
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Thèse doctorat : Sciences du vivant. Aspects Moléculaires et Cellulaires de la Biologie : Strasbourg 1 : 2006.Thèse soutenue sur un ensemble de travaux. Titre provenant de l'écran-titre. Bibliogr. 34 p.
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Savoye, François Paul. "Impact des impulsions périodiques de courant sur la performance et la durée de vie des accumulateurs lithium-ion et conséquences de leur mise en oeuvre dans une application transport." Thesis, Lyon 1, 2012. http://www.theses.fr/2012LYO10027/document.
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Ce travail vise à identifier l’impact potentiel des impulsions périodiques de courant sur laperformance et la durée de vie des accumulateurs graphite/LiFePO4. Il apparait que,contrairement aux résultats connus pour les accumulateurs Plomb-acide et à ceux annoncéspar certains auteurs de la littérature pour les accumulateurs Li-ion, l’application d’impulsionspériodiques de courant ne présente pas d’intérêt dans une logique d’amélioration de laperformance et/ou de la durée de vie des accumulateurs Li-ion. De surcroit, certains typesd’impulsions ont été identifiés pour entrainer des effets préjudiciables à ces derniers. En seréférant à une application de véhicule industriel hybride électrique, nous avons évalué sur descritères techniques et économiques l’intérêt d’implémenter un système de stockage d’énergiecombiné, c'est-à-dire mutualisant l’usage d’une batterie Li-ion et desupercondensateurs/condensateurs. Il apparait que les stratégies consistant à agir sur lescomposantes hautes fréquences du signal pour ajouter/retirer des impulsions du profil vu parla batterie ne permettent pas d’accéder à des allongements de durée de vie qui pourraientcompenser le surcoût actuel lié à l’implémentation de ces systèmes. En outre, il apparait quele meilleur levier d’optimisation du bilan technique et économique associé au système destockage d’énergie est son dimensionnement. En effet, même si les systèmes de stockaged’énergie combinés utilisant les supercondensateurs permettent d’atteindre des réductions duratio coût/durée de vie considérables, la prise en compte globale des critères de coût, de duréede vie, de masse et d’encombrement s’avère plus favorable à la solution constituée d’unebatterie seule, de taille optimisée vis-à-vis de son applicationThis work aims to identify the possible impact of periodic current pulses on both performanceand lifetime of graphite/LiFePO4 secondary batteries. Contrary to the well-known results onlead-acid batteries and to results announced in previously published works, periodic pulses donot bring any benefit to the performance and the lifetime of Li-ion batteries. Moreover,certain pulse types have been identified to be detrimental to Li-ion batteries. Using the hybridelectric vehicle application as a reference, we evaluated both the technical and economicalaspects of implementing combined energy storage systems composed with Li-ion batteriesand supercapacitors/capacitors. We found that the control strategies acting on high frequencyharmonics of the current signal to adding/retrieving pulses to the Li-ion battery profile doesnot prolong its life enough to compensate the extra cost of such system implementation.Furthermore, it seems that the best way to optimize the technico-economic balance of theenergy storage system is the sizing. Even if combined energy storage systems using Li-ionbatteries and supercapacitors enable to considerably increase the lifetime/cost ratio, a generalconsideration of the criteria cost, life, mass and volume is more favorable to a solution whereone single Li-ion battery is optimally sized for its application
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Unell, Fredrik. "Preparation for a Thermal Balance Test of the MIST student satellite." Thesis, KTH, Skolan för elektroteknik och datavetenskap (EECS), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-266106.
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The MIST project was founded in 2014 at KTH and has been worked on by roughly 100 students since.Thermal engineering has been an important part of the project from start and a thermal model has beendeveloped to predict ight conditions. The thermal model created by previous students has to be correlatedby performing a thermal balance test. This test is going to take place in a thermal vacuum chamberat KTH Albanova during the period November 2019 to February 2020. This thesis describes the process ofpreparation for a Thermal Balance Test for MIST. Included in the preparation of the test are; developingthe test specications and denition of ground support equipment needed for the Thermal Balance Testin order to successfully correlate the thermal model.To perform the test some of the equipment has to be replaced with replacement components. The batteryand the solar panels are two expensive and crucial systems for the mission and has been chosen to bereplaced with mass dummies. These mass dummies are used in the thesis both to keep the correct thermalcapacity and approximate the conductive properties. The solar panel dummy plates can be drilled into, tomake sure the cables for thermocouples and heaters can get inside the satellite. Heaters will be mountedon the satellite, both to create gradients across the satellite to be able to measure them, and to useas safety heaters to prevent the temperature to get to low and damage components. The heaters will bemounted on the battery replacement board, the solar panel replacement plates and the bottom cover plate.The thermocouples to be used in the test are already installed in the vacuum chamber, which are of TypeT class 1 with a temperature accuracy of 0:5 C. The chamber has 50 thermocouples installed where24 are planned to be used to measure gradients across interfaces to be able to correlate them with thethermal model.In this thesis the thermal model is simulated in the new vacuum chamber environment to investigatewhat temperatures can be expected in the test and nd components and interfaces of interest to placethermocouples on. The test will start from ambient temperature of 20 C, then change the temperatureof the chamber to 0 C, with a temperature ramp of 1.5 C/min. The chamber will stay at 0 C until thetemperature of the satellite has stabilized within the chosen stability criteria of 0.5 C over two hours. Thisset point is chosen to take measurements for the hot case. When measurements are made, the chamberwill go to -50 C and stabilize at that temperature to take temperature measurements for the cold case.The temperature gradients measured in both the hot and cold case will be used to correlate the thermalmodel with the physical model.MIST projektet grundades 2014 på KTH och har arbetats på av drygt 100 studenter sedan projektet startade. Termisk kontroll har sedan projektets start varit av hög vikt och en termisk modell har tagits fram för att förutse temperaturer i omloppsbana. Den termiska modellen skapad av tidigare studenter måste korreleras genom att utföra ett termiskt vakuumkammartest. Det testet kommer att genomföras i en vakuumkammare på KTH Albanova under perioden November 2019 till Februari 2020. Den här avhandlingen beskriver processen att ta fram ett termisk vakuumkammartest för att korrelera modellen.För att genomföra testet måste vissa komponenter bytas ut till ersättningskomponenter. Batteriet och solpanelerna är dyra och kritiska system för uppdraget och har valts att ersättas med ersättningskomponenter. Dessa ersättningskomponenter används i den här rapporten för att bebhålla korrekt termisk massa och approximera de konduktiva egenskaperna. Solpanelsersättningsplåtarna kan borras i för att lättare få in sladdar för termiska sensorer och värmare i satelliten. Värmare kommer att monteras på satelliten, både för att skapa en temperaturgradient över satelliten för att kunna mäta dessa, samt som säkerhetsvärmare för att undvika att temperaturen blir för låg och skada komponenter. Värmarna kommer att vara monterade på batteriersättnings komponenten, solpanelsplåtarna och på den undre täckplattan.De termiska sensorerna valda för detta test är av Typ T klass 1 med en noggrannhet på ±0.5 ◦C. Vakuumkammaren har 50 installerade termiska sensorer och 24 av dem är planerade att användas i testet för att mäta temperaturskillnader mellan komponenter för att kunna korrelera kopplingen mellan dem i den termiska modellen.I den här avhandlingen kommer den termiska modellen simuleras i den nya vakuumkammarmiljön för att undersöka vilka temperaturer som kan förväntas och hitta komponenter av intresse för att korrelera och placera termiska sensorer på. Testet kommer att starta på en rumstemperatur på 20 ◦C, sedan ändra temperaturen på kammaren till 0 ◦C, med en hastighet på 1.5 ◦C/min. Kammaren kommer att stanna på 0 ◦C tills att satelliten har stabiliserats med det valda stabilitets kriteriet att temperaturen inte får ändras med mer än 0.5 ◦C över två timmar. Denna temperatur är vald för att ta mätningar för det varma fallet. När mätningarna är gjorde kommer kammaren att gå ned till -50 ◦C och stabiliseras på den temperaturen för att ta mätningar för det kalla fallet. Temperaturgradienterna mätta i båda fallen kommer att användasför att korrelera den termiska modellen med den fysiska modellen.
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Andersson, Emil. "Online Metallurgical Mass Balance and Reconciliation." Thesis, Umeå universitet, Institutionen för fysik, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-185252.
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In mineral processing, one of the most important and versatile separation methods is flotation. Flotation utilizes the different surface properties of the valuable minerals in the ore to separate them from the less valuable gangue material in the ore. Crushed and ground ore is mixed with water and fed into flotation tanks. In the flotation tanks, the particles of valuable mineral are made hydrophobic. That way, they can be floated by attaching to air bubbles and gather on top of the flotation tank as froth. This froth, containing higher concentrations of valuable mineral, is recovered and then processed further. The flotation circuit is controlled and maintained using measurements on the mass flows and grades of different materials. Due to economical, practical, and technological limitations, these measurements are performed at a chosen number of points in the circuit and at discrete points in time. Poor measurement data can have devastating consequences if the operators are left with limited information and errors in the circuit remain undetected. The accuracy of the acquired measurements is improved by performing mass balance and reconciliation. Traditionally, mass balance uses the sum of the total mass flows and the average grades over long times to avoid including the internal mass of the circuit in the calculations. It is desirable to perform mass balance directly to allow for faster intervention if any failures occur in the circuit during the on-line process. This report describes an on-line dynamic approach towards mass balancing and reconciliation of the mass flows and grades in a flotation circuit. Here, physical models of the flotation circuit are used to construct mass balance constraints using interpolation and test functions and the mass balance problem is posed as an optimization problem. The optimization problem is to adjust the assay such that the residual, the difference between the measured and the adjusted assay, is minimized while maintaining mass balance. An implementation in MATLAB and tests on synthetic data show that the dynamic formulation of mass balance does adjust 'erroneous' measurements such that mass balance is fulfilled. Given this result, there are still important aspects of the implementation that have to be addressed. The model uses the unknown and cell specific parameters flotation rate and recovery. Thus, these must be found or properly modeled. This report proposes a possible model for flotation rate as well as a strategy to find the recovery. The requirements of accuracy and speed of the implementation are also discussed. Possible next steps of this project is to further confirm a time effective implementation using synthetic data. Consequently, the implementation can be adapted for natural data in order to verify correctness of models.I malmanrikning, är flotation en av de viktigaste och mest mångsidiga metoderna. Flotation utnyttjar de fysikaliska ytegenskaperna som partiklar av värdemineral har för att separera dessa från det mindre värdefulla gråberget i malmen. Krossad och mald malm blandas med vatten och matas in i flotationstankar. I flotationstankarna görs partiklarna av värdemineral hydrofobiska. På så vis kan de fästa sig vid luftbubblor och flyta till ytan och bilda ett skum. Detta skum samlas sedan ihop och behandlas vidare eftersom det innehåller en högre koncentration av värdemineral. Flotationskretsen styrs och underhålls med hjälp av mätningar av massflödena och halterna av de olika ämnena som finns i kretsen. På grund av ekonomiska, praktiska, och teknologiska hinder kan dessa mätningar bara göras på ett utvalt antal punkter i kretsen samt bara vid diskreta tillfällen. Felaktigt data kan ha förödande konsekvenser om operatörerna lämnas med begränsad information och processen fortlöper med oupptäckta fel. Mätsäkerheten kan förbättras med hjälp av massbalansering och haltjustering. Traditionellt görs massbalansering genom att summera den totala massan som löpt genom kretsen samt medelvärden av halterna över lång tid för att undvika att räkna in den interna massan i systemet. Det är önskvärt att utföra massbalansering direkt för att möjliggöra snabbare ingrepp ifall fel uppstår i kretsen under den fortlöpande processen. Denna rapport beskriver en dynamisk lösning för massbalansering och justering av massflöden och halter i en flotationskrets. Här används fysikaliska modeller av kretsen för att konstruera bivillkor för massbalans med hjälp utav interpolation och testfunktioner och massbalanseringsproblemet ställs upp som ett optimeringsproblem. Optimeringen sker genom att justera mätserien så att residualen, skillnaden mellan det uppmätta värdet och det justerade värdet, minimeras under uppfyllande av mass balans. En implementation i MATLAB och tester på syntetisk data visar att den dynamiska formuleringen av massbalans justerar de felaktiga mätvärdena så att massbalans uppfylls. Med det resultatet i åtanke, finns det fortfarande viktiga aspekter av implementationen som bör tas hänsyn till. Modellen använder de okända och cellspecifika parametrarna flotationshastighet och utbytet och dessa måste kunna bestämmas för att denna modell ska kunna användas. Ett förslag på modellering av flotationshastigheten föreslås i rapporten. Dessutom ges förslag på strategier att hitta utbytet. Kraven på noggrannhet och snabbhet diskuteras också. Möjliga nästa steg för projektet är att vidareutveckla en tidseffektiv implementation genom att använda syntetiska data. Därefter kan en implementation för naturligt data verifiera modellerna.
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Sagerfors, Jörgen. "Land-atmosphere exchange of CO₂, water and energy at a boreal minerotrophic mire /." Umeå : Dept. of Forest Ecology and Management, Swedish University of Agricultural Sciences, 2007. http://epsilon.slu.se/200704.pdf.
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Mat, Jusoh Hanapi. "Investigation of phenotypic characterisation, metabolic profile and energy balance in male KLF3 knockout mice." Thesis, The University of Sydney, 2014. http://hdl.handle.net/2123/12406.
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Obesity is a disease characterised by an excess of white adipose tissue (WAT) driven by increased energy intake and/or decreased energy expenditure. Despite intensive research, the mechanisms underlying energy balance and linking obesity with metabolic disorders are not well understood. The use of genetically modified animal models allows understanding of the involvement of specific genes, such as in fat formation and metabolic processes. This can be used to identify targets for prevention or treatment of obesity. Our laboratory has a particular interest in Krüppel-like factor 3 (KLF3), a transcription factor that is involved in the process of adipocyte maturation. The objective of this study was to investigate the role of KLF3 in energy homeostasis, glucose and lipid metabolism in vivo. For this purpose, Klf3-/- mice on an FVB/NJ strain were developed and bred in-house. Only male Klf3-/- mice were used for investigation, and they were fed a standard chow or lard-based high fat diet. Male Klf3-/- mice have reduced body weight on a chow diet, and were resistant to diet-induced weight gain on a high fat diet. The reduced body weight in Klf3-/- mice was not attributed to reduced food intake, increased energy expenditure or increased faecal energy excretion. Instead, the negative energy balance in Klf3-/- mice was, in part, due to increased glucosuria. Klf3-/- mice have improved glucose tolerance and were resistant to diet-induced glucose intolerance. Klf3-/- mice have increased plasma adipolin levels and increased gene expression associated with anti-inflammatory macrophages in epididymal fat, which may contribute to the improved glucose tolerance. Klf3-/- WAT ex vivo was found to have both increased lipolysis and lipogenesis, implying another potential means of energy loss via futile cycling. In conclusion, KLF3 may play important roles in energy homeostasis and metabolism, and could potentially be targeted for treatments of obesity and associated disorders.
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Kelemen, Julia C. "Effects of tree encroachment on the water balance of a Scottish raised mire : a lysimeter study." Thesis, University of Dundee, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.320593.
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Tanabe, Kazutaka. "Migration of splenic lymphocytes promotes liver fibrosis through modification of T helper cytokine balance in mice." Kyoto University, 2015. http://hdl.handle.net/2433/200488.
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McCoy, Kurt J. "Estimation of vertical infiltration into deep Pittsburgh coal mines of WV-PA a fluid mass balance approach /." Morgantown, W. Va. : [West Virginia University Libraries], 2002. https://etd.wvu.edu/etd/controller.jsp?moduleName=documentdata&jsp%5FetdId=2745.
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Thesis (M.S.)--West Virginia University, 2002.Title from document title page. Document formatted into pages; contains x, 150 p. : ill. (some col.), maps (some col.). Includes abstract. Includes bibliographical references (p. 87-90).
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Beletse, Yacob Ghebretinsae. "Modelling the soil water and salt balance of planted pastures irrigated with sodium sulphate rich mine effluent." Diss., Pretoria : [s.n.], 2004. http://upetd.up.ac.za/thesis/available/etd-01182005-083427.
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Aumasson, Stéphanie. "Ethnographie d'un vin de Balagne : perceptions, représentations et mises en scène." Paris 10, 2010. http://www.theses.fr/2010PA100178.
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Qu’est-ce qu’un « vin corse » ? A travers l’ethnographie de plusieurs domaines vitivinicoles de Balagne, l’objectif de cette recherche est de cerner l’évolution de cette viticulture sur le marché actuel, en l’abordant sous divers angles. En premier lieu, les systèmes de production, en traitant des pratiques culturales et des méthodes de vinification. Puis, par le biais de l’étude des mises en scène des acteurs du monde vitivinicole corse et du comportement des consommateurs. Ces analyses mettent en évidence les processus de construction des représentations de l’objet « vin corse », et permettent de comprendre quels facteurs influencent les consommateurs. Au bout du compte, il s’agit de déceler quels sont les processus élaborés par les vignerons corses pour créer une identité spécifique et distinctive à leur vin, de peser l’importance de chaque intervenant et d’identifier les critères de qualité sollicités à la fois par les producteurs et les consommateursWhat is a Corsican wine? How to define a Corsican wine ? What makes a Corsican wine? Through the ethnographic study of several vineyards located in the Balagne region, the aim of this research is to define the evolution off such winemaking on the current market, by looking at it under various angles. As a first step, emphasis has been put onto the production system of such wine, taking into consideration the cultural processes and winemaking methods. Then, throughout the study of the relationships and behaviours of the different actors of the Corsican winemaking as well as the ones of the customers. Theses analyses point out the conception process of the representations of the “Corsican Wine” as an object and explain which criteria influence the customers. The goal is to highlight the processes elaborated by the Corsican winemaking actors to create a specific and distinctive identity for their wines, to weight the importance of each actor involved in such processes, and identify the quality criteria requested by the producers as well as the customers
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Houbaert, Xander. "Behavioral and synaptic consequences following removal of the Il1rapl1 gene in mice, a model of intellectual disability." Thesis, Bordeaux, 2014. http://www.theses.fr/2014BORD0250/document.
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Les désordres intellectuels (DI) comprennent une collection hétérogène de désordresneurodéveloppementaux qui émergent pendant l’enfance. Ils ont une incidence de 1 à 3% dansla population et sont associés avec des déficits dans les fonctions mentales et adaptives. Denombreuses mutations ont été identifiées dans des gènes codant pour des protéines quiremplissent des fonctions biologiques très diverses dans le cerveau. Parmi ces protéines,certaines sont enrichies à la synapse, supposant que les déficits cognitifs associés aux DIpourraient être reliés à des déficits synaptiques. L’objectif scientifique de notre équipe et decomprendre le rôle de certaines protéines dans la fonction synaptique et la cognition enutilisant des souris génétiquement modifiées portant des mutations dans le gènecorrespondant. Je me suis concentré sur Il1rapl1, un gène codant pour la protéine Interleukinreceptor-accessory-protein-like-1. Des mutations ou micro-délétions dans ce gène sont liés audéveloppement de DI chez l’homme. Dans les neurones, Il1rapl1 code pour une protéinetransmembranaire qui serait impliquée dans la formation et/ou la stabilisation de synapsesexcitatrices. Les conséquences de l’absence d’IL1RAPL1 à des niveaux plus intégrés restaientpeu étudiées lors du début de ma thèse. J’ai utilisé une souris déficiente pour IL1RAPL1 (KO) afinde comprendre le lien entre les déficits comportementaux et la fonction synaptique. Pour cela,j’ai soumis des souris KO à des taches comportementales de peur conditionnée. J’ai ensuiteutilisé une combinaison d’approches in vitro, ex vivo et in vivo afin de caractériser la fonctionsynaptique dans les circuits neuronaux dédiés : l’amygdale latérale et basolatérale. Desenregistrements electrophysiologiques ont montré une dérégulation de la balance entre latransmission inhibitrice et excitatrice (I/E) dans l’amygdale de souris Il1rapl1 KO, causant ainsides déficits dans la capacité d’acquérir et d’exprimer la mémoire de peur conditionnée. Lacorrection de ce déficit synaptique in vivo par pharmacologie ou par optogénétique a permis derestaurer le comportement chez les souris KOIntellectual disability (ID) comprises a highly heterogeneous collection of neurodevelopmentaldisorders that arise during childhood. They have an incidence of 1-3% in the population withimpairments in mental and adaptive functions. While the etiologies of IDs are thought to bevery heterogeneous, a significant proportion of ID has genetic origins. Mutations in single IDgenes lead to dysfunctions in proteins that fulfill highly different biological functions in thebrain. Interestingly, ID-related proteins are often found enriched at synapses, suggesting thatcognitive impairments defining ID could be related to alterations of synaptic function. The maingoal of our research team is to understand the role of ID-related proteins in synaptic functionand cognition using mouse models bearing gene mutations associated to ID in humans. Myresearch focused on the study of Il1rapl1, a gene coding for the Interleukin-receptor-accessoryprotein-like-1 protein. Micro-deletions or point mutations in this gene are directly linked to thedevelopment of ID and autism spectrum disorder in humans. In neurons, Il1rapl1 encodes atrans-membrane protein and several in vitro experiments point to its important role in thedifferentiation and formation/stabilization of excitatory synapses trough interactions withpresynaptic, trans-synaptic or postsynaptic partners. However, the consequences of Il1rapl1deficiency at more integrated levels remains poorly understood. The principal objective of mythesis is to explore the link between synaptic deficits and behavioral impairments in Il1rapl1-deficient mice. To achieve that, wild-type and mutant animals were first submitted to fearlearning tasks. I then used a combination of in vivo, ex vivo and in vitro functional essays tocharacterize synaptic functions in behaviorally relevant neuronal circuits. Ultimately, ourworking hypothesis were challenged in vivo by pharmacological and optogenetic approaches tonormalize behavioral deficits in Il1rapl1 KO mice. Altogether my work demonstrates thatInhibitory/Excitatory imbalances associated with the absence of Il1rapl1 impaired both thecapacity to form new memories as well as the expression of previously formed memories
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Grubbs, John Keith. "Developing a strategic plan for balanced missions involvement at Midway Baptist Church, Meridian, Mississippi." Theological Research Exchange Network (TREN), 2003. http://www.tren.com.
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Abegunde, Oluseyi Ayokunle. "Geologic and geological assessment of Acid Mine Drainage and heavy metals contamination in the West Rand, Witwatersrand Basin, South Africa." University of the Western Cape, 2015. http://hdl.handle.net/11394/4785.
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Masters of ScienceOver the years, South Africa has produced over 468 million tons of mine waste yearly, in which gold mining waste accounted for 221 million tons (47%) of all mine waste produced, making it the largest, single source of waste and pollution. The exposure of these mine wastes such as tailings dams, waste rocks to oxidation and leaching has been the source of heavy metal release into the environment. This study assessed the magnitude of possibly leachable metals, its distribution and associations and predicted the AMD load discharge over time, from Mogale’s tailings dam into the environs in Randfontein area, Witwatersrand Basin, South Africa. Fifty-one tailings dam samples were analysed for their mineral and multi-elements contents. Petrography studies was done by X-Ray Diffraction (XRD) technique to determine the mineralogical composition. X-ray fluorescence (XRF) and Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) techniques were used to determine the multi-elements content in the tailings dam samples. The dataset were evaluated using multivariate statistics, Geographical Information Systems (GIS) and geochemical mass balance techniques. From the results, the tailings dam lithology was grouped into four distinct layers. The uppermost oxidized layer is siliceous and contains the highest SiO2 (87.32%) contents, which is with the lowest contents in Tot/S, U, As, Zn, Ni, Co, and Cu. A downward decrease in SiO2 (76.39%) contents occurs, coupled by an increase in Fe2O3, Tot/S, U, As, Zn, Ni, Co, and Cu, reaching maximum contents in layer 3. Layer 4 is the least weathered horizon. The cluster analysis grouped the samples into four sub-clusters based on the variation in SiO2 and Al2O3 contents. Factor analysis (83.542% total data variance) related the four controlling factors of element distribution to the occurrence in ore elements (sulphides), silicates, mining additives and refractory minerals. Elements of the same origin show a similar concentration trend down hole in the GIS interpolation analysis. The geochemical mass balance showed variable gain and loss of oxides and trace elements within each layer. Based on the variation patterns of the Tot/S contents and other mobile elements, about 0.164kg/tonne/yr(±0.02) of the tailings materials are leached yearly. Layer 1 is the most altered. This assessment and prediction study therefore gives an insight to the geochemical behaviour of an abandoned tailings dam, highlighting its extent of oxidation. However, the interaction between the oxidized zone and transition zone should be given more attention, to determine the actual extent of damage.
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Madhu, Malav Navinchandra. "Impact of Diabetes on ACE/ACE2 Balance and Angiotensin II Type 1 Receptor Expression in db/db Diabetic Mice." Wright State University / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=wright1253301307.
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Guedes, Glaucevane da Silva. "Estudo hepático de um modelo murino dietético para síndrome metabólica: perfil morfológico, funcional e balanço redox." Universidade Federal de Alagoas, 2009. http://repositorio.ufal.br/handle/riufal/635.
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Changes in lifestyle of people has been dynamically observed in recent
decades, emphasis is given to dietary issues. In this case, as directly responsible for chronic
diseases, along with other aspects of lifestyle such as inactivity, smoking, quality of life. In
the context of chronic diseases of high incidence and prevalence, the metabolic syndrome has
gained prominence in clinical and experimental research in the search for early diagnostic
methods for its various components such as the vascular, biochemical and liver, all also
associated with diet. In this context, there was the inclusion of non-alcoholic fatty liver
disease as liver component of the metabolic syndrome, which is the central object of this
work. Objective: To evaluate the profile morphological, functional and redox balance in the
liver of a novel induced-diet mice model for metabolic syndrome. Methods: Eleven isogenic
male C57BL/6J mice were randomly divided into control (CT) and hypercaloric (HC) groups
and fed with chow and hypercaloric diet, respectively, for 26 weeks. We did ratings serum
markers of liver function (ALT, AST, ALP, γ-GT, LDH, albumin and total protein), analysis
of local redox status (SOD, CAT and lipid peroxidation) and histological study of tissue.
Results: There were significant elevations of the statistical point of view in the main markers
of liver function in HC animals. This increase was approximately 1.5 times for ALT, 2.5 for
AST and 7.4 for ALP. The activity of γ-GT followed the pattern of significant increase in the
HC group, despite its low activity. There re no differences in the concentrations of albumin
and total protein. On the local redox state, the activity of SOD was not different between
groups, the catalase activity was significantly decreased in HC group and there re high levels
of peroxidation in this same group. The histological findings corroborate these results, which
corresponds to advanced liver disease in animals HC (default cirrhotic). Conclusion: The
hepatic component in the novel induced-diet mice model for metabolic syndrome shows changes in your profile functional, redox balance and morphological.
Keywords: Metabolic Syndrome, Liver Functions, Redox Balance, Novel Diet-induced Mice
Model.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
As alterações no estilo de vida das pessoas vem sendo dinamicamente observadas nas últimas décadas; destaque especial é dado aos aspectos dietéticos. Neste caso, como responsável direto por doenças crônicas, juntamente com outros aspectos do estilo de vida como sedentarismo, tabagismo, qualidade de vida. No contexto das doenças crônicas de elevada incidência e prevalência, a síndrome metabólica vem ganhando destaque nas pesquisas experimentais e clínicas na busca de métodos diagnósticos precoces para seus vários componentes a exemplo dos vasculares, bioquímicos e hepáticos, todos com associação também dietética. Neste contexto, destaca-se a inserção das doenças hepáticas gordurosas não alcoólicas como componente hepático da síndrome, sendo este o objeto central do presente trabalho. Objetivo: Avaliar o perfil morfológico, funcional e o balanço redox do fígado de um novo modelo murino dietético para síndrome metabólica. Métodos: Onze camundongos isogênicos machos C57BL/6J foram randomicamente divididos nos grupos Controle (CT) e Hipercalórico (HC) e alimentados com dieta chow e hipercalórica, respectivamente, durante 26 semanas. Foram procedidas avaliações plasmáticas de marcadores de função hepática (ALT, AST, ALP, γ-GT, LDH, albumina e proteínas totais), análise do estado redox local (SOD, CAT e peroxidação lipídica) e estudo histológico do tecido. Resultados: Foram encontradas elevações significativas do ponto de vista estatístico nos principais marcadores de função hepática nos animais HC. Esse aumento foi de aproximadamente 1,5 vezes para ALT, 2,5 para AST e de 7,4 para ALP. A atividade de γ-GT seguiu o padrão observado de elevação significativa no grupo HC, apesar de sua baixa atividade. Não foram observadas diferenças nas concentrações de albumina e proteínas totais. Relativo ao estado redox local, a atividade de SOD não foi diferente entre os grupos, a de catalase foi significativamente diminuída nos HC e os níveis de peroxidação elevados. Os achados histológicos corroboram esses resultados, sendo corresponde a doença hepática avançada nos animais HC (padrão cirrótico). Conclusão: O componente hepático no novo modelo murino dietético para síndrome metabólica estudado apresenta alterações em seu perfil morfológico, funcional e no balanço redox.
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Liu, Zhuhuan, and Chen Zhou. "Hydrological and chloride transport processes in a small catchment of the Norrström Basin : a MIKE SHE modelling approach." Thesis, KTH, Hållbar utveckling, miljövetenskap och teknik, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-250030.
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Water is ubiquitous on our planet and constitutes a vital part of ecosystems. It supports the life of all beings on the earth while simultaneously evokes water-related issues such as water shortage, water contamination. As UN advocates, a globally shared blueprint for available clean water is depicted in Sustainable Development Goals (SDGs). However, there still exists a gap between current water management situations and our sustainable goals Modelling based on Hydro-Meteorological Data provides a way to understand regional hydrological processes and monitor environmental chemistry changes, especially for anthropogenic pollution. Furthermore, hydrological models make it possible to predict changes in water quantity and quality, under the context of climate change. The study area of this project is located in the Kringlan catchment, Norrström basins, occupying an area of 54.5 km2. The local discharges merge into Rastälven river and flow to the east, eventually discharging into the Baltic Sea. This project builds up a water balance model based on the meteorological data in the time frame from 2011 to 2012. The water balance model is calibrated to accurately simulate realistic hydrological components interactions, during each process, various parameters have been tested and adjusted to improve model robustness. Meanwhile, the project tries to strike a balance between the complexity of the model and amount of time it takes to run the model. The calibrated model is also validated to ensure model performance using statistical analysis. Additionally, a particle tracking model for the saturated zone is developed on the basis of the water balance model. Chloride is chosen as the trace element due to its feature of unreactive in ecological systems. The model results could also provide a value to groundwater age estimation. Suggested by previous researches targeting the area, leakage from vegetation and forest soil in this catchment have contributed to imbalances in local Cl- budgets. An internal source of chloride from soil leaching is specified in the model at the same time with an external source from stream discharge. The coupled modelling through the application of MIKE SHE software and calibration process help us to understand dynamic processes of hydrological modelling and chloride particle transport in the Kringlan catchment. A future improvement to consider is extending the current model boundary to a larger area and introducing more reference data. It is also possible to establish a fully integrated solute transport model to investigate Chloride transport in the catchment.Vatten ersätter en viktig del av ekosystemet men det framkallar vattenrelaterade problem som vattenbrist och vattenförorening samtidigt. Emellertid finns det fortfarande ett gap mellan nuvarande vattenhanteringssituationer och våra hållbara mål. Modellering baserad på meteorologiska data erbjuder en möjlighet att förstå regionala hydrologiska processer och övervaka förändringar av miljömässiga kemikalier, särskilt för antropogena föroreningar. Dessutom finns det en hög potential för att förutse förändringar i vattenmängd och kvalitet med hydrologiska modeller, i samband med klimatförändringar. Studieområdet ligger i Kringlans upptagningsområde som ett av Norrström basins, med en yta på 54,5 km2. De lokala utsläppen sammanfogas i Rastälven och strömmar österut, så småningom mynnar i Östersjön. Detta projekt bygger upp en vattenbalansmodell baserad på meteorologiska data inom tidsramen från 2011 till 2012. Vattenbalansmodellen är kalibrerad för att exakt simulera realistiska hydrologiska komponentinteraktioner. För att förbättra modellens robusthet har olika parametrar testats och anpassats under varje process. Samtidigt försöker projektet att hitta en balans mellan modellens komplexitet och hur lång tid det tar att driva modellen. En partikelspårningsmodell för den mättade zonen har utvecklats med utgångspunkt i vattenbalansmodellen. Klorid används som spårämne eftersom det är inert i ekologiska system. Modellsresultaten kan också ge ett värde för grundvattenberäkningen. Tidigare undersökningar inriktade på området föreslår att läckage från vegetation och skogsmark i detta avrinningsområde har bidragit till obalanser i lokala Cl- budgetar. Med hjälp av MIKE SHE modellen har vi undersökt dynamisk process för hydrologisk modellering och kloridpartikelspårning i Kringlan avrinningsområde. Vad som kan gör i framtiden är att förlänga den nuvarande modellgränsen till ett större område med mer referensdata. Det är också möjligt att upprätta en fullständigt integrerad lösningsmodell för att undersöka kloridtransporter i ett avrinningsområde.
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Videll, Ebba. "Survey of sulphates in process water of LKAB - Kiruna operation." Thesis, Luleå tekniska universitet, Industriell miljö- och processteknik, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-76411.
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Sulphate-rich wastewater is an increasing concern for industries as LKAB. The water chemistry of the LKAB Kiruna water system is characterized by high alkalinity, high pH (pH 7.5-9.0) and high concentrations of chemical species and soluble minerals. The sulphate content in the water system of Kiruna is associated with the dissolution of calcium sulphate as anhydrite (CaSO4) and gypsum (CaSO4 2H2O). However, the high concentrations of sulphate in the effluents from the LKAB Kiruna operation are unique for iron ore mining. The aim of the thesis was to study and evaluate the behavior of sulphate in the process water system of the Kiruna concentrator plants. This was done by laboratory grinding (leaching tests), equilibrium calculations with the HSC software and mass balancing of the concentrator KA3 in Kiruna. The highest concentrations of sulphate have been detected in the process water of KA3, hence the focus has been on KA3 regarding sampling, evaluation and comparison. Water treatment technologies for sulphate and the effect of process water on ore processing have not been included in this project. The laboratory grinding was done using process water and ore from the concentrator KA3. During the experimental work with laboratory grinding the parameters pH, temperature and operating times for primary- and secondary grinding, respectively, were varied. The observations from the experimental work were further confirmed by equilibrium calculations and mass balancing. The following conclusions were drawn. Anhydrite/gypsum is not leached from the ore during ore processing with process water having concentrations of sulphate already close to the saturation point at approximately 1800 mg/L. If the process water is diluted with water with lower sulphate content, e.g. mine water or a diluted return water from the pond system (e.g. during spring flood), anhydrite/gypsum in ore will be dissolved until the sulphate concentration reaches the saturation point. The ionic strength of the process water controls the saturation point and thus the sulphate concentration. Leaching of anhydrite/gypsum in saturated process water, with respect to sulphate, is not affected by grinding time or adjusted conditions in the process water, such as temperature or pH value. For further work, it is recommended to investigate the behavior of sulphate in the tailings pond system to increase knowledge of the overall behavior in the water system. In addition, a similar investigation of the behavior of uranium in the process water is recommended in order to face future environmental standards.
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Silva, Patrícia Tachinardi Andrade. "To be diurnal or nocturnal: the interplay of energy balance and time of activity in subterranean rodents (Ctenomys aff. knighti) and laboratory mice (Mus musculus)." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/41/41135/tde-25072017-110626/.
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Studies that show discrepancy between nocturnal and diurnal activity under laboratory and field conditions, respectively, have become increasingly common in rodents and suggest that the definition of temporal niche is far more plastic than originally suspected. Recently, it has been proposed that factors that challenge the animal\'s energy balance play an important role in temporal niche switches. Food availability and environmental temperatures could then be one of the fundamental differences between field and laboratory that could alter the temporal daily pattern of activity. In laboratory, animals are fed ad libitum, while in nature they need to expend energy for foraging. The \"circadian thermo-energetics hypothesis\" suggests that daytime activity could be a response to the high energetic costs of foraging, allowing the animal to save energy during the cooler night hours by resting and taking shelter in burrows where temperatures are higher than on the surface. In this thesis, we explored the interplay of plasticity in nocturnal/diurnal activity definition and energetic metabolism in two rodent species, tuco-tucos (Ctenomys aff. knighti) and laboratory mice (Mus musculus). Tuco-tucos are subterranean rodents which face peculiar energetic challenges in their habitat and were shown to be diurnal in the field and nocturnal in the laboratory. We characterized how their energy expenditure varies across day and night and described the peculiar finding of some factor inside the metabolic chamber being itself a trigger for the nocturnal to diurnal switch. Moreover, we estimated the amount of energy tuco-tucos would save by being diurnal in the field, by combining metabolic rate measurements at various ambient temperatures with records of environmental temperature in the tuco-tuco\'s natural habitat. We also described further investigations of circadian plasticity in both locomotor activity and body temperature of laboratory mice subjected to food restriction in semi-natural conditions. The findings of these three studies provided valuable evidence for the discussion of the role of environmental factors, particularly energetic challenges, in the plasticity of daily rhythmsEstudos que apontam discrepâncias entre atividade noturna e diurna, respectivamente, sob condições de laboratório e de campo, estão cada vez mais comuns em roedores e sugerem que a definição de nicho temporal é muito mais plástica do que se suspeitava inicialmente. Recentemente, foi proposto que fatores que desafiam o balanço energético do animal desempenham um papel importante em mudanças de nicho temporal. A disponibilidade de alimento e as temperaturas ambientais poderiam ser algumas das diferenças fundamentais entre campo e laboratório, os quais poderiam alterar o padrão temporal de atividade diária. No laboratório, os animais são alimentados ad libitum, enquanto na natureza eles precisam gastar energia para forrageamento. A \"hipótese circadiana termoenergética\" sugere que a atividade diurna pode ser uma resposta aos altos custos energéticos do forrageamento, permitindo que o animal economize energia durante as horas mais frias da noite, descansando e se abrigando em tocas onde as temperaturas são mais altas do que na superfície. Nesta tese, exploramos a interação entre a plasticidade da definição noturnalidade/diurnalidade e o metabolismo energético em duas espécies de roedores, o tuco-tucos (Ctenomys aff. knighti) e o camundongo de laboratório (Mus musculus). Tuco-tucos são roedores subterrâneos que enfrentam desafios energéticos peculiares em seu habitat e verificamos que são diurnos em campo e noturnos em laboratório. Nós caracterizamos a variação de seu gasto energético ao longo do dia e da noite e descrevemos o achado peculiar de que algum fator presente no interior da câmara metabólica pode ser um gatilho para a mudança de noturnalidade para diurnalidade. Além disso, estimamos a quantidade de energia que os tuco-tucos economizariam ao serem diurnos em campo, combinando medidas de taxa metabólica em várias temperaturas ambientes com registros dessa temperatura no habitat natural do tuco-tuco. Descrevemos também investigações adicionais sobre a plasticidade circadiana na atividade locomotora e na temperatura corporal de camundongos submetidos à restrição alimentar, em condições seminaturais. Os achados desses três estudos forneceram evidências valiosas para a discussão do papel dos fatores ambientais, particularmente os desafios energéticos, na plasticidade dos ritmos diários
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Krohn, Jeremy P. "PERFORMANCE ANALYSIS OF A SUCCESSIVE ALKALINITY PRODUCING SYSTEM TREATING ACID MINE DRAINAGE AT SIMMONS RUN IN COSHOCTON COUNTY, OHIO." Ohio University / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1173151741.
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Andrade, Arriagada Felipe Alejandro. "Diseño de sistema de control de gestión para la Corporación Construyendo Mis Sueños." Tesis, Universidad de Chile, 2018. http://repositorio.uchile.cl/handle/2250/168601.
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Memoria para optar al título de Ingeniero Civil IndustrialLa Corporación Construyendo Mis Sueños (CMS), es una organización sin fines de lucro, encargada de dar apoyo a emprendedores y empresas de menor tamaño, mediante asesoría y proyectos, con el objetivo de contribuir de manera sostenible a su crecimiento. Uno de los proyectos que CMS lleva a cabo, es la operación de Centros de Desarrollo de Negocio (CDN) de Sercotec. La operación de estos centros es licitada públicamente por un periodo de cinco años y evaluada de forma anual, en base al cumplimiento del convenio de operación. CMS se ha adjudicado cuatro Centros en la región Metropolitana: CDN San Bernardo, CDN Estación Central, CDN Maipú y CDN Las Condes. La propuesta de Diseño. surge a partir del interés de la Dirección Ejecutiva de generar las herramientas de control de gestión, para lograr reconocimiento y excelencia, para mantener la asignación como operadores de CDN, principal ingreso de CMS. Esto, ha significado autonomía administrativa y financiera y la posibilidad de seguir desarrollando programas, que apoyen emprendimientos en el sector de la micro y pequeña empresa. Por otro lado, se requiere el uso de instrumentos y modelos de la Ingeniería que permita proyectar su estrategia en un cambio en la gestión del CMS. Para lograr lo anteriormente descrito, se ha diseñado un sistema de control de gestión, siguiendo la metodología de Balanced Scorecard propuesta por Kaplan y Norton. El trabajo metodológico consiste en un diagnóstico exploratorio, donde se analiza a CMS en base a sus propios antecedentes e información de microempresas relacionadas. También se consulta a un panel de expertos, lo que nos permite tener un estudio sobre los factores internos y externos. Posteriormente, siguiendo los lineamientos de la misión y visión de CMS, focalizamos la información del mapa estratégico en tres temas, que apuntan principalmente a la búsqueda de mayor calidad en los CDN con menor cantidad de recursos -eficiencia operativa-; de atraer, retener y fortalecer clientes que sustente el modelo implementado por la corporación -crecimiento rentable sostenido-; y cuidar el capital humano por medio de crecimiento constante y mantención de un buen clima laboral -capacidades organizacionales-. Finalmente, se elabora el sistema de control de gestión, formulando 19 indicadores de gestión para los 13 objetivos estratégicos. Las metas son fijadas para controlar el cumplimiento, así como también se asigna un responsable de cada uno de los indicadores. Se espera como resultado de lo propuesto en esta memoria, un cambio en la estructura y los procesos de CMS, para lograr una mejora sustancial en sus objetivos. El impacto de esta herramienta permite enfrentar el crecimiento organizacional midiendo el rendimiento de los centros de forma periódica, y así tomar acción para el cumplimiento de su estrategia.
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Yu, Bo Nancy. "Corticotropin releasing factor (CRF) and leptin contributions to energy balance in genetically obese (lep-ob/lep-ob) mice, possible involvement of CRF in the leptin effects." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0002/NQ41634.pdf.
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Kellner, Erik. "Surface Energy Exchange and Hydrology of a Poor Sphagnum Mire." Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2001. http://publications.uu.se/theses/91-554-5121-7/.
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Legeay, Étienne. "Géodynamique du bassin de Sivas (Turquie) : de la fermeture d’un domaine océanique à la mise en place d’un avant-pays salifère." Thesis, Pau, 2017. http://www.theses.fr/2017PAUU3019/document.
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L’Anatolie fait partie d’un vaste domaine orogénique qui s’étend des Alpes à l’Himalaya. Les sutures ophiolitiques rencontrées marquent les cicatrices de plusieurs domaines océaniques (branches de la Néotéthys Nord), interdigités entre plusieurs blocs crustaux au cours du Mésozoïque. La fermeture de ces domaines au Crétacé supérieur est accompagnée de la mise en place de bassins tertiaires syn-orogéniques dont fait partie le Bassin de Sivas, limité au nord par le bloc du Kırşehir et au Sud par les Taurides. Une étude structurale de terrain, complétée d’analyses géochimiques, biostratigraphiques et thermochronologiques ainsi que l’étude de 700 km de lignes sismiques 2D inédites, a été menée pour tenter de comprendre (i) le contexte géodynamique régional et (ii) l’architecture tectono-sédimentaire de ce bassin.L’étude des ophiolites présentes le long de la bordure sud du Bassin de Sivas met en évidence des péridotites intensément serpentinisées. La partie supérieure de l’ophiolite présente des brèches et ophicalcites caractéristiques de l’exhumation mantellique, alors que l’analyse géochimique des corps magmatiques révèle un environnement de supra-subduction, daté à circa 90 Ma (U-Pb sur zircon). Ces analyses démontrent la présence d’un domaine océanique embryonnaire entre le Kırşehir et les Taurides, dont la fermeture s’initie le long d’ancienne failles de détachement. L’obduction de la nappe de péridotite et de son mélange frontal sur la marge Nord des Taurides entre le Turonien et le Maastrichtien, permet de former le « socle ophiolitique » commun aux bassins est-anatoliens. L’analyse détaillée de la partie centrale du bassin, en carte et à l’aide de lignes sismiques 2D inédites et de thermochronologie basse température [AFTA et (U-Th)/sur apatite], a permis de proposer un modèle d’évolution cinématique sur la base de coupes équilibrées. La propagation de la déformation vers le Nord, initiée dès l’Eocène inférieur, permet l’isolation progressive du bassin et une forte accumulation d’évaporites à l’Eocène supérieur. Les dépôts de l’Oligo-miocène sont ensuite contrôlés par l’halocinèse, permettant la mise en place de deux générations de mini-bassins salifère, séparés d’une canopée. Les géométries dans le domaine halocinétique, et les variations latérales dans le bassin, montrent le contrôle exercé par (i) le bassin pré-évaporite affleurant le long de la moitié sud du bassin et (ii) l’épaisseur du niveau de sel initial.L’intégration de ces observations à l’échelle régionale met en évidence un contrôle du raccourcissement crustal, dans les Taurides et les bassins tertiaires, lié à la fermeture de la Néotéthys Sud, en générant l’émergence de structures de socles. La collision enregistrée à l’Oligocène supérieur - Miocène lors de l’indentation de la plaque Arabe le long des Taurides est contemporaine de la déformation du Bassin de Sivas et des bassins adjacentsAnatolia is part of a vast orogenic domain that extends from the Alps to the Himalayas. Numerous ophiolitic sutures defined the remnants of several oceanic domains (Northern and southern Neotethys), between continental fragments formed during Mesozoic time. Oceanic closure during Late Cretaceous is recorded by the establishment of syn-orogenic tertiary basins, including the Sivas Basin bounded to the north by the Kırşehir block and to the south by the Taurides. An extended study based on field and completed by geochemistry, biostratigraphy and thermochronology analyzes and more than 700 km unpublished seismic data, was conducted to resolve (i) the regional geodynamic context and (ii) the tectono-sedimentary architecture of this basin.The ophiolites located along the southern edge of the Sivas Basin are made of serpentinized peridotites. The upper part of the ophiolite present breccias and ophicalcites commonly described as associated to mantle exhumation environment, while the geochemical analysis of the magmatic bodies reveals a supra-subduction environment dated at circa 90 Ma (U-Pb on zircon). These observations are in agreement with an embryonic ocean domain located between the Kırşehir and the Taurides, the closure which was initiated along fossil detachment faults. The obduction of the peridotite nappe and its frontal mélange on the northern margin of the Taurides between the Turonian and the Maastrichtian allows forming the “ophiolitic basement” of the east-anatolian basins.A detailed map and cross-section analysis, supported by 2D seismic lines and low-temperature thermochronology [AFTA and (U-Th) / on apatite], resulted in a kinematic evolution model and the realization of balanced cross-sections. The propagation of the deformation towards the north, initiated in the Lower Eocene, results in the progressive isolation of the basin and a strong accumulation of evaporites during the Upper Eocene. The Oligo-Miocene depocenters were controlled by halokinesis, forming two generations of mini-basins, separated by a salt canopy. The geometries in the halokinetic domain and the lateral variations in the basin show the control exerted by (i) the pre-evaporite basin outcropping along the southern half of the basin and (ii) the thickness of the initial salt level.Integration at the regional scale within the Taurides highlights the propagation of crustal shortening related to the Southern Neotethys closure, which formed linear tectonic basement exhumation. The collision recorded in the Upper Oligocene - Miocene during the indentation of the Arabic plate along the Taurides is contemporaneous to the deformation the Sivas Basin
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Acremont, Quentin d'. "Étude des propriétés thermiques de librairies d’alliages ternaires en couches minces et mise en évidence du transport non-diffusif par spectroscopie thermique pompe-sonde femtoseconde." Thesis, Bordeaux, 2017. http://www.theses.fr/2017BORD0665/document.
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Durant ces travaux, nous nous sommes intéressés à l’étude des transferts thermiques aux nano-échelles dans les couches minces par spectroscopie pompe-sonde femtoseconde. Dans un premier temps, nous nous sommes intéressés à la mesure haute-cadence de la conductivité thermique d’alliages de Fe-Si-Ge et Ti-Ni-Sn, dans le but d’optimiser leur processus de fabrication et de créer une base de données des propriétés thermiques de ces matériaux. Afin de pouvoir mesurer une grande quantité d’échantillons en un temps réduit, un système de mesure haute cadence entièrement automatisé a été développé et utilisé avec succès. Dans un second temps,ces travaux ont portés sur l’étude du transport thermique dans trois matériaux (Ge, GaAs In-GaAs) par spectroscopie pompe-sonde femtoseconde. Une nouvelle méthode de mesure de la réponse spectrale des nanomatériaux sur une gamme de fréquences allant de quelques centaines de kHz jusqu’au THz a été développée. Les mesures à l’aide de cette méthode ont permis de confirmer la présence d’un régime de transport qualifié de quasi-balistique dans certains matériaux,et une méthode d’extraction de propriétés thermiques à partir de la réponse spectrale mesurée, et prenant en compte ces effets quasi-balistiques, a été développée. L’ensemble des résultats obtenus par ces nouvelles méthodes confirment les travaux précédents décrits dans la littérature. Enfin, la mesure de la réponse spectrale d’un nano-matériau à haute fréquence est en grande partie limitée par la gigue des cavités lasers utilisées par l’expérience. Ainsi, la dernière étape a été de développer un système de mesure de cette gigue et de synchronisation de cavités laser qui pourra permettre de repousser la limite des fréquences mesurables par spectroscopie pompe-sonde femtosecondeIn this work, we studied ultrafast thermal transport at nanoscale in thin films by femtosecond pump-probe thermal spectroscopy. We first developed a high-throughput heterodyne thermoreflectance setup that allows the extraction of thermal properties of a large number of sample in a minimum time, aiming at creating a database of these properties for a large numberof thin film ternary alloys with thermoelectric potential. In the second part of this work, wefocused on the study of thermal transport in three materials : Ge, GaAs and InGaAs. A high resolution phonon spectroscopy setup, along with a spectral reconstruction method allowed usto measure the response of these materials up to several tens of GHz in Fourier domain, which highlighted the presence of non-diffusive thermal transport in InGaAs. Non-diffusive theory,based on Lévy dynamics, allowed us to model this superdiffusion phenomenon and to extract coherent, frequency-independant thermal properties of these materials. Also, high frequency(>GHz) measurements of these spectral responses have shown interesting effects related to the ultrafast thermalisation in transducer-like very thin films. Finally, high-frequency thermal spectroscopy is inherently limited by the intrinsic timing jitter of laser cavities. Thus, the last partof this work was dedicated to developing a timing jitter measurement and active laser synchronisation system in order to increase the signal-to-noise ratio and access higher frequencies in pump-probe thermal spectroscopy experiments
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Rezgui, Cyrine. "Etude du potentiel d'introduction de la culture du pois d'hiver dans les successions culturales en Normandie : conséquences sur les communautés microbiennes du sol et les flux d'azote Impacts of the winter pea crop (instead of rapeseed) on soil microbial communities, nitrogen balance and wheat yield Quantification et analyse des exsudats racinaires de pois, de blé et de colza : mise au point d’une méthodologie de collecte des exsudats racinaires N rhizodeposition quantification and root exudates characterization of pea (Pisum Sativum L.), rapeseed (Brassica napus L.) and wheat (Triticum aestivum L.) under controlled conditions Linking soil microbial community to C and N dynamics during crop residues decomposition." Thesis, Normandie, 2020. http://www.theses.fr/2020NORMR047.
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La transition agroécologique vise la triple performance agronomique, écologique et sociétale des exploitations agricoles. Un certain nombre de pratiques agricoles permet d’envisager la construction et le développement de systèmes de culture répondant à ces contraintes. Les légumineuses, par leur capacité à fixer l’azote atmosphérique, sont une alternative intéressante aux intrants azotés. Outre l’absence de fertilisation lors de leur culture, elles fournissent de l’azote à la culture suivante. Il existe cependant un manque de références sur certaines légumineuses à graines et notamment la culture du pois d’hiver. En effet, si des données acquises dans différentes régions françaises sont disponibles, aucune référence n’a été publiée pour la Normandie où la culture du pois d’hiver connaît un récent regain d’intérêt. Cette thèse propose d’évaluer, sur une période de deux ans, l’effet du remplacement du colza par le pois d’hiver en tête de rotation en réalisant une analyse comparative de ces deux successions (pois d’hiver-blé et colza-blé). L’objectif était d’évaluer l’effet de ce changement de tête de rotation (pois d’hiver vs colza) sur l’état biologique du sol et les flux d’azote à différentes échelles spatiotemporelles. Les résultats ont révélé une forte variabilité spatio-temporelle dans la réponse des communautés microbiennes du sol, et mis en évidence l’importance du contexte pédoclimatique dans le déterminisme de l’abondance et de l’activité des communautés microbiennes du sol. Ils ont montré par ailleurs, l’effet positif du pois d’hiver sur la disponibilité de l’azote minéral au cours du cycle cultural et pour les cultures suivantes, ici le blé puis l’orge. Les apports d’azote minéral dans le sol lié à la contribution des parties racinaires via la rhizodéposition et à la dégradation des résidus de culture après récolte ont été évalués au cours de ce travail de thèse. En effet, si la rhizodéposition s’est révélée plus importante sous pois d’hiver, elle n’a pas eu d’impact significatif sur les communautés microbiennes rhizosphériques. Contrairement à ces observations, la dégradation des résidus de culture a significativement modifié la composition des communautés bactériennes en lien avec leur composition biochimique initiale. La succession culturale incluant le pois a enrichi le sol en azote minéral mais des risques de perte d’azote par lixiviation de l’ordre de 23 kg N. ha-1 ont été estimés. Ces constats soulignent l’importance d’adapter la conduite des systèmes de culture incluant le pois d’hiver, en limitant les pertes d’azote par lixiviation et en maximisant son utilisation par les cultures suivantes. Les résultats de ces travaux ont confirmé la diminution des quantités d’engrais azoté utilisées dans la succession contenant le pois, sans préjudice de productivité, ni pour le pois, ni pour la culture suivante, ici, le blé. Finalement, introduire le pois d’hiver dans la rotation de culture en région Normandie, semble permettre de répondre à la problématique d’augmentation du coût des intrants, et aux enjeux de transition agroécologique et d’autonomie protéique régionaleThe agroecological transition targets triple agronomic, ecological, and societal performance of farms. Some new agricultural practices had emerged to develop a new cropping system to respond to these constraints. Legumes constitute an interesting alternative. Indeed, legumes are advantageous for soils due to their symbiotic relationship with nitrogen-fixing bacteria. The presence of compatible rhizobia combined to nitrogen-limited conditions promotes symbiosis which is the most efficient way for legumes to acquire more nitrogen. Compared with non-nodulated plants, symbiosis provides a competitive advantage by increasing soil nitrogen pool. However, some grain legumes, notably winter pea, are rarely studied, especially in the Normandy region where no reference has been published for this crop. The objective of this study is to compare two crop successions for a period of two years (winter pea-wheat and rapeseed-wheat), in order to assess the effect of replacing rapeseed by winter pea at the head of the rotation .We evaluated the effect of these two crops (winter pea vs rapeseed) on the biological state of the soil and nitrogen fluxes at different spatio-temporal scales. The results showed a significant spatio-temporal effect on the response of soil microbial communities and highlighted the importance of the pedoclimatic context in determining the abundance and activity of soil microbial communities. A positive effect of winter pea has been demonstrated on the availability of mineral nitrogen during the crop cycle and for following crops (wheat and barley). The supply of nitrogen to the soil is linked to the rhizodeposition of nitrogen via plants roots and the degradation of crop residues after harvest. Our results showed that winter pea exhibited the greatest amount of nitrogen rhizodeposition. However, rhizodeposition did not have a significant impact on rhizospheric microbial communities. Contrary to these observations, the degradation of crop residues significantly modified the composition of bacterial communities linked to their initial biochemical composition. Crop succession including winter pea enriched the soil with mineral nitrogen but simulation with STICS software revealed a nitrogen leaching around of 23 kg N. ha-1 during the cropping cycle. These findings underline the importance of adapting an adequate crop management system, including winter pea, to limit nitrogen losses. The results showed also that wheat yields after winter pea without the use of nitrogen fertilizers were equivalent to those obtained after rapeseed. However, rapeseed required significant nitrogen fertilization. Including winter pea in crop rotation in Normandy region may be a key to enhance productivity, to respond to the challenges of agroecological transition, regional protein autonomy, and to reduce environmental and economic costs, by reducing notably, the costs of fertilizers production and uses
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Vierling-Kovar, Emmanuelle. "Le contrat de société en participation." Phd thesis, Université de Strasbourg, 2013. http://tel.archives-ouvertes.fr/tel-00997288.
Full textAbstract:
La société en participation ne s'analyse pas comme une société classique. Elle ne se dissout pas, elle est résolue ou résiliée, comme tout contrat de partenariat. Sa force, sa réalité, demeure dans le contrat librement choisi par les participants, tant dans son élaboration que dans l'organisation même de la société, situation intermédiaire entre un contrat classique et les sociétés institution. C'est l'application du principe d'autonomie de la volonté. Dans ce cas de figure, l'affectio societatis se rapproche le plus de la notion de jus fraternitatis, du moins lors de l'élaboration des statuts, ce que certains auteurs nomment l'affectio contractus. Finalement, en raison de son caractère éminemment contractuel, à la place de société en participation, ne faudrait-il pas plutôt l'appeler contrat de société en participation ? Il s'agit dès lors de lui reconnaître son caractère de contrat à part entière, un contrat nommé du Code civil. La jurisprudence semble aller dans ce sens.
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Sammoud, Rihab. "La diffusion de la stratégie au sein de l’entreprise : le cas du secteur bancaire." Thesis, Bordeaux 4, 2013. http://www.theses.fr/2013BOR40037.
Full textAbstract:
Ce travail de recherche porte sur la diffusion de la stratégie au sein de la banque. En effet, nous avons cherché à déterminer les étapes clés de la mise en évidence d’un processus de diffusion au sein de la banque, de déterminer les freins que peuvent rencontrés les banquiers lors de ce processus et d’évaluer leur impact sur la mise en oeuvre de la stratégie. En effet, la diffusion est le processus par lequel la stratégie est déclinée à travers toute la banque. Or, la compréhension et le soutien qu’accordent les membres de la banque dépendent, entre autres, du processus grâce auquel iles en prennent connaissance. C’est pourquoi, l’étude de la diffusion apparait pertinente. Ainsi, comprendre en profondeur le processus de la diffusion en termes de modalités et de contenus, nous a permis de détecter les éléments qui peuvent freiner le développement d’une représentation stratégique partagée et comprise par l’ensemble de la banque, de la stratégie envisagée, et influencer la qualité de la mise en oeuvre. Notre analyse s’est essentiellement basée sur une démarche abductive qui consiste à procéder par allers retours entre théorie et terrain et qui nous a permis de renforcer la validité de notre cadre conceptuel et de le compléter par les éléments de notre analyse des cas. Au final, nous avons détecté un ensemble de freins à la diffusion de la stratégie au sein de la banque qui sont essentiellement : la sur information, les capacités cognitives, la résistance au changement, la nature de la stratégie et le nombre des niveaux hiérarchiques et dont l’impact le plus marquant est le dérapage de la mise en oeuvreThis study deals with the communication of strategy within the banking sector. Our aim was to highlight the key steps involved in the communication process of banks, identify the challenges faced by bankers regarding that process and assess their role in the promotion of the strategy. Indeed, communication is the channel through which the strategy will be spread throughout the bank. Yet, the understanding and defense of the strategy by the employees, greatly depends on the way it has been conveyed to them; hence the importance and relevance of communication studies. Thus, a deep understanding of communication processes in terms of form as well as content, allowed us to pinpoint the elements that might prevent the development of a common strategic representation, understood by all, and affect the quality of its implementation. Our study is essentially based on an abductive approach that consists in going back and forth between theory and confirmation on the field. This method allowed us to strengthen the validity of our conceptual framework and supplement it with examples derived from our study case. In the end, we came up with the conclusion that many elements prevent the good circulation of strategy information within a bank. The main ones being: over-information, cognitive capacities, the resistance to change, the nature of the strategy as well as the number of hierarchical levels whose most striking consequence is the failure of implementation
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Aissi, Mohammed. "Conception de circuits WLAN 5 GHZ à résonateurs BAW-FBAR intégrés : oscillateurs et amplificateurs filtrants." Phd thesis, Université Paul Sabatier - Toulouse III, 2006. http://tel.archives-ouvertes.fr/tel-00127363.
Full textAbstract:
Les travaux de recherche présentés dans cette thèse consistent principalement en la conception de fonctions intégrées radiofréquences BiCMOS SiGe exploitant des résonateurs à ondes acoustiques de volume FBAR. Contrairement aux techniques actuelles rencontrées dans l'industrie qui consistent à réaliser des filtres et des résonateurs discrets et à les associer par la suite avec les circuits actifs des émetteurs-récepteurs au niveau du boîtier, nos résonateurs sont directement réalisés sur le substrat silicium des circuits actifs RF par une technique appelée intégration " above-IC ". Avec cette méthode d'intégration, les parasites et la modélisation associés aux microsoudures (Wire Bonding) sont éliminés. Elle permet aussi de se passer des circuits d'interface et d'adaptation nécessaires dans le cas de filtres RF discrets. Ceci permet de réduire considérablement la consommation et le volume des systèmes. Des amplificateurs faible bruit filtrants et des oscillateurs visant le standard WLAN IEEE 802.11a ont ainsi été implantés en utilisant cette technique d'intégration "above IC". Les circuits obtenus sont très compacts, et leurs performances, notamment celles des oscillateurs, sont à l'état de l'art. Par ailleurs, des amplificateurs faible bruit et des VCO LC SiGe intégrés pour application WLAN 5GHz sont également présentés et leurs techniques d'optimisation sont données.
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Augustin, Fougère. "L’altération des minéraux dans les sols forestiers du Bouclier Canadien : quels facteurs environnementaux affectent la variabilité spatiale et temporelle de la mise en solution des cations basiques?" Thèse, 2017. http://hdl.handle.net/1866/20450.
Full text
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Estergaard, Andrea Holly. "Water and material balance at mine tailings impoundments : software program development and risk analysis." Thesis, 1999. http://hdl.handle.net/2429/9158.
Full textAbstract:
Tailings impoundments are commonly used in the mining industry for the disposal and storage
of mine wastes including tailings, waste rock and process water. The impoundments often
require engineered embankment dams to facilitate containment. Failure of impoundment dams
can lead to serious effects downstream due to the release of significant amounts of water and
solids. Inadequate water management has been recognized as the primary cause of such failures.
Tailings impoundment dam design involves estimating the site water and material balance to
design appropriate impoundment structures and material management facilities. The balances
are usually conducted using monthly average hydrologic values and output from the balance are
the required dam crest elevations during the life of the mine.
The "models" that are employed by industry and their consultants to complete these hydrologic
budgets are simple and spreadsheet based, using average hydrologic values to predict required
monthly dam crest elevations. The lack of flexibility and transparency in these spreadsheet
balances has been identified as a problem by mining engineers.
A Microsoft Windows based software program written in Visual Basic, Visual Balance, was
developed as part of this study. Visual Balance is a fast, simple method of modelling the water
and material balance in a single impoundment tailings disposal system and predicting required
dam crest elevations. Visual Balance also includes a risk analysis module which predicts probable impoundment operation and closure conditions based on a Monte Carlo simulation of
expected precipitation and surface runoff values.
Water management problems identified by Visual Balance include insufficient free pond water
available for reclaim, inadequate freeboard, uncontrolled release requirements, or tailings solids
exposure. Knowledge and anticipation of these challenges could influence tailings impoundment
site selection, design, or mine operating conditions. Planning for these conditions in
impoundment and facility design could save companies considerable cost and aggravation.
The results of the five Case Studies conducted as part of this study emphasized the predictive
capabilities of Visual Balance. Monthly dam crest elevations similar to those previously
predicted by spreadsheet based balances were modelled for the five Case Studies by Visual
Balance. In the two Case Studies where actual operating conditions were available for
comparison, insufficient free pond water availability and excess water leading to low freeboards
experienced at each site were successfully predicted by Visual Balance.
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Chang, Yi-Chien. "Systematic approaches to mine, predict and visualize biological functions." Thesis, 2016. https://hdl.handle.net/2144/14501.
Full textAbstract:
With advances in high-throughput technologies and next-generation sequencing, the amount of genomic and proteomic data is dramatically increasing in the post-genomic era. One of the biggest challenges that has arisen is the connection of sequences to their activities and the understanding of their cellular functions and interactions. In this dissertation, I present three different strategies for mining, predicting and visualizing biological functions.
In the first part, I present the COMputational Bridges to Experiments (COMBREX) project, which facilitates the functional annotation of microbial proteins by leveraging the power of scientific community. The goal is to bring computational biologists and biochemists together to expand our knowledge. A database-driven web portal has been built to serve as a hub for the community. Predicted annotations will be deposited into the database and the recommendation system will guide biologists to the predictions whose experimental validation will be more beneficial to our knowledge of microbial proteins. In addition, by taking advantage of the rich content, we develop a web service to help community members enrich their genome annotations.
In the second part, I focus on identifying the genes for enzyme activities that lack genetic details in the major biological databases. Protein sequences are unknown for about one-third of the characterized enzyme activities listed in the EC system, the so-called orphan enzymes. Our approach considers the similarities between enzyme activities, enabling us to deal with broad types of orphan enzymes in eukaryotes. I apply our framework to human orphan enzymes and show that we can successfully fill the knowledge gaps in the human metabolic network.
In the last part, I construct a platform for visually analyzing the eco-system level metabolic network. Most microbes live in a multiple-species environment. The underlying nutrient exchange can be seen as a dynamic eco-system level metabolic network. The complexity of the network poses new visualization challenges. Using the data predicted by Computation Of Microbial Ecosystems in Time and Space (COMETS), I demonstrate that our platform is a powerful tool for investigating the interactions of the microbial community. We apply it to the exploration of a simulated microbial eco-system in the human gut. The result reflects both known knowledge and novel mutualistic interactions, such as the nutrients exchanges between E. coli, C. difficile and L. acidophilus.
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Ju, Anes. "Characterization of Ambra1 heterozygous mice as genetic mouse model of female-specific autism." Doctoral thesis, 2016. http://hdl.handle.net/11858/00-1735-0000-0023-3EFC-A.
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Liu, Ting-Hao, and 劉丁豪. "The Development of Performance Evaluation Indicators for MIS Department Based on Balanced Scorecard Framework." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/j4k83w.
Full textAbstract:
碩士中原大學
資訊管理研究所
91
Currently, to grip the management efficiency on is a major key to survival in an open, competitive and stressed global environment. Thus, to reach their management strategy, the enterprises have to keep a good appraisal and applicative system for the evaluation of their management efficiency. The traditional way in evaluative system is only emphasis on the financial field. Recently, David P. Norton and Robert S. Kaplan issued the Balanced Scorecard (BSC) to research the efficient evaluate system in the future. It is an index including financial aspect, customer aspect, internal business process aspect and learning growth aspect. Obviously, the business process and learning growth are internal balance and others are external balance and therefore it is not only the balance in the past and future development but also the subject and object field. The enterprise strategy and vision have to be as same as information division or it cannot be executed and implemented efficiently. Until now, the accurate index cannot be measured of the information division because the achievements evaluation system of information division still not be developed and cannot tie in the environment changes both internal and external. While they face to the drastic competitive environment, can they measure the entire factor which financial appraisal, customer, internal process and staff learning growth combining the enterprise strategy and vision throughout the BSC? It is a key process to make sure all the staff can strive to work to get a unit as the enterprise strategy. As above mentioned, this essay mission as following: 1.To set a new capability of information appraisal system by using the BSC tool. To analysis a case study understand the current appraisal system and according to the 2.BSC process identify the implemented probability. 3.To sum up all the questions after implement the BSC tool and provide the appropriate suggestions.
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HSIEH, PAI-CHI, and 謝佰機. "A Study for The Integration of Knowledge Attribute Analysis and Balance Score Card -- A Case of MIS Department." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/828hye.
Full textAbstract:
碩士國立臺灣科技大學
資訊管理系
94
This is a case study for a MIS department in the DSC (Digital Still Camera) firm. The researcher used the systems thinking to analyze the problems of this case and then try to come out a solution that integrate both knowledge attribute analysis & balance score card then breaking down it to the executing steps for this case. It is an assessment of any kinds of knowledges for employees in the firm using the knowledge attribute analysis process. According to the result of the audit process, we will know what critical knowledges should be improved and what knowledge gaps should be filled with then developing a performance index for them. Through the knowledge attribute analysis process will come out the critical knowledges and knowledge gaps and then making the performance indexes that formed by balance score card for them to meet the stratigical goals for the firm. The researcher takes the in-depth interview with the external top managers to verify whether it is workable for the solution to solve the problems that the firm met before. Finally, the researcher also hope that it would become a reference model for the other firms to solve the same problems in the future. Key words: Systems Thinking, Knowledge Attribute, Knowledge Audit, Knowledge Management, Balance Score Card
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Chen, Chin-yi, and 陳正義. "A Study of Implementing Balanced Scorecard in Performance measurement of Senior High Schools'' MIS Department." Thesis, 2006. http://ndltd.ncl.edu.tw/handle/39643533538324466893.
Full textAbstract:
碩士義守大學
資訊管理學系碩士班
94
The purpose of this study is to establish balanced scorecard in performance measurement of senior high schools'' MIS Department. We take a broader definition of senior high schools'' MIS Department as “an assembly which brings forth some specific functional activities to fulfill the task of MIS system.” Balanced scorecard used as a measurement tool to assess study subjects, according to its strategy and goal formed by its assignment property, can be divided into four levels: finance, customer, inter process, learning and growth, which can provide us with a timely, efficient, flexible, simple, accurate, and highly overall reliable measurement tool. In order to extract the knowledge and experience from related experts to pick out important evaluation criteria and opinions from other sources, this study puts emphasis on the understanding of every expert’s “semantic thinking process”, from which we make a list of nine semantic scales. The evaluation value follows the filtering and evaluation steps of fuzzy Delphi method to establish trigonometric functions of every evaluated item. After completing weighted calculation of every level and indicator, balanced scorecard model of this study subjects is thus established. The findings of this study show that the indicator weightings between and among all the levels are not the same, rather there exists certain amount of differences. The degrees of attention drawing in order of importance among all levels are customer level, learning and growth level, internal process level, and financial level. After comprehensively analyzing indictors of performance measurement included in every level, the highly valued top three indictors are, when conducting performance measurement in senior high schools'' MIS Department, “highly efficient NIS system,” “the rationalization of both the establishment of software & hardware and maintenance cost,” and “professional trainings and further studies” respectively.
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Hsieh, Hsin-Chih, and 謝欣志. "A Study of Implementing Balanced Scorecard of Government MIS Department－A Case Study of Engineering Department of Government." Thesis, 2008. http://ndltd.ncl.edu.tw/handle/yjyz23.
Full textAbstract:
碩士義守大學
資訊管理學系碩士班
96
The purpose of this study is to establish balanced scorecard in performance measurement of Government MIS Department. Balanced IS scorecard used as a measurement tool to assess study subjects, according to its strategy and goal formed by its assignment property, can be divided into four levels: User orientation, Business value, Internal processes, Future readiness, which can provide us with a timely, efficient, flexible, simple, accurate, and highly overall reliable measurement tool. This research figured out the criterion for evaluating the performance of information department affiliated to public organizations. According to the criterion, a questionnaire was developed to probe into the performance of information department affiliated to public organizations. Questionnaires were dispatched and explanations about the items were given to central level executives. Eleven expert questionnaires were retrieved and analyzed by AHP and Expert choice 2000.After completing weighted calculation of every level and indicator, balanced scorecard model of this study subjects is thus established. The findings of this study show that the indicator weightings between and among all the levels are not the same, rather there exists certain amount of differences. The degrees of attention drawing in order of importance among all levels are internal processes level, user orientation level, business value level and Future readiness After comprehensively analyzing indictors of performance measurement included in every level, the highly valued top three indictors are, when conducting performance measurement in Government MIS Department, “control IS costs,” “satisfy end-user requirements,” and “be efficient in operating and maintaining IT applications” respectively. To make the evaluation of performance not only focused on the essential investment and benefits but also provided tactics for future improvement of information department affiliated to public organizations. Finally, to develop an integrated system of tactics and performance management, utilizing the Balanced Scorecard to construct the criterion for evaluating the information department affiliated to public organizations, attempting to provide public organizations with an easy reference for administrative tactics, so that it is possible to utilize limited budget and resources, making reasonable and suitable distribution and even promoting the whole performance.
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Chang, Chi-Chih, and 張繼直. "The Research of Utilizing Balanced Scorecard of Performance Indicators for MIS Department in the Local Government－A Case of Kaohsiung City Government." Thesis, 2011. http://ndltd.ncl.edu.tw/handle/21341751602366087695.
Full textAbstract:
碩士義守大學
資訊管理學系碩士在職專班
99
The purpose of this study is to establish balanced scorecard in performance measurement of local government'' MIS Department. Performance measures will focus on four levels: business results, financial management, administrative efficiency and organizational learning, which can provide local government MIS departments with an efficient, accurate, flexible, simple and highly overall reliable measurement tool. Through literature review, sorts out the MIS department of the performance measurement and the development of the first stage expert questionnaire. Through the analysis of reliability and validity, the analysis sifted the key performance indicators for the government MIS department and development of the second stage expert questionnaire. Questionnaires were dispatched to the Kaohsiung City Government Information Centre, using Analytic Network Process (ANP) and the Super Decision software to calculate the weight of every indicator and level, for the purpose of establishing balanced scorecard model of this study subjects. The findings of this thesis show that the local government MIS departments’ to the levels varies certain amount of differences. The order of importance among all levels are "business outcomes", "administrative efficiency", "Financial Management", and finally as "organizational learning". After comprehensively analyzing key performance indicators of performance measurement included in every level, the highly valued top three indictors are, when conducting performance measurement in local government MIS department, "information security and privacy," "objectives of achieving rate," " The information provided is timely and correct. "
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Lusambo, Martin. "An integrated model of milling and flotation for the optimal recovery of sulphide ores at the Kansanshi mine." Diss., 2019. http://hdl.handle.net/10500/26692.
Full textAbstract:
Kansanshi mine sulphide ore circuit did not achieve target flotation recovery in
2016, hence it was deemed necessary to carry out a research aimed at optimizing
this circuit. The objective of the research was to optimise the Kansanshi milling
and flotation circuit processing a copper sulphide ore.
In line with this, samples were obtained around the circuit and processed in the
laboratory for moisture content, slurry concentration, particle size distribution,
and flotation response. This information was then used to build a computer-based
model of the Kansanshi milling and flotation circuit. This was done in MODSIM®,
a software package specialising in the design and simulation of mineral processing
operations. After careful appraisal, appropriate models were selected for the semi
autogenous grinding (SAG) and ball mills, SAG mill discharge screen,
hydrocyclones, pebble crusher, and the flotation cells. The calibrated model was
then used to simulate the effects of key operating parameters on flotation
recovery.
Analysis using the attainable region technique revealed that the SAG mill feed-rate
should be adjusted from 1719 tph to 2090 tph. This would lead to a better
utilisation of the pebble crusher that can process 358 tph of pebbles from the
current 198 tph. From the simulation work, it was established that rougher
flotation recovery can be improved from the current 80.0 % to 82.3 %. The technoeconomic benefits of the proposition are yet to be investigated.
Findings from the research concluded that the milling circuit optimum operating
parameter; which generated a final product falling predominantly in the range -
150 +38 μm were SAG and ball mills conditions of ball sizes 200 and 40mm
respectively, ball mill ball filling 32% and rotational speed between 75 and 80% for
both SAG and ball mills. The optimum hydrocyclone feed slurry concentration was
found to be 62% solids. Additionally, the SAG mill discharge screen aperture size
of 6 mm was the optimum. It must be noted that slurry concentration did not show any impact on both the SAG and ball mills performance. The SAG mill ball
filling did not show any significant improvement on performance.College of Engineering, Science and Technology
M. Tech. (Chemical Engineering)
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Tshikovhi, Elelwani Rosemary. "Training and development programme : performance of employees at a South Africa platinum mine." Diss., 2013. http://hdl.handle.net/10500/9044.
Full textAbstract:
This study sought to determine the impact of a training and development (T&D) programme on the perceived performance of human resource assistants at a platinum mine in South Africa according to the following four performance dimensions: (i) personal (ii) customer; (iii) internal business; and (iv) learning and growth. A non-experimental design was used for this study, which was predominately quantitative in nature. Data was collected using a structured, self-administered questionnaire, which consisted of closed-ended questions.
Based on the results obtained in this study, it was apparent that the T&D programme contributed significantly to an increase in the performance of employees. However, there are certain areas that can be improved in order to maximise and optimise the learning of employees. Recommendations were made regarding areas for improvement and possible future research.Human Resource Management
M. Tech. (Human Resources Development)